Digital Commons Network^™

Role Of Rpm-1 In A C. Elegans Apoe4 Alzheimer’S Disease Model, Lucille Mcdonald

Biomedical Engineering and Sciences Student Publications

Alzheimer’s Disease (AD) is characterized by the aggregation of β-amyloid plaques. The ε4 allele of APOE (APOE4) is linked to increased plaque formation in AD. Therefore, identifying genetic modifiers of APOE4 could present novel drug targets for AD treatment.

Assessing Developmental Neurotoxicity Due To Pyrethroid Insecticide Exposure In C. Elegans, Katharine Boyd, Timothy A. Crombie

Biomedical Engineering and Sciences Student Publications

Pyrethroids are a type of insecticide widely used in agriculture and public health programs. These insecticides disrupt neuronal signaling in target insects through voltage-gated sodium channels and have been linked to cardiovascular and neurological disease in humans.The nervous system of the nematode Caenorhabditis elegans is fully mapped, and specific behavioral circuits can be tested, making it a powerful model for studying neurotoxicity. Because the primary target of pyrethroids is not conserved in C. elegans, secondary mechanisms of pyrethroid neurotoxicity can be identified by testing whether specific behavioral circuits are affected.

Dual-Lev: A Dual-Axis Ultrasonic Acoustic Levitator, Trevor Hennington, Alyx Mason

Aerospace, Physics, and Space Science Student Publications

sound waves to create a standing wave, where regions of high and low pressure form stable nodes that can trap small objects. The upward acoustic radiation force at these nodes balances gravity, allowing the object to float in midair. This technology is applicable in various fields such as chemistry, biological engineering, and sub-gravity simulation. It can also be used for drop dynamics studies, crystallization, and

Unf Student Research Symposium Conference Program Spring 2026, Office Of Undergraduate Research, Graduate School, Digital Humanities Institute, Hicks Honors College

UNF Student Research Symposium

Formerly known as SOARS, ARISE and U-GLIDE, the Student Research Symposium is a multi-disciplinary conference series at the University of North Florida (UNF) in which undergraduate and graduate students showcase their research projects during the fall, spring and summer semesters. Research at UNF includes inquiry and investigation in all forms. Communication of knowledge produced through student research can be presented in poster format or as an oral presentation at the Student Research Symposium in a welcoming environment. This is an excellent opportunity for students to refine their presentation skills through interaction with peers and faculty as they explain their projects, …

Interview No. 1818, Julianna Esparza

Combined Interviews

Julianna Esparza reflects on growing up in Segundo Barrio and how those experiences shaped her identity, activism and nonprofit work. This interview preserves personal memories and reflections about community transformation, education, and activism.

Photochemical Activation Of Cyanine-Based Nanogels For Controlled Drug Delivery, Presley Clary

Chemistry and Chemical Engineering Student Publications

Cyanines are highly conjugated molecules with useful properties, such as ease of aggregation and fluorescence. In this project, they were incorporated into an acrylamide-based nanogel made through organic synthesis to exploit these properties for controlled drug delivery. Exposing the nanogel to nearinfrared (NIR) light causes it to react with reactive oxygen species (ROS), forming an unstable intermediate. The intermediate splits into two fragments, releasing the nanogel's cargo.1 The cargo, temozolomide, is an alkylating agent which can be used to disrupt the DNA of cancer cells.

Phenotype Variations Among Chlamydomonas Reinhardtii Under Quorum-Sensing Conditions, Marcel Pedrosa

Biomedical Engineering and Sciences Student Publications

Quorum sensing (QS) is a cell-to-cell communication system that allows unicellular microorganisms like the eukaryote C. reinhardtii to regulate phenotypic switching as a function of cell density due to the accumulation of signaling molecules.  The goal of this study is to evaluate whether QS in C. reinhardtii is regulated by nutrient availability. We propose that in a nutrient-limited environment (low nitrogen TAP (N-TAP)), cells of C. reinhardtii (cc124) would adjust their motility-driven dispersion of cells and upregulate chlorophyll and carotenoid production per cell.

