Digital Commons Network^™

Commonwealth Times 2009-02-05

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2009-02-02

Commonwealth Times, 1969-

No abstract provided.

Responding To The Plague Years: Aids Theatre In The 1980s, Jason Campbell

Theses and Dissertations

Acquired Immune Deficiency Syndrome (AIDS) was first discovered in 1981 and consequently changed United States history. Initially, it affected the gay community, and the United States Government did not actively combat the spread of the disease for the first four years of the epidemic. In response to a need for education, the theatre community took it upon itself to raise awareness about the disease. Artists such as Robert Chesley and Larry Kramer created pieces of theatre that helped society deal with AIDS. This thesis explores the AIDS theatre canon while focusing on two major works: Robert Chesley’s Night Sweat: A …

Commonwealth Times 2009-01-29

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2009-01-26

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2009-01-22

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2009-01-15

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2009-01-12

Commonwealth Times, 1969-

No abstract provided.

The Developmental Effect Of Human Embryoid Bodies (Heb) Under Dynamic Culturing Conditions Using A Perfusion Based Slow Turning Lateral Vessel (Stlv) Bioreactor, Claiborne Collier

Theses and Dissertations

Human embryonic stem cells (hESCs) can provide a unique approach for novel tissue engineering applications. Previous groups have shown that hESCs can differentiate into specialized cell types through the generation of human embryoid bodies (hEBs). These multi-cellular constructs are then subjected to suspension culture for several weeks. Traditional hESC differentiation techniques have yielded non-homogeneous EBs derived in standard static cultures providing an inefficient platform for cellular viability and embryonic modeling. Here, our study aimed at systematically comparing the formation, growth, and differentiation capabilities of hESC-derived hEBs in dynamic and static suspension cultures. We used a continuous flow perfusion slow turning …

Virginia Commonwealth University Graduate And Professional Programs Bulletin [2009], Virginia Commonwealth University

VCU Bulletins

Graduate and professional programs bulletin for Virginia Commonwealth University for the academic year 2009-2010. It includes information on academic regulations, degree requirements, course offerings, faculty, academic calendar, and tuition and expenses for graduate and professional programs.

The Literary And Political Activity Of Manuscript Verse Collectors, Joshua Eckhardt

English Publications

Chapter One of Manuscript verse collectors and the politics of anti-courtly love poetry, by Joshua Eckhardt.

The book analyzes the distinctive contribution to literary history of early-seventeenth-century hand-written English poetry anthologies. Compiled by manuscript verse collectors, these anthologies preserved a number of pieces by major authors of the English Renaissance, yet they tended to surround them with unprintable verses on sex and politics.

Multiple Splice Defects In Abca1 Cause Low Hdl-C In A Family With Hypoalphalipoproteinemia And Premature Coronary Disease, Jeffrey Rhyne, Myrna M. Mantaring, David F. Gardner, Michael Miller

Internal Medicine Publications

Background Mutations at splice junctions causing exon skipping are uncommon compared to exonic mutations, and two intronic mutations causing an aberrant phenotype have rarely been reported. Despite the high number of functional ABCA1 mutations reported to date, splice variants have been reported infrequently. We screened DNA from a 41 year-old male with low HDL-C (12 mg/dL [0.31 mmol/L]) and a family history of premature coronary heart disease (CHD) using polymerase chain reaction single-strand conformation polymorphism (SSCP) analysis.

Methods Family members with low levels of HDL-C (n = 6) were screened by SSCP for mutations in ABCA1. Samples with altered SSCP …

The Importance Of Saccular Function To Motor Development In Children With Hearing Impairments, Mary S. Shall

Physical Therapy Publications

Children with hearing deficits frequently have delayed motor development. The purpose of this study was to evaluate saccular function in children with hearing impairments using the Vestibular Evoked Myogenic Potential (VEMP). The impact of the saccular hypofunction on the timely maturation of normal balance strategies was examined using the Movement Assessment Battery for Children (Movement ABC). Thirty-three children with bilateral severe/profound hearing impairment between 4 and 7 years of age were recruited from a three-state area. Approximately half of the sample had one or bilateral cochlear implants, one used bilateral hearing aids, and the rest used no amplification. Parents reported …

