Digital Commons Network^™

Multi‑View Clustering For Multi‑Omics Data Using Unifed Embedding, Mohammed Hasanuzzaman, Sayantan Mitra, Sriparna Saha

Articles

In real world applications, data sets are often comprised of multiple views, which provide consensus and complementary information to each other. Embedding learning is an effective strategy for nearest neighbour search and dimensionality reduction in large data sets. This paper attempts to learn a unified probability distribution of the points across different views and generates a unified embedding in a low-dimensional space to optimally preserve neighbourhood identity. Probability distributions generated for each point for each view are combined by conflation method to create a single unified distribution. The goal is to approximate this unified distribution as much as possible when …

Interactive Video Vignettes (Ivvs) To Help Students Learn Genetics Concepts, Dina L. Newman, Jean Cardinale, L Kate Wright

Articles

any video resources exist to teach Mendelian genetics, but most consist of passive delivery of information rather than active construction of knowledge by users. We have created two interactive video vignettes (IVVs) that can be used together or separately to introduce students to core concepts of genetics, using principles of active learning (e.g., elicit-confront-resolve, directed feedback, reflection). These online resources are free and can be assigned as homework for students to complete outside of class. Each IVV features a realistic scenario of undergraduate students investigating genetic phenomena by collecting and analyzing data. During the IVVs, the user is integrated into …

Long-Term Effectiveness Of Tree Removal To Re-Establish Sagebrush Steppe Vegetation And Associated Spatial Patterns In Surface Conditions And Soil Hydrologic Properties, C. Jason Williams, Justin C. Johnson, Frederick B. Pierson, Cameron S. Burleson, Viktor O. Polyakov, Patrick R. Kormos, S. Kossi Nouwakpo

Articles

Pinyon (Pinus spp.) and juniper (Juniperus spp.) woodland encroachment into sagebrush (Artemisia spp.) steppe communities throughout western North America has substantially altered the vegetation structure and hydrologic function of one of the most ecologically important rangeland ecosystems in the world. Various pinyon and juniper tree removal practices are employed to re-establish sagebrush steppe vegetation and an associated resource-conserving ecohydrologic function. The effectiveness of these practices is highly variable owing to the vast domain in which woodland encroachment occurs, climate fluctuations, differences in treatment applications, and myriads of pre-treatment conditions and post-treatment land uses. This study evaluated the …

Scandalizing The Judiciary: An Analysis Of The Uneven Response Of The Supreme Court Of India To Sexual Harassment Allegations Against Judges, Sanjay Jain, Saranya Mishra

Articles

The Supreme Court of India (SC) pronounced a momentous judgment in Vishaka v. State of Rajasthan in 1997, categorically recognizing the menace of sexual harassment (SH) at workplace and constitutionally rendering it as being in violation of fundamental rights guaranteed by Articles 15, 19, and 21 of the Constitution of India 1950. The Court also provided a mechanism for redressal against SH, which was ultimately reinforced by Parliament with the enactment of Sexual Harassment at Workplace (Prevention, Prohibition and Redressal) Act 2013 (POSH Act). However, when it comes to allegations of SH against judges in the SC and High Courts …

Using Information Communications Technologies To Implement Universal Design For Learning, David Banes, Anne Hayes, Christopher Kurz, Raja Kashalnagar

Articles

The purpose of this paper is to assist Ministries of Education, their donors and partners, Disabled Persons Organizations (DPOs), and the practitioner community funded by and working with USAID to select, pilot, and (as appropriate) scale up ICT4E solutions to facilitate the implementation of Universal Design for Learning (UDL), with a particular emphasis on supporting students with disabilities to acquire literacy and numeracy skills. The paper focuses primarily on how technology can support foundational skills acquisition for students with disabilities, while also explaining when, why, and how technologies that assist students with disabilities can, in some applications, have positive impacts …

