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The State Of Insulin In The Blood, Thaddeus E. Prout Jan 1966

The State Of Insulin In The Blood, Thaddeus E. Prout

MCV/Q, Medical College of Virginia Quarterly

Diabetes mellitus has been reviewed as a group of conditions with impaired function of one or more portions of a feed-back system involving the release and utilization of insulin. It is hoped that this may form a useful scheme by which we can study and understand a number of complex metabolic states which we must still collectively refer to as diabetes mellitus.

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Insulin Antigenicity, Thaddeus E. Prout Jan 1966

Insulin Antigenicity, Thaddeus E. Prout

MCV/Q, Medical College of Virginia Quarterly

Thus we have seen that evidence of insulin antigenicity in one or more forms is present in most individuals receiving intermediate insulins for six weeks or longer. A number of clinical manifestations of insulin antigenicity and their treatment have been discussed.

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Insulin Antagonists, John A. Owen Jr. Jan 1966

Insulin Antagonists, John A. Owen Jr.

MCV/Q, Medical College of Virginia Quarterly

In conclusion, the synalbumin antagonist exists, and may be important in the pathogenesis of human diabetes, but its role has not been proved. The proof will require elucidation of the problem of species specificity, and ability to measure accurately the levels of synalbumin antagonist.

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Cholinergic Responses Of Schistosoma Mansoni, Ernest Bueding Jan 1966

Cholinergic Responses Of Schistosoma Mansoni, Ernest Bueding

MCV/Q, Medical College of Virginia Quarterly

It is concluded that the use of pharmacological agents can provide opportunities to recognize and define similarities and differences in the mechanisms of transmission of nerve impulses in the parasite and the mammalian host. Such studies contribute to better understanding of comparative physiology and of the mode of action of antiparasitic drugs.

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Recollections Of Professor Otto Meyerhof, Chalmers L. Gemmill Jan 1966

Recollections Of Professor Otto Meyerhof, Chalmers L. Gemmill

MCV/Q, Medical College of Virginia Quarterly

Professor Meyerhof's laboratory represented the Institute approach with all of the workers devoting their attention to the several aspects of the single problem of muscle metabolism. The number of papers (Meyerhof, 1930) and the great contributions from this laboratory represent the results of the dominant personality of one man. The tributes (Nachmansohn, 1950) paid to him in 1950 were published in Metabolism and Function. Comparable tributes are now being given to Dr. Fischer upon his retirement.

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Clinicopathological Conference: Complications Of Rheumatoid Arthritis, P. Franklin Mullinax, R. Page Hudson Jr. Jan 1966

Clinicopathological Conference: Complications Of Rheumatoid Arthritis, P. Franklin Mullinax, R. Page Hudson Jr.

MCV/Q, Medical College of Virginia Quarterly

Clinicopathlogical conference transcript from the Medical College of Virginia. Discussants include P. Franklin Mullinax and R. Page Hudson.

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The Patient Has The Floor, Alistair Cooke Jan 1966

The Patient Has The Floor, Alistair Cooke

MCV/Q, Medical College of Virginia Quarterly

Address given before the Annual Convocation of the Mayo Graduate School of Medicine, Rochester, Minnesota, on May 28, 1965.

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Effects Of Salmonella Vaccination On Metabolism And Resistance To Infection Of Rabbit Peritoneal Cells, Marvin J. Allison, Enrique Gerszten, Blanca Sanchez Jan 1966

Effects Of Salmonella Vaccination On Metabolism And Resistance To Infection Of Rabbit Peritoneal Cells, Marvin J. Allison, Enrique Gerszten, Blanca Sanchez

MCV/Q, Medical College of Virginia Quarterly

Salmonella vaccine caused a depression of metabolism of peritoneal exudate cells from rabbits. This effect was associated with a depression in resistance of rabbits to infection with C. albicans. This depression in metabolism is similar to the one previously noted following BCG vaccine and associated with a depression in resistance to tuberculosis.

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Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 4 Jan 1966

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 4

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

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Problems In The Insulin Dependent Diabetic, Clay T. Gardner Jr. Jan 1966

Problems In The Insulin Dependent Diabetic, Clay T. Gardner Jr.

MCV/Q, Medical College of Virginia Quarterly

It is often useful for the physician to classify diabetes as stable or unstable. Maturity-onset diabetes is usually stable, and its management is not difficult, provided the patient is interested and cooperative. Tendency to obesity, relative insensitivity to insulin, and absence of ketosis are characteristic of such patients. Relative insensitivity to insulin does not imply unresponsiveness, but rather that the blood sugar is not overly labile and does not fall sharply in response to exercise or injected insulin. Many patients with such insensitivity to insulin are adequately managed on diet, alone or in combination with the oral hypoglycemic agents. When …

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Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 1 Jan 1966

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 1

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

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Brains Of Prominent People: History, Facts And Significance, Walther Riese Jan 1966

