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Washington University School of Medicine

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Business Process Flow Diagrams In Tissue Bank Informatics System Design, And Identification And Communication Of Best Practices: The Pharmaceutical Industry Experience, Sarah A. Mcdonald, Elizabeth Velasco, Nicholas T. Ilasi Jan 2010

Business Process Flow Diagrams In Tissue Bank Informatics System Design, And Identification And Communication Of Best Practices: The Pharmaceutical Industry Experience, Sarah A. Mcdonald, Elizabeth Velasco, Nicholas T. Ilasi

Open Access Publications

No abstract provided.


Glycosaminoglycans In Human And Bovine Serum: Detection Of Twenty-Four Heparan Sulfate And Chondroitin Sulfate Motifs Including A Novel Sialic Acid-Modified Chondroitin Sulfate Linkage Hexasaccharide, Hong Lu, Lynda M. Mcdowell,, Daniel R. Studelska, Lijuan Zhang Jan 2010

Glycosaminoglycans In Human And Bovine Serum: Detection Of Twenty-Four Heparan Sulfate And Chondroitin Sulfate Motifs Including A Novel Sialic Acid-Modified Chondroitin Sulfate Linkage Hexasaccharide, Hong Lu, Lynda M. Mcdowell,, Daniel R. Studelska, Lijuan Zhang

Open Access Publications

No abstract provided.


Biogeography And Habitat Modelling Of High-Alpine Bacteria, Andrew J. King, Kristen R. Freeman, Katherine F. Mccormick, Ryan C. Lynch, Catherine Lozupone, Rob Knight, Steven K. Schmidt Jan 2010

Biogeography And Habitat Modelling Of High-Alpine Bacteria, Andrew J. King, Kristen R. Freeman, Katherine F. Mccormick, Ryan C. Lynch, Catherine Lozupone, Rob Knight, Steven K. Schmidt

Open Access Publications

No abstract provided.


Brentuximab Vedotin (Sgn-35) For Relapsed Cd30-Positive Lymphomas, Anas Younes, Nancy L. Bartlett, John P. Leonard, Dana A. Kennedy, Carmel M. Lynch, Eric L. Sievers, Andres Forero-Torres Jan 2010

Brentuximab Vedotin (Sgn-35) For Relapsed Cd30-Positive Lymphomas, Anas Younes, Nancy L. Bartlett, John P. Leonard, Dana A. Kennedy, Carmel M. Lynch, Eric L. Sievers, Andres Forero-Torres

Open Access Publications

No abstract provided.


Clustering Of Trauma And Associations With Single And Co-Occurring Depression And Panic Attack Over Twenty Years, Vivia V. Mccutcheon, Andrew C. Heath, Elliot C. Nelson, Kathleen K. Bucholz, Pamela A.F. Madden, Nicholas G. Martin Jan 2010

Clustering Of Trauma And Associations With Single And Co-Occurring Depression And Panic Attack Over Twenty Years, Vivia V. Mccutcheon, Andrew C. Heath, Elliot C. Nelson, Kathleen K. Bucholz, Pamela A.F. Madden, Nicholas G. Martin

Open Access Publications

No abstract provided.


A Snp Discovery Method To Assess Variant Allele Probability From Next-Generation Resequencing Data, Yufeng Shen, Zhengzheng Wan, Cristian Coarfa, Rafal Drabek, Lei Chen, Elizabeth A. Ostrowski, Yue Liu, George M. Weinstock, David A. Wheeler, Richard A. Gibbs, Fuli Yu Jan 2010

A Snp Discovery Method To Assess Variant Allele Probability From Next-Generation Resequencing Data, Yufeng Shen, Zhengzheng Wan, Cristian Coarfa, Rafal Drabek, Lei Chen, Elizabeth A. Ostrowski, Yue Liu, George M. Weinstock, David A. Wheeler, Richard A. Gibbs, Fuli Yu

Open Access Publications

No abstract provided.


