Digital Commons Network^™

Microencapsulated Ascorbic Acid: Development, Characterization, And Release Profile In Simulated Gastrointestinal Fluids, Michele Cristina Rodrigues Da Cruz, Camila Augusto Perussello, Maria Lúcia Masson

Articles

The aim of this study was to produce ascorbic acid (AA) microcapsules by complex coacervation, characterize them, and evaluate the release profile in simulated gastrointestinal fluids. The microcapsules were made of gelatin and pectin at concentrations of 1.0, 2.0, and 3.0%. The coacervated microcapsules were assessed for morphology (by optical microscopy and scanning electron microscopy), water activity (Aw), hygroscopicity, solubility, encapsulation efficiency (EE), thermal behavior, and AA release profile. The AA microcapsules were characterized by low solubility, low hygroscopicity, high thermal stability, and low diameter (<10 μm), with EE ranging from 23.7 to 94.3%. The release profile was faster in gastric fluid (pH 1.8) than in intestinal fluid (pH 6.8). The sample containing 2.0% of wall material and 50% (w/w) of the simple emulsion (core) had the highest EE and the best in vitro release profile, with release of only 68% of AA in 120 min in the gastric fluid.

Practical applications Ascorbic acid (AA) is widely used in the food industry as an …

Development Of A Hierarchical Model For Predicting Microbiological Contamination Of Private Groundwater Supplies In A Geologically Heterogeneous Region, Jean O'Dwyer, Paul Hynds, Kenneth Byrne, Michael Ryan, Catherine Adley

Articles

Private groundwater sources in the Republic of Ireland provide drinking water to an estimated 750,000 people or 16% of the national population. Consumers of untreated groundwater are at increased risk of infection from pathogenic microorganisms. However, given the volume of private wells in operation, remediation or even quantification of public risk is both costly and time consuming. In this study, a hierarchical logistic regression model was developed to ‘predict’ contamination with E. coli based on the results of groundwater quality analyses of private wells (n = 132) during the period of September 2011 to November 2012. Assessment of potential microbial …

Simultaneous Measurement Of Displacement And Temperature Based On Baloon - Shaped Bent Smf Structure Incorporating An Lpg, Ke Tian, Wenlei Yang, Gerald Farrell, Elfed Lewis, Xianfan Wang, Pengfei Wang

Articles

Abstract—A novel optical fibre sensor based on a balloon-shaped bent single-mode (BSBS) fibre structure incorporating a long-period grating (LPG) for simultaneous measurement of displacement and temperature is described and experimentally demonstrated. The sensor is fabricated by splicing a BSBS fibre structure formed Mach-Zehnder interferometer (MZI) with an LPG. Due to the interference dip which is formed by the BSBS fibre structure is sensitive to external displacement and temperature variation, while that formed by LPG only depends on temperature, displacement and temperature therefore can be unambiguously and simultaneously measured by this sensor. Experimental results show that this sensor offers a high …

A Comprehensive Experimental Study Of Whispering Gallery Modes In A Cylindrical Micro-Resonator Excited By A Tilted Fiber Taper, Vishnu Kavungal, Gerald Farrell, Qiang Wu, Arun Mallik, Yuliya Semenova

Articles

Whispering gallery modes (WGMs) excitation in a cylindrical microresonator formed by a section of silica optical fiber has been studied. Evanescent light coupling into the microresonator is realized using a tapered optical fiber, fabricated by a microheater brushing technique. Several types of silica fibers with different diameters are studied as microresonators, and the influence of the resonator's diameter on the excitation of WGMs is investigated. The excitation of WGMs in a cylindrical fiber resonator were studied with changes to the tilt angle between the microcylinder and the fiber taper in the range of angles from a perpendicular position (0 degrees) …

Nurturing ‘Buds Of Development’: From Outcomes To Opportunities In Early Childhood Practice, Noirin Hayes, Katarina Filipovic

