Digital Commons Network^™

Autonomous And Non-Autonomous Requirements For The C-Jun N-Terminal Kinase Signaling Pathway In Early Forebrain Development, Jessica G. Cunningham

Graduate Theses, Dissertations, and Problem Reports (ETD)

The cerebral cortex is responsible for a wide variety of high-level functions including cognition, sensory perception, fine motor control, and the orchestration of body movements. The cortex is comprised of cortical excitatory neurons and inhibitory interneurons, which are arranged in a highly organized fashion into different layers and regions. These two types of cells operate in a delicate balance between excitation and inhibition, which is critical for proper cortical circuitry. In order for the cortex to execute its numerous functions, it must both send and receive input to other brain regions through axonal connections. The organization within the cortex and …

Raising Awareness Of Second Victim Phenomenon And Supportingyou: A Quality And Safety Initiative, Megan Renee Bryant

Graduate Theses, Dissertations, and Problem Reports (ETD)

Current literature has established a need for practice change in management of healthcare-related critical incidents. Peer-support programs have been cited as the most impactful resource healthcare professionals request following a critical incident (Daniels & McCorkle, 2016). SupportingYOU, a peer-support program, is in the process of expansion at a large academic children’s hospital in northern West Virginia in anticipation for the opening of a new facility. The specific aim of this project was to raise awareness of second victim phenomenon (SVP), SupportingYOU, and perception of awareness of resiliency. Interventions included multi-formatted educational sessions on SVP and SupportingYOU via PowerPoints, brochures, flyers, …

Noise Exposure Trends Among Violating Coal Mines, 2000 To 2021, Hanna Grace Davis

Graduate Theses, Dissertations, and Problem Reports (ETD)

Noise-induced hearing loss has continued to be a significant issue within the mining industry, even after the passing of the MSHA’s improved noise standard in 2000. NIOSH has recognized that the noise standard enacted by both MSHA and OSHA does not properly protect workers with the 5 dBA exchange rate (i.e., the increase in noise level leading to a doubling of energy) and the lack of emphasizing the use of engineering controls over administrative controls and overreliance on hearing protection device usage. The primary objective of this study is to investigate statistical sound relationships between MSHA noise-related violations and samples …

Living On The Edge: Trans* Exclusion, Survival, And Resistance, Rayna E. Momen

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

This dissertation focuses on the criminalization and victimization of transgender people, broadly defined as people whose gender identity does not align with their assigned birth sex, using a queer criminological and intersectional lens. The introduction offers background and context for this examination, and includes the purpose, theoretical approach, methodology, research questions, contributions, and overviews of the substantive chapters. Chapter two explores what we know and what we do not know about transgender people’s pathways into the criminal legal system, how they experience state surveillance, and how they navigate the system. Chapter three explores violence against transgender people in various …

The Dances Of Diplomacy: French Social Dance Culture In The United States, 1780-1800, Kaylar Gina Moser

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis explores how social dancing in the United States formed a noteworthy aspect of political, diplomatic, social, and class exchange for U.S. elites both domestically and overseas; and how the cultural dominance over dance that France enjoyed during this period created an informal cultural diplomatic relationship between the United States and France in the 1780s and the 1790s. I argue that U.S. elites utilized this dance culture as a form of upper-class status legitimation that could serve diplomatic purposes. This project increases the purview of U.S. cultural diplomatic studies by centering on the eighteenth century and by utilizing an …

Microwave Enhanced Electron Energy Distribution Functions, John Samuel Mckee

Graduate Theses, Dissertations, and Problem Reports (ETD)

The use of two (or more) radio frequency (RF) sources at different frequencies is a common technique in the plasma processing industry to control ion energy characteristics separately from plasma generation. A similar approach is presented here with the focus on modifying the electron population in argon and helium plasmas. The plasma is generated by a helicon source at a frequency f0 = 13.56 MHz. Microwaves of frequency f1 = 2.45 GHz are then injected into the helicon source chamber perpendicular to the background magnetic field. The microwaves damp on the electrons via R-mode (anti-parallel to the background magnetic field …

The Impact Of Formation And Fracture Properties Alternations On The Productivity Of The Multi-Stage Fractured Marcellus Shale Horizontal Wells., Dalal Aldbayan

