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Application Of Probabilistic Methods To Turbine Engine Disk Life Prediction And Risk Assessment, Paul Copp, Ashley Whitney-Rawls, Jace Carter, Tarun Goswami Jul 2022

Application Of Probabilistic Methods To Turbine Engine Disk Life Prediction And Risk Assessment, Paul Copp, Ashley Whitney-Rawls, Jace Carter, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Turbine engine disk life prediction and understanding the associated risk remains a significant challenge for today’s designer. Despite advances made in materials testing and characterization, as well as, the application of damage tolerance and linear elastic fracture mechanics modeling, there remains a void in properly assessing loading, geometry, and material design property variability. Add to this the application of advanced hybrid and composite material systems and the need to accurately deal with material variability is even greater. There still remain incidents of failure of critical components which were not properly accounted for by the existing analytical methods, testing, and inspections …

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Effects Of Pulsatile Flow Rate And Shunt Ratio In Bifurcated Distal Arteries On Hemodynamic Characteristics Involved In Two Patient-Specific Internal Carotid Artery Sidewall Aneurysms: A Numerical Study, Hang Yi, Mark Johnson, Luke C. Bramlage, Bryan Ludwig, Zifeng Yang Jul 2022

Effects Of Pulsatile Flow Rate And Shunt Ratio In Bifurcated Distal Arteries On Hemodynamic Characteristics Involved In Two Patient-Specific Internal Carotid Artery Sidewall Aneurysms: A Numerical Study, Hang Yi, Mark Johnson, Luke C. Bramlage, Bryan Ludwig, Zifeng Yang

Mechanical and Materials Engineering Faculty Publications

The pulsatile flow rate (PFR) in the cerebral artery system and shunt ratios in bifurcated arteries are two patient-specific parameters that may affect the hemodynamic characteristics in the pathobiology of cerebral aneurysms, which needs to be identified comprehensively. Accordingly, a systematic study was employed to study the effects of pulsatile flow rate (i.e., PFR−I, PFR−II, and PFR−III) and shunt ratio (i.e., 75:25 and 64:36) in bifurcated distal arteries, and transient cardiac pulsatile waveform on hemodynamic patterns in two internal carotid artery sidewall aneurysm models using computational fluid dynamics (CFD) modeling. Numerical results indicate that larger PFRs can cause higher wall …

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Undergraduate And Graduate Course Descriptions, 2022 Summer, Wright State University Jul 2022

Undergraduate And Graduate Course Descriptions, 2022 Summer, Wright State University

Course Descriptions

Wright State University undergraduate and graduate course descriptions from Summer 2022.

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Reduction In Operating Room Airborne Particle Burden And Time-Dependent Contamination Of Sterile Instrument Trays With The Use Of A Novel Air Filtration System, Fady Y. Hijji, Andrew D. Schneider, Jeffrey T. Reeves, Michael L. Wilson, Logan Nye, Joseph G. Lyons, Michael J. Prayson, Louis J. Rubino Jul 2022

Reduction In Operating Room Airborne Particle Burden And Time-Dependent Contamination Of Sterile Instrument Trays With The Use Of A Novel Air Filtration System, Fady Y. Hijji, Andrew D. Schneider, Jeffrey T. Reeves, Michael L. Wilson, Logan Nye, Joseph G. Lyons, Michael J. Prayson, Louis J. Rubino

Orthopaedic Surgery Faculty Publications

Introduction Postoperative infections represent a substantial burden to patients and healthcare systems. To improve patient care and reduce healthcare expenditures, interventions to reduce surgical infections must be employed. The crystalline C-band ultraviolet (UV-C) air filtration technology (Aerobiotix Inc., Miamisburg, OH, USA) has been designed to reduce airborne bioburden through high-quality filtration and germicidal irradiation. The purpose of this study was to assess the ability of a novel UV-C air filtration device to reduce airborne particle counts and contamination of surgical instrument trays in an operating room (OR) setting. Materials and methods Thirty sterile instrument trays were opened in a positive-air-flow …

