Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Wright State University

Discipline
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 31 - 60 of 586

Full-Text Articles in Entire DC Network

Investigating The Effects Of Human Astroviruses On Aquaporins And Tight Junction Proteins In Vitro, Makalia T. Robinson Jan 2024

Investigating The Effects Of Human Astroviruses On Aquaporins And Tight Junction Proteins In Vitro, Makalia T. Robinson

Browse all Theses and Dissertations

Human Astroviruses (HAstV) are positive sense non-enveloped single stranded RNA viruses. HAstV is divided into classical (serotype 1-8) and non-classical (HAstVMLB 1-3 and HAstV-VA1-5) astroviruses. Classical HAstV is known to cause diarrhea in children, elderly, and immunocompromised patients. Additionally, the etiology of nonclassical HAstV remains unknown. However, recent studies have implicated non-classical HAstV closely associated with immunocompromised patients diagnosed neurological diseases like acute encephalitis. The mechanisms by which HAstV cause diarrhea is currently unknown. Aquaporins (AQPs) are integral membrane proteins that regulate the movement of water and small uncharged molecules across the cell membrane in response to osmotic gradients. Tight …

Go to article

Hepatoprotective Effect Of Berberis Lycium In Αlpha-Naphthylisothiocyanate Induced Cholestatic Mouse Models, Shamaila Bashir, Hassan Hameed, Nida Irshad, Aqsa Ashraf, Muhammad Faizan, Saiyada Fatima Maida Halim, Hafiz M. Mazhar Asjad, Andleeb Batool, Imran Sohail Dec 2023

Hepatoprotective Effect Of Berberis Lycium In Αlpha-Naphthylisothiocyanate Induced Cholestatic Mouse Models, Shamaila Bashir, Hassan Hameed, Nida Irshad, Aqsa Ashraf, Muhammad Faizan, Saiyada Fatima Maida Halim, Hafiz M. Mazhar Asjad, Andleeb Batool, Imran Sohail

Journal of Bioresource Management

Cholestasis is characterized by the obstruction of bile flow from hepatocytes to the intestine. It results in accumulation of bile acids in the liver, which cause oxidative stress, inflammation, apoptosis, fibrosis, and cirrhosis. Till now, the treatment options against cholestasis are limited. Therefore, there is an utmost requirement to develop and evaluate the drugs with potential anti-cholestatic effects. In the current study, the drug-induced cholestasis mouse models were generated via oral administration of α-naphthylisothiocyanate (ANIT). The mice were placed into three groups of six animals each. Group I was the control group and was given saline. The cholestasis model Group …

Go to article

Wright State University's Celebration Of Student Research, Scholarship & Creative Activities From Thursday, October 26, 2023, Wright State University Oct 2023

Wright State University's Celebration Of Student Research, Scholarship & Creative Activities From Thursday, October 26, 2023, Wright State University

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Abstract Books

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Celebration of Student Research, Scholarship & Creative Activities on October 26, 2023.

Go to article

Undergraduate And Graduate Course Descriptions, Fall 2023, Wright State University Oct 2023

Undergraduate And Graduate Course Descriptions, Fall 2023, Wright State University

Course Descriptions

Wright State University undergraduate and graduate course descriptions from Fall 2023

Go to article

Sero-Epidemiology Of Rotavirus Gastroenteritis In Children In Ilorin, Kwara State, Omosigho Omoruyi Pius, Izevbuwa Osazee Ekundayo, Saheed Ibrahim Damilare Aug 2023

Sero-Epidemiology Of Rotavirus Gastroenteritis In Children In Ilorin, Kwara State, Omosigho Omoruyi Pius, Izevbuwa Osazee Ekundayo, Saheed Ibrahim Damilare

Journal of Bioresource Management

Rotavirus is responsible for the most severe dehydrating diarrhea among young children due to gastroenteritis. In this study, we aimed to ascertain the occurrence of childhood gastroenteritis caused by Rotavirus among infants and young children who are younger than 5 years of age in Ilorin, Kwara State and determined the risk factors posing the challenges to be susceptible to diarrhea associated with rotavirus in Ilorin, Kwara State. Diarrhea stool samples were collected from children who passed watery stools, who met predetermined inclusion criteria and who presented at the study hospitals Viz: General Hospital and Specialist Hospital Alagbado and Children Specialist …

