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Modulation Of Radiation Responses By Pre-Exposure To Irradiated Cell Conditioned Medium, Paula Maguire, Carmel Mothersill, B. Mcclean, C. Seymour, Fiona Lyng Jan 2007

Modulation Of Radiation Responses By Pre-Exposure To Irradiated Cell Conditioned Medium, Paula Maguire, Carmel Mothersill, B. Mcclean, C. Seymour, Fiona Lyng

Articles

The aim of this study was to investigate whether exposure of HPV-G cells to irradiated cell conditioned medium (ICCM) could induce an adaptive response if the cells were subsequently challenged with a higher ICCM dose. Clonogenic survival and major steps in the cascade leading to apoptosis, such as calcium influx and loss of mitochondrial membrane potential, were examined to determine whether these events could be modified by giving a priming dose of ICCM before the challenge dose. Clonogenic survival data indicated an ICCMinduced adaptive response in HPV-G cells ‘‘primed’’ with 5 mGy or 0.5 Gy ICCM for 24 h and …


Bringing Deference Back (But For How Long?), Stephen M. Johnson Jan 2007

Bringing Deference Back (But For How Long?), Stephen M. Johnson

Articles

For most of the past decade, the Supreme Court seemed to be gradually eroding the deference accorded to administrative agencies. In Christensen v. Harris County and United States v. Mead Corp. the Court refused to accord Chevron deference to agencies' interpretations of statutes when the agencies adopted those interpretations through informal procedures. The trend appeared to continue when the Court refused to accord Chevron deference to tobacco regulations adopted by the Food and Drug Administration in FDA v. Brown & Williamson Tobacco Corp. or to controlled substance regulations adopted by the Attorney General in Gonzales v. Oregon. In addition, …


Policy Formulation Versus Policy Implementation Under The Magnuson-Stevens Fishery Conservation And Management Act: Crab Rationalization, Richard Henry Seamon Jan 2007

Policy Formulation Versus Policy Implementation Under The Magnuson-Stevens Fishery Conservation And Management Act: Crab Rationalization, Richard Henry Seamon

Articles

The Magnuson-Stevens Fishery Conservation and Management Act (MSA) governs management of fisheries located three to 200 miles off the coast of the United States. The MSA is unique in administrative law in that it devolves policy formulation to eight Regional Fishery Management Councils rather than to a federal agency. That agency, the National Marine Fisheries Service (NMFS), is relegated primarily to developing regulations that implement the councils' policies. NMFS can review the councils' policies only to ensure that they are consistent with existing laws. NMFS has no authority to revise policy to suit its own preferences, or to write regulations …


What Happened On Deliberation Day, Cass R. Sunstein, Reid Hastie, David Schkade Jan 2007

What Happened On Deliberation Day, Cass R. Sunstein, Reid Hastie, David Schkade

Articles

What are the effects of deliberation about legal and political issues by like-minded people? This Essay reports the results of an experimental investigation involving sixty-three citizens in Colorado. Groups from Boulder, a predominantly liberal city, met to discuss global warming, affirmative action, and civil unions for same-sex couples. Groups from Colorado Springs, a predominately conservative city, discussed the same issues. The major effect of deliberation was to make group members more extreme in their views than they were before they started to talk. Liberals became more liberal on all three issues; conservatives became more conservative. As a result of intragroup …


On Discounting Regulatory Benefits: Risk, Money, And Intergenerational Equity, Arden Rowell, Cass R. Sunstein Jan 2007

On Discounting Regulatory Benefits: Risk, Money, And Intergenerational Equity, Arden Rowell, Cass R. Sunstein

Articles

There is an elaborate debate over the practice of "discounting" regulatory benefits, such as environmental improvements and decreased risks to health and life, when those benefits will not be enjoyed until some future date. Economists tend to think that, as a general rule, such benefits should be discounted in the same way as money; many philosophers and lawyers doubt that conclusion on empirical and normative grounds. Both sides frequently neglect a simple point: if regulators are interested in how people currently value risks that will not come to fruition for a significant time, they can use people's current willingness to …


