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Articles 1801 - 1830 of 8514
Full-Text Articles in Entire DC Network
Reduced Cell Division Control Protein 42 Activity Compromises Hematopoiesis-Supportive Function Of Fanconi Anemia Mesenchymal Stromal Cells, Jian Xu, Xue Li, Allison Cole, Zachary Sherman, Wei Du
Reduced Cell Division Control Protein 42 Activity Compromises Hematopoiesis-Supportive Function Of Fanconi Anemia Mesenchymal Stromal Cells, Jian Xu, Xue Li, Allison Cole, Zachary Sherman, Wei Du
Clinical and Translational Science Institute
Hematopoietic stem cells (HSCs) preserve their ability to self-renew and differentiate to different lineages in the bone marrow (BM) niche, which is composed in large part by BM stromal cells. Studies have shown that altered signaling in the BM niche results in leukemia initiation or progression. Fanconi anemia (FA) is an inherited BM failure syndrome associated with extremely high risk of leukemic transformation. By employing two FA mouse models, here we have investigated the hematopoiesis-supportive function of FA BM mesenchymal stroma cells (MSCs). We found that MSCs deficient for Fanca or Fancc gene are defective in proliferation and prone to …
Early Stable Sinus Rhythm Associated With Greater Success 5 Years After Surgical Ablation, Niv Ad, Sari D. Holmes
Early Stable Sinus Rhythm Associated With Greater Success 5 Years After Surgical Ablation, Niv Ad, Sari D. Holmes
Clinical and Translational Science Institute
Background—An important challenge in surgical ablation for atrial fibrillation (AF) is the scarcity of publications on credible predictors of long-term success in procedures performed with ablation tools that produce consistently reliable transmural lesions. We examined factors associated with 1-year success and no atrial arrhythmia (AA) recurrence during 1 to 5 years after surgical ablation for AF. Methods—The study prospectively monitored 743 surgical ablation patients with complete rhythm follow-up at 12 months after the operation. No detected AA was defined as no known recurrence of AA, no cardioversions, and no catheter ablations at all available follow-up assessments. Results—Patients were a mean …
A Dedicated Breast-Pet/Ct Scanner: Evaluation Of Basic Performance Characteristics, Raymond R. Raylman, Will Van Kampen, Alexander V. Stolin, Wenbo Gong, Gangadhar Jaliparthi, Peter F. Martone, Mark F. Smith, David Sarment, Neal H. Clinthorne, Mark Perna
A Dedicated Breast-Pet/Ct Scanner: Evaluation Of Basic Performance Characteristics, Raymond R. Raylman, Will Van Kampen, Alexander V. Stolin, Wenbo Gong, Gangadhar Jaliparthi, Peter F. Martone, Mark F. Smith, David Sarment, Neal H. Clinthorne, Mark Perna
Clinical and Translational Science Institute
Purpose—Application of advanced imaging techniques, such as PET and x-ray CT, can potentially improve detection of breast cancer. Unfortunately, both modalities have challenges in the detection of some lesions. The combination of the two techniques, however, could potentially lead to an overall improvement in diagnostic breast imaging. The purpose of this investigation is to test the basic performance of a new dedicated breast-PET/CT. Methods—The PET component consists of a rotating pair of detectors. Its performance was evaluated using the NEMA NU4-2008 protocols. The CT component utilizes a pulsed x-ray source and flat panel detector mounted on the same gantry as …
Black Lung In The 21st Century: Disease, Law, And Policy, Evan Barrett Smith
Black Lung In The 21st Century: Disease, Law, And Policy, Evan Barrett Smith
West Virginia Law Review
No abstract provided.
Another Day Older And Deeper In Debt: Mitigating The Deleterious Effect Of Wage Garnishments On Appalachia's Low-Wage Workers, Faith Mullen
Another Day Older And Deeper In Debt: Mitigating The Deleterious Effect Of Wage Garnishments On Appalachia's Low-Wage Workers, Faith Mullen
West Virginia Law Review
No abstract provided.
Algebra, Wvu Mathematics Department
Algebra, Wvu Mathematics Department
M.S. Advanced and Ph.D. Entrance Exams
No abstract provided.