Advancing Common Fixed Point Theorems In Bipolar Fuzzy-2 Metric Space And Applications In Nonlinear Analysis, Rajesh Kumar Saini, Mukesh Kushwaha

Neutrosophic Sets and Systems

This study advances common fixed point theorems (CFPT) in bipolar fuzzy-2 metric space (BF2MS) and explores their applications in nonlinear analysis. BF2MS generalizes traditional metric and fuzzy metric spaces (FMS) by incorporating dualistic relationships, allowing the representation of both attraction and repulsion effects. We extend classical fixed point theorems (FPTs) to BF2MS, establishing conditions for the existence of common fixed points (CFPs). The study's applications span nonlinear analysis, stability analysis, control theory, and multi-criteria decision-making under uncertainty. Our findings refine existing results and provide practical real-world applications, supported by numerical examples, enhancing fuzzy mathematics and nonlinear systems modeling.

How Pollinator Populations Can Impact Chronic Disease Risk, Kylee Cubbison

Honors Projects

This project investigates how pollinator populations can impact chronic disease risk. Pollinator populations are declining, which can have serious implications for human health. Declining pollinator populations can limit healthy food production and affordability. Poor nutrition is a major risk factor for most chronic diseases. Less healthy food available for people to consume can negatively impact diets and increase the risk of developing chronic diseases. This project aims to address a potential gap in research existing on this specific topic regarding pollinator populations and human chronic disease risk. A brochure targeted towards educating the general public on this topic was created …

Exploring Marital Resilience Through The Lived Experiences And Perception Of Spousal Support During Events Of Shared Stressors, Prince-James Smith

Walden Dissertations and Doctoral Studies

Marital resilience during shared stressors remains insufficiently understood, particularly when both spouses are simultaneously affected by the same external stressor and must adapt together over time. The purpose of this qualitative phenomenological study was to explore marital resilience through the lived experiences and perceptions of spousal support during shared stressors among individuals who had been legally married for 10 years or more, with specific attention to how participants described the shift from solo coping to dyadic coping over time. Bowlby’s attachment theory provided the theoretical foundation, and Senge’s learning organization theory served as the conceptual framework. Participants included 18 legally …

Molecular Cloning And Bioinformatic Analysis Of S. Aureus Surface Antigens For Chimera Vaccine Development, Jack Wood, Ruben Ferreira Paiva, Micah David, Juliette Tinker

2026 Undergraduate Research Showcase

Staphylococcus aureus is a primary cause of bovine mastitis, which has significant agricultural and economic implications, affecting the health of cattle and dairy production globally. As antibiotic resistance increases, providing a preventive vaccine is essential to alleviate the economic burden and improve herd health. The goal of our research is to identify and clone immunogenic S. aureus genes that can serve as components of a future cholera toxin chimera subunit vaccine targeting S. aureus infections. The target genes, which encode potential surface antigens, were amplified by Polymerase Chain Reaction (PCR) and directionally ligated into a high-expression vector that will create …

The Effect Of Burnout On Intention To Resign Among Adult Protective Services Investigators, Derek Frank Wachter

Walden Dissertations and Doctoral Studies

Adult Protective Services (APS) workers play a crucial role in providing care, support, and services to older and adult clients with special needs. There was a lack of empirical data on the long-term retention of APS investigators and on how burnout affects their intentions to resign. Departments consistently rely on a cycle of using newer, less experienced investigators who may not know about community and state services or department policies and procedures to connect clients. The purpose of this quantitative correlational study was to examine the relationship between personal, work-related, and client-related burnout and APS investigators’ intention to resign. Data …

Exploring The Experiences Of Faculty Members Educating Students Virtually Post-Covid-19, Raven Ashley Richardson

Walden Dissertations and Doctoral Studies

The COVID-19 pandemic significantly disrupted higher education, requiring institutions to rapidly transition to virtual learning environments and leaving faculty to manage increased workloads, stress, and challenges related to instructional quality and student engagement. The problem in this study is traditional faculty continue to experience these challenges in the post pandemic academic landscape, with implications for faculty wellbeing and student success. The purpose of this qualitative generic study was to explore experiences of traditional college faculty members educating students while transitioning from in-person to virtual learning environments post-COVID-19. Guided by the ecological systems theory, multilevel influences on faculty experiences were examined. …

The Lived Experiences Of The Strong Black Woman Cultural Convention On Black Women Counselors’ Emotional Intelligence, Pranati Walker

Walden Dissertations and Doctoral Studies

Emotional intelligence (EI) is a critical competency for counselors due to the relational and emotionally demanding nature of counseling. Although existing literature explored EI among Black women broadly, limited research examined the experiences of Black women counselors (BWCs). This descriptive phenomenological study was guided by the philosophy of phenomenology and explored the lived experiences and impact of the SBW cultural convention on the EI of BWCs. The researcher explored the lived experiences of BWCs regarding the SBW cultural convention and its impact on emotional intelligence. Participant data from eight semi-structured interviews were collected. The participants identified as female gender identity, …

