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Washington University School of Medicine

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Bacterial Lysis Liberates The Neutrophil Migration Suppressor Ybcl From The Periplasm Of Uropathogenic Escherichia Coli, Megan E. Lau, Elizabeth S. Danka, Kristin M. Tiemann, David A. Hunstad Jan 2014

Bacterial Lysis Liberates The Neutrophil Migration Suppressor Ybcl From The Periplasm Of Uropathogenic Escherichia Coli, Megan E. Lau, Elizabeth S. Danka, Kristin M. Tiemann, David A. Hunstad

Open Access Publications

No abstract provided.


Chronic Allergic Contact Dermatitis Promotes Skin Cancer, Shadmehr Demehri, Trevor J. Cunningham, Eva A. Hurst, Andras Schaffer, David M. Sheinbein, Wayne M. Yokoyama Jan 2014

Chronic Allergic Contact Dermatitis Promotes Skin Cancer, Shadmehr Demehri, Trevor J. Cunningham, Eva A. Hurst, Andras Schaffer, David M. Sheinbein, Wayne M. Yokoyama

Open Access Publications

No abstract provided.


Reassessing The Impact Of Smoking On Preeclampsia/Eclampsia: Are There Age And Racial Differences?, Jen Jen Chang, Jerome F. Strauss Iii, Jon P. Deshazo, Fidelma B. Rigby, David P. Chelmow, George A. Macones Jan 2014

Reassessing The Impact Of Smoking On Preeclampsia/Eclampsia: Are There Age And Racial Differences?, Jen Jen Chang, Jerome F. Strauss Iii, Jon P. Deshazo, Fidelma B. Rigby, David P. Chelmow, George A. Macones

Open Access Publications

No abstract provided.


Extensive Error In The Number Of Genes Inferred From Draft Genome Assemblies, James F. Denton, Jose Lugo-Martinez, Abraham E. Tucker, Daniel R. Schrider, Wesley C. Warren, Matthew W. Hahn Jan 2014

Extensive Error In The Number Of Genes Inferred From Draft Genome Assemblies, James F. Denton, Jose Lugo-Martinez, Abraham E. Tucker, Daniel R. Schrider, Wesley C. Warren, Matthew W. Hahn

Open Access Publications

No abstract provided.


Pathogen Reduction In Human Plasma Using An Ultrashort Pulsed Laser, Shaw-Wei D. Tsen, David H. Kingsley, Karen Kibler, Bert Jacobs, Sara Sizemore, Sara M. Vaiana, Jeanne Anderson, Kong-Thon Tsen, Samuel Achilefu Jan 2014

Pathogen Reduction In Human Plasma Using An Ultrashort Pulsed Laser, Shaw-Wei D. Tsen, David H. Kingsley, Karen Kibler, Bert Jacobs, Sara Sizemore, Sara M. Vaiana, Jeanne Anderson, Kong-Thon Tsen, Samuel Achilefu

Open Access Publications

No abstract provided.


A Rare Sequence Variant In Intron 1 Of Thap1 Is Associated With Primary Dystonia, Joel S. Perlmutter, Brad A. Racette, Randal C. Paniello, Et Al Jan 2014

A Rare Sequence Variant In Intron 1 Of Thap1 Is Associated With Primary Dystonia, Joel S. Perlmutter, Brad A. Racette, Randal C. Paniello, Et Al

Open Access Publications

No abstract provided.


Glycosylation Variants Of A Β-Glucosidase Secreted By A Taiwanese Fungus, Chaetomella Raphigera, Exhibit Variant-Specific Catalytic And Biochemical Properties, Aki Yoneda, Hsion-Wen David Kuo, Mayumi Ishihara, Parastoo Azadi, Su-May Yu, Tuan-Hua David Ho Jan 2014

Glycosylation Variants Of A Β-Glucosidase Secreted By A Taiwanese Fungus, Chaetomella Raphigera, Exhibit Variant-Specific Catalytic And Biochemical Properties, Aki Yoneda, Hsion-Wen David Kuo, Mayumi Ishihara, Parastoo Azadi, Su-May Yu, Tuan-Hua David Ho

Open Access Publications

No abstract provided.