Swiss Settlement In Randolph County, West Virginia: A Study Of Land Deals, Policies, And Immigration, Elizabeth Satterfield
Swiss Settlement In Randolph County, West Virginia: A Study Of Land Deals, Policies, And Immigration, Elizabeth Satterfield
Munn Scholars Awards
No abstract provided.
Receivership: Another Option For Partition Of Heirs Property, Jesse J. Richardson Jr.
Receivership: Another Option For Partition Of Heirs Property, Jesse J. Richardson Jr.
West Virginia Law Review
No abstract provided.
Working For Recovery: How The Americans With Disabilities Act And State Human Rights Laws Can Facilitiate Successful Rehabilitation For Alcoholics And Drug Addicts, Samuel Brown Petsonk, Anne Marie Lofaso
Working For Recovery: How The Americans With Disabilities Act And State Human Rights Laws Can Facilitiate Successful Rehabilitation For Alcoholics And Drug Addicts, Samuel Brown Petsonk, Anne Marie Lofaso
West Virginia Law Review
No abstract provided.
Unified In Dignified Appalachian Pride, Aaron Ferrari, Will Rhee
Unified In Dignified Appalachian Pride, Aaron Ferrari, Will Rhee
West Virginia Law Review
No abstract provided.
Feature- Based And String-Based Models For Predicting Rna-Protein Interaction, Donald Adjeroh, Maen Allaga, Jun Tan, Jie Lin, Yue Jiang, Ahmed Abbasi, Xiaobo Zhou
Feature- Based And String-Based Models For Predicting Rna-Protein Interaction, Donald Adjeroh, Maen Allaga, Jun Tan, Jie Lin, Yue Jiang, Ahmed Abbasi, Xiaobo Zhou
Clinical and Translational Science Institute
In this work, we study two approaches for the problem of RNA-Protein Interaction (RPI). In the first approach, we use a feature-based technique by combining extracted features from both sequences and secondary structures. The feature-based approach enhanced the prediction accuracy as it included much more available information about the RNA-protein pairs. In the second approach, we apply search algorithms and data structures to extract effective string patterns for prediction of RPI, using both sequence information (protein and RNA sequences), and structure information (protein and RNA secondary structures). This led to different string-based models for predicting interacting RNA-protein pairs. We show …
Hydrophilic Polymer Embolism: Implications For Manufacturing, Regulation, And Postmarket Surveillance Of Coated Intravascular Medical Devices, Rashi I. Mehta, Rupal I. Mehta
Hydrophilic Polymer Embolism: Implications For Manufacturing, Regulation, And Postmarket Surveillance Of Coated Intravascular Medical Devices, Rashi I. Mehta, Rupal I. Mehta
Clinical and Translational Science Institute
Hydrophilic polymers are ubiquitously applied as surface coatings on catheters and intravascular medical technologies. Recent clinical literature has heightened awareness on the complication of hydrophilic polymer embolism (HPE), the phenomenon wherein polymer coating layers separate from catheter and device surfaces, and may be affiliated with a range of unanticipated adverse reactions. Significant system barriers have limited and delayed reporting on this iatrogenic complication, the full effects of which remain under-recognized by healthcare providers and manufacturers of various branded devices. In 2015, the United States Food and Drug Administration acknowledged rising clinical concerns and stated that the agency would work with …
Nudt19 Is A Renal Coa Diphosphohydrolase With Biochemical And Regulatory Properties That Are Distinct From The Hepatic Nudt7 Isoform, Stephanie A. Shumar, Evan W. Kerr, Werner J. Geldenhuys, Grace E. Montgomery, Paolo Fagone, Puchong Thirawatananond, Harry Saavedra, Sandra B. Gabelli, Roberta Leonardi
Nudt19 Is A Renal Coa Diphosphohydrolase With Biochemical And Regulatory Properties That Are Distinct From The Hepatic Nudt7 Isoform, Stephanie A. Shumar, Evan W. Kerr, Werner J. Geldenhuys, Grace E. Montgomery, Paolo Fagone, Puchong Thirawatananond, Harry Saavedra, Sandra B. Gabelli, Roberta Leonardi
Clinical and Translational Science Institute
