Digital Commons Network^™

Cold Plasma For Insect Pest Control: Tribolium Castaneum Mortality And Defense Mechanisms In Response To Treatment, Dana Ziuzina, Robin Van Cleynenbreugel, Paula Bourke

Articles

The insecticidal properties and mechanisms of high-voltage air-based atmospheric cold plasma using a contained dielectric barrier discharge reactor were investigated against Tribolium castaneum as an important bio-contaminant in stored grains spoilage. The mortality of 95.0%–100% for preadult stages can be achieved within seconds of treatment, but longer plasma exposure (5 min) is required to kill adult insects. Cold plasma treatment reduces both the respiration rate and the weight of insects and affects the levels of oxidative stress markers in adult populations. Sufficient toxicity is achievable through plasma process control in air to address the range of insect lifecycle stages that …

Mortality Risk Attributable To Wildfire-Related Pm2·5 Pollution: A Global Time Series Study In 749 Locations, Gongbo Chen, Yuming Guo, Xu Yue, Shilu Tong, Antonio Gasparrini Antonio Gasparrini, Michelle L. Bell, Joel Schwartz, Jouni J K Jaakkola, Antonella Zanobetti, Eric Lavigne, Paulo Hilario Nascimento Saldiva, Haidong Kan, Dominic Royé, Ai Milojevic, Ala Overcenco, Aleš Urban, Alexandra Schneider, Alireza Entezari, Ana Maria Vicedo-Cabrera, Ariana Zeka, Aurelio Tobias, Baltazar Nunes, Barrak Alahmad, Bertil Forsberg, Shih-Chun Pan, Carmen Íñiguez, Caroline Ameling, César De La Cruz Valencia, Christofer Åström, Danny Houthuijs, Do Van Dung, Evangelia Samoli, Fatemeh Mayvaneh, Francesco Sera, Gabriel Carrasco-Escobar, Yadong Lei, Hans Orru, Ho Kim, Iulian-Horia Holobaca, Jan Kyselý, João Paulo Teixeira, Joana Madureira, Klea Katsouyanni, Magali Hurtado-Díaz, Marek Maasikmets, Martina S Ragettli, Masahiro Hashizume, Massimo Stafoggia, Mathilde Pascal, Matteo Scortichini, Micheline De Sousa Zanotti Stagliorio Coêlho, Nicolás Valdés Ortega, Niilo R I Ryti, Noah Scovronick, Patricia Matus, Patrick J. Goodman, Rebecca M Garland, Rosana Abrutzky, Samuel Osorio Garcia, Shilpa Rao, Simona Fratianni, Tran Ngoc Dang, Valentina Colistro, Veronika Huber, Whanhee Lee, Xerxes Seposo, Yasushi Honda, Yue Leon Guo, Tingting Ye, Wenhua Yu, Michael J. Abramson, Jonathan M. Samet, Shanshan Li

Articles

Many regions of the world are now facing more frequent and unprecedentedly large wildfires. However, the association between wildfire-related PM2·5 and mortality has not been well characterised. We aimed to comprehensively assess the association between short-term exposure to wildfire-related PM2·5 and mortality across various regions of the world.

Computational Solutions Based On Bayesian Networks To Hierarchize And To Predict Factors Influencing Gender Fairness In The Transport System: Four Use Cases, Gemma Dolores Molero, Sara Poveda-Reyes, Ashwani Kumar Malviya Ashwani Kumar Malviya, Elena García-Jiménez, Maria Chiara Leva, Francisco Enrique Santarremigia

Articles

: Previous studies have highlighted inequalities and gender differences in the transport system. Some factors or fairness characteristics (FCs) strongly influence gender fairness in the transport system. The difference with previous studies, which focus on general concepts, is the incorporation of level 3 FCs, which are more detailed aspects or measures that can be implemented by companies or infrastructure managers and operators in order to increase fairness and inclusion in each use case. The aim of this paper is to find computational solutions, Bayesian networks, and analytic hierarchy processes capable of hierarchizing level 3 FCs and to predict by simulation …

Doctors Can’T Be Doctors All Of The Time: A Qualitative Study Of How General Practitioners And Medical Students Negotiate Public-Professional And Private-Personal Realms Using Social Media, Megan Marshall, Vikram Niranjan, Eimear Spain, Joe Macdonagh, Jane O'Doherty, Raymond O'Connor, Andrew O'Regan

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The objective of this study is to explore the experiences and perspectives of general practitioners’ and medical students’ use of, and behaviour on, social media and to understand how they negotiate threats to professional and personal life on social media.

