Digital Commons Network^™

Exploring The Association Of Urban Or Rural County Status And Environmental, Nutrition- And Lifestyle-Related Resources With The Efficacy Of Snap-Ed (Supplemental Nutrition Assistance Program-Education) To Improve Food Security, Rebecca L. Rivera, Jennifer Dunne, Melissa K. Maulding, Qi Wang, Dennis A. Savaiano, Sharon M. Nickols-Richardson, Heather A. Eicher-Miller

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Public Health Nutrition

First Trimester Serum Biomarkers To Predict Gestational Diabetes In A High-Risk Cohort: Striving For Clinically Useful Thresholds, Siobhan M. Corcoran, Natalie Achamallah, John O'Loughlan, Philip Stafford, Pat Dicker, Fergal D. Malone, Fionnuala Breathnach

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Objectives: Screening and diagnosis of gestational diabetes (GDM) has been a source of controversy. The prevalence has increased in line with an obesity epidemic and a trend towards delayed child-bearing. Treatment of even modest glycaemic impairment in pregnancy has been shown to be beneficial in preventing its clinical sequalae. However the cumbersome nature and timing of the oral glucose tolerance test coupled with debate around universal versus risk factor based screening have been problematic. This group aimed to investigate a panel of biomarkers which have shown promise in the literature to predict GDM from the first trimester in a group …

The Relationship Between Early Pregnancy Dietary Intakes And Subsequent Birthweight And Neonatal Adiposity, R.A.K. Kennedy, Laura Mullaney, A.C. O'Higgins, A. Doolan, Daniel Mccartney, M.J. Turner

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Background: Maternal nutrition intakes may influence neonatal birthweight and adiposity; however, inconsistencies within the literature exist. The relationships between maternal dietary intakes in early pregnancy and both birthweight and neonatal adiposity requires elucidation. This study examined the relationship between early pregnancy dietary intakes and subsequent birthweight and neonatal adiposity.

Methods: Women were recruited at their convenience after sonographic confirmation of a singleton pregnancy. Women completed a Willet food frequency questionnaire evaluating habitual food and nutrient intakes at their first antenatal visit. Neonatal body composition was measured using air-displacement plethysmography.

Results: Of the 385 mother-neonate dyads, mean maternal age was 30.8 …

Detection Of “Xisco” Gene For Identification Of Streptococcus Pneumoniae Isolates, Francisco Salvà-Serra, Gwendolyn Connolly, Edward Moore, Lucia Gonzales-Siles

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We describe a PCR-assay differentiating Streptococcus pneumoniae from closely-related species of the Mitis group of the genus Streptococcus and identification of pneumococcus clinical isolates, based on the “Xisco” gene discriminatory marker. The complete “Xisco” gene sequence was observed in all S. pneumoniae genomes analyzed and absent in all non-pneumococcus genomes.

Predictors Of Vitamin D Supplementation Amongst Infants In Ireland Throughout The First Year Of Life, Annemarie Bennett, John M. Kearney

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A prospective observational study was conducted. Self-complete questionnaires recorded socio-demographic characteristics, health behaviours and supplementation practices for 158 mother-infant dyads at 4, 9 and 12 months post-partum. A 2-day food diary was also obtained on 12-month-old infants to examine the contribution of diet to vitamin D intakes.

Factors Associated With Maternal Wellbeing At Four Months Post-Partum In Ireland, Annemarie E. Bennett, John Kearney

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This study aimed to examine factors associated with maternal wellbeing at four months post-partum in the Irish context. Socio-demographic, health behaviour and infant feeding data were collected in pregnancy, at birth and at 17 weeks post-partum. Maternal distress, body image and resilience were measured at 17 weeks post-partum. Binary logistic regression predicted maternal distress and statistical significance was taken at p < 0.05. One hundred and seventy-two women were followed-up in pregnancy, at birth and at 17 weeks post-partum. Three in five (61.6%, n106) initiated breastfeeding. At 17 weeks post-partum, 23.8% (n41) were exclusively or partially breastfeeding and over a third (36.0%, n62) of all mothers were at risk of distress. In multivariate analyses, independent predictors of distress included: low maternal resilience (p < 0.01, odds ratio (OR): 7.22 (95% confidence interval [CI]: 2.49–20.95)); unsatisfactory partner support (p = 0.02, OR: 3.89 (95% CI: 1.20–12.65)); older age (p = 0.02, OR: 1.11 (95% CI: 1.02–1.21)); and breastfeeding (p = 0.01, OR: 2.89 (95% CI: 1.29–6.47)). Routine assessment of emotional wellbeing and targeted interventions are needed to promote a more healthful transition to motherhood among women in Ireland.