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Vital Signs, Summer 2022, Boonshoft School Of Medicine Jul 2022

Vital Signs, Summer 2022, Boonshoft School Of Medicine

Vital Signs

A seventeen page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

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Numerical Solutions To The Robin Inverse Problem With Nonnegativity Constraints, Weifu Fang, Fu-Rong Lin Jun 2022

Numerical Solutions To The Robin Inverse Problem With Nonnegativity Constraints, Weifu Fang, Fu-Rong Lin

Mathematics and Statistics Faculty Publications

We present iterative numerical methods for solving the inverse problem of recovering the nonnegative Robin coefficient from partial boundary measurement of the solution to the Laplace equation. Based on the boundary integral equation formulation of the problem, nonnegativity constraints in the form of a penalty term are incorporated conveniently into least-squares iteration schemes for solving the inverse problem. Numerical implementation and examples are presented to illustrate the effectiveness of this strategy in improving recovery results.

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A Comprehensive Review On Impact Of Microorganisms On Soil And Plant, Tasaddaq Younas, Muhammad Umer, Aqarab Husnain Gondal, Huma Aziz, Muhammad Shehzad Khan, Abdul Jabbar, Haroon Shahzad, Nadia Masaya Panduro-Tenazoa, Muhammad Jamil, Franklin Ore Areche Jun 2022

A Comprehensive Review On Impact Of Microorganisms On Soil And Plant, Tasaddaq Younas, Muhammad Umer, Aqarab Husnain Gondal, Huma Aziz, Muhammad Shehzad Khan, Abdul Jabbar, Haroon Shahzad, Nadia Masaya Panduro-Tenazoa, Muhammad Jamil, Franklin Ore Areche

Journal of Bioresource Management

Soils have the most diversified microbial communities of any environment on the planet. Bacteria, fungi, algae, and protozoa are all found in abundance in soil. Maintaining a healthy environment for crops requires a strong link between plants and soil microorganisms that are essential for good crop development. Soil bacteria are key regulators of the nutrient cycle. Mineralization, legume nitrogen fixation, and ammonia conversion to plant-available nitrate would all be impossible without bacteria. Effective microorganisms have the ability to boost crop growth and yield. When used in conjunction with organic amendments, these bacteria performs better than to the sole application. It …

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Toxicity And Repellency Of Plant Extract And Termiticide Against Fungus Growing Subterranean Termites (Blattodea: Termitidae), Muhammad Shahid Nisar, Talha Nazir, Shah Zaman, Syed Ismat Hussain, Nasir Ahmad Khan, Hafiz Muhammad Usman Aslam, Wajad Nazeer, Muhammad Akhtar Jun 2022

Toxicity And Repellency Of Plant Extract And Termiticide Against Fungus Growing Subterranean Termites (Blattodea: Termitidae), Muhammad Shahid Nisar, Talha Nazir, Shah Zaman, Syed Ismat Hussain, Nasir Ahmad Khan, Hafiz Muhammad Usman Aslam, Wajad Nazeer, Muhammad Akhtar

Journal of Bioresource Management

Different methods such as physical, biological and chemical are used to manage soil fungus increasing termites. Synthetic insecticide plays a vital part in the management of termites. The pesticide used in big quantities causes phytotoxicity, mammalian toxicity and resistance to pesticides in target pests and insect outbreaks. Intensive pesticides exert chronic effects on living organisms with annoyance for beneficial insects. It also accompanied with environmental hazards and developed resistance. Plant leaves extracts provide a distinct variety of biochemical compounds with diverse prospective uses. Resistance development requires the discovery of fresh biological compounds with a wide spectrum of action. Plant leaves …

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Effectiveness Of Mesoporous Bioglass In Drug Delivery, Sheila Galbreath, Bailey Krueger, Taylor Frazier, Tarun Goswami Jun 2022

