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A Method For The Determination Of Purity Of Pnu-10483 Bulk Drug By Capillary Zone Electrophoresis, Gavin Gibson

Honors Theses

In this investigation, a method was developed for the determination of purity of the drug PNU-10483 using the technique of capillary zone electrophoresis (CZE). CZE was seen as a potential alternative to the formerly used procedure of ion-pair reversed phase highperformance liquid chromatography (HPLC). Nearly five years earlier, a similar study was performed, in which an attempt was made to develop a method that used CZE to determine the purity of bulk drug and the potency of drug tablets. While this development was mostly successful, sporadically unpredictable results reduced the method's overall viability. These outliers were thought to be caused …

Effects Of Zinc On Glucose-6-Phosphate Dehydrogenase In Buffalo Rat Liver Cells, Bryan G. Sauer

Honors Theses

In recent years, interest has surfaced in the use of insulin-mimicking agents for diabetic therapies. Zinc has been shown to have insulin-like effects in vivo and in vitro but has never been studied for its ability to mimic insulin in the regulation of carbohydrate and fatty acid metabolism. Therefore, the author studied the effects of zinc on glucose-6-phosphate dehydrogenase (G6PDH), an enzyme stimulated by insulin that is imperative in both carbohydrate and fatty acid metabolism. Because G6PDH is highly regulated in liver cells, a stable rat liver cell line, Buffalo Rat Liver (BRL), was used. Endogenous G6PDH activity and G6PDH …

Registration Laws And Their Impact On Voter Retention, Tom Lenard

Honors Theses

The literature on voting participation suggests a number of factors that should affect voter turnout differences including the legal incentives or hindrances acting directly on individual citizens. In this study I examine registration laws and how they may play a role in the stability over voter turnout between presidential and midterm elections. Specifically, this research concentrates on classifying each individual state into groups with easier and those with more strict registration requirements. With this done, I compared the voter turnout for the 1990-1996 elections between the two groups. Also, I looked at the drop-off rates in percentage of turnout for …

Western News, April 9, 1998, Western Michigan University

Western News (1972-2018)

Story highlights: Schedules set for visits by presidential candidates, Haenicke to testify before House subcommittee May 6, Four more chosen as 'named endowed professors', Roberts to give leadership lecture, Paper Tech Foundation announces campaign, Maestro Takeda to serve as artist-in-residence, Full text of President Diether H. Haenicke's "State of the University" address presented on March 31, 1998; at the 18th annual Academic Convocation.

The Effects Of Fasb Statement No. 121 On Financial Statements, Karen Courtade

Honors Theses

As managers contemplate the adoption of SFAS 121, Accounting for the Impairment of Long-Lived Assets and for Long-Lived Assets to be Disposed of, most will be considering the impact of these new requirements on their particular reporting situation. This effect is important to managers because whenever the Financial Accounting Standards Board (FASB) issues a new statement, financial statements need to be in compliance with Generally Accepted Accounting Principles (GAAP). New requirements also cause tax and auditing concerns, effects on financial statement users, and extra costs to companies involved. The FASB's intent in issuing SFAS 121 was to force more …

The Recycling Of Vacuum Formed Products And The Effect On Use Characteristics, Robert J. Miles

Paper Engineering Senior Theses

Vacuum formed products, commonly called molded pulp, are a superb alternative to expanded polystyrene (Styrofoam) in many current packaging applications. This movement from the petroleum based products of the past to innovative new wood fiber based packaging is due to many reasons including economic benefit, environmental stigma, and/or legislative intervention. The current dilemma is dealing with the inherent fiber characteristics, contaminants, and product composition of molded pulp products. As more of these products appear in secondary waste streams, there is a need for information pertaining these parameters. Unfortunately, very little technical information is available due to the high level of …

A Kinematic And Kinetic Analysis Of First, Fourth, And Fifth Positions In The Classical Ballet Method, Mary Sue Hill

