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WellBeing International

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Welfare-Aligned Sentience: Enhanced Capacities To Experience, Interact, Anticipate, Choose And Survive, David J. Mellor Jan 2019

Welfare-Aligned Sentience: Enhanced Capacities To Experience, Interact, Anticipate, Choose And Survive, David J. Mellor

General - Animal Welfare

The focus of this opinion is on the key features of sentience in animals which can experience different states of welfare encapsulated by the new term ‘welfare-aligned sentience’. This term is intended to exclude potential forms of sentience that do not enable animals in some taxa to have the subjective experiences which underlie different welfare states. As the scientific understanding of key features of sentience has increased markedly during the last 10 to 15 years, a major purpose here is to provide up-to-date information regarding those features. Eleven interconnected statements about sentience-associated body functions and behaviour are therefore presented and …

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Rspca Australia National Statistics 2018-2019, Rspca Australia Jan 2019

Rspca Australia National Statistics 2018-2019, Rspca Australia

General - Animal Welfare

The RSPCA receives thousands of animals every year in every state and territory in Australia. Annual statistics on the numbers of animals received, reclaimed or rehomed are compiled on a national basis by RSPCA Australia. The following statistics cover the 2018 to 2019 financial year and give details on the receipt and placement of animals by each state and territory RSPCA during that period. The statistics also include the number of cruelty complaints received by the RSPCA Inspectorate and prosecutions undertaken. Detailed information is provided in the following report.

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Religion As Animal And Alive, Paul Waldau Jan 2019

Religion As Animal And Alive, Paul Waldau

Religion

The notion of “living religion” is helpful in exploring how individuals and communities have across time and culture engaged their other-than-human neighbors in a local place as a response to the fact that each human individual clearly lives in a more-than-human world. Threads of observation and argument are woven together to suggest that focusing on nonhuman animals helps any human sustain the vibrant, living quality that so often has been a hallmark of a relevant and healthy religious/spiritual awareness.

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Good Practices For Animal Welfare In Agriculture Development, Janice Cox Jan 2019

Good Practices For Animal Welfare In Agriculture Development, Janice Cox

UN SDGs

The 2030 Agenda envisages a development model “in which humanity lives in harmony with nature and … other living species are protected[i].” While the relationship between animal welfare, environmental well-being and human development is starting to be discussed and evidenced, there remains very little recognition of this relationship and the crucial role animal welfare plays in sustainable development for people and planet in UN discussions of the Sustainable Development Goals (SDGs). This paper discusses this further, with specific reference to the development of good practice for animal welfare in agricultural development. However, it is recognized that there are also broader …

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The Land Of Meat And Potatoes? Exploring Ireland’S Vegan And Vegetarian Foodscape, Corey Lee Wrenn Jan 2019

The Land Of Meat And Potatoes? Exploring Ireland’S Vegan And Vegetarian Foodscape, Corey Lee Wrenn

Dietary Choice and Foods of Animal Origin Collection

While it would not be accurate to suggest that Ireland is a hub of veganism or vegetarianism, too often it is written off as inherently unsympathetic to the ethics of plant-based eating and anti-speciesist politics. While it is true that Irish culture is historically tied to speciesism and its economy is especially dependent upon “meat” and dairy production, Ireland’s relationship with other animals is complex and sometimes forgiving. This essay seeks to bring shape to the Irish vegan ethic, one that can be traced along its history of animism, agrarianism, ascendency, adaptation, and activism. From its pagan roots to its …

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Building A Vegan Feminist Network In The Professionalized Digital Age Of Third Wave Animal Activism, Corey Lee Wrenn Jan 2019

Building A Vegan Feminist Network In The Professionalized Digital Age Of Third Wave Animal Activism, Corey Lee Wrenn

Diversity and Social Movements Collection

Despite its legacy of feminist leadership and a continued female majority, the Nonhuman Animal rights movement has exhibited structural sexism across its various waves of protest. This institutionalized sexism not only inhibits women’s ability to protest safely and effectively, but also permeates the activist imagination and aggravates interpersonal violence. Even Nonhuman Animals as a feminized group are unwittingly disparaged in popular campaigns. This essay suggests that structural sexism in the Nonhuman Animal rights movement is nourished by its patriarchal organization, specifically its decision to professionalize. Twenty-first century vegan feminist activism on the margins has been able to circumvent the hegemony …

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Refinement On The Way Towards Replacement: Are We Doing What We Can?, Kathrin Herrmann Jan 2019

Refinement On The Way Towards Replacement: Are We Doing What We Can?, Kathrin Herrmann

Humane Science Movement Collection

No abstract provided.