Go to article

Long-Term Spring Through Fall Capture Data Of Eptesicus Fuscus In The Eastern Usa Before And After White-Nose Syndrome, Molly Simonis, Lynn K. Hartzler, Joshua Campbell, Timothy C. Carter, Lisa Noelle Cooper, Katelin Cross, Katherine Etchison, Traci, R. Andrew King, Richard J. Reynolds, Yasmeen Samar, Michael Yasmeen, Sarah Stankavich, Gregory G. Turner, Megan A. Rúa Aug 2023

Long-Term Spring Through Fall Capture Data Of Eptesicus Fuscus In The Eastern Usa Before And After White-Nose Syndrome, Molly Simonis, Lynn K. Hartzler, Joshua Campbell, Timothy C. Carter, Lisa Noelle Cooper, Katelin Cross, Katherine Etchison, Traci, R. Andrew King, Richard J. Reynolds, Yasmeen Samar, Michael Yasmeen, Sarah Stankavich, Gregory G. Turner, Megan A. Rúa

Biological Sciences Faculty Publications

Emerging infectious diseases threaten wildlife populations. Without well monitored wildlife systems, it is challenging to determine accurate population and ecosystem losses following disease emergence. North American temperate bats present a unique opportunity for studying the broad impacts of wildlife disease emergence, as their federal monitoring programs were prioritized in the USA throughout the 20 th century and they are currently threatened by the invasive fungal pathogen, Pseudogymnoascus destructans ( Pd ), which causes white-nose syndrome. Here we provide a long-term dataset for capture records of Eptesicus fuscus (big brown bat) across the eastern USA, spanning 16 years before and 14 …

Go to article

Undergraduate And Graduate Course Descriptions, 2023 Summer, Wright State University Jul 2023

Undergraduate And Graduate Course Descriptions, 2023 Summer, Wright State University

Course Descriptions

Wright State University undergraduate and graduate course descriptions from Summer 2023.

Go to article

Assessment Of Antimicrobial Competence Of Epiphytes And Endophytes From Osmium Basilicum And Trigonella Foenum Graecum, Iram Asim, Atia Iqbal, Muhammad Ikrama Tanveer Jun 2023

Assessment Of Antimicrobial Competence Of Epiphytes And Endophytes From Osmium Basilicum And Trigonella Foenum Graecum, Iram Asim, Atia Iqbal, Muhammad Ikrama Tanveer

Journal of Bioresource Management

Plant-associated bacteria are an unexplored group of microorganisms that has enormous potential. These bacteria are the source of finding new antimicrobial substances. The present study aimed to isolate and characterize the epiphytes and endophytes from Osmium basilicum and Trigonella foenum graecum plants and to determine their antimicrobial potential against pathogenic bacteria from Nishtar Hospital Multan, Pakistan. The sum of 18 stems and roots along leaf specimens were assembled as of the plant's Osmium basilicum plus Trigonella foenum graecum as of the distinct locales of the Multan city. Overall 73 bacterial strains were isolated and their colony morphology, gram staining, spore …

Go to article

A Review On Antibiotic Resistance And The Use Of Medicinal Plants In The Management Of Uropathogenic Bacteria, Hubza Ruatt Khan, Mehvish Javeed, Iqra Batool, Rabeea Anwar, Asma Ashraf, Sara Janiad Jun 2023

A Review On Antibiotic Resistance And The Use Of Medicinal Plants In The Management Of Uropathogenic Bacteria, Hubza Ruatt Khan, Mehvish Javeed, Iqra Batool, Rabeea Anwar, Asma Ashraf, Sara Janiad

Journal of Bioresource Management

UTIs are the most prevalent infections and are caused by uropathogenic microbes such as Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus spp. Antibiotic resistance has hampered the management of UTIs over the years, with direct repercussions on the treatment cost, the infection severity, and the duration of hospitalization. This review discussed the route of infections, risk factors connected to UTIs, antibiotic resistance issues as well as an alternative therapy to overcome the problem of antibiotic resistance. The medicinal plants, which have been utilized for thousands of years to cure a variety of ailments, represent a …