Masters Theses

The problem of the study was to compare electromyography (EMG) responses, ground reaction forces, and torques on female college-age dancers' knees in selected positions. Subjects were 18 female dancers, aged 18 to 30 years, with 6 subjects from each of three levels: Ballet Technique I, II, and III. The rectus femoris, vastus lateralis, and vastus medialis were analyzed in a grande plie in three positions, (1) first, (2) fourth, and (3) fifth, with two phases: (1) eccentric, and (2) concentric. No differences in force or EMG data were found for the concentric phases of the three positions. Significant differences were …

The Western Michigan University Magazine, Spring 1998, Western Michigan University

Western Michigan University Magazine (1997-present)

Features

• Making the Difference: Retiring President Diether Haenicke leaves a legacy of pride, progress and heightened ambition.
• Shedding Light on the Secrets of Physics: Focus and intensity make researcher Nora Berrah a success while helping undergrads do research.
• World-Class Jazz Entertainment: Gold Company, WMU's award-winning vocal jazz group, turns 20 with a bang.
• What I Have Seen: A light look back at the Haenicke years, with apologies to Dr. Seuss.

Sections

• University News
• College News
• Classnotes
• Obituaries
• Athletic News

The Effect Of Caffeine On Reaction Time, Hand Steadiness, And Certain Physiological Variables, Amy K. Ryan

Masters Theses

The problem of this study was to analyze the effect of caffeine on heart rate, blood pressure, reaction time, and hand steadiness. Subjects (N = 20) were classified as high-caffeine users or low-caffeine users. Heart rate, blood pressure, reaction time, and hand steadiness were measured. Subjects then consumed 24 oz of coffee containing 345 mg of caffeine in a 5-min period. Dependent variables were measured again at 30, 60, and 90 min after caffeine administration. Significant differences were found among test time means for every dependent variable except hand steadiness. No difference was found between the high-caffeine-use group and the …

Effects Of The Prbar And Powerbar On Fat Metabolism, Chad F. Witt

Masters Theses

The purpose was to compare the effect of dietary supplementation using two different energy bars, the PRBar and the PowerBar, ingested 1 hour before exercise, on the exercise metabolism of endurance athletes. Four dependent variables were measured: respiratory exchange ratio (R), oxygen consumption (VO₂), rating of perceived exertion (RPE), and blood glucose. Independent variables were bars (2), trials (2), and sample time. Sample times occurred at 5-min intervals for R, VO₂, and RPE. Blood glucose was sampled before exercise, at 15 min and 25 min during exercise, and after exercise. Subjects completed four 35-min training runs, …

The Relationship Of Saudi Managers’ Characteristics And Their Support Of The Transfer Of Training To The Workplace, Khalid M. Alhazmi

Dissertations

Many HRD professionals have pointed out that one of the most important elements for transfer of training to the workplace is management support. However, there is little discussion concerning management characteristics that support the transfer of training to the workplace. The purpose of this study was to investigate management characteristics that inhibit or promote the transfer of training to the workplace and to provide information regarding those characteristics to companies.

This study focused on one main question: Do management characteristics have an effect on management support of the transfer of training to the workplace? To answer this question, a study …

Community Leaders’ Perceptions Of Violence Against Women As A Public Health Issue, Deborah J. Bartz

Masters Theses

The purpose of this thesis was to identify correlates of support for the involvement of local public health departments in the prevention of violence against women. The research is a secondary analysis of data from community leaders in the 50 public health catchment areas throughout Michigan.

A total of 525 community leaders were identified by health officers and were mailed surveys that dealt with a wide range of health policy issues. Three hundred and fifty-one surveys were returned.

