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Investigations On The Corrosion Resistance Of Metallic Bipolar Plates (Bpp) In Proton Exchange Membrane Fuel Cells (Pemfc) - Understanding Of The Effects Of Material, Coating And Manufacturing, Ender Dur Nov 2011

Investigations On The Corrosion Resistance Of Metallic Bipolar Plates (Bpp) In Proton Exchange Membrane Fuel Cells (Pemfc) - Understanding Of The Effects Of Material, Coating And Manufacturing, Ender Dur

Theses and Dissertations

Polymer Electrolyte Membrane Fuel Cell (PEMFC) systems are promising technology for contributing to meet the deficiency of world`s clean and sustainable energy requirements in the near future. Metallic bipolar plate (BPP) as one of the most significant components of PEMFC device accounts for the largest part of the fuel cell`s stack. Corrosion for metallic bipolar plates is a critical issue, which influences the performance and durability of PEMFC. Corrosion causes adverse impacts on the PEMFC`s performance jeopardizing commercialization. This research is aimed at determining the corrosion resistance of metallic BPPs, particularly stainless steels, used in PEMFC from different aspects. Material …


Assessing Budget Delays In The Commonwealth Of Virginia: A Cross State Analysis Of Political And Economic Factors, Emily Newton Nov 2011

Assessing Budget Delays In The Commonwealth Of Virginia: A Cross State Analysis Of Political And Economic Factors, Emily Newton

Theses and Dissertations

This paper assessed factors that delayed the passage of the annual budget bill specifically in Virginia and also in 13 structurally similar states including: Arizona, Connecticut, Indiana, Kentucky, Maine, Minnesota, Montana, New Hampshire, North Carolina, North Dakota, Texas, Washington, and Wyoming. Virginia was the core focus of this study, but the variables detailed below were also measured for all thirteen states in an effort to broaden the scope of the study, and determine which political and economic factors affected the budget passage rates in Virginia and the 13 other states. Political and economic explanations were tested to examine their relationship …


Commonwealth Times 2011-11-11 Nov 2011

Commonwealth Times 2011-11-11

Commonwealth Times, 1969-

No abstract provided.


Anaplasma Phagocytophilum Remodels Its Host Cell-Derived Vacuole Into A Protective Niche By Redecorating The Vacuolar Membrane With Select Rab Gtpases And Bacterial Proteins, Bernice Huang Nov 2011

Anaplasma Phagocytophilum Remodels Its Host Cell-Derived Vacuole Into A Protective Niche By Redecorating The Vacuolar Membrane With Select Rab Gtpases And Bacterial Proteins, Bernice Huang

Theses and Dissertations

Anaplasma phagocytophilum is an obligate intracellular bacterium that infects neutrophils to cause the emerging tick-transmitted disease, human granulocytic anaplasmosis (HGA). Following entry, the pathogen replicates within a host cell-derived vacuole that fails to mature along the endocytic pathway, does not acidify, and does not fuse with lysosomes. Selective fusogenicity is prototypical of many vacuole-adapted pathogens and has been attributed, at least in part, to pathogen modification of the vacuolar inclusion membrane and/or to selective recruitment or exclusion of host trafficking regulators. As a result, the A. phagocytophilum-occupied vacuolar membrane (AVM) provides a unique interface to study the host-pathogen interactions critical …


Childhood Maltreatment, Coping, And Coping Self-Efficacy Among Offenders, David Guion Nov 2011

Childhood Maltreatment, Coping, And Coping Self-Efficacy Among Offenders, David Guion

Theses and Dissertations

This study explored the relationship between childhood interpersonal trauma and coping self-efficacy, coping styles, and emotion regulation difficulties among male and female offenders in detention and diversion centers (N = 183). The coping-relapse model of recidivism posits that offenders’ coping ability plays a pivotal role in successful reentry (Zamble & Quinsey, 1997). Past research reveals that childhood maltreatment is associated with avoidant coping and emotion regulation difficulties, which could negatively impact reentry (e.g., Cloitre et al., 2009; Min, Farkas, Minnes, & Singer, 2007). The relationship between childhood maltreatment and coping self-efficacy has not been addressed. This study found that childhood …


[2011-11-10] Meeting Of The Board Of Visitors Of Virginia Commonwealth University, Virginia Commonwealth University. Board Of Visitors Nov 2011

[2011-11-10] Meeting Of The Board Of Visitors Of Virginia Commonwealth University, Virginia Commonwealth University. Board Of Visitors

VCU Board of Visitors Minutes

Official minutes of the VCU Board of Visitors and its Executive Committee.


