Digital Commons Network^™

Interleukin-6 Inhibition For Patients With Acute Myocardial Infarction: A Systematic Review And Meta-Analysis, Mohammed Y. Alasmary, Mohammed J. Almalki, Faisal H. Almalki, Waleed D. Khubzan, Mohammed H. Rajab, Mohammed S. Almalki, Hussam A. Almalki, Omar M. Alsuwat, Hussam M. Alghannami

Saudi Medical Journal

Objective: To explore the outcomes associated with interleukin-6 (IL-6) pathway blockade, using tocilizumab, in patients with ST-elevation myocardial infarction (STEMI) and non (NSTEMI). Acute myocardial infarction (AMI) denotes myocardial necrosis due to ischemia and presents in distinct electrocardiographic phenotypes. Inflammation driven by IL-6 contributes to ischemia-reperfusion injury, with tocilizumab showing promise in reducing myocardial damage and improving outcomes.

Methods: This work followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Framework and was registered in international prospective register of systematic reviews (PROSPERO). Relevant studies were identified through structured searches of PubMed, MEDLINE, the Cochrane Library, and Google Scholar up …

Effect Of Anesthetic Agents On Middle Ear Pressure: Systematic Review And Meta-Analysis, Nasser Almujaiwel, Reem Alkublan, Latifah Almakoshi

Saudi Medical Journal

Objective: To assess and compare the effects of these agents on middle ear pressure (MEP). Anesthetic agents can significantly alter MEP, which is a critical factor in middle ear surgeries that require stability to prevent complications. Different anesthetics, including inhalational and intravenous agents, have varying effects on MEP.

Methods: A systematic search was conducted across PubMed, Embase, the Cochrane Library, and Scopus, following preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines. Studies that evaluated MEP changes before and after anesthesia using tympanometry were included. Relevant data, such as anesthetic type, patient demographics, MEP measurements, and reported complications, were …

The Impact Of Exercise Intervention On Pulmonary And Physical Function In Patients With Cystic Fibrosis: A Comprehensive Systematic Review, Abdullilah Alghamdi, Muroj Al-Attas, Abrar Radhi, Amnah Alfaqih, Bashair Aljabri, Rawan Alharbi, Sumayyah Alsubaie, Raneem Aljawaied, Sarah Alenazi, Ahlam Mazi, Ebtehal Qulisy

Saudi Medical Journal

Objective: To evaluate the effect of various exercise interventions on lung function, specifically forced expiratory volume in 1 second (FEV₁), maximum inspiratory pressure (MIP), and maximum expiratory pressure (MEP), as well as on cardiorespiratory fitness (peak oxygen uptake [VO₂peak]), and muscle strength (handgrip strength). The review also considers factors such as patient adherence, follow-up duration, and statistical significance to inform clinical practice.

Methods: This systematic review followed preferred reporting items for systematic review and meta-analysis (PRISMA) guidelines and was prospectively registered in international prospective register of systematic reviews. PubMed, Google Scholar, OVID, and Web of Science …

Diagnostic Timeliness And Pre-Implant Nonverbal Development In Thai Children With Severe-To-Profound Sensorineural Hearing Loss: A 2017–2024 Retrospective Review, Wanpen Ritthita, Sureelak Sutchritpongsa, Pat Rojmahamongol, Prakasit Wannapaschaiyong

Journal of Child Science

Background: Congenital severe-to-profound sensorineural hearing loss (SNHL) may compromise early development, and timely cochlear implantation (CI) is essential; however, data from low- and middle-income countries, where universal newborn hearing screening is limited and referral is delayed, remain scarce. This study describes diagnostic timeliness and CI referral in Thai children with congenital severe-to-profound SNHL, and reports age-stratified pre-implant nonverbal developmental profiles as secondary contextual descriptive data. Methods: A retrospective chart review was conducted at Siriraj Hospital, Bangkok, Thailand. Children with congenital severe-to-profound SNHL who underwent pre-CI developmental or non-verbal cognitive assessments between January 2017 and December 2024 were enrolled. Data on …