Go to article

Biochemical Markers Of Liver Toxicity Among Coal Mine Workers Of Punjab, Pakistan Suffering From Hcv, Aima Iram Batool, Asma Noreen, Naima Huma Naveed, Iram Inayat, Muhammad Fayyaz Ur Rehman, Fariha Idrees, Muhammad Ali Kanwal, Syeda Humaira Jabeen, Hakim Bibi Jun 2023

Biochemical Markers Of Liver Toxicity Among Coal Mine Workers Of Punjab, Pakistan Suffering From Hcv, Aima Iram Batool, Asma Noreen, Naima Huma Naveed, Iram Inayat, Muhammad Fayyaz Ur Rehman, Fariha Idrees, Muhammad Ali Kanwal, Syeda Humaira Jabeen, Hakim Bibi

Journal of Bioresource Management

Hepatitis C is among the leading hepatic disorders in current period through which about 3 % world population has been anguish among them 170 million were diagnosed as persistent carriers. A great range of alteration in liver biochemical parameters were found to be allied with HCV infestation. Current study was designed to evaluate the extent of HCV mediated abnormalities in liver biochemical markers which includes ALT (alanine aminotransferase), AST (Aspartate transaminase), ALP (Alkaline Phosphatase) and serum bilirubin. The study was conducted on coal miners of Punjab province, Pakistan. HCV was primarily diagnosed through one step rapid test device after which …

Go to article

Second Annual Research Symposium Program With Abstracts, Office Of Research Affairs, Boonshoft School Of Medicine Apr 2023

Second Annual Research Symposium Program With Abstracts, Office Of Research Affairs, Boonshoft School Of Medicine

Boonshoft School of Medicine Research Symposium

The program booklet is a compilation of abstracts from oral and poster presentations at Wright State University's First Annual Boonshoft School of Medicine Medical Research Symposium held on April 13, 2023.

Go to article

Evaluation Of Free Radical Scavenging  Activity Of Sauce And Formulation Of Tamarindus Indica (L.) And Prunus Domestica (L.) Fruits, Zulnoreen Sarfaraz, Mehmooda Munazir, Mubashrah Munir, Asma Ahmed, Rehana Badar, Ayesha Tahir Mar 2023

Evaluation Of Free Radical Scavenging  Activity Of Sauce And Formulation Of Tamarindus Indica (L.) And Prunus Domestica (L.) Fruits, Zulnoreen Sarfaraz, Mehmooda Munazir, Mubashrah Munir, Asma Ahmed, Rehana Badar, Ayesha Tahir

Journal of Bioresource Management

The formulation and sauce of Tamarindus indica  (L.) and Prusnus  dometica (L.) are very popular recipes across globe. But, not even a single study existed on free-radical scavenging activity (FRSA) of afore-mentioned recipes. So, the present study was designed to bridge this gap of information. The FRSA of individual samples were also determined and compared with that of combinations of both. The highest value for FRSA among all samples was that of T. indica (158.9732 ± 12.658 % at 100 μg ml-1). It was followed by that of individual extract of P. domestica fruit (96.647 ± 0.554 %). …

Go to article

Phenotypic Diversity Among Fennel (Foeniculum Vulgare) Germplasm Of Pakistan, Shumaila Khalil, Shazia Erum, Mahrine Rashid, Arifa Khan, Asif Javaid, Areej Abbasi, Irum Raza Mar 2023

Phenotypic Diversity Among Fennel (Foeniculum Vulgare) Germplasm Of Pakistan, Shumaila Khalil, Shazia Erum, Mahrine Rashid, Arifa Khan, Asif Javaid, Areej Abbasi, Irum Raza

Journal of Bioresource Management

Fennel is facing continuous challenge with reference to biotic and abiotic stresses that can be solved with the knowledge of available germplasm of fennel in the country or worldwide. Selection of fennel genotype on the basis of research interest can never been accomplished without gene pool. The aim of the present study was to explore the phenotypic diversity among selective fennel accession and identify lines having high yielding potential. In the present study thirty fennel accessions were sown in PGRI, NARC. Irrigation practice was carried out during the growing period. Data was recorded during different growth stages and after harvesting. …

Go to article

Epidemiological Survey Of Bovine Babesia And Theileria Parasites In Buffaloes In District Dera Ismail, Khyber Pakhtunkhwa, Waseem Ullah, Arsalan Khan, Akhtar Ali, Imtiaz Ali Shah, Umm E. Aimen, Imtiaz Khan, Abdul Wadood Jan, Saqib Ali Rustam Mar 2023

