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New Methodologies For In Vitro Analysis Of Binding And Functional Activity Of Sigma Receptor Ligands, James A. Fishback Jan 2011

New Methodologies For In Vitro Analysis Of Binding And Functional Activity Of Sigma Receptor Ligands, James A. Fishback

Graduate Theses, Dissertations, and Problem Reports (ETD)

Sigma receptors represent a promising drug development target for a number of therapeutic indications including cancer, depression, psychostimulant abuse and stroke. To date, two subtypes of sigma receptors have been identified; sigma1 and sigma2. Their respective roles in normal physiology and in disease processes are a subject of ongoing studies. Consequently, the discovery and development of subtype specific agonist and antagonist ligands remains a key research goal. To date, no in vitro functional assay suitable for routine screening of putative sigma ligands has been reported. As a result, radioligand binding assays are used as a primary screen. Therefore, to support …

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Bioscience Laboratory: Online And Face-To-Face Laboratory Experiences In Requisite Biosciences For Nursing At A Community College, Deborah K. Folger Jan 2011

Bioscience Laboratory: Online And Face-To-Face Laboratory Experiences In Requisite Biosciences For Nursing At A Community College, Deborah K. Folger

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to analyze student perceptions of the online and face-to-face bioscience laboratory experiences in Anatomy and Physiology and Microbiology. The study took place at a community college in a rural geographic area and data were collected from associate degree seeking first and second year nursing students via a survey questionnaire and student focus groups in addition to archival enrollment and graduate data. The research study was guided by the following questions: What are nursing student perceptions concerning the impact of Anatomy and Physiology and Microbiology bioscience laboratory experiences on the transfer of knowledge to nursing …

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Effects Of Acute And Repeated Administration Of Diazepam On Delay Discounting In Lewis And Fischer 344 Rats, Sally L. Huskinson Jan 2011

Effects Of Acute And Repeated Administration Of Diazepam On Delay Discounting In Lewis And Fischer 344 Rats, Sally L. Huskinson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Impulsive choice is often examined using a delay-discounting procedure where choice is between two reinforcers of different magnitudes presented at varying delays. Individual discounting rates can be influenced by many factors including strain differences and drug effects. Lewis (LEW) and Fischer 344 (F344) rats have behavioral and neurochemical differences relevant to delay discounting and were used to examine effects of acute and repeated diazepam administration on impulsive choice. Consistent with previous literature, larger-reinforcer choice decreased as a function of increasing delays for all rats, and steeper discounting functions occurred for LEW relative to F344 rats. Acute and repeated diazepam administration …

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Vegetative Compatibility In Arbuscular Mycorrhizal Fungi, Sonia Purin Jan 2011

Vegetative Compatibility In Arbuscular Mycorrhizal Fungi, Sonia Purin

Graduate Theses, Dissertations, and Problem Reports (ETD)

The process of anastomosis promotes interconnectivity between hyphal branches during formation of a mycelial network and between fungal colonies. Self anastomosis involves fusion within a mycelium from a germinating spore, and this process is common in all species of fungi. Non-self anastomosis involves fusion between hyphae from different spores or colonies and allows lateral gene transfer, but this process is much rarer. Anastomosis in Ascomycota is well studied, but little is known for asexual arbuscular mycorrhizal fungi (AMF) in Glomeromycota. Because AMF are obligate symbionts in plant roots, studies have focused on anastomosis in asymbiotic hyphae of germinating spores. To …

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Assessments Of Marketing And Management Practices Of Appalachian Hardwood Sawmills, David Bradley Summerfield Jan 2011

Assessments Of Marketing And Management Practices Of Appalachian Hardwood Sawmills, David Bradley Summerfield

Graduate Theses, Dissertations, and Problem Reports (ETD)

A mail survey was conducted in the fall of 2010 to investigate the profitability aspects of the Appalachian hardwood sawmills. Specifically, the survey focused on changes in production, employment, marketing, export and energy efficiency practices between 2008 and 2010. The majority of the respondents used circle-saw headrigs (57%) and the remaining (43%) used bandsaw headrigs. The results indicated that employees in the Appalachian region had decreased by 28.88 percent while production decreased by 26 percent. Among responding sawmills, the number of employees decreased significantly since the economic downturn (p=0.0267) although four survey respondents reported hiring new employees. The most employment …

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Phosphodiesterase-4 In The Brain: Effects Of Pharmacological Inhibition And Mutation Of Disc1, Lan Xiao Jan 2011