Plasma-Treated Water Affects Listeria Monocytogenes Vitality And Biofilm Structure, Oliver Handorf

Articles

Plasma-generated compounds (PGCs) such as plasma-processed air (PPA) or plasma-treated water (PTW) offer an increasingly important alternative for the control of microorganisms in hard-to-reach areas found in several industrial applications including the food industry. To this end, we studied the antimicrobial capacity of PTW on the vitality and biofilm formation of Listeria monocytogenes, a common foodborne pathogen.

Food Contact Surfaces: Challenges, Legislation And Solutions, Shubham Sharma, Amit Jaiswal, Brendan Duffy, Swarna Jaiswal

Articles

Food contact surfaces (FCSs) include all surfaces that may come in contact with the food during production, processing, and packaging. Food processing industries encounter several challenges due to its microbial interaction with the FCSs, such as cross-contamination of pathogenic microorganisms or allergens in food, formation of biofilm, biodeterioration of food contact surface leads to food with reduced shelf-life and quality. A legal EU framework provides the fundamental postulates for the safety and inertness of all Food Contact Materials (FCMs). Legislations have an important role in providing regulatory guidance on the quality assurance systems and verifying their implementation as a means …

Blockchain Neutrality, Samuel N. Weinstein

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Blockchain technology is transforming how markets work. Blockchains eliminate the need for trusted gatekeepers like banks to execute, verify, and record transactions. In the financial markets, their disruptive potential threatens both Wall Street banks and Silicon Valley venture capitalists. How blockchain technology is regulated will determine whether it encourages or inhibits competition. Some blockchain applications present serious fraud and systemic risks, complicating regulation. This Article explores the antitrust and competition policy challenges blockchain presents and proposes a regulatory strategy, modeled on Internet regulation and net neutrality principles, to unlock blockchain’s competitive potential. It contends that financial regulators should promote blockchain …

School Performance And Undetected And Untreated Visual Problems In Schoolchildren In Ireland; A Population-Based Cross-Sectional Study, Síofra Harrington, Peter Davison, Veronica O'Dwyer

Articles

This study explored the association between children’s vision and their school academic progress as reported by parents/guardians. Participants were 1,612 schoolchildren (722 6-7-year-olds, 890 12-13-year-olds) in randomly selected schools in Ireland. In advance of data collection, parents/guardians reported school performance as (a) much better than classmates (high-performance) (b) about the same as classmates (average-performance) (c) not as well as classmates (low-performance). Measurements included logMAR monocular visual acuities (with spectacles if worn, and pinhole) in the distance (3 m) and near (40 cm); the amplitude of accommodation; stereoacuity, colour vision assessment, and cyclopleged autorefraction. Controlling for confounders, children presenting with visual …

Prevalence And Associated Risk Factors Of Symptomatic Dry Eye In Ghana: A Cross-Sectional Population-Based Study, Emmnuel Kobia Acquah, Stephen Ankamah-Lomotey, Ebenezer Owusu, Sedinam Forfoe, Joseph Bannor, Joana Abokoma Koomson, Martin Opoku, Daniel Mensah Dzikpo, Derrick Nii Okaikwei Mensah, Jedidiah N. Amonoo, Prince Kwaku Akowuah

Articles

Purpose This study sought to estimate the prevalence and associated risk factors of symptomatic dry eye in the general non-clinical Ghanaian population.

Methods This was a cross-sectional population-based study conducted from November 2019 to February 2020. A stratified, multistage, random sampling technique was used to select participants aged 18 years and above from the capital cities of eight administrative regions in Ghana. Symptomatic dry eye was assessed using the Ocular Surface Disease Index questionnaire (OSDI). A study specific structured questionnaire was administered to collect information on participants’ demographics and self-reported risk factors of dry eye disease such as smoking, diabetes, …

Raman Spectral Cytopathology For Cancer Diagnostic Applications, Damien Traynor, Isha Behl, Declan O'Dea, Franck Bonnier, Siobhan Nicholson, Finbar O'Connell, Aoife Maguire, Stephen Flint, Sheila Galvin, Claire M. Healy, Cara M. Martin, John J. O'Leary, Alison Malkin, Hugh J. Byrne, Fiona M. Lyng