Articles

The current future-focused, outcomes driven early childhood policy climate presents a danger that early years pedagogy will lose sight of the ‘present’ child. Increasingly policy support for early childhood education is built around an emphasis on preparing children for school and positioning it as a key element in enhancing society through preparing future citizens to become productive members of society. The measurable outcomes discourse, in emphasising product, renders invisible the critical contribution of the processes of everyday practice to children’s development. To challenge and counteract the strong outcome discourse early years professionals must have confidence in their pedagogy. However, research …

Public Goods And Public Policy: What Is Public Good, And Who And What Decides?, Ellen Hazelkorn, Andrew Gibson

Articles

Higher education is usually seen as serving the public good, especially when funded directly by the state, and because of the ‘social benefit efficiency gains and potential equity effects on opportunity and reduced inequality’ (McMahon, 2009, p. 255). Calhoun (2006, p. 19) argues that public support for higher education is only given and maintained according to its capacity, capability, and willingness, to ‘educate citizens in general, to share knowledge, to distribute it as widely as possible in accord with publically articulated purposes’.

Informing Quality In Emergency Care: Understanding Patient Experiences, Esmat Swallmeh, Vivienne Byers, Amr Arisha

Articles

Purpose: Assessing performance and quality in healthcare organisations is moving from focussing solely on clinical care measurement to considering the patient experience as critical. Much patient experience research is quantitative and survey based. The purpose of this paper is to report a qualitative study gathering in-depth data in an emergency department (ED).

Design/methodology/approach: The authors used empirical data from seven focus groups to understand patient experience as participants progressed through a major teaching hospital in an Ireland ED. A convenience sampling technique was used, and 42 participants were invited to share their perceptions and outline key factors affecting their journey. …

Contesting Early Childhood Professional Identities: A Cross-National Discussion, Sonja Arndt, Mathias Urban, Colette Murray, Kylie Smith, Beth Swadener, Tomas Ellegaard

Articles

In this collective article, the authors explore constructions of early childhood practitioners and how they disconnect and reconnect in a global neo-liberal education policy context. The contributions to the conversation provide windows into shifting professional identities across five national contexts: New Zealand, the USA, Ireland, Australia and Denmark. The authors ask who benefits from the notion of distinct professional identities, linked to early childhood education as locally and culturally embedded practice. They conceptualize teachers’ shifting subjectivities, drawing on Kristeva’s philosophical conception of identity as constantly in construction, open and evolving. Arguments for the urgency to counter the global uniformity machine, …

Lessons From The Global Financial Crisis–The Case Of Mainland China And Hong Kong, Lucia Morales, Bernadette Andreosso-O’Callaghan

Articles

The analysis of the intertwined reactions of Hong Kong and Mainland China to the 2008 Global Financial Crisis is considered in this study through the lenses of their stock markets. The GARCH-based analysis of stock market performance over the period December 2011–December 2014 shows that trade and equity sectors were the sectors most affected by the global recession; volatility was prevalent on the Shanghai stock market, whereas volatility persistence characterised the Hong Kong stock market. The results also show that the two stock markets recovered quite quickly. Tight controls applied by the financial authorities helped ensure some stability during the …

It's Not What You Do Its The Way That You Do It: The Influence Of Obesity On The Speed And Accuracy Of A Discrete Aiming Task, David Gaul, Laure Fernandez, Johann Issartel

Articles

The ability to control speed and accuracy of goal directed aiming tasks underpins many activities of daily living. Recent evidence has begun to suggest that obesity can affect the control of movement. This study evaluated perceptual motor control of 183 normal weight, overweight, and obese participants using a discrete Fitts’ task on a digital tablet. In addition, we manipulated tablet orientation to determine whether tablet orientation influences task difficulty with the view to increase the task’s constraints. Our study found that the traditional relationship between target distance and target width hold true for each of the three weight groups in …