The analysis were designed to determine which factors would affect support for treating violence against women as a public health issue. A …

The Effects Of Music Therapy On The Self-Esteem And Locus Of Control Of Children Survivors Of Domestic Violence, Amy A. Bogetto

Masters Theses

The purpose of this study was to measure the effects of a volunteer music therapy program on the self-esteem and locus of control of children survivors of domestic violence residing in a shelter for domestic violence. An experimental group which received music therapy and a no-contact control group were used in this study. The Coopersmith Self-Esteem Inventory Scale was used to measure the subjects' selfesteem while the Nowicki-Strickland Locus of Control scale was used to measure the subjects' locus of control in both groups. These tests were administered before and after treatment for the experimental group. The control group was …

Assessing Child Care Need In Niles, Michigan, Lori L. Mcneil

Masters Theses

Many parents struggle to secure adequate child care while they work and/or attend school. With the passage of welfare reform legislation, which in part requires AFDC parents to enter/reenter the workforce, locating child care options will likely become increasingly more difficult.

This study describes child care needs of one community based on a survey of parents at thirteen different sites. The research measured the discrepancy between existing child care resources and child care demand within the community.

Analysis of the data revealed that the ways in which parents provide care for their children differed considerably in Niles from the most …

Prostitution In U.S. Society: Moving Beyond Traditional Feminist Frameworks Of Analysis, Megan M. Coats

Masters Theses

In this thesis, I explore the different ways that prostitute women's voices have been silenced by groups which have historically controlled the social and academic discourse on prostitution. Utilizing the research method of standpoint epistemology, I first discuss why the prostitute activist's voices must be considered as the central source for scientists theorizing on prostitution. Next, I give an account of some historical influences which have shaped the discourse on prostitution, affecting the development of legislation regulating prostitution. Then, I provide a history of the development of the liberal and radical feminist discourse on prostitution. I also include some contemporary …

The Social Diffusion Of Safe Sex Behaviors In College Women, Sherry Pagoto

Masters Theses

With the ever rising numbers of people becoming infected with the human immunodeficiency virus (HIV) as reported by the Centers for Disease Control (CDC, 1997) the need for preventing the spread of infection is clear. One promising intervention, based on a theory called social diffusion, involves training popular opinion leaders to act as behavior change endorsers within their community (Kelly, 1991). This study found 25-30% reductions in high-risk behaviors and 16-18% increases in safe sex behaviors in a male homosexual population as a result of this type of intervention. The current study examines the effectiveness of this intervention within a …

The Role Of The Parish Pastor As Mental Health Provider: Counseling Competency And Personality Characteristics, John Phillip Burgess

Dissertations

United Methodist pastors, serving churches in the State of Michigan, were surveyed regarding their participation in counseling and referral to other mental health providers. In addition to a demographic questionnaire, each pastor completed two standardized instruments, the Counseling Self-Estimate Inventory (COSE) (Larson, et al., 1992) and the Edwards Personal Preference Schedule (EPPS) (Edwards, 1959). Dependent variables of amounts and types of counseling being conducted, scores from the COSE and EPPS, and four satisfaction ratings, were compared across several independent variables including: pastor's gender, age, race, length of service, theological orientation, and amount of academic preparation specifically related to mental health/counseling …

A Study Of Local-Cosmopolitan Orientation With A University Support Staff, Sharon Carr

Dissertations

The purpose of this study is to identify the local-cosmopolitan orientation of a subset of university support staff members and to examine the relationship between that orientation and (a) gender, (b) age, (c) years of service, (d) percentage of business/financial tasks in one’s job, (e) percentage of time spent in direct contact with students, and (f) the self-perception of how essential one’s job is to the mission of the university. The local-cosmopolitan concept used was based on the definition by Qouldner (1957) and includes his three elements: loyalty, operational style, and reference group use. Each one of these elements, as …

Health Care Beliefs Of Nursing Students As Predictors Of Intentions To Care For A.I.D.S. Patients, Catherine Ellen Earl

