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The Many Faces Of Modern Legal Realism, Brian Bix Jan 2022

The Many Faces Of Modern Legal Realism, Brian Bix

Articles

This work offers an overview of the consequences and implications of the work of the American Legal Realists. First, the article considers Brian Leiter’s naturalist understanding of the realist project and how he uses it as an occasion to argue for a generally naturalist approach to legal philosophy. Second, Frederick Schauer transforms a legal realist-like focus on the concerns of average citizens for legal enforcement to advocate for the view that coercion is central to understanding law. Third, self-styled New Legal Realists try to merge a realist-inspired search for the effects of legal rules with a more traditional respect for …


Chatgpt Goes To Law School, Jonathan Choi, Kristin E. Hickman, Amy B. Monahan, Daniel Benjamin Schwarcz Jan 2022

Chatgpt Goes To Law School, Jonathan Choi, Kristin E. Hickman, Amy B. Monahan, Daniel Benjamin Schwarcz

Articles

How well can AI models write law school exams without human assistance? To find out, we used the widely publicized AI model ChatGPT to generate answers to the final exams for four classes at the University of Minnesota Law School. We then blindly graded these exams as part of our regular grading processes for each class. Over ninety-five multiple-choice questions and twelve essay questions, ChatGPT performed on average at the level of a C+ student, achieving a low but passing grade in all four courses. After detailing these results, we discuss their implications for legal education and lawyering. We also …


Promoting Patent Practitioner Diversity: Expanding Non-Jd Pathways And Removing Barriers, Christopher M. Turoski Jan 2022

Promoting Patent Practitioner Diversity: Expanding Non-Jd Pathways And Removing Barriers, Christopher M. Turoski

Articles

No abstract provided.


Preparing Engineering Students For The Challenges Of The Sdgs: What Competences Are Required?, Una Beagon, Klara Kövesi, Brad Tabas, Bente Nørgaard, Riitta Lehtinen, Brian Bowe, Christiane Gillet, Claus Monrad Spliid Jan 2022

Preparing Engineering Students For The Challenges Of The Sdgs: What Competences Are Required?, Una Beagon, Klara Kövesi, Brad Tabas, Bente Nørgaard, Riitta Lehtinen, Brian Bowe, Christiane Gillet, Claus Monrad Spliid

Articles

Despite the emerging discussions about the growing role of engineers in achieving the Sustainable Development Goals (SDGs), there is a lack of agreement on which competences should be prioritised to prepare engineering students to resolve future sustainability challenges. This study examined and compared the views of key stakeholders of engineering education (Academics, Employers and Students) using twelve focus groups in Denmark, Finland, France and Ireland. The findings were mapped against competences identified in previous studies to highlight gaps and opportunities for development. The results confirm the strong emphasis on normative, strategic and systems thinking competences in engineering. However, the outcomes …


Towards Exchanging Wearable-Pghd With Ehrs: Developing A Standardized Information Model For Wearable-Based Patient Generated Health Data, Abdullahi Abubakar Kawu, Dympna O'Sullivan, Lucy Hederman Jan 2022

Towards Exchanging Wearable-Pghd With Ehrs: Developing A Standardized Information Model For Wearable-Based Patient Generated Health Data, Abdullahi Abubakar Kawu, Dympna O'Sullivan, Lucy Hederman

Articles

Wearables have become commonplace for tracking and making sense of patient lifestyle, wellbeing and health data. Most of this tracking is done by individuals outside of clinical settings, however some data from wearables may be useful in a clinical context. As such, wearables may be considered a prominent source of Patient Generated Health Data (PGHD). Studies have attempted to maximize the use of the data from wearables including integrating with Electronic Health Records (EHRs). However, usually a limited number of wearables are considered for integration and, in many cases, only one brand is investigated. In addition, we find limited studies …


Residential Demand Side Management Model, Optimization And Future Perspective: A Review, Subhasis Panda, Sarthak Mohanty, Pravat Kumar Rout, Binod Kumar Sahu, Mohit Bajaj, Dr Hossam Zawbaa, Salah Kamel Jan 2022

Residential Demand Side Management Model, Optimization And Future Perspective: A Review, Subhasis Panda, Sarthak Mohanty, Pravat Kumar Rout, Binod Kumar Sahu, Mohit Bajaj, Dr Hossam Zawbaa, Salah Kamel