Brains Of Prominent People: History, Facts And Significance, Walther Riese

MCV/Q, Medical College of Virginia Quarterly

In conclusion, in the brains of outstanding right-handed people (Haeckel, Monakow, Pilsudski) the more complicated convolutional and fissural patterns were found on the left hemisphere; in those of outstanding left-handed people (Menzel, Edinger) on the right one. The second brain reported here revealed some overdevelopments on the right, others on the left hemisphere. Strangely enough, very little is known about side-differences in the average brain. It seems that the middle frontal convolution and the inferior parietal lobe are more developed on the right hemisphere, the inferior frontal convolution on the left one. Nothing is known about the handedness of the …

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A Deadly Poison Becomes A Useful Tool, John W. Moore Jan 1966

A Deadly Poison Becomes A Useful Tool, John W. Moore

MCV/Q, Medical College of Virginia Quarterly

The very high potency of TTX and its highly selective block of nerve and skeletal muscle fibers has already shed a great deal of light on their excitation properties and should lead to the ability to specify an entirely new type of anesthetic agent even if the toxin itself does not also turn out to be useful agent in this respect.

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Diabetic Glomerulosclerosis, J. M. B. Bloodworth Jr. Jan 1966

Diabetic Glomerulosclerosis, J. M. B. Bloodworth Jr.

MCV/Q, Medical College of Virginia Quarterly

Why should the mesangial cells be irritated? We recently observed in some diabetics black deposits beneath and on both sides of the basement membrane. These appear quite similar to deposits seen in and around the basement membrane in glomerulonephritis and in lupus nephritis. I do not know for sure what they are, but theory says that in glomerulonephritis they probably represent antigen-antibody complexes. There is some evidence to support this. One would assume that in diabetes they might be the same thing. Or they might be some other atypical plasma protein which results from the abnormal pattern of diabetic metabolism. …

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"Slow" And "Fast" Muscle Fibers, Ernest Gutmann Jan 1966

"Slow" And "Fast" Muscle Fibers, Ernest Gutmann

MCV/Q, Medical College of Virginia Quarterly

On the basis of the clear-cut differentiation used in fast (twitch) and slow (tonic) muscles of the frog, both the fast E.D.L. and the slow soleus muscle should be considered twitch muscles. However, they reveal a marked differential behavior in their contracture responses to ACh and caffeine. Moreover, all the slow muscles I have studied (i.e.. the L.D.A. of the chicken, the rectus abdominis of the frog, and the soleus of the rat) show a higher rate of proteosynthesis. This may be related to the basic function of slow muscles concerned with long-lasting maintenance of tension, the extreme being, for …

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Plasma Volume Expansion And Proximal Tubular Reabsorption Of Salt And Water By Rat Kidney, Sidney Solomon, Harald Sonnenberg Jan 1966

Plasma Volume Expansion And Proximal Tubular Reabsorption Of Salt And Water By Rat Kidney, Sidney Solomon, Harald Sonnenberg

MCV/Q, Medical College of Virginia Quarterly

Venous infusion of both hypertonic and isotonic solutions has been known to lead to diuresis and natriuresis. In recent micropuncture studies, attempts have been made to identify the tubular locus at which renal functions may be altered and to identify the mechanism by which functional changes are mediated. In the rat, Giebisch et al. (1964) found suppressed fractional reabsorption of sodium at the level of the distal tubule when hypertonic saline was administered, whereas suppressed proximal fractional reabsorption was found only when excreted sodium was greater than 13% of the filtered load. On the other hand, Cortney et al. (1965) …

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Contributors Jan 1966

Contributors

MCV/Q, Medical College of Virginia Quarterly

List of contributors to this issue includes Rama M. Aiyawar, Hermann K. F. Blaschko, Ernest Bueding, Addison D. Campbell, Chalmers L. Gemmill, Ernest Gutmann, Gabriel Hilkovitz, Ernst G. Huf, Elinor Langer, Nancy S. LaPrade, John W. Moore, Richard W. Ramsey, Walther Riese, J. C. Rüegg, Alexander Sandow, Michael N. Sheridan, Archibald W. Sloan, Thomas C. Smith, Sidney Solomon, Harald Sonnenberg, Frederick J. Spencer, Sibyl F. Street, Alfred J. Szumski, William R. Tolbert, Hans H. Weber, and Priscilla M. Winn.

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Cryocautery And Aqueous Humor Dynamics, Herbert Wiesinger Jan 1966

Cryocautery And Aqueous Humor Dynamics, Herbert Wiesinger

MCV/Q, Medical College of Virginia Quarterly

A method of cyclocryocautery, using the Kelman Cryostylet, is described. On rabbit eyes this brings about a statistically significant lowering of intraocular pressure and reduction of aqueous flow over an observation period of three months. The effects upon the facility of outflow are variable. Side effects are minimal. The intraocular temperature was measured at various points during and after cryocautery. An applicator temperature of about -40° C was found sufficient for the desired result with minimal side effects. Angiocryocautery of one or both long posterior ciliary vessels resulted only in a temporary reduction of intraocular pressure, as permanent obliteration of …