Genome Assembly Quality: Assessment And Improvement Using The Neutral Indel Model, Stephen Meader, Ladeana W. Hillier, Devin Locke, Chris P. Ponting, Gerton Lunter Jan 2010

Genome Assembly Quality: Assessment And Improvement Using The Neutral Indel Model, Stephen Meader, Ladeana W. Hillier, Devin Locke, Chris P. Ponting, Gerton Lunter

Open Access Publications

No abstract provided.


Construction Of Recombinant Attenuated Salmonella Enterica Serovar Typhimurium Vaccine Vector Strains For Safety In Newborn And Infant Mice, Bronwyn M. Gunn, Soo-Young Wanda, Dana Burshell, Caihong Wang, Roy Curtiss Iii Jan 2010

Construction Of Recombinant Attenuated Salmonella Enterica Serovar Typhimurium Vaccine Vector Strains For Safety In Newborn And Infant Mice, Bronwyn M. Gunn, Soo-Young Wanda, Dana Burshell, Caihong Wang, Roy Curtiss Iii

Open Access Publications

No abstract provided.


Enterococcal Biofilm Formation And Virulence In An Optimized Murine Model Of Foreign Body-Associated Urinary Tract Infections, Pascale S. Guiton, Chia S. Hung, Lynn E. Hancock, Michael G. Caparon, Scott J. Hultgren Jan 2010

Enterococcal Biofilm Formation And Virulence In An Optimized Murine Model Of Foreign Body-Associated Urinary Tract Infections, Pascale S. Guiton, Chia S. Hung, Lynn E. Hancock, Michael G. Caparon, Scott J. Hultgren

Open Access Publications

No abstract provided.


Characterization Of A Novel Murine Model Of Staphylococcus Saprophyticus Urinary Tract Infection Reveals Roles For Ssp And Sdri In Virulence, Kimberly A. Kline, Molly A. Ingersoll, Hailyn V. Nielsen, Turkan Sakinc, Michael G. Caparon, Scott J. Hultgren Jan 2010

Characterization Of A Novel Murine Model Of Staphylococcus Saprophyticus Urinary Tract Infection Reveals Roles For Ssp And Sdri In Virulence, Kimberly A. Kline, Molly A. Ingersoll, Hailyn V. Nielsen, Turkan Sakinc, Michael G. Caparon, Scott J. Hultgren

Open Access Publications

No abstract provided.


Virulence Plasmid Harbored By Uropathogenic Escherichia Coli Functions In Acute Stages Of Pathogenesis, Corinne K. Cusumano, Chia S. Hung, Swaine L. Chen, Scott J. Hultgren Jan 2010

Virulence Plasmid Harbored By Uropathogenic Escherichia Coli Functions In Acute Stages Of Pathogenesis, Corinne K. Cusumano, Chia S. Hung, Swaine L. Chen, Scott J. Hultgren

Open Access Publications

No abstract provided.


Expression Of The Baba Adhesin During Experimental Infection With Helicobacter Pylori, Cathy M. Styer, Lori M. Hansen, Cara L. Cooke, Amy M. Gundersen, Sung Sook Choi, Douglas E. Berg, Mohammed Benghezal, Barry J. Marshall, Richard M. Peek Jr, Thomas Boren, Jay V. Solnick Jan 2010

Expression Of The Baba Adhesin During Experimental Infection With Helicobacter Pylori, Cathy M. Styer, Lori M. Hansen, Cara L. Cooke, Amy M. Gundersen, Sung Sook Choi, Douglas E. Berg, Mohammed Benghezal, Barry J. Marshall, Richard M. Peek Jr, Thomas Boren, Jay V. Solnick

Open Access Publications

No abstract provided.


Characterization And Modulation Of The Immunosuppressive Phase Of Sepsis, Jared T. Muenzer, Christopher G. Davis, Kathy Chang, Robert E. Schmidt, W. Michael Dunne, Craig M. Coopersmith, Richard S. Hotchkiss Jan 2010

Characterization And Modulation Of The Immunosuppressive Phase Of Sepsis, Jared T. Muenzer, Christopher G. Davis, Kathy Chang, Robert E. Schmidt, W. Michael Dunne, Craig M. Coopersmith, Richard S. Hotchkiss

Open Access Publications

No abstract provided.