Articles

The residential load sector plays a vital role in terms of its impact on overall power balance, stability, and efficient power management. However, the load dynamics of the energy demand of residential users are always nonlinear, uncontrollable, and inelastic concerning power grid regulation and management. The integration of distributed generations (DGs) and advancement of information and communication technology (ICT) even though handles the related issues and challenges up to some extent, till the flexibility, energy management and scheduling with better planning are necessary for the residential sector to achieve better grid stability and efficiency. To address these issues, it is …


An Image Processing Based Classifier To Support Safe Dropping For Delivery-By-Drone, Assem A. Abdelhak, Alan Hicks, Dan Moss, Susan Mckeever Jan 2022

An Image Processing Based Classifier To Support Safe Dropping For Delivery-By-Drone, Assem A. Abdelhak, Alan Hicks, Dan Moss, Susan Mckeever

Articles

Autonomous delivery-by-drone of packages is an active area of research and commercial development. However, the assessment of safe dropping/ delivery zones has received limited attention. Ensuring that the dropping zone is a safe area for dropping, and continues to stay safe during the dropping process is key to safe delivery. This paper proposes a simple and fast classifier to assess the safety of a designated dropping zone before and during the dropping operation, using a single onboard camera. This classifier is, as far as we can tell, the first to address the problem of safety assessment at the point of …


Hamiltonian Approach To Modelling Interfacial Internal Waves Over Variable Bottom, Rossen Ivanov, Calin Martin, Michail Todorov Jan 2022

Hamiltonian Approach To Modelling Interfacial Internal Waves Over Variable Bottom, Rossen Ivanov, Calin Martin, Michail Todorov

Articles

We study the effects of an uneven bottom on the internal wave propagation in the presence of stratification and underlying non-uniform currents. Thus, the presented models incorporate vorticity (wave–current interactions), geophysical effects (Coriolis force) and a variable bathymetry. An example of the physical situation described above is well illustrated by the equatorial internal waves in the presence of the Equatorial Undercurrent (EUC). We find that the interface (physically coinciding with the thermocline and the pycnocline) satisfies in the long wave approximation a KdV–mKdV type equation with variable coefficients. The soliton propagation over variable depth leads to effects such as soliton …


Neuromatch Academy: A 3-Week, Online Summer School In Computational Neuroscience, Bernard Marius 'T Hart, Titipat Achakulvisut, Ayoade Adeyemi, Athena Akrami, Bradly Alicea, Alicia Alonso-Andres, Diego Alzate-Correa, Arash Ash, Jesus J. Ballesteros, Aishwarya Balwani, Eleanor Batty, Ulrik Beierholm, Ari S. Benjamin, Upinder Bhalla, Gunnar Blohm, Joachim C. H. Blohm, Kathryn Bonnen, Marco Brigham, Bingni W. Brunton, John Butler, Brandon Caie, N Alex Cayco Gajic, Sharbatanu Chatterjee, Spyridon Chavlis, Ruidong Chen, You Cheng, H. M. Chow, Raymond Chua, Yunwei Dai, Isaac David, Eric E. J. Dewitt, Julien Denis, Alish Dipani, Arianna Dorschel, Jan Drugowitsch, Kshitij Dwivedi, Sean Escola, Haoxue Fan, Roozbeh Farhoodi, Yicheng Fei, Pierre-Étienne Fiquet, Lorenzo Fontolan, Jeremy Forest, Yuki Fujishima, Byron V. Galbraith, Mario Galdamez, Richard Gao, Julijana Gjorgjieva, Alexander Gonzalez, Qinglong Gu, Yueqi Guo, Ziyi Guo, Pankaj K. Gupta, Busra Tugce Gurbuz, Caroline Haimerl, Jordan B. Harrod, Alexandre Hyafil, Martin Irani, Daniel Jacobson, Michelle Johnson, Ilenna Simone Jones, Gili Karni, Robert E. Kass, Hyosub Edward Kim, Andreas M. Kist, Randal Koene, Konrad Kording, Matthew R. Krause, Arvind Kumar, Norma K. Kühn, Ray Lc, Matthew L. Laporte, Junseok Lee, Songting Li, Sikun Lin, Yang Lin, Shuze Liu, Tony Liu, Jesse A. Livezey, Linlin Lu, Jakob H. Macke, Kelly Mahaffy, A. Lucas Martins, Nicolás Martorell, Manolo Martínez, Marcelo G. Mattar, Jorge Aurelio Menendez, Kenneth D. Miller, Patrick J. Mineault, Nosratullah Mohammadi, Yalda Mohsenzadeh, Elenor Morgenroth, Taha Morshedzadeh, Alice Claudia Mosberger, Madhuvanthi Muliya, Marieke Mur, John D. Murray, Yashas Nd, Richard Naud, Prakriti Nayak, Anushka Oak, Itzel Olivos Castillo, Seyedmehdi Orouji, Jorge Otero-Millan, Marius Pachitariu, Biraj Pandey, Renato Paredes, Jesse Parent, Il Memming Park, Megan A. K. Peters, Xaq Pitkow, Panayiota Poirazi, Haroon Popal, Sandhya Prabhakaran, Tian Qiu, Srinidhi Ragunathan, Raul Rodriguez-Cruces, David Rolnick, Ashish Kumar Sahoo, Saeed Salehinajafabadi, Cristina Savin, Shreya Saxena, Paul Schrater, Karen Schroeder, Alice C. Schwarze, Madineh Sedigh-Sarvestani, K. Yuvaraj Sekhar, Reza Shadmehr, Maryam M. Shanechi, Siddhant Sharma, Eric Shea-Brown, Krishna V. Shenoy, Carolina L. Shimabukuro, Sergey Shuvaev, Man Ching Alison Sin, Maurice Smith, Nicholas A. Steinmetz, Karolina Stosio, Elizabeth Straley, Gabrielle Strandquist, Carsen Stringer, Rimjhim Tomar, Ngoc Tran, Sofia Triantafillou, Lawrence Udeigwe, Davide Valeriani, Vincent Valton, Maryam Vaziri-Pashkam, Peter Vincent, Gal Vishne, Pascal Wallisch, Peiyuan Wang, Claire Ward, Michael Waskom, Kunlin Wei, Anqi Wu, Zhengwei Wu, Brad Wyble, Lei Zhang, Daniel Zysman, Federico D’Oleire Uquillas, Tara Van Viegen Jan 2022

