Digital Commons Network^™

Treatment Of Inborn Errors Of Urea Synthesis — Activation Of Alternative Pathways Of Waste Nitrogen Synthesis And Excretion, Mark L. Batshaw , M.D., Saul Brusilow , M.D., Lewis Waber , Ph.D., M.D., Wim Blom , Ph.D., Ann Mari Brubakk , M.D., Barbara K. Burton , M.D., Howard M. Cann , M.D., Douglas Kerr , M.D., Peter Mamunes , M.D., Reuben Matalon , M.D., David Myerberg , M.D., Irwin A. Schafer , M.D.

Pediatrics Publications

Abstract

Children with inborn errors of urea synthesis accumulate ammonium and other nitrogenous precursors of urea, leading to episodic coma and a high mortality rate. We used alternative pathways for the excretion of waste nitrogen as substitutes for the defective ureagenic pathways in 26 infants. These pathways involve synthesis and excretion of hippurate after sodium benzoate administration, and of citrulline and argininosuccinate after arginine supplementation.

The children were treated for seven to 62 months; 22 survived. The mean plasma level of ammonium (±S.E.) was 36±2 μmol per liter, and that of benzoate was 1.5±1.0 mg per deciliter. Alternative pathways accounted …

The X-Ray (1982)

The X-Ray (MCV, 1913-2010)

The yearbook of the Medical College of Virginia.

Research In Action (1982-09)

Research in Action, 1975-1987

A publication devoted to describing the scholarly and creative activities of Virginia Commonwealth University.

Virginia Dental Journal (Vol. 59, No. 2, 1982)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 59, No. 1, 1982)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 59, No. 5, 1982)

Virginia Dental Journal

No abstract provided.

Design: A Critique Of A Metaphor, Nancy R. Johnson

Journal of Social Theory in Art Education

Teaching art is basically a process of sharing socially derived knowledge about art with other persons. In order to communicate the cognitive configuration of art as it appears in our culture, it is necessary to use language. In art education, the visual arts are often thought of as a non-verbal symbol system for encoding experience. For this symbol system to be socially known about, however, it must be codified in language. As Hertzler has pointed out, "The key and basic symbolism of man is language. All the other symbol systems can be interpreted only be means of language?". Language is …

Health Risk Appraisal And Health Promotion Behavior In Young Adults, Diane L. Hanna

Theses and Dissertations

Health Risk Appriaisal (HRA) is gaining widespread popularity as a health promotion strategy. Yet there are limited studies to date to assess the impact of HRA on health behavior, particularly among young populations. The purpose of this investigation was to determine the effectiveness of individual HRA results as a stimulus for young adults to pursue health promoting behavior. It was hypothesized that young adults exposed to the results of their personal HRA would demonstrate a significantly higher health habits change score than would young adults given the HRA, but not exposed to its results.

A pretest-posttest, control group design was …

Effects Of Pulsed Electric Fields On Mammalian Cell Membranes, Guy K. Smith

Theses and Dissertations

The effect of pulsed electric fields on cell membranes were studied to investigate the effects of an electric field, per se, on biological systems, without the densometric and other technical problems associated with other forms of nonionizing radiation. Exposure of mouse splenocytes to a high voltage pulse resulted in an increase in membrane permeability to K⁺ that was dependent on both the electric field strength and the pulse duration. Exposure to a 2 μsec, 3.0 kV/cm pulse elicited a 50% loss of intracellular K⁺ indicating that the critical transmembrane potential (V_m) at breakdown was 1.26 volts …

Some Developmental Components Of The Career Decision Making Process Among College Students, Glenn Thomas Gould

Theses and Dissertations

Current research suggests that there is some relationship between developmental variables, levels of career maturity and career decisions. In this study, the relationships between certain developmental factors and the degree of certainty expressed by college students about their decision to major in a field of study were explored. The variables included the student's decision making stage, decision making styles, levels of autonomy and interpersonal relationships, and degree of career maturity. The relationships between students' status as decided or undecided about a choice of major and the variables were also investigated. The participants of this study were 104 men (n=47) and …

The Getting Of Taste: A Child’S Apprenticeship, Cathy Brooks

Journal of Social Theory in Art Education

Childhood art experience reflects an apprenticeship to the taste systems which a child's family and the public school subscribe to. This paper sketches my own taste experiences as a school child advancing from age six to eleven. Taste is used here to mean a person's ability to discern among alternatives. Taste judgments rely on not only aesthetic criteria but also status and economic criteria that are part of the social context in which one makes choices in objects and images. Understanding this childhood apprenticeship reveals some of the factors influencing participation in art activity and aesthetic choice. I will outline …

The Journal Of Social Theory In Art Education

Journal of Social Theory in Art Education

Art Education that is socially relevant and responsible is the shared goal that brought a group attending the 1979 National Art Education Association Convention to form the Caucus on Social Theory and Art Education. Since then the Caucus has expanded both its membership and its endeavors to focus the art education profession on the importance of critical socio-cultural understanding. This issue of the BULLETIN, our second, reflects the progress we have made. Twice the size of the inaugural issue, this BULLETIN includes twelve of the many papers on the Caucus Program at the 1981 NAEA Convention. The ideas and issues …

Virginia Dental Journal (Vol. 59, No. 6, 1982)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 59, No. 3, 1982)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 59, No. 4, 1982)

Virginia Dental Journal

No abstract provided.