Epidemiological Survey Of Bovine Babesia And Theileria Parasites In Buffaloes In District Dera Ismail, Khyber Pakhtunkhwa, Waseem Ullah, Arsalan Khan, Akhtar Ali, Imtiaz Ali Shah, Umm E. Aimen, Imtiaz Khan, Abdul Wadood Jan, Saqib Ali Rustam

Journal of Bioresource Management

Piroplasmosis (babesiosis and theileriosis) are the leading blood parasites responsible for significant economic losses to the dairy enterprises. These parasites are transmitted by Ixodid ticks from a diseased animal to a healthy animal. This study was executed to determine the prevalence of Theileria and Babesia in water buffaloes in District Dera Ismail Khan for their risk assessment. During this trial, 350 random blood samples were obtained from buffalos within the region of District Dera Ismail Khan and examined for Babesia and Theileria parasites using Giemsa staining technique under an oil immersion lens. Forty-eight blood samples were found positive and the …

Go to article

Long-Term Exposure To An Invasive Fungal Pathogen Decreases Eptesicus Fuscus Body Mass With Increasing Latitude, Molly C. Simonis, Lynn K. Hartzler, Gregory G. Turner, Michael R. Scafini, Joseph S. Johnson, Megan A. Rúa Feb 2023

Long-Term Exposure To An Invasive Fungal Pathogen Decreases Eptesicus Fuscus Body Mass With Increasing Latitude, Molly C. Simonis, Lynn K. Hartzler, Gregory G. Turner, Michael R. Scafini, Joseph S. Johnson, Megan A. Rúa

Biological Sciences Faculty Publications

Abstract Invasive pathogens threaten wildlife health and biodiversity. Physiological responses of species highly susceptible to pathogen infections following invasion are well described. However, the responses of less susceptible species (relative to highly susceptible species) are not well known. Latitudinal gradients, which can influence body condition via Bergmann's rule and/or reflect the time it takes for an introduced pathogen to spread geographically, add an additional layer for how mammalian species respond to pathogen exposure. Our goal was to understand how hosts less susceptible to pathogen infections respond to long‐term pathogen exposure across a broad latitudinal gradient. We examined changes in body …

Go to article

A Novel Therapeutic Approach To Regulate Carex8 Protein Expression Through E6-Conjugated Cell Penetrating Peptides, Jared D. Compaleo Jan 2023

A Novel Therapeutic Approach To Regulate Carex8 Protein Expression Through E6-Conjugated Cell Penetrating Peptides, Jared D. Compaleo

Browse all Theses and Dissertations

Adenovirus is a human pathogen that causes cold like symptoms in healthy individuals, which could be lethal in pediatrics and the immunocompromised. In polarized epithelia, adenovirus uses the eight-exon isoform of the Coxsackievirus and Adenovirus Receptor (CAREx8) on the apical surface, to facilitate infection. CAREx8 protein expression level is regulated by the scaffolding protein MAGI-1, using two of its PSD95/Dlg-1/ZO-1 (PDZ) domains: PDZ2 and PDZ4. We previously showed that CAREx8 is degraded after interaction with PDZ4 and rescued following interaction with PDZ2. We then developed a PDZ2 binding decoy molecule (E6) that blocks the interaction between CAREx8 and PDZ2, which …

Go to article

Comparing The Performance Of A Targeted Pull-Down Assay To Shotgun Sequencing For Improving Respiratory Infectious Disease Surveillance, Monica R. Christian Jan 2023

Comparing The Performance Of A Targeted Pull-Down Assay To Shotgun Sequencing For Improving Respiratory Infectious Disease Surveillance, Monica R. Christian

Browse all Theses and Dissertations

Current surveillance focuses on well characterized pathogens such as influenza. Since 2000, there have been multiple outbreaks of respiratory disease. These outbreaks have demonstrated the need for robust and collaborative global efforts to identify, monitor, and contain novel respiratory viruses. This study aims to improve the ability of public health agencies to monitor and respond to respiratory disease outbreaks. Using five respiratory pathogens, this study compares a molecular capture technology from Twist Biosciences to the shotgun sequencing approach of whole transcriptome amplification (WTA, Qiagen) with the goal of determining which method is most effective using cost, usability, and sequencing quality …

