Digital Commons Network^™

Antiviral Activity Of Favipiravir (T-705) Against Lethal Rift Valley Fever Virus Infection In Hamsters, Dionna Scharton

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Rift Valley fever (RVF) is a severe disease affecting both humans and a number of agriculturally important livestock species. The causative agent, RVF virus (RVFV), is primarily transmitted through mosquito bites, with transmission also occurring by exposure to infectious aerosols and direct contact with infected body fluids such as blood. Presently, there are no licensed vaccines or medicines to prevent or treat severe RVFV infection in humans. Favipiravir (T-705) is a novel compound licensed for the treatment of influenza in Japan and presently in Phase III clinical trials in the US, which has demonstrated favorable activity against an attenuated strain …

Engaging Alternative High School Students Through The Design, Development, And Crafting Of Computationally Enhanced Pets, Maneksha Katrine Dumont

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

A new kind of technology combines making in the physical world with computing in the virtual world. These technologies are simultaneously physical and virtual, require the design of artifacts like computer programs and the crafting of physical components. Combining approaches encourage youth to participate in computing who might not otherwise be interested by harnessing existing hobbies and interests. Because fluency with computing is important to success in a 21st century society, increasing the ways in which young people can experience and connect to computing is important. Computational thinking, and with it the process of debugging computer code, is an example …

Linking Temporal And Spatial Variability Of Millennial And Decadal-Scale Sediment Yield To Aquatic Habitat In The Columbia River Basin, Elijah Portugal

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Historically the Columbia River was amongst the most productive salmonidbearing watersheds in North America. Currently, salmonid populations have collapsed and are estimated at ten percent of historic levels. Because of this, there are thirteen, Endangered Species Act (ESA) listed distinct population segments within the Columbia River Basin (CRB). The Bonneville Power Administration (BPA) operates a substantial number of hydroelectric dams within the CRB. As the dams effectively block anadromy and are thought to be extremely detrimental to the long-term persistence of salmonid populations within the CRB, the BPA funds a series of programs to mitigate the impacts of dam operation. …

Nonlinear Weir Hydraulics, Mitchell R. Dabling

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

A hydraulically undersized control structure (i.e., an emergency dam spillway) could result in water overtopping a dam or riverbanks. To increase hydraulic capacity and reduce flooding risk, nonlinear weirs are being used to replace undersized linear weirs during control structure rehabilitation. The complex geometry of a nonlinear weir creates an infinite number of designs and three-dimensional flow patterns. This study investigates four subjects to further knowledge on two types of nonlinear weir, the piano key and labyrinth.

Weir submergence is a condition when the downstream water level of a weir exceeds the weir crest elevation, and can influence the head-discharge …

Ambient Temperature, Calf Intakes, And Weight Gains On Preweaned Dairy Calves, Sheldon D. Holt

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

There has been little research conducted on the physiological response of calves to temperatures outside thermal neutrality and its effects on intake and weight gain. The effects of ambient temperature on Holstein dairy calves intakes and weight gain were evaluated over a 12-month period at the Utah State University Caine Dairy.

Ambient temperature was monitored using a weather station located 1.3 kilometers from the dairy. Calf health was monitored daily using the University of Wisconsin-Madison School of Veterinary Medicine scoring criteria. Calves were fed whole milk and free choice calf starter. Weight gain, wither and hip height, starter intake, and …

Ringtail Distribution, Dermatoglyphics, And Diet In Zion National Park, Utah, Adrian Argie Roadman

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Current scientific knowledge of the ringtail (Bassariscus astutus) is limited, thus impeding appropriate management decisions. Ringtails in Zion National Park, Utah, are rarely seen, but are involved in increasing occurrences of negative interactions with park visitors and employees such as food theft and denning in buildings, interactions which are harmful to both parties. To manage this conflict, an update to the general knowledge about the status of the population is required as the only previous study on ringtails in this area was conducted in the 1960s. Using noninvasive techniques provides dependable large-scale population information. I used two noninvasive detection methods …