Phosphodiesterase-4 In The Brain: Effects Of Pharmacological Inhibition And Mutation Of Disc1, Lan Xiao

Graduate Theses, Dissertations, and Problem Reports (ETD)

The effects of treatment with PDE4 inhibitors on cAMP/pCREB signaling, hippocampal neurogenesis and immobility in forced-swim test and the effects of DISC1 mutation on cAMP/pCREB signaling, PDE4 subtypes and PDE4 activity and high-affinity rolipram binding state were determined. Acute treatment with PDE4 inhibitors increased cAMP and pCREB transiently, as determined by ELISA and Western blotting, respectively. Repeated treatment with PDE4 inhibitors for 16 days produced antidepressant-like effect as evidence by decreased immobility in forced-swim test, increased cAMP/pCREB signaling and enhanced hippocampal neurogenesis. PDE4 inhibitors which preferentially interact with the high-affinity rolipram binding state, such as rolipram and piclamilast, produced greater …

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Formulating A Conceptual Framework To Understand Native American Perceptions Of Place And Identity: A Temporal Examination Of The Spatio-Social Effects Of Uneven Development Through Accumulation By Dispossession, Denyse Wyskup Jan 2011

Formulating A Conceptual Framework To Understand Native American Perceptions Of Place And Identity: A Temporal Examination Of The Spatio-Social Effects Of Uneven Development Through Accumulation By Dispossession, Denyse Wyskup

Graduate Theses, Dissertations, and Problem Reports (ETD)

This research dialectically conceptualizes how capitalist uneven development and subsequent occurrences has shaped, and continues to shape, Native American perceptions of place and identity. Specifically, this research focuses on accumulation by dispossession, a key component of uneven development, and the spatio-historic effects this form of dispossession has had on Native American lifeworlds. This research focuses primarily upon federal legislation in the form of treaties, acts, and court rulings as the predominant component sustaining accumulation by dispossession and, in turn, perpetuating uneven development within Native American communities. In order to more holistically conceptualize the impacts of accumulation by dispossession three Native …

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Concurrent Uptake Of Lead, Zinc, Cadmium And Copper And Health Risk Assessments In A Smelter Contaminated Soil., Mimi Roy Jan 2011

Concurrent Uptake Of Lead, Zinc, Cadmium And Copper And Health Risk Assessments In A Smelter Contaminated Soil., Mimi Roy

Graduate Theses, Dissertations, and Problem Reports (ETD)

The study area for this research was a smelter contaminated site in Harrison County, West Virginia. Soils in this site had elevated levels of lead, zinc, cadmium and copper. A multi-step chemical extraction study showed that zinc and cadmium were the most plant available elements while for Pb more than 75% was associated with the residual phase. Standard addition experiments showed readsorption rates less than 25 % for Pb and Cd, and less than 50% for Zn and Cu. Some common garden and residential plants were grown initially to study metal uptake in tissues. Radish, carrot, and chicory showed the …

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Microrna Regulation Of Kruppel-Like Factor 4 In Breast Cancer., Chen-Chung Lin Jan 2011

Microrna Regulation Of Kruppel-Like Factor 4 In Breast Cancer., Chen-Chung Lin

Graduate Theses, Dissertations, and Problem Reports (ETD)

Kruppel-like factor 4 (KLF4) is a transcription factor regulating cell growth and differentiation. In normal tissues, Kruppel-like factor 4 (KLF4) is typically expressed in post-mitotic epithelial cells and functions in epithelial cell differentiation. However, in the premalignant dysplastic lesions and invasive cancers of specific human tumor types such as skin cancer and breast cancer, KLF4 mRNA and protein are upregulated in proliferating cells. When KLF4 misexpressed in the basal keratinocytes of mouse skin, KLF4 can rapidly induce neoplastic progression to squamous cell carcinoma-like lesions. Consistent with its preferential expression in post-mitotic cells in vivo, KLF4 is likewise induced upon growth-arrest …

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Work Adjustment Of Survivors Of Tbi: Subjective Reporting And Indicators Of Work Status., Laura Kay Artman Jan 2011

Work Adjustment Of Survivors Of Tbi: Subjective Reporting And Indicators Of Work Status., Laura Kay Artman

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study investigated the use of self-reported functional limitations to indicate employment status of traumatic brain injury (TBI) survivors after returning to work. This study used data from the Job Accommodation Network (JAN) to examine the utility of self-reported functional limitations in indicating the work status of survivors of TBI. The first research question concerned the most common functional limitation reported by survivors of TBI. The second question asked which functional limitations, if any, could correctly classify the work status of TBI survivors. Results of binary logistic regression suggested that the presence of medical symptoms and emotional dysregulation were reliably …

