Digital Commons Network^™

Informed Trading And Its Regulation, Merritt B. Fox, Lawrence R. Glosten, Gabriel V. Rauterberg

Articles

Informed trading--trading on information not yet reflected in a stock's price-- drives the stock market. Such informational advantages can arise from astute analysis of varied pieces of public news, from just released public information, or from confidential information from inside a firm. We argue that these disparate types of trading are all better regulated as part of the broader phenomenon of informed trading. Informed trading makes share prices more accurate, enhancing the allocation of capital, but also makes markets less liquid, which is costly to the efficiency of trade. Informed trading thus poses a fundamental trade-off in how it affects …

The Future Of Law And Mobility, Daniel A. Crane

Articles

With the launch of the new Journal of Law and Mobility, the University of Michigan is recognizing the transformative impact of new transportation and mobility technologies, from cars, to trucks, to pedestrians, to drones. The coming transition towards intelligent, automated, and connected mobility systems will transform not only the way people and goods move about, but also the way human safety, privacy, and security are protected, cities are organized, machines and people are connected, and the public and private spheres are defined.

An Investigation Of The Benefits And Barriers Of E‐Business Adoption Activities In Yemeni Smes, Ahmed Abdullah, Brychan Thomas, Lyndon Murphy, Eoin Plant

Articles

Yemeni small‐ and medium‐sized enterprises (SMEs) are at the early stages of e‐business adoption and their owners and managers need to be supported to gain an understanding of the benefits that their business can achieve from adopting e‐business. Yemeni SMEs are at the early stages of e‐business adoption. The delay in adopting more advanced e‐business solutions are due to factors including the comparatively low level of technology usage within the organization, lack of qualified staff available to develop, implement and support firms’ websites, and limited financial resources. A lack of computer software and hardware resources appears to have a detrimental …

Laboratoire DéBerlinisation: Art, Finance, And The Legacies Of Colonialism In Contemporary African Art: An Interview With Mansour Ciss Kanakassy, Conor Mcgarrigle, Marisa Lerer

Articles

Mansour Ciss Kanakassy (b. 1957) is a Berlin-based Senegalese artist whose practice addresses the legacy of colonialism in contemporary Africa, in particular as it is expressed in the financial systems of the former Francophone colonies of West Africa, where the currency, the CFA franc, historically tied to the French franc, is now pegged to the euro. The acronym CFA originally stood for Colonies Françaises d’Afrique – French Colonies of Africa – and now Communauté Financière Africaine – African Financial Community. In 2001, Ciss Kanakassy created the Laboratoire Déberlinisation (Déberlinisation Laboratory), a multifaceted project that traces contemporary African issues to the …

Spontaneous Hair Cell Regeneration Is Prevented By Increased Notch Signaling In Supporting Cells, Melissa M. Mcgovern, Luyi Zhou, Michelle R. Randle, Brandon C Cox

Articles

During embryonic development, differentiation of cochlear progenitor cells into hair cells (HCs) or supporting cells (SCs) is partially controlled through Notch signaling. Many studies have shown that inhibition of Notch signaling allows SCs to convert into HCs in both normal and drug damaged neonatal mouse cochleae. This mechanism is also implicated during HC regeneration in non-mammalian vertebrates; however, the mechanism of spontaneous HC regeneration in the neonatal mouse cochlea is less understood. While inhibition of Notch signaling can force SCs to convert into HCs and increase the number of regenerated HCs, it is currently unknown whether this pathway is involved …

Irish Cuisine: Irish Diplomatic Dining, Elaine Mahon

Articles

The study of food and power has primarily focused on absolutist courts with powerful monarchs and a wealthy court life, yet contemporary research into the emergent power structures of the nineteenth and twentieth centuries shows that dining remains an important feature in political and state life. Using new archival material, in particular that of the Irish Department of External Affairs, this paper will examine the emergence of Irish diplomatic dining since the foundation of the Irish Free State and explore how the Irish government established state policy for receiving important visitors. The paper will focus on the principal cultural, political …

Recurrent Idiopathic Anaphylaxis In A Woman After Suspected Food Poisoning, Carl B. Lauter, Shalini Koppisetty

Articles

Rationale:Recurrent idiopathic anaphylaxis represents a vexing clinical problem associated with stress for patients and allergists. The cause is often not identified despite exhaustive testing. Methods The history of a 54-year old woman with repeated bouts of unexplained anaphylaxis is reviewed. The relationship between preceding or active infection (emphasis on gastrointestinal infections) and chronic idiopathic urticaria and anaphylaxis was explored by electronic media search (PubMed, Google) and review of reference lists of published articles. The literature on the relationship of Campylobacter jejuni infection and urticaria is reviewed. Gastrointestinal infections (Giardia, Anisakis) have been better documented in such patients. Results The patient …

Parental Attitudes To Myopia: A Key Agent Of Change For Myopia Control?, Saoirse Mccrann, Daniel Ian Flitcroft, Kevin Lalor, John Butler, Aaron Bush, James Loughman

Articles

Purpose

With the increasing prevalence in myopia there is growing interest in active myopia prevention. This study aims to increase our understanding of parental attitudes to myopia development and control, as a means to inform future health planning and policy. It evaluates, for the first time, the attitude of parents to myopia and its associated risks, as well as assessing the exposure of Irish children to environmental factors that may influence their risk profile for myopia development.