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Retrospective Review Of Anesthetic And Analgesic Regimens Used In Animal Research Proposals, Kathrin Herrmann, Paul A. Flecknell Jan 2019

Retrospective Review Of Anesthetic And Analgesic Regimens Used In Animal Research Proposals, Kathrin Herrmann, Paul A. Flecknell

Experimental Research and Animal Welfare Collection

Pain has a profound effect on an animal’s wellbeing. In Germany, researchers using animals have been legally required to reduce any possible pain, suffering, distress or lasting harm to an absolute minimum since 1972. To evaluate how these provisions have been implemented in practice, an assessment of refinements to experimental techniques was conducted by retrospectively reviewing 684 surgical interventions described in 506 animal research applications that were sent to the German competent authorities for approval in 2010. This paper focuses on the efficacy of proposed anesthesia and peri- and postoperative analgesia. Postoperative analgesia was not proposed for 30% of surgeries. …

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Disease Prevention With A Plant-Based Lifestyle, Sabina V. Vyas Jan 2019

Disease Prevention With A Plant-Based Lifestyle, Sabina V. Vyas

Dietary Choice and Foods of Animal Origin Collection

Animal experiments are commonly conducted to understand human diseases and responses to treatment. As decades of research indicate, the use of nonhuman animals (hereinafter referred to as animals) to translate the side effects, benefits, and impact of medications and treatments on the human body has been demonstrated to be ineffective; while billions of animals and humans have suffered (Shanks, Greek and Greek, 2009). Due to misleading safety and efficacy data from animal experiments, humans are often prescribed medications that may not be as effective or as safe as the patient, or even physician, may have been led to believe (Akhtar, …

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Contesting Animal Experiments Through Ethics And Epistemology: In Defense Of A Political Critique Of Animal Experimentation, Arianna Ferrari Jan 2019

Contesting Animal Experiments Through Ethics And Epistemology: In Defense Of A Political Critique Of Animal Experimentation, Arianna Ferrari

Professional Science Research Ethics Collection

Generally, an animal experiment can be defined as an intervention on an animal, which causes suffering, harm, and distress, for scientific purposes. In this definition, animal experiments differ from more general scientific investigations concerning animals, such as observational studies in the wild in the fields of ethology or conservation, in which animals are involved but may not be harmed. Nowadays, the use of the term vivisection, in the case of animal experiments, is very controversial. This term originally referred to the cutting of living bodies for scientific purposes and has a long conceptual history (Maehle, 1992). In ancient times, it …

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How Can The Final Goal Of Completely Replacing Animal Procedures Successfully Be Achieved?, Christiane Baumgartl-Simons, Christiane Hohense Jan 2019

How Can The Final Goal Of Completely Replacing Animal Procedures Successfully Be Achieved?, Christiane Baumgartl-Simons, Christiane Hohense

Validation of Alternative Methods Collection

Article 23 of European Union (EU) Directive 86/609/EEC required that Member States promote the development and validation of alternative technologies and stated that the European Commission (EC) “shall report before the end of 1987 on the possibility of modifying tests and guidelines” (European Parliament, 1986, Article 23). This Directive was replaced by Directive 2010/63/EU on the protection of animals used for scientific purposes, which now requires that Member States develop and validate alternative approaches much more precisely and specifies that the ultimate objective is the “full replacement of procedures on live animals for scientific and educational purposes, as soon as …

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The Moral Status Of Animal Research Subjects In Industry: A Stakeholder Analysis, Sarah Kenehan Jan 2019

The Moral Status Of Animal Research Subjects In Industry: A Stakeholder Analysis, Sarah Kenehan

Morality and Ethics of Animal Experimentation Collection

The use of non-human animals (hereinafter referred to as animals) in research and testing is a widely accepted practice in many industries. Millions of animals each year are subjected to painful procedures that include everything from physical mutilation to drug addiction. According to the United States Department of Agriculture (usda), over 820,812 animals were experimented on in the United States in 2016 (usda, 2017), though this count does not include rats, mice, or birds, and dubiously relies solely on the self-reporting of laboratories (Humane Society of the United States, 2011; Keen, 2019, Chapter 10 in this Volume). Estimates suggest that …

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Political Campaigning: Where Scientific And Ethical Arguments Meet Public Policy, Emily Mcivor Jan 2019

Political Campaigning: Where Scientific And Ethical Arguments Meet Public Policy, Emily Mcivor

