Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Articles

Discipline
Institution
Keyword
Publication Year

Articles 451 - 480 of 925

Full-Text Articles in Entire DC Network

The Running Performance Profile Of Elite Gaelic Football Match-Play, Shane Malone, Barry Solan, Kieran Collins Jan 2017

The Running Performance Profile Of Elite Gaelic Football Match-Play, Shane Malone, Barry Solan, Kieran Collins

Articles

The current study examined (a) the match running performance of Gaelic football and (b) the decrement in match running performance with respect to position. Global positioning satellite system technologies (4-Hz; VX Sport) were used with 3 elite intercounty teams across 3 full seasons with 250 full game data sets collected. Game movements were classified according to game actions and distance covered across speed zone thresholds (total distance [TD], high-speed running distance [HSRD; ≥17 km·h], sprint distance [SD; ≥22 km·h]; accelerations [n]; peak speed [km·h]). The influence of running performance in each quarter on the subsequent quarter was analyzed across all …


The Relationship Between Technical Performance Indicators And Running Performance In Elite Gaelic Football, Shane Mangan, Martin Ryan, Simon Devenney, Aidan Shovlin, Jason Mcgahan, Shane Malone, Cian O'Neill, Con Burns, Kieran Collins Jan 2017

The Relationship Between Technical Performance Indicators And Running Performance In Elite Gaelic Football, Shane Mangan, Martin Ryan, Simon Devenney, Aidan Shovlin, Jason Mcgahan, Shane Malone, Cian O'Neill, Con Burns, Kieran Collins

Articles

The aim of the current study was to assess whether technical performance relates to positional running demands of elite Gaelic football players. Over a period of three years (2014–2016), four elite Gaelic football teams were monitored using GPS technologies. Four hundred and thirty-two individual player samples were collected from 52 competitive matches. Video analysis software was used to code technical performance indicators in all games. Pearson’s correlations were performed between all technical variables and total distance (m) and high-speed distance (≥17 km h−1). Total ball in play time had small to medium effects (r = .233 to .390, p …


Study Of Phenolic Extractability In Grape Seeds By Means Of Atr-Ftir And Raman Spectroscopy, Julio Nogales-Bueno, Berta Baca-Bocanegra, Abigail Rooney, José Miguel Hernández-Hierro, Hugh Byrne, Francisco José Heredia Jan 2017

Study Of Phenolic Extractability In Grape Seeds By Means Of Atr-Ftir And Raman Spectroscopy, Julio Nogales-Bueno, Berta Baca-Bocanegra, Abigail Rooney, José Miguel Hernández-Hierro, Hugh Byrne, Francisco José Heredia

Articles

Near infrared hyperspectral imaging has been applied to grape seeds in order to select a representative subset of samples according to their spectral features in the 900-1700nm range. Afterwards, selected grape seeds have been classified according to their total phenol and flavanol extractabilities. In this way, samples were sorted in three different groups identified as low, medium and high extractability levels. In order to establish the chemical structures which can be responsible for the different extractabilities, vibrational spectroscopy has been applied to the non-extracted material after seed extractions. Attenuated total reflectance Fourier transform infrared (ATR-FTIR) and Raman spectra of non-extracted …


Linking Atr-Ftir And Raman Features To Phenolic Extractability And Other Attributes In Grape Skin, Hugh Byrne, Abigail Rooney, Julio Nogales-Bueno, Jose Miguel Hernandez-Hierro, Francisco Jose Heredia Jan 2017

Linking Atr-Ftir And Raman Features To Phenolic Extractability And Other Attributes In Grape Skin, Hugh Byrne, Abigail Rooney, Julio Nogales-Bueno, Jose Miguel Hernandez-Hierro, Francisco Jose Heredia

Articles

The importance of wine phenolics on the sensory characteristic of red wines is well-known. Therefore, it is necessary to control the extractability of phenolic compounds from grape skins, which depends significantly on grape ripeness and hence, on cell wall degradation.

In the present study, attenuated total reflectance Fourier transform infrared (ATR-FTIR) and Raman spectra of grape skin have been recorded. Then, these spectral matrices have been studied and the main spectral features have been linked to extractabilities of phenolic compounds (anthocyanins, flavanols and total phenols). Moreover, spectral differences between external and internal grape skin surfaces also have been studied.