Biophysically-Based Measurement Of Plant Water Status Using Canopy Temperature, Christopher K. Parry

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Precision irrigation scheduling is one approach that can conserve water by supplying crops with the minimum amount of water needed for sufficient vegetative growth and final crop yield. Improved methods for irrigation scheduling are needed for arid regions that rely mainly on irrigation for crop water needs, and humid regions that supplement water received from precipitation with added irrigation. Methods that directly determine plant physiological responses to water availability have potential to be significantly more sensitive and accurate than indirect approaches like soil moisture measurement. Stomatal conductance is a rapid physiological response to leaf water potential.

Stomatal conductance in single …

Systematics And Behavioral Evolution Of Spider Wasps (Hymenoptera: Pompilidae), Cecilia Waichert Monteiro

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Spider wasps form a diverse and widespread group of stinging wasps. Although all Pompilidae have similar life history characteristics, there is considerable variation in nesting behavior modes and, thus, this family could be useful for learning about the evolution of nesting behavior in insects. The nesting behavior of many species is well known, the family is monophyletic and easily recognized, and certain species have some degree of pre-sociality, i.e., communal nesting. All these factors suggest that the Pompilidae are an important model group for understanding mechanisms and patterns of behavioral evolution.

Pompilidae, however, are rarely studied and their research potential …

Pathway Pioneer: A Web-Based Metabolic Network Layout Extension, Harsh Dosi

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The number and complexity of genome-scale metabolic networks have seen a rapid growth in the past 10 years. Today, more than 450 genome-scale metabolic reconstructions of biological systems are characterized and existing models are extended. With the growing influence of these reconstructions on biomedical and biological research, the field has observed a shift from an inward focus on method development to an outward focus on application development.

Static state analysis of metabolic networks in textual format is too cumbersome and time consuming. In addition, visualization and arrangement of these networks to facilitate their analysis is an open research problem. A …

Ghrelin Concentrations In Milk And Plasma Of Dairy Cows During Early Lactation, Sameer M. Alhojaily

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Ghrelin is a hormone produced mainly by the cells lining the gastric mucosa. Ghrelin was first extracted from human and rat stomachs, and identified as an endogenous stimulator of growth hormone release. Ghrelin is synthesized and produced in several tissues, but the gastric mucosa remains the major source of circulating ghrelin. Besides growth hormone release, ghrelin stimulates appetite and plays some major roles in different organs. In several studies, ghrelin was described as a hormone with multiple functions and diverse biological actions. Ghrelin exists in two major forms, active ghrelin and inactive ghrelin, and only the active from binds to …

Influence Of Stand Composition On Soil Organic Carbon Stabilization And Biochemistry In Aspen And Conifer Forests Of Utah, Mercedes Román Dobarco

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Social concern about climate change and the elevated level of atmospheric CO2 demands understanding carbon (C) storage and dynamics in forest soils, especially since soils are the largest C reservoir in terrestrial ecosystems, storing two thirds of total C. Quacking aspen (Populus tremuloides Michx.) is an iconic species in western United States that offers multiple ecosystem services, such as habitat and forage for wildlife and cattle, biodiversity, water yield, and C storage. A decline in quaking aspen cover has been documented during the last decades, possibly due to fire suppression and ungulate browsing. A shift from aspen- to conifer-dominated …

Stem Development, Seeding Rate, And Establishment Of Birdsfoot Trefoil (Lotus Corniculatus) For Organic, Grazing-Based Dairies, Sara Hunt

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Birdsfoot trefoil (BFT, Lotus corniculatus L.) is a non-bloating, productive forage legume well suited to grazing-based ruminant production. This thesis presents three studies conducted in the Mountain West applicable to organic management and cultivation of BFT. The first is an analysis of lignification in BFT stems that supports recommendations to harvest BFT at approximately 6 weeks of regrowth, or early bloom. Lignification decreases digestibility and is correlated with high shear force required for grazing animals to break BFT stems. The process of stem lignification was observed by harvesting increasingly mature stems; cutting thin sections of the sixth stem internode, which …