Nurturing The Genome: A-Type Lamins Preserve Genomic Stability, Ignacio Gonzalez-Suarez, Susana Gonzalo Jan 2010

Nurturing The Genome: A-Type Lamins Preserve Genomic Stability, Ignacio Gonzalez-Suarez, Susana Gonzalo

Open Access Publications

No abstract provided.


The Human Microbiome Harbors A Diverse Reservoir Of Antibiotic Resistance Genes, Morten O.A. Sommer, George M. Church, Gautam Dantas Jan 2010

The Human Microbiome Harbors A Diverse Reservoir Of Antibiotic Resistance Genes, Morten O.A. Sommer, George M. Church, Gautam Dantas

Open Access Publications

No abstract provided.


Type I Ifn Enhances Follicular B Cell Contribution To The T Cell-Independent Antibody Response, Cristina L. Swanson, Timothy J. Wilson, Pamela Strauch, Marco Colonna, Roberta Pelanda, Raul M. Torres Jan 2010

Type I Ifn Enhances Follicular B Cell Contribution To The T Cell-Independent Antibody Response, Cristina L. Swanson, Timothy J. Wilson, Pamela Strauch, Marco Colonna, Roberta Pelanda, Raul M. Torres

Open Access Publications

Humoral immunity to viruses and encapsulated bacteria is comprised of T cell-independent type 2 (TI-2) antibody responses that are characterized by rapid antibody production by marginal zone and B1 B cells. We demonstrate that toll-like receptor (TLR) ligands influence the TI-2 antibody response not only by enhancing the overall magnitude but also by skewing this response to one that is dominated by IgG isotypes. Importantly, TLR ligands facilitate this response by inducing type I interferon (IFN), which in turn elicits rapid and significant amounts of antigen-specific IgG2c predominantly from FO (follicular) B cells. Furthermore, we show that although the IgG2c …


Outlook Magazine, Winter 2010 Jan 2010

Outlook Magazine, Winter 2010

Outlook Magazine

No abstract provided.


Outlook Magazine, Spring 2010 Jan 2010

Outlook Magazine, Spring 2010

Outlook Magazine

No abstract provided.


Implications For Early Interventionists: Cross-Cultural And Low-Income Family Differences, Karen Elizabeth Kruse Jan 2010

Implications For Early Interventionists: Cross-Cultural And Low-Income Family Differences, Karen Elizabeth Kruse

Independent Studies and Capstones

This study examined the existing literature on current early intervention processes for children who are deaf or hard of hearing who are from low-income or minority families. The review of literature includes a framework of understanding the dynamics of low-income households and cultural differences among African Americans, Latin Americans, and American Indians.


Comparison Of Map Kinases In The Proliferation Of Chick Utricular Epithelial Cells, Meghan Kathleen Spriggs Jan 2010

Comparison Of Map Kinases In The Proliferation Of Chick Utricular Epithelial Cells, Meghan Kathleen Spriggs

Independent Studies and Capstones

Levels of activation of MAP kinase pathways and effects of inhibiting these pathways were examined in chick utricular epithelial cultures in order to determine the role of these pathways in proliferation.


Effect Of Unilateral Hearing Loss On The Speech-Evoked Auditory Brainstem Response In The Presence Of Noise, Kristin Elizabeth Musser Jan 2010

Effect Of Unilateral Hearing Loss On The Speech-Evoked Auditory Brainstem Response In The Presence Of Noise, Kristin Elizabeth Musser

Independent Studies and Capstones

Speech-evoked auditory brainstem responses (ABRs) were acquired in quiet and in the presence of noise at two study sessions to investigate 1) test-retest variability and 2) subcortical representation of speech stimuli. Participants were adults with normal hearing in both ears who listened monaurally and adults with unilateral deafness. Results indicate consistency in responses across sessions and several differences between hearing groups for magnitudes of discrete components.