It …


Macular Pigment Is Associated With Glare-Affected Visual Function And Central Visual Field Loss In Glaucoma, James Loughman, We Fong Siah, Colm O’Brien Jan 2017

Macular Pigment Is Associated With Glare-Affected Visual Function And Central Visual Field Loss In Glaucoma, James Loughman, We Fong Siah, Colm O’Brien

Articles

Aim

To evaluate the relationship between macular pigment optical density (MPOD) and glare disability in open-angle glaucoma.

Methods A cross-sectional analysis of baseline data (88 subjects; median age, 67 (range 36–84) years) collected during the Macular Pigment and Glaucoma Trial (ISRCTN registry number: 56985060). MPOD at 0.25°, 0.5° and 1° of retinal eccentricity was measured using customised heterochromatic flicker photometry. Mesopic contrast sensitivity with glare (mCSg), photostress recovery time (PRT) and self-reported glare symptoms were evaluated. Fourier-domain optical coherence tomography was used to analyse ganglion cell complex (GCC) and identify foveal involvement.

Results Low spatial frequency (f) mCSg was significantly …


Market Dimensions Of Industrial Juice Production, Anushree Priyadarshini Jan 2017

Market Dimensions Of Industrial Juice Production, Anushree Priyadarshini

Articles

The juice sector is currently demonstrating positive and dynamic growth mainly due to a change in lifestyle, the tendency of consumers to prefer healthy products, and an increase in purchasing power. Fruit juices form part of what are termed the “new age beverages.” In sync with growing consumer inclination toward healthier choices, manufacturers are moving over to healthier ingredients in their juices. Numerous new and innovative products are being launched globally by manufacturers to stimulate sales through innovations in flavor blends, calorie and sweetness levels, and functional benefits, very much shaped by the major lifestyle trends. This chapter aims to …


Nitrate-Rich Beetroot Juice Selectively Lowers Ambulatory Pressures And Ldl Cholesterol In Uncontrolled But Not Controlled Hypertension: A Pilot Study., Conor Kerley, Eamon Dolan, Liam Cormican Jan 2017

Nitrate-Rich Beetroot Juice Selectively Lowers Ambulatory Pressures And Ldl Cholesterol In Uncontrolled But Not Controlled Hypertension: A Pilot Study., Conor Kerley, Eamon Dolan, Liam Cormican

Articles

Background Dietary nitrate has been shown to increase nitrate/nitrite levels in multiple populations, with potential blood pressure lowering effects. However, there are few reports among hypertensives. Aims We aimed to assess the effect of daily nitrate in subject with controlled hypertension vs. uncontrolled hypertension. Methods On day 0, hypertensives wore an ambulatory BP monitor (ABPM) for 24h and fasting blood was taken. Subjects then consumed concentrated beetroot juice (12.9mmol nitrate) for 14 consecutive days. On day 14 subjects consumed their last nitrate dose after fasting blood was drawn and again had an ABPM for 24h. Results According to baseline ABPM, …


Quantification Of Copper Content With Laser Induced Breakdown Spectroscopy As A Potential Indicator Of Offal Adulteration In Beef, Maria Piedad Casado-Gavalda, Yash Dixit, David Geulen, Raquel Cama-Moncunill, Xavier Cama-Moncunill, Maria Markiewicz-Keszycka, Patrick J. Cullen, Carl Sullivan Jan 2017

Quantification Of Copper Content With Laser Induced Breakdown Spectroscopy As A Potential Indicator Of Offal Adulteration In Beef, Maria Piedad Casado-Gavalda, Yash Dixit, David Geulen, Raquel Cama-Moncunill, Xavier Cama-Moncunill, Maria Markiewicz-Keszycka, Patrick J. Cullen, Carl Sullivan

Articles

Laser induced breakdown spectroscopy (LIBS) is an emerging technique in the field of food analysis which provides various advantages such as minimal sample preparation, chemical free, rapid detection, provision of spatial information and portability. In this study, LIBS was employed for quantitative analysis of copper content in minced beef samples spiked with beef liver over three independent batches. Copper content was determined with graphite furnace atomic absorption spectroscopy (GFAAS) in order to obtain reference values for modelling. Partial least square regression (PLSR) was performed to build a calibration and validation model. A calibration model with a high Rcv2 of 0.85 …