Environmental Dna Barcoding For Non-Model Organisms: Challenges And Outcomes Of Developing Barcodes For Freshwater Mussels, Nicholas Duellman

Longwood Senior Theses

Freshwater mussels are a keystone species providing crucial ecosystem services and river composition resiliency. Globally, they remain one of the most imperiled invertebrate groups, facing threats of water quality declines and urban development. Traditional field sampling can often be laborious and ineffective in surveying rare species’ distributions. Anecdotal evidence suggests the presence of freshwater mussels within the Appomattox River; the specifics of population sizes and suitable habitat remains an open question. Environmental DNA (eDNA) usage in conservation ecology has increased dramatically within the past two decades, being a far less invasive and cost-demanding option than traditional surveys. In an effort …

Inhibition Of Cyclophilin D Rescues Cardiac Function And Bioenergetic Defects Caused By Neonatal Hypoxia, Jonathan R. Burris, Gisela Beutner, Min Yee, Bartholomew V. Simon, Michael F. Swartz, Kathryn B. Boudreau, Ethan D. Cohen, Chaitanya A. Kulkarni, Prottoy Hasan, Hongyue Wang, Karen L. De Mesy Bentley, György Hajnóczky, George M. Alfieris, Eric M. Small, Paul S. Brookes, Michael A. O'Reilly, George A. Porter

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Increased oxygen levels at birth regulate myocyte bioenergetic and structural maturation controlled by mitochondrial cyclophilin D (CypD). We evaluated mechanisms of neonatal hypoxic cardiac dysfunction by exposing neonatal mice to 12% oxygen and studied cardiac bioenergetics, myocyte maturation, and function. Hypoxia decreased the activity/assembly of electron transport chain complex I, uncoupled oxidative phosphorylation, increased proliferation, decreased differentiation, increased ventricular mass, and decreased cardiac function. CypD inhibition rescued most hypoxia-mediated effects and increased cardiac function. In conclusion, neonatal hypoxia alters cardiac bioenergetics, myocyte maturation, and cardiac function through CypD-dependent pathways, providing potential therapeutic targets for neonatal cardiac dysfunction.

Program And Proceedings, The Nebraska Academy Of Sciences 1880–2026: 146th Anniversary Year, One Hundred-Thirty-Sixth Annual Meeting

Nebraska Academy of Sciences: Programs and Proceedings

Program and abstracts of the proceedings for the Nebraska Academy of Sciences 136th annual meeting, 2025

Sessions

Aeronautics and Space Science

Anthropology

Biological and Medical Sciences

Earth Sciences

Ecology, Sustainability, and Environmental Science

Physics and Engineering

General Poster Session

2026 Maiben Lecture: Shifting Extremes: Understanding Nebraska’s Changing Climate and Preparing for What Lies Ahead, Deborah Bathke

2026 Friends of Science Awards: Julie Shaffer and Irina Filina

2026 C. Bertrand and Marian Othmer Schultz Colleaguate Schoalrship Award: Piper Ryschon and Bryce Reeson

In Memoriam: Paul Royster

Moving On Stage, Moving The Audience: The Overlooked Impacts Of Body Language On Performance Reception Of Classical Music, Julia Jacobsen

Student Publications and Presentations

A large focus in productions of classical music is put towards executing the music at the highest level to achieve both the composer’s and interpreter’s visions. However, modern-day musicians often overlook the importance of visually conveying their music through their emotional expressions and movements. In this paper, I will examine existing research on audience perceptions of classical music performances, utilizing highly successful musicians as examples to determine their impact on audience reception of classical music. In so doing, I hope to develop strategies for greater audience engagement that will help music students and performers increase their connection to their auditors. …

Learning The Notes: Developing Absolute Pitch, Emma Joyce

Student Publications and Presentations

Absolute pitch (AP) is the ability to identify or name a musical pitch without the aid of a reference tone. Although the concept has been known for centuries, the processes of its development remain unclear. Researchers have proposed a variety of explanations, yet despite advances in neuroscience and cognitive psychology, there is still no agreement on whether AP results from natural ability or learned experience. By understanding neurological and developmental research, reviewing existing literature, analyzing case studies, and evaluating current theories, this paper aims to identify gaps in previous research and suggests a new approach for developing AP in young …