Dialogue Journals: A Non-Threatening Way To Correct Written Language Errors, Sara Brooke Morrell Jan 2010

Dialogue Journals: A Non-Threatening Way To Correct Written Language Errors, Sara Brooke Morrell

Independent Studies and Capstones

The goals of the present study are: to determine if dialogue journals are an effective activity within a balanced literacy program to improve on written language errors in students who are deaf and hard of hearing.


Protein Misfolding Induces Hypoxic Preconditioning Via A Subset Of The Unfolded Protein Response Machinery, Xianrong R. Mao, C. Michael Crowder Jan 2010

Protein Misfolding Induces Hypoxic Preconditioning Via A Subset Of The Unfolded Protein Response Machinery, Xianrong R. Mao, C. Michael Crowder

Open Access Publications

No abstract provided.


The Sua5 Protein Is Essential For Normal Translational Regulation In Yeast, Changyi A. Lin, Steven R. Ellis, Heather L. True Jan 2010

The Sua5 Protein Is Essential For Normal Translational Regulation In Yeast, Changyi A. Lin, Steven R. Ellis, Heather L. True

Open Access Publications

No abstract provided.


Geobacter Uraniireducens Nikr Displays A Dna Binding Mode Distinct From Other Members Of The Nikr Family, Erin L. Benanti, Peter T. Chivers Jan 2010

Geobacter Uraniireducens Nikr Displays A Dna Binding Mode Distinct From Other Members Of The Nikr Family, Erin L. Benanti, Peter T. Chivers

Open Access Publications

No abstract provided.


Inflammatory Monocytes But Not Neutrophils Are Necessary To Control Infection With Toxoplasma Gondii In Mice, Ildiko R. Dunay, Anja Fuchs, L. David Sibley Jan 2010

Inflammatory Monocytes But Not Neutrophils Are Necessary To Control Infection With Toxoplasma Gondii In Mice, Ildiko R. Dunay, Anja Fuchs, L. David Sibley

Open Access Publications

No abstract provided.


The Isolated Pancreatic Islet As A Micro-Organ And Its Transplantation To Cure Diabetes: Celebrating The Legacy Of Paul Lacy, Stanley Misler Jan 2010

The Isolated Pancreatic Islet As A Micro-Organ And Its Transplantation To Cure Diabetes: Celebrating The Legacy Of Paul Lacy, Stanley Misler

Open Access Publications

No abstract provided.


Improved Survival With Ipilimumab In Patients With Metastatic Melanoma, Gerald P. Linette, Et Al Jan 2010

Improved Survival With Ipilimumab In Patients With Metastatic Melanoma, Gerald P. Linette, Et Al

Open Access Publications

No abstract provided.


Structural Homology Between The C-Terminal Domain Of The Papc Usher And Its Plug, Bradley Ford, Ana Toste Rêgo, Timothy J. Ragan, Jerome Pinkner, Karen Dodson, Paul C. Driscoll, Scott Hultgren, Gabriel Waksman Jan 2010

Structural Homology Between The C-Terminal Domain Of The Papc Usher And Its Plug, Bradley Ford, Ana Toste Rêgo, Timothy J. Ragan, Jerome Pinkner, Karen Dodson, Paul C. Driscoll, Scott Hultgren, Gabriel Waksman

Open Access Publications

No abstract provided.


Human Papillomavirus Types 16, 18, And 31 Serostatus And Prostate Cancer Risk In The Prostate Cancer Prevention Trial, Siobhan Sutcliffe, Raphael P. Viscidi, Cathee Till, Phyllis J. Goodman, Ashraful M. Hoque, Ann W. Hsing, Ian M. Thompson, Johnathan M. Zenilman, Angelo M. De Marzo, Elizabeth A. Platz Jan 2010

Human Papillomavirus Types 16, 18, And 31 Serostatus And Prostate Cancer Risk In The Prostate Cancer Prevention Trial, Siobhan Sutcliffe, Raphael P. Viscidi, Cathee Till, Phyllis J. Goodman, Ashraful M. Hoque, Ann W. Hsing, Ian M. Thompson, Johnathan M. Zenilman, Angelo M. De Marzo, Elizabeth A. Platz

Cancer Prevention Faculty Publications

No abstract provided.