Effectiveness Of Mesoporous Bioglass In Drug Delivery, Sheila Galbreath, Bailey Krueger, Taylor Frazier, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Since the invention of bioactive glass 50 years ago, it has become a versatile material used in healthcare in a variety of applications and compositions. Bioactive glass has shown superior capabilities of drug delivery compared to traditional carriers. For example, time-released medications are less likely to reach toxic levels, while delivering a specific, therapeutic dose to a localized area. The objective of this paper is to investigate the properties and effectiveness of mesoporous bioglass (MBG) as a drug delivery carrier. A literature review of various polymer coated 45S5 Bioglass® loaded with vancomycin was analyzed to determine their drug release …

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Design And Finite Element Analysis Of Patient-Specific Total Temporomandibular Joint Implants, Shirish M. Ingawale, Tarun Goswami Jun 2022

Design And Finite Element Analysis Of Patient-Specific Total Temporomandibular Joint Implants, Shirish M. Ingawale, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

In this manuscript, we discuss our approach to developing novel patient-specific total TMJ prostheses. Our unique patient-fitted designs based on medical images of the patient’s TMJ offer accurate anatomical fit, and better fixation to host bone. Special features of the prostheses have potential to offer improved osseo-integration and durability of the devices. The design process is based on surgeon’s requirements, feedback, and pre-surgical planning to ensure anatomically accurate and clinically viable device design. We use the validated methodology of FE modeling and analysis to evaluate the device design by investigating stress and strain profiles under functional/normal and para-functional/worst-case TMJ loading …

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Breeding Biology Of The Sardinian Warbler (Sylvia Melanocephala Melanocephala) In The North-East Of Algeria, Kamel Ramdani, Mohamed Mohamed Kouidri, Mohamed Mohamed Laïd Ouakid, Moussa Houhamdi Jun 2022

Breeding Biology Of The Sardinian Warbler (Sylvia Melanocephala Melanocephala) In The North-East Of Algeria, Kamel Ramdani, Mohamed Mohamed Kouidri, Mohamed Mohamed Laïd Ouakid, Moussa Houhamdi

Journal of Bioresource Management

This work examined the reproductive phenology of the Sardinian warbler (Sylvia melanocephala melanocephala) in North-eastern Algeria, which is its main geographical nesting area. Twenty-eight (28) nests were studied during two successive seasons (2016 and 2017). The results obtained in this study confirm that the nests were constructed at an average height of (01.97±01.04 m) from the ground. The laying period lasted eight (08) weeks (mid-March to the beginning of the second week of May), so fifty-four (54) days. The mean clutch size is (4.14±0.97) eggs per brood. The recorder traits were previously observed in European populations. The average …

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A Comprehensive Investigation Of Novel Ber (Ziziphus Mauritiana) Products From South Punjab, Pakistan, Misbah Sharif, Ambreen Naz, Umar Farooq, Kashif Razzaq, Muhammad Ali Sher, Mahmood Alam Khan, Ummara Waheed, Waqas Hayder, Nosheen Naz, Shabbir Ahmad, Nighat Raza Jun 2022

A Comprehensive Investigation Of Novel Ber (Ziziphus Mauritiana) Products From South Punjab, Pakistan, Misbah Sharif, Ambreen Naz, Umar Farooq, Kashif Razzaq, Muhammad Ali Sher, Mahmood Alam Khan, Ummara Waheed, Waqas Hayder, Nosheen Naz, Shabbir Ahmad, Nighat Raza

Journal of Bioresource Management

Ber also known as jujube (Ziziphus mauritiana) is an evergreen shrub and known as poor man’s apple belongs to the Rhamnacae family. It is a minor fruit of Pakistan with short post-harvest shelf life. The present study was planned to develop jujube products such as jam, syrup, jelly, dehydrated jujubes, pickle, and candied jujube from Dil Bahar cultivar followed by a shelf-life study based on TSS, Ascorbic acid, total sugars, moisture and crude fiber content at prescribed intervals. Results showed higher total phenolic content in Dil Bahar (144.38 mgGAE/100g) cultivar as compared to other cultivars. Shelf life study …