Animals and Public Policy Collection

The ambition of the paradigm shift we seek is vast, and the obstacles we face are intractable. For anyone opposing the use of non-human animals (hereinafter referred to as animals) in research and testing, the story has been the same from the start. Legitimate concern for animals has been all-too-easily dismissed as misguided sentimentality, and powerful vested interests have claimed scientific, economic, and moral superiority. But the ground is shifting. Animal researchers accept the need to provide scientific justification for their choices, and the protection of animals is increasingly recognized as a public good. Concern among citizens has been translated …

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How To Evaluate The Science Of Non-Human Animal Use In Biomedical Research And Testing: A Proposed Format For Debate, Ray Greek, Lisa A. Kramer Jan 2019

How To Evaluate The Science Of Non-Human Animal Use In Biomedical Research And Testing: A Proposed Format For Debate, Ray Greek, Lisa A. Kramer

Validation of Alternative Methods Collection

Over time, the interpretation of science has occasionally been corrupted by vested interest groups, be they financially motivated or ego driven. Scientific consensus and widespread public beliefs usually catch up with the evidence, but this can take a very long time and often costs lives. The use of non-human animals in biomedical research and testing is a scientific endeavor and, as such, can and should be evaluated in light of the best science currently available. But facts that have been accepted in all areas of science are routinely ignored or called into question by well-funded, vested interest groups, compromising the …

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Rethinking The 3rs: From Whitewashing To Rights, Charlotte E. Blattner Jan 2019

Rethinking The 3rs: From Whitewashing To Rights, Charlotte E. Blattner

Humane Science Movement Collection

Few other issues have prompted as many legislators to adopt legal instruction on the “proper” use of non-human animals (hereinafter referred to as animals) in medical and scientific research. Today, the 3Rs (replacement, reduction, and refinement of animals in scientific procedures) are globally accepted by a vast majority of states (Blattner, 2014); and prominent international organizations, such as the World Organisation for Animal Health (Terrestrial Animal Health Code, 2018, Article 7(8)(3)) and the Council of Europe (Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes, 1986, Articles 6(2), 7 and 8). Widespread acceptance of the …

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Beyond Plausibility Checks: A Case For Moral Doubt In Review Processes Of Animal Experimentation, Mara-Daria Cojocaru, Philipp Von Gall Jan 2019

Beyond Plausibility Checks: A Case For Moral Doubt In Review Processes Of Animal Experimentation, Mara-Daria Cojocaru, Philipp Von Gall

Morality and Ethics of Animal Experimentation Collection

The fact that countries all over the world continue to develop new regulations for experimentation on non-human animals testament that this practice raises many doubts. Our aim in this chapter is to show that one important type of doubt should receive more attention: a particular type of moral doubt that could play a pivotal role in the ethical review of animal experiments. We assume that there are a range of emotions that indicate morally complex or problematic situations. When one or all of these emotions are experienced, we say that someone is experiencing moral doubt. To illustrate this point, we …

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Human Wrongs In Animal Research: A Focus On Moral Injury And Reification, Jane Johnson, Anna Smajdor Jan 2019

Human Wrongs In Animal Research: A Focus On Moral Injury And Reification, Jane Johnson, Anna Smajdor

Morality and Ethics of Animal Experimentation Collection

Using arguments derived from the work of Axel Honneth (2006), we show that animal research involves an institutionalized failure to recognize nonhuman animals that not only reifies animals but the human persons engaged in this process, diminishing the scope of their moral agency and causing moral injury. In this chapter, we begin by briefly articulating the harms to animals in research and the more conventional harms to humans that can arise as a result of animal research, before making a case for the ethical damage wrought by the failures of recognition inherent within the system of animal research. We conclude …

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Increasing The Transparency Of Animal Experimentation: An Australian Perspective, Monika Merkes, Rob Buttrose Jan 2019

Increasing The Transparency Of Animal Experimentation: An Australian Perspective, Monika Merkes, Rob Buttrose

Animal Law and Legislation Collection

It has been argued that citizen stakeholders would be well served by greater transparency. The Transparency Register of the European Union (eu) (2016), for example, states that “Transparency is […] a key part of encouraging European citizens to participate more actively in the democratic life of the eu”. But why is transparency in non-human animal (hereinafter referred to as animal) research desirable, or indeed vital? Hadley (2012) argues that the public finance much animal research but do not know what impact their taxes and donations have on animals. Furthermore, he suggests that, since “people enjoy the benefits of animal research …

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Extrapolation Of Animal Research Data To Humans: An Analysis Of The Evidence, Rebecca Ram Jan 2019