CoA is the major acyl carrier in mammals and a key cofactor in energy metabolism. Dynamic regulation of CoA in different tissues and organs supports metabolic flexibility. Two mammalian Nudix hydrolases, Nudt19 and Nudt7, degrade CoA in vitro. Nudt19 and Nudt7 possess conserved Nudix and CoA signature sequences and specifically hydrolyze the diphosphate bond of free CoA and acyl-CoAs to form 3′,5′-ADP and 4′-(acyl)phosphopantetheine. Limited information is available on these enzymes, but the relatively high abundance of Nudt19 and Nudt7 mRNA in the kidney and liver, respectively, suggests that they play specific roles in the regulation of CoA levels in …
Validation Of A Dietary Screening Tool In A Middle-Aged Appalachian Population, Melissa Ventura Marra, Sowmyanarayanan V. Thuppal, Elizabeth J. Johnson, Regan L. Bailey
Validation Of A Dietary Screening Tool In A Middle-Aged Appalachian Population, Melissa Ventura Marra, Sowmyanarayanan V. Thuppal, Elizabeth J. Johnson, Regan L. Bailey
Clinical and Translational Science Institute
Proactive nutrition screening is an effective public health strategy for identifying and targeting individuals who could benefit from making dietary improvements for primary and secondary prevention of disease. The Dietary Screening Tool (DST) was developed and validated to assess nutritional risk among rural older adults. The purpose of this study was to evaluate the utility and validity of the DST to identify nutritional risk in middle-aged adults. This cross-sectional study in middle-aged adults (45–64 year olds, n = 87) who reside in Appalachia, examined nutritional status using an online health survey, biochemical measures, anthropometry, and three representative 24-h dietary recalls. …
Exploring The Genomic Basis Of Early Childhood Caries: A Pilot Study, Jami L. Ballantine, Jenna C. Carlson, Andrea G. Ferreira Zandoná, Cary Agler, Leslie P. Zeldin, Richard Gary Rozier, Michael W. Roberts, Patricia V. Basta, Jason Luo, Mikafui E. Antonio-Obese, Daniel W. Mcneil, Robert J. Weyant, Richard J. Crout, Rebecca L. Slayton, Steven M. Levy, John R. Shaffer, Mary L. Marazita, Kari E. North, Kimon Divaris
Exploring The Genomic Basis Of Early Childhood Caries: A Pilot Study, Jami L. Ballantine, Jenna C. Carlson, Andrea G. Ferreira Zandoná, Cary Agler, Leslie P. Zeldin, Richard Gary Rozier, Michael W. Roberts, Patricia V. Basta, Jason Luo, Mikafui E. Antonio-Obese, Daniel W. Mcneil, Robert J. Weyant, Richard J. Crout, Rebecca L. Slayton, Steven M. Levy, John R. Shaffer, Mary L. Marazita, Kari E. North, Kimon Divaris
Clinical and Translational Science Institute
Objective. A genetic component in early childhood caries (ECC) is theorized, but no genomewide investigations of ECC have been conducted. This pilot study is part of a long-term research program aimed to: (1) determine the proportion of ECC variance attributable to the human genome and (2) identify ECC-associated genetic loci. Methods. The study’s community-based sample comprised 212 children (mean age=39 months; range = 30–52 months; males = 55%; Hispanic/ Latino = 35%, African-American = 32%; American Academy of Pediatric Dentistry definition of ECC prevalence = 38%). Approximately 2.4 million single nucleotide polymorphisms (SNPs) were genotyped using DNA purified from saliva. …
A Two-Tiered Strategy For Preventing Complications Of Bereavement In The First Thirteen Months Post-Loss: A Pilot Study Using Peer Supports With Professional Therapist Back-Up, Mark D. Miller, Jacqueline Stack, Charles F. Reynolds Iii
A Two-Tiered Strategy For Preventing Complications Of Bereavement In The First Thirteen Months Post-Loss: A Pilot Study Using Peer Supports With Professional Therapist Back-Up, Mark D. Miller, Jacqueline Stack, Charles F. Reynolds Iii
Clinical and Translational Science Institute
This feasibility and acceptance pilot study for preventing complications of bereavement within the first year post loss recruited 20 adult grievers within 9 months of becoming bereft and assigned consenting subjects to peer supporters trained by a non-profit bereavement support organization for weekly or bi-weekly telephone-based peer support until month 13 post-loss. Subjects who met DSM-5 criteria for major depressive disorder or showed an Inventory of Complicated Grief (ICG) score exceeding 19, 6 months or more post loss, were assigned to 12 to 16 weeks of interpersonal psychotherapy (IPT) with an experienced therapist. Eight and six subjects completed the protocol …