An Examination Of Spiritual And Religious Coping And Well-Being And Their Impact On The Health-Related Quality Of Life For Patients With Mechanical Circulatory Support, Angela Hardy-Duncan Nov 2011

An Examination Of Spiritual And Religious Coping And Well-Being And Their Impact On The Health-Related Quality Of Life For Patients With Mechanical Circulatory Support, Angela Hardy-Duncan

Theses and Dissertations

Mechanical Circulatory Support (MCS) improves the health-related quality of life (HRQOL) for patients with end-stage heart failure (HF) (Friedrich & Bohm, 2007). Religious and spiritual practices positively influence health and well-being for cardiac patients (Ai, Park, Huang, Rodgers, & Tice, 2007; Blackhall, & Koenig, 1998). The purpose of this study was to examine the impact of spiritual well-being (SWB) and religious well-being (RWB) and coping styles and methods (CSM) on health related quality of life (HRQOL) of patients with MCS. This exploratory repeated measures study used Spearmans’ rho and Wilcoxons’ Signed Rank tests for correlation and comparison analyses. The study …


Computational Modeling And Simulation Study Of Dermal Wound Healing Proliferative Phase, Le Yang Nov 2011

Computational Modeling And Simulation Study Of Dermal Wound Healing Proliferative Phase, Le Yang

Theses and Dissertations

Dermal wound healing proliferative phase is a complicated physiological process in which many growth factors, cell types and matrix components participate. The process must be well coordinated to restore the structural and functional integrity of tissue injured. Many disorders interrupting healing process result in abnormal healing such as chronic wounds or excessive scarring. Mathematical modeling has been used to investigate many aspects of wound healing. Angiogenesis is pertinent for dermal wound healing since the cellular activities involved in tissue repair requires oxygen and nutrients to be delivered to the wound site. By using a hybrid agent-based model, we investigated the …


Commonwealth Times 2011-11-07 Nov 2011

Commonwealth Times 2011-11-07

Commonwealth Times, 1969-

No abstract provided.


Designing Allosteric Inhibitors Of Thrombin, Preetpal Sidhu Nov 2011

Designing Allosteric Inhibitors Of Thrombin, Preetpal Sidhu

Theses and Dissertations

Thrombin is a key enzyme of the coagulation cascade exhibiting important roles in both pro-coagulation and anti-coagulation processes. Most clinically used anticoagulant drugs, including polymeric heparin, warfarin, hirudin, argatroban and the recently approved dabigatran, aim to reduce thrombin activity. There are several binding domains on thrombin including the active site, anion-binding exosites I and II, and the sodium binding site. We hypothesized that thrombin may be better regulated through an allosteric process mediated by small molecules binding to either exosite I or II. An appropriately designed allosteric regulator that reduces the procoagulant signal in a finely tuned manner may maintain …


The Black Imprint Of Beauty, Jamesha Hairston Nov 2011

The Black Imprint Of Beauty, Jamesha Hairston

Theses and Dissertations

Artist Statement I am inspired by historical images that depict the struggle and triumph of African American women. As I think about myself as an artist, and a woman of color, I am reminded of the rich visual heritage of my culture. However, I am perplexed with the representations in the media of hair and skin care, and social issues of urban black women. The negative, idealized, and stereotypical images are not a true representation of each individual African American woman. My response to these images incorporates a study of self-characterization, personal experiences, racial distortions, and black female iconography. In …


Commonwealth Times 2011-11-03 Nov 2011

Commonwealth Times 2011-11-03

Commonwealth Times, 1969-

No abstract provided.


Ink (2011-11) Nov 2011

Ink (2011-11)

Ink, 2008-

The student-run features magazine covering the fashion, art, music and culture worlds at VCU and in Richmond. Published annually in print and updated regularly online.


Commonwealth Times 2011-10-31 Oct 2011

Commonwealth Times 2011-10-31

Commonwealth Times, 1969-

No abstract provided.


Commonwealth Times 2011-10-27 Oct 2011

Commonwealth Times 2011-10-27

Commonwealth Times, 1969-

No abstract provided.


Commonwealth Times 2011-10-24 Oct 2011

Commonwealth Times 2011-10-24

Commonwealth Times, 1969-

No abstract provided.


