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Washington University School of Medicine

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Phenotypic And Gene Expression Changes Among Clonal Type I Strains Of Toxoplasma Gondit, Asis Khan, Michael S. Behnke, Ildiko R. Dunay, Michael W. White, L. David Sibley Jan 2009

Phenotypic And Gene Expression Changes Among Clonal Type I Strains Of Toxoplasma Gondit, Asis Khan, Michael S. Behnke, Ildiko R. Dunay, Michael W. White, L. David Sibley

Open Access Publications

No abstract provided.


Chitinases Are Essential For Sexual Development But Not Vegetative Growth In Cryptococcus Neoformans, Lorina G. Baker, Charles A. Sprecht, Jennifer K. Lodge Jan 2009

Chitinases Are Essential For Sexual Development But Not Vegetative Growth In Cryptococcus Neoformans, Lorina G. Baker, Charles A. Sprecht, Jennifer K. Lodge

Open Access Publications

No abstract provided.


Comparative Genomics Of Protoploid Saccharomycetaceae, Mark Johnston, Robert S. Fulton, Patrick Minx, Richard Wilson, Et Al Jan 2009

Comparative Genomics Of Protoploid Saccharomycetaceae, Mark Johnston, Robert S. Fulton, Patrick Minx, Richard Wilson, Et Al

Open Access Publications

No abstract provided.


Genome-Wide Identification And Analysis Of Small Rnas Originated From Natural Antisense Transcripts In Oryza Sativa, Xuefeng Zhou, Ramanjulu Sunkar, Hailing Jin, Jian-Kang Zhu, Weixiong Zhang Jan 2009

Genome-Wide Identification And Analysis Of Small Rnas Originated From Natural Antisense Transcripts In Oryza Sativa, Xuefeng Zhou, Ramanjulu Sunkar, Hailing Jin, Jian-Kang Zhu, Weixiong Zhang

Open Access Publications

No abstract provided.


Ompa Of Uropathogenic Escherichia Coli Promotes Postinvasion Pathogenesis Of Cystitis, Tracy F. Nicholson, Kristin M. Watts, David A. Hunstad Jan 2009

Ompa Of Uropathogenic Escherichia Coli Promotes Postinvasion Pathogenesis Of Cystitis, Tracy F. Nicholson, Kristin M. Watts, David A. Hunstad

Open Access Publications

No abstract provided.


Structural Determinants Of Autoproteolysis Of The Haemophilus Influenzae Hap Autotransporter, Roma Kenjale, Guoyu Meng, Doran L. Fink, Twyla Juehne, Tomoo Ohashi, Harold P. Erickson, Gabriel Waksman, Joseph W. St. Geme Iii Jan 2009

Structural Determinants Of Autoproteolysis Of The Haemophilus Influenzae Hap Autotransporter, Roma Kenjale, Guoyu Meng, Doran L. Fink, Twyla Juehne, Tomoo Ohashi, Harold P. Erickson, Gabriel Waksman, Joseph W. St. Geme Iii

Open Access Publications

No abstract provided.


Requirements Of Hsp104p Activity And Sis1p Binding For Propagation Of The [Rnq+] Prion, J. Patrick Bardill, Jennifer E. Dulle, Jonathan R. Fisher, Heather L. True Jan 2009

Requirements Of Hsp104p Activity And Sis1p Binding For Propagation Of The [Rnq+] Prion, J. Patrick Bardill, Jennifer E. Dulle, Jonathan R. Fisher, Heather L. True

Open Access Publications

No abstract provided.


The Many Faces Of Ret Dysfunction In Kidney, Sanjay Jain Jan 2009

The Many Faces Of Ret Dysfunction In Kidney, Sanjay Jain

Open Access Publications

No abstract provided.


Washington University School Of Medicine Bulletin, 2009 Jan 2009

Washington University School Of Medicine Bulletin, 2009

Washington University School of Medicine Bulletins

No abstract provided.