Long-Term Outcome Following Concomitant Mitral Valve Surgery And Cox Maze Procedure For Atrial Fibrillation, Niv Ad, Sari D. Holmes, Paul S. Massimiano, Anthony J. Rongione, Lisa M. Fornaresio
Long-Term Outcome Following Concomitant Mitral Valve Surgery And Cox Maze Procedure For Atrial Fibrillation, Niv Ad, Sari D. Holmes, Paul S. Massimiano, Anthony J. Rongione, Lisa M. Fornaresio
Clinical and Translational Science Institute
Objective—Atrial fibrillation (AF) is associated with increased early and long-term morbidity/ mortality following valve surgery. This study examined long-term influence of concomitant full Cox maze (CM) and mitral valve procedures on freedom from atrial arrhythmia and stroke. Methods—This sample comprised patients who underwent CM with a mitral valve procedure (N = 473). Data on rhythm, medication status, and clinical events captured according to Heart Rhythm Society guidelines at 6, 9, 12, 18, and 24 months and yearly thereafter up to 7 years. Results—Mean age was 65 years, mean left atrium size was 5.3 cm, and 15% had paroxysmal AF. Perioperative …
The History Of Proximal Carotid Protection And Flow Reversal To Prevent Stent Angioplasty Embolization, Juan Parodi, Mark C. Bates, Takao Ohki, Claudio Schönholz
The History Of Proximal Carotid Protection And Flow Reversal To Prevent Stent Angioplasty Embolization, Juan Parodi, Mark C. Bates, Takao Ohki, Claudio Schönholz
Clinical and Translational Science Institute
Innovation in medicine is often driven by the observations of imaginative physicians who are blessed with insatiable curiosity, coupled with the inability to accept technical boundaries, the status quo of patient care, or the acceptance of procedural morbidity. Few examples illustrate this truism better than the physician-originated clinical research that transformed the safety of carotid stent angioplasty over the last 2 decades. Initial clinical application of carotid stenting suggested that proximal protection may be a better approach to prevent embolic stroke during the angioplasty procedure. The history of how this innovation was developed is particularly relevant as vascular surgeons adopt …
Interpreting Economic Diversity As The Presence Of Multiple Specializations, Jing Chen
Interpreting Economic Diversity As The Presence Of Multiple Specializations, Jing Chen
Regional Research Institute Working Papers
Conventional wisdom indicates that economic specialization can promote economic growth, whereas economic stability is theoretically associated with diversified economies. This conflicting relationship between specialization and diversity has been questioned, as regional scientists have suggested that specialization and diversity can coexist in a regional economy and proposed the concept of diversified specializations. To test this proposition empirically, three Herfindahl Hirschman Indices measuring regional economic diversity were used to examine the relationship between economic structure and regional economic performance among 359 metropolitan statistical areas (MSA) in the contiguous U.S. The first index measures economic diversity across 87 three-digit North American Industry Classification …
Community-Deliverable Exercise And Depression In Adults With Arthritis: Confirmatory Evidence Of A Meta-Analysis Using The Ivhet Model, George A. Kelley, Kristi S. Kelley
Community-Deliverable Exercise And Depression In Adults With Arthritis: Confirmatory Evidence Of A Meta-Analysis Using The Ivhet Model, George A. Kelley, Kristi S. Kelley
Clinical and Translational Science Institute
Objective—Using the traditional random-effects model, a recently reported standardized effect size (g) reduction of −0.42 (95% CI, −0.58 to −0.27) was observed as a result of communitydeliverable exercise in adults with arthritis and other rheumatic diseases (AORD). However, a recently proposed alternative model (IVhet) has been shown to have superior coverage probability to the random-effects model. The purpose of this brief report was to compare these previous random-effects results with the IVhet model. Methods—Based on a previous meta-analysis of 35 g’s representing 2,449 participants, results were pooled using the IVhet model. Influence analysis, number needed-to-treat (NNT), percentile improvement, and gross …
