Digital Commons Network^™

Commonwealth Times 2006-09-11

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-09-07

Commonwealth Times, 1969-

No abstract provided.

Shafer Court Connections (2006-09)

Shafer Court Connections, 1994-2010

For alumni of the Academic Campus of Virginia Commonwealth University.

Commonwealth Times 2006-08-31

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-08-28

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-08-24

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-06-19

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-04-24

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-04-20

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-04-13

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-04-10

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-03-27

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-03-20

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-03-09

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-03-06

Commonwealth Times, 1969-

No abstract provided.

Shafer Court Connections (2006-03)

Shafer Court Connections, 1994-2010

For alumni of the Academic Campus of Virginia Commonwealth University.

Commonwealth Times 2006-02-27

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-02-23

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-02-16

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2006-02-09

Commonwealth Times, 1969-

No abstract provided.

Orientational Correlations In Liquid Acetone And Dimethyl Sulfoxide: A Comparative Study, Sylvia E. Mclain, Alan K. Soper, Alenka Luzar

Chemistry Publications

The structure of acetone and dimethyl sulfoxide in the liquid state is investigated using a combination of neutron diffractionmeasurements and empirical potential structure refinement (EPSR) modeling. By extracting the orientational correlations from the EPSR model, the alignment of dipoles in both fluids is identified. At short distances the dipoles or neighboring molecules are found to be in antiparallel configurations, but further out the molecules tend to be aligned predominately as head to tail in the manner of dipolar ordering. The distribution of these orientations in space around a central molecule is strongly influenced by the underlying symmetry of the central …

Glucose Modulates [Ca2+]I Oscillations In Pancreatic Islets Via Ionic And Glycolytic Mechanisms, Craig S. Nunemaker, Richard Bertram, Arthur Sherman, Krasimira Tsaneva-Atanasova, Camille R. Daniel, Leslie S. Satin

Pharmacology and Toxicology Publications

Abstract

Pancreatic islets of Langerhans display complex intracellular calcium changes in response to glucose that include fast (seconds), slow (∼5 min), and mixed fast/slow oscillations; the slow and mixed oscillations are likely responsible for the pulses of plasma insulin observed in vivo. To better understand the mechanisms underlying these diverse patterns, we systematically analyzed the effects of glucose on period, amplitude, and plateau fraction (the fraction of time spent in the active phase) of the various regimes of calcium oscillations. We found that in both fast and slow islets, increasing glucose had limited effects on amplitude and period, but increased …

Structure And Bonding Of Au5m (M=Na, Mg, Al, Si, P, And S) Clusters, Chiranjib Majumder, Anil K. Kandalam, Puru Jena

Physics Publications

The atomic and electronic structure of Au5M (M=Na, Mg, Al, Si, P, S, and Au) clusters have been investigated using generalized gradient approximation to the density functional theory. Depending on the nature of interaction with different impurity elements a structural transition from planar to nonplanar configuration has been observed in Au5M. With the exception of S, impurities with p electrons (Al, Si, P) yield nonplanar geometries of Au5M clusters, while those with selectrons (Na, Mg) yield planar geometries. The properties of Au5Scluster are anomalous: The cluster not only has a planar geometry, but also is chemically most stable with the …

Effect Of Au Coating On The Magnetic And Structural Properties Of Fe Nanoclusters For Use In Biomedical Applications: A Density-Functional Theory Study, Q. Sun, A. K. Kandalam, Q. Wang, Puru Jena, Y. Kawazoe, M. Marquez

Physics Publications

In this paper, we report the first systematic theoretical study of gold-coated iron nanoclusters, aiming at understanding the magnetic properties of this core-shell structure used in biomedical applications. The calculations based on density-functional theory focus on the effect of gold coating on the magnetic and structural properties of iron clusters of various sizes, and the reaction of the bare and coated iron clusters with oxygen. Our results show that the magnetic moment of iron nanocore with gold coating is still significantly higher than that in bulk Fe; the coupling between Fe atoms remained ferromagnetic and is insensitive to the thickness …