Child Rights Trending: Accommodating Children With Disabilities In The Global Human Rights Framework And Us Foreign Policy, Janet E. Lord Jan 2017

Child Rights Trending: Accommodating Children With Disabilities In The Global Human Rights Framework And Us Foreign Policy, Janet E. Lord

Articles

This Article proceeds in three parts. Following the introduction, Part I analyzes the concept of child rights as applied to children with disabilities in instruments antecedent to the CRPD. It goes on to examine the treatment of children with disabilities in the CRC and in the text of the CRPD. In so doing, it exposes the significant conceptual shift in how children with disabilities are characterized as agents and holders of rights in the CRPD, in contrast to prior articulations. Part II explains how this new framework is used to expose and address major human rights issues that face children …


Investigating Industry Expert Discourses On Aspirational Csr Communication, Lisa Koep Jan 2017

Investigating Industry Expert Discourses On Aspirational Csr Communication, Lisa Koep

Articles

Purpose – The purpose of this paper is to investigate industry expert discourses on aspirational corporate social responsibility (CSR) communication. Analysing CSR managers’ and communication consultants’ talk about aspirational talk as constitutive of aspirational CSR communication, the data provide valuable insights into the dominant discourses, and draw attention to the manifold elements in the process of aspirational CSR communication. Design/methodology/approach – Data gathered during 11 in-depth, qualitative interviews with food industry experts in CSR and CSR communication roles in Ireland, the UK and the USA are studied. Findings – The analysis of industry expert discourses suggests that communicating CSR, and …


Meat Quality Of Limousin Young Bulls Slaughtered At 6, 9 And 12 Months Of Age, Maria Markiewicz-Keszycka, Grażyna Czyżak-Runowska, Bożena Grześ, Edward Pospiech, Jolanta Komisarek Jan 2017

Meat Quality Of Limousin Young Bulls Slaughtered At 6, 9 And 12 Months Of Age, Maria Markiewicz-Keszycka, Grażyna Czyżak-Runowska, Bożena Grześ, Edward Pospiech, Jolanta Komisarek

Articles

The aim of this study was to compare the quality of meat of the young Limousin bulls slaughtered at the age of 6, 9 and 12 months, with particular regard to the residual glycogen content in the meat and the value of the glycolytic potential. The study was conducted on bovine longissimus lumborum muscle. The residual glycogen content, glycolytic potential value (96 h post-mortem), pH value (45 min, 24 h, 48 h and 96 h post-mortem), IMP/ATP index (45 min post-mortem), colour parameters (L*, a* and b*), natural and cooking losses, free water content, the chemical composition, sensory parameters (aroma, …


Laser Induced Breakdown Spectroscopy For Quantification Of Sodium And Potassium In Minced Beef: A Potential Technique For Detecting Beef Kidney Adulteration, Y. Dixit, Maria Piedad Casado-Gavalda, R. Cama-Moncunill, Xavier Cama-Moncunill, Maria Markiewicz-Keszycka, Patrick J. Cullen, Carl Sullivan Jan 2017

Laser Induced Breakdown Spectroscopy For Quantification Of Sodium And Potassium In Minced Beef: A Potential Technique For Detecting Beef Kidney Adulteration, Y. Dixit, Maria Piedad Casado-Gavalda, R. Cama-Moncunill, Xavier Cama-Moncunill, Maria Markiewicz-Keszycka, Patrick J. Cullen, Carl Sullivan

Articles

Beef is a rich source of important minerals, with potassium (K) being the most abundant mineral quantitatively except in cured meats where sodium (Na) from the added salt predominates. This study evaluates the capability of LIBS for quantification of the Na and K contents of minced beef as a potential method of detecting beef kidney adulteration. Additionally, the study aims to demonstrate the ability of LIBS to provide spatial mineral information of minced beef. A LIBS system was employed to collect spectral information of adulterated minced beef samples. Atomic absorption spectroscopy (AAS) was used to obtain reference values for Na …