Belonging At Itb: The Use Of Photovoice Methodology (Pvm) To Investigate Inclusion And Exclusion At Itb Based On Ethnicity And Nationality From A Student Perspective, Fionnuala Darby

Articles

The aim of this research is to sensitise readers to issues of inclusion and exclusion on campus at ITB in order to deepen our capacity to empathise with our students in a meaningful, accessible and evocative way in relation to ethnicity and/or nationality. Using Photovoice Methodology (PVM), the objective is to investigate the use of space and place that students occupy on campus. The outcomes of the research through images and text reveal surroundings on campus that students find inclusive and exclusive. The paper begins with a review of the literature salient to the topic. Then follows a description of …

Glaucoma Referral Refinement In Ireland: Managing The Sensitivity-Specificity Paradox In Optometric Practice, Catriona Barrett, O'Brien Colm, James Loughman

Articles

Purpose: Glaucoma referral refinement (GRR) has pr ven a successful demand management strategy for glaucoma suspect cases in the United Kingdom (UK). A GRR clinic was established in Dublin, Ireland to investigate the clinical viability of this pathway outside the UK's National Health Service (NHS) structures, and away from the influence of National Institute for Clinical Excellence (NICE) guidance.

Expanding The Traditional Role Of Optometry: Current Practice Patterns And Attitudes To Enhanced Glaucoma Services In Ireland, Catriona Barrett, James Loughman

Articles

Purpose: To investigate current diagnostic equipment availability and usage for glaucoma casefinding within community optometric practice, and to explore optometrists’ attitudes towards an enhanced scope of clinical practice. Methods: An anonymous survey was developed, validated, and distributed to all optometrists in Ireland. Results: 199 optometrists (27% of registrants) responded to the survey. 87% had access to the traditional triad of tests necessary to conduct adequate glaucoma case finding. Standard automated perimetry was the most commonly absent (13%) of the three essential screening tests. 64% of respondents indicated that monocular direct ophthalmoscopy was their first choice technique for fundus examination. 47% …

Nutritional Supplementation In The Treatment Of Glaucoma: A Systematic Review, Ekaterina Loskutova, Colm O’Brien, Igor Loskutov, James Loughman

Articles

Current treatment strategies for glaucoma are limited to halting disease progression and do not restore lost visual function. Intraocular pressure is the main risk factor for glaucoma, and intraocular pressure–lowering treatment remains the mainstay of glaucoma treatment, but even successful intraocular pressure reduction does not stop the progression of glaucoma in all patients. We review the literature to determine whether nutritional interventions intended to prevent or delay the progression of glaucoma could prove to be a valuable addition to the mainstay of glaucoma therapy. A total of 33 intervention trials were included in this review, including 21 randomized controlled …

Allen Carr’S Easyway To Stop Smoking - A Randomised Clinical Trial, Luke Clancy, Sheila Keogan, Shasha Li

Articles

Objective To determine if Allen Carr’s Easyway to Stop Smoking (AC) was superior to Quit. ie in a randomised clinical trial (RCT). Setting Single centre, open RCT, general population

Raman Spectroscopic Analysis Of High Molecular Weight Proteins In Solution: Considerations For Sample Analysis And Data Pre-Processing, Drishya Parachalil, Brenda B. Brankin, Jennifer Mcintyre, Hugh Byrne

Articles

This study explores the potential of Raman spectroscopy, coupled with multivariate regression techniques and a protein separation technique (ion exchange chromatography), to quantitatively monitor diagnostically relevant changes in high molecular weight proteins in liquid plasma. Measurement protocols to detect the imbalances in plasma proteins as an indicator of various diseases using Raman spectroscopy are optimised, such that strategic clinical applications for early stage disease diagnostics can be evaluated. In a simulated plasma protein mixture, concentrations of two proteins of identified diagnostic potential (albumin and fibrinogen) were systematically varied within physiologically relevant ranges. Scattering from the poorly soluble fibrinogen fraction is …