Graduate Theses, Dissertations, and Problem Reports (ETD)

As the reservoir deplete, the pore pressure decreases and the effective stress increases. The increase in the effective stress results in the formation compaction which can alter the formation and hydraulic fracture properties. This is particularly significant for a Marcellus shale horizontal well with multi-stage hydraulic fracture due to low Young's modulus and moderate Poisson's ratio of the Marcellus shale. The degree of the effective stress increase depends on the initial productivity of the well, which is influenced by the hydraulic fracture properties, formation properties, as well as the operating conditions. Therefore, it is necessary to couple the geomechanical and …

Characterizing Locomotor Disturbance Perception In Young Adults, Daniel James Liss

Graduate Theses, Dissertations, and Problem Reports (ETD)

Falls during walking are a leading cause of injuries across aging. Many of these falls are due to slips and trips. The ability to perceive disturbances to ongoing motion may play an important role in the control of walking balance. However, disturbance perception has been investigated in standing balance, but its role in walking balance due to slip- and trip-like disturbances remains largely unknown. Characterizing locomotor disturbance perception in young adults may lead to a more comprehensive understanding of sensorimotor walking balance control.

This work defined locomotor disturbance perception in response to slip and trip-like disturbances in young adults. We …

A Case Study Of Poland Regarding The Utility Of Strategic Culture, Christian Pierce Griffith

Graduate Theses, Dissertations, and Problem Reports (ETD)

From the Cold War until today, researchers and strategists have worked to find better ways of understanding the strategic decisions of other countries. Many diplomats and international decision makers subscribed to the idea that countries always acted rationally with a rational, cost-benefit analysis approach to problems that laid before them. Others, however, wished to explain the seemingly irrational actions countries have taken, and proposed that not all countries share the same objective values and goals. Academic authors and political strategists claimed that countries have Strategic Cultures, defined as frameworks that policy makers operate within where they are influenced by cultural …

The Burning Bush: Linking Lidar-Derived Shrub Architecture To Flammability, Michelle S. Bester

Graduate Theses, Dissertations, and Problem Reports (ETD)

Light detection and ranging (LiDAR) and terrestrial laser scanning (TLS) sensors are powerful tools for characterizing vegetation structure and for constructing three-dimensional (3D) models of trees, also known as quantitative structural models (QSM). 3D models and structural traits derived from them provide valuable information for biodiversity conservation, forest management, and fire behavior modeling. However, vegetation studies and 3D modeling methodologies often only focus on the forest canopy, with little attention given to understory vegetation. In particular, 3D structural information of shrubs is limited or not included in fire behavior models. Yet, understory vegetation is an important component of forested ecosystems, …

Exploration Of Intercollegiate Student-Athletes’ Athletic Identity, Leah C. Oldham

Graduate Theses, Dissertations, and Problem Reports (ETD)

Student-athletes encounter experiences that can cause their identity process and self-concept to be disturbed. Even though athletic identities are strong among intercollegiate athletes, some encounter identity-threatening events that interrupt their identity process, negatively affecting their athletic identity. The present study adds to current research on the athletic identity of student-athletes by examining the athletic identity and self-esteem of student-athletes to determine if a redshirt season is a positive (identity-enhancing) or negative (identity-threatening) event. The intersectionality of age, race, gender, and ethnicity are examined to understand if multiple identities influence the experience of a redshirt season. Results reveal that a redshirt …

Artificial Intelligence Based Approach For Rapid Material Discovery: From Chemical Synthesis To Quantum Materials, Robert Tempke

Graduate Theses, Dissertations, and Problem Reports (ETD)

With the advent of machine learning (ML) in the field of Materials Science, it has become obvious that trained models are limited by the amount and quality of the data used for training. Where researchers do not have access to the breadth and depth of labeled data that fields like image processing and natural language processing enjoy. In the specific application of materials discovery, there is the issue of continuity in atomistic datasets. Often if one relies on experimental data mined from literature and patents this data is only available for the most favorable of atomistic data. This ultimately leads …