Postmortem Stability Of Drugs In Blood And Tissues, Barry Steven Levine

Theses and Dissertations

The delay that occurs between specimen acquisition and analysis in clinical and forensic toxicology requires the establishment that no changes in drug concentration have occurred during this timed interval. In this research, severai groups of common drugs were examined for stability in serum, blood and tissues at room temperature and at 4°C. Specifically, benzodiazepines, barbiturates, lidocaine, procainamide and nortriptyline were studied. Decreases were found in the following drugs: chlordiazepoxide, norchlordiazepoxide, demoxepam, and nitrazepam. No changes were found in the other drugs. More detailed work was performed on chlordiazepoxide (CDP). Two breakdown products, demoxepam and nordiazepam (ND) were identified and quantitated. …

The Influence Of Assertiveness Characteristics Of Raters On Perceived Assertiveness In Others, Elise Heffelfinger Labe Sloan

Theses and Dissertations

The present study examined the perceptions of assertiveness, limited to the situation of ability to refuse requests, by assertive and nonassertive subjects as they rated assertive and nonassertive encoders. Gender differences were also assessed. Subjects were 40 Caucasion male and female undergraduate General Psychology students at a large urban university. Within each gender group there were 10 high-assertive and 10 low-assertive subjects as determined by their scores on the second part of the Conflict Resolution Inventory. The subjects rated videotaped assertive and unassertive encoders on an attractiveness scale, assertiveness scale, and on the Impact Message Inventory, (an interpersonal assessment instrument). …

Interfacial Electrochemistry Of Cytochrome C And Myoglobin, Edmond F. Bowden

Theses and Dissertations

The interfacial electrochemistry of horse heart cytochrome c was studied at metal and metal oxide electrodes. Sperm whale myoglobin reactions at metal oxide and surface modified electrodes were also investigated. Emphasis was on the measurement and mechanistic interpretation of the heterogeneous electron transfer kinetic parameters for these electrode reactions.

The motivation for this study stems from the fact that some electron transfer proteins, e.g., cytochrome c, transfer electrons heterogeneously in physiological systems. Specific electrodes may, therefore, serve as suitable models for physiological surfaces. Electrode and membrane interfaces are both electrically charged and both have oriented hydration water layers.

The cyclic …

Supramedullary Afferents To The Nucleus Raphe Magnus In The Rat: A Study Using Transcannula Hrp-Gel And Autoradiography Techniques, Susan Mary Carlton

Theses and Dissertations

The nucleus raphe magnus (NRM) is known to play an important role in a descending antinociceptive system through its projections to the spinal cord dorsal horn and trigeminal subnucleus caudalis. Identifying those nuclei which project to NRM is essential in determining other CNS cell groups which could influence analgesic mechanisms by virtue of their connections with NRM.

In an attempt to define NRM afferents, 19 adult Sprague-Dawley rats were stereotaxically implanted with a pellet of HRP gel within NRM and in adjacent areas. A transcannula technique was specifically developed for the subcortical placement of HRP in a gel form. Use …

Synthesis Of 3-(Substituted-Aryl)-1,2,3,4-Oxatriazolium-5-Olates As Potential Hypotensive Agents, Mary Quinn Lund

Theses and Dissertations

Hypertension or high blood pressure is a major cause of illness and death in the United States today.^1,2 An estimated thirty-six million people suffer from this disease.³ Prolonged hypertension and its attendant strain on various organs may cause heart failure, brain stroke or kidney damage.⁴ Usually, a pressure of 140/90 mm Hg is taken to be the dividing line between normotension and hypertension.^5,6

The hypertensive condition is generally characterized as either primary (essential) hypertension or secondary hypertension.¹ A specific cause can be identified in secondary hypertensive patients, such as, pheochromocytoma or adrenal tumor. These causes …

An Evaluation Of The Central Neurotoxic Effects Of Aroclor 1254, A Commercial Mixture Of Polychlorinated Biphenyls, In Mice, Diane L. Rosin

Theses and Dissertations

Polychlorinated biphenyls (PCBs) are industrial compounds whose ubiquitous environmental contamination has been known since the late 1960's. Incidents of human intoxication have been reported, most notably, the "Yusho" incident that affected over 1600 people in Japan in 1968. A broad spectrum of adverse effects are produced by PCBs, including some neurological symptoms. While examination of the toxic effects of PCBs has received much attention, there has been little work on the neurotoxicity of PCBs. The intent of the experiments presented in this thesis is to provide further information on the central neurotoxicity of PCBs in mice.

A commercial mixture of …

Person-Environment Interaction In Nursing Homes For The Elderly, Stan J. Orchowsky

Theses and Dissertations

There has been a growing interest in recent years in the study of person-environment interaction in the elderly. Several theoretical models have been proposed in the gerontological literature. Each of these models suffers from one or more limitations, including the restriction of requiring that the person and the environment be measured in the same terms, and the difficulty posed by attempting to empirically test the model.

A new model of person-environment interaction in the elderly is proposed here. The model views life satisfaction as the ultimate outcome variable. Feelings of personal control and choice are seen as intervening between life …

Vcu Today (1981-12-02)

VCU Today, 1972-1988

VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.

Vcu Today (1981-11-18)

VCU Today, 1972-1988

VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.

Commonwealth Times 1981-11-10

Commonwealth Times, 1969-

No abstract provided.

Vcu Today (1981-11-04)

VCU Today, 1972-1988

VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.

Commonwealth Times 1981-11-03

Commonwealth Times, 1969-

No abstract provided.

The Scarab (1981-11)

The Scarab, 1952-2010

From the cover: "Official Organ of the Alumni Association of the Medical College of Virginia."

Commonwealth Times 1981-10-27

Commonwealth Times, 1969-

No abstract provided.

Vcu Today (1981-10-21)

VCU Today, 1972-1988

VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.