New Bounds On The Real Polynomial Roots, Emil M. Prodanov

Articles

The presented analysis determines several new bounds on the roots of the equation $a_n x^n + a_{n−1} x^{n−1} + · · · + a_0 = 0$ (with $a_n > 0$). All proposed new bounds are lower than the Cauchy bound max $\{ 1, sum_{j=0}^{n-1} | a_j / a_n | \}$. Firstly, the Cauchy bound formula is derived by presenting it in a new light — through a recursion. It is shown that this recursion could be exited at earlier stages and, the earlier the recursion is terminated, the lower the resulting root bound will be. Following a separate analysis, it is …

Does Sars-Cov-2 Infection Cause Chronic Neurological Complications?, Erin R Hascup, Kevin N Hascup

Articles

The current pandemic caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2 has created an unparalleled health crisis. Besides the acute respiratory infection, CoVs are neuroinvasive causing additional inflammation and neurodegeneration. This is likely also true of SARS-CoV-2 given reports of neurological manifestations in coronavirus disease 2019 (COVID-19) positive patients. Older adults > 65 years of age constitute a high-risk group prone to severe infection and death. Despite the higher mortality rate, a majority of cases are expected to recover and survive from this viral outbreak. But, the long-term consequences of SARS-CoV-2 neuroinfection are unknown. We discuss these potential chronic changes to …

What Will (Or Might?) Law School Look Like This Fall?: Teaching In The Midst Of A Pandemic, Ted Becker

Articles

January 2020 marked the start of a new semester for Michigan law schools. There was little reason to suspect it wouldn’t be a semester like any other: for 3Ls, the start of the stretch run to graduation; for 1Ls, a chance to begin anew after the stress of their first set of law school final exams; for law school faculty, administrators, and staff, a return to the excitement and activity of crowded hallways and classrooms after the brief interlude of winter break. Classes began and proceeded as normal.

Federal Forum Provisions And The Internal Affairs Doctrine, Dhruv Aggarwal, Albert H. Choi, Ofer Eldar

Articles

A key question at the intersection of state and federal law is whether corpo- rations can use their charters or bylaws to restrict securities litigation to federal court. In December 2018, the Delaware Chancery Court answered this question in the negative in the landmark decision Sciabacucchi v. Salzberg. The court invalidated “federal forum provisions” (“FFPs”) that allow companies to select federal district courts as the exclusive venue for claims brought under the Secur- ities Act of 1933 (“1933 Act”). The decision held that the internal affairs doc- trine, which is the bedrock of U.S. corporate law, does not permit charter …

Incrementalist Vs. Maximalist Reform: Solitary Confinement Case Studies, Margo Schlanger

Articles

Among criminal justice reformers, it has long been hotly contested whether moderate reform helps or harms more efforts to achieve more thoroughgoing change. With respect to solitary confinement, do partial and ameliorative measures undermine the goal of solitary confinement abolition? Or do reformist campaigns advance—albeit incrementally—that ultimate goal? Call this a debate between “incrementalists” and “maximalists.” I offer this Essay as an appeal for empirical rather than aesthetic inquiry into the question. After summarizing nationwide reform litigation efforts that began in the 1970s, I try to shed some factual light by examining solitary reform efforts in two states, Massachusetts and …

Rhetorical Repetition, Patrick Barry

Articles

When it comes to persuading judges, boardrooms, or even just co-workers, many lawyers shy away from repetition. They remain committed to the idea, often developed in college, that good writing is associated with having (and showing) a big vocabulary. They mistakenly think the best thesaurus wins. This essay explores that error and offers ways to correct it.