The Use Of Teledermoscopy In The Accurate Identification Of Cancerous Skin Lesions In The Adult Population: A Systematic Review, Amy F. Bruce, Jennifer A. Mallow, Laurie A. Theeke
The Use Of Teledermoscopy In The Accurate Identification Of Cancerous Skin Lesions In The Adult Population: A Systematic Review, Amy F. Bruce, Jennifer A. Mallow, Laurie A. Theeke
Clinical and Translational Science Institute
Background: The use of teledermoscopy in the diagnostic management of pre-cancerous and cancerous skin lesions involves digital dermoscopic images transmitted over telecommunication networks via email or web applications. Teledermoscopy may improve the accuracy in clinical diagnoses of melanoma skin cancer if integrated into electronic medical records and made available to rural communities, potentially leading to decreased morbidity and mortality. Objective and method: The purpose of this paper is to present a systematic review of evidence on the use of teledermoscopy to improve the accuracy of skin lesion identification in adult populations. The PRISMA method guided the development of this systematic …
Absolute Lymphocyte And Neutrophil Counts In Neonatal Ischemic Brain Injury, J M. Povroznik, E B. Engler-Chiurazzi, T Nanavati, P Pergami
Absolute Lymphocyte And Neutrophil Counts In Neonatal Ischemic Brain Injury, J M. Povroznik, E B. Engler-Chiurazzi, T Nanavati, P Pergami
Clinical and Translational Science Institute
Objectives: This study aimed to identify differences in absolute neutrophils, lymphocytes, and neutrophil-to-lymphocyte ratio between neonates with two forms of ischemic brain injury, hypoxic-ischemic encephalopathy, and acute ischemic stroke, compared to controls. We also aimed to determine whether this neutrophil/lymphocyte response pattern is associated with disease severity or is a consequence of the effects of total-body cooling, an approved treatment for moderate-to-severe hypoxic-ischemic encephalopathy. Methods: A retrospective chart review of 101 neonates with hypoxic-ischemic encephalopathy+total-body cooling (n=26), hypoxic-ischemic encephalopathy (n=12), acute ischemic stroke (n=15), and transient tachypnea of the newborn (n=48) was conducted; transient tachypnea of the newborn neonates were …
Crosstalk Among Lncrnas, Micrornas And Mrnas In The Muscle ‘Degradome’ Of Rainbow Trout, Bam Paneru, Ali Ali, Rafet Al-Tobasei, Brett Kenney, Mohamed Salem
Crosstalk Among Lncrnas, Micrornas And Mrnas In The Muscle ‘Degradome’ Of Rainbow Trout, Bam Paneru, Ali Ali, Rafet Al-Tobasei, Brett Kenney, Mohamed Salem
Faculty & Staff Scholarship
In fish, protein-coding and noncoding genes involved in muscle atrophy are not fully characterized. In this study, we characterized coding and noncoding genes involved in gonadogenesis-associated muscle atrophy, and investigated the potential functional interplay between these genes. Using RNA- Seq, we compared expression pattern of mRNAs, long noncoding RNAs (lncRNAs) and microRNAs of atrophying skeletal muscle from gravid females and control skeletal muscle from age-matched sterile individuals. A total of 852 mRNAs, 1,160 lncRNAs and 28 microRNAs were differentially expressed (DE) between the two groups. Muscle atrophy appears to be mediated by many genes encoding ubiquitin- proteasome system, autophagy related …
Bordetella Pertussis Whole Cell Immunization, Unlike Acellular Immunization, Mimics Naïve Infection By Driving Hematopoietic Stem And Progenitor Cell Expansion In Mice, Melinda E. Varney, Dylan T. Boehm, Katherine Deroos, Evan S. Nowak, Ting Y. Wong, Emel Sen-Kilic, Shebly D. Bradford, Cody Elkins, Matthew S. Epperly, William T. Witt, Mariette Barbier, F. Heath Damron
Bordetella Pertussis Whole Cell Immunization, Unlike Acellular Immunization, Mimics Naïve Infection By Driving Hematopoietic Stem And Progenitor Cell Expansion In Mice, Melinda E. Varney, Dylan T. Boehm, Katherine Deroos, Evan S. Nowak, Ting Y. Wong, Emel Sen-Kilic, Shebly D. Bradford, Cody Elkins, Matthew S. Epperly, William T. Witt, Mariette Barbier, F. Heath Damron
Faculty & Staff Scholarship