Methods

Parents of 8–13 year old children in eight participating schools completed a questionnaire designed to assess their knowledge of and attitudes towards …

James Connolly's Bloodstained Vest: Mediating Death And Violence In Commemorative Exhibitions, Siobhan Doyle

Articles

The actions surrounding the display of images and artefacts in museums – collection, conservation, research and exhibition – are bound up with how the past is presented and remembered. These conditions and decisions relating to exhibitions are largely invisible to viewers who are confronted with the apparent completeness of an exhibition display. By conducting a historical and visual analysis of the bloodstained vest of political leader James Connolly, this article uncovers how this artefact has become a relic of historical violence due to the way in which particular aspects of its configuration, form and trajectory have been manipulated in order …

Art Interventions And Disruptions In Financial Systems: An Interview With Paolo Cirio, Marisa Lerer, Conor Mcgarrigle

Articles

Prior to the release of the 2016 Panama Papers and 2017 Paradise Papers – leaked documents that uncovered the movement of funds through offshore tax havens – conceptual artist Paolo Cirio’s (b. 1979) project Loophole for All (2013) revealed and documented the mechanics behind offshore financial centers. In this interview, Cirio expounds upon his investigations of offshore banking practices, describes his projects for instituting alternative financial models, and explains his hacktivist (i.e. Internet activist) strategies that engage with legal and economic systems. Defining the foundational movements that inform his work, Cirio in turn illuminates his methods of direct provocation and …

The Us’S Economic Promises Are Over: An Interview With Miguel Luciano, Marisa Lerer, Conor Mcgarrigle

Articles

Hurricane Maria struck Puerto Rico in September 2017. The island was left without electricity and clean water for months. However, the natural disaster was not the only cause of this lasting devastation. The financial fall-out from predatory loans, which led to Puerto Rico’s inability to invest funds in its own infrastructure, caused an enduring humanitarian disaster. Artist Miguel Luciano (b. 1972) in this interview discusses his work in relation to the 2017 Puerto Rican debt crisis and the legacy of the over 100-year span of Puerto Rico’s colonial status as a US territory, which gives the US disproportionate control over …

Insurgent Finances: An Interview With Gabriela Ceja And Fran Ilich, Marisa Lerer, Conor Mcgarrigle

Articles

When the financial crisis of 2008 exposed the opaque workings of global financial markets, it led to calls for alternate economic models to replace the excesses of contemporary capitalism. A decade on, it can seem that those calls went unheeded. However, in the collaborative social practice of Fran Ilich and Gabriela Ceja, sustainable alternatives modeled on ancient modes of exchange are being developed with projects that are deeply embedded in economic practice; whether that is running a functioning microbank complete with complex financial instruments in Spacebank or serving Zapatista coffee from Chiapas, Mexico in the Diego de la Vega Coffee …

Democratic Erosion And The Courts: Comparative Perspectives, Aziz Huq

Articles

No abstract provided.

Conformational Studies Of Gram-Negative Bacterial Quorum Sensing Acyl Homoserine Lactone (Ahl) Molecules: The Importance Of The N→* Interaction, Fintan Kelleher, Goar Sánchez-Sanz, Darren Crowe, Alan Nicholson, Adrienne Fleming

Articles

A ¹H NMR study shows the presence of intermolecular hydrogen bonds for AHLs in CDCl₃ solution. A detailed computational study of the structure of AHLs and the relative stability between the extended conformations (X) and those showing n→p* interactions (np) have been carried out by means of DFT calculations. Solvent effects have been shown to be very important when stabilising np conformations, particularly with polar solvents. This was shown by the shortening of C···O intramolecular distances and the increase in the relative energies favouring the np conformation with the dielectric constant of the solvent. …

Events, Social Connections, Place Identities And Extended Families, Bernadette Quinn, Theresa Ryan