Anti-Biofilm Activity Of Antibody Directed Against Surface Antigen Complement Receptor 3-Related Protein-Comparison Of Candida Albicans And Candida Dubliniensis, Jaroslava Chupáčová, Elisa Borghi, Giulia Morace, Agata Los, Helena Bujdáková

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Candida species (spp.) are a part of the normal human microbiota. Candida dubliniensis mostly colonizes the oral cavity and/or respiratory tract (Mahelová and Růžička 2017), especially in HIV-infected individuals (Coleman et al.1997; Sullivan et al.2004; Wahab et al.2014), while Candida albicans is a common inhabitant of the gastrointestinal tract, urogenital tract and oral cavity (Sardi et al.2013; Höfs, Mogavero and Hube 2016). Candidiasis is the most common global fungal infection (Sardi et al.2013). Candida albicans has been isolated in more than 50% of candidiasis; however, the number of non-albicans spp. able to cause serious candidiasis has increased in recent years …

Sodium Caprate Enables The Blood Pressure-Lowering Effect Of Ile- Pro-Pro And Leu-Lys-Pro In Spontaneously Hypertensive Rats By Indirectly Overcoming Pept1 Inhibition, John Gleeson, Jesus Maria Frias, Sinead Ryan, David J. Braydon

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The tripeptides, Ile-Pro-Pro (IPP) and Leu-Lys-Pro (LKP), inhibit angiotensin-converting enzyme (ACE) resulting in lowered blood pressure. Our hypothesis was that the medium chain fatty acid permeation enhancer, sodium caprate (C10), may prevent the decrease in permeability of the tripeptides when PepT1 is inhibited by glycyl-sarcosine (Gly-Sar), a situation that may occur in the presence of food hydrolysates. Using Caco-2 monolayers and isolated rat jejunal tissue, the apparent permeability coefficients (Papp) of [3H]-IPP and [3H]- LKP were assessed in the presence of Gly-Sar with and without C10. Gly-Sar decreased the Papp of both tripeptides across monolayers and isolated jejunal tissue, but …

Effects Of Nonthermal Plasma Technology On Functional Food Components, Aliyu Idris Muhammad, Xinyu Liao, Patrick J. Cullen, Donghong Liu, Qisen Xiang, Jun Wang, Shiguo Chen, Xingqian Ye, Tian Ding

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Understanding the impact of nonthermal plasma (NTP) technology on key nutritional and functional food components is of paramount importance for the successful adoption of the technology by industry. NTP technology (NTPT) has demonstrated marked antimicrobial efficacies with good retention of important physical, chemical, sensory, and nutritional parameters for an array of food products. This paper presents the influence of NTPT on selected functional food components with a focus on low-molecular-weight bioactive compounds and vitamins. We discuss the mechanisms of bioactive compound alteration by plasma-reactive species and classify their influence on vitamins and their antioxidant capacities. The impact of NTP on …

Lignocellulosic Biorefineries In Europe: Current State And Prospects, Amit Jaiswal, Shady Hassan, Gwilym A. Williams

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In 2012, the European Bioeconomy strategy was launched, defining the bioeconomy as "the 33 production of renewable biological resources and the conversion of these resources and waste 34 streams into value added products". This strategy and its action plans increased the turnover 35 of the total bioeconomy in the EU from 2.09 trillion Euro in 2008 to 2.29 trillion in 2015 .

Translation Of Plasma Technology From The Lab To The Food Industry, Patrick J. Cullen, James Lalor, Laurence Scally, Daniela Boehm, Vladimir Milosavljevic, Paula Bourke, Kevin Keener

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The potential of cold plasma as a food processing aid has been demonstrated for a range of processes and products. The potential applications of plasma technology are extensive and include microbial decontamination, pest control, toxin elimination, food and package functionalisation and many others. However, studies reported to date have principally been at laboratory scale. This paper discusses the status and challenges of transferring the technology to the industry. The major challenges discussed for adoption of atmospheric plasma as a food processing tool by industry are (1) demonstration of product/process specific efficacies; (2) development of process compatible technology designs and scale‐up; …

Lactic Acid Fermentation Of Arthrospira PlatensisIs (Spirulina) Biomass For Probiotic-Based Products, Alberto Niccolai, Emer Shannon, Nissreen Abu-Ghannam, Natascia Biondi, Liliana Rodolfi, Mario R. Tredici