Surface Attachment Of Active Antimicrobial Coatings Onto Conventional Plastic Based Laminates And Performance Assessment Of These Materials On The Storage Life Of Vacuum Packaged Beef Sub-Primals, D. Clarke, A. Tyuftin, M. Cruz-Romero, D. Bolton, S. Fanning, S. K. Pankai, Carmen Bueno-Ferrer, Patrick J. Cullen, J. P. Kerry Jan 2017

Surface Attachment Of Active Antimicrobial Coatings Onto Conventional Plastic Based Laminates And Performance Assessment Of These Materials On The Storage Life Of Vacuum Packaged Beef Sub-Primals, D. Clarke, A. Tyuftin, M. Cruz-Romero, D. Bolton, S. Fanning, S. K. Pankai, Carmen Bueno-Ferrer, Patrick J. Cullen, J. P. Kerry

Articles

Two antimicrobial coatings, namely Sodium octanoate and Auranta FV (a commercial antimicrobial composed of bioflavonoids, citric, malic, lactic, and caprylic acids) were used. These two antimicrobials were surface coated onto the inner polyethylene layer of cold plasma treated polyamide films using beef gelatin as a carrier and coating polymer. This packaging material was then used to vacuum pack beef sub-primal cuts and stored at 4 °C. A control was prepared using the non-coated commercial laminate and the same vacuum packaged sub-primal beef cuts. During storage, microbial and quality assessments were carried out. Sodium octanoate treated packages significantly (p < 0.05) reduced microbial counts for all bacteria tested with an increase of 7 and 14 days, respectively compared to control samples. No significant effect on pH was observed with any treatment. The results suggested that these food grade antimicrobials have the potential to be used in antimicrobial active packaging applications for beef products.


The Antibacterial Activity Of Metal Complexes Containing 1, 10-Phenanthroline: Potential As Alternatire Therapeutics In The Era Of Antibiotic Resistance, Livia Viganon, Orla L. Howe, Pauraic Mccarron, Malachy Mccann, Michael Devereux Jan 2017

The Antibacterial Activity Of Metal Complexes Containing 1, 10-Phenanthroline: Potential As Alternatire Therapeutics In The Era Of Antibiotic Resistance, Livia Viganon, Orla L. Howe, Pauraic Mccarron, Malachy Mccann, Michael Devereux

Articles

The “antibiotic era”, characterized by the overuse and misuse of antibiotics, over the last half-century has culminated in the present critical “era of resistance”. The treatment of bacterial infections is challenging because of a decline in the current arsenal of useful antibiotics and the slow rate of new drug development. The discovery of a new gene (mcr-1) in 2015, which enables bacteria to be highly resistant to polymyxins (such as colistin), the last line of antibiotic defence left, heralds a new level of concern as this gene is susceptible to horizontal gene transfer, with alarming potential to be spread between …


Laser-Induced Breakdown Spectroscopy (Libs) For Food Analysis: A Review, Maria Markiewicz-Keszycka, Xavier Cama-Moncunill, Maria Piedad Casado-Gavalda, Yash Dixit, Raquel Cama-Moncunill, Patrick J. Cullen, Carl Sullivan Jan 2017

Laser-Induced Breakdown Spectroscopy (Libs) For Food Analysis: A Review, Maria Markiewicz-Keszycka, Xavier Cama-Moncunill, Maria Piedad Casado-Gavalda, Yash Dixit, Raquel Cama-Moncunill, Patrick J. Cullen, Carl Sullivan

Articles

Background Laser-induced breakdown spectroscopy (LIBS) is an atomic emission spectroscopic technique which uses a focused pulsed laser beam to generate plasma from the material. The plasma contains atoms, ions and free electrons which emit electromagnetic radiation as the plasma cools down. The emitted light is resolved by a spectrometer to form a spectrum. Recently, LIBS has become an emerging analytical technique for characterisation and identification of materials; its multi-elemental analysis, fast response, remote sensing, little to no sample preparation, low running cost and ease of use make LIBS a promising technique for the food sector.