Neuromatch Academy: A 3-Week, Online Summer School In Computational Neuroscience, Bernard Marius 'T Hart, Titipat Achakulvisut, Ayoade Adeyemi, Athena Akrami, Bradly Alicea, Alicia Alonso-Andres, Diego Alzate-Correa, Arash Ash, Jesus J. Ballesteros, Aishwarya Balwani, Eleanor Batty, Ulrik Beierholm, Ari S. Benjamin, Upinder Bhalla, Gunnar Blohm, Joachim C. H. Blohm, Kathryn Bonnen, Marco Brigham, Bingni W. Brunton, John Butler, Brandon Caie, N Alex Cayco Gajic, Sharbatanu Chatterjee, Spyridon Chavlis, Ruidong Chen, You Cheng, H. M. Chow, Raymond Chua, Yunwei Dai, Isaac David, Eric E. J. Dewitt, Julien Denis, Alish Dipani, Arianna Dorschel, Jan Drugowitsch, Kshitij Dwivedi, Sean Escola, Haoxue Fan, Roozbeh Farhoodi, Yicheng Fei, Pierre-Étienne Fiquet, Lorenzo Fontolan, Jeremy Forest, Yuki Fujishima, Byron V. Galbraith, Mario Galdamez, Richard Gao, Julijana Gjorgjieva, Alexander Gonzalez, Qinglong Gu, Yueqi Guo, Ziyi Guo, Pankaj K. Gupta, Busra Tugce Gurbuz, Caroline Haimerl, Jordan B. Harrod, Alexandre Hyafil, Martin Irani, Daniel Jacobson, Michelle Johnson, Ilenna Simone Jones, Gili Karni, Robert E. Kass, Hyosub Edward Kim, Andreas M. Kist, Randal Koene, Konrad Kording, Matthew R. Krause, Arvind Kumar, Norma K. Kühn, Ray Lc, Matthew L. Laporte, Junseok Lee, Songting Li, Sikun Lin, Yang Lin, Shuze Liu, Tony Liu, Jesse A. Livezey, Linlin Lu, Jakob H. Macke, Kelly Mahaffy, A. Lucas Martins, Nicolás Martorell, Manolo Martínez, Marcelo G. Mattar, Jorge Aurelio Menendez, Kenneth D. Miller, Patrick J. Mineault, Nosratullah Mohammadi, Yalda Mohsenzadeh, Elenor Morgenroth, Taha Morshedzadeh, Alice Claudia Mosberger, Madhuvanthi Muliya, Marieke Mur, John D. Murray, Yashas Nd, Richard Naud, Prakriti Nayak, Anushka Oak, Itzel Olivos Castillo, Seyedmehdi Orouji, Jorge Otero-Millan, Marius Pachitariu, Biraj Pandey, Renato Paredes, Jesse Parent, Il Memming Park, Megan A. K. Peters, Xaq Pitkow, Panayiota Poirazi, Haroon Popal, Sandhya Prabhakaran, Tian Qiu, Srinidhi Ragunathan, Raul Rodriguez-Cruces, David Rolnick, Ashish Kumar Sahoo, Saeed Salehinajafabadi, Cristina Savin, Shreya Saxena, Paul Schrater, Karen Schroeder, Alice C. Schwarze, Madineh Sedigh-Sarvestani, K. Yuvaraj Sekhar, Reza Shadmehr, Maryam M. Shanechi, Siddhant Sharma, Eric Shea-Brown, Krishna V. Shenoy, Carolina L. Shimabukuro, Sergey Shuvaev, Man Ching Alison Sin, Maurice Smith, Nicholas A. Steinmetz, Karolina Stosio, Elizabeth Straley, Gabrielle Strandquist, Carsen Stringer, Rimjhim Tomar, Ngoc Tran, Sofia Triantafillou, Lawrence Udeigwe, Davide Valeriani, Vincent Valton, Maryam Vaziri-Pashkam, Peter Vincent, Gal Vishne, Pascal Wallisch, Peiyuan Wang, Claire Ward, Michael Waskom, Kunlin Wei, Anqi Wu, Zhengwei Wu, Brad Wyble, Lei Zhang, Daniel Zysman, Federico D’Oleire Uquillas, Tara Van Viegen