Articles

The study reported here investigates the role that planned social gatherings play in shaping social connections, forging group identity and re-affirming connections with significant ‘home’ places within families where relationships extend across space. Empirically, it draws on a study of the Gathering, a 2013 national tourism initiative that encouraged people in Ireland to organise ‘gatherings’ to attract ‘home’ family members scattered across the globe. It reports data generated using mixed methods administered in two Irish counties. The findings demonstrate the profound meanings that the gatherings had for participating family members. The events served to strengthen existing family ties and to …

The Self And Other: Portraying Israeli And Palestinian Identities On Twitter, Jason Deegan, John Hogan, Sharon Feeney, Brendan Orourke

Articles

The conflict between Israel and Palestine has lasted over half a century, with both sides enduring military and political turmoil. This paper explores how Twitter is being used as a medium to portray identities in the conflict. We examine the tweets contained in the @IDFspokesperson and @ISMPalestine Twitter accounts between late 2015 and early 2016. Using textual analysis, we gain an insight into how these Twitter accounts, defined by the conflict, are used in portraying the self and the other.

Enzymatic Extraction Of Fucoxanthin From Brown Seaweeds, Emer Shannon, Nissreen Abu-Ghannam

Articles

Brown seaweeds contain a number of bioactive compounds. The xanthophyll, fucoxanthin, has in vivo efficacy against disorders such as type 2 diabetes, obesity and cancer. Organic solvents are traditionally employed to extract fucoxanthin, but carry a toxic chemical and environmental burden. The aim of this study was to optimise a fucoxanthin extraction method using enzymes, water, low-temperature dehydration and mechanical blending, to produce yields comparable to those achieved with an organic solvent (acetone). Response surface methodology was applied, using Fucus vesiculosus as a model species. A fucoxanthin yield of 0.657 mg g^-1 (dry mass) was obtained from F. …

Quantifying Partisan Gerrymandering: An Evaluation Of The Efficiency Gap Proposal, Benjamin Plener Cover

Articles

Electoral districting presents a risk of partisan gerrymandering: the manipulation of electoral boundaries to favor one political party over another. For three decades, the U.S. Supreme Court has failed to settle on a legal test for partisan gerrymandering, and such claims have uniformly failed. Until recently. Plaintiffs prevailed before a three-judge federal panel in Wisconsin by leveraging a new measure called the "efficiency gap," which quantifies partisan gerrymandering in terms of two parties' relative efficiency at translating votes for their party into seats in government. The case is now before the Court, which may embrace the efficiency gap approach and …

Pardoning Immigrants, Peter L. Markowitz, Lindsay Nash

Articles

In the waning days of the Obama Administration, with Trump’s promised immigration crackdown looming, over one hundred advocacy organizations joined forces to urge President Obama to permanently protect hundreds of thousands of immigrants from deportation by pardoning their breaches of civil immigration law. That pardon never materialized and, as expected, the Trump enforcement regime is sowing terror and devastation in immigrant communities nationwide. While it seems unfathomable that the current president would use his pardon power to mitigate even the most extreme applications of our nation’s immigration laws, there is unfortunately no indication that the harshest aspects of the immigration …

Limited Distribution Networks Stifle Competition In The Generic And Biosimilar Drug Industries, Laura Karas, Kenneth M. Shermock, Celia Proctor, Mariana Socal, Gerard F. Anderson

Articles

A limited distribution network (LDN) restricts the distribution channel for a pharmaceutical drug to 1 or a very small number of distributors. This strategy may allow for more effective allocation of drugs in shortage and is purported to help ensure the safe distribution of high-risk drugs to small patient populations. However, in recent years, some drug companies, including Turing Pharmaceuticals, have used LDNs to prevent generic and biosimilar companies from accessing samples of drug products necessary to perform testing required by the FDA for generic and biosimilar drug applications. LDNs also hamper provider access to pharmaceuticals and facilitate price gouging. …

The Influence Of Government Defenders On Affirmative Civil Rights Enforcement, Alexander A. Reinert

Articles

The federal government — in particular the Department of Justice — can be one of the most efficient and powerful vindicators of civil rights, while simultaneously one of the most effective advocates for imposing barriers to affirmative civil rights enforcement. At the same time that the DOJ’s Civil Rights Division (CRD) is entering federal court to vindicate important rights, attorneys in the Civil Division (either from Main Justice or in any number of U.S. Attorney’s offices) are appearing in court to prevent the same. No doubt a similar pattern can be observed in certain state governments that have active affirmative …

Dispute System Design Can Help: To Bring About The Future Envisioned By Gpc Participants, We Need To Change The Structure Of What We Do, Lela P. Love, Lisa Blomgren Amsler, Mansi Karol

Articles

No abstract provided.