Structure And Stability Of Co-N(Pyridine)(M)(-) Clusters: Absence Of Metal Inserted Structures, B. Douglas Edmonds, A. K. Kandalam, S. N. Khanna, X. Li, A. Grubisic, I. Khanna, K. H. Bowen

Physics Publications

A synergistic approach combining the experimental photoelectron spectroscopy and theoretical electronic structure studies is used to probe the geometrical structure and the spin magnetic moment of Con(pyridine)−m clusters. It is predicted that the ground state of Co(pyridine)− is a structure where the Co atom is inserted in a CH bond. However, the insertion is marked by a barrier of 0.33eV that is not overcome under the existing experimental conditions resulting in the formation of a structure where Co occupies a site above the pyridine plane. For Co2(pyridine)−, a ground-state structure is predicted in which the Co2 diametric moiety is inserted …

Gold As Hydrogen: Structural And Electronic Properties And Chemical Bonding In Si3au3+/0/- And Comparisons To Si3h3+/0/-, Boggavarapu Kiran, Xi Li, Hua-Jin Zhai, Lai-Sheng Wang

Physics Publications

A single Au atom has been shown to behave like H in its bonding to Si in several mono- and disilicon gold clusters. In the current work, we investigate the Au∕H analogy in trisilicon gold clusters, Si3Au+∕0∕−3. Photoelectron spectroscopy and density functional calculations are combined to examine the geometric and electronic structure of Si3Au−3. We find that there are three isomers competing for the ground state of Si3Au−3 as is the case for Si3H−3. Extensive structural searches show that the potential energy surfaces of the trisilicon gold clusters (Si3Au−3, Si3Au3, and Si3Au+3) are similar to those of the corresponding silicon …

Elderfriends: Relieving Loneliness Among Elders, Kiersten Seeger Ware, Sarah Coble

Case Studies from Age in Action

Educational Objectives

1. To discuss social isolation among older adults.

2. To promote awareness of the ElderFriends program, an intervention newly established in greater Richmond

3. To seek friendly visitors for the ElderFriends program.

Brain Health: Mending The Mind After Age 50, Susan Hardwicke

Case Studies from Age in Action

Educational Objectives

1. Increase understanding of brain function and its potential to improve with age.

2. Describe an application of neuroscience, cognitive training, and nutrition for solving a problem associated with aging.

3. Evaluate neural plasticity with aging.

Nectin-2-Mediated Entry Of A Syncytial Strain Of Herpes Simplex Virus Via Ph-Independent Fusion With The Plasma Membrane Of Chinese Hamster Ovary Cells, Mark G. Delboy, Jennifer L. Patterson, Aimee M. Hollander, Anthony V. Nicola

Microbiology and Immunology Publications

Background

Herpes simplex virus (HSV) can utilize multiple pathways to enter host cells. The factors that determine which route is taken are not clear. Chinese hamster ovary (CHO) cells that express glycoprotein D (gD)-binding receptors are model cells that support a pH-dependent, endocytic entry pathway for all HSV strains tested to date. Fusion-from-without (FFWO) is the induction of target cell fusion by addition of intact virions to cell monolayers in the absence of viral protein expression. The receptor requirements for HSV-induced FFWO are not known. We used the syncytial HSV-1 strain ANG path as a tool to evaluate the complex …

Surgical Infection Society Guidelines For Vaccination After Traumatic Injury, Thomas R. Howdieshell, Daithi Heffernan, Joseph T. Dipiro

Publications from the Office of the Dean

Background: Recommendations for vaccination of injured patients against infection are evolving. Newly-recognized infections, safety considerations, changing epidemiology, and redefinition of patient groups at risk are factors that may influence vaccine development priorities and recommendations for immunization. However, recommendations must often be formulated based on incomplete data, forcing reliance on expert opinion to address some crucial questions. These guidelines provide evidence-based recommendations for the prevention or treatment of infectious morbidity and mortality after traumatic injury, such as soft tissue wounds, human or animal bites, or after splenectomy.

Methods: A panel of experts conducted a thorough review of published literature, …