Scope and approach The present …


The Influence Of Match Outcome On Running Performance In Elite Gaelic Football, Shane Mangan, Shane Malone, Martin Ryan, Jason Mcgahan, Cian O'Neill, Con Burns, Joe Warne, Denise Martin, Kieran Collins Jan 2017

The Influence Of Match Outcome On Running Performance In Elite Gaelic Football, Shane Mangan, Shane Malone, Martin Ryan, Jason Mcgahan, Cian O'Neill, Con Burns, Joe Warne, Denise Martin, Kieran Collins

Articles

Introduction: Match outcome has been linked to running performance in many sports; however, the association has not yet been examined in Gaelic football. Methods: GPS technologies (4-Hz, VX Sport, Lower Hutt, New Zealand) were used with 5 elite Gaelic football teams over a period of 5 years (2012–2016), amounting to 95 matches. In total, 780 full match data sets were collected. Game movements were divided into total distance and high-speed distance (≥17 km h−1). Match outcomes were divided into big losses (≥6 points), small losses (≤5points), draws, small wins (≤5 points) and big wins (≥6 points). Results: Team (P …


Thermostability Of The Coating, Antigen And Immunostimulator In An Adjuvanted Oral Capsule Vaccine Formulation, Stephanie Longet, Vincenzo Aversa, Daire O'Donnell, Joshua Tobias, Monica Rosa, Jan Holmgren, Ivan Coulter, Ed Lavelle Jan 2017

Thermostability Of The Coating, Antigen And Immunostimulator In An Adjuvanted Oral Capsule Vaccine Formulation, Stephanie Longet, Vincenzo Aversa, Daire O'Donnell, Joshua Tobias, Monica Rosa, Jan Holmgren, Ivan Coulter, Ed Lavelle

Articles

Oral vaccines present an attractive alternative to injectable vaccines for enteric diseases due to ease of delivery and the induction of intestinal immunity at the site of infection. However, susceptibility to gastrointestinal proteolysis, limited transepithelial uptake and a lack of clinically acceptable adjuvants present significant challenges. A further challenge to mass vaccination in developing countries is the very expensive requirement to maintain the cold chain. We recently described the effectiveness of a Single Multiple Pill® (SmPill®) adjuvanted capsule approach to enhance the effectiveness of a candidate enterotoxigenic Escherichia coli (ETEC) oral vaccine. Here it was demonstrated that this delivery system …


Monitoring Player Fitness, Fatigue Status And Running Performance During An In-Season Training Camp In Elite Gaelic Football, Shane Malone, Brian Hughes, Mark Roe, Kieran Collins, Martin Buchheit Jan 2017

Monitoring Player Fitness, Fatigue Status And Running Performance During An In-Season Training Camp In Elite Gaelic Football, Shane Malone, Brian Hughes, Mark Roe, Kieran Collins, Martin Buchheit

Articles

Objectives: To examine selected perceptual and physiological measures to monitor fitness, fatigue and running performance during an in-season training camp in elite Gaelic football. Methods: Twenty-two elite Gaelic football players were monitored for training load, perceived ratings of wellness, heart rate variability (HRV; LnSD1), heart rate recovery (HRR), exercise heart rate (HRex), lower limb muscular power (CMJ) and global positioning system (GPS) variables. The Yo-Yo intermittent recovery test level 1 (Yo-YoIR1) was assessed pre and post the training camp. With specific small-sided games (SSG) used as a measure of running performance. Results: During the camp, HRex decreased (−12.2%), HRR increased …


Ethanol Extract Of Blighia Sapida Stem Bark Show Remarkable Prophylactic Activity In Experimental Plasmodium Berghei-Infected Mice., Olayinka O. Otegbade, Johnson A. Ojo, Dolapo I. Adefokun, Oyindamola O. Abiodun, Bolaji N. Thomas, Olusola Ojurongbe Jan 2017

Ethanol Extract Of Blighia Sapida Stem Bark Show Remarkable Prophylactic Activity In Experimental Plasmodium Berghei-Infected Mice., Olayinka O. Otegbade, Johnson A. Ojo, Dolapo I. Adefokun, Oyindamola O. Abiodun, Bolaji N. Thomas, Olusola Ojurongbe