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Engaging The Virtual Landscape: Toward An Experiential Approach To Exploring Place Through A Spatial Experience Engine, Susan J. Bergeron Jan 2011

Engaging The Virtual Landscape: Toward An Experiential Approach To Exploring Place Through A Spatial Experience Engine, Susan J. Bergeron

Graduate Theses, Dissertations, and Problem Reports (ETD)

The utilization of Geographic Information Systems (GIS) and other geospatial technologies in historical inquiry and the humanities has led to a number of projects that are exploring digital representations of past landscapes and places as platforms for synthesizing and representing historical and geographic information. Recent advancements in geovisualization, immersive environments, and virtual reality offer the opportunity to generate digital representations of cultural and physical landscapes, and embed those virtual landscapes with information and knowledge from multiple GIS sources. The development of these technologies and their application to historical research has opened up new opportunities to synthesize historical records from disparate …

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Role Of "Caax" Protein Processing In The Retina, Jeffrey Rowan Christiansen Jan 2011

Role Of "Caax" Protein Processing In The Retina, Jeffrey Rowan Christiansen

Graduate Theses, Dissertations, and Problem Reports (ETD)

Prenylation is a posttranslational modification which adds a lipid, either a farnesyl or geranylgeranyl group, to the C-terminal cysteine of proteins ending in a "CAAX" motif. Two additional steps referred to as "CAAX" protein processing follow prenylation. First, the terminal three amino acids are cleaved by the endoprotease RAS converting enzyme1 (RCE1), then isoprenylcysteine methyltransferase (ICMT) adds a methyl group to the cysteine. While it is clear that the addition of the prenyl group is required for the association of proteins with membranes, the function of proteolysis and methylation is not obvious. Two lines of evidence suggest a critical role …

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Mechano-Enzymatic Pretreatment Of Lignocellulosic Biomass, Bibu Philip George Jan 2011

Mechano-Enzymatic Pretreatment Of Lignocellulosic Biomass, Bibu Philip George

Graduate Theses, Dissertations, and Problem Reports (ETD)

Recalcitrance of lignocellulosic cell wall is a major hurdle that needs to be disrupted for biochemical refinery to be successful. Pretreatment of lignocellulosic materials play a key role for the conversion of lignocellulosic feed stocks to fermentable sugars. At present, various pretreatment technologies mainly achieved by empirical methods are available for the production of sugars from lignocellulosic polysaccharides. These methods depend largely upon the "demolition" of the cell wall by strong chemicals or using high energy input. As a result, these processes release "smaller compounds" as by-products or end products which inhibits downstream fermentation of monomeric sugars.;This project is a …

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Influencing Kidney Health And Function In Young Female Rats Through Dietary Alterations, Joseph Christopher Gigliotti Jan 2011

Influencing Kidney Health And Function In Young Female Rats Through Dietary Alterations, Joseph Christopher Gigliotti

Graduate Theses, Dissertations, and Problem Reports (ETD)

The occurrence of kidney failure in the US has drastically increased over the past decade. The decline in health associated with chronic kidney disease can be prevented if detected early in disease progression. However, substantial damage has often occurred before detection of renal disease is possible. Therefore, disease prevention (as in all diseases) is the optimal treatment.;In regards to the kidneys, dietary habits can have a profound influence on the function and overall kidney health. This is particularly evident in female rats due to their susceptibility to diet induced renal disease. In female rats, the initiation of chronic kidney disease …

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Diet Induced Alterations And Distribution Of Indices Of Lysine Catabolism, Stephanie K. Gatrell Jan 2011

Diet Induced Alterations And Distribution Of Indices Of Lysine Catabolism, Stephanie K. Gatrell

Graduate Theses, Dissertations, and Problem Reports (ETD)

Lysine is thought to be oxidized primarily by lysine alpha-ketoglutarate reductase (LKR) and saccharopine dehydrogenase (SDH), which are restricted to the mitochondrial matrix. Lysine is presumably transported through the plasma membrane by isoforms(s) of a cationic amino acid transporter (CAT). Although the mechanism(s) of lysine transport through the inner mitochondrial membrane is not known, it is presumptively transported by one or both mitochondrial "ornithine transporters" (ORC-1/ORC-2). Tissue distribution of LKR and the mechanism(s) responsible for alterations in hepatic lysine catabolism in swine are unclear. Also, the roles of the alternative pathways of lysine degradation, the L-amino acid oxidase-dependent (LAAO), in …

