Digital Commons Network^™

Mental Disorder In Children With Physical Conditions: A Pilot Study, Alexandra Butler, Ryan J Van Lieshout, Ellen Louise Lipman, Harriet L Macmillan, Andrea Gonzalez, Jan Willem Gorter, Kathy Georgiades, Kathy N Speechley, Michael H Boyle, Mark A Ferro

Paediatrics Publications

Objectives

Methodologically, to assess the feasibility of participant recruitment and retention, as well as missing data in studying mental disorder among children newly diagnosed with chronic physical conditions (ie, multimorbidity). Substantively, to examine the prevalence of multimorbidity, identify sociodemographic correlates and model the influence of multimorbidity on changes in child quality of life and parental psychosocial outcomes over a 6-month follow-up.

Design

Prospective pilot study.

Setting

Two children's tertiary-care hospitals.

Participants

Children aged 6-16 years diagnosed in the past 6 months with one of the following: asthma, diabetes, epilepsy, food allergy or juvenile arthritis, and their parents.

Outcome Measures

Response, …

A Feasibility Trial Of Mental Health First Aid First Nations: Acceptability, Cultural Adaptation, And Preliminary Outcomes, Claire Crooks, Andrea Lapp, Monique Auger, Kim Van Der Woerd, Angela Snowshoe, Billy Joe Rogers, Samantha Tsuruda, Cassidy Caron

Education Publications

The Mental Health First Aid First Nations course was adapted from Mental Health First Aid Basic to create a community-based, culturally safe and relevant approach to promoting mental health literacy in First Nations contexts. Over 2.5 days, the course aims to build community capacity by teaching individuals to recognize and respond to mental health crises. This feasibility study utilized mixed methods to evaluate the acceptability, cultural adaptation, and preliminary effectiveness. Our approach was grounded in Community-Based Participatory Research principles, emphasizing relationship-driven procedures to collecting data and choice for how participants shared their voices. Data included participant interviews (n=89), and surveys …

A Framework For Integrating Implicit Bias Recognition Into Health Professions Education, Javeed Sukhera, Chris Watling

Paediatrics Publications

Existing literature on implicit bias is fragmented and comes from a variety of fields like cognitive psychology, business ethics, and higher education, but implicit-bias-informed educational approaches have been underexplored in health professions education and are difficult to evaluate using existing tools. Despite increasing attention to implicit bias recognition and management in health professions education, many programs struggle to meaningfully integrate these topics into curricula. The authors propose a six-point actionable framework for integrating implicit bias recognition and management into health professions education that draws on the work of previous researchers and includes practical tools to guide curriculum developers. The six …

Disturbed Eeg Sleep, Paranoid Cognition And Somatic Symptoms Identify Veterans With Post-Traumatic Stress Disorder, Harvey Moldofsky, Lorne Rothman, Robert Kleinman, Shawn G. Rhind, Don Richardson

MacDonald Franklin OSI Research Centre

Background

Chronic post-traumatic stress disorder (PTSD) behavioural symptoms and medically unexplainable somatic symptoms are reported to occur following the stressful experience of military combatants in war zones. Aims

To determine the contribution of disordered EEG sleep physiology in those military combatants who have unexplainable physical symptoms and PTSD behavioural difficulties following war-zone exposure. Method

This case-controlled study compared 59 veterans with chronic sleep disturbance with 39 veterans with DSM-IV and clinician-administered PTSD Scale diagnosed PTSD who were unresponsive to pharmacological and psychological treatments. All had standardised EEG polysomnography, computerised sleep EEG cyclical alternating pattern (CAP) as a measure of sleep …

Mathematical Abilities In Children With Developmental Language Disorder, Alexandra M. Cross, Lisa M.D. Archibald, Marc F. Joanisse

Health and Rehabilitation Sciences Publications

Purpose. The present paper provides a scoping review of the literature on mathematical abilities in developmental language disorder (DLD). Children with DLD typically struggle with learning in school, however the mechanism by which DLD impacts academic success is unclear. Mathematics involves demands in the multiple domains, and therefore holds potential for examining the relationship between language and academic performance on tasks mediated by verbal and non-verbal demands.