On The Divergent American Reactions To Terrorism And Climate Change, Cass R. Sunstein Jan 2007

On The Divergent American Reactions To Terrorism And Climate Change, Cass R. Sunstein

Articles

Two of the most important sources of catastrophic risk are terrorism and climate change. The United States has responded aggressively to the risk of terrorism while doing very little about the risk of climate change. For the United States alone, the cost of the Iraq War is in excess of the anticipated cost of the Kyoto Protocol. The divergence presents a puzzle; it also raises more general questions about both risk perception and the public demand for legislation. The best explanation for the divergence emphasizes bounded rationality. Americans believe that aggressive steps to reduce the risk of terrorism promise to …


Willingness To Pay Vs. Welfare, Cass R. Sunstein Jan 2007

Willingness To Pay Vs. Welfare, Cass R. Sunstein

Articles

No abstract provided.


The Case For For-Profit Charities, Anup Malani, Eric A. Posner Jan 2007

The Case For For-Profit Charities, Anup Malani, Eric A. Posner

Articles

No abstract provided.


Deference, Delegation, And Immigration Law, Adam B. Cox Jan 2007

Deference, Delegation, And Immigration Law, Adam B. Cox

Articles

No abstract provided.


Restoring The Right Constitution? (Reviewing Randy Barnett, Restoring The Lost Constitution: The Presumption Of Liberty (2004)), Eduardo Peñalver Jan 2007

Restoring The Right Constitution? (Reviewing Randy Barnett, Restoring The Lost Constitution: The Presumption Of Liberty (2004)), Eduardo Peñalver

Articles

No abstract provided.


In Memoriam: Bernard D. Meltzer (1914-2007), Saul Levmore Jan 2007

In Memoriam: Bernard D. Meltzer (1914-2007), Saul Levmore

Articles

No abstract provided.


In Defense Of Prometheus: Some Ethical, Economic, And Regulatory Issues Of Sports Doping, Richard A. Posner Jan 2007

In Defense Of Prometheus: Some Ethical, Economic, And Regulatory Issues Of Sports Doping, Richard A. Posner

Articles

No abstract provided.


How To Create - Or Destroy - Wealth In Real Property, Richard A. Epstein Jan 2007

How To Create - Or Destroy - Wealth In Real Property, Richard A. Epstein

Articles

No abstract provided.


Coniston Corp V. Village Of Hoffman Hills: How To Make Procedural Due Process Disappear, Richard A. Epstein Jan 2007

Coniston Corp V. Village Of Hoffman Hills: How To Make Procedural Due Process Disappear, Richard A. Epstein

Articles

No abstract provided.


Agencies Should Ignore Distant-Future Generations, Eric A. Posner Jan 2007

Agencies Should Ignore Distant-Future Generations, Eric A. Posner

Articles

No abstract provided.


Conflicts Of Interest In Health Care: Who Guards The Guardians?, Richard A. Epstein Jan 2007

Conflicts Of Interest In Health Care: Who Guards The Guardians?, Richard A. Epstein

Articles

No abstract provided.


''Don't Try This At Home': Posner As Political Economist, Lior Strahilevitz Jan 2007

''Don't Try This At Home': Posner As Political Economist, Lior Strahilevitz

Articles

No abstract provided.


From Penn Central To Lingle: The Long Backwards Road, Richard A. Epstein Jan 2007

From Penn Central To Lingle: The Long Backwards Road, Richard A. Epstein

Articles

No abstract provided.


Prediction Markets For Corporate Governance, M. Todd Henderson, Michael Abramowicz Jan 2007

Prediction Markets For Corporate Governance, M. Todd Henderson, Michael Abramowicz

Articles

No abstract provided.