Improving Robotic Decision-Making In Unmodeled Situations, Nicholas Scott Ohi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Existing methods of autonomous robotic decision-making are often fragile when faced with inaccurate or incompletely modeled distributions of uncertainty, also known as ambiguity. While decision-making under ambiguity is a field of study that has been gaining interest, many existing methods tend to be computationally challenging, require many assumptions about the nature of the problem, and often require much prior knowledge. Therefore, they do not scale well to complex real-world problems where fulfilling all of these requirements is often impractical if not impossible. The research described in this dissertation investigates novel approaches to robotic decision-making strategies which are resilient to …

Development And Validation Of Individual-Tree Growth And Mortality Models For Mixed Species Forests Of The Allegheny Plateau Region, Matt C. Marsh

Graduate Theses, Dissertations, and Problem Reports (ETD)

Forest management is a complex task that influences future site conditions for centuries. Therefore, forest managers utilize decision tools such as forest growth and yield models to aid in the decision-making process. These models allow managers to make reasonable assessments about future site conditions and to construct evidence-based management plans. SILVAH, which stands for SILViculture of Allegheny Hardwoods, is a decision tool for forest managers in Central Appalachia and was built by the U.S. Forest Service. It contains a growth and yield simulator that was developed in the late 20^th century. This research sought to understand …

Modeling Nonlinear Dynamic Systems Using Bss-Anova Gaussian Process, Kyle Matthew Hayes

Graduate Theses, Dissertations, and Problem Reports (ETD)

Nonlinear dynamic systems are some of the most common variety of systems encountered in the sciences, but are the potentially more onerous to model through system identification than static systems due to their added complexity, sensitivity to initial conditions, and the potential application of new dynamic and nonlinear behavior through any time dependent forcing functions. The BSS-ANOVA Gaussian Process is a Machine Learning method for dynamic system ID that possesses several attributes that make it a natural candidate for this variety of problem. BSS-ANOVA is fully Bayesian, works best for continuous tabular datasets, and fast training and inference times and …

Polarization Properties Of Millisecond Pulsars: Astrophysical Interpretations And Applications, Haley Megan Wahl

Graduate Theses, Dissertations, and Problem Reports (ETD)

Pulsars are some of the most extreme objects in the universe; their small yet incredibly predictable spin periods coupled with their strong magnetic fields make them ideal laboratories for study. Not only are they interesting objects themselves, but they can also help us probe different astrophysical environments, such as the interstellar magnetic field and the solar corona.

These stars are highly polarized, and that polarization comes into play in various fields of pulsar physics (such as constraining models of pulsar emission), but obtaining that polarization information can be difficult, as the polarization properties of the light can change as the …

Modeling And Optimization Of A Novel Chilled Ammonia Absorption Process And Amine-Appended Metal-Organic Frameworks For Co2 Capture, Ryan Keith Hughes

Graduate Theses, Dissertations, and Problem Reports (ETD)

Post-combustion capture is one of the leading technologies for CO₂ abatement from anthropogenic sources which have contributed significantly to the rise of atmospheric greenhouse gases. Specifically, solvent-based capture post-combustion processes are the industry standard but can suffer drawbacks such as high energy penalties and corrosion. In this work, two possible improvements are investigated which have been recently proposed in the literature. The first is aqueous ammonia as a capture solvent which has been shown to have several advantages including, but not limited to, a lower regeneration energy. The second is a novel solid sorbent, an amine-appended metal-organic framework (MOF). …

Incentive Analysis Of Blockchain Technology, Rahul Reddy Annareddy

Graduate Theses, Dissertations, and Problem Reports (ETD)

Blockchain technology was invented in the Bitcoin whitepaper released in 2008. Since then, several decentralized cryptocurrencies and applications have become mainstream. There has been an immense amount of engineering effort put into developing blockchain networks. Relatively few projects backed by blockchain technology have succeeded and maintained a large community of developers, users, and customers, while many popular projects with billions of dollars in funding and market capitalizations have turned out to be complete scams.