Articles

No abstract provided.


Demand Side Management Of Electric Vehicles In Smart Grids: A Survey On Strategies, Challenges, Modeling, And Optimization, Sarthak Mohanty, Subhasis Panda, Shubhranshu Mohan Parida, Pravat Kumar Rout, Binod Kumar Sahu, Mohit Bajaj, Hossam Zawbaa, Nallapaneni Manoj Kumar, Salah Kamel Jan 2022

Demand Side Management Of Electric Vehicles In Smart Grids: A Survey On Strategies, Challenges, Modeling, And Optimization, Sarthak Mohanty, Subhasis Panda, Shubhranshu Mohan Parida, Pravat Kumar Rout, Binod Kumar Sahu, Mohit Bajaj, Hossam Zawbaa, Nallapaneni Manoj Kumar, Salah Kamel

Articles

The shift of transportation technology from internal combustion engine (ICE) based vehicles to electricvehicles (EVs) in recent times due to their lower emissions, fuel costs, and greater efficiency hasbrought EV technology to the forefront of the electric power distribution systems due to theirability to interact with the grid through vehicle-to-grid (V2G) infrastructure. The greater adoptionof EVs presents an ideal use-case scenario of EVs acting as power dispatch, storage, and ancillaryservice-providing units. This EV aspect can be utilized more in the current smart grid (SG) scenarioby incorporating demand-side management (DSM) through EV integration. The integration of EVswith DSM techniques is hurdled …


Overarching Preventive Sympathetic Tripping Approach In Active Distribution Networks Without Telecommunication Platforms And Additional Protective Devices, Tahereh Dehghani Firouzabadi, Davoud Abootorabi Zarchi, Mohammadreza Mazid, Hadi Safdarkhani, Hamed Nafisi Jan 2022

Overarching Preventive Sympathetic Tripping Approach In Active Distribution Networks Without Telecommunication Platforms And Additional Protective Devices, Tahereh Dehghani Firouzabadi, Davoud Abootorabi Zarchi, Mohammadreza Mazid, Hadi Safdarkhani, Hamed Nafisi

Articles

Nowadays, distributed generation (DG) has made it possible to generate electricity close to the consumption site, resulting in improved efficiency, less environmental pollution, and higher economic profit. These advantages have led to increased penetration of DGs in the distribution system. Protective devices in a distribution system are set by considering the main substation as the only source for feeding short circuit current. However, with the increased influence of DGs as the second main source of short circuit current in distribution systems the short circuit level changes, which leads to false tripping of protective devices, including overcurrent relays. A sympathetic trip, …


Stealing Organs?, Benjamin J. Mcmichael Jan 2022

Stealing Organs?, Benjamin J. Mcmichael

Articles

Every nine minutes, a new person joins a waitlist for an organ transplant, and every day, seventeen people die waiting for an organ that will never come. Because the need for organ transplants far outstrips the number of available organs, the policies and rules governing organ allocation in the United States are critically important and highly contentious. Recently, proponents of a new allocation system one focused more on sharing organs across the nation instead of allocating organs primarily to local transplant candidates have gained ground. Bolstered by two separate lawsuits in the past five years, advocates of greater national sharing …