Go to article

Besoins Ontologiques Pour La Transformation Des Aliments, D. Dooley, M. Weber, L. Ibanescu, M. Lange, L. Chan, L. Soldatova, C. Yang, R. Warren, Cogan Shimizu, H. Mcginty, W. Hsiao Jan 2023

Besoins Ontologiques Pour La Transformation Des Aliments, D. Dooley, M. Weber, L. Ibanescu, M. Lange, L. Chan, L. Soldatova, C. Yang, R. Warren, Cogan Shimizu, H. Mcginty, W. Hsiao

Computer Science and Engineering Faculty Publications

People often value the sensual, celebratory, and health aspects of food, but behind this experience exists many other value-laden agricultural production, distribution, manufacturing, and physiological processes that support or undermine a healthy population. The complexity of such processes is evident in both every-day food preparation of recipes and in industrial food manufacturing, packaging and storage. An integrated ontology landscape does not yet exist to cover all the entities at work in this farm to fork journey. It seems necessary to construct such a vision by reusing expert-curated fit-to-purpose ontology subdomains. The challenge is to make this merger be, by analogy, …

Go to article

Environmental Toxicants And Human B Cells: Insights From Crispr Editing And Genomic Sequencing, Clayton Allex-Buckner Jan 2023

Environmental Toxicants And Human B Cells: Insights From Crispr Editing And Genomic Sequencing, Clayton Allex-Buckner

Browse all Theses and Dissertations

The human immunoglobulin heavy chain gene locus (IGH) has two 3 prime regulatory regions (3’IGHRR), each containing three enhancers (hs3, hs1.2, hs4). In animal models, the 3’IghRR regulates IgH expression and class switch recombination (CSR) to different Ig isotypes. The 3’IGHRR hs1.2 enhancer in humans is polymorphic in that an invariant sequence (IS) can be repeated one to four times in tandem. The hs1.2 polymorphism is of interest due to its association with several human autoimmune disorders and its potential sensitivity to exogenous substances such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD or dioxin). In mouse models, TCDD inhibits the hs1.2 enhancer and 3’IghRR …

Go to article

Regulation Of Cathepsin L Expression And Activity By Cell Confluence And The Circadian Clock, Prashant Gaikwad Jan 2023

Regulation Of Cathepsin L Expression And Activity By Cell Confluence And The Circadian Clock, Prashant Gaikwad

Browse all Theses and Dissertations

Cathepsin L is a lysosomal cysteine protease that is encoded by the CTSL gene in humans. Previous results have shown that CTSL expression and activity towards the DNA repair protein XPA are elevated in lysates of confluent/quiescent HaCaT keratinocytes. Because other nuclear proteins, including 53BP1 and histone H3, have also been reported to be CTSL substrates under conditions of cell differentiation, senescence, or quiescence, CTSL expression and activity (cleavage) of multiple nuclear proteins was examined in lysates from HaCaT cells and other cell lines at various days after plating and cell confluency. Our study found that adding CTSL inhibitors to …

Go to article

A Fecal Survey To Evaluate The Prevalence Of Enteric Viruses In Laboratory Mice, Amina Khatun Jan 2023

A Fecal Survey To Evaluate The Prevalence Of Enteric Viruses In Laboratory Mice, Amina Khatun

Browse all Theses and Dissertations

The study was conducted to investigate the prevalence of four enteric viruses in mouse research facilities that may not be captured by routine pathogen screening. Fecal samples were collected from contact-sentinel mouse cages between April 2022 and January 2023, and screened for the presence of viral genome by RT-qPCR. Out of a total of 50 samples, murine norovirus and murine astrovirus were detected in two (4%) and one (2%) sample, respectively, while murine adenovirus and murine rotavirus were not detected. Furthermore, all samples were screened for the presence of infectious murine noroviruses and astroviruses using the RAW264.7 and Vero cells …

Go to article

Livestock In Pakistan: An Insight Into Climate Changes And Impacts, Muhammad Jamil, Iram Shakeel, Habib Ullah, Mukhtar Ahmad, Saeed Ullah, Iffat Rasool, Muhammad Tahir, Jaweria Gull, Norina Jabeen, Mubarik Ali Dec 2022