Lrp1 Shedding In Human Brain: Roles Of Adam10 And Adam17, Qiang Liu, Juan Zhang, Hien Tran, Marcel M. Verbeek, Karina Reiss, Steven Estus, Guojun Bu Jan 2009

Lrp1 Shedding In Human Brain: Roles Of Adam10 And Adam17, Qiang Liu, Juan Zhang, Hien Tran, Marcel M. Verbeek, Karina Reiss, Steven Estus, Guojun Bu

ICTS Faculty Publications

No abstract provided.


Outlook Magazine, Winter 2009 Jan 2009

Outlook Magazine, Winter 2009

Outlook Magazine

No abstract provided.


Outlook Magazine, Fall 2009 Jan 2009

Outlook Magazine, Fall 2009

Outlook Magazine

No abstract provided.


Outlook Magazine, Summer 2009 Jan 2009

Outlook Magazine, Summer 2009

Outlook Magazine

No abstract provided.


Outlook Magazine, Spring 2009 Jan 2009

Outlook Magazine, Spring 2009

Outlook Magazine

No abstract provided.


Predicting Music Enjoyment In Cochlear Implant Users, Rose Bradley Jan 2009

Predicting Music Enjoyment In Cochlear Implant Users, Rose Bradley

Independent Studies and Capstones

Most cochlear implant (CI) users perceive music poorly. Little is known, however, about the musical enjoyment received by CI users. The author examined possible relationships between musical enjoyment and music perception tasks through the use of 1) multiple musical tests, and 2) two groups of listeners: normal-hearing (NH) listeners with a CI-simulation and actual CI users. The two groups’ performances are compared to determine whether NH participants listening to music via CI-simulation software are a good model for actual CI users for perceiving music.


Role Of Alpha Synuclein In Noise Induced Hearing Loss, Melissa Mooney Jan 2009

Role Of Alpha Synuclein In Noise Induced Hearing Loss, Melissa Mooney

Independent Studies and Capstones

The recent discovery of the contribution of alpha synuclein in the auditory system prompted further investigation of its functional role. Auditory brainstem response (ABR) and gap detection testing were completed on wild-type and transgenic M83 mice to assess the role of alpha synuclein in noise-induced hearing loss and central auditory function.


Marginal Cell Density In Young And Old Cba/J And Cba/Caj Mice, Ashley Dahl Jan 2009

Marginal Cell Density In Young And Old Cba/J And Cba/Caj Mice, Ashley Dahl

Independent Studies and Capstones

The goal of the present study was to compare aging characteristics of the cochlear lateral wall in inbred mouse strains (CBA/J and CBA/CaJ) having very different endocochlear potential (EP)-versus-age profiles to see which anatomic differences might predict their EP differences.


Immunohistochemistry Of Synergistic Effects Of Kanamycin And Furosemide In The Murine Model, Katherine Gorton Jan 2009

Immunohistochemistry Of Synergistic Effects Of Kanamycin And Furosemide In The Murine Model, Katherine Gorton

Independent Studies and Capstones

Adult CBA/CaJ mice were injected with large single dose of both kanamycin and furosemide in order to study hair cell lesion and macrophage recruitment within the cochlea.


Efficacy Of 1000 Hz Tympanometry In Infants Birth To 4 Months Of Age: A Follow Up Study, Jamie Glater Jan 2009

Efficacy Of 1000 Hz Tympanometry In Infants Birth To 4 Months Of Age: A Follow Up Study, Jamie Glater

Independent Studies and Capstones

Interpretation of 1000 Hz tympanometry is not standardized. Several compensated and uncompensated measures were analyzed and compared to otologic findings. Results of auditory brainstem testing and otoacoustic emissions were considered to better obtain middle ear status. Findings were inconclusive due to small sample size.