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Determination Of Crop Coefficient Of Hybrid Wheat Under Arid Climate: A Pot Study, Saba Wajid, Muhammad Imran, Hafiz Shahzad Ahmad, Muhammad Zeeshan Gulzar, Tanveer Ul Haq, Abdul Ghaffar, Sarmad Frogh Arshad, Zulqurnain Khan, Kashif Bashir, Hasan Riaz Jun 2022

Determination Of Crop Coefficient Of Hybrid Wheat Under Arid Climate: A Pot Study, Saba Wajid, Muhammad Imran, Hafiz Shahzad Ahmad, Muhammad Zeeshan Gulzar, Tanveer Ul Haq, Abdul Ghaffar, Sarmad Frogh Arshad, Zulqurnain Khan, Kashif Bashir, Hasan Riaz

Journal of Bioresource Management

Climate change increases vulnerabilities for crop productivity in Pakistan. Water crises are increasing with an increase in temperature and change in precipitation patterns due to climate change which ultimately imposed a threat to the food security of the country. Water is indispensable for all plants to complete life cycle as the unavailability of water at critical growth stages drastically affects the development of the plant. The present pot study was conducted for the estimation of crop coefficient of hybrid wheat for irrigation scheduling at Muhammad Nawaz Shareef University of Agriculture, Multan during two growing seasons 2018-19 and 2019-20. In this …

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Comparative Efficacy Of Insecticides Against Cabbage Aphid Brevicoryne Brassicae, A Pest Of Oilseed Rape, Brassica Napus (L.) Under Controlled Conditions, Hassoba Hira, Habib Ali, Arbab Ihsan, Zunnu Raen Akhtar, Salma Ameer, Muhammad Yasin, Asim Ali, Shanzay Nawaz Jun 2022

Comparative Efficacy Of Insecticides Against Cabbage Aphid Brevicoryne Brassicae, A Pest Of Oilseed Rape, Brassica Napus (L.) Under Controlled Conditions, Hassoba Hira, Habib Ali, Arbab Ihsan, Zunnu Raen Akhtar, Salma Ameer, Muhammad Yasin, Asim Ali, Shanzay Nawaz

Journal of Bioresource Management

Rapeseed and mustard is the same group of oilseed crops (Brassica sp.) as well as a significant source of edible oil in Pakistan. The cabbage aphid, Brevicoryne brassicae is considered a major insect pest of oilseed rape, Brassica napus L. and causes significant yield loss. An experiment was conducted in a completely randomized design (CRD) consisting of four insecticidal treatments i.e. Confidor 200 SL (imidacloprid), Mospilan 20 SP (acetamiprid), Arrivo (cypermethrin), Triazophos 40 EC (triazophos) at low to high concentrations along with control treatment to estimate the efficacy of canola leaves against aphid population. Among all insecticide applications …

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Efficacy Of Botanical Plant Extracts On The Population Dynamics Of Cotton Aphid, Aphis Gossypii Glover (Hemiptera; Aphididae), Habib Ali, Salma Ameer, Muhammad Qasim, Sajid Fiaz, Shahbaz Ali, Adnan Noor Shah, Saqlain Zaheer, Basharat Ali, Muhaamad Nawaz, Yasir Ali, Nazir Ahmad Jun 2022

Efficacy Of Botanical Plant Extracts On The Population Dynamics Of Cotton Aphid, Aphis Gossypii Glover (Hemiptera; Aphididae), Habib Ali, Salma Ameer, Muhammad Qasim, Sajid Fiaz, Shahbaz Ali, Adnan Noor Shah, Saqlain Zaheer, Basharat Ali, Muhaamad Nawaz, Yasir Ali, Nazir Ahmad