Discerning A Dignitary Offense: The Concept Of Equal 'Public Rights' During Reconstruction, Rebecca J. Scott

Articles

The mountain of modern interpretation to which the language of the Fourteenth Amendment of the United States Constitution has been subjected tends to overshadow the multiple concepts of antidiscrimination that were actually circulating at the time of its drafting. Moreover, as authors on race and law have pointed out, Congress itself lacked any African American representatives during the 1866–68 moment of transitional justice. The subsequent development of a “state action doctrine” limiting the reach of federal civil rights enforcement, in turn, eclipsed important contemporary understandings of the harms that Reconstruction-era initiatives sought to combat. In contrast to the oblique language …

Why Women Also Know History, Emily Prifogle, Karin Wulf

Articles

"Women Also Know Stuff. Does that sound obvious? It's not, alas." In early 2016 a group of women political scientists announced in The Washington Post their reasons for forming a group called Women Also Know Stuff. The US presidential election dramatically exposed the ongoing imbalance in the consultation and citation of women experts in political discussion.1 The new group was responding directly to media bias, but it has long been clear that bias—not only against women but against people of color, LGBTQ scholars, and other groups—is persistent in academia. The historical profession is no exception.

Working Hard Or Making Work? Plaintiffs' Attorneys Fees In Securities Fraud Class Actions, Stephen J. Choi, Jessica Erickson, A. C. Pritchard

Articles

In this article, we study attorney fees awarded in the largest securities class actions: “mega- settlements.” Consistent with prior work, we find larger fee awards but lower percentages in these cases. We also find that courts are more likely to reject or modify fee requests made in connection with the largest settlements. We conjecture that this scrutiny provides an incentive for law firms to bill more hours, not to advance the case, but to help justify large fee awards—“make work.” The results of our empirical tests are consistent with plaintiffs’ attorneys investing more time in litigation against larger companies, with …

Consent, Coercion, And Employment Law, Samuel R. Bagenstos

Articles

The Roberts Court has recently handed several high-profile wins in labor and employment law cases to anti-labor and pro-employer forces. This paper argues that those decisions replicate crucial moves made by some infamous Lochner-era cases — and that those same moves continue to underlie key elements of labor and employment doctrine more generally. In particular, these decisions rest on a contestable understanding of free worker choice. This paper begins by examining the key recent Roberts Court decisions and demonstrates that they appear to invoke at least two distinct and conflicting understandings of employee and employer choice. It then turns to …

Winks, Whispers, And Prosecutorial Discretion In Rural Iowa, 1925-1928, Emily Prifogle

Articles

Through the eyes of Charles Pendleton’s memoirs, this article walks through a rural community with a county attorney to consider how race, religion, gender, and sexuality influenced rural prosecutorial discretion in the early twentieth century. Rural communities like those in Buena Vista County, Iowa, where the article is centered, experienced “the law” through distinctly isolated geographies and social networks that lacked anonymity and thus shaped available methods of conflict resolution. But anonymity did not mean homogeneity. Ethnic, racial, and religious diversity created divisions within a community where social distance between individuals was small. Both onymity and diversity shaped who should …

High Flow Nasal Cannula In The Surgical Patient, Morta Lapkus, Paras Khandhar

Articles

No matter how much they want it, airway management and the decision to place a surgical patient on a ventilator should not just be for the PICU physicians to decide. The type of ventilation a patient receives can affect the surgical patient both positively and negatively. Could High Flow Nasal Cannula in the surgical patient be beneficial? Imagine a patient with an esophageal anastomosis that is extubated to CPAP. Now imagine the tears that would flow from the surgeon when they discover bilateral pneumothoraces and a blown-out anastomosis. Tragic. Therefore, we must weigh the risks and benefits of intubation versus …

A New Corporate Tax, Reuven S. Avi-Yonah

Articles

If we can regulate our corporations simply through the medium of taxation, we can destroy every trust in a fortnight. It would be a great deal better for the Finance Committee to turn its attention to the imposition of such a tax upon corporations and the persons who actually need regulation, who are exercising powers that are injurious to the American people, destroying competition and invading our prosperity, than to attempt to levy a revenue tax upon all the little shareholders of all the little corporations throughout the length and breadth of the United States.