In Vitro And Murine Efficacy And Toxicity Studies Of Nebulized Scc1, A Methylated Caffeine-Silver(I) Complex, For Treatment Of Pulmonary Infections, Carolyn L. Cannon, Lisa A. Hogue, Ravy K. Vajravelu, George H. Capps, Aida Ibricevic, Khadijah M. Hindi, Aysegul Kascatan-Nebioglu, Michael J. Walter, Steven L. Brody, Wiley J. Youngs Jan 2009

In Vitro And Murine Efficacy And Toxicity Studies Of Nebulized Scc1, A Methylated Caffeine-Silver(I) Complex, For Treatment Of Pulmonary Infections, Carolyn L. Cannon, Lisa A. Hogue, Ravy K. Vajravelu, George H. Capps, Aida Ibricevic, Khadijah M. Hindi, Aysegul Kascatan-Nebioglu, Michael J. Walter, Steven L. Brody, Wiley J. Youngs

Open Access Publications

No abstract provided.


Contribution Of Autolysin And Sortase A During Enterococcus Faecalis Dna-Dependent Biofilm Development, Pascale S. Guiton, Chia S. Hung, Kimberly A. Kline, Robyn Roth, Andrew L. Kau, Ericka Hayes, John Heuser, Karen W. Dodson, Michael G. Caparon, Scott J. Hultgren Jan 2009

Contribution Of Autolysin And Sortase A During Enterococcus Faecalis Dna-Dependent Biofilm Development, Pascale S. Guiton, Chia S. Hung, Kimberly A. Kline, Robyn Roth, Andrew L. Kau, Ericka Hayes, John Heuser, Karen W. Dodson, Michael G. Caparon, Scott J. Hultgren

Open Access Publications

No abstract provided.


Herpes Zoster Risk Factors In A National Cohort Of Veterans With Rheumatoid Arthritis, Jay R. Mcdonald, Angelique L. Zeringue, Liron Caplan, Prabha Ranganathan, Hong Xian, Thomas E. Burroughs, Victoria J. Fraser, Fran Cunningham, Seth A. Eisen Jan 2009

Herpes Zoster Risk Factors In A National Cohort Of Veterans With Rheumatoid Arthritis, Jay R. Mcdonald, Angelique L. Zeringue, Liron Caplan, Prabha Ranganathan, Hong Xian, Thomas E. Burroughs, Victoria J. Fraser, Fran Cunningham, Seth A. Eisen

ICTS Faculty Publications

No abstract provided.


The Neurofibromatosis 2 Protein, Merlin, Regulates Glial Cell Growth In An Erbb2- And Src-Dependent Manner, S. Sean Houshmandi, Ryan J. Emnett, Marco Giovannini, David H. Gutmann Jan 2009

The Neurofibromatosis 2 Protein, Merlin, Regulates Glial Cell Growth In An Erbb2- And Src-Dependent Manner, S. Sean Houshmandi, Ryan J. Emnett, Marco Giovannini, David H. Gutmann

Open Access Publications

No abstract provided.


A Common Role For Atg16l1, Atg5 And Atg7 In Small Intestinal Paneth Cells And Crohn Disease, Ken Cadwell, Khushbu K. Patel, Masaaki Komatsu, Herbert W. Virgin Iv, Thaddeus S. Stappenbeck Jan 2009

A Common Role For Atg16l1, Atg5 And Atg7 In Small Intestinal Paneth Cells And Crohn Disease, Ken Cadwell, Khushbu K. Patel, Masaaki Komatsu, Herbert W. Virgin Iv, Thaddeus S. Stappenbeck

Open Access Publications

No abstract provided.