Articles

This work explores the antiplasmodial potential of ethanol extract of Blighia sapida (Lin. Sapindaceae) in chloroquine (CQ)- resistant Plasmodium berghei (ANKA strain)–infected mice. Chloroquine-resistant (ANKA) strain of P berghei was inoculated intraperitoneally into Swiss albino mice. Mice were treated orally for 4 consecutive days, before and after inoculation (prophylactic, suppressive, and curative models) with graded doses of the plant extracts with Artemether-Lumefantrine (Coartem) as control. Prophylactically, the extract showed a remarkable activity in the chemosuppression of P berghei parasites (P


Maternal Nutrient Intakes From Food And Drinks Consumed In Early Pregnancy In Ireland, Laura Mullaney, Shona Cawley, Rachel Kennedy, Amy C. O'Higgins, Daniel Mccartney, Michael J. Turner Jan 2017

Maternal Nutrient Intakes From Food And Drinks Consumed In Early Pregnancy In Ireland, Laura Mullaney, Shona Cawley, Rachel Kennedy, Amy C. O'Higgins, Daniel Mccartney, Michael J. Turner

Articles

Background: The aim of this observational study was to measure food, macronutrient and micronutrient intakes of women presenting for antenatal care and assess compliance with current nutritional recommendations.


Vitamin D Receptor Variants And Uncontrolled Asthma, Conor Kerley, Katrina Hutchinson, John Faul, Peter Greally, David Coghlan, Basil Elnazir, Michael Louw, Yury Rochev Jan 2017

Vitamin D Receptor Variants And Uncontrolled Asthma, Conor Kerley, Katrina Hutchinson, John Faul, Peter Greally, David Coghlan, Basil Elnazir, Michael Louw, Yury Rochev

Articles

BACKGROUND: Asthma is a common childhood respiratory disease, affecting around 20% of Irish children. In other populations, vitamin D receptor (VDR) polymorphisms have been associated with asthma risk. We aimed to investigate the association between 2 VDR polymorphisms and uncontrolled paediatric asthma. METHODS: 44 asthmatic children and 57 healthy volunteers were studied. The VDR TaqI gene variant in exon 9 (T/C) (rs731236) and ApaI (rs7975232) in intron 8 (C/T) were determined, using TaqMan®Assays. The lung function, serum 25-hydroxyvitamin D (25OHD) levels and other biomarkers of allergy, immunity, airway and systemic inflammation were assessed. RESULTS: The distribution of T and C …


Outcomes Of Exclusive Enteral Nutrition In Paediatric Crohn's Disease, L. Lafferty, M. Tuohy, A. Carey, Sheila Sugrue, M. Hurley, Seamus Hussey Jan 2017

Outcomes Of Exclusive Enteral Nutrition In Paediatric Crohn's Disease, L. Lafferty, M. Tuohy, A. Carey, Sheila Sugrue, M. Hurley, Seamus Hussey

Articles

Background/objectives: Exclusive enteral nutrition (EEN) is a safe and effective treatment modality for inducing remission in paediatric Crohn's disease (CD). The primary aim of this study was to compare the outcomes of EEN to corticosteroid (CS) therapy in newly diagnosed, treatment-naïve patients with CD. A secondary aim was to describe the outcomes of EEN in a national cohort of paediatric CD patients over a 10-year period.

Subjects/methods: A retrospective chart review was conducted at the Irish national referral centre for paediatric CD. A case-matched analysis was conducted on two cohorts matched for age, gender, disease location, disease behaviour and disease …


Advances In Control Of Food Mixing Operations, Patrick J. Cullen, Serafim Bakalis, Carl Sullivan Jan 2017

Advances In Control Of Food Mixing Operations, Patrick J. Cullen, Serafim Bakalis, Carl Sullivan

Articles

Mixing is a ubiquitous unit operation within the food industry and employed not only to combine multiple ingredients, but also to control reactions and modify the structure of foods. Failure of the mixing process may result in poor quality, organoleptic or functional attributes of foods along with product safety concerns. The industry is increasingly adopting automation and advanced control strategies such as Process Analytical Technology. Sensors can provide both insights into the complex mechanisms of mixing along with effective control. Here we discuss some recent advances in the control of food mixing operations.