Enhancing Visual-Spatial And Social Communication Skills In Children With Autism Through The Autistic Ready To Play Program, Adidsuda Fuengfoo, Nipontorn Saengthongsri, Pentrakarn Saengthongsri, Netsai Thongchamrat, Nutchanat Promiam, Montika Rattanaruengsin, Lutlawan Lamomsai, Pongpun Jinpla

Journal of Child Science

Background: Autism Spectrum Disorder (ASD) is characterized by deficits in social communication and repetitive behavioral patterns. Leveraging the strong visual learning abilities of children with ASD, the Autistic Ready to Play (ARP) program was developed to improve visual-spatial skills, spatial reasoning, and social communication through structured, play-based activities. Objective: This study aims to identify the impacts of the ARP program on language, social communication, sensory perception, physical health, and behavioral dimensions in autistic children. Methods: This study included 99 children with ASD, aged 4–10 years, who were randomly assigned to three groups. Group 1 received standard developmental care, while Groups …

Pharmacovigilance For Health Management: A National Profile Of Methylphenidate Adverse Events In Thailand Using National Databases, Suwapat Sukthas, Pornpan Soontorntham, Surasak Saokaew

Journal of Health Research

Background: Methylphenidate, a Schedule II psychostimulant, is indicated for ADHD in children ≥6 years when other measures fail, with unclear adult indications beyond narcolepsy. Global use increases necessitate robust pharmacovigilance, especially in low/middle-income countries like Thailand where safety data is sparse. This study characterized methylphenidate-associated adverse events (AEs) in Thailand, analyzing product types and patient factors.

Methods: Spontaneous Thai Vigibase™ reports (2005-2024) were analyzed alongside national distribution data. AEs were MedDRA-coded and stratified by age, sex, indication, formulation (original/generic; immediate/extended-release), allergy history, and comorbidities. Reporting Odds Ratios (RORs) identified safety signals. Serious AEs followed WHO criteria.

Results: Among 424 patients …

Cure Sickle Cell Initiative Recommendations On Common Data Elements For Sickle Cell Disease Gene Therapy Trials, Sophie Lanzkron, Victoria H. Coleman-Cowger, Alexis A. Thompson, C. Patrick Carroll, Traci Clemons, Michael Debaun, Julie Kanter, Punam Malik, Deepa Manwani, Francis John Pierciey, Mark C. Walters, Sherita Alai

Cardeza Foundation for Hematologic Research

The Cure Sickle Cell Initiative (CureSCi), created by the National Heart, Lung, and Blood Institute, has developed data standards to increase interoperability and meta-analysis of studies specifically investigating gene therapy for sickle cell disease (SCD). The aims of the CureSCi Common Data Elements (CDE) initiative are to facilitate the development of safe, effective, and accessible gene therapies. Five working groups (WGs) comprising people living with SCD, stakeholders, clinicians, and researchers reviewed current definitions used for SCD clinical studies, including those from the American Society of Hematology, US Food and Drug Administration, PhenX catalog of consensus measures for phenotypes and exposures, …

Disability Rates Among South Asian Immigrants In The U.S. Vary By Country Of Origin, Sobia Mushtaq, Marc A. Garcia

Population Health Research Brief Series

South Asian immigrants are often grouped together in U.S. health data, masking significant differences in health outcomes across subgroups. This brief uses data from the American Community Survey (ACS) 5-Year Public Use Microdata Sample (N = 6,643,738; 2020–2024) to describe disability rates among foreign-born adults from India, Pakistan, and Bangladesh residing in the U.S. The authors find that while South Asian immigrants as a group have lower disability rates than U.S.-born adults, this average is driven largely by Indian immigrants, who make up about 79% of South Asians in the U.S. Among adults aged 65 and older, Bangladeshi immigrants have …