Producing An Ovine Model Of Cystic Fibrosis, Kira Perry Morgado

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Cystic Fibrosis (CF) is an autosomal recessive disease that significantly affects quality of life and lifespan. There are currently no effective animal models of CF that mimic the human disease state. This prevents the development of pharmaceutical treatments for patients. Sheep have been considered for a useful animal model because of their size, life expectancy, and similarities in their anatomy and physiology. In order to generate a sheep transgenic model to study CF we have produced two Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene targeting DNA vectors containing large regions of homology to the CFTR gene in sheep. One of …

Constraints On Patterns Of Abundance And Aggregation In Biological Systems, Kenneth J. Locey

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Understanding the mechanisms that structure biological systems is a primary goal of biology. My research shows that the biological structure is constrained in important ways by general variables such as the number of base pairs in a genome and the number of individuals and species in a community. I used a combination of macroecology, bioinformatics, statistics, mathematics, and advanced computing to pursue my research and published several peer-reviewed scientific manuscripts and open-source software as a result.

I was funded through a combination of fellowships and scholarships awarded by the Utah State University School of Graduate Studies, College of Science, and …

An Algorithm To Recognize Multi-Stable Behavior From An Ensemble Of Stochastic Simulation Runs, Eduardo Monzon

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Synthetic biological designers are demanding tools to help with the design and verification process of new biological models. Some of the most common tools available aggregate multiple simulation results into one “clean” trajectory that hopefully is representative of the system’s behavior. However, for systems exhibiting multiple stable states, these techniques fail to show all the possible trajectories of the system. This work introduces a method capable of detecting the presence of more than one “typical” trajectory in a system, which can also be integrated with other available simulation tools.

Winter Waterbird Ecology On The Great Salt Lake, Utah, And Interactions With Commercial Harvest Of Brine Shrimp Cysts, Anthony J. Roberts

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Interactions among commercial fisheries and birds have been studied in open ocean ecosystems and at aquaculture facilities. On the Great Salt Lake (GSL), Utah, USA, a commercial harvest of brine shrimp (Artemia franciscana) eggs (i.e. cysts) occurs annually during fall and winter. Coinciding with commercial harvest is the use of the GSL by millions of waterbirds which has the potential to result in conflict among industry and birds. The objectives of my research were to examine fall and winter ecology of birds using the GSL and interactions with the brine shrimp cyst harvest. I examined the influence of temperature and …

Substrate Binding And Reduction Mechanism Of Molybdenum Nitrogenase, Zhiyong Yang

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

As a key constituent of proteins, nucleic acids, and other biomolecules, nitrogen is essential to all living organisms including human beings. Dinitrogen represents the largest pool of nitrogen, about 79% of the Earth’s atmosphere, yet it is unusable by most living organisms due to its inertness. There are two ways to fix this inert dinitrogen to usable ammonia. One is the industrial Haber-Bosch process, which needs to be conducted at high temperature and pressure. This process uses a lot of the non-renewable fossil fuel as the energy source. The other major pathway is the biological nitrogen fixation carried out by …

Effect Of Predator Removal On Greater Sage-Grouse (Centrocercus Urophasianus) Ecology In The Bighorn Basin Conservation Area Of Wyoming, Elizabeth Kari Orning

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The decline of greater sage-grouse distribution and population densities across western North America has led conservation, research, and management objectives to focus efforts on understanding sage-grouse populations across their range. The purpose of this study was to gain a better understanding of direct and indirect predation effects on hen survival and nest success of sage-grouse. The project was conducted in Hot Springs and Park Counties in the Bighorn Basin of Wyoming. The study had three main objectives: 1) obtain and quantify the types and impacts of predators on sage-grouse hen survival and nest success, 2) compare the effect predator removals …

Evaluating The Smart Steps For Stepfamilies: Embrace The Journey Program, A Hierarchical Examination, Katie L. Reck