Along The Tevere: A Gastro-Historic Portrait Of The Region, Anke Klitzing

Articles

In June 2009, a group of masters students from the University of Gastronomic Sciences in Italy spent nine days visiting the lands of the Tevere river, travelling from its springs on Monte Fumaiolo in Emilia-Romagna to Rome by way of Umbria and the Lake Trasimeno. This article is a gastro-historic portrait of the lands of the Tevere, linking contemporary social, cultural and economic activities around food and tourism to the rich and long history of the region and highlighting persistent patterns, continuity and change.

Assessment Of Dehydration As A Commercial-Scale Food Waste Valorization Strategy, Jon T. Schroeder, Ava L. Labuzetta, Thomas A. Trabold

Articles

Using a commercially available dehydration unit, this study aimed to valorize various food waste streams from different sources in the Rochester, New York area. Dehydration of the food waste collected for the study helped reduce the weight of the feedstock by 70–90%, as the incoming waste streams were relatively wet. The output was materially characterized against end uses such as cattle feed, fish feed, and compost. The results demonstrated that, other than fertilizer, the remaining five end uses (compost, fish feed, cattle feed, pyrolysis, and pelletized fuel) were potentially compatible with varying waste feedstocks based on the parameters analyzed. Fish …

Cell Replacement Strategies For Lithium Ion Battery Packs, Nenad G. Nenadic, Thomas A. Trabold, Michael G. Thurston

Articles

The economic value of high-capacity battery systems, being used in a wide variety of automotive and energy storage applications, is strongly affected by the duration of their service lifetime. Because many battery systems now feature a very large number of individual cells, it is necessary to understand how cell-to-cell interactions can affect durability, and how to best replace poorly performing cells to extend the lifetime of the entire battery pack. This paper first examines the baseline results of aging individual cells, then aging of cells in a representative 3S3P battery pack, and compares them to the results of repaired packs. …

Living With Machines. Ethical Implications And Imaginative Agency As Local Tactics Of Dwelling And Resistance In Everyday Interactions With Artificial Intelligence, Ester Toribio-Roura

Articles

With the widespread of the Internet of things (IoT), algorithms are increasingly managing our everyday life. From navigating our way in cities to keeping track of our health, artificial intelligence has been beneficial to us in many ways. However, its algorithms can also be detrimental as a consequence of biased human programming. The result is that while technological progress delivers more and more human-like artificial intelligence, humans become dehumanised and therefore, disempowered in their everyday interactions with artificial intelligence.The solution(s) is not single-handed and calls for combined interventions at the macro and micro levels. Whilst reviewing recent top-down developments on …

Readiness For Extubation For Pediatric Patients, Ameer Al-Hadidi, Morta Lapkus, Paras Khandar

Articles

Why Should Surgeons Care?

Assessing the readiness for extubation for pediatric patients is not just the decision of the PICU doctors. It must require discussion and agreement of a multi-disciplinary team that includes the operating surgeon and intensivist for the best outcomes. Spontaneous breathing trials are the mainstay of assessing a patient’s readiness for extubation – the entire team must pay close attention to fully understand the readiness for extubation for pediatric patients.

Of course, there are the ‘straight forward’ patients intubated temporarily to obtain imaging, to undergo a necessary procedure, or for protecting an airway during an altered mental …

"I Learned That I Am Loved": Older Adults And Undergraduate Students Mutually Benefit From An Interprofessional Service-Learning Health Promotion Program., Britteny M. Howell, Leslie C. Redmond, Samantha Wanner

Articles

No abstract provided.