Hematopoietic stem and progenitor cell (HSPC) compartments are altered to direct immune responses to infection. Their roles during immunization are not well-described. To elucidate mechanisms for waning immunity following immunization with acellular vaccines (ACVs) against Bordetella pertussis (Bp), we tested the hypothesis that immunization with Bp ACVs and whole cell vaccines (WCVs) differ in directing the HSPC characteristics and immune cell development patterns that ultimately contribute to the types and quantities of cells produced to fight infection. Our data demonstrate that compared to control and ACV-immunized CD-1 mice, immunization with an efficacious WCV drives expansion of hematopoietic multipotent progenitor cells …
The Endogenous Cannabinoid System: A Budding Source Of Targets For Treating Inflammatory And Neuropathic Pain, Giulia Donvito, Sara R. Nass, Jenny L. Wilkerson, Zachary A. Curry, Lesley D. Schurman, Steven G. Kinsey, Aron H. Lichtman
The Endogenous Cannabinoid System: A Budding Source Of Targets For Treating Inflammatory And Neuropathic Pain, Giulia Donvito, Sara R. Nass, Jenny L. Wilkerson, Zachary A. Curry, Lesley D. Schurman, Steven G. Kinsey, Aron H. Lichtman
Clinical and Translational Science Institute
A great need exists for the development of new medications to treat pain resulting from various disease states and types of injury. Given that the endogenous cannabinoid (that is, endocannabinoid) system modulates neuronal and immune cell function, both of which play key roles in pain, therapeutics targeting this system hold promise as novel analgesics. Potential therapeutic targets include the cannabinoid receptors, type 1 and 2, as well as biosynthetic and catabolic enzymes of the endocannabinoids N-arachidonoylethanolamine and 2-arachidonoylglycerol. Notably, cannabinoid receptor agonists as well as inhibitors of endocannabinoid-regulating enzymes fatty acid amide hydrolase and monoacylglycerol lipase produce reliable antinociceptive effects, …
Difficulty Concentrating In Generalized Anxiety Disorder: An Evaluation Of Incremental Utility And Relationship To Worry, Lauren S. Hallion, Shari A. Steinman, Susan N. Kusmierski
Difficulty Concentrating In Generalized Anxiety Disorder: An Evaluation Of Incremental Utility And Relationship To Worry, Lauren S. Hallion, Shari A. Steinman, Susan N. Kusmierski
Clinical and Translational Science Institute
Difficulty concentrating is one of the most common diagnostic criteria across DSM-5 categories, especially within the emotional (mood- and anxiety-related) disorders. A substantial literature has characterized cognitive functioning in emotional disorders using objective (behavioral) computerized cognitive tasks. However, diagnoses are typically formed on the basis of subjective (self-reported; clinician-rated) assessments of symptoms, and little is known about difficulty concentrating as a symptom. These questions are particularly important for generalized anxiety disorder (GAD), which has long been the subject of nosological debates, and for which several theoretical models that suggest a central role for cognitive impairments (including difficulty concentrating) in the …
Mind The Hype: A Critical Evaluation And Prescriptive Agenda For Research On Mindfulness And Meditation, Nicholas T. Van Dam, Marieke K. Van Vugt, David R. Vago, Laura Schmalzl, Clifford D. Saron, Andrew Olendzki, Ted Meissner, Sara W. Lazar, Catherine E. Kerr, Jolie Gorchov, Kieran C. R. Fox, Brent A. Field, Willoughby B. Britton, Julie A. Brefczynski-Lewis, David E. Meyer
Mind The Hype: A Critical Evaluation And Prescriptive Agenda For Research On Mindfulness And Meditation, Nicholas T. Van Dam, Marieke K. Van Vugt, David R. Vago, Laura Schmalzl, Clifford D. Saron, Andrew Olendzki, Ted Meissner, Sara W. Lazar, Catherine E. Kerr, Jolie Gorchov, Kieran C. R. Fox, Brent A. Field, Willoughby B. Britton, Julie A. Brefczynski-Lewis, David E. Meyer
Clinical and Translational Science Institute