Dissertations

The purposes of this study were (a) to determine if information about AIDS taught using two different formats, lecture discussion and video discussion, results in differential retention of content about AIDS; (b) to determine if health care beliefs about AIDS change after exposure to a lecture or a video about AIDS among first year nursing students in rural community colleges; and (c) to examine whether the differences in intentions to provide care for AIDS patients are associated with health care beliefs about AIDS. In this study, both qualitative and quantitative research methods were used. The study was conducted over two …

Direct Service Staff's Perceptions Of Psychotropic Medication In Noninstitutional Settings For Individuals With Developmental Disabilities, Leeann Christian

Dissertations

Approximately 35-55% of individuals with mental retardation who live in the community are prescribed psychotropic and/or antiepileptic medication (Aman, Saphare, & Burrows, 1995; Singh, Guernsey, & Ellis, 1992). As more individuals with severe behavior challenges are transitioned from institutions into the community, these rates are likely to increase. Given these prevalence rates, it is important to determine whether staff who serve people with mental retardation are adequately educated about psychotropic medications. Previous studies (Aman, Singh, & White, 1987; Gadow, 1983; Singh, Epstein, Stout, Luebke, & Ellis, 1994; Singh et al., 1996) surveyed a variety of service providers in school and …

African-American Females And The Glass Ceiling In The Defense Logistics Agency, Velma Lee Clay

Dissertations

This study explores the career advancement experiences of African American women who have successfully broken through the glass ceiling. The term “glass ceiling” refers to artificial or invisible barriers based on attitudinal or organizational bias that prevent qualified women and minorities from advancing into senior-level management positions. Studies have confirmed that a glass ceiling does exist for African American women and that they are severely underrepresented in top level government jobs, they have less opportunity for advancement, and both gender and race are perceived as factors in their limited representation (MSPB 1992).

What is the Impact of Breaking the Glass …

Groundwater Hydraulics And Slope Stability Analysis: Elements For Prediction Of Shoreline Recession, William W. Montgomery

Dissertations

Studies documenting the roles that geologic materials and groundwater play in Great Lakes bluff recession are rare. This study reports findings concerning relationships between bluff lithology, bluff hydrology, and bluff recession along a 10-mile stretch of eastern Lake Michigan shoreline in heterogeneous Pleistocene deposes. According to a newly-developed, field-tested, GIS-based methodology, bluffs in the study area can be characterized lithologically as sand, clay, or mixed sand/clay, and can be characterized hydrologically as exhibiting either high head or low head.

Geotechnical analysis indicates that Atterberg limits, index properties, consolidation state, and drainage conditions affect the shear strength of bluff materials. Silty …

Implications Of Changing To 4 By 4 Semester Block Scheduling For Secondary Students With Learning Disabilities, Sandra Kay Wayne

Dissertations

The purpose of this study was to investigate the impact of changing from a traditional schedule to a block schedule on selected school-related behaviors and measures of secondary students with learning disabilities and their regular education teachers. Areas of impact that were addressed included school performance measures of student success rates, attendance rates, and discipline referrals as well as affective measures of levels of students' active engagement in learning activities, the variety of teaching and learning modes used, and the amount of individualized teacher attention given to students.

The research population consisted of six high schools in south and central …

An Analysis Of Fecal Coliform Bacteria As A Water Quality Indicator, Janet Heyl Vail

Dissertations

The focus of this study is to assess the efficacy of fecal coliform bacteria as a microbiological water quality indicator. The scientific and educational context of fecal coliform bacteria is explored through analysis of large sets of water quality data, focused field monitoring projects, and review of commonly used resources for school-based and volunteer water-related studies. Analyzed data sets include long term sampling (10 years), multiple sites, daily samples, storm event samples, and other parameters monitored in parallel with bacteria. Special attention is given to data sets from Kent County, Michigan. A background reference site in Michigan unimpacted by humans …

The Relationship Between Leadership/Followership In Staff Nurses And Employment Setting, Elaine S. Vandoren

Dissertations

This study tested the hypothesis that staff nurses in hospitals used different leadership and followership behaviors than staff nurses in home care settings. Leadership behaviors were measured using the Multifactor Leadership Questionnaire (Bass, 1995); followership was measured using Kelley’s Followership Style Questionnaire (1992). Three hospital and home care agencies belonging to a private nonprofit corporation in the Midwest provided data. A total of 136 surveys were used in data analysis; 57% of distributed surveys were returned.