Articles

Raman spectroscopy can provide a rapid, label-free, nondestructive measurement of the chemical fingerprint of a sample and has shown potential for cancer screening and diagnosis. Here we report a protocol for Raman microspectroscopic analysis of different exfoliative cytology samples (cervical, oral and lung), covering sample preparation, spectral acquisition, preprocessing and data analysis. The protocol takes 2 h 20 min for sample preparation, measurement and data preprocessing and up to 8 h for a complete analysis. A key feature of the protocol is that it uses the same sample preparation procedure as commonly used in diagnostic cytology laboratories (i.e., liquid-based cytology …

Incoherent Radar Imaging For Breast Cancer Detection And Experimental Validation Against 3d Multimodal Breast Phantoms, Antonio Cuccaro, Angela Dell'aversano, Giuseppe Ruvio, Jacinta Browne, Raffaele Solimene

Articles

: In this paper we consider radar approaches for breast cancer detection. The aim is to give a brief review of the main features of incoherent methods, based on beam-forming and Multiple SIgnal Classification (MUSIC) algorithms, that we have recently developed, and to compare them with classical coherent beam-forming. Those methods have the remarkable advantage of not requiring antenna characterization/compensation, which can be problematic in view of the close (to the breast) proximity set-up usually employed in breast imaging. Moreover, we proceed to an experimental validation of one of the incoherent methods, i.e., the I-MUSIC, using the multimodal breast phantom …

Acute Growth Inhibition & Toxicity Analysis Of Nano-Polystyrene Spheres On Raphidocelis Subcapitata, Anthony Reynolds, Michelle Giltrap, Gordon Chambers

Articles

Micro/nano-plastics (MNPs) have been found within many environments and organisms including humans, making them a significant and growing concern. Initial research into the potential detrimental effects these MNPs both from acute and chronic exposure has been ongoing but still requires substantially more data to clarify. This research presents the response of nano-polystyrene (NPS) on Raphidocelis subcapitata, a freshwater alga, under an existing acute toxicity test along with additional analytical techniques to try identifying possible sources of toxicity. R. subcapitata cells were exposed for 72 h to a concentration range of 0–100 mg/l NPS. Growth Inhibition (GI) testing showed the …

Discrimination Of Immune Cell Activation Using Ramanmicro-Spectroscopy In Anin-Vitro & Ex-Vivo Model, Neha Chaudhary, Thi Nguyet Que Nguyen, Daniel Cullen, Aidan Meade, Claire Wynne

Articles

Activation and proliferation of immune cells such as lymphocytes and monocytes are appropriate inflammatory responses to invading pathogens and are key to overcoming an infection. In contrast, uncontrolled and prolonged activation of these cellular signalling pathways can be deleterious to the body and result in the development of autoimmune conditions. The understanding of cellular activatory status therefore plays a significant role in disease diagnosis and progression. Conventional automated approaches such as enzyme linked immunosorbent assays (ELISA) and immune-labelling techniques are time-consuming and expensive, relying on a commercially available and specific antibody to identify cell activation. Developing a label-free method for …

Optical Fibre Based Real-Time Measurements During An Ldr Prostate Brachytherapy Implant Simulation: Using A 3d Printed Anthropomorphic Phantom, P. Woulfe, Francis John Sullivan, L. Byrne, Andrea Jane Doyle, W. Kam, M. Martin, S. O'Keeffe

Articles

An optical fbre sensor based on radioluminescence, using the scintillation material terbium doped gadolinium oxysulphide (Gd2O2S:Tb) is evaluated, using a 3D printed anthropomorphic phantom for applications in low dose-rate (LDR) prostate brachytherapy. The scintillation material is embedded in a 700 µm diameter cavity within a 1 mm plastic optical fbre that is fxed within a brachytherapy needle. The high spatial resolution dosimeter is used to measure the dose contribution from Iodine-125 (I-125) seeds. Initially, the efects of sterilisation on the sensors (1) repeatability, (2) response as a function of angle, and (3) response as a function of distance, are evaluated …

Evaluation Of Postoperative Refractive Error Correction After Cataract Surgery, Ellen Konadu Antwi-Adjei, Emmanuel Owusu, Emmanuel Kobia-Acquah, Emmanuella Esi Dadzie, Emmanuel Anarfi, Seth Wanye