Distance And Trade Elasticity: The Red Sea Crisis As A Natural Experiment, Felix C. Feldman

Economics Undergraduate Senior Theses

This paper exploits the 2023 Houthi attacks on shipping through the Bab el-Mandeb Strait at the entrance to the Red Sea and the subsequent mass rerouting around the Cape of Good Hope to estimate modern-day elasticities with respect to effective trade cost. This event is unique among chokepoint disruptions as it did not lead to a complete blockage. Instead, many ships voluntarily rerouted away the area, but not all. This paper uses a structural approach to infer unobservable costs incurred by inframarginal Red Sea shippers. This paper combines a reduced-form gravity specification with a discrete route-choice model where ships select …

Exploring The Impact Of Leadership Development On The Sense Of Belonging Among Collegiate Black Men, Todd Lamont Jenkins

Theses and Dissertations

This qualitative case study used Strayhorn’s Sense of Belonging Model (2018) to examine how collegiate Black men experienced affirmation, connection, and mattering through participation in Leaders of the Free World (LFW), a culturally grounded program integrating mentoring, leadership development, and short term study abroad. Through semi structured interviews, a focus group, and document analysis, five themes emerged: (1) Global Exposure and Cultural Heritage, (2) Identity Development, (3) Academic Realignment, (4) Mentoring and Relationship Growth, and (5) Leadership Capacity Building. Findings show that LFW fostered the core belonging conditions Strayhorn (2018) identifies: psychological safety, meaningful relationships, validation, and institutional navigation support. …

U.S. Black Men’S Perceptions Of The Similarities And Interplay Among Mind-Body Practices, Spirituality, And Religion: A Qualitative Study, Khanh Pham

Theses and Dissertations

This qualitative study explored U.S. Black men’s perceptions of relations among mind-body practices (MBPs), spirituality, and religion to understand how these factors might influence Black men’s health. Reflexive thematic analysis was used to analyze data from individual semi-structured interviews with 18 Black male MBP instructors. Five themes were generated. The themes were (1) spirit(uality) is the foundation for Black men’s experience of life seen and unseen, (2) MBPs and religion are rooted in spirituality, (3) MBPs, religion, and Black culture share common characteristics, (4) MBPs and religion facilitate holistic wellbeing, and (5) confusion and negative perceptions about MBPs, spirituality, and …

Testing The Moderating Effect Of Self-Compassion On The Relationship Between Perfectionism-Related Discrepancy And Perceived Social Support From Family, Marinne Hammond

Theses and Dissertations

Perfectionism involves an insistence on outstanding performance on tasks to an extreme level. More specifically, perfectionism-related discrepancy is when one subjectively sees a gap between their performance and their expectations for how they should perform. Perfectionism may be linked to mental health issues, such as anxiety, depression, eating disorders, and social disconnection. The perfectionism social disconnection model asserts that perfectionism can also lead to social withdrawal. Self-compassion involves the acceptance of imperfection; it has been associated with higher perceived social support and has also been shown to attenuate the relationship between perfectionism and psychological distress. This study aimed to further …

A Qualitative Study Of People With Aphasia And Their Experiences With The Bible, Marin Li

Theses and Dissertations

This phenomenological study explores the lived experiences of 4 individuals with aphasia (1 female, 3 male; 3 Catholic, 1 Lutheran) regarding their relationship with and engagement with the Bible. Participants completed three remote sessions via Zoom. In Session 1, participants completed the Test of Nonverbal Intelligence, Fourth Edition, (TONI-4), and the remote Quick Aphasia Battery (QAB). In Session 2, participants engaged in a semi-structured interview led by the researcher. In Session 3, the researchers presented preliminary analysis to receive feedback from participants. Student researchers coded interview transcriptions to develop a structured codebook. Five primary themes describe the participants' experiences with …