Indirect Screening: Enhancing Identification Of Illicit Drug Use During Pregnancy, Courtney Smith Oct 2011

Indirect Screening: Enhancing Identification Of Illicit Drug Use During Pregnancy, Courtney Smith

Theses and Dissertations

OBJECTIVE: Most drug use screening measures rely on and are validated against self-report. Fear of negative consequences often promotes denial of drug use. For pregnant women, social stigma and fear of legal consequences make underreporting of drug use even more likely. An indirect screener that could effectively identify pregnant women at risk for illicit drug use without reliance on disclosure would be clinically significant. The purpose of the current study was to develop and validate an indirect measure of prenatal drug use by comparing correlates of prenatal drug use to urinalysis results. METHOD: Pregnant women attending an OB appointment at …


Evaluation Of A Community Mental Health Center’S Assessment Clinic: Development Of A Novel Assessment Evaluation Tool, Cassidy C. Arnold Oct 2011

Evaluation Of A Community Mental Health Center’S Assessment Clinic: Development Of A Novel Assessment Evaluation Tool, Cassidy C. Arnold

Theses and Dissertations

High quality assessment services are the linchpin connecting youth with mental health problems to diagnosis-specific, evidence-based treatments. The effort to improve assessment services is in its early days and faces a number of substantial challenges. This study was an initial effort to address these challenges through the development of a standardized, multi-dimensional Assessment Instrument evaluation tool—the Strength of Measure (SoM)—based on operationally defined criteria supported by decades of psychometric research. The SoM and other criteria addressing assessment practices were piloted with data from 32 consecutive assessment reports from a community mental health center’s Assessment Clinic. Results indicate that none of …


Commonwealth Times 2011-10-10 Oct 2011

Commonwealth Times 2011-10-10

Commonwealth Times, 1969-

No abstract provided.


Commonwealth Times 2011-10-06 Oct 2011

Commonwealth Times 2011-10-06

Commonwealth Times, 1969-

No abstract provided.


The Development Of The Common Factor Therapist Competence Scale For Youth Psychotherapy, Ruth Brown Oct 2011

The Development Of The Common Factor Therapist Competence Scale For Youth Psychotherapy, Ruth Brown

Theses and Dissertations

In order to continue to improve the effectiveness of psychotherapy, researchers must identify key change processes. Unfortunately, there are disparate views in the field about the relative importance and potency of specific techniques versus relationship factors. Few measures have been developed to examine the relative contribution of these factors, particularly for child-focused treatment. The Common-Factor Therapist Competence Scale for Youth Psychotherapy (COMP-CF) was developed to address this deficit. For this study, 142 video-taped sessions of child CBT for anxiety were observed and rated by independent coders using the COMP-CF. The measure demonstrated good reliability and internal consistency. Significant between-therapist and …


Hospitals With Physican Ceos: An Institutional Theory Perspective, Jeremy Zoch Oct 2011

Hospitals With Physican Ceos: An Institutional Theory Perspective, Jeremy Zoch

Theses and Dissertations

ABSTRACT HOSPITALS WITH PHYSICIAN CEOS: AN INSTITUTIONAL THEORY PERSPECTIVE By: Jeremy S. Zoch, Ph.D. A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Health Related Sciences at Virginia Commonwealth University. Virginia Commonwealth University, 2011 Major Director: Kenneth R. White, Ph.D. Professor Department of Health Administration The complexities of the healthcare industry at the beginning of the 21st century continue to challenge hospitals to optimize their operations. A key leadership position in the overall success of a hospital is the role of the Chief Executive Officer. The purpose of this study was to …


Commonwealth Times 2011-10-03 Oct 2011

Commonwealth Times 2011-10-03

Commonwealth Times, 1969-

No abstract provided.


The Characterization Of The Anterograde And Retrograde Consequences Of Traumatic Axonal Injury In A Mouse Model Of Diffuse Brain Injury, John E. Greer Sep 2011

The Characterization Of The Anterograde And Retrograde Consequences Of Traumatic Axonal Injury In A Mouse Model Of Diffuse Brain Injury, John E. Greer

Theses and Dissertations

Traumatic axonal injury (TAI) is a consistent feature of (TBI) and is responsible for much of its associated morbidity. TAI is now recognized to result from progressive/secondary axonal injury, though much remains unknown in regards to the pathobiology and the long-term consequences of axonal injury. TAI has been described in the perisomatic domain, located within the neocortex following mild TBI, and within this domain has been linked to neuronal recovery, not neuronal cell death in the acute setting. Due to technical limitations, our understanding of the long-term fate of this neuronal population and the mechanisms responsible for permitting neuronal survival, …


Commonwealth Times 2011-09-29 Sep 2011

Commonwealth Times 2011-09-29

Commonwealth Times, 1969-

No abstract provided.