Articles

Suboptimal cataract surgery outcomes remain a challenge in most developing countries. In Ghana, about 2 million people have been reported to be blind due to cataract with about 20% new cases being recorded yearly. The aim of this study was to evaluate postoperative correction of refractive errors after cataract surgery in a selected eye hospital in Ashanti Region, Ghana. This was a retrospective study where medical records of patients (aged 40–100) who reported to an eye hospital in Ghana from 2013–2018 were reviewed. Included in the study were patients aged ≥40 years and patients with complete records. Data on patient …

Cantilever-Based Sensor Utilizing A Diffractive Optical Element With High Sensitivity To Relative Humidity, Catherine M. Grogan, Faolan Radford Mcgovern, Rory Staines, George Amarandei, Izabela Naydenova

Articles

High-sensitivity and simple, low-cost readout are desirable features for sensors independent of the application area. Micro-cantilever sensors use the deflection induced by the analyte presence to achieve high-sensitivity but possess complex electronic readouts. Current holographic sensors probe the analyte presence by measuring changes in their optical properties, have a simpler low-cost readout, but their sensitivity can be further improved. Here, the two working principles were combined to obtain a new hybrid sensor with enhanced sensitivity. The diffractive element, a holographically patterned thin photopolymer layer, was placed on a polymer (polydimethylsiloxane) layer forming a bi-layer macro-cantilever. The different responses of the …

Raman Spectroscopy Is Sensitive To Biochemical Changes Related To Various Cartilage Injuries, Rubina Shaikh, Ervin Nippolainen, Vesa Virtanen, Jari Torniainen, Lassi Rieppo, Simo Saarakkala, Isaac O. Afara, Juha Töyräs

Articles

Raman spectroscopy is promising in vivo tool in various biomedical applications; moreover, in recent years, its use for characterizing articular cartilage degeneration has been developing. It has also shown potential for scoring the severity of cartilage lesions, which could be useful in determining the optimal treatment strategy during cartilage repair surgery. However, the effect of different cartilage injury types on Raman spectra is unknown. This study aims to investigate the potential of Raman spectroscopy for detecting changes in cartilage due to different injury types. Artificial injuries were induced in cartilage samples using established mechanical and enzymatic approaches to mimic trauma-induced …

The Role Of Direct Oral Anticoagulants In Advanced Chronic Kidney Disease–Questions And Future Directions, Filip Ionescu, Saima Mansuri

Articles

With the advent of the direct oral anticoagulants (DOACs), patients requiring anticoagulation for common conditions such as atrial fibrillation and venous thromboembolism no longer need to worry about dietary restrictions or regular monitoring of the international normalized ratio which complicated warfarin treatment. Switching from warfarin to apixaban, a DOAC, has been shown to improve patient satisfaction by reducing treatment burden [1]. The clotting factor Xa inhibitors (apixaban, rivaroxaban, and edoxaban) and the direct thrombin inhibitors (argatroban and dabigatran) have shown non-inferiority in preventing thromboembolic events and a superior safety profile in terms of bleeding and several trials when compared to …

Stripped Of Funds, Stripped Of Rights: A Critique Of Guardianship As A Remedy For Elder Financial Harm, Rebekah Diller, Leslie Salzman

Articles

There is a growing consensus in the United States and abroad recognizing the right to “legal capacity”—the right to make legally binding decisions for oneself—as a basic human right. Despite this recognition, adult guardianship—the state court procedure by which a person is declared incapacitated and stripped of decision-making rights—remains a widely used tool, particularly for older adults who have suffered financial exploitation or loss. For this population, guardianship is considered an unpleasant yet necessary remedy to address their financial harms. But what if the cure does not really work as intended, while other, less intrusive means could prevent and redress …

Courts Beyond Judging, Michael C. Pollack

Articles

Across all fifty states, a woefully understudied institution of government is responsible for a broad range of administrative, legislative, law enforcement, and judicial functions. That important institution is the state courts. While the literature has examined the federal courts and federal judges from innumerable angles, study of the state courts as institutions of state government — and not merely as sources of doctrine and resolvers of disputes — has languished. This Article remedies that oversight by drawing attention for the first time to the wide array of roles state courts serve, and by evaluating the suitability of both the allocation …

Towards An Improved Understanding Of Biogeochemical Processes Across Surface-Groundwater Interactions In Intermittent Rivers And Ephemeral Streams, Lluís Gómez-Gener