This thesis discusses the technological innovations introduced in the Bitcoin whitepaper and the following work of the last fifteen years that has enabled blockchain technology. A …

A Novel Computational Network Methodology For Discovery Of Biomarkers And Therapeutic Targets, Qing Ye

Graduate Theses, Dissertations, and Problem Reports (ETD)

Lung cancer has the second highest cancer incidence rate and the top cancer-related mortality worldwide. An estimate from the American Cancer Society shows that, in 2022, there will be about 236,740 lung cancer cases (117,910 men and 118,830 women) in the US. To date, there are no prognostic/predictive biomarkers to select chemotherapy, immunotherapy, and radiotherapy in individual non-small cell lung cancer (NSCLC) patients. There is an unmet clinical need to identify patients with early-stage NSCLC who are likely to develop recurrence and to predict their therapeutic responses. This dissertation developed a novel computational methodology for modeling molecular gene association networks …

Bacterial Contamination In Public Atac-Seq Data And Alignment-Free Detection Methods, Drake Michael Aesoph

Graduate Theses, Dissertations, and Problem Reports (ETD)

ATAC-seq is a new high-throughput sequencing technology for measuring chromatin accessibility within genomic samples. It can be used to discover new information about open regions, nucleosome positions, transcription factor binding sites, and DNA methylation. It is especially useful when combined with other next-generation sequencing techniques, such as RNA-seq. Unlike previous technologies, however, ATAC-seq is more sensitive to bacterial contamination, which is a well-known problem in cell cultures that can lead to incorrect experimental results. Previous studies have measured the contamination in public RNA-seq data and found that 5%- 10% of samples were contaminated. In this report, we investigate the prevalence …

Ear Biometrics: A Comprehensive Study Of Taxonomy, Detection, And Recognition Methods, Susan Awm El-Naggar

Graduate Theses, Dissertations, and Problem Reports (ETD)

Due to the recent challenges in access control, surveillance and security, there is an increased need for efficient human authentication solutions. Ear recognition is an appealing choice to identify individuals in controlled or challenging environments. The outer part of the ear demonstrates high discriminative information across individuals and has shown to be robust for recognition. In addition, the data acquisition procedure is contactless, non-intrusive, and covert. This work focuses on using ear images for human authentication in visible and thermal spectrums. We perform a systematic study of the ear features and propose a taxonomy for them. Also, we investigate the …

Love At First Profile: An Experiment Exploring If Previously Incarcerated Individuals Are Less Desirable While Online Dating, Carina L. Perrone

Graduate Theses, Dissertations, and Problem Reports (ETD)

Incarceration is a rapidly increasing occurrence in the United States with more than 1.4 million people incarcerated and more than 2 million on some form of restricted confinement. While men are incarcerated at a much higher rate than women, women are still at a steady incline of incarceration as well. Also, people of color disproportionately make up a large number of those incarcerated while accounting for a small percentage of the general population. Previous research on people who have been incarcerated focuses on it affects education, employment, and marriage. Little research has attempted to explore how incarceration effects dating, a …

Tumor-Targeted Ph-Sensitive Manganese Oxide Nanoparticle For Enhanced Detection Of Breast Cancer Using Mri, Celia Martinez De La Torre

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the United States, approximately 287,850 new cases of invasive breast cancer will be diagnosed, and over 43,000 women will die because of it in 2022. Currently, mammography is the gold standard for breast cancer surveillance. Although this detection technique is relatively cheap and fast, it misses about 1 in 5 breast cancers in younger women with dense breast tissue, causing a delay in treatment. Compared to mammography, magnetic resonance imaging (MRI) has superior soft-tissue contrast that elucidates structural differences within soft tissue to detect more breast cancers. However, MRI still misses

NEMO particles were produced by synthesizing manganese oxide …

Comparison Of Maintenance Cost Of Medium And Heavy-Duty Alternative Fuel And Diesel Vehicles, Isaac C. Boyce

Graduate Theses, Dissertations, and Problem Reports (ETD)

Abstract

Comparison of Maintenance Cost of Medium and Heavy-Duty Alternative Fuel and Diesel Vehicles

Isaac Boyce

This study was conducted to provide an in-depth analysis of the differences in maintenance cost with the use of alternative fuel and diesel in medium (MD) and heavy-duty (HD) vehicles. With the push toward lower emissions from transportation vehicles for a cleaner future, the United States of America (US) has incentivized the conversion from the use of conventional fossil fuel, diesel, to lower carbon alternatives. With the increased potential for the use of alternative fuels, an investigation is warranted to understand the differences. This …

Development Of A Machine Learning Model To Characterize The Performance Of A Selective Catalytic Reduction On Filter After-Treatment System For A Heavy-Duty Diesel Engine, Samuel A. Okeleye