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Feeding Behavior Of Podisus Maculiventris (Say) (Hemiptera: Pentatomidae): Implications For Mass Rearing And Biological Control, Sudan Gyawaly Jan 2011

Feeding Behavior Of Podisus Maculiventris (Say) (Hemiptera: Pentatomidae): Implications For Mass Rearing And Biological Control, Sudan Gyawaly

Graduate Theses, Dissertations, and Problem Reports (ETD)

Spined soldier bug, Podisus maculiventris (Say) (Hemiptera: Pentatomidae), is a generalist predator feeding on more than 70 different insect species. P. maculiventris is noted for its potential for augmentative release against coleopteran and lepidopteran larvae. Successful mass rearing and determination of potential prey of a biological control agent are crucial factors that need consideration for success of a biological control agent in augmentative biological control. Firstly, study was conducted to investigate feeding behavior of P. maculiventris using yellow mealworm, Tenebrio molitor (Coleoptera: Tenebrionidae). Using different life stages of T. molitor that P. maculiventris could potentially feed on in mass rearing …

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Understanding The Role Of Ascorbic Acid And Gdp-Mannose Pyrophosphorylase Affecting Ammonium Sensitivity, Genome Stability And Flowering Time In Arabidopsis Thaliana, Chase F. Kempinski Jan 2011

Understanding The Role Of Ascorbic Acid And Gdp-Mannose Pyrophosphorylase Affecting Ammonium Sensitivity, Genome Stability And Flowering Time In Arabidopsis Thaliana, Chase F. Kempinski

Graduate Theses, Dissertations, and Problem Reports (ETD)

L-ascorbic acid is an important antioxidant in both plants and animals. In plants, it is important for detoxifying reactive oxygen species that are produced during photosynthesis and cellular metabolism. It also contributes to several facets of plant growth as an enzyme cofactor, signaling molecule, and a precursor to several other metabolites. It has been implicated in the control of flowering time and senescence as well as several other growth processes largely through work with the ascorbic acid-deficient vtc mutants of Arabidopsis thaliana. Biochemical and genetic experiments have identified several pathways contributing to ascorbic acid biosynthesis, with the D-mannose/L-galactose pathway predominantly …

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The Effect Of Dietary Inclusion Of Conjugated Linoleic Acid In Finishing Hog Feed On Sensory Characteristics And Storage Quality Indicators Of Pork Loin, Kaitlin Hope Maditz Jan 2011

The Effect Of Dietary Inclusion Of Conjugated Linoleic Acid In Finishing Hog Feed On Sensory Characteristics And Storage Quality Indicators Of Pork Loin, Kaitlin Hope Maditz

Graduate Theses, Dissertations, and Problem Reports (ETD)

Marbling in meat occurs when fat is distributed throughout the skeletal muscle and is visually apparent by light streaks of fat that look like a marble pattern. It is associated with increased quality, tenderness, and likeability. Incorporating dietary conjugated linoleic acid (CLA) into finishing hog feed increases intramuscular fat and decrease backfat in harvested pigs; therefore, the purpose of this study was to determine if inclusion of CLA in pig feed would increase intramuscular marbling and consumer likeability without compromising storage stability. Twenty pigs were housed in ten pens (2 pigs per pen) and fed either 1% Soybean oil or …

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Contraceptive Effect Of A Vaccine Targeting Leukemia Inhibitory Factor That Is Vital For Implantation, Angela Rae Lemons Jan 2011

Contraceptive Effect Of A Vaccine Targeting Leukemia Inhibitory Factor That Is Vital For Implantation, Angela Rae Lemons

Graduate Theses, Dissertations, and Problem Reports (ETD)

Immunomodulation at the fetal-maternal interface is essential for the establishment and maintenance of pregnancy. Several interleukins have been shown to be key in this process. Leukemia inhibitory factor (LIF), a member of the interleukin-6 family of proteins, is vital for blastocyst implantation in both humans and mice. LIF is expressed by the uterine epithelium and stromal cells surrounding the blastocyst prior to implantation and acts via binding to the LIF receptor expressed on the endometrium. This study investigates the contraceptive effect of a vaccine prepared with peptides derived from LIF and LIF receptor in the murine model. The vaccine was …

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Drug-Drug Interactions: A Machine Learning Approach, William Wireko Mensah Jan 2011

Drug-Drug Interactions: A Machine Learning Approach, William Wireko Mensah

Graduate Theses, Dissertations, and Problem Reports (ETD)