Articles

Surface-groundwater interactions in intermittent rivers and ephemeral streams (IRES), waterways which do not flow year-round, are spatially and temporally dynamic because of alternations between flowing, non-flowing and dry hydrological states. Interactions between surface and groundwater often create mixing zones with distinct redox gradients, potentially driving high rates of carbon and nutrient cycling. Yet a complete understanding of how underlying biogeochemical processes across surface-groundwater flowpaths in IRES differ among various hydrological states remains elusive. Here, we present a conceptual framework relating spatial and temporal hydrological variability in surface water-groundwater interactions to biogeochemical processing hotspots in IRES. We combine a review of …

Food Industries Wastewater Recycling For Biodiesel Production Through Microalgal Remediation, Divakar Dahiya, Uttam K. Ghosh, Poonam S. Nigam, Amit Jaiswal

Articles

This article is an overview of a biosystem of food-industry wastewater (WW) treatment using microalgae towards circular bioeconomy through biosynthesis of compounds of added-value. Focusing on circular bioeconomy with concern to environmental pollution, the management of water-resource and energy-crisis could be combined; by upgrading conventional WW treatment and simultaneously producing a renewable and sustainable source of energy algal-lipids for biodiesel production. Phyco-remediation of food WW using microalgae has revealed many advantages that can fulfill new demands for the WW treatment. WWs can be valuable resources of micronutrients and organic content (carbon source) for algal cultivation. In this review, prospective routes …

Socio-Economic Factors Associated With The Incidence Of Shiga-Toxin Producing Escherichia Coli (Stec) Enteritis And Cryptosporidiosis In The Republic Of Ireland, 2008–2017, Eiimear Cleary, Martin Boudou, Coilín Oscar Óhaiseadha, Patricia Garvey, Paul Mckeown, Jean O'Dwyer, Paul Hynds

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The Republic of Ireland (ROI) currently reports the highest incidence rates of Shiga-toxin producing Escherichia coli (STEC) enteritis and cryptosporidiosis in Europe, with the spatial distribution of both infections exhibiting a clear urban/rural divide. To date, no investigation of the role of socio-demographic profile on the incidence of either infection in the ROI has been undertaken. The current study employed bivariate analyses and Random Forest classification to identify associations between individual components of a national deprivation index and spatially aggregated cases of STEC enteritis and cryptosporidiosis. Classification accuracies ranged from 78.2% (STEC, urban) to 90.6% (cryptosporidiosis, rural). STEC incidence was …

Spatiotemporal Epidemiology Of Cryptosporidiosis In The Republic Of Ireland, 2008–2017: Development Of A Space–Time “Cluster Recurrence” Index, Martin Boudou

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Approximately 1.5 million individuals in Ontario are supplied by private water wells (private groundwater supplies). Unlike municipal supplies, private well water quality remains unregulated, with owners responsible for testing, treating, and maintaining their own water supplies. The COVID-19 global pandemic and associated non-pharmaceutical interventions (NPIs) have impacted many environmental (e.g., surface water and air quality) and human (e.g., healthcare, transportation) systems over the past 15-months (January 2020 to March 2021). To date, the impact of these interventions on private groundwater systems remains largely unknown. Accordingly, the current study aimed to investigate the impact of a province-wide COVID-19 lockdown (late-March 2020) …

Spatiotemporal Dynamics Of Sporadic Shiga Toxin–Producing Escherichia Coli Enteritis, Ireland, 2013–2017, Eiimear Cleary, Patricia Garvey, Paul Mckeown, Jean O'Dwyer, Coilin Oh Aiseadha, Paul Mckeown, Paul Hynds

Articles

The Republic of Ireland regularly reports the highest annual crude incidence rates of Shiga toxin–producing Escherichia coli (STEC) enteritis in the European Union, ≈10 times the average. We investigated spatiotemporal patterns of STEC enteritis in Ireland using multiple statistical tools. Overall, we georeferenced 2,755 cases of infection during January 2013–December 2017; we found >1 case notified in 2,340 (12.6%) of 18,641 Census Small Areas. We encountered the highest case numbers in children 0–5 years of age (n = 1,101, 39.6%) and associated with serogroups O26 (n = 800, 29%) and O157 (n = 638, 23.2%). Overall, we identified 17 space-time …

Modelling Covid‑19 Severity In The Republic Of Ireland Using Patient Co‑Morbidities, Socioeconomic Profle And Geographic Location, February To November 2020, Martin Boudou, C. Óhaiseadha, P. Garvey, John O'Dwyer, Paul Hynds