Cold Atmospheric Plasma Induces Atp-Dependent Endocytosis Of Nanoparticles And Synergistic U373mg Cancer Cell Death, Zhonglei He, Kangze Liu, Eline Manaloto, Alan Casey, George P. Cribaro, Hugh Byrne, Furong Tian, Carlos Barcia, Gillian Conway, Patrick J. Cullen, James Curtin

Articles

Gold nanoparticles (AuNP) have potential as both diagnostic and therapeutic vehicles. However, selective targeting and uptake in cancer cells remains challenging. Cold atmospheric plasma (CAP) can be combined with AuNP to achieve synergistic anti-cancer cytotoxicity. To explore synergistic mechanisms, we demonstrate both rate of AuNP uptake and total amount accumulated in U373MG Glioblastoma multiforme (GBM) cells are signifcantly increased when exposed to 75kV CAP generated by dielectric barrier discharge. No signifcant changes in the physical parameters of AuNP were caused by CAP but active transport mechanisms were stimulated in cells. Unlike many other biological efects of CAP, long-lived reactive species …

Accountability Claims In Constitutional Law, Nicholas Stephanopoulos

Articles

No abstract provided.

Reframing The Mediation Debate In Irish All-Issues Divorce Disputes: From Mediation Vs. Litigation To Mediation And Litigation, Deirdre Mcgowan

Articles

Mediation currently plays a minor role in the Irish family justice system, yet a policy consensus exists that more couples should be encouraged to mediate and that increased rates of mediation will reduce the numbers seeking redress through the courts. The recently published Mediation Act 2017 adopts this position, assuming that the provision of information on mediation will increase uptake and that mediation offers an alternative to litigation for most civil disputes. This article reviews attempts in Ireland, England and Wales to encourage family disputants to mediate, identifying weaknesses in the information strategy. It also examines the legal framework governing …

The Fortification Of Inequality: Constitutional Doctrine And The Political Economy, Kate Andrias

Articles

As Parts I and II of this Essay elaborate, the examination yields three observations of relevance to constitutional law more generally: First, judge-made constitutional doctrine, though by no means the primary cause of rising inequality, has played an important role in reinforcing and exacerbating it. Judges have acquiesced to legislatively structured economic inequality, while also restricting the ability of legislatures to remedy it. Second, while economic inequality has become a cause célèbre only in the last few years, much of the constitutional doctrine that has contributed to its flourishing is longstanding. Moreover, for several decades, even the Court’s more liberal …

Liminal Entrepreneuring: The Creative Practices Of Nascent Necessity Entrepreneurs, Lucia Garcia-Lorenzo, Paul Donnelly, Lucia Sell-Trujillo, J. Miguel Imas

Articles

This paper contributes to creative entrepreneurship studies through exploring ‘liminal entrepreneuring’, i.e., the organization-creation entrepreneurial practices and narratives of individuals living in precarious conditions. Drawing on a processual approach to entrepreneurship and Turner’s liminality concept, we study the transition from un(der)employment to entrepreneurship of 50 nascent necessity entrepreneurs (NNEs) in Spain, the United Kingdom, and Ireland. The paper asks how these agents develop creative entrepreneuring practices in their efforts to overcome their condition of ‘necessity’. The analysis shows how, in their everyday liminal entrepreneuring, NNEs disassemble their identities and social positions, experiment with new relationships and alternative visions of themselves, …

Socialising Economic Development In Ireland: Social Enterprise An Untapped Resource, Gerard Joseph Doyle

Articles

The chapter provides a comprehensive explanatory framework outlining why social enterprises have been underutilised by policy-makers in Ireland. The Irish State has afforded social enterprise a narrow role in realising the State’s social and economic objectives. It is incumbent upon community organisations to demand that the State has a change of policy direction towards social enterprise, where its current residual role is replaced by a more central role in economic development. The chapter provides an analysis of the factors which led to the growth of the credit union movement in Ireland. Lessons from the development of Ireland’s credit union movement …

How To Lose A Constitutional Democracy, Aziz Huq, Tom Ginsburg

Articles

No abstract provided.

Secrecy And Randomness: Encoding Cloud Data Locally Using A One-Time Pad, Paul Tobin, Lee Edward Tobin, Mick Mckeever, Jonathan Blackledge

Articles

There is no secrecy without randomness, and we address poor cloud security using an analogue chaotic onetime pad encryption system to achieve perfect secrecy. Local encoding returns control to the client and makes stored cloud data unreadable to an adversary. Most cloud service providers encode client data using public encryption algorithms, but ultimately businesses and organisations are responsible for encoding data locally before uploading to the Cloud. As recommended by the Cloud Security Alliance, companies employing authentication and local encryption will reduce or eliminate, EU fines for late data breach discoveries when the EU implements the new general data protection …