Towards Refining Alzheimer's Disease Into Overlapping Subgroups, Erin R. Hascup, Kevin N Hascup

Articles

Alzheimer’s disease (AD) is an age-related neurodegenerative disorder characterized by progressive anterograde amnesia, cerebral atrophy, and eventual death. Current treatment has limited efficacy and cannot decelerate the disease progression. Clinical trials targeting the removal of the neuropathological hallmarks of AD, including accu- mulation of amyloid plaques or neurofibrillary tangles, have failed to modify disease progression. Without new or innovative hypotheses, AD is poised to become a public health crisis within this decade. We present an alternative hypothesis—that AD is the result of multiple interrelated causalities. The intention of this manuscript is to initiate a discussion regarding these multiple causalities and …

Post-Op Day 1 Fever Is Never Atelectasis, Elizabeth Boudiab, Paras Khandhar

Articles

Postop day 1 fever is never atelectasis. It has been blamed for decades while even the latest editions of surgical textbooks disseminate this myth1. Whilst both fever and atelectasis are extraordinarily common after surgery – occurring in up to 40% and 90% of patients, respectively2 this is NOT the cause on Day 1. It is time that we exonerate this myth.

Postop day 1 fever is never atelectasis, it is due to inflammation and trauma of surgery. The concept that atelectasis was causing fever was derived principally from a study showing that alveolar macrophages sampled from an atelectatic rat lung …

Coeliac Disease Pathogenesis: The Uncertainties Of A Well-Known Immune Mediated Disorder, Greg Byrne, Margaret Dunne, Con Feighery, Fernando Chirdo

Articles

Coeliac disease is a common small bowel enteropathy arising in genetically predisposed individuals and caused by ingestion of gluten in the diet. Great advances have been made in understanding the role of the adaptive immune system in response to gluten peptides. Despite detailed knowledge of these adaptive immune mechanisms, the complete series of pathogenic events responsible for development of the tissue lesion remains less certain. This review contributes to the field by discussing additional mechanisms which may also contribute to pathogenesis. These include the production of cytokines such as interleukin-15 by intestinal epithelial cells and local antigen presenting cells as …

An Investigation Of The Role Of Spatial Ability In Representing And Solving Word Problems Among Engineering Students, Gavin Duffy, Sheryl A. Sorby, Brian Bowe

Articles

Background

Spatial ability is significantly related to performance in engineering education. Problem solving, an activity that is highly relevant to engineering education, has been linked to spatial ability.

Purpose/Hypothesis

To what extent is spatial ability related to problem solving among engineering students and how do approaches to problem representation and solution vary with spatial ability level?

Design/Method

Three instruments – a spatial ability test, word math problems and accompanying core math competency questions – were administered to two samples of first year engineering students in two different countries. Data were analyzed at the test level to evaluate the relationship of …

Covid-19, Single-Sourced Diagnostic Tests, And Innovation Policy, Deb Chaarushena, Osman Moneer, Nicholson W. Price Ii

Articles

At the heart of the United States, disastrous response to the Covid-19 pandemic is a failure of diagnostic testing. That something so fundamental to medical care could be so botched evokes incredulity. From primary care offices to critical care settings, every patient encounter begins with a diagnostic workup. Diagnostic testing tools are key parts of the physician’s toolkit, and confirmatory testing is essential. But in the greatest public health challenge of the 21st century, the failures of diagnostic testing have been laid entirely bare.

English Word And Pseudoword Spellings And Phonological Awareness: Detailed Comparisons From Three L1 Writing Systems, Katherine I. Martin, Emily Lawson, Kathryn Carpenter, Elisa Hummer

Articles

Spelling is a fundamental literacy skill facilitating word recognition and thus higher level reading abilities via its support for efficient text processing (Adams, 1990; Joshi et al., 2008; Perfetti and Stafura, 2014). However, relatively little work examines second language (L2) spelling in adults, and even less work examines learners from different first language (L1) writing systems. This is despite the fact that the influence of L1 writing system on L2 literacy skills is well documented (Hudson, 2007; Koda and Zehler, 2008; Grabe, 2009). To address this shortcoming, this study collected data on real word spelling, pseudoword spelling, and phonological awareness …