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The first objective of this study was to evaluate the use of lyophilised biomass of the cyanobacterium Arthrospira platensis F&M-C256 as the sole substrate for lactic acid fermentation by the probiotic bacterium Lactobacillus plantarum ATCC 8014. After 48 h of fermentation, the bacterial concentration was 10.6 log CFU mL−1 and lactic acid concentration reached 3.7 g L−1. Lyophilised A. platensis F&M-C256 biomass was shown to be a suitable substrate for L. plantarum ATCC 8014 growth. The second objective of the study was to investigate whether lactic acid fermentation could enhance in vitro digestibility and antioxidant activity of A. platensis biomass. …

The Effect Of Non-Thermal Plasma On The Lipid Oxidation And Microbiological Quality Of Sushi, Piotr Kulawik, Carlos Alvarez, Patrick J. Cullen, Ramon Aznar-Roca, Anne Maria Mullen, Brijesh Tiwari

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The study examined the effect of non-thermal plasma (NTP) on the total viable count and lipid oxidation of two common sushi products: nigiri and hosomaki. Sushi samples were treated with NTP using a dielectric barrier discharge system with 70 and 80kV of potential differences for 5min. The samples were stored at 4°C for 11days and analysed for total aerobic count, moisture and protein content, TBA index and fatty acids composition. Although the effect of NTP on the total aerobic counts was not statistically significant, a tendency in log reduction could be observed, with 1–1.5logcfu/g reduction. Moisture and protein content, as …

Spectroscopic Study Of Excited Molecular Nitrogen Generation Due To Interactions Of Metastable Noble Gas Atoms, Laurence Scally, James Lalor, Miroslav Gulan, Patrick J. Cullen, Vladimir Milosavljevic

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This work provides an insight into the generation of excited nitrogen species by allowing noble gases to interact both with one another and ambient air. He and Ar were utilized to generate the optimum selectivity process to create reactive nitrogen species. An optimum setting for the generation of excited molecular nitrogen species, based on their excited energy levels, was obtained when using a mixture of Ar-He at a ratio of 10:1. At that point, when a voltage of 27 kV is applied to the system, it reached the maximum efficiency for selectivity processes to occur which allowed for a greater …

Climate Change Challenges For Land Conservation: Rethinking Conservation Easements, Strategies, And Tools, Jessica Owley, Federico Cheever, Adena R. Rissman, M. Rebecca Shaw, Barton H. Thompson Jr., W. William Weeks

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No abstract provided.

A Comparison Of On-Line And Off-Line Bioaerosol Measurements At A Biowaste Site, Patrick Feeney, Santiago Fernández Rodríguez, Rafael Molina, Eoin Mcgillicuddy, Stig Hellebust, Michael Quirke, Shane Daly, David O'Connor, John Sodeau

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An air measurement campaign was carried out at a green-waste composting site in the South of Ireland during Spring 2016. The aim was to quantify and identify the levels of Primary Biological Aerosol Particles (PBAP) that were present using the traditional off-line, impaction/optical microscopy method alongside an on-line, spectroscopic approach termed WIBS (Wideband Integrated Bioaerosol Sensor), which can provide number concentrations, sizes and “shapes” of airborne PBAP in real-time by use of Light Induced Fluorescence (LIF). The results from the two techniques were compared in order to validate the use of the spectroscopic method for determining the releases of the …

Environmental Impact Assessment Of Pinaceae Airborne Pollen And Green Infrastructure Using Bim, Santiago Fernández-Rodríguez, Juan Pedro Cortés-Pérez, Paloma Prieto Muriel, Rafael Tormo-Molina, J. M. Maya-Manzano

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Urban air quality is a parameter that plays a major role in human health at the local scale. Consequently, in urban planning, the behavior and potential risk of allergenicity for some pollen grains coming from ornamental trees and green spaces surrounding newly built buildings, should be considered. This paper aims to study how pollen exposure, influenced by weather parameters, can be assessed and integrated in the designing and building of constructions as other component of air quality assessment beforehand, by using BIM. Based on a comparative aerobiological study at the height over a building (sampled by two traps at ground …

Pseudorehearsal In Actor-Critic Agents With Neural Network Function Approximation, Vladimir Marochko, Leonard Johard, Manuel Mazzara, Luca Longo

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Catastrophic forgetting has a significant negative impact in reinforcement learning. The purpose of this study is to investigate how pseudorehearsal can change performance of an actor-critic agent with neural-network function approximation. We tested agent in a pole balancing task and compared different pseudorehearsal approaches. We have found that pseudorehearsal can assist learning and decrease forgetting.