Investigation Of Electrochemical Transport, Gate Leakage, And Transconductance Behavior In Pedot:Pss Organic Electrochemical Transistors, Vinay Bhudhraja, Bilal Khan, Abijeet Mehta

Health & Biomedical Sciences Faculty Publications

Organic Electrochemical Transistors (OECTs) are promising candidates for low-voltage bioelectronic systems due to their high transconductance, mixed ionic–electronic transport, and compatibility with flexible substrates. In this work, we investigate the electrochemical transport, gate leakage, and transconductance behavior of screen-printed PEDOT:PSS OECTs, with emphasis on the relationship between ionic coupling and output characteristics. Key electrical and electrochemical parameters—including drain current modulation, transconductance evolution, gate current behavior, and capacitance–voltage response—were systematically analyzed to elucidate the mechanisms governing device operation. The results reveal clear trade-offs between parasitic resistance, volumetric electrochemical capacitance, and effective gate control, which in turn influence signal integrity and amplification …

Methylglyoxal And Glyoxal In High-Puff Disposable Electronic Cigarette Liquids: Unexpected Accumulation And Enhanced Cytotoxicity, Esther E. Omaiye, Wentai Luo, Kevin J. Mcwhirter, Man Wong, Prue Talbot

Civil and Environmental Engineering Faculty Publications and Presentations

Despite concerns regarding the potential health risks associated with EC use, their design, puff count, and e-liquid formulations have continued to evolve. Aldehydes are a key class of thermal degradation byproducts generated during the vaporization of EC fluids. This study tested the hypothesis that aldehyde concentrations would be elevated in used ECs with high puff numbers. Devices from multiple brands were analyzed to assess the impact of extended use on aldehyde formation. E-fluids were extracted from field-collected and user-donated devices and analyzed using gas chromatography/mass spectrometry to quantify 178 flavor chemicals, two synthetic coolants, nicotine, solvents, and aldehydes (methylglyoxal (MGO), …

Practical Engineering Design: Hands-On Learning In An Undergraduate Embedded Systems Design Course, Nadieh Moghadam

School of Engineering: Faculty Scholarship

Hands-on engineering design can help bridge the gap between theoretical coursework and real-world engineering practice, particularly during the middle years of undergraduate programs. This paper presents the implementation and outcomes of an open-ended final project in ELEC 310: Embedded Systems Design at the University of San Diego. Student teams designed and prototyped smart environmental monitoring systems using STM32 microcontrollers, selecting sensors and defining system objectives under realistic constraints. Project outcomes were evaluated using prototype demonstrations, team technical reports, and post-project student reflections analyzed through inductive thematic analysis. Reflections and project artifacts suggest that debugging and hardware–software integration functioned as key …

Flourishing, Social Participation And Reintegration Difficulties: A 2-Year Cohort Study Of Us Military Veterans With Invisible Injuries, Nicholas A. Rattray, Mindy Flanagan, Richard M. Frankel, Marina Kukla

Health Services and Informatics Research

Introduction:

Longitudinal research examining community reintegration among military veterans with invisible injuries remains limited, despite widespread recognition that post-separation adjustment encompasses multiple interconnected domains including mental health, physical health, social functioning, and overall well-being. This study investigated associations between changes in reintegration outcomes and changes in health-related quality of life, social support, and flourishing over a two-year period among U.S. military veterans with invisible injuries who separated from service within the previous five years.

Methods:

Seventy-five veterans diagnosed with invisible injuries (post-traumatic stress disorder, anxiety, depression, traumatic brain injury, or adjustment disorder) completed assessments at baseline, 6, 12, 18, and …

Research & Innovation Advisory Group Terms Of Reference, Munster Technological University, Ireland

Policies & Procedures Documents

The Research & Innovation Advisory Group (RIAG) provides strategic advice, insights, and recommendations on research and innovation initiatives to the Vice President Research & Innovation (VPRI) and, where appropriate, to the University Executive. It is focused on supporting executive decision-making in research and innovation, fostering institutional research excellence, and identifying emerging opportunities for innovation and partnerships.