Α2Β1 Integrin, Gpvi Receptor, And Common Fcrγ Chain On Mouse Platelets Mediate Distinct Responses To Collagen In Models Of Thrombosis, Robin J. Marjoram, Zhengzhi Li, Li He, Douglas M. Tollefsen, Thomas J. Kunicki, S. Kent Dickeson, Samuel A. Santoro, Mary M. Zutter Jan 2014

Α2Β1 Integrin, Gpvi Receptor, And Common Fcrγ Chain On Mouse Platelets Mediate Distinct Responses To Collagen In Models Of Thrombosis, Robin J. Marjoram, Zhengzhi Li, Li He, Douglas M. Tollefsen, Thomas J. Kunicki, S. Kent Dickeson, Samuel A. Santoro, Mary M. Zutter

Open Access Publications

No abstract provided.


Joint Testing Of Genotypic And Gene-Environment Interaction Identified Novel Association For Bmp4 With Non-Syndromic Cl/P In An Asian Population Using Data From An International Cleft Consortium, Qianqian Chen, Hong Wang, Holger Schwender, Tianxiao Zhang, Jacqueline B. Hetmanski, Yah-Huei Wu Chou, Xiaoqian Ye, Vincent Yeow, Samuel S. Chong, Bo Zhang, Ethylin Wang Jabs, Margaret M. Parker, Alan F. Scott, Terri H. Beaty Jan 2014

Joint Testing Of Genotypic And Gene-Environment Interaction Identified Novel Association For Bmp4 With Non-Syndromic Cl/P In An Asian Population Using Data From An International Cleft Consortium, Qianqian Chen, Hong Wang, Holger Schwender, Tianxiao Zhang, Jacqueline B. Hetmanski, Yah-Huei Wu Chou, Xiaoqian Ye, Vincent Yeow, Samuel S. Chong, Bo Zhang, Ethylin Wang Jabs, Margaret M. Parker, Alan F. Scott, Terri H. Beaty

Open Access Publications

No abstract provided.


Optimal Body Weight For Health And Longevity: Bridging Basic, Clinical, And Population Research, Luigi Fontana, Frank B. Hu Jan 2014

Optimal Body Weight For Health And Longevity: Bridging Basic, Clinical, And Population Research, Luigi Fontana, Frank B. Hu

Open Access Publications

No abstract provided.


Dendritic Cells In Dengue Virus Infection: Targets Of Virus Replication And Mediators Of Immunity, Michael A. Schmid, Michael S. Diamond, Eva Harris Jan 2014

Dendritic Cells In Dengue Virus Infection: Targets Of Virus Replication And Mediators Of Immunity, Michael A. Schmid, Michael S. Diamond, Eva Harris

Open Access Publications

No abstract provided.


Antisense Reduction Of The Protein Tau Attenuates Neuronal Hyper-Excitability And Permits Clearance Of Intraneuronal Tau Accumulations In Vivo, Sarah Devos Jan 2014

Antisense Reduction Of The Protein Tau Attenuates Neuronal Hyper-Excitability And Permits Clearance Of Intraneuronal Tau Accumulations In Vivo, Sarah Devos

Open Access Publications

No abstract provided.


Targeting An Ikbke Cytokine Network Impairs Triple-Negative Breast Cancer Growth, Thanh U. Barbie, Shunqiang Li, Xiuli Zhang, John Herndon, Timothy Fleming, Matthew J. Ellis, William E. Gillanders, Et Al Jan 2014

Targeting An Ikbke Cytokine Network Impairs Triple-Negative Breast Cancer Growth, Thanh U. Barbie, Shunqiang Li, Xiuli Zhang, John Herndon, Timothy Fleming, Matthew J. Ellis, William E. Gillanders, Et Al

Open Access Publications

No abstract provided.