Impact Of Cold Chain And Product Variability On Quality Attributes Of Modified Atmosphere Picked Mushrooms (Agaricus Bisporus) Throughout Distribution, Kompal Joshi, Jenna Warby, Juan Valverde, Brijesh Tiwari, Patrick J. Cullen, Jesus Maria Frias

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An integrated mathematical modelling approach was followed to model the heat and mass transfer processes taking place in modified atmosphere packaged mushrooms and its effect on the quality throughout distribution supply chain was simulated. The model equations were solved to obtain the concentration of gases (O2, CO2) and H2O in the headspace of the package. The change in the quality (colour and weight loss) during the distribution supply chain were monitored. The simulation results are in agreement with the experimental data. The model can study the effect of biological parameters and cold chain parameters on the quality of mushroom. Weight …

The Torture Of Children And Adolescents Living And Dying In Guatemala’S Institutions, Madeleine M. Plasencia

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In this article, Professor Madeleine Plasencia examines the legal context of treatment of disabled children in Guatemala living in institutionalized environments. The article explores evidence that children confined in orphanages and other public care facilities in Guatemala endure conditions that violate the provisions against torture and other cruel or degrading treatment or punishment provided under various international instruments, including the Convention on the Rights of the Child. The article discusses the growing world-wide desperation from poverty and food scarcity that drives families to place their children with and without disabilities in state-supported institutions. The article argues that foreign funding and …

Criminalizing Battered Mothers, Courtney K. Cross

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How a domestic violence survivor responds to the abuse she is experiencing depends on many factors. Some critical considerations include her access to resources, desire to stay in her relationship, and assessment of her own safety. Criminal and civil court systems place enormous pressure on survivors to separate from their abusive partners. Not only are survivors with children pressured to leave, they are punished when they stay. That punishment can come in any combination of diminished custody rights, limited parental rights, and incarceration. Yet a survivor who flees with her children is not immune to these same consequences: if she …

A Study Of Hormonal Effects In Cervical Smear Samples Using Raman Spectroscopy, D. Traynor, P. Kearney, I. Ramos, C. M. Martin, J. J. O'Leary, Fiona Lyng

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Raman spectroscopy is a powerful tool that has the potential to be used as a screening method for cervical cancer. It is a label-free, low-cost method providing a biochemical fingerprint of a given sample. The objective of this study was to address patient-to-patient variability contributed by hormonal effects due to the menstrual cycle, the use of hormone-based contraceptives (HC) and the onset of menopause, and to determine if these changes would affect the ability to successfully identify dyskaryotic cells. Raman spectra were recorded from unstained ThinPrep cervical samples (45 cytology negative and 15 high-grade dyskaryosis (high-grade squamous intraepithelial lesion, HSIL) …

A Novel Quantitative Electrochemical Method To Monitor Dna Double-Strand Breaks Caused By A Dna Cleavage Agent At A Dna Sensor, Anna Banasiak, John Cassidy, John Colleran

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Biosensors and Bioelectronics, Vol. 117

Synthesis, Characterisation And Dna Intercalation Studies Of Regioisomers Of Ruthenium (Ii) Polypyridyl Complexes, Laura Perdisatt, Samar Moqadasi, Luke O'Neill, Gary Hessman, Alessandra Ghion, Muhammad Qasim Mushtaq Warraich, Alan Casey, Christine O'Connor

Articles

Regioisomers of the functional group of the main ligand (L) on a series of [Ru(phen)2L]2+and [Ru(bpy)2L]2+ complexes, where phen is 1,10 phenanthroline and bpy is 2,2′-bipyridine, were synthesised to investigate the interaction with deoxyribonucleic acid (DNA) as potential therapeutics. UV–Vis binding titrations, thermal denaturation and circular dichroism were used to evaluate their interaction with DNA. The conclusions indicated the significance of the auxiliary ligand; especially 1,10-phenanthroline has on the binding constants (Kb). The systematic variation of auxiliary ligand(phen or bpy), and polypyridyl ligand (4-(1H-Imidazo[4,5-f][1,10]phenanthrolin-2-yl)benzonitrile (CPIP), 2-(4-formylphenyl)imidazo[4,5-f] [1,10] phenanthroline (FPIP), 2-(4-bromophenyl)imidazo[4,5-f][1,10]phenanthroline (BPIP) and 2-(4-nitrophenyl)imidazo[4,5-f] [1,10] phenanthroline (NPIP), split in terms of …