Drivers Of Environmental Degradation In Turkey: Designing An Sdg Framework Through Advanced Quantile Approaches, Tomiwa Sunday Adebayo, Ephraim Bonah Agyekum, Salah Kamel, Hossam Zawbaa, Mehmet Altuntaş Jan 2022

Drivers Of Environmental Degradation In Turkey: Designing An Sdg Framework Through Advanced Quantile Approaches, Tomiwa Sunday Adebayo, Ephraim Bonah Agyekum, Salah Kamel, Hossam Zawbaa, Mehmet Altuntaş

Articles

Turkey is a laggard in terms of the achievement of its Sustainable Development Goals (SDGs), and one of the primary issues it faces is environmental deterioration. Therefore, a policy-level reorientation may be needed to address this relevant issue. From this standpoint, this research assesses the impact of renewable energy (RE) use and financial development on the emissions of CO2 as well as the role of urbanization and agriculture, utilizing a dataset stretching between 1985 and 2019. By applying the innovative quantile-on-quantile regression (QQR) and non-parametric Granger causality in quantiles techniques, the study assesses the ways in which the quantiles of …


Adopting Scenario-Based Approach To Solve Optimal Reactive Power Dispatch Problem With Integration Of Wind And Solar Energy Using Improved Marine Predator Algorithm, Noor Habib Khan, Raheela Jamal, Mohamed Ebeed, Salah Kamel, Hamed Zeinoddini-Meymand, Hossam Zawbaa Jan 2022

Adopting Scenario-Based Approach To Solve Optimal Reactive Power Dispatch Problem With Integration Of Wind And Solar Energy Using Improved Marine Predator Algorithm, Noor Habib Khan, Raheela Jamal, Mohamed Ebeed, Salah Kamel, Hamed Zeinoddini-Meymand, Hossam Zawbaa

Articles

The penetration of renewable energy resources into electric power networks has been increased considerably to reduce the dependence of conventional energy resources, reducing the generation cost and greenhouse emissions. The wind and photovoltaic (PV) based systems are the most applied technologies in electrical systems compared to other technologies of renewable energy resources. However, there are some complications and challenges to incorporating these resources due to their stochastic nature, intermittency, and variability of output powers. Therefore, solving the optimal reactive power dispatch (ORPD) problem with considering the uncertainties of renewable energy resources is a challenging task. Application of the Marine Predators …


Automated Extraction Of Genes Associated With Antibiotic Resistance From The Biomedical Literature, Andre Brincat, Markus Hofmann Jan 2022

Automated Extraction Of Genes Associated With Antibiotic Resistance From The Biomedical Literature, Andre Brincat, Markus Hofmann

Articles

The detection of bacterial antibiotic resistance phenotypes is important when carrying out clinical decisions for patient treatment. Conventional phenotypic testing involves culturing bacteria which requires a significant amount of time and work. Whole-genome sequencing is emerging as a fast alternative to resistance prediction, by considering the presence/absence of certain genes. A lot of research has focused on determining which bacterial genes cause antibiotic resistance and efforts are being made to consolidate these facts in knowledge bases (KBs). KBs are usually manually curated by domain experts to be of the highest quality. However, this limits the pace at which new facts …


Power Management In Hybrid Anfis Pid Based Ac–Dc Microgrids With Eho Based Cost Optimized Droop Control Strategy, T. Narasimha Prasad, S. Devakirubakaran, S. Muthubalaji, S. Srinivasan, B. Karthikeyan, R. Palanisamy, Mohit Bajaj, Hossam Zawbaa, Salah Kamel Jan 2022

Power Management In Hybrid Anfis Pid Based Ac–Dc Microgrids With Eho Based Cost Optimized Droop Control Strategy, T. Narasimha Prasad, S. Devakirubakaran, S. Muthubalaji, S. Srinivasan, B. Karthikeyan, R. Palanisamy, Mohit Bajaj, Hossam Zawbaa, Salah Kamel

Articles

One of the most critical operations aspects is power management strategies for hybrid AC/DC microgrids. This work presented power management in hybrid AC–DC microgrids with a droop control strategy. At first, photovoltaic, Wind, and battery are used as the power sources, which supply the power with uncertainties. The AC and DC microgrids are controlled by an Adaptive neuro-fuzzy inference system (ANFIS) controller and Proportional Integral Derivative (PID) controller. Simultaneously we calculate the running cost for photovoltaic, Wind, and Battery. Moreover, an optimizer based on the elephant herding optimization algorithm is formulated to reduce the cost price. This method utilizes two …


Free Energies For Nonlinear Materials With Memory, John Murrough Golden Jan 2022

Free Energies For Nonlinear Materials With Memory, John Murrough Golden

Articles

An exploration of representations of free energies and associated rates of dissipation for a broad class of nonlinear viscoelastic materials is presented in this work. Also included are expressions for the stress functions and work functions derivable from such free energies. For simplicity, only the scalar case is considered. Certain standard formulae are generalized to include higher power terms.