Preserving The Untold Stories: Leveraging Emerging Technologies (Ai And Machine Learning) For Archiving Hidden Histories Of Children And Families Impacted By The Little Rock School Integration Crisis, Oluseyi Noah Adebanjo

Theses and Dissertations

This thesis challenges the dominant narrative of the Little Rock School Integration Crisis by recovering the hidden histories of families and siblings who made integration possible but have been systematically overlooked by historians. While existing scholarship focuses on the Little Rock Nine as individual heroes, this research demonstrates that integration was fundamentally a family crisis requiring collective decision-making, economic sacrifice, and multigenerational support networks. Through close reading of published memoirs, newspaper clippings, school board minutes, and original oral history interviews with Phyllis Brown and Dr. Sybil Jordan Hampton, this study reveals how approximately 200 eligible families were systematically reduced to …

A Cross-Sectional Study To Explore Healthcare Providers’ Wellness: Current Challenges & Gut Health, Linda Liu, Simi Joseph

Creating Healthy Work Environments (CHWE)

Background: Healthcare provider well-being is essential for high-quality patient care. However, stress, burnout, and demanding work environments negatively impact physical and mental health, including gut health. The gut-brain axis underscores the link between gastrointestinal function, stress, and well-being, yet limited research has explored gut health among healthcare professionals.

Purpose: This study assessed the prevalence of gastrointestinal symptoms among healthcare providers and examined associations with stress levels, clinical environment, and quality of life in acute and outpatient settings.

Framework: Guided by the Biopsychosocial Model, this research explored how biological, psychological, and social factors influence the well-being and gut health of healthcare …

Systematic Review Of Multi-Level Determinants And Equity Implications Of Mode Of Birth In The U.S., Abdul-Manaf Mutaru, Cynthia Nicole Lebron, Wonsuk Yoo, Alexa Parra, Lunthita Duthely, Thomas Mike O'Shea, Hudson P. Santos Jr.

Creating Healthy Work Environments (CHWE)

Background: Giving birth by surgical operation (cesarean birth) is linked to complications such as postpartum infection, rehospitalization, and respiratory issues in newborns. However, the cesarean rate remains high, accounting for 32.4% of all births in the United States (U.S.). Understanding the impact of factors beyond the individual level is crucial for developing interventions to reduce preventable cesarean births and promote health equity.

Purpose/Aim: This systematic review synthesized evidence from U.S.-based studies to identify factors beyond the maternal level that are associated with mode of birth (vaginal or cesarean).

Methods: We searched PubMed, Web of Science, PsycINFO, and CINAHL for studies …

Anterior Cruciate Ligament (Acl) Injuries In Female Athletes: Implications For Prevention And Rehabilitation, Natalie Amm

Honors Theses

Anterior cruciate ligament (ACL) injuries are among the most common lower limb injuries and pose significant physical, psychological, and long-term functional challenges for athletes. Additionally, research has suggested that females are up to eight times more likely to experience an ACL injury than their male counterparts. This increased risk is multifactorial with risks including anatomical structure, neuromuscular control, strength deficits, and hormonal fluctuations. However, the elevated risk of ACL injuries in female athletes may not solely be caused by biological differences, but also due to training programs and sports being designed around male athletes. This pushes us to change the …

Gender Bias And The Adhd Diagnosis Gap, Ashlee Depass

Student Publications and Presentations

Public conversations often question whether Attention-Deficit/Hyperactivity Disorder (ADHD) receives too many diagnoses. At the same time, many girls and women report years of struggling without recognition or support. This contrast suggests that the issue may not simply be how often clinicians diagnose ADHD, but how they recognize it and whose symptoms prompt evaluation. ADHD does not present identically across individuals. Boys frequently display hyperactive or disruptive behaviors that draw attention in school and clinical settings. Girls more commonly experience inattentiveness, emotional intensity, or internal distress that may not disrupt others in obvious ways. When adults interpret these behaviors differently, they …

The Effects Of The Opioid Crisis On Fentanyl Exhibitions, Onnalee Floriano

Student Publications and Presentations

The opioid crisis is an epidemic in which fentanyl related overdoses are becoming more common. With the increase in prescription and recreational drugs, there has been a rise in drug combinations and exhibitions in the United States. Fentanyl has been found to be combined with other opiates like heroin, cocaine, and methamphetamine, creating a higher risk of overdoses when being used recreationally. The National Forensic Laboratory Information System (NFLIS) is designed to collect drugs and understand the trends in where they are being seized. From 2015 to 2019, the NFLIS collected drugs in four groups, fentanyl alone, and fentanyl combinations …

Expression And Purification Of Mayaro Virus Nsp2 Protease, Emma Grace Tourville

Honors Capstone Projects and Theses

No abstract provided.