Phylogenomics And The Dynamic Genome Evolution Of The Genus Streptococcus, Vincent P. Richards, Sara R. Palmer, Paulina D. Pavinski Bitar, Xiang Qin, George M. Weinstock, Sarah K. Highlander, Christopher D. Town, Robert A. Burne, Michael J. Stanhope Jan 2014

Phylogenomics And The Dynamic Genome Evolution Of The Genus Streptococcus, Vincent P. Richards, Sara R. Palmer, Paulina D. Pavinski Bitar, Xiang Qin, George M. Weinstock, Sarah K. Highlander, Christopher D. Town, Robert A. Burne, Michael J. Stanhope

Open Access Publications

No abstract provided.


Bkca Channel Inhibitor Modulates The Tumorigenic Ability Of Hormone-Independent Breast Cancer Cells Via The Wnt Pathway, Brandon M. Schickling, Sarah K. England, Nukhet Aykin-Burns, Lyse A. Norian, Kimberly K. Leslie, Victoria P. Frieden-Korovkina Jan 2014

Bkca Channel Inhibitor Modulates The Tumorigenic Ability Of Hormone-Independent Breast Cancer Cells Via The Wnt Pathway, Brandon M. Schickling, Sarah K. England, Nukhet Aykin-Burns, Lyse A. Norian, Kimberly K. Leslie, Victoria P. Frieden-Korovkina

Open Access Publications

No abstract provided.


Psychiatric Correlates Of Snuff And Chewing Tobacco Use, Qiang Fu, Michael G. Vaughn, Li-Tzy Wu, Andrew C. Heath Jan 2014

Psychiatric Correlates Of Snuff And Chewing Tobacco Use, Qiang Fu, Michael G. Vaughn, Li-Tzy Wu, Andrew C. Heath

Open Access Publications

No abstract provided.


Genetic Analysis Of Circadian Responses To Low Frequency Electromagnetic Fields In Drosophila Melanogaster, Giorgio Fedele, Mathew D. Edwards, Supriya Bhutani, John M. Hares, Manuel Murbach, Edward W. Green, Stephane Dissel, Michael H. Hasting, Ezio Rosato, Charalambos P. Kyriacou Jan 2014

Genetic Analysis Of Circadian Responses To Low Frequency Electromagnetic Fields In Drosophila Melanogaster, Giorgio Fedele, Mathew D. Edwards, Supriya Bhutani, John M. Hares, Manuel Murbach, Edward W. Green, Stephane Dissel, Michael H. Hasting, Ezio Rosato, Charalambos P. Kyriacou

Open Access Publications

No abstract provided.


A Clathrin Coat Assembly Role For The Muniscin Protein Central Linker Revealed By Talen-Mediated Gene Editing, Perunthottathu K. Umasankar, Li Ma, James R. Thieman, Anupma Jha, Balraj Doray, Simon C. Watkins, Linton M. Traub Jan 2014

A Clathrin Coat Assembly Role For The Muniscin Protein Central Linker Revealed By Talen-Mediated Gene Editing, Perunthottathu K. Umasankar, Li Ma, James R. Thieman, Anupma Jha, Balraj Doray, Simon C. Watkins, Linton M. Traub

Open Access Publications

No abstract provided.


Structure Of Cellular Escrt-Iii Spirals And Their Relationship To Hiv Budding, Anil G. Cashikar, Soomin Shim, Robyn Roth, Michael R. Maldazys, John E. Heuser, Phyllis I. Hanson Jan 2014

Structure Of Cellular Escrt-Iii Spirals And Their Relationship To Hiv Budding, Anil G. Cashikar, Soomin Shim, Robyn Roth, Michael R. Maldazys, John E. Heuser, Phyllis I. Hanson

Open Access Publications

No abstract provided.