Whole-Genome Resequencing Of Escherichia Coli K-12 Mg1655 Undergoing Short-Term Laboratory Evolution In Lactate Minimal Media Reveals Flexible Selection Of Adaptive Mutations, Tom M. Conrad, Andrew R. Royce, M. Kenyon Applebee, Christian L. Barrett, Bin Xie, Yuan Gao, Bernhard Ø. Palsson

Computer Science Publications

Background

Short-term laboratory evolution of bacteria followed by genomic sequencing provides insight into the mechanism of adaptive evolution, such as the number of mutations needed for adaptation, genotype-phenotype relationships, and the reproducibility of adaptive outcomes.

Results

In the present study, we describe the genome sequencing of 11 endpoints of Escherichia coli that underwent 60-day laboratory adaptive evolution under growth rate selection pressure in lactate minimal media. Two to eight mutations were identified per endpoint. Generally, each endpoint acquired mutations to different genes. The most notable exception was an 82 base-pair deletion in the rph-pyrE operon that appeared in …

Virginia Commonwealth University Commencement Program [2009], Virginia Commonwealth University

VCU Commencement Programs

No abstract provided.

Electronic Health, Hui Chen, Arnauld Nicogossian, Silas Olsson, Azhar Rafiq, Max E. Stachura, Mamoru Watanabe, Pamela Whitten, Yang Xiao

Human Simulation and Patient Safety Publications

This article has no abstract.

A Realistic Modeling Of Fluid Infiltration In Thin Fibrous Sheets, Sudhakar Jaganathan, Hooman Vahedi Tafreshi, Behnam Pourdeyhimi

Mechanical and Nuclear Engineering Publications

In this paper, a modeling study is presented to simulate the fluid infiltration in fibrous media. The Richards’ equation of two-phase flow in porous media is used here to model the fluid absorption in unsaturated/partially saturated fibrous thin sheets. The required consecutive equations, relative permeability, and capillary pressure as functions of medium’s saturation are obtained via fiber-level modeling and a long-column experiment, respectively. Our relative permeability calculations are based on solving the Stokes flow equations in partially saturated three-dimensional domains obtained by imaging the sheets’ microstructures. The Richards’ equation, together with the above consecutive correlations, is solved for fibrous media …

Staphylococcus Aureus Immunodominant Surface Antigen B Is A Cell-Surface Associated Nucleic Acid Binding Protein, Nicole M. Mackey-Lawrence, Denise E. Potter, Nuno Cerca, Kimberly K. Jefferson

Microbiology and Immunology Publications

Background

Staphylococcus aureus immunodominant surface antigen B (IsaB) elicits an immune response during septicemia and is generally classified as a virulence factor, but its biological function remains completely undefined. In an attempt to identify staphylococcal RNA-binding proteins, we designed an RNA Affinity Chromatography assay and subsequently isolated IsaB.

Results

Western analysis indicated that IsaB was both secreted and cell-surface associated. Gel Shift analysis confirmed the RNA binding activity but revealed that IsaB bound to any nucleic acid without sequence specificity. IsaB exhibited the highest affinity for double-stranded DNA followed by single-stranded DNA and RNA. Because extracellular DNA has been shown …

Virginia Commonwealth University Undergraduate Bulletin Courses [2009], Virginia Commonwealth University

VCU Bulletins

Listing of undergraduate courses for 2009-2010.

Virginia Commonwealth University Graduate And Professional Programs Bulletin Courses [2009], Virginia Commonwealth University

VCU Bulletins

Listing of professional and graduate courses for 2009-2010.

Developing Multicultural Intelligence Through The Work Of Kehinde Wiley, Melanie L. Buffington

Art Education Publications

Through a review of current events, contemporary ideas on multicultural education, and the art of Kehinde Wiley, this article argues that using the work of contemporary artists is one way to introduce pre-service teachers to the complex issues of multiculturalism, race, and culture in contemporary society. By learning about contemporary artists whose work overtly relates to race and culture, pre-service teachers may become more comfortable with the realities of the multicultural schools they encounter throughout their careers. Additionally, the article introduces portraiture methodology as a means of understanding interactions in university classrooms, especially as they relate to pre-service teacher education. …

Virginia Commonwealth University Fall Commencement Program [2009], Virginia Commonwealth University

VCU Commencement Programs

No abstract provided.