Livestock In Pakistan: An Insight Into Climate Changes And Impacts, Muhammad Jamil, Iram Shakeel, Habib Ullah, Mukhtar Ahmad, Saeed Ullah, Iffat Rasool, Muhammad Tahir, Jaweria Gull, Norina Jabeen, Mubarik Ali

Journal of Bioresource Management

The global livestock sector is expanding at a faster rate than any other agricultural sub-sector. It employs approximately 1.3 billion people and accounts for approximately 40 % of global agricultural output. This industry is one of the most damaging sectors to the world's increasingly scarce water resources, contributing to water pollution from animal wastes, hormones, antibiotics, chemicals from tanneries, pesticides, and fertilizers used to spray feed crop. Climate change harms livestock productivity by changing ecosystem services i.e. water availability, forage quality and quantity, diseases outbreak, and animals stress due to heat shock and reduction of livestock diversity and breeds. Ecosystem …

Go to article

Does The Impact Of Arthritis On Participation In Social Activity Vary By Depression?, Mehnaaz Ali Dec 2022

Does The Impact Of Arthritis On Participation In Social Activity Vary By Depression?, Mehnaaz Ali

Master of Public Health Program Student Publications

Objective As the population’s longevity is increasing over time, the number of comorbidities that individuals are suffering with are also becoming evident. The objective is to determine whether individuals living with arthritis have difficulty in social activity participation while suffering with depression. Using the 2019 National Health Interview Survey, this analysis included males and females between 18 to 85 years of age. The dependent variable was social activity participation, where it was identifying participants whether they are or are not having difficulty taking part in social activities. The primary independent variables were depression and arthritis. Other covariates included the demographics …

Go to article

Bamlanivimab Use In A Military Treatment Facility, Eric Karr, Theodore Chung, Kathryn Burtson, Ronald J. Markert, Devin Kelly Nov 2022

Bamlanivimab Use In A Military Treatment Facility, Eric Karr, Theodore Chung, Kathryn Burtson, Ronald J. Markert, Devin Kelly

Internal Medicine Faculty Publications

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), was first identified in 2019 in Wuhan, China, and has rapidly spread across the world. As of April 2021, SARS-CoV-2 has infected more than 140,000,000 and caused more than 3,000,000 deaths globally. In November 2020, the monoclonal antibody bamlanivimab was approved by the FDA for non-hospitalized patients with SARS-CoV-2 (COVID-19) who possessed risk factors for progression to severe COVID-19. This provided a treatment option that may help prevent hospitalization. Methods Patients who regularly received ambulatory care at a military treatment facility and who were …

Go to article

Impact Of An Education Intervention On Covid-19 Vaccine Hesitancy In A Military Base Population, Peter C. Li, Samuel R. Theis, Devin Kelly, Col Thad Ocampo, Andrew Berglund, Damien Morgan, Ronald J. Markert, Evan Fisher, Kathryn Burtson Nov 2022

Impact Of An Education Intervention On Covid-19 Vaccine Hesitancy In A Military Base Population, Peter C. Li, Samuel R. Theis, Devin Kelly, Col Thad Ocampo, Andrew Berglund, Damien Morgan, Ronald J. Markert, Evan Fisher, Kathryn Burtson

Internal Medicine Faculty Publications

Background: Coronavirus disease 2019 (COVID-19) vaccine hesitancy is a major impediment to achieving herd immunity and overcoming the current pandemic. Our aim was to decrease the prevalence of vaccine hesitancy through an education intervention. Method: An education intervention, consisting of a PowerPoint presentation addressing the two mRNA COVID-19 vaccine concerns/myths and a question and answer panel comprising health care providers from various specialties, was implemented to address vaccine hesitancy among personnel associated with Wright-Patterson Air Force Base through a series of virtual and in-person seminars. Participants completed a post-seminar survey as a retrospective self-assessment to identify attitudes and views surrounding …

Go to article

Therapeutic Efficacies Of Nano Carriers In Delivering Drugs, Bailey Krueger, Taylor Frazier, Sheila Galbreath, Tarun Goswami Oct 2022

Therapeutic Efficacies Of Nano Carriers In Delivering Drugs, Bailey Krueger, Taylor Frazier, Sheila Galbreath, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