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Understanding patient progression from symptomatic COVID-19 infection to a severe outcome represents an important tool for improved diagnoses, surveillance, and triage. A series of models have been developed and validated to elucidate hospitalization, admission to an intensive care unit (ICU) and mortality in patients from the Republic of Ireland. This retrospective cohort study of patients with laboratory-confirmed symptomatic COVID-19 infection included data extracted from national COVID-19 surveillance forms (i.e., age, gender, underlying health conditions, occupation) and geographically-referenced potential predictors (i.e., urban/rural classification, socio-economic profile). Generalised linear models and recursive partitioning and regression trees were used to elucidate COVID-19 progression. The …

Psychological Impairment And Extreme Weather Event (Ewe) Exposure, 1980–2020: A Global Pooled Analysis Integrating Mental Health And Well-Being Metrics, C. Chique, P. Hynds, M.M. Nyhan, S. Lambert, Martin Boudou, J. O'Dwyer

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Extreme Weather Events (EWEs) impose a substantial health and socio-economic burden on exposed populations. Projected impacts on public health, based on increasing EWE frequencies since the 1950s, alongside evidence of human-mediated climatic change represents a growing concern. To date, the impacts of EWEs on mental health remain ambiguous, largely due to the inherent complexities in linking extreme weather phenomena with psychological status. This exploratory investigation provides a new empirical and global perspective on the psychological toll of EWEs by exclusively focusing on psychological morbidity among individuals exposed to such events. Morbidity data collated from a range of existing psychological and …

Genetic Background Of Antimicrobial Resistance In Multiantimicrobial-Resistant Escherichia Coli Isolates From Feces Of Healthy Broiler Chickens In Tunisia, Mohamed Salah Abbassi, Hajer Kilani, Islem Abid, Yolanda Sáenz, Paul Hynds, Sana Lengliz, Noureddine Ben Chehida, Ilhem Boutiba-Ben Boubaker

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Multiantimicrobial-resistant Escherichia coli isolates are a global human health problem causing increasing morbidity and mortality. Genes encoding antimicrobial resistance are mainly harbored on mobile genetic elements (MGEs) such as transposons and plasmids as well as integrons, which enhance their rapid spread. The aim of this study was to characterize 83 multiantimicrobial-resistant E. coli isolates recovered from healthy broiler chickens. Among 78 tetracycline-resistant isolates, the tetA, tetB, and tetC genes were detected in 59 (75.6%), 14 (17.9%), and one (1.2%) isolates, respectively. The sul1, sul2, and sul3 genes were detected 31 (46.2%), 16 (23.8%), and 6 (8.9%) isolates, respectively, among 67 …

Treatment-Resistant Hypercalcemia From Ectopic Pth Hypersecretion Suspected Secondary To Disseminated Ovarian Cancer, Alexander M. Balinski, Neil J. Khatter, Jeffrey M. Gold, Krishna S. Pothugunta, Vamshi K. Garlapaty, Steven M. Rankin, Christopher A. Thornburn, Jamal Abu-Khaled

Articles

Hypercalcemia of malignancy (HCM) can present secondary to hypersecretion of parathyroid hormone (PTH)-related protein (PTHrP) from malignant tumors, but rare cases of HCM have also been documented due to inappropriate PTH secretion from ectopic neoplasms. Here, we report an unusual case of HCM due to hypersecretion of PTH suspected secondary to a disseminated mucinous ovarian adenocarcinoma. A 45-year-old female presented with severe hypercalcemia and significant elevations in both PTH and PTHrP two weeks after total abdominal hysterectomy with bilateral salpingo-oophorectomy and suboptimal debulking of a newly discovered left ovarian mucinous adenocarcinoma with numerous metastases. Ectopic PTH secretion was highly suspected …

New Federalism And Civil Rights Enforcement, Alexander A. Reinert, Joanna C. Schwartz, James E. Pfander

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Calls for change to the infrastructure of civil rights enforcement have grown more insistent in the past several years, attracting support from a wide range of advocates, scholars, and federal, state, and local officials. Much of the attention has focused on federal-level reforms, including proposals to overrule Supreme Court doctrines that stop many civil rights lawsuits in their tracks. But state and local officials share responsibility for the enforcement of civil rights and have underappreciated powers to adopt reforms of their own. This Article evaluates a range of state and local interventions, including the adoption of state law causes of …