Simple Guide To Using Generative Artificial Intelligence Writing Tools In Research & Scholarship At Unh, Julie Simpson, Patricia Condon, Bonnie Brown, William C. Clyde, James J. Connell, Ramonda Kindle, Jennifer Miksis-Olds, Christopher Neefus, Jennifer O’Brien, Theresa Oehmke, Shantel Palacio, Allyson Ryder, Nathan A. Schwadron, John E. Sparrow, Xueting Sun, Engin Taze, May-Win Thein, Anita R. Tucker, Karen T. Van Gundy, James Wible

Integrity in Research and Scholarship

While Artificial Intelligence (AI) technologies have existed for years, the recent arrival of widespread generative AI writing tools such as ChatGPT has provoked varied reactions in the scholarly community worldwide. Undoubtedly easy access to such tools may help to level the scholarly playing field for certain groups, particularly those with limited writing skills or proficiency with English as the primary language for written and oral communication of research and scholarship. There are, however, concerns about these tools, including, but not limited to, the accuracy, consistency, and bias of the information generated, appropriate acknowledgement of source material, and the tools’ lack …

Reproductive Season And Fecundity Reassessment Of Gopher Tortoises (Gopherus Polyphemus) In Southeastern Florida, Riley Waters

Electronic Theses and Dissertations

The gopher tortoise (Gopherus polyphemus) breeding season occurs throughout spring and early summer across its distributional range, but recent research shows that in southeastern Florida, mating also occurs in the fall and winter months. This project evaluates the gopher tortoise’s extended reproductive season in southeastern Florida and female fecundity. The study, conducted at two locations in South Florida: Jupiter, FL and Boca Raton, FL, used field ultrasound equipment and radiographs to identify gravid females and determine clutch size. The data suggest a much earlier start to egg development and nesting, and the possibility of an extended egg development …

Engineering Function In Lung Biology: Integrating Imaging, Regenerative Constructs, And Functional Biodesign, Rene A Girard, Jamie Tran, Yuqing Cai, Mary C Farach-Carson, Hadi T Nia, Allison M Greaney, Laura E Niklason, Killian Hurley, Elvin Blanco, Sinem Koc-Günel, Harry Karmouty-Quintana

Faculty, Staff and Student Publications

The lung is a uniquely demanding target for regeneration because function depends on the coordinated integration of cellular diversity, three-dimensional architecture, cyclic mechanical forces, vascular perfusion, immune surveillance, and extracellular matrix remodeling. While single-cell and spatial profiling, lineage tracing, and iPSC-derived models have transformed our understanding of lung cell states and developmental potential, these descriptive approaches have also highlighted a central bottleneck: the field still lacks broadly adopted platforms to test whether engineered tissues and regenerative interventions restore function under physiologic load. In this review, we focus on emerging technologies that enable functional biodesign in lung biology by coupling engineered …

Modeling Early Human Heart Development Using An Ipsc-Based 3d Bioprinted Model Of Embryonic Heart Tube, Linqi Jin, Christian Park, Sunder Neelakantan, Shweta Karnik, Arnab Dey, Sarah Fineman, Roshni Nandwani, Carmen J Gil, Boeun Hwang, Melissa A Cadena, Vani Sridhar, Jing Wang, Yuxiao Wu, Connor J Evans, Lan Li, Sarah Rezapourdamanab, Mehdi Salar Amoli, Martin L Tomov, Ryan K Roeder, Reza Avazmohammadi, Lakshmi Prasad Dasi, Hanjoong Jo, Eric Weeks, Holly D Bauser-Heaton, Sean M Wu, Vahid Serpooshan

Faculty, Staff and Student Publications

Human heart development depends on tightly coordinated genetic programs and biomechanical cues, yet the underlying cell-microenvironment interactions remain poorly understood because the developing heart is difficult to study in utero and accurate experimental models are lacking. Recent advances in stem cell biology and three-dimensional (3D) bioprinting now allow the construction of human tissue analogues with defined structure and function. Here we show a perfusable 3D bioprinted model of the human embryonic heart tube composed of layered myocardium, cardiac jelly, and endocardium. Human induced pluripotent stem cell-derived cardiomyocytes and endothelial cells are cultured under controlled flow conditions, producing constructs with high …