It is shown that the correct initial procedure in this context is to specify the rate of dissipation as a positive semi-definite functional and then to determine the free energy from this, rather than the other way around, which would be …


Mathematical Analysis Of The Van Der Waals Equation, Emil Prodanov Jan 2022

Mathematical Analysis Of The Van Der Waals Equation, Emil Prodanov

Articles

The parametric cubic van der Waals polynomial $p V^3 - (R T + b p) V^2 + a V - a b$ is analysed mathematically and some new generic features (theoretically, for any substance) are revealed: the temperature range for applicability of the van der Waals equation, $T > a/(4Rb)$, and the isolation intervals, at any given temperature between $a/(4Rb)$ and the critical temperature $8a/(27Rb)$, of the three volumes on the isobar--isotherm: $3b/2 < V_A \le 3b$, $ 2b < V_B < 4b/(3 - \sqrt{5})$, and $3b < V_C < b + RT/p$. The unstable states of the van der Waals model have also been generically localized: they lie in an interval within the isolation interval of $V_B$. In the case of unique intersection point of an isotherm with an isobar, the isolation interval of this unique volume is also determined. A discussion on finding the volumes $V_{A, B, C}$, on the premise of Maxwell's hypothesis, is also presented.


Review Of Analytical Techniques For Arsenic Detection And Determination In Drinking Water, Abhijnan Bhat, Tony O'Hara, Furong Tian, Baljit Singh Dr. Jan 2022

Review Of Analytical Techniques For Arsenic Detection And Determination In Drinking Water, Abhijnan Bhat, Tony O'Hara, Furong Tian, Baljit Singh Dr.

Articles

Arsenic occurs in the natural environment in four oxidation states: As(V), As(III), As(0) and As(−III). The behavior of arsenic species changes depending on the biotic or abiotic conditions in water. In groundwater, arsenic is predominantly present as As(III) and As(V), with a minor amount of methyl and dimethyl arsenic compounds being reported. Global intake of As(III) and As(V) via drinking water and food has dramatically increased in recent years. The commonly used term inorganic arsenic includes both As(III) and As(V) species and constitutes the highest toxicological risk associated with arsenic in water compared to the organic arsenic species. Inorganic arsenic …


Trends In Biomedical Analysis Of Red Blood Cells – Raman Spectroscopy Against Other Spectroscopic, Microscopic And Classical Techniques, Jakub Dybas, Fatih Celal Alcicek, Aleksandra Wajda, Magdalena Kaczmarska, Anna Zimna, Katarzyna Bulat, Aneta Blat, Tetiana Stepanenko, Tasnim Mohaissen, Ewa Szczesny-Malysiak, David Perez-Guaita, Bayden R. Wood, Katarzyna Maria Marzec Jan 2022

Trends In Biomedical Analysis Of Red Blood Cells – Raman Spectroscopy Against Other Spectroscopic, Microscopic And Classical Techniques, Jakub Dybas, Fatih Celal Alcicek, Aleksandra Wajda, Magdalena Kaczmarska, Anna Zimna, Katarzyna Bulat, Aneta Blat, Tetiana Stepanenko, Tasnim Mohaissen, Ewa Szczesny-Malysiak, David Perez-Guaita, Bayden R. Wood, Katarzyna Maria Marzec

Articles

Application of modern and innovative spectroscopic and microscopic approaches to biomedical analysis opens new horizons and sheds new light on many unexplored scientific territories. In this review, we critically summarize up-to-date Raman-based methodologies for red blood cells (RBCs) analysis used in biology and medicine, and compare them with both classical, as well as other spectroscopic and microscopic approaches. The main emphasis is placed on the advantages, disadvantages and capabilities of each technique for detection of RBC deteriorations and RBC-related diseases. Although currently used classical techniques of medical analysts serve as a gold standard for clinicians in diagnosis of erythropathies, they …


Addictive Technology And Its Implications For Antitrust Enforcement, James Niels Rosenquist, Fiona M. Scott Morton, Samuel N. Weinstein Jan 2022