Property And Half-Torts, Lee Anne Fennell Jan 2007

Property And Half-Torts, Lee Anne Fennell

Articles

The idea that a tort can be split analytically into two parts -risk and harm- underlies a great deal of torts scholarship. Yet the notion has been all but ignored by property scholars employing Calabresi and Melamed's famous entitlement framework. Thus, i


Exclusionary Rule And Causation: Hudson V. Michigan And Its Ancestors, The, Albert W. Alschuler Jan 2007

Exclusionary Rule And Causation: Hudson V. Michigan And Its Ancestors, The, Albert W. Alschuler

Articles

In Hudson v. Michigan, the Supreme Court held that evidence need not be excluded despite the fact that the police had violated the Fourth Amendment by failing to knock and announce their presence before conducting a search. The Court said that the constitutional violation was not a but-for cause of the seizure; the police would have obtained the evidence even if they had knocked. Hudson's analysis threatens to withdraw the exclusionary remedy whenever the police have conducted a search in an unconstitutional manner-most notably, when they have failed to obtain a warrant before searching. The Court's decision is likely to …


The Second-Order Structure Of Immigration Law, Adam B. Cox, Eric A. Posner Jan 2007

The Second-Order Structure Of Immigration Law, Adam B. Cox, Eric A. Posner

Articles

Immigration law concerns both first-order issues about the number and types of immigrants who should be admitted into a country and second-order design issues concerning the legal rules and institutions that are used to implement those first-order policy goals. The literature has focused on the first set of issues and largely neglected the second. In fact, many current controversies concern the design issues. This Article addresses the second-order dimension and argues that a central design choice all states face is whether to evaluate potential immigrants on the basis of pre-entry characteristics (the ex ante approach) or post-entry conduct (the ex …


The Neoclassical Economics Of Consumer Contracts, Richard A. Epstein Jan 2007

The Neoclassical Economics Of Consumer Contracts, Richard A. Epstein

Articles

No abstract provided.


Introduction To The Italian Edition Of Overdose, Richard A. Epstein Jan 2007

Introduction To The Italian Edition Of Overdose, Richard A. Epstein

Articles

No abstract provided.


The Erosion Of Individual Autonomy In Medical Decisionmaking: Of The Fda And Irbs, Richard A. Epstein Jan 2007

The Erosion Of Individual Autonomy In Medical Decisionmaking: Of The Fda And Irbs, Richard A. Epstein

Articles

No abstract provided.


Climate Change And International Human Rights Litigation: A Critical Appraisal, Eric A. Posner Jan 2007

Climate Change And International Human Rights Litigation: A Critical Appraisal, Eric A. Posner

Articles

No abstract provided.


Paretian Intergenerational Discounting, David A. Weisbach, Dexter Samida Jan 2007

Paretian Intergenerational Discounting, David A. Weisbach, Dexter Samida

Articles

This paper argues that discounting costs and benefits of projects for the opportunity costs of capital Pareto dominates decision criteria that do not discount. It considers and rejects several objections to the Pareto dominance argument, including the problem of making compensating transfers for the costs and benefits of projects and whether taking opportunity costs into account is different than discounting. It also argues that discounting future costs and benefits of projects does not undervalue future generations.


Introduction To Symposium On Immigration Reform: Balancing Enforcement And Integration, Aziz Huq Jan 2007

Introduction To Symposium On Immigration Reform: Balancing Enforcement And Integration, Aziz Huq

Articles

No abstract provided.


Defanging Irbs: Replacing Coercion With Information, Richard A. Epstein Jan 2007

Defanging Irbs: Replacing Coercion With Information, Richard A. Epstein

Articles

No abstract provided.


Use Of Statistical Evidence To Address Police Supervisory And Disciplinary Practices: The Chicago Police Department's Broken System, Craig B. Futterman, H. Melissa Mather, Melanie Miles Jan 2007

Use Of Statistical Evidence To Address Police Supervisory And Disciplinary Practices: The Chicago Police Department's Broken System, Craig B. Futterman, H. Melissa Mather, Melanie Miles

Articles

No abstract provided.