Journal of Bioresource Management

Synthetic pesticides are excessively consumed to control crop pests but abundant use of chemicals may implicate the whole ecosystem badly in the end. Despite the growing concern, few natural products are commercialized for pest control whilst on-farm use of existing botanically-based pesticides remains a small, but growing, component of crop protection practice. The experiment was conducted to assess the potential trade-offs of using botanical extracts (Neem leaf extract, NLE, and Moringa leaf extract, MLE) along with synthetic insecticide, Confidor 200 SL, against Aphis gossypii Glover. Meanwhile, impact of these insecticides on natural enemies were also determined in the field experiment. …

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Wright State University Libraries Annual Report 2021, Wright State University Libraries Jun 2022

Wright State University Libraries Annual Report 2021, Wright State University Libraries

University Libraries' Annual Reports

The 2021 annual report by the Wright State University Libraries highlighting the various happenings at the University Libraries including staff updates, public services highlights, events, and the newly formed Student Advisory Board.

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New Advances In Fluid–Structure Interaction, Wenli Chen, Zifeng Yang, Gang Hu, Haiquan Jing, Junlei Wang Jun 2022

New Advances In Fluid–Structure Interaction, Wenli Chen, Zifeng Yang, Gang Hu, Haiquan Jing, Junlei Wang

Mechanical and Materials Engineering Faculty Publications

Fluid–structure interactions (FSI) play a crucial role in the design, construction, service and maintenance of many engineering applications, e.g., aircraft, towers, pipes, offshore platforms and long-span bridges. The old Tacoma Narrows Bridge (1940) is probably one of the most infamous examples of serious accidents due to the action of FSI. Aircraft wings and wind-turbine blades can break because of FSI-induced oscillations. To alleviate or eliminate these unfavorable effects, FSI must be dealt with in ocean, coastal, offshore and marine engineering to design safe and sustainable engineering structures. In addition, the act of wind on plants and its resultant wind-induced motions …

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Improving Pain Assessment Using Vital Signs And Pain Medication For Patients With Sickle Cell Disease: Retrospective Study, Swati Padhee, Gary K. Nave Jr, Tanvi Banerjee, Daniel M. Abrams, Nirmish Shah Jun 2022

Improving Pain Assessment Using Vital Signs And Pain Medication For Patients With Sickle Cell Disease: Retrospective Study, Swati Padhee, Gary K. Nave Jr, Tanvi Banerjee, Daniel M. Abrams, Nirmish Shah

Computer Science and Engineering Faculty Publications

Background: Sickle cell disease (SCD) is the most common inherited blood disorder affecting millions of people worldwide. Most patients with SCD experience repeated, unpredictable episodes of severe pain. These pain episodes are the leading cause of emergency department visits among patients with SCD and may last for several weeks. Arguably, the most challenging aspect of treating pain episodes in SCD is assessing and interpreting a patient's pain intensity level. Objective: This study aims to learn deep feature representations of subjective pain trajectories using objective physiological signals collected from electronic health records. Methods: This study used electronic health record data collected …

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Degradation Mechanisms Of Zinc-Air Batteries Used In Hearing Aid, Kelly Hunt, Mallorty Bates, Gerard Klint Simon, Tarun Goswami May 2022

Degradation Mechanisms Of Zinc-Air Batteries Used In Hearing Aid, Kelly Hunt, Mallorty Bates, Gerard Klint Simon, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Hearing aid devices are powered by the oxidation of zinc that occurs within zinc-air batteries. Zinc-air batteries have an average discharge time of 7 days. Therefore, hearing-aid devices need frequent battery replacement. In this paper, degradation mechanisms of zinc-air batteries investigated where a competition mechanism between zinc passivation and dendritic formation dictates the battery life. This research included exposure time from none to 9 days and to document dendritic growth with time. Scanning electron microscope images were taken to quantify the damage growth as well energy dispersive X-ray tests were conducted to comment on the composition changes. The results confirmed …

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Comparison Of Aero Engine Component Lifing Methods, Ashley Whitney-Rawls, Paul Copp, Jace Carter, Tarun Goswami May 2022