Procedure For Managing Allegations Of Research Misconduct And Unacceptable Research Practices, Munster Technological University, Ireland

Policies & Procedures Documents

This document outlines the procedure to be used to manage allegations of Research Misconduct and Unacceptable Research Practices within the University. While breaches of research integrity1 are typically driven by allegations, the University reserves the right to take a proactive approach to promote research integrity and to initiate the procedure set out in this document in any case where it considers it appropriate to do so. This procedure details the sources of help available to all those to whom the procedure applies. The University promotes and encourages the resolution of allegations of Research Misconduct and Unacceptable Research Practices through informal …

Lindenwood Expands Its Role In The St. Louis Geospatial Ecosystem, Lindenwood University

Archived Lindenwood Press Releases

No abstract provided.

June 9, 2026 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

The Invisible Disease Made Visible: A Qualitative Inquiry Into The Lived Experience Of Cold Agglutinin Disease Patients, Paul Mowry

Electronic Theses and Dissertations Archive

The purpose of the phenomenological study was to better understand the lived experience of Cold-Agglutinin Disease (CAD) patients. Eleven white female participants who had moderate to severe symptoms of CAD were recruited via a CAD support group on Facebook and were prompted with a series of open-ended questions about their lived experience with CAD. Interview questions focused on how vital life domains (i.e., mental and physical health, family, community, and work) are impacted by CAD, how CAD patients experience the medical and mental health system, CAD patients’ perceptions of the medical healthcare they received, and their recommendations for how medical …

The Psychosocial Factors Influencing Hiv Testing Among Women In Ghana, Janet Okailey Okine

Electronic Theses and Dissertations Archive

HIV testing is still an important component of HIV prevention, and disparities persist among women in Ghana. This study examines psychosocial and socio-demographic factors influencing HIV testing behavior, using data from the 2022 Ghana Demographic and Health Survey. A binary logistic regression result revealed that older, more educated, and wealthier women, and women who utilized HIV test kits, exhibit a much higher likelihood of undergoing HIV testing. Awareness of HIV stigma reduces the likelihood of women undergoing testing. Variations existed depending on the place of residence. Women in rural and northern belts were less likely to undergo testing. Marital status, …

“Your ‘Magic Dick’ Won’T Fix Us”: The Lived Experience Of Women With Vaginismus, Alisun Fiona Hughes

Electronic Theses and Dissertations Archive

Genito-Pelvic Pain/Penetration Disorder, or what is commonly referred to as Vaginismus, is a pelvic floor dysfunction which causes penetration of the vagina to be painful or impossible. This qualitative study examines the lived experiences of women living with vaginismus, looking specifically at how they were socialized to perceive sex and how they navigate their condition. Grounded in theories such as Sexual Scripts Theory, Stigma Theory and Gender as Performance, this research analyzes how this condition is not just a biological trait, but also a socialized phenomenon that often causes a “spoiled identity”. Data was collected through an open-ended online survey …

A Text Message Health Intervention For Cervical Cancer And Hpv Education And Behavioral Intentions Related To Screening And Vaccination, Carla G. Mercer

Electronic Theses and Dissertations Archive

This study examined the effectiveness of a technology-based educational intervention delivered exclusively through text messaging to increase knowledge of cervical cancer and HPV infection and behavioral intentions to obtain Pap test screening and HPV vaccination. A two-arm randomized controlled trial with a pretest-posttest structure was administered to 33 enrolled college students ages 18–26 years, with 29 participants completing both assessments and included in the final analysis. Participants were randomly assigned to a treatment group, which received a one-week text message-based health intervention, or a control group, which received no intervention. Pretest and posttest surveys evaluated knowledge regarding cervical cancer and …