Characterization Of Cyclic-Di-Gmp Signaling With The Lyme Spirochete, Borrelia Burgdorferi, Jessica Kostick Sep 2011

Characterization Of Cyclic-Di-Gmp Signaling With The Lyme Spirochete, Borrelia Burgdorferi, Jessica Kostick

Theses and Dissertations

Lyme disease is a tick-borne infection caused by Borrelia burgdorferi, B. garinii, and B. afzelii. These spirochetes experience environmental fluctuations as they are passed between mammalian and Ixodes tick hosts throughout their enzootic cycle. Recent studies have suggested cyclic diguanylate (c-di-GMP), a ubiquitous secondary messenger, is a key modulator of B. burgdorferi adaptive responses and may play a significant role in cycle progression. In this study, we examined the impact of the sole diguanylate cyclase (Rrp1), c-di-GMP binding proteins (PlzA and PlzB), and HD-GYP-containing phosphodiesterase (PdeB) in disease establishment of both murine and Ixodes tick systems. Strains harboring targeted gene …


The Use Of Targeted Charge-Reversal Nanoparticles (Tcrns) To Investigate Nuclear Delivery Of Fluorescent Agents To Cancer Cells: Implications For Novel Prostate And Breast Cancer Therapy, Mario Dance Sep 2011

The Use Of Targeted Charge-Reversal Nanoparticles (Tcrns) To Investigate Nuclear Delivery Of Fluorescent Agents To Cancer Cells: Implications For Novel Prostate And Breast Cancer Therapy, Mario Dance

Theses and Dissertations

Nanotechnology has recently emerged as a strong contributor toward research efforts to develop targeted systems of drug delivery in cancer therapy. Our work investigates the therapeutic potential of Targeted Charge-Reversal Nanoparticles (TCRNs), a novel nanoparticle with in vitro evidence of nuclear drug delivery. Using M12 prostate cancer cells, MDA-MB-231 breast cancer cells, and modified derivatives of these cell lines, we investigated the ability of Folic Acid-tagged TCRNs to deliver Nile Red and Dimethyl Indole Redfluorescent (DiR) fluorescent dyes to the nucleus of cells using confocal microscopy and in vivo biphontonic imaging using Xenogen® Technology. Confocal imaging with the SCP28 derivative …


Composition Of Suspended And Benthic Particulate Matter In The Tidal Freshwater James River, Anne Schlegel Sep 2011

Composition Of Suspended And Benthic Particulate Matter In The Tidal Freshwater James River, Anne Schlegel

Theses and Dissertations

Investigating linkages between the compositions of suspended (seston) and benthic particulate matter is important to the understanding of organic matter (OM) cycling and nutrient retention in aquatic systems. We compared the quantity and quality of the truly suspended (TS) and settleable (SB) fractions of seston as well as benthic particulate matter in the tidal freshwater James River, Virginia. The mass of seston and OM was consistently higher in the TS fraction compared to the SB fraction. OM was preferentially retained in the TS fraction relative to seston. The proportional contribution of OM constituents (chlorophyll a, particulate organic carbon and nitrogen) …


Commonwealth Times 2011-09-19 Sep 2011

Commonwealth Times 2011-09-19

Commonwealth Times, 1969-

No abstract provided.


The Regulation Of Tonb-Dependent Transporters In Neisseria Gnorrhoeae, Aimee Hollander Sep 2011

The Regulation Of Tonb-Dependent Transporters In Neisseria Gnorrhoeae, Aimee Hollander

Theses and Dissertations

Neisseria gonorrhoeae is an obligate human pathogen that causes the common sexually- transmitted infection, gonorrhea. Gonococcal infections cause significant morbidity, particularly among women, as the organism ascends to the upper reproductive tract, resulting in pelvic inflammatory disease, ectopic pregnancy and infertility. Antibiotic resistance rates have risen dramatically, leading to severe restriction of treatment options for gonococcal disease. Gonococcal infections do not elicit protective immunity nor is there an effective vaccine to prevent the disease. Thus, further characterization of expression, function and regulation of surface antigens could lead to better treatment and prevention modalities in the future. N. gonorrhoeae express a …