Comparison Of Aero Engine Component Lifing Methods, Ashley Whitney-Rawls, Paul Copp, Jace Carter, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Failure of critical engine components such as compressor, fan, and turbine disks during flight can cause the loss of the engine, aircraft, or even life. To reduce the risk of this failure during flight, different methodologies and tools have been developed to determine the safe operating life of these critical disk components. The two most widely used lifing methods, safe-life and damage tolerance, are inherently conservative, retiring all components when a predetermined operating limit is reached. Both methods retire components with theoretical useful life remaining. Additional lifing methods can be used to reduce this conservatism and extend the life of …

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Relationship Between Applied Load And Clearance In Suture Knots, Amena S. Shermadou, Steven R. Lindheim, Jerome L. Yaklic, Tarun Goswami May 2022

Relationship Between Applied Load And Clearance In Suture Knots, Amena S. Shermadou, Steven R. Lindheim, Jerome L. Yaklic, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Ethicon Coated Vicryl absorbable sutures of different diameters were studied in order to determine if a relationship exists between the load and measured clearance. A prototype was designed to simulate knot location. Tensile tests were conducted on the suture knots followed by clearance measurements after each load level was applied. From the results it was concluded that the measured clearance was directly proportional to the amount of load applied to the suture knot. Also, based on the diameter of the suture, the smaller the diameter, the lower was the total displacement of the knot or the clearance.

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Gender-Specific Anterior Cruciate Ligament – Gait Forces, Bharadwaj Cheruvu, Amy Neidhard-Doll, Tarun Goswami May 2022

Gender-Specific Anterior Cruciate Ligament – Gait Forces, Bharadwaj Cheruvu, Amy Neidhard-Doll, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

The purpose of this study was to investigate gender-based differences in gait biomechanics and to evaluate those effects on forces generated on the ACL during walking. Estimation of gender-specific ACL forces in the frontal plane can provide a better understanding of the biomechanical patterns underlying higher female injury risk. The present study used a sample from the Fels Longitudinal Study to test the hypothesis that there are significant gender-differences in frontal plane ACL loading during walking. A cross-sectional sample of 178 participants, including 79 males and 99 females was used to evaluate differences in gait kinetics. Females walked at higher …

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Richard Pearl Interview For The Boonshoft School Of Medicine 50th Anniversary Oral History Project, Richard Pearl, Kristen Dilger May 2022

Richard Pearl Interview For The Boonshoft School Of Medicine 50th Anniversary Oral History Project, Richard Pearl, Kristen Dilger

Boonshoft 50th Anniversary Oral History Project

Kristen Dilger interviews Richard Pearl, a graduate of the Boonshoft School of Medicine. He worked as a pediatric surgeon until his retirement. Part of the class of 1980, Pearl discusses his collegiate career, including why he chose Wright State University's new medical college and talks about what it was like attending the college. He talks about the challenges and processes of attending a new medical college, and how attending the Wright State University Boonshoft School of Medicine assisted him in his early career.

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Simulation Of Gene Regulatory Elements For Biosensing, Mallory Bates, Svetlana Harbough, Tarun Goswami May 2022

Simulation Of Gene Regulatory Elements For Biosensing, Mallory Bates, Svetlana Harbough, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Gene regulatory studies are of significant importance in many scenarios such as mental illness. 21% of U.S adults experience mental illnesses including 1 in 4 active-duty military personnel. Mental health can be identified in the body by different biomarkers. These biomarkers potentially controlled by riboswitches, which are located in mRNA and switch “ON” or “OFF” depending on the concentration of a biomarker. In this research, a known riboswitch reengineered and its response in the presence of a biomarker investigated. We changed computationally PreQ1, a known riboswitch that has the smallest aptamer, and then experimentally tested against biomarkers, dehydroepiandrosterone-sulfate …

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In-Vivo Damage Development In Vena Cava Filter: Study Of A Retrieved Device, Anne Marie Lutz, Tarun Goswami May 2022