Virginia Commonwealth University Undergraduate Bulletin [2009], Virginia Commonwealth University

VCU Bulletins

Undergraduate bulletin for Virginia Commonwealth University for the academic year 2009-2010. It includes information on academic regulations, degree requirements, course offerings, faculty, academic calendar, and tuition and expenses for undergraduate programs.

Antimalarial Activity Of A Cis-Terpenone, Dc Ghislaine Mayer, Maimuna Bruce, Olga Kochurova, Jennifer K. Stewart, Qibing Zhou

Biology Publications

Background

Malaria is the third most prevalent cause of infectious disease in the world. Resistance of the parasite to classical drugs makes the discovery of new and effective drugs more urgent. The oxidized derivative of hydroxy-cis terpenone (OHCT) is a synthetic molecule that is not toxic to cultured human liver cells at concentrations as high as 60 μM and inhibits activity of cytochrome P450s that metabolize many drugs.

Methods

OHCT activity against chloroquine-sensitive and -resistant strains of Plasmodium falciparum, and aP. falciparum clone that is partially resistant to artemisinin was assayed in vitro.

Results

OHCT at nanomolar …

Vcu Volunteers, Grace E. Harris Leadership Institute, Virginia Commonwealth University, James Mays, Jeanne Mcneil, Lynn Pelco, Lisa Price-Stevens, Jamie Stillman, Lydia Zirkle

L. Douglas Wilder School of Government and Public Affairs Publications

VCU Volunteers follows VCU’s history of developing mutually partnerships with the community and is supported by VCU 2020 Theme 5- A model for community-university partnerships. VCU Volunteers will make VCU a better place to work by fostering a sense of belonging and pride in employees at all levels. The mission of VCU Volunteers is to build a collaborative employee community through the shared experience of volunteering. An employee-driven steering committee will guide the activities of the program. This committee will be denied by an employee and will include representative’s membership for Human Resources – Work/Life Resources, Community Engagement, the VCU …

Mast Cell Regulation Of The Immune Response, John J. Ryan, Johanna K. Morales, Yves T. Falanga, Josephine Fa Fernando, Matthew R. Macey

Biology Publications

Mast cells are well known as principle effector cells of type I hypersensitivity responses. Beyond this role in allergic disease, these cells are now appreciated as playing an important role in many inflammatory conditions. This review summarizes the support for mast cell involvement in resisting bacterial infection, exacerbating autoimmunity and atherosclerosis, and promoting cancer progression. A commonality in these conditions is the ability of mast cells to elicit migration of many cell types, often through the production of inflammatory cytokines such as tumor necrosis factor. However, recent data also demonstrates that mast cells can suppress the immune response through interleukin-10 …

Endothelial Cells And Pulmonary Arterial Hypertension: Apoptosis, Proliferation, Interaction And Transdifferentiation, Seiichiro Sakao, Koichiro Tatsumi, Norbert F. Voelkel

VCU Health Publications

Severe pulmonary arterial hypertension, whether idiopathic or secondary, is characterized by structural alterations of microscopically small pulmonary arterioles. The vascular lesions in this group of pulmonary hypertensive diseases show actively proliferating endothelial cells without evidence of apoptosis. In this article, we review pathogenetic concepts of severe pulmonary arterial hypertension and explain the term "complex vascular lesion ", commonly named "plexiform lesion", with endothelial cell dysfunction, i.e., apoptosis, proliferation, interaction with smooth muscle cells and transdifferentiation.

Contributors

Ethnic Studies Review

Contributors to Ethnic Studies Review, Vol. 32, No. 1, Summer 2009.

Ethnic Studies Review

Ethnic Studies Review

No abstract provided.

Richard Carlyon: A Retrospective, Richard Carlyon

Anderson Gallery Art Exhibition Catalogues

Published in conjunction with the multisite exhibition Richard Carlyon: A Retrospective, which opened on September 11, 2009, and was organized by the Anderson Gallery, School of the Arts, Virginia Commonwealth University; Reynolds Gallery; 1708 Gallery; and Visual Arts Center of Richmond, all in Richmond, Va.