Methods. A scoping review was performed via computerized database searching to examine literature on mathematics and DLD. The 21 papers meeting inclusion criteria compared children with typical development or DLD on various tasks …

Maturation In Auditory Event-Related Potentials Explains Variation In Language Ability In Children., Elaine Yuen Ling Kwok, Marc F Joanisse, Lisa Archibald, Margot E. Stothers, Heather M Brown, Janis Oram Cardy

Health and Rehabilitation Sciences Publications

Processing of auditory information in the cortex continues to develop into later childhood and adolescence. Recent research has indicated that intraclass correlation (ICC) is the best method for capturing maturation in auditory event-related potentials (AEPs) of school-age children. However, the sensitivity of the ICC approach in discerning AEP changes in children has not been consistently demonstrated and positive results have not been replicated. We attempted this replication and further explored whether AEP maturation estimated using the ICC approach predicts cognitive and linguistic abilities in addition to chronological age. We measured AEPs in response to simple tones in groups of 7-, …

Universality Of Egoless Behavior Of Software Engineering Students, Pradeep Waychal, Luiz Fernando Capretz

Electrical and Computer Engineering Publications

Software organizations have relied on process and technology initiatives to compete in a highly globalized world. Unfortunately, that has led to little or no success. We propose that the organizations start working on people initiatives, such as inspiring egoless behavior among software developers. This paper proposes a multi-stage approach to develop egoless behavior and discusses the universality of the egoless behavior by studying cohorts from three different countries, i.e., Japan, India, and Canada. The three stages in the approach are self-assessment, peer validation, and action plan development. The paper covers the first stage of self-assssment using an instrument based on …

Research Snapshot: Changes In Depression And Positive Mental Health Among Youth In A Healthy Relationships Program, Centre For School Mental Health

Research Snapshots

This study explored and identified meaningful groups of youth based on their depression symptoms over time. Researchers found that youth who reported high levels of depression prior to the program experienced a significant decline in depressive symptoms and improved mental well-being following the program.

Human Neuroimaging Reveals The Subcomponents Of Grasping, Reaching And Pointing Actions., Cristiana Cavina-Pratesi, Jason D Connolly, Simona Monaco, Teresa D Figley, A David Milner, Thomas Schenk, Jody C Culham

Brain and Mind Institute Researchers' Publications

Although the neural underpinnings of visually guided grasping and reaching have been well delineated within lateral and medial fronto-parietal networks (respectively), the contributions of subcomponents of visuomotor actions have not been explored in detail. Using careful subtraction logic, here we investigated which aspects of grasping, reaching, and pointing movements drive activation across key areas within visuomotor networks implicated in hand actions. For grasping tasks, we find activation differences based on the precision required (fine > coarse grip: anterior intraparietal sulcus, aIPS), the requirement to lift the object (grip + lift > grip: aIPS; dorsal premotor cortex, PMd; and supplementary motor area, SMA), …

Cross-Script Orthographic And Phonological Preview Benefits, Olessia Jouravlev, Debra Jared

Brain and Mind Institute Researchers' Publications

The present experiment examined the use of parafoveally presented first-language (LI) orthographic and phonological codes during reading of second-language (L2) sentences in proficient Russian-English bilinguals. Participants read English sentences containing a Russian preview word that was replaced by the English target word when the participant’s eyes crossed an invisible boundary located before the preview word. The use of English and Russian allowed us to manipulate orthographic and phonological preview effects independently of one another. The Russian preview words overlapped with English target words in (a) orthography (ВЕЛЮР [vʲɪˈlʲʉr]–BERRY), (b) phonology (БЛАНК [blank]–BLOOD), or (c) had no orthographic or phonological overlap …

Registered Reports: Introducing A New Article Format In Developmental Science, Daniel Ansari, Judit Gervain

Brain and Mind Institute Researchers' Publications

No abstract provided.