Developing Deaf Students Fraction Skills Requires Understanding Magnitude And Whole Number Division, Keith Mousley, Ronald R. Kelly

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Research has shown that fraction magnitude and whole number division are important precursors to learning and understanding fractions. Deaf and hard-of-hearing (DHH) students are consistently challenged with learning fractions from K-12 through college. Sixty DHH college students were tested for both their understanding of magnitude between two fractions and their ability to calculate whole number division. The results showed that both understanding the magnitude between two fractions and whole number division are significantly associated with accurately calculating arithmetic functions of fractions with like denominators and different denominators that required them to add, subtract, multiply, and divide two fractions. Understanding fraction …

Measurements Of Radiation Pressure Owing To The Grating Momentum, Ying-Ju Lucy Chu, Eric M. Jansson, Grover A. Swartzlander

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The radiation pressure force on a nearly single-order diffraction grating was measured for a transmission grating near the Littrow angles at wavelengths of 808 and 447 nm. The component of force parallel to the grating agreed well with our prediction, being proportional to the product of the grating order and the ratio of the wavelength and grating period. The normal component of force varied with the incident angle, vanishing near the Littrow angle as expected. The measurements verify a correspondence between the Fourier grating momentum and the mechanical momentum. This Letter provides opportunities for in-space fly-by-light sailcraft as well as …

The Role Of Choice In Weight Loss Strategies: A Systematic Review And Meta-Analysis, Jill. M. Leavy, P. M. Clifton, Jennifer B. Keogh

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Effective strategies to achieve weight loss and long-term weight loss maintenance have proved to be elusive. This systematic review and meta-analysis aims to explore whether the choice of weight loss strategy is associated with greater weight loss. An electronic search was conducted using the MEDLINE (Medical Literature Analysis and Retrieval System Online, or MEDLARS Online), EMBASE (Excerpta Medica database), CINAHL (Cumulative Index to Nursing and Allied Health Literature), and PsycINFO (Database of Abstracts of Literature in the Field of Psychology, produced by the American Psychological Association and distributed on the association’s APA PsycNET) databases for clinical trials and randomized controlled …

Carcinogenesis In Prostate Cancer: The Role Of Long Non-Coding Rnas, John Aird, Anne-Marie Baird, Marvin C.J Lim, Ray Mcdermott, Stephen P. Finn, Steven G. Gray

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LncRNAs appear to play a considerable role in tumourigenesis through regulating key processes in cancer cells such as proliferative signalling, replicative immortality, invasion and metastasis, evasion of growth suppressors, induction of angiogenesis and resistance to apoptosis. LncRNAs have been reported to play a role in prostate cancer, particularly in regulating the androgen receptor signalling pathway. In this review article, we summarise the role of 34 lncRNAs in prostate cancer with a particular focus on their role in the androgen receptor signalling pathway and the epithelial to mesenchymal transition pathway.

Identifying A Novel Role For Fractalkine (Cx3cl1) In Memory Cd8(+) T Cell Accumulation In The Omentum Of Obesity-Associated Cancer Patients, Melissa J. Conroy, Stephen G. Maher, Ashanty M. Ashanty, Suzanne Doyle, Emma K. Foley, John V. Reynolds, Aideen Long, Joanne Lysaght

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The omentum is enriched with pro-inflammatory effector memory CD8+ T cells in patients with the obesity-associated malignancy, esophagogastric adenocarcinoma (EAC) and we have identified the chemokine macrophage inflammatory protein-1alpha as a key player in their active migration to this inflamed tissue. More recently, others have established that subsets of memory CD8+ T cells can be classified based on their surface expression of CX3CR1; the specific receptor for the inflammatory chemokine fractalkine. CD8+ T cells expressing intermediate levels (CX3CR1INT) are defined as peripheral memory, those expressing the highest levels (CX3CR1HI) are effector memory/terminally differentiated and those lacking CX3CR1 (CX3CR1NEG) are classified …

Current And Future Technologies For Microbiological Decontamination Of Cereal Grains, Agatha Los, Dana Ziuzina, Paula Bourke

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Cereal grains are the most important staple foods for mankind worldwide. The constantly increasing annual production and yield is matched by demand for cereals, which is expected to increase drastically along with the global population growth. A critical food safety and quality issue is to minimize the microbiological contamination of grains as it affects cereals both quantitatively and qualitatively. Microorganisms present in cereals can affect the safety, quality, and functional properties of grains. Some molds have the potential to produce harmful mycotoxins and pose a serious health risk for consumers. Therefore, it is essential to reduce cereal grain contamination to …