The drug release rates of poorly soluble medications such as doxorubicin has been investigated in this paper. Since the drug was fixed, different carriers used to deliver it and their release rates compiled from literature were evaluated in this paper. Even though targeting of drugs is very important in drug delivery, it is not within the scope of this paper. However, functionalization of the carrier may provide this benefit, those constructs are included for comparison in terms of hybrid constructs. Dendrimer, micelles and hybrid constructs used in the delivery of doxorubicin compared in this paper with respect to carrier size …

Go to article

Therapeutic Efficacies Of Nano Carriers In Delivering Drugs, Bailey Krueger, Taylor Frazier, Sheila Galbreath, Tarun Goswami Oct 2022

Therapeutic Efficacies Of Nano Carriers In Delivering Drugs, Bailey Krueger, Taylor Frazier, Sheila Galbreath, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

The drug release rates of poorly soluble medications such as doxorubicin has been investigated in this paper. Since the drug was fixed, different carriers used to deliver it and their release rates compiled from literature were evaluated in this paper. Even though targeting of drugs is very important in drug delivery, it is not within the scope of this paper. However, functionalization of the carrier may provide this benefit, those constructs are included for comparison in terms of hybrid constructs. Dendrimer, micelles and hybrid constructs used in the delivery of doxorubicin compared in this paper with respect to carrier size …

Go to article

Biodiversity Of Culicidae (Insecta: Diptera) In The Region Of Khenchela (Northeast Algeria), Imane Halimi, Fatima Zohra Zohra Kara-Toumi, Salim Lebbal, Ruben Bueno Mari, Asma Ghorab, Fairouz Saidi Sep 2022

Biodiversity Of Culicidae (Insecta: Diptera) In The Region Of Khenchela (Northeast Algeria), Imane Halimi, Fatima Zohra Zohra Kara-Toumi, Salim Lebbal, Ruben Bueno Mari, Asma Ghorab, Fairouz Saidi

Journal of Bioresource Management

Mosquitoes are considered as vectors of serious human diseases. The prevention of parasitic and arboviral vector-borne diseases is based mostly on vector control strategies. This control cannot be effective unless a strong knowledge of mosquito biology and distribution in the working area. In this context, and in order to improve the knowledge on the specific diversity of the culicids fauna in the region of Khenchela (northeast of Algeria), an inventory of mosquitoes was carried out for the first time in this region. Larval collection was conducted in various types of habitats through continuous monitoring of seven sites from May 2020 …

Go to article

Suppression Of Store-Operated Calcium Entry Channels And Cytokine Release By Cannabinoids, J. Ashot Kozak Sep 2022

Suppression Of Store-Operated Calcium Entry Channels And Cytokine Release By Cannabinoids, J. Ashot Kozak

Neuroscience, Cell Biology & Physiology Faculty Publications

No abstract provided.

Go to article

Presence Of Blaper-1 And Blaveb-1 Beta-Lactamase Genes Among Isolates Of Pseudomonas Aeruginosa From Burn And Trauma Hospital Peshawar, Pakistan, Suleman Khan, Samiyah Tasleem, Alfarah Rehmat Ullah,, Sarwat Moon, Saad Alghamdi, Raina Saad Suliman, Muhammad Ateeq, Muhmmad Salman, Anas S. Dablool,, Banan Atwah, Farkad Bantun Jun 2022

Presence Of Blaper-1 And Blaveb-1 Beta-Lactamase Genes Among Isolates Of Pseudomonas Aeruginosa From Burn And Trauma Hospital Peshawar, Pakistan, Suleman Khan, Samiyah Tasleem, Alfarah Rehmat Ullah,, Sarwat Moon, Saad Alghamdi, Raina Saad Suliman, Muhammad Ateeq, Muhmmad Salman, Anas S. Dablool,, Banan Atwah, Farkad Bantun

Journal of Bioresource Management

Pseudomonas aeruginosa spp are the most prevalent bacteria that cause nosocomial infections in hospitals. Most antibiotics, including novel new β-lactams, are already resistant to them, and they can become resistant during treatment, which can make the treatment fail. P. aeruginosa isolates from ICU patients who had Per-1 and VEB-1 were the main focus of this study. These two ESBLs are the two most common in ICU patients who had them. 50 isolates were gathered from Peshawar's LRH ICU facilities in the year 2021. The antibiotic susceptibility test was conducted in accordance with the Clinical and Laboratory Standards Institute's standards (CLSI). …

Go to article

First Prev Next Last