Understanding The Effects Of Education Through The Lens Of Biology, H Moriah Sokolowski, Daniel Ansari

Brain and Mind Institute Researchers' Publications

Early educational interventions aim to close gaps in achievement levels between children. However, early interventions do not eliminate individual differences in populations and the effects of early interventions often fade-out over time, despite changes of the mean of the population immediately following the intervention. Here, we discuss biological factors that help to better understand why early educational interventions do not eliminate achievement gaps. Children experience and respond to educational interventions differently. These stable individual differences are a consequence of biological mechanisms that support the interplay between genetic predispositions and the embedding of experience into our biology. Accordingly, we argue that …

Characterizing Auditory Cortical Receptive Fields, Brainscan , Western University, Ingrid Johnsrude, Alex Billig, Matthew A. Howard Iii, David Steven, Jorge Burneo

Project Summaries

Through this research we have a unique opportunity to explore how auditory cortices respond to naturalistic stimuli and how that response changes with different tasks. This foundational work is critical if we are to understand abnormality in auditory cortices in disorders such as autism, specific language impairment, auditory processing disorders and prolonged auditory deprivation (due to hearing loss).

Imaging Visually-Evoked Cortical Activity, Brainscan, Western University, Blake E. Butler, Stephen Lomber, Kyle Gilbert, Mathias Dietz

Project Summaries

This work will significantly inform our understanding of 'neural plasticity', the ability of the brain to respond and reorganize to environmental changes or following an injury or disorder. It is also our hope that the results of this program will inform the design of devices to restore hearing - it might enable tuning of those devices to restore sensory representations in the brain in a patient-specific manner. We believe this will significantly reduce the impact of cognitive disorders that arise as a result of abnormal perception both in children and in older adults.

System-Wide Electrophysiological Assessment Of Hearing, Brainscan , Western University, Ingrid Johnsrude, Björn Herrman, Chris Allen

Project Summaries

The current work proposes to develop and evaluate an electrophysiological recording setup capable of assessing neural function at all levels of the auditory neural pathway, including hair cells, auditory nerve fibers, brainstem and cortex. We will then test the neural responses across those levels of the auditory pathway in younger and older people.

Neurocognitive, Genetic And Environmental Risk Factors Of Learning Disorders In Children, Brainscan , Western University, Marc Joanisse, Daniel Ansari, Lisa Archibald, Elizabeth Hayden, Janis Oram Cardy, Ryan Stevenson, Jeffrey Gruen

Project Summaries

Our research has already uncovered a range of behavioural and neural factors that can differentiate between children whose development is impaired and those whose development is progressing typically. Intriguingly, our recent findings have also suggested that multiple learning disorders are often present in children with general cognitive difficulties like autism spectrum disorder and ADHD. However, a common feature of research in this area is that of a ‘distinct syndrome’ approach, only studying childhood disabilities separately.

Ommaba: The Open Multimodal Music And Auditory Brain Archive, Brainscan , Western University, Jessica Grahn, Jorn Diedrichsen, Joe Gati, Molly Henry, Robert Zatorre, Jean-Baptiste Poline, Bratislav Misic, Estrid Jakobsen, Mor Regev, Marcel Farrés Franch, Virginia Penhune, Emily Coffey

Project Summaries

We will create a specific neuroimaging database focused on the auditory domain. It will allow researchers to ask questions about the neural circuitry underlying auditory behaviour in the healthy brain and to understand the sources of individual variability. We will include detailed information about experiential factors, such as musicianship and bilingualism that are not documented in any existing databases, so that it will be possible to investigate plasticity-related effects. It will also provide baseline data for clinical studies.

Assessing Listening With Engaging, Real-World Auditory Signals, Brainscan , Western University, Björn Herrmann, Ingrid Johnsrude 6612111

Project Summaries

Our project will develop and evaluate a novel way (using functional imaging, fMRI, and electrophysiology, EEG) to assess this cognitive impact of hearing loss with engaging, real‐world auditory stimuli. We will try to assess listening effort in more realistic listening situations among healthy listeners, comparing detected effort in degraded and clear acoustic conditions.

Using EEG, we will then develop measures that are sensitive to the cognitive demands imposed by degraded speech, using these features to assess hearing function with engaging narratives in natural listening conditions.