Addictive Technology And Its Implications For Antitrust Enforcement, James Niels Rosenquist, Fiona M. Scott Morton, Samuel N. Weinstein

Articles

The advent of mobile devices and digital media platforms in the past decade represents the biggest shock to cognition in human history. Robust medical evidence is emerging that digital media platforms are addictive and, when used in excess, harmful to users’ mental health. Other types of addictive products, like tobacco and prescription drugs, are heavily regulated to protect consumers. Currently, there is no regulatory structure protecting digital media users from these harms. Antitrust enforcement and regulation that lowers entry barriers could help consumers of social media by increasing competition. Economic theory tells us that more choice in digital media will …


Improving The Holographic Recording Characteristics Of A Water-Resistant Photosensitive Sol–Gel For Use In Volume Holographic Optical Elements, Brian Rogers, Tatsiana Mikulchyk, Mohamed Oubaha, Dervil Cody, Suzanne Martin, Izabela Naydenova Jan 2022

Improving The Holographic Recording Characteristics Of A Water-Resistant Photosensitive Sol–Gel For Use In Volume Holographic Optical Elements, Brian Rogers, Tatsiana Mikulchyk, Mohamed Oubaha, Dervil Cody, Suzanne Martin, Izabela Naydenova

Articles

Continual improvements to holographic recording materials make the development of volume holographic optical elements increasingly more attainable for applications where highly efficient, lightweight diffractive optical elements can replace conventional optics. A fast-curing, water resistant photosensitive sol–gel capable of volume holographic recording has recently drawn attention for its extreme environmental and physical robustness, in particular its water/moisture and scratch resistance. However, to date, the refractive index modulation has been limited. While water-resistant properties are invaluable in the face of the weathering which many practical systems for outdoor applications will endure, high refractive index modulation is also important in order to facilitate …


Federalism By Deception: The Implied Limits On Congressional Power, Bryan K. Fair Jan 2022

Federalism By Deception: The Implied Limits On Congressional Power, Bryan K. Fair

Articles

The purpose of this Article is to lay bare federalism by deception and the theory of implied limits on federal power. Other scholars have recently noted the rise of anti-federalist viewpoints in modern cases. I go a step further to demonstrate how Supreme Court Justices have embraced anti-federal ideology, but have cited Federalist sources, including Marshall, to announce unenumerated limits on federal legislative power.


What Is Consumer Protection For?, Luke Herrine Jan 2022

What Is Consumer Protection For?, Luke Herrine

Articles

When law and economics barreled its way into consumer protection scholarship two score years ago, it brought with it the consumer sovereignty framework: an approach to analysis in which actual markets are compared to an ideal market in which consumers optimize exogenous welfare functions by choosing between optimally competitive sellers. Even after two decades of behavioralist critique and even with increasingly critical perspectives taking root since the Global Financial Crisis, this consumer sovereignty ideal continues to serve as both a descriptive and normative baseline for consumer protection scholarship.

This Article argues that it is time to reconsider the consumer sovereignty …


Bringing Predictability To The Chaos Of Punitive Damages, Benjamin Mcmichael, W. Kip Viscusi Jan 2022

Bringing Predictability To The Chaos Of Punitive Damages, Benjamin Mcmichael, W. Kip Viscusi

Articles

Punitive damages remain unique in the American legal system. Awarded in the civil context with none of the protections offered in criminal law, courts levy punitive damages to punish and deter. The Supreme Court of the United States has clearly stated that courts may only seek to achieve these two goals when imposing punitive damages. A closer reading of the Court's punitive damages jurisprudence, however, reveals another goal that has largely been ignored: predictability. Unlike punishment and deterrence, predictability is not a purpose for which to award punitive damages. Instead, the Court requires that, when awarded, the level of punitive …


Contracts In The Age Of Smart Readers, Yonathan A. Arbel, Becher, Shmuel I. Jan 2022

Contracts In The Age Of Smart Readers, Yonathan A. Arbel, Becher, Shmuel I.

Articles

No abstract provided.


Exclusion Cycles: Reinforcing Disparities In Medicine, Ana Bracic, Shawneequa L. Callier, Nicholson Price Jan 2022

Exclusion Cycles: Reinforcing Disparities In Medicine, Ana Bracic, Shawneequa L. Callier, Nicholson Price

Articles

Minoritized populations face exclusion across contexts from politics to welfare to medicine. In medicine, exclusion manifests in substantial disparities in practice and in outcome. While these disparities arise from many sources, the interaction between institutions, dominant-group behaviors, and minoritized responses shape the overall pattern and are key to improving it. We apply the theory of exclusion cycles to medical practice, the collection of medical big data, and the development of artificial intelligence in medicine. These cycles are both self-reinforcing and other-reinforcing, leading to dismayingly persistent exclusion. The interactions between such cycles offer lessons and prescriptions for effective policy.