During the past two decades, mindfulness meditation has gone from being a fringe topic of scientific investigation to being an occasional replacement for psychotherapy, tool of corporate well-being, widely implemented educational practice, and “key to building more resilient soldiers”. Yet the mindfulness movement and empirical evidence supporting it have not gone without criticism. Misinformation and poor methodology associated with past studies of mindfulness may lead public consumers to be harmed, misled, and disappointed. Addressing such concerns, the present article discusses the difficulties of defining mindfulness, delineates the proper scope of research into mindfulness practices, and explicates crucial methodological issues for …
Development Of An Instrument To Measure Faculty's Information And Communication Technology Access (Ficta), Kamal Ahmed Soomro, Ugur Kale, Reagan Curtis, Mete Akcaoglu, Malayna Bernstein
Development Of An Instrument To Measure Faculty's Information And Communication Technology Access (Ficta), Kamal Ahmed Soomro, Ugur Kale, Reagan Curtis, Mete Akcaoglu, Malayna Bernstein
Clinical and Translational Science Institute
The phenomenon of “digital divide” is complex and multidimensional, extending beyond issues of physical access. The purpose of this study was to develop a scale to measure a range of factors related to digital divide among higher education faculty and to evaluate its reliability and validity. Faculty’s Information and Communication Technology Access (FICTA) scale was tested and validated with 322 faculty teaching in public and private sector universities. Principal components analysis with varimax rotation confirmed an 8-factor solution corresponding to various dimensions of ICT access. The 57-item FICTA scale demonstrated good psychometric properties and offers researchers a tool to examine …
Illness Representations Of Pertussis And Predictors Of Child Vaccination Among Mothers In A Strict Vaccination Exemption State, Rahul Garg, Abdulkarim Meraya, Pamela J. Murray, Kimberly Kelly
Illness Representations Of Pertussis And Predictors Of Child Vaccination Among Mothers In A Strict Vaccination Exemption State, Rahul Garg, Abdulkarim Meraya, Pamela J. Murray, Kimberly Kelly
Clinical and Translational Science Institute
Background—Vaccine preventable diseases are making a comeback in the US. However, research is lacking on illness representations of vaccine preventable diseases and their application in improving childhood immunization. Objective—We utilized the common sense model of self-regulation to examine illness representations of pertussis and their associations with child’s receipt of any vaccine, up-to-date vaccination status, and mothers’ intentions to follow the recommended vaccination schedule in the future. Methods—We developed vaccine worry and vaccine hassles scales to assess mothers’ worries and hassles for child vaccination, and used an open ended question to assess mother’s illness representations of pertussis. We surveyed mothers with …
Reiterated Concerns And Further Challenges For Mindfulness And Meditation Research: A Reply To Davidson And Dahl, Nicholas T. Van Dam, Marieke K. Van Vugt, David R. Vago, Laura Schmalzl, Clifford D. Saron, Andrew Olendzki, Ted Meissner, Sara W. Lazar, Jolie Gorchov, Kieran C. R. Fox, Brent A. Field, Willoughby B. Britton, Julie A. Brefczynski-Lewis, David E. Meyer
Reiterated Concerns And Further Challenges For Mindfulness And Meditation Research: A Reply To Davidson And Dahl, Nicholas T. Van Dam, Marieke K. Van Vugt, David R. Vago, Laura Schmalzl, Clifford D. Saron, Andrew Olendzki, Ted Meissner, Sara W. Lazar, Jolie Gorchov, Kieran C. R. Fox, Brent A. Field, Willoughby B. Britton, Julie A. Brefczynski-Lewis, David E. Meyer
Clinical and Translational Science Institute
In response to our article, Davidson and Dahl offer commentary and advice regarding additional topics crucial to a comprehensive prescriptive agenda for future research on mindfulness and meditation. Their commentary raises further challenges and provides an important complement to our article. More consideration of these issues is especially welcome because limited space precluded us from addressing all relevant topics. While we agree with many of Davidson and Dahl’s suggestions, the present reply (a) highlights reasons why the concerns we expressed are still especially germane to mindfulness and meditation research (even though those concerns may not be entirely unique) and (b) …