Differences between the hospital and home care staff nurses were not found. Self-perception, difficulty in applying clinical behaviors to the MLQ, unknown aspects of …

The Reliability Of Emg Normalization Procedures For Three Muscles Involved In Knee Extension, James John Sweet

Masters Theses

Analyses of 3 knee extensors, vastus medialis, rectus femoris, and vastus lateralis, were conducted to examine the reliability of (a) maximal voluntary isometric contraction (MVIC) across trials (2), days (5), and joint angles (5); and (b) normalized EMG responses during dynamic knee extension at 2 submaximal work loads. Strength (cable tension) and integrated peak EMG (surface electrodes) were measured during the MVIC. Subjects (N = 44) performed 2 consecutive MVICs with 2 min rest between trials at 110°, 90°, 70°, 50°, and 30° of knee flexion, followed by 2 submaximal dynamic knee extension exercises. Intraclass correlation (R) values for the …

The Effects Of Step Height, Cadence, And Choreography On Biochemical Factors In Step Aerobics, Stacie Moore

Masters Theses

The problem of the study was to determine the effect of step height, speed, and choreography on ground reaction forces, electromyography of the knee extensors, and center of gravity displacement in step aerobics. Two step heights, 6 and 8 in.; two speeds, 126 and 132 bpm; and three steps, basic step, tum step, and hop step, were studied for a single subject across 5 trials. The muscles studied included the rectus femoris, vastus lateralis, and vastus medialis. Results indicated: (a) significant difference existed between the cadences as well as between the step heights for the sagittal plane center of gravity; …

Spatial And Ethnic Patterns Of Real Estate Control Affecting Upward Mobility Of Immigrants In A Nineteenth Century Industrial Community, Debra S. Alfonso

Masters Theses

The subject of immigrant success has previously been analyzed in the context of ethnic characteristics, individual heroism, worker solidarity, and advancement of industrialization. Most immigrants start at the bottom of the social-economic ladder. The mechanisms of advancement vary depending on both ethnic values and the constraints of the socioeconomic system. The key variable is normally thought to be advancing occupational status.

The problem addressed is how did recent immigrants to a 19th century steel-town obtain home ownership and advancement in spite of declining industrial wages. Using a GIS system to link and analyze geographic and historical records I was able …

The Foucault Panopticon Model In Motion: The Internet As A Candidate For Corporate Abandon, Thomas Wells Brignall

Masters Theses

The possible negative impacts the Internet could have on our society, because of its powerful observation potential is the topic of this thesis. In my work I deconstruct several historical and current texts on the Internet. I then critique modern cultural constructs of the Internet and compare and contrast using historical as well as meta-analysis to dissect the real from the simulated.

I have found that a majority of the Internet's current construction lies in the hands of private companies. In my finding, using historical analysis of previous company policies that the potential to observe, track, and keep large databases …

The Effect Of Unloading Body Weight During Aerobic Exercise On Blood Pressure, Heart Rate, And Perceived Exertion, Carolynn J. Bolander

Masters Theses

The problem of the study was to examine the blood pressure, heart rate, and rating of perceived exertion of asymptomatic, active individuals during submaximal treadmill exercise while using an unloading system. Two levels of unloading, 20% unloaded body weight (UBW) and 40% UBW, were compared to 0% UBW. Treadmill speed was determined by the speed required to reach a steady state heart rate of 70% of maximum heart rate in an unloaded state. Twenty subjects, between the ages of 18 and 42 years, served as subjects. Subjects were grouped with respect to fitness level; walkers were those subjects who walked …