Nextgen Sequencing Reveals Short Double Crossovers Contribute Disproportionately To Genetic Diversity In Toxoplasma Gondii, Asis Khan, Jahangheer S. Shaik, Michael Behnke, Qiuling Wang, Jitender P. Dubey, Hernan A. Lorenzi, James W. Ajioka, Benjamin M. Rosenthal, L. David Sibley Jan 2014

Nextgen Sequencing Reveals Short Double Crossovers Contribute Disproportionately To Genetic Diversity In Toxoplasma Gondii, Asis Khan, Jahangheer S. Shaik, Michael Behnke, Qiuling Wang, Jitender P. Dubey, Hernan A. Lorenzi, James W. Ajioka, Benjamin M. Rosenthal, L. David Sibley

Open Access Publications

No abstract provided.


Invariance And Plasticity In The Drosophila Melanogaster Metabolomic Network In Response To Temperature, Ramkumar Hariharan, Jessica M. Hoffman, Ariel S. Thomas, Quinlyn A. Soltow, Dean P. Jones, Daniel E.L. Promislow Jan 2014

Invariance And Plasticity In The Drosophila Melanogaster Metabolomic Network In Response To Temperature, Ramkumar Hariharan, Jessica M. Hoffman, Ariel S. Thomas, Quinlyn A. Soltow, Dean P. Jones, Daniel E.L. Promislow

Open Access Publications

No abstract provided.


Comparative Analyses Of Proteins From Haemophilus Influenzae Biofilm And Planktonic Populations Using Metabolic Labeling And Mass Spectrometry, Deborah Mb Post, Jason M. Held, Margaret R. Ketterer, Nancy J. Phillips, Alexandria Sahu, Michael A. Apicella, Bradford W. Gibson Jan 2014

Comparative Analyses Of Proteins From Haemophilus Influenzae Biofilm And Planktonic Populations Using Metabolic Labeling And Mass Spectrometry, Deborah Mb Post, Jason M. Held, Margaret R. Ketterer, Nancy J. Phillips, Alexandria Sahu, Michael A. Apicella, Bradford W. Gibson

Open Access Publications

No abstract provided.


Conserved Syntenic Clusters Of Protein Coding Genes Are Missing In Birds, Peter V. Lovell, Morgan Wirthlin, Larry Wilhelm, Patrick Minx, Nathan H. Lazar, Lucia Carbone, Wesley C. Warren, Claudio V. Mello Jan 2014

Conserved Syntenic Clusters Of Protein Coding Genes Are Missing In Birds, Peter V. Lovell, Morgan Wirthlin, Larry Wilhelm, Patrick Minx, Nathan H. Lazar, Lucia Carbone, Wesley C. Warren, Claudio V. Mello

Open Access Publications

No abstract provided.


Risk-Stratified Patients With Resectable Soft Tissue Sarcoma Benefit From Epirubicin-Based Adjuvant Chemotherapy, Aaron D. Schenone, Jingqin Luo, Luke Montgomery, Daniel Morgensztern, Douglas R. Adkins, Brian A. Van Tine Jan 2014

Risk-Stratified Patients With Resectable Soft Tissue Sarcoma Benefit From Epirubicin-Based Adjuvant Chemotherapy, Aaron D. Schenone, Jingqin Luo, Luke Montgomery, Daniel Morgensztern, Douglas R. Adkins, Brian A. Van Tine

Open Access Publications

No abstract provided.


Significance Of The D-Serine-Deaminase And D-Serine Metabolism Of Staphylococcus Saprophyticus For Virulence, Miriam Korte-Berwanger, Turkan Sakinc, Kimberly Kline, Hailyn V. Nielsen, Scott Hultgren, Soren G. Gatermann Dec 2013

Significance Of The D-Serine-Deaminase And D-Serine Metabolism Of Staphylococcus Saprophyticus For Virulence, Miriam Korte-Berwanger, Turkan Sakinc, Kimberly Kline, Hailyn V. Nielsen, Scott Hultgren, Soren G. Gatermann

Open Access Publications

No abstract provided.