Automatic detection of drug-drug interaction (DDI) is a difficult problem in pharmaco-surveillance. Recent practice for in vitro and in vivo pharmacokinetic drug-drug interaction studies have been based on carefully selected drug characteristics such as their pharmacological effects, and on drug-target networks, in order to identify and comprehend anomalies in a drug's biochemical function upon co-administration.;In this work, we present a novel DDI prediction framework that combines several drug-attribute similarity measures to construct a feature space from which we train three machine learning algorithms: Support Vector Machine (SVM), J48 Decision Tree and K-Nearest Neighbor (KNN) using a partially supervised classification algorithm …

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Ash Removal From Low Rank Coal, Deepankar Virendra Sharma Jan 2011

Ash Removal From Low Rank Coal, Deepankar Virendra Sharma

Graduate Theses, Dissertations, and Problem Reports (ETD)

The work presented here is concerned with cleaning of low rank coals such as Texas lignite. As a result, Jewett Texas lignite was cleaned from 28% ash by weight to 8.5%. In the first part of the thesis, it is proved that conventional cleaning techniques used for bituminous and sub-bituminous having pyritic impurities does not work for cleaning lignite coal because of different coal chemistry and the presence of clay impurities. Hence after trying conventional processes, there was a need for a new technique capable of removing clay from low rank coals.;Micronized coal, obtained from DevourX LLC, proved to be …

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Sensory Evaluation And Quality Indicators Of Nutritionally Enhanced Egg Product With Omega-3 Rich Oils, Helenia Dawn Sedoski Jan 2011

Sensory Evaluation And Quality Indicators Of Nutritionally Enhanced Egg Product With Omega-3 Rich Oils, Helenia Dawn Sedoski

Graduate Theses, Dissertations, and Problem Reports (ETD)

Heart disease is a leading cause of death in the United States. Omega-3 (n-3) fatty acids (FA) positively affect heart health while high levels of cholesterol are an indication of poor heart health. Nutritionally-enhanced low-cholesterol egg sticks fortified with n-3 FA were developed; quality indicators were measured and sensory evaluations were conducted. Store-bought eggs were separated and egg whites were mixed with oil, spray dried egg whites, annatto (color) and salt. The oil sources included: algae, menhaden, flaxseed, and canola oils. Experimental egg batters and mixed whole egg (control) were cooked in the shape of a cheese stick, vacuum packed, …

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Molecular Phylogeny Of The Oestroidea, Baneshwar Singh Jan 2011

Molecular Phylogeny Of The Oestroidea, Baneshwar Singh

Graduate Theses, Dissertations, and Problem Reports (ETD)

The superfamily Oestroidea includes approximately 9% (≈14,000 spp.) of the order Diptera. Many members of the superfamily are of medical, veterinary, agricultural, and forensic importance. Although Oestroidea has been the subject of much scientific scrutiny, the exact patterns of phylogenetic relationships among the key groups of the superfamily are unresolved and controversial. For a better understanding of oestroid evolutionary hypotheses, phylogenies of Oestroidea were reconstructed at several taxonomic levels using DNA sequence data. The specific aims were to determine the phylogeny of the 1) genus Chrysomya (Chrysomyinae); 2) subfamily Chrysomyinae (Calliphoridae); 3) family Oestridae (Oestroidea); and 4) family Calliphoridae (Oestroidea). …

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Emotional Pain And Acute Nociception, Alison M. Vargovich Jan 2011

Emotional Pain And Acute Nociception, Alison M. Vargovich

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examined differences and similarities in responses to acute nociception in adults with a significant history of emotional pain relative to matched controls with a significant past positive life experience and a sample of chronic pain patients. Using 28 volunteers who responded to advertisements (n = 14, emotional pain group; n = 14, positive life experience group), and 14 chronic pain patients from a prior study, this investigation utilized measures of pain threshold and tolerance during a laboratory finger pressure pain induction experiment. Each participant experienced two levels of pressure pain (i.e., high and low) and two levels of …

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Development Of An Emotional Pain Interview, Ben Weinstein Jan 2011

Development Of An Emotional Pain Interview, Ben Weinstein

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study developed and tested the Emotional Pain Interview (EPI), a semi-structured interview measuring emotional pain, using community dwelling adults with a significant history of emotional pain (n = 16; emotional pain group) relative to matched controls reporting a prior significant positive life experience (n = 16; positive life experience group). The EPI and a matching positive life event interview were used to assess all participants regarding prior emotionally painful and positive life experiences. Participants completed measures of anxiety sensitivity, depression, and posttraumatic stress disorder. Ratings of emotional responding (i.e., Valence, Arousal, and Control/Dominance) were made for prior emotionally painful …