Tradition And Novelty: Food Representations In Irish Women’S Magazines 1922–73, Marzena Keating, Máirtín Mac Con Iomaire

Articles

Based on a qualitative content analysis of selected Irish women’s magazines, this paper provides a brief overview of Irish food culture from 1922 to 1973. It illustrates how selected texts from women’s magazines, mainly recipes, food columns, practical suggestions for cooking and housekeeping, as well as articles on food topics mirrored social, cultural, economic, and religious characteristics of a particular period. The paper discusses various culinary trends apparent in the content and style of cookery pages focusing on a paired category of novelty and tradition adapted from the quantitative research conducted by Alan Warde.

Introduction To Laser Induced Breakdown Spectroscopy Imaging In Food: Salt Diffusion In Meat, Yash Dixit, Carl Sullivan, Patrick J. Cullen

Articles

This study illustrates the ability of laser induced breakdown spectroscopy (LIBS) to detect and map 22 minerals in food. A LIBS system was used to spatially collect spectra of beef samples. Samples were 23 brined in a 6% salt solution for 2h and 24h along with a control sample. Samples were measured by 24 scanning the cross-section of each sample in a 90 X 90 square grid. Sodium (Na) distribution images 25 with respect to emission peak at 589.05 nm were generated after pre-processing the spectral data which 26 directly corresponds to salt levels. As expected, the control sample showed …

Nano-Strategies To Fight Multidrug Resistant Bacteria—“A Battle Of The Titans", Pedro V. Baptista, Matthew P. Mccusker, Andreia Carvalho, Daniela A. Ferreira, Niamh M. Mohan, Marta Martins, Alexandra R. Fernandez

Articles

Infectious diseases remain one of the leading causes of morbidity and mortality worldwide. The WHO and CDC have expressed serious concern regarding the continued increase in the development of multidrug resistance among bacteria. Therefore, the antibiotic resistance crisis is one of the most pressing issues in global public health. Associated with the rise in antibiotic resistance is the lack of new antimicrobials. This has triggered initiatives worldwide to develop novel and more effective antimicrobial compounds as well as to develop novel delivery and targeting strategies. Bacteria have developed many ways by which they become resistant to antimicrobials. Among those are …

Unprecedented In Vitro Antitubercular Activitiy Of Manganese(Ii) Complexes Containing 1,10- Phenanthroline And Dicarboxylate Ligands: Increased Activity, Superior Selectivity, And Lower Toxicity In Comparison To Their Copper(Ii) Analogs, Pauraic Mccarron, Malachy Mccann, Michael Devereux, Kevin Kavanagh, Ciaran M. Skerry, Petros C. Karakousis, Ana Carolina Aor, Thaís P. Mello, Dos Santos, André Luis Souza Dos Santos, André Luis Souza, Débora Leite Campos, Fernando R. Pavan

Articles

Mycobacterium tuberculosis is the etiologic agent of tuberculosis. The demand for new chemotherapeutics with unique mechanisms of action to treat (multi)resistant strains is an urgent need. The objective of this work was to test the effect of manganese(II) and copper(II) phenanthroline/dicarboxylate complexes against M. tuberculosis. The water-soluble Mn(II) complexes, [Mn2(oda)(phen)4(H2O)2][Mn2(oda)(phen)4(oda)2]·4H2O (1) and ([Mn(3,6,9-tdda)(phen)2]·3H2O·EtOH)n (3) (odaH2 = octanedioic acid, phen = 1,10-phenanthroline, tddaH2 = 3,6,9-trioxaundecanedioic acid), and water-insoluble complexes, [Mn(ph)(phen)(H2O)2] (5), [Mn(ph)(phen)2(H2O)]·4H2O (6), [Mn2(isoph)2(phen)3]·4H2O (7), ([Mn(phen)2(H2O)2])2(isoph)2(phen)·12H2O (8) and [Mn(tereph)(phen)2]·5H2O (9) (phH2 = phthalic acid, isophH2 = isophthalic acid, terephH2 = terephthalic acid), robustly inhibited the viability of M. tuberculosis strains, H37Rv …