Neuronal Clearance Of Amyloid-Β By Endocytic Receptor Lrp1, Takahisa Kanekiyo, John R. Cirrito, Chia-Chen Liu, Mitsuru Shinohara, Jie Li, Dorothy R. Schuler, Motoko Shinohara, David M. Holtzman, Guojun Bu Dec 2013

Neuronal Clearance Of Amyloid-Β By Endocytic Receptor Lrp1, Takahisa Kanekiyo, John R. Cirrito, Chia-Chen Liu, Mitsuru Shinohara, Jie Li, Dorothy R. Schuler, Motoko Shinohara, David M. Holtzman, Guojun Bu

Open Access Publications

Alzheimer's disease (AD) is the most prevalent form of dementia in the elderly population. Accumulation, aggregation, and deposition of amyloid-β (Aβ) peptides generated through proteolytic cleavage of amyloid precursor protein (APP) are likely initiating events in the pathogenesis of AD. While Aβ production is accelerated in familial AD, increasing evidence indicates that impaired clearance of Aβ is responsible for late-onset AD. Because Aβ is mainly generated in neurons, these cells are predicted to have the highest risk of encountering Aβ among all cell types in the brain. However, it is still unclear whether they are also involved in Aβ clearance. …


Alpha Interferon Restricts Human T-Lymphotropic Virus Type 1 And 2 De Novo Infection Through Pkr Activation, Anne Cachat, Sebastien Alain Chevalier, Sandrine Alais, Nga Ling Ko, Lee Ratner, Chloe Journo, Helene Dutartre, Renaud Mahleux Dec 2013

Alpha Interferon Restricts Human T-Lymphotropic Virus Type 1 And 2 De Novo Infection Through Pkr Activation, Anne Cachat, Sebastien Alain Chevalier, Sandrine Alais, Nga Ling Ko, Lee Ratner, Chloe Journo, Helene Dutartre, Renaud Mahleux

Open Access Publications

No abstract provided.


Dietary Protein Restriction Inhibits Tumor Growth In Human Xenograft Models Of Prostate And Breast Cancer, Luigi Fontana, Remi M. Adelaiye, Antonella L. Rastelli, Kiersten Marie Miles, Eric Ciamporcero, Valter D. Longo, Holly Nguyen, Robert Vessella, Roberto Pili Dec 2013

Dietary Protein Restriction Inhibits Tumor Growth In Human Xenograft Models Of Prostate And Breast Cancer, Luigi Fontana, Remi M. Adelaiye, Antonella L. Rastelli, Kiersten Marie Miles, Eric Ciamporcero, Valter D. Longo, Holly Nguyen, Robert Vessella, Roberto Pili

Open Access Publications

No abstract provided.


Loss Of The Spectraplakin Short Stop Activates The Dlk Injury Response Pathway In Drosophila, Vera Valakh, Lauren J. Walker, James B. Skeath, Aaron Diantonio Nov 2013

Loss Of The Spectraplakin Short Stop Activates The Dlk Injury Response Pathway In Drosophila, Vera Valakh, Lauren J. Walker, James B. Skeath, Aaron Diantonio

Open Access Publications

No abstract provided.


The Choroid Plexus And Cerebrospinal Fluid: Emerging Roles In Development, Disease, And Therapy, Maria K. Lehtinen, Christopher S. Bjornsson, Susan M. Dymecki, Richard J. Gilbertson, David M. Holtzman, Edwin S. Monuki Nov 2013

The Choroid Plexus And Cerebrospinal Fluid: Emerging Roles In Development, Disease, And Therapy, Maria K. Lehtinen, Christopher S. Bjornsson, Susan M. Dymecki, Richard J. Gilbertson, David M. Holtzman, Edwin S. Monuki

Open Access Publications

No abstract provided.