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Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 2 Jan 1966

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 2

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

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On The Nature Of The Resting Frog Skin Potential, Priscilla M. Winn, Nancy S. Laprade, William R. Tolbert, Ernst G. Huf Jan 1966

On The Nature Of The Resting Frog Skin Potential, Priscilla M. Winn, Nancy S. Laprade, William R. Tolbert, Ernst G. Huf

MCV/Q, Medical College of Virginia Quarterly

In this paper some of the highlights of research on the nature of the resting frog skin potential have been presented. Reviewing a period of about 30 years, it was the intention to show that several key problems have been recognized by a number of investigators who, through their experimental work, have tried to find unequivocal solutions to such problems as follows: a) The number and location of electrogenic layers (barriers) within the rather complex epidermis. b) The characterization of these barriers in terms of specific permeability properties. c) The electrical response of the two sides of the skin to …

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Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 3 Jan 1966

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 3

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

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Virus Infections--What Of The Future?, Robert J. Huebner Jan 1966

Virus Infections--What Of The Future?, Robert J. Huebner

MCV/Q, Medical College of Virginia Quarterly

The rate of progress in virus research today is so rapid that for many the present is the future. Consequently, in order to discuss the future in comprehensible fashion, I must talk about the present state of affairs--to discuss current knowledge which furnishes the basis for contemporary enormous interest in viruses. It is precisely those considerations which will furnish the springboard for future progress in understanding and controlling the effects of virus infections.

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The Pathogenesis Of Atherosclerosis And Coronary Heart Disease, Joseph T. Doyle Jan 1966

The Pathogenesis Of Atherosclerosis And Coronary Heart Disease, Joseph T. Doyle

MCV/Q, Medical College of Virginia Quarterly

Fifty-five percent of all deaths in the United States are ascribed to cardiovascular disease. The vast majority of these deaths are due directly or indirectly to atherosclerosis and its ischemic complications (Am. Heart Assoc., 1965; U.S. President's Commission on Heart Disease, Cancer and Stroke, 1964). Atherosclerosis is defined in Dorland's dictionary (24th edition) as "a lesion of large and medium-sized arteries with deposits in the intima of yellowish plaques containing cholesterol, lipoid material and lipophages." Typical atherosclerotic lesions of the coronary arteries are shown in figure 1. Even a casual inspection of these lesions shows the incompleteness of this conventional …

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Some Malpractices In Medical Statistics, James S. Kilpatrick Jr. Jan 1966

Some Malpractices In Medical Statistics, James S. Kilpatrick Jr.

MCV/Q, Medical College of Virginia Quarterly

Since it is now fashionable for papers in medical journals to contain statistical notations, it also follows that in a certain fraction of these the statistical content is wrongly applied. These malpractices may be classified as numerical, statistical, and methodological. To illustrate some of the most commonly occurring errors the following examples are given.

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Cobblestone (1966) Jan 1966

Cobblestone (1966)

Cobblestone (RPI, 1956-1968; VCU, 1969-1973)

The yearbook of Richmond Professional Institute and Virginia Commonwealth University. Vols. for 1956-1968 issued by Richmond Professional Institute ; 1969-1973 by Virginia Commonwealth University.

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Virginia Dental Journal (Vol. 43, No. 2, 1966) Jan 1966

Virginia Dental Journal (Vol. 43, No. 2, 1966)

Virginia Dental Journal

No abstract provided.

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Information From: Richmond Professional Institute, Spring Art Festival 1966 Jan 1966

Information From: Richmond Professional Institute, Spring Art Festival 1966

Bang Arts Festival Documents

A seven page typewritten press release from Richmond Professional Institute announcing the BANG, BANG, BANG Spring Art Festival, scheduled from March 21-25, 1966. The aims of the festival were "to bring to Richmond contemporary music, drama, choreography, film, painting, and graphics as well as promote discussion and contact with active creative artists from outside the immediate community." The announcements contains information about programming, artist biographies, and a list of admission prices.

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Medicovan (1968-02) Dec 1965

Medicovan (1968-02)

The Medicovan, 1948-1973

Published by: Medical College of Virginia, Feb. 1948-Aug. 1972; Virginia Commonwealth University, Sept. 1972-Feb. 1973.

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Proscript (1965-10-08) Oct 1965

Proscript (1965-10-08)

Proscript, 1940-1969

Published by the students of the Richmond Professional Institute, College of William and Mary (1940-1947); The Richmond Professional Institute and Virginia Polytechnic Institute cooperating (1947-1955); Richmond Professional Institute of the Colege of William and Mary <1955-1962>; Richmond Professional Institute, Sept. 21, 1962-May 24, 1968; Virginia Commonwealth University, Sept. 20, 1968-May 23, 1969.

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Medicovan (1967-09) Apr 1965

Medicovan (1967-09)

The Medicovan, 1948-1973

Published by: Medical College of Virginia, Feb. 1948-Aug. 1972; Virginia Commonwealth University, Sept. 1972-Feb. 1973.

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