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Over the past decade, relationship education has grown as a means of enhancing couple relations. This study examines the experiences of 2,828 ethnically diverse and low-income adults who participated in the Smart Steps for Stepfamilies: Embrace the Journey program, a 12-hour stepfamily education program. Self-report measures of relationship quality, couple commitment, and relationship instability were gathered prior to and immediately after the Smart Steps intervention as well as six weeks, six months, and one year post-program. Results suggest that stepfamily participants experienced increases in relationship quality; however, these increases reduced to near pre-program levels one year after the programs completion. …

Computer Self-Efficacy, Cognitive Actions, And Metacognitive Strategies Of High School Students While Engaged In Interactive Learning Modules, Harry Budi Santoso

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The purpose of this research was to investigate high school students’ computer self-efficacy, cognitive actions, and metacognitive strategies in a self-regulated learning (SRL) framework while utilizing an interactive learning module. The researcher hypothesized that computer self-efficacy is correlated positively with cognitive actions and metacognitive strategies while the students are engaged with interactive learning modules. This research used a mixed-methods approach to answer the research questions. Two research questions guided this research: (1) How is students’ computer self-efficacy related to cognitive actions and metacognitive strategies while using interactive learning modules?; and (2) How do students plan monitor their cognitive actions, and …

Conventional And Catalytic Pyrolysis Of Pinyon Juniper Biomass, Bhuvanesh Kumar Yathavan

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Pinyon and juniper are invasive woody species which has occupied more than 47 million acres of land in Western United States. Pinyon juniper woodlands domination decreases the herbaceous vegetation, increase bare lands which in turn increases soil erosion and nutrition loss. Thus, The US Bureau of Land Management (BLM) has focused on harvesting these woody species to make room for herbaceous vegetation. The major application of harvested pinyon-juniper (PJ) is low value firewood. Thus, there is a need to develop new high value products from this woody biomass to reduce the cost of harvesting. In this study pyrolysis was carried …

Determination Of The Expression Patterns Of Bovine Non-Classical Major Histocompatibility Complex (Mhc) Class I Proteins, Parveen Parasar

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This project was funded by the United States of Department of Agriculture (USDA), which funds research aimed at improving production and animal health. The aim of this study was to advance knowledge of maternal immune tolerance to the fetus and mechanisms bovine non-classical MHC class I proteins employ to interact with immune cells and render them inert towards the fetus.

A fetus is a tissue graft inside the mother’s uterus yet must be accepted by the mother to maintain a successful pregnancy. Reproductive insufficiency and pregnancy failure are major causes of production loss in cattle, especially in cloned animals. Knowledge …

Acceptance And Commitment Therapy For The Treatment Of Posttraumatic Stress Among Adolescents, Michelle R. Woidneck

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The prevalence of exposure to traumatic events among youth in the United States is alarmingly high. Trauma exposure has been linked to numerous negative outcomes, including the development of posttraumatic stress disorder (PTSD) and problematic posttraumatic stress symptomology. Effective trauma-focused treatments for children and adolescents have been identified; however, these treatments also possess various limitations, including a substantial number of individuals who do not respond, show minimal responsiveness, or drop out before completing treatment. Such limitations indicate that investigation into alternative treatment modalities is warranted.

In collaboration with Utah State University (USU), a psychology professor, Dr. Michael Twohig, and a …

Utilizing Municipal And Industrial Wastes For The Production Of Bioproducts: From Metagenomics To Bioproducts, Joshua T. Ellis

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Developing renewable sources of energy is gaining interest due to limited supplies, rising costs, and environmental impacts of exploiting fossil fuels. Biosolvents such as acetone, butanol, and ethanol are attractive sources of fuel which can aid in replacing our dependence on foreign oil. Butanol is of particular interest due to its ability to directly replace gasoline, thus considered a drop-in-fuel. Biological hydrogen and methane gas are also attractive energy sources that can lower dependence on fossil energy.