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Dwindling Into A Wife: Women And The Culture Of Marriage In Britain, 1760-1820, Lori Halvorsen Zerne Jan 2011

Dwindling Into A Wife: Women And The Culture Of Marriage In Britain, 1760-1820, Lori Halvorsen Zerne

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation examines women and marriage ideology in courtship novels of the late eighteenth and early nineteenth centuries, specifically novels by Sarah Scott, Frances Burney, Maria Edgeworth, and Jane Austen. Instead of focusing on the heroines of these courtship novels, however, this project explores the marginalized female roles that orbit the courtship narrative: the chaperon, the mother-in-law, the governess, and the spinster. These four roles demonstrate the broad scope of female functions and services in the period while also calling into question the ideology that attempts to limit women only to the role of wife. The chaperon reveals the work …

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Rna In Forensic Science: Novel Techniques For Biological Evidence, Stephanie T. Young Jan 2011

Rna In Forensic Science: Novel Techniques For Biological Evidence, Stephanie T. Young

Graduate Theses, Dissertations, and Problem Reports (ETD)

The techniques currently utilized for collecting biological evidence at the scenes of violent crimes such as murder, rape, and kidnapping are employed simply to preserve evidence for future DNA analysis. Although DNA is extremely useful in forensic casework, biological samples possess yet another valuable molecule, RNA. The use of RNA in forensic analysis of samples is currently on the rise. In the past, RNA was thought to degrade much too quickly to be of any benefit to the forensic community. The work presented in this dissertation seeks to demonstrate otherwise. While true that RNA is not as stable as DNA, …

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Bam! Pow! Graphic Novels Fight Stereotypes In Academic Libraries: Supporting, Collecting, Promoting, Beth Jane Toren Dec 2010

Bam! Pow! Graphic Novels Fight Stereotypes In Academic Libraries: Supporting, Collecting, Promoting, Beth Jane Toren

University Libraries Faculty Scholarship

This study examines the launch of a graphic novel collection in an academic library and presents a study analyzing the increase of titles in Association of Research Libraries with the subject heading “Graphic Novels” between fall 2008 and fall 2009. Statistics show a 40% increase, averaging 62 additional titles, during a year of global financial crisis. Exploring the prejudice against comics lingering in more traditional corners of academia, this paper encourages librarians to counter stereotypes and therefore bring more people, including other librarians, to view graphic novels as literature. This study includes recommended practices for supporting, collecting, and promoting these …

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Laboratory And Real-World Measurement Of Diesel Particulate Matter, Yuebin Wu Dec 2010

Laboratory And Real-World Measurement Of Diesel Particulate Matter, Yuebin Wu

Graduate Theses, Dissertations, and Problem Reports (ETD)

West Virginia University's Center for Alternative Fuels, Engines, and Emissions (CAFEE) has designed and constructed, with support from the U.S. Department of Energy (DOE), the 'next level' transportable dual-primary full-flow dilution tunnel emissions-measurement laboratory. As one of the major contributors, the author participated in the design and the fabrication processes of this laboratory. A systematic SimulinkRTM model was built for the Particulate Matter (PM) sampling system and a parametric study of the PM system was performed. Modeling of gas chemical composition, mass and heat transfer, as well as modeling of the primary and the secondary tunnels, were conducted with this …

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Evaluating The Effects Of The Blennerhassett Island Bridge Crossing (Ohio River) On Soil, Vegetation, And Wildlife, Joshua Allen Vance Dec 2010

Evaluating The Effects Of The Blennerhassett Island Bridge Crossing (Ohio River) On Soil, Vegetation, And Wildlife, Joshua Allen Vance

Graduate Theses, Dissertations, and Problem Reports (ETD)

Corridor D was one of the original 23 highway corridors selected by the Appalachian Highway Development System in 1965 and stretches from Bridgeport, West Virginia to Cincinnati, Ohio. The last piece of Corridor D to be completed was the Blennerhassett Island Bridge which crosses over the Ohio River and Blennerhassett Island near Parkersburg, West Virginia and Belpre, Ohio. The Blennerhassett Island Bridge is a tied-arch style bridge about 1,220 m in length and 24 m above the ground and water surface. Construction of the bridge began in March 2005 and the bridge was opened to the public in June 2008. …

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