Extrapolation Of Animal Research Data To Humans: An Analysis Of The Evidence, Rebecca Ram

Validation of Animal Experimentation Collection

The ethical arguments against animal experimentation remain ever-strong. In addition, the scientific case against the use of animals in research grows more compelling, with exponential progress in the development of alternative methods and new research technologies. The Dutch authorities recently announced an ambitious, but welcome, proposal to phase out “the use of laboratory animals in regulatory safety testing of chemicals, food ingredients, pesticides and (veterinary) medicines” by 2025, as well as “the use of laboratory animals for the release of biological products, such as vaccines” (Netherlands National Committee for the protection of animals used for scientific purposes, NCad, 2016, p. …

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Wasted Money In United States Biomedical And Agricultural Animal Research, Jim Keen Jan 2019

Wasted Money In United States Biomedical And Agricultural Animal Research, Jim Keen

Biomedicine and Animal Models in Research Collection

Biomedical and agricultural animal research uses millions of experimental animals and dozens of animal species each year by choice, precedent, or regulatory mandate in basic and applied life science research and toxicity testing of drugs, chemicals, and consumer products. Animal research is a large component of the international us$270 billion government-subsidized, biomedical industrial ecosystem (Chakma et al., 2014). In the United States (us) and presumably elsewhere, about half of these funds support animal research and testing (Institute of Medicine and National Research Council, 2012). Each year at least 115 million experimental animals (mostly mice and likely a significant underestimate) are …

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The Scientific Problems With Using Non-Human Animals To Predict Human Response To Drugs And Disease, Ray Greek, Lisa A. Kramer Jan 2019

The Scientific Problems With Using Non-Human Animals To Predict Human Response To Drugs And Disease, Ray Greek, Lisa A. Kramer

Pharmacology and Animal Models in Research Collection

Every year, and in countries around the world, significant time and resources are devoted to the noble cause of developing drugs to treat and cure human disease. With rare exception, drug interventions cannot reach commercialization without safety and efficacy having first been demonstrated in animal models. The intention of regulations, which require the use of animal models in such contexts, is to ensure that only safe and effective drugs end up being used by patients. Similarly, it is standard practice for researchers to employ animal models in their attempts to understand the way diseases present and progress in humans. Unfortunately, …

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Replacing Animal Tests To Improve Safety For Humans, Kathy Archibald, Robert Coleman, Tamara Drake Jan 2019

Replacing Animal Tests To Improve Safety For Humans, Kathy Archibald, Robert Coleman, Tamara Drake

Application of Alternative Methods Collection

In this chapter, we propose a new, pragmatic approach that could accelerate the replacement of most, if not all, regulatory animal tests with superior tests based on human biology. We also propose that changes to the requirements for safety testing, issued by the us Food and Drug Administration (fda), must be made in order to enable the use of superior new tests, which are currently disadvantaged by the outdated language of the regulations. But first, it is imperative to establish some level of understanding of the efficacy of existing animal-based methods in order to know whether any possible replacement is …

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Modernizing Biomedical Training: Replacing Live Animal Laboratories With Human Simulation, John Pawlowski, David Feinstein, Marie L. Crandall, Shalin Gala Jan 2019

Modernizing Biomedical Training: Replacing Live Animal Laboratories With Human Simulation, John Pawlowski, David Feinstein, Marie L. Crandall, Shalin Gala

Biomedicine and Animal Models in Research Collection

This chapter reviews the global trend towards a modernization of biomedical education in favor of simulation-based training methods, which studies confirm improve student learning and transference of applied skills to clinical practice, reduce laboratory costs, and spare animals from harmful procedures.

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Humane Education: The Tool For Scientific Revolution In Brazil, Vanessa Carli Bones, Rita De Cássia Maria Garcia, Gutemberg Gomes Alves, Rita Leal Paixão, Alexandro Aluísio Rocha, Karynn Capilé, Róber Bachinski Jan 2019

Humane Education: The Tool For Scientific Revolution In Brazil, Vanessa Carli Bones, Rita De Cássia Maria Garcia, Gutemberg Gomes Alves, Rita Leal Paixão, Alexandro Aluísio Rocha, Karynn Capilé, Róber Bachinski

Humane Education Movement Collection

Despite the predominance of traditional teacher-centered approaches, educators are constantly changing paradigms and social boundaries, by stimulating criticism with active learning based approaches, which are centered on contexts and experiences. Viewing students as individuals enables paradigm changes and inspires new perspectives on established theories and facts. This chapter discusses education in Brazil, with a focus on humane education. Humane education strives to foster compassion and respect for humans, nonhuman animals (hereinafter referred to as animals), and the environment by creating awareness of the needs of others and the effects of our actions. In this chapter we describe the process of …