Quality Of Fresh And Stored Mares’ Milk, Grażyna Czyżak-Runowska, Jacek Wójtowski, Alicja Niewiadomska, Maria Markiewicz-Keszycka

Articles

Mares’ milk is characterised by unique nutritional profile. In this study, the microbiological analysis of mares’ milk was performed. The presence of total bacteria, total lactic bacteria, Lactobacillus spp., Streptococcus lactis, Salmonella spp. and coliforms was investigated. Moreover, the influence of refrigerated and frozen storage on the total bacteria count, vitamin C, acidity and colour of milk was examined. Pathogenic Salmonella spp. and coliforms were not detected in the raw milk. It was revealed that mares’ milk can be stored for 72 hours under refrigeration at a temperature of +4 °C without reducing its microbiological quality. Most of the physicochemical …

Effects Of Nonthermal Plasma Technology On Functional Food Components, Aliyu Idris Muhammad, Xinyu Liao, Patrick J. Cullen, Donghong Liu, Qisen Xiang, Jun Wang, Shiguo Chen, Xingqian Ye, Tian Ding

Articles

Understanding the impact of nonthermal plasma (NTP) technology on key nutritional and functional food components is of paramount importance for the successful adoption of the technology by industry. NTP technology (NTPT) has demonstrated marked antimicrobial efficacies with good retention of important physical, chemical, sensory, and nutritional parameters for an array of food products. This paper presents the influence of NTPT on selected functional food components with a focus on low-molecular-weight bioactive compounds and vitamins. We discuss the mechanisms of bioactive compound alteration by plasma-reactive species and classify their influence on vitamins and their antioxidant capacities. The impact of NTP on …

Lignocellulosic Biorefineries In Europe: Current State And Prospects, Amit Jaiswal, Shady Hassan, Gwilym A. Williams

Articles

In 2012, the European Bioeconomy strategy was launched, defining the bioeconomy as "the 33 production of renewable biological resources and the conversion of these resources and waste 34 streams into value added products". This strategy and its action plans increased the turnover 35 of the total bioeconomy in the EU from 2.09 trillion Euro in 2008 to 2.29 trillion in 2015 .

Lactic Acid Fermentation Of Arthrospira PlatensisIs (Spirulina) Biomass For Probiotic-Based Products, Alberto Niccolai, Emer Shannon, Nissreen Abu-Ghannam, Natascia Biondi, Liliana Rodolfi, Mario R. Tredici

Articles

The first objective of this study was to evaluate the use of lyophilised biomass of the cyanobacterium Arthrospira platensis F&M-C256 as the sole substrate for lactic acid fermentation by the probiotic bacterium Lactobacillus plantarum ATCC 8014. After 48 h of fermentation, the bacterial concentration was 10.6 log CFU mL−1 and lactic acid concentration reached 3.7 g L−1. Lyophilised A. platensis F&M-C256 biomass was shown to be a suitable substrate for L. plantarum ATCC 8014 growth. The second objective of the study was to investigate whether lactic acid fermentation could enhance in vitro digestibility and antioxidant activity of A. platensis biomass. …

Implementation Of A Quit Smoking Programme In Community Adult Mental Health Services–A Qualitative Study, Annette Burns, Margaret Webb, Greg Stynes, Tom O'Brien, Daniela Rohde, Judith Strawbridge, Luke Clancy, Frank Doyle

Articles

Little is known about the experiences of people with severe mental health difficulties in smoking cessation interventions. This study aimed to review the implementation of a smoking cessation programme across 16 community mental health day services. The aim was to establish the experience from both service user and facilitator perspectives and refine implementation for future groups. In-depth interviews were conducted with 20 service users and four focus groups held with 17 facilitators. Thematic analysis was used to analyse the data for emergent themes in relation to key enablers and barriers to implementation. Data from service users and facilitators revealed that …