Cancer Incidence In Ireland—The Possible Role Of Diet, Nutrition And Lifestyle, Daniel Mccartney, Declan Byrne, Marie Cantwell, Michael Turner Jan 2017

Cancer Incidence In Ireland—The Possible Role Of Diet, Nutrition And Lifestyle, Daniel Mccartney, Declan Byrne, Marie Cantwell, Michael Turner

Articles

Aim This observational ecological study aims to compare Ireland’s age-specific cancer incidence rates (ASRs) with equivalent European and global data and to highlight possible dietary, nutritional and lifestyle contributors to cancer in Ireland.

Subjects and methods Using the International Agency for Research on Cancer’s (IARC) GLOBOCAN database, Irish ASRs for all-site cancer and for "lifestyle-related" cancers such as those of the colo-rectum, oesophagus, breast, lung and prostate were compared with European and global incidence data. Irish dietary and nutrient intake data were reviewed and evaluated in the context of these cancer incidence data and in relation to the established dietary, …


Vitamin D Improves Selected Metabolic Parameters But Not Neuropsychological Or Quality Of Life Indices In Osa: A Pilot Study, Conor Kerley, Katrina Hutchinson, Jessica Branham, Aisling Mcgowan, John Faul, Liam Cormican Jan 2017

Vitamin D Improves Selected Metabolic Parameters But Not Neuropsychological Or Quality Of Life Indices In Osa: A Pilot Study, Conor Kerley, Katrina Hutchinson, Jessica Branham, Aisling Mcgowan, John Faul, Liam Cormican

Articles

Study Objectives: Our group and others have reported a high rate of vitamin D deficiency in obstructive sleep apnea (OSA), where vitamin D levels (25(OH) D) correlate negatively with OSA severity and some of its associated metabolic alterations. Data regarding vitamin D supplementation in OSA are lacking. We wanted to evaluate the effect of vitamin D3 supplementation on OSA symptoms and metabolic parameters. Methods: We conducted a pilot, double-blind, randomized, placebo-controlled trial of daily supplementation with 4,000 IU vitamin D3 (D3) or placebo (PL). We studied 19 Caucasian adults (14 male, mean age 55 y, mean body mass index [BMI] …


Duration Of Periconceptual Folic Acid Supplementation In Women Booking For Antenatal Care, Shona Cawley, Laura Mullaney, Rachel Kennedy, Maria Farren, Daniel Mccartney, Michael J. Turner Jan 2017

Duration Of Periconceptual Folic Acid Supplementation In Women Booking For Antenatal Care, Shona Cawley, Laura Mullaney, Rachel Kennedy, Maria Farren, Daniel Mccartney, Michael J. Turner

Articles

Objective: To provide accurate estimates of the commencement time, duration and dosage of folic acid (FA) supplementation taken by Irish women in the periconceptional period. The study also aimed to establish the factors associated with optimal FA supplementation practices. Design: Cross-sectional observational study. Women’s clinical and sociodemographic details were computerised. Maternal weight and height were measured before calculating BMI. Detailed FA supplementation questionnaires were completed under the supervision of a trained researcher. Setting: A large university maternity hospital, Republic of Ireland, January 2014–April 2016. Subjects: Women (n 856) recruited at their convenience in the first trimester. Results: While almost all …


1,10-Phenanthroline-5,6-Dione-Based Compounds Are Effective In Disturbing Crucial Physiological Events Of Phialophora Verrucosa, Marcela Queiroz Granato, Diego De Souza Goncalves, Sergio Henrique Seabra, Malachy Mccann, Michael Devereux, Andre Luis De Souza Dos Santos, Lucimar Ferreira Kneipp Jan 2017

1,10-Phenanthroline-5,6-Dione-Based Compounds Are Effective In Disturbing Crucial Physiological Events Of Phialophora Verrucosa, Marcela Queiroz Granato, Diego De Souza Goncalves, Sergio Henrique Seabra, Malachy Mccann, Michael Devereux, Andre Luis De Souza Dos Santos, Lucimar Ferreira Kneipp