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Animal Research For Alzheimer Disease: Failures Of Science And Ethics, John J. Pippin, Sarah E. Cavanaugh, Francesca Pistollato Jan 2019

Animal Research For Alzheimer Disease: Failures Of Science And Ethics, John J. Pippin, Sarah E. Cavanaugh, Francesca Pistollato

Biomedicine and Animal Models in Research Collection

This chapter addresses the epidemiology and current understanding of AD as a scientific and societal challenge, reviews the uses and results of animal research in basic science and drug development, and discusses risk factors and funding. Important follow-up topics, including current and in-development, human-relevant approaches for replacement of the failed animal research paradigm, deserve comparable treatment and hence are not addressed here. The reader is referred to the list of recommended readings at the end of the chapter for further discussion of these topics.

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The Changing Paradigm In Preclinical Toxicology: In Vitro And In Silico Methods In Liver Toxicity Evaluations, Fozia Noor Jan 2019

The Changing Paradigm In Preclinical Toxicology: In Vitro And In Silico Methods In Liver Toxicity Evaluations, Fozia Noor

Application of Alternative Methods Collection

In vitro methods, based on human primary cells, cell lines, and genetically modified reporter cell lines, have greatly expanded the scope of in vitro toxicology. Other significant progress in the area of human-induced pluripotent stem cells (hiPSCs) (Asgari et al., 2010; Schwartz et al., 2014; Shinde et al., 2016; Shtrichman, Germanguz and Itskovitz-Eldor, 2013) is allowing the application of patient and disease-specific hiPSCs (Ghodsizadeh et al., 2010; McCracken et al., 2014; Siller et al., 2013). Moreover, the tools of precise genome editing with engineered nucleases, such as the zinc finger nucleases (zfns), the transcription activator-like effecter nucleases (talens) and, more …

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The Potential Of Organ On Chip Technology For Replacing Animal Testing, Malcolm Wilkinson Jan 2019

The Potential Of Organ On Chip Technology For Replacing Animal Testing, Malcolm Wilkinson

Human Clinical Trials Collection

The term organ on a chip is used to describe the latest stage of development of in vitro cell culture technology. Figure 26.1 shows its steady development since the 1960s. Each step forward has improved our ability to model human-clinical response to new drugs or therapies and has enabled safety risk assessment of existing cosmetics, personal care products, or other chemicals in the environment. Scientific evidence that the predictive power of in vitro tests is superior to the use of animals will trigger a major shift in the way that medical research, in many areas, is carried out. In this …

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Recent Developments In Alternatives To Animal Testing, Katy Taylor Jan 2019

Recent Developments In Alternatives To Animal Testing, Katy Taylor

Application of Alternative Methods Collection

Methods that replace techniques that use live animals, or methods of testing substances without live animal use, are known as alternatives, replacements or non-animal methods. Some prefer the term advanced technologies given the fact that they often rely on more sophisticated technology and are more human- relevant than the animal test they replace (see Langley et al., 2015). There have been efforts to replace animal tests since the 1960s. Significant progress initially came in replacing animals used to diagnose human disease; to produce biological drugs (such as vaccines); and to safety test batches of these drugs as they were produced. …

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Behavioral Research On Captive Animals: Scientific And Ethical Concerns, Kimberley Jayne, Adam See Jan 2019

Behavioral Research On Captive Animals: Scientific And Ethical Concerns, Kimberley Jayne, Adam See

Morality and Ethics of Animal Experimentation Collection

The first half of this chapter focuses exclusively on animals that are used in laboratory behavioral research to model wild behavior, what is typically involved, problems associated with this practice, and how behavioral research has revealed scientific problems in the animal model. The second half of this chapter then addresses the ethical questions of whether scientific curiosity of animal behavior in general provides any justification for carrying out this research in this first place, with specific focus on non-human primates (nhps).

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When Is An Alternative Not An Alternative? Supporting Progress For Absolute Replacement Of Animals In Science, Craig Redmond Jan 2019

When Is An Alternative Not An Alternative? Supporting Progress For Absolute Replacement Of Animals In Science, Craig Redmond

Humane Science Movement Collection

This chapter addresses some of the areas in which animals are still used within “alternatives”-based research and calls on animal welfare and in vitro organizations to lead the debate and encourage absolute replacement of animal use in research. Without this, progress to end animal research will always remain limited, despite the paradigm shift seen in recent decades.

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