Regulating For Energy Justice, Alexandra B. Klass, Gabriel Chan Jan 2022

Regulating For Energy Justice, Alexandra B. Klass, Gabriel Chan

Articles

In this Article, we explore and critique the foundational norms that shape federal and state energy regulation and suggest pathways for reform that can incorporate principles of “energy justice.” These energy justice principles—developed in academic scholarship and social movements—include the equitable distribution of costs and benefits of the energy system, equitable participation and representation in energy decision making, and restorative justice for structurally marginalized groups.

While new legislation, particularly at the state level, is critical to the effort to advance energy justice, our focus here is on regulators’ ability to implement reforms now using their existing authority to advance the …


Copper(Ii) And Silver(I)‑1,10‑Phenanthroline‑5,6‑Dione Complexes Interact With Double‑Stranded Dna: Further Evidence Of Their Apparent Multi‑Modal Activity Towards Pseudomonas Aeruginosa, Anna Clara Milesi Galdino, Lívia Viganor, Matheus Mendonça Pereira, Michael Devereux, Malachy Mccann, Marta Helena Branquinha, Zara Molphy, Sinéad O'Carroll, Conor Bain, Georgia Menounou, Andrew Kellett, André Luis Souza Dos Santos Jan 2022

Copper(Ii) And Silver(I)‑1,10‑Phenanthroline‑5,6‑Dione Complexes Interact With Double‑Stranded Dna: Further Evidence Of Their Apparent Multi‑Modal Activity Towards Pseudomonas Aeruginosa, Anna Clara Milesi Galdino, Lívia Viganor, Matheus Mendonça Pereira, Michael Devereux, Malachy Mccann, Marta Helena Branquinha, Zara Molphy, Sinéad O'Carroll, Conor Bain, Georgia Menounou, Andrew Kellett, André Luis Souza Dos Santos

Articles

Tackling microbial resistance requires continuous efforts for the development of new molecules with novel mechanisms of action and potent antimicrobial activity. Our group has previously identified metal-based compounds, [Ag(1,10-phenanthroline-5,6-dione)2]ClO4 (Ag-phendione) and [Cu(1,10-phenanthroline-5,6-dione)3](ClO4)2.4H2O (Cu-phendione), with efficient antimicrobial action against multidrug-resistant species. Herein, we investigated the ability of Ag-phendione and Cu-phendione to bind with double-stranded DNA using a combination of in silico and in vitro approaches. Molecular docking revealed that both phendione derivatives can interact with the DNA by hydrogen bonding, hydrophobic and electrostatic interactions. Cu-phendione exhibited the highest binding affinity to either major (− 7.9 kcal/mol) or minor (− 7.2 kcal/mol) …


Bodipy–Pyrene Donor–Acceptor Sensitizers For Triplet–Triplet Annihilation Upconversion: The Impact Of The Bodipy-Core On Upconversion Efficiency, Natalia Kiseleva, Mikhail Filatov, Jan C. Fischer, Milian Kaiser, Marius Jakoby, Dimitry Busko, Ian A. Howard, Bryce Richards, Andrey Turshatov Jan 2022

Bodipy–Pyrene Donor–Acceptor Sensitizers For Triplet–Triplet Annihilation Upconversion: The Impact Of The Bodipy-Core On Upconversion Efficiency, Natalia Kiseleva, Mikhail Filatov, Jan C. Fischer, Milian Kaiser, Marius Jakoby, Dimitry Busko, Ian A. Howard, Bryce Richards, Andrey Turshatov

Articles

Triplet–triplet annihilation upconversion (TTA-UC) is an important type of optical process with applications in biophotonics, solar energy harvesting and photochemistry. In most of the TTA-UC systems, the formation of triplet excited states takes place via spin–orbital interactions promoted by heavy atoms. Given the crucial role of heavy atoms (especially noble metals, such as Pd and Pt) in promoting intersystem crossing (ISC) and, therefore, in production of UC luminescence, the feasibility of using more readily available and inexpensive sensitizers without heavy atoms remains a challenge. Here, we investigated sensitization of TTA-UC using BODIPY–pyrene heavy-atom-free donor–acceptor dyads with different numbers of alkyl …