This research focused on incorporating DNA sequencing technologies in parallel with fermentation methods for understanding and producing energy. The natural environment provides diverse …

Presence And Function Of Tetrodotoxin In Terrestrial Vertebrates And Invertebrates, Amber N. Stokes

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Tetrodotoxin (TTX) is a potent neurotoxin found in a variety of species. This toxin has long been of concern to human health as it is found in puffer fish, which are a delicacy in Japan. Since the distribution of this toxin is so great, there are many questions regarding the evolution and ecology of organisms that have TTX. My research has focused on further investigating three topics with this research: production, predation, and identification of novel TTX bearing taxa. In order to perform this research I first refined a Competitive Inhibition Enzymatic Immunoassay methodology to quantify levels of TTX in …

Longitudinal Analysis Of Resource Competitiveness And Homelessness Among Young Adults, Mathew F. Prante

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Homelessness occurs when individual resources are not enough for the demands of a given environment. It is not an arbitrary state of being, or a class of individual, it is a marker that signals a person has fallen to the extreme low end of a continuum of poverty. Perceiving homelessness as a point on a spectrum versus a discrete state, leads to research and explanations concerning how someone goes from being housed to being homeless, which can lead to more meaningful results than conceptualizing the homeless population as a class of people. It allows for the exploration of identification markers …

Modeling Habitat Use Of A Fringe Greater Sage-Grouse Population At Multiple Spatial Scales, Anya Cheyenne Burnett

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Greater sage-grouse (Centrocercus urophasianus; hereafter sage-grouse) are a prominent bird species of sagebrush-dominated landscapes across the western United States. Over the past 15 years, sage-grouse have gained international attention due to decreasing population trends despite management efforts. In 2010 the U.S. Fish and Wildlife Service designated this species as warranted for listing under the Endangered Species Act, but the listing was precluded by other species at higher conservation risk. Habitat loss, degradation, and fragmentation have been implicated as primary sources of declines in sage-grouse distribution and abundance. The Bald Hills population in southwestern Utah occupies an area with …

Nutrient And Carbon-Dioxide Requirements For Large-Scale Microalgae Biofuel Production, Benjamin K. Shurtz

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Ever-increasing fuel prices and a limited supply of oil worldwide are threatening our economy and way of life in both the near and distant future. In order to reduce oil
dependence, the US Department of Energy (DOE) has established a goal that by the year 2030, 30% of the US transportation fuel will be renewable. The goal equates to
approximately 60 billion gallons per year of renewable fuel.

In an effort to reach the DOE renewable fuel goal, numerous types of plants are being studied, whose oil can be harvested and refined to serve as replacement fuel.
Among the various …

The Ecology And Genetics Of Schoenoplectus Maritimus, An Important Emergent Macrophyte, Across Diverse Hydrologic Conditions—Implications For Restoration, Amanda Clare Sweetman

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Wetlands in the Intermountain West are typically dominated by large monotypic stands of emergent wetland plants, are highly productive, and support millions of migratory birds as important stops along the Pacific Flyway. In systems with low species diversity, such as these, diversity within a species (intraspecific diversity) can play an important role in population fitness and ecosystem functioning and can impact restoration success. Our research was designed to inform future restoration and management activities by studying the pattern of diversity within and among natural plant populations, and by studying how hydrology and plant materials used in restoration (source and diversity …

Preventative Behavioral Parent Training In A Primary Care Context: Initial Evaluation Of A Universal Prevention Program For Disruptive Behavior Disorders, Jessica L. Malmberg

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

One of the biggest challenges parents face is effectively managing their child’s engagement in various disruptive behaviors including noncompliance, tantrums, and aggression. Typically when children begin exhibiting disruptive behaviors, parents will express their concerns to their pediatricians; however, there are significant barriers to parents gaining adequate guidance due to clinic time constraints, insurance reimbursement issues, and the limited training pediatricians receive in addressing these concerns. As such, children are generally referred to outside mental health clinics where additional barriers arise including waitlist delays and mental health stigmatization. The treatment for conduct problems (CP) that has proven most effective is referred …