Mrn Complex Function In The Repair Of Chromosomal Rag-Mediated Dna Double-Strand Breaks, Beth A. Helmink, Andrea L. Bredemeyer, Baeck-Seung Lee, Ching-Yu Huang, Girdhar G. Sharma, Laura M. Walker, Jeffrey J. Bednarski, Wan-Ling Lee, Tej K. Pandita, Craig H. Bassing, Barry P. Sleckman Jan 2009

Mrn Complex Function In The Repair Of Chromosomal Rag-Mediated Dna Double-Strand Breaks, Beth A. Helmink, Andrea L. Bredemeyer, Baeck-Seung Lee, Ching-Yu Huang, Girdhar G. Sharma, Laura M. Walker, Jeffrey J. Bednarski, Wan-Ling Lee, Tej K. Pandita, Craig H. Bassing, Barry P. Sleckman

Open Access Publications

The Mre11-Rad50-Nbs1 (MRN) complex functions in the repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) at postreplicative stages of the cell cycle. During HR, the MRN complex functions directly in the repair of DNA DSBs and in the initiation of DSB responses through activation of the ataxia telangiectasia-mutated (ATM) serine-threonine kinase. Whether MRN functions in DNA damage responses before DNA replication in G0/G1 phase cells has been less clear. In developing G1-phase lymphocytes, DNA DSBs are generated by the Rag endonuclease and repaired during the assembly of antigen receptor genes by the process of V(D)J recombination. Mice and …


Histone H2ax Stabilizes Broken Dna Strands To Suppress Chromosome Breaks And Translocations During V(D)J Recombination, Bu Yin, Velibor Savic, Marisa M. Juntilla, Andrea L. Bredemeyer, Katherine S. Yang-Iott, Beth A. Helmink, Gary A. Koretzky, Barry P. Sleckman, Craig H. Bassing Jan 2009

Histone H2ax Stabilizes Broken Dna Strands To Suppress Chromosome Breaks And Translocations During V(D)J Recombination, Bu Yin, Velibor Savic, Marisa M. Juntilla, Andrea L. Bredemeyer, Katherine S. Yang-Iott, Beth A. Helmink, Gary A. Koretzky, Barry P. Sleckman, Craig H. Bassing

Open Access Publications

No abstract provided.


An Electrostatic Switch Displaces Phosphatidylinositol Phosphate Kinases From The Membrane During Phagocytosis, Gregory D. Fairn, Koji Ogata, Roberto J. Botelho, Philip D. Stahl, Richard A. Anderson, Pietro De Camilli, Tobias Meyer, Shoshana Wodak, Sergio Grinstein Jan 2009

An Electrostatic Switch Displaces Phosphatidylinositol Phosphate Kinases From The Membrane During Phagocytosis, Gregory D. Fairn, Koji Ogata, Roberto J. Botelho, Philip D. Stahl, Richard A. Anderson, Pietro De Camilli, Tobias Meyer, Shoshana Wodak, Sergio Grinstein

Open Access Publications

No abstract provided.


Skin-Derived Tslp Triggers Progression From Epidermal- Barrier Defects To Asthma, Shadmehr Demehri, Mitsuru Morimoto, Michael J. Holtzman, Raphael Kopan Jan 2009

Skin-Derived Tslp Triggers Progression From Epidermal- Barrier Defects To Asthma, Shadmehr Demehri, Mitsuru Morimoto, Michael J. Holtzman, Raphael Kopan

Open Access Publications

No abstract provided.


Capturing A Flavivirus Pre-Fusion Intermediate, Barbel Kaufmann, Paul R. Chipman, Heather A. Holdaway, Syd Johnson, Daved H. Fremont, Richard J. Kuhn, Michael S. Diamond, Michael G. Rossmann Jan 2009

Capturing A Flavivirus Pre-Fusion Intermediate, Barbel Kaufmann, Paul R. Chipman, Heather A. Holdaway, Syd Johnson, Daved H. Fremont, Richard J. Kuhn, Michael S. Diamond, Michael G. Rossmann

Open Access Publications

No abstract provided.


Helminth Genomics: The Implications For Human Health, Paul J. Brindley, Makedonka Mitreva, Elodie Ghedin, Sara Lustigman Jan 2009

Helminth Genomics: The Implications For Human Health, Paul J. Brindley, Makedonka Mitreva, Elodie Ghedin, Sara Lustigman

Open Access Publications

No abstract provided.