Understanding The Differences Between Antimicrobial And Cytotoxic Properties Of Plasma Activated Liquids, Eva Tsoukou, Paula Bourke, Daniela Boehm

Articles

The aqueous environment plays an important role in the transmission of cold plasma effects to both prokaryotic and eukaryotic cells. The exposure of liquids to cold atmospheric plasma discharges results in the generation of secondary reactive species; specifically, hydrogen peroxide (H2O2) seems to be one of the most important amongst the reactive species contained in plasma activated liquids (PALs) in causing cytotoxicity. Detailed understanding of the effects of PALs on cells is essential to harness this new technology. Liquids acting as models for non-complex solutions were generated using a dielectric barrier discharge atmospheric cold plasma (DBD-ACP) system. The chemical characterization …

Hydra As A Model For Screening Ecotoxicological Effects Of Plasma-Treated Water, Dana Ziuzina, Chaitanya Sarangapani, Daniela Boehm, Paula Bourke

Articles

Atmospheric cold plasma (ACP) has been widely researched to generate functionalized solutions for decontamination of liquids and wastewater treatment. The present investigation demonstrates that Hydra can be used as an additional in vivo tool to monitor the impact of plasma-processed solutions on the aquatic environment.

The N-Acyltransferase Lnt: Structure-Function Insights From Recent Simultaneous Studies, Wei Chang, Declan A. Doyle, Toufic El Arnaout

Articles

Bacterial lipoproteins have been researched for decades due to their roles in a large number of biological functions. There were no structures of their main three membrane processing enzymes, until 2016 for Lgt and LspA, and then 2017 for Lnt with not one but three simultaneous, independent publications. We have analyzed the recent findings for this apolipoprotein N-acyltransferase Lnt, with comparisons between the novel structures, and with soluble nitrilases, to determine the significance of unique features in terms of substrate's recognition and binding mechanism influenced by exclusive residues, two transmembrane helices, and a flexible loop.

An Investigation Of High Intensity Ultrasonication And Chemical Immersion Treatments On Campylobacter Jejuni And Spoilage Bacteria In Chicken, Ahmed Kassem, Joseph Meade, Kevina Mcgill, Ciara Walsh, James Gibbons, James Lyng, Paul Whyte

Articles

High intensity ultrasonication (US) alone or in combination with chemical immersion treatments of lactic acid (3% LA), sodium decanoate (3% SD) and trisodium phosphate (10% TSP) were investigated to reduce populations of Campylobacter jejuni and spoilage organisms in raw chicken. Different experimental conditions were used including a range of temperatures (4°C, 25°C and 54°C) and exposure times (1, 2 and 3min). All combination treatments significantly reduced C. jejuni compared to their individual treatments while only the combination US+SD significantly reduced Total Viable Count (TVC). Multiple linear regression predicted bacterial reductions resulting from changing treatment, temperature and time or each group …

The Effect Of Non-Thermal Plasma On The Lipid Oxidation And Microbiological Quality Of Sushi, Piotr Kulawik, Carlos Alvarez, Patrick J. Cullen, Ramon Aznar-Roca, Anne Maria Mullen, Brijesh Tiwari

Articles

The study examined the effect of non-thermal plasma (NTP) on the total viable count and lipid oxidation of two common sushi products: nigiri and hosomaki. Sushi samples were treated with NTP using a dielectric barrier discharge system with 70 and 80kV of potential differences for 5min. The samples were stored at 4°C for 11days and analysed for total aerobic count, moisture and protein content, TBA index and fatty acids composition. Although the effect of NTP on the total aerobic counts was not statistically significant, a tendency in log reduction could be observed, with 1–1.5logcfu/g reduction. Moisture and protein content, as …