Graduate Theses, Dissertations, and Problem Reports (ETD)

Particulate matter (PM) and Oxides of Nitrogen (NOx) are the major pollutants in diesel engines, an attempt to control one leads to an increase in the other, a phenomenon known as PM-NOx trade-off in diesel engine emission control. Currently, these two pollutants are controlled by the Diesel Particulate Filter (DPF) and the Selective Catalytic Reduction (SCR) after-treatment system respectively, in addition to the Diesel Oxidation Catalyst (DOC) which helps to provide 1:1 split of NO/NO₂ and helps with raising exhaust gas temperatures. Today, heavy-duty diesel engines feature a DPF, a primary SCR and a secondary SCR. Despite this complex …

The Musashi Rna Binding Proteins Are Regulators Of Alternative Splicing And Protein Expression In Photoreceptor Cells, Fatimah Kh. Matalkah

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Musashi (Msi) family of RNA binding proteins consists of two paralogs, Msi1 and Msi2, that are highly conserved across species. The two paralogs have emerged as factors that promote stem cell proliferation by post-transcriptionally regulating translation. In addition to their expression in stem cells, the Musashi proteins are also expressed in postmitotic neurons, including the photoreceptor cells. The Musashi proteins have been observed to maintain high expression levels in the postmitotic photoreceptors within the eye of both invertebrates and vertebrates. These observations suggest an additional role in the maintenance of terminally differentiated neurons.

Building upon these observations, we investigated …

Developing Teaching Adaptability In Pre-Service Teachers Using Practice-Based Teacher Education, Kyuil Cho

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to examine how pre-service teachers (PSTs) develop their teaching adaptive competence through teaching rehearsal and repeated teaching, which is one of the focused teacher education strategies in practice-based teacher education (PBTE). This study was conducted in an introductory teaching methods course of a physical education teacher education (PETE) program. A total of 22 PSTs participated in the study. Fourteen were male, and eight were female. The PSTs had varied coaching experiences ranging from little to no coaching in limited recreational sports settings, and none had teaching or coaching experience in the school setting.

A …

Decentralized Cooperative Localization For Multi-Robot Systems In Challenging Environments, Eduardo Gutierrez

Graduate Theses, Dissertations, and Problem Reports (ETD)

Multi-robot systems provide more adaptability and robustness than conventional single-robot systems. This is because they have the ability to achieve partial completion of a task in the presence of failures due to the intrinsic inclusion of non-single-point failure. In multi-robot systems, cooperative localization refers to the use of relative measurements to improve the group’s overall localization performance. While centralized architectures in the system may result in unfeasible cases due to the high cost of computation and communication, decentralized methods distribute the computation among the robots in the group, enhancing the performance and making the system more efficient. Achieving a reliable …

Probabilistic Space Weather Modeling And Forecasting For The Challenge Of Orbital Drag In Space Traffic Management, Richard J. Licata Iii

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the modern space age, private companies are crowding the already-congested low Earth orbit (LEO) regime with small satellite mega constellations. With over 25,000 objects larger than 10 cm already in LEO, this rapid expansion is forcing us towards the enterprise on Space Traffic Management (STM). STM is an operational effort that focuses on conjunction assessment and collision avoidance between objects. While the equations of motion for objects in orbit are well-known, there are many uncertain parameters that result in the uncertainty of an object's future position. The force that the atmosphere exerts on satellite - known as drag - …

First Responders’ Assumptions: An Exploration Of Emergency Medical Technicians’ Secondary Traumatic Stress And Perceptions Of Substance Users, Glenn Noble

Graduate Theses, Dissertations, and Problem Reports (ETD)

Emergency medical technicians (EMT) and firefighters respond to critical incidents and provide emergent care. As the opioid crisis continues and drug overdose rates increase, first responders administer first aid to substance users, including Naloxone, more frequently. This study examined the influence of repeated exposure to drug-related critical incidents and provision of care to substance users on EMTs' and firefighters' secondary traumatic stress (STS) level, world assumptions, and substance use stigma. First responders' world assumptions, STS, burnout, and exposure to drug-related overdoses were analyzed for their power in predicting substance use stigma. Results suggest that occupational burnout, rather than STS, is …