In-Vivo Damage Development In Vena Cava Filter: Study Of A Retrieved Device, Anne Marie Lutz, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

This article was prepared from a project assigned in a graduate class, BME 7371, Failure Assessment of Medical Devices, taught at Wright State University by the senior author. The device was donated for the study which was successfully retrieved after 93 days in-vivo. Even-though the mechanical integrity of the device held in-tact, the microscopic observations revealed that the damage via corrosion and scratching took place on the surface of the device. The image reconstructed in 3D using image-J software to determine device roughness and depth-of-pits. Results presented in this paper show that damage starts developing in these devices after the …

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Mechanical Properties Of Nanoparticles In The Drug Delivery Kinetics, Kaivon Assani, Amy Neidhard-Doll, Tarun Goswami May 2022

Mechanical Properties Of Nanoparticles In The Drug Delivery Kinetics, Kaivon Assani, Amy Neidhard-Doll, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Nanoparticle formulation is a recently developed drug delivery technology with enhanced targeting potential. Nanoparticles encapsulate the drug of choice and delivers it to the target via a targeting molecules (ex. antigen) located on the nanoparticle surface. Nanoparticles can even be targeted to deeply penetrating tissue and can be modeled to deliver drugs through the blood brain barrier. These advancements are providing better disease targeting such as to cancer and Alzheimer’s. Various polymers can be manufactured into nanoparticles. The polymers examined in this paper are polycaprolactone (PCL), poly(lactic acid) (PLA), poly(lactic-co-glycolic acid) (PLGA), and poly(glycolic acid) (PGA). The purpose of this …

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Unsupervised Anomaly Detection Via Dual Transformation-Aware Embeddings, Zhipeng Wang, Chunping Hou, Bangbang Ge, Yang Liu, Zhicheng Dong, Zhiqiang Wu May 2022

Unsupervised Anomaly Detection Via Dual Transformation-Aware Embeddings, Zhipeng Wang, Chunping Hou, Bangbang Ge, Yang Liu, Zhicheng Dong, Zhiqiang Wu

Electrical Engineering Faculty Publications

Unsupervised anomaly detection refers to the discovery of unconventional images that are globally or locally different from the training set. Recently, reconstruction-based anomaly detection methods have made great progress. However, most of the existing methods take reconstructing the original image as the goal of latent feature learning. Due to lack of effective semantic guidance, latent features have intrinsic characteristics which retain redundant details of spatial structure. Such information is too general and cause over-expression problem. To solve this problem, in this paper, dual transformation-aware embeddings are coined which aims to achieve a stable model to learn high-level latent features in …

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Faculty Senate Agenda And Minutes, April 25, 2022 Apr 2022

Faculty Senate Agenda And Minutes, April 25, 2022

Faculty Senate Minutes and Agendas

Agenda and minutes from the Wright State University Faculty Senate Meeting held on April 25, 2022

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Nanoparticulate Carriers For Drug Delivery, Samantha Lokelani Crossen, Tarun Goswami Apr 2022

Nanoparticulate Carriers For Drug Delivery, Samantha Lokelani Crossen, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Drug delivery with nanoparticulate carriers is a new and upcoming research area that is making major changes within the pharmaceutical industry. Nanoparticulate carriers are discussed, particularly, engineered nanoparticulate carriers used as drug delivery systems for targeted delivery. Nanoparticulate carriers that are used for drug delivery systems include polymers, micelles, dendrimers, liposomes, ceramics, metals, and various forms of biological materials. The properties of these nanoparticulate carriers are very advantageous for targeted drug delivery and result in efficient drug accumulation at the targeted area of interest, reduced drug toxicity, reduced systemic side effects, and more efficient use of the drug overall. Nanoparticlulate …

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The Guardian Week Of April 18, 2022, Wright State University Student Body Apr 2022

The Guardian Week Of April 18, 2022, Wright State University Student Body

The Guardian Student Newspaper

News articles from The Guardian for the week of April 18, 2022. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.

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