Comparative Analysis Of Leaflet Materials, Stent Materials, And Stent Cell Density For Bileaflet Transcatheter Mitral Valve Design, Joseph Chibuike Nwokeafor, Joshua D. Hofmeister, Breandan B. Yeats, Lakshmi Prasad Dasi, Charanjit S. Rihal, Juan A. Crestanello, Leigh Griffiths, Mohamad A. Alkhouli, Hoda Hatoum

Michigan Tech Publications

Background: The biomechanical performance of bileaflet transcatheter mitral valves (TMVs) depends on complex interactions between leaflet material behavior and stent design. However, the contributions of leaflet materials and constitutive models, stent materials, and stent geometry to valve function and durability remain poorly understood. Methods: A parametric finite element study was conducted using a CAD model of a bileaflet TMV subjected to physiological pressure loading. Five leaflet material models were evaluated: 3 glutaraldehyde-fixed tissues—bovine pericardium (BP; FBP1, FBP2) and porcine pericardium (PP; FPP)—and 2 unfixed tissues—bovine (UBP) and porcine pericardium (UPP). BP was modeled as a linear elastic (FBP1) and Ogden …

Ora (Oneball Robotic Arm), Isabella Murillo, Juan Pablo Fernandez Garza, Gabriel Kotab, Catherine Epstein

Electrical and Computer Engineering Senior Theses

Confined spaces are dangerous and awkward to navigate environments, often putting those who work in them at risk. To reduce effort and human exposure to these hazards, robotic systems can be used to navigate and inspect these areas to limit, or even eliminate the need for human presence in confined spaces. This project proposes an autonomous robot that can navigate confined spaces while sending data back to the user. The robot features a spherical body that is capable of a zero rotational axis, with an external, magnetically attached head. This head contains scanners or tools that the user can remotely …

Gesture Control Reminder Device, Ian Kennar, Ryan Kiniris, Veronica Saltanov

Interdisciplinary Design Senior Theses

Individuals with special needs or attention deficit disorders struggle to maintain structured daily routines independently, yet existing reminder technologies rely on visual interfaces, touchscreens, and fine motor control that make them inaccessible to this population. The Gesture-Controlled Reminder Device addresses these shortcomings through a compact, wearable assistive technology that eliminates these barriers entirely.

Teachers and caregivers can record personalized voice reminders directly onto the device, which are delivered to the user through haptic vibration and interacted with via simple hand gestures to repeat, snooze, or dismiss them. By processing all interactions on a custom PCB built around the Raspberry Pi …

Studyscape, Sanaa Ahmed, Zach Anderson, Joshua Colleran, Tiffany Doan, Andrew Pritchard

Interdisciplinary Design Senior Theses

Finding suitable places to study or work on a college campus can be challenging due to fluctuating noise levels and overcrowding in shared spaces. This project, titled StudyScape, aims to help students identify optimal study environments by providing real-time information on ambient noise and room occupancy in campus buildings. The system deploys edge-based sensing nodes in selected indoor locations, each equipped with a microphone and camera. Audio signals are processed locally to estimate noise levels, while computer vision techniques are used solely for accurate occupancy counting; no video or image data is stored or transmitted, ensuring user privacy. A mobile …

Positive Partner Support And Veteran Well-Being: How Capitalization Support Strengthens Military Veterans And Partnerships, Maryann Dona Samson

Dissertations and Theses

Among military veterans, the transition to civilian life is often marked by elevated distress and burnout, low job satisfaction, and a lack of perceived psychological safety. Social support, especially from intimate partners, can serve as a critical protective factor. While most support literature focuses on stress-buffering in adverse contexts, positive social support, such as responsiveness to shared positive experiences (i.e., capitalization support), is a powerful though understudied process. This dissertation investigates the role of partner capitalization support, which is the responsiveness shown by a romantic partner when one shares good news, as a source of stress reduction, resilience, and relational …