The Effect Of Musical Training On Speech And Sound Perception, Brainscan, Western University, Ingrid Johnsrude, Vanessa Irsik, Stephen Van Hedger

Project Summaries

We are going to carry out such a study, in conjunction with research labs at five other institutions. With six universities involved, we will be able to recruit a sufficiently large number of people in the study and decrease the likelihood of any regional bias influencing the outcomes. We will be trying to validate the following claims:

• that musicians have an improved ability to understand speech in noisy environments
• that the responses of a musician's brainstem to speech sounds is enhanced, and
• that older musicians have reduced symptoms from age-related hearing loss.

Attention Bias Modification Training As A Potential Preventative Tool, Brainscan, Western University, Elizabeth Hayden, Marc Joanisse, Pan Liu, Koraly Perez-Edgar, Thomas Olino

Project Summaries

We will use eye-tracking techniques to understand more about attentional bias and how it changes through ABM training.

Through neuroimaging, we will look at 'resting state functional connectivity', which is the activity and communication in the brain when a person is not engaging in any activity themselves. There are resting-state patterns of brain activity that have been identified in the brains of youth with depression, anxiety and related disorders, but we do not know if these brain patterns can be used to identify those at risk for these disorders. We also don't know if preventative approaches to depression and anxiety, …

Validating Methods For Using Noninvasive Brain Stimulation To Influence Auditory Perception, Brainscan, Western University, Jessica Grahn, Molly Henry, Blake Butler, Marc Joanisse, Stefan Everling

Project Summaries

We will be exploring the influence of a weak alternating current on neural activity at different frequencies to build a more complete picture of tACS. We will also incorporate EEG measurements to help us predict how the synchronization varies across individuals, to determine when to provide stimulation for each individual. Finally, we will vary the tACS stimulation and use participant behaviour as the measure to understand what stimulation timing produces the largest behavioural changes.

Familiar Voices Are More Intelligible, Even If They Are Not Recognized As Familiar, Brainscan, Western University, Emma Holmes, Ysabel Domingo, Ingrid Johnsrude

Research Summaries

This research has demonstrated that it’s easier to understand someone who is familiar to us (compared to someone unfamiliar) even if we can’t recognize them from their voice. As listeners, we focus on certain parts of speech sounds for specific purposes. For example, there may be some situations in which you can understand words spoken by your mother very well, better than you could understand a stranger in the same situation, even if you can’t tell that it’s your mother speaking.

Aging Is Associated With An Over-Sensitivity Of Brain Responses To Sounds, Brainscan, Western University, Björn Herrmann, Burkhard Maess, Ingrid S. Johnsrude

Research Summaries

Aging and hearing loss leads to increased neural responses to sounds in the auditory cortex compared to younger people. Enhanced neural activity to sound may be a physiological mechanism underlying the difficulty that older adults have with ignoring irrelevant sound information.

How And Why Strategy Instruction Can Improve Second Language Reading Comprehension: A Review, Deanna Friesen, Corinne A. Haigh

Education Publications

Increasingly, children enter the school system with a home language that differs from the language of the majority. Consequently, classrooms have students with diverse language backgrounds and teachers must develop reading comprehension instruction that meets the needs of all their students. To successfully plan instruction, it is critical for teachers to understand the strengths that second language learners (SLLs) bring to the classroom as well as the potential difficulties they face. Here we review the literature on reading comprehension development and utilize cognitive frameworks to describe the knowledge, skills, and processes involved during reading for meaning. We use these theories …

Cultural Context As A Biasing Factor For Language Activation In Bilinguals, Matthias Berkes, Deanna Friesen, Ellen Bialystok

Education Publications

Two studies investigated how cultural context and familiarity impact lexical access in Korean-English bilingual and English monolingual adults. ERPs were recorded while participants decided whether a word and picture matched or not. Pictures depicted versions of objects that were prototypically associated with North American or Korean culture and named in either English or Korean, creating culturally congruent and incongruent trials. For bilinguals, culturally congruent trials facilitated responding but ERP results showed that images from both cultures were processed similarly. For monolinguals, culturally incongruent pairs produced longer RTs and larger N400s than congruent items, indicating more effortful processing. Thus, an unfamiliar …