Articles

Phialophora verrucosa is a dematiaceous fungus able to cause chromoblastomycosis, phaeohyphomycosis and mycetoma. All these fungal diseases are extremely difficult to treat and often refractory to the current therapeutic approaches. Therefore, there is an urgent necessity to develop new antifungal agents to combat these mycoses. In this context, the aim of the present work was to investigate the effect of 1,10-phenanthroline-5,6-dione (phendione) and its metal-based derivatives [Ag(phendione)2]ClO4 = ([Ag(phendione)2]+) and [Cu(phendione)3](ClO4)2.4H2O = ([Cu(phendione)3]2+) on crucial physiological events of P. verrucosa conidial cells. Using the CLSI protocol, we have shown that phendione, [Ag(phendione)2]+ and [Cu(phendione)3]2+ were able to inhibit fungal proliferation, …


Exploring Smoking, Mental Health And Smoking-Related Disease In A Nationally Representative Sample Of Older Adults In Ireland: A Retrospective Secondary Analysis, Annette Burns, Judith Strawbridge, Luke Clancy, Frank Doyle Jan 2017

Exploring Smoking, Mental Health And Smoking-Related Disease In A Nationally Representative Sample Of Older Adults In Ireland: A Retrospective Secondary Analysis, Annette Burns, Judith Strawbridge, Luke Clancy, Frank Doyle

Articles

Objective

Smoking is the leading preventable cause of death among individuals with mental health difficulties (MHD). The aim of the current study was to determine the impact of smoking on the physical health of older adults with MHD in Ireland and to explore the extent to which smoking mediated or moderated associations between MHD and smoking-related diseases.

Methods

Cross-sectional analysis of a nationally representative sample of 8175 community-dwelling adults aged 50 and over from The Irish Longitudinal Study on Ageing (TILDA) was undertaken. Multivariate adjusted logistic regression models were used to assess the association between MHD, smoking (current/past/never) and smoking-related …


Sarcopenia: Prevalence, And Impact On Operative And Oncologic Outcomes In The Multimodal Management Of Locally Advanced Esophageal Cancer, Jessie Elliott, Suzanne Doyle, Conor Murphy, Sinead King, Emer Guinan, Peter Beddy, Narayanasamy Ravi, John Reynolds Jan 2017

Sarcopenia: Prevalence, And Impact On Operative And Oncologic Outcomes In The Multimodal Management Of Locally Advanced Esophageal Cancer, Jessie Elliott, Suzanne Doyle, Conor Murphy, Sinead King, Emer Guinan, Peter Beddy, Narayanasamy Ravi, John Reynolds

Articles

Objective: The aim of this article was to study the prevalence and significance of sarcopenia in the multimodal management of locally advanced esophageal cancer (LAEC), and to assess its independent impact on operative and oncologic outcomes.

Summary of background data: Sarcopenia in cancer may confer negative outcomes, but its prevalence and impact on modern multimodal regimens for LAEC have not been systematically studied.

Methods: Two hundred fifty-two consecutive patients were studied. Lean body mass (LBM), skeletal muscle index (SMI), and fat mass (FM) were determined pre-treatment, preoperatively, and 1 year postoperatively. Sarcopenia was defined by computed tomography (CT) at L3 …


Preferences Of Women For Web-Based Nutritional Information In Pregnancy, Rachel Ak Kennedy, Laura Mullaney, C.M.E. Reynolds, Shona Cawley, Daniel Mccartney, M.J. Turner Jan 2017

Preferences Of Women For Web-Based Nutritional Information In Pregnancy, Rachel Ak Kennedy, Laura Mullaney, C.M.E. Reynolds, Shona Cawley, Daniel Mccartney, M.J. Turner

Articles

Objectives During pregnancy, women are increasingly turning to web-based resources for information. This study examined the use of web-based nutritional information by women during pregnancy and explored their preferences. Study design Cross-sectional observational study. Methods Women were enrolled at their convenience from a large maternity hospital. Clinical and sociodemographic details were collected and women's use of web-based resources was assessed using a detailed questionnaire. Results Of the 101 women, 41.6% were nulliparous and the mean age was 33.1 years (19–47 years). All women had internet access and only 3% did not own a smartphone. Women derived pregnancy-related nutritional information from …