Evidence For A Bifactor Structure Of The Scales Of Psychological Well-Being Using Exploratory Structural Equation Modeling, Jose A. Espinoza, John P. Meyer, Brittney K. Anderson, Chelsea Vaters, Christina Politis

Psychology Publications

This research investigates the much-debated factor structure of the 54-item version of Ryff’s (1989) Scales of Psychological Well-being (SPWB). Using two samples (n₁ = 573; n₂ = 449) of undergraduate university students, we apply confirmatory factor analysis (CFA) along with recently developed exploratory structural equation modeling (ESEM) techniques to evaluate several unidimensional and multidimensional models identified in previous research, as well as a new bifactor model. In a bifactor model, items load directly on both a global and a specific factor; when tested using ESEM, cross-loadings on other specific factors are also permitted and are targeted to …

Not The Years In Your Life, But The Life In Your Years: Lessons From Canadian Psychology On Living Fully., David J.A. Dozois

Psychology Publications

Over the past couple of decades, there has been an increasing focus on positive psychology in both the popular media and the scientific literature. Prior to this time, the predominant focus has been on what is aberrant or deficient, and how to ameliorate problems or dysfunction (i.e., a psychopathology orientation). Indeed, my own research has focused on cognitive vulnerability to depression and how we can understand and modify underlying core beliefs and cognitive structures. In this article, I deviate from my own ‘comfort zone’ to highlight some key concepts related to understanding what makes life fulfilling and meaningful. Specific lessons …

Cognitive Change In Cognitive-Behavioural Therapy V. Pharmacotherapy For Adult Depression: A Longitudinal Mediation Analysis, Leanne Quigley, David J.A. Dozois, R. Michael Bagby, Daniela S S Lobo, Lakshmi Ravindran, Lena C Quilty

Psychology Publications

Background Although cognitive-behavioural therapy (CBT) is a well-established treatment for adult depression, its efficacy and efficiency may be enhanced by better understanding its mechanism(s) of action. According to the theoretical model of CBT, symptom improvement occurs via reductions in maladaptive cognition. However, previous research has not established clear evidence for this cognitive mediation model.

Methods The present study investigated the cognitive mediation model of CBT in the context of a randomized controlled trial of CBT v. antidepressant medication (ADM) for adult depression. Participants with major depressive disorder were randomized to receive 16 weeks of CBT (n = 54) or ADM …

Maturation In Auditory Event-Related Potentials Explains Variation In Language Ability In Children, Elaine Y.L. Kwok, Marc F. Joanisse, Lisa M.D. Archibald, Margot E. Stothers, Heather M. Brown, Janis Oram Cardy

Communication Sciences and Disorders Publications

© 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd. Processing of auditory information in the cortex continues to develop into later childhood and adolescence. Recent research has indicated that intraclass correlation (ICC) is the best method for capturing maturation in auditory event-related potentials (AEPs) of school-age children. However, the sensitivity of the ICC approach in discerning AEP changes in children has not been consistently demonstrated and positive results have not been replicated. We attempted this replication and further explored whether AEP maturation estimated using the ICC approach predicts cognitive and linguistic abilities in addition to chronological …

Higher And Lower Order Factor Analyses Of The Temperament In Middle Childhood Questionnaire., Yuliya Kotelnikova, Thomas M Olino, Daniel N Klein, Sarah V M Mackrell, Elizabeth P Hayden

Brain and Mind Institute Researchers' Publications

The Temperament in Middle Childhood Questionnaire (TMCQ) is a widely used parent-report measure of temperament. However, neither its lower nor higher order structures has been tested via a bottom-up, empirically based approach. We conducted higher and lower order exploratory factor analyses (EFAs) of the TMCQ in a large ( N = 654) sample of 9-year-olds. Item-level EFAs identified 92 items as suitable (i.e., with loadings ≥.40) for constructing lower order factors, only half of which resembled a TMCQ scale posited by the measure's authors. Higher order EFAs of the lower order factors showed that a three-factor structure (Impulsivity/Negative Affectivity, Negative …