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Articles 5101 - 5130 of 5385
Full-Text Articles in Entire DC Network
Medicovan (1969-04)
The Medicovan, 1948-1973
Published by: Medical College of Virginia, Feb. 1948-Aug. 1972; Virginia Commonwealth University, Sept. 1972-Feb. 1973.
The Scarab (1967-02)
The Scarab, 1952-2010
From the cover: "Official Organ of the Alumni Association of the Medical College of Virginia."
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 1
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 1
MCV/Q, Medical College of Virginia Quarterly
No abstract provided.
Sporotrichosis: The Significance Of Variations In Morphology Of Spores In The Tissues, Harry I. Lurie
Sporotrichosis: The Significance Of Variations In Morphology Of Spores In The Tissues, Harry I. Lurie
MCV/Q, Medical College of Virginia Quarterly
The histopathological diagnosis of sporotrichosis is briefly reviewed. The primary lesion consists basically of pseudo-epitheliomatous hyperplasia of the epidermis, intra-epidermal micro-abscesses, a non-specific dermal infiltrate and granulomata composed of central micro-abscess surrounded by a zone of histiocytes and multinucleated giant cells. The significance of the asteroid body is discussed. Evidence is presented to support the view that the development of asteroid bodies and the amount of eosinophilic material in these bodies is related to host resistance and that cigar bodies are found in those cases with little or no resistance and in whom the disease disseminates rapidly and wildly. Avenues …
The Pharmacology Of Newer Diuretics, Albert J. Wasserman
The Pharmacology Of Newer Diuretics, Albert J. Wasserman
MCV/Q, Medical College of Virginia Quarterly
There are now a number of different classes of diuretics with different pharmacologic effects. Several considerations dictate the choice of diuretic: 1. The responsiveness of the patient is of prime importance. If the patient is not known to be resistant to diuretic therapy, thiazides should be tried first. 2. The danger of alterations of volume and of electrolytes in the specific patient must be considered. Patients receiving digitalis will be subjected to much greater danger by the induction of hypokalemia than patients not receiving cardiac glycosides. 3. The pharmacologic effects of the specific diuretics must be understood for now the …
Iatrogenic Disorders, Robert H. Moser
Iatrogenic Disorders, Robert H. Moser
MCV/Q, Medical College of Virginia Quarterly
The contemporary physician and his patient are riding the crest of the most dramatic expansion of medical capability in history. But the rapid proliferation of medical knowledge has not been entirely benign. Although our reverses have been minor in contrast to our advances, negative effects cannot be ignored. My discussion involves one aspect of this problem--the emergence of what I have called "Diseases of Medical Progress" (Moser, 1964).
The Controversy Over Generic Equivalency Of Drugs, Werner Lowenthal
The Controversy Over Generic Equivalency Of Drugs, Werner Lowenthal
MCV/Q, Medical College of Virginia Quarterly
The truth about generic equivalency has not yet been determined. The arguments in the generic equivalency controversy are confounded by names, proprietary (trademark, brand name) as opposed to non-proprietary (generic, branded-generic), yet quality of the products is not necessarily related to any name. The efficacy and not the name of the product is important. The crucial question to ask is whether the product is clinically or therapeutically effective, giving reliable and uniform results.
Perspectives And Prospects In The Chemotherapy Of Gastrointestinal Cancer, William Regelson
Perspectives And Prospects In The Chemotherapy Of Gastrointestinal Cancer, William Regelson
MCV/Q, Medical College of Virginia Quarterly
5-Flourouracil (5-FU) is the best agent for the treatment of all gastrointestinal cancers but should be used with restraint, since severe toxicity does not guarantee increased response or survival time. Experimental work suggests that glucose enhances cellular uptake of 5-FU. Alkylating agents are definitely useful and occasionally produce long-term responses. Mitomycin C shows activity but is not available. There are reports of responses to methotrexate, vinca alkaloids, and mithramycin, but their place in the management of gastrointestinal cancer is not established. The usefulness of alkylating agents or 5-FU as adjuvants to surgery is not clear, but evidence is accumulating which …
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 3
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 3
MCV/Q, Medical College of Virginia Quarterly
No abstract provided.
Intracellular Co₂ Tension: Practice And Theory, Eugene D. Robin
Intracellular Co₂ Tension: Practice And Theory, Eugene D. Robin
MCV/Q, Medical College of Virginia Quarterly
I have been asked to discuss methods of measuring intracellular Pco₂ and to discuss the physiology and biochemistry of intracellular CO₂ tensions. Actually, I am in a relatively fortunate position in that my difficulties in discussing the methodology of intracellular Pco₂ measurements are considerably less than those which face my two colleagues. The reason for this becomes apparent if one analyzes the following quantitative relationships. [Includes discussion.]
The Treatment Of Anxiety, John J. Schwab, Nancy H. Mcginnis
The Treatment Of Anxiety, John J. Schwab, Nancy H. Mcginnis
MCV/Q, Medical College of Virginia Quarterly
Rational therapy requires accurate diagnosis. When we apply this precept to anxiety a fundamental question arises. Is anxiety an illness in terms of the now berated medical model which holds that an illness has a cause, a natural history, and hopefully a cure? Or is anxiety a basic aspect of the human condition, an innate pattern of response which becomes pathological when stress, induced by physiologic and social forces, is magnified out of proportion to the original stimulus? If the latter is true, then stress and social interactions are the causative factors, the anxiety only a reaction. Logically then, the …
Origins Of Congenital Defects: Epidemiologic Approach, Robert W. Miller
Origins Of Congenital Defects: Epidemiologic Approach, Robert W. Miller
MCV/Q, Medical College of Virginia Quarterly
This presentation consists of several short stories from personal experience to illustrate the complementary nature of epidemiologic and laboratory research in the study of congenital malformations.
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 2
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 2
MCV/Q, Medical College of Virginia Quarterly
No abstract provided.
Pharmacology Of Anti-Anginal Agents, Maurice Mcgregor
Pharmacology Of Anti-Anginal Agents, Maurice Mcgregor
MCV/Q, Medical College of Virginia Quarterly
In conclusion I would like to stress that these observations do not constitute direct evidence of the mechanism whereby the nitrates relieve angina pectoris. It is probable that they are capable of causing some reduction of myocardial oxygen consumption. However, there is increasing indirect evidence which suggests that the site of action of these drugs is principally on the large coronary arteries. Their administration may thus relieve coronary spasm, if this ever causes angina, and more importantly will increase collateral flow into ischemic areas of myocardium when collateral channels have become enlarged. Drugs such as dipyridamole which seem to act …
The Physician As Humanist, George T. Harrell
The Physician As Humanist, George T. Harrell
MCV/Q, Medical College of Virginia Quarterly
It is appropriate that this lecture should be given in a building which is devoted to the broader aspects of living and which is located on the campus of an institution which treats bodily ills. This institution began as part of a liberal arts college. This tradition in the state of Virginia started with Mr. Jefferson when the University was established at Charlottesville. He decreed that one of the first chairs should be in medicine, not as preparation for a professional career, but as a discipline which should be understood by all educated men. The faculty at this institution has …
Intracellular Ph Determination By Means Of Ph Glass Microelectrodes, Norman W. Carter
Intracellular Ph Determination By Means Of Ph Glass Microelectrodes, Norman W. Carter
MCV/Q, Medical College of Virginia Quarterly
A number of years ago I decided to attempt to measure the intracellular pH of skeletal muscle by a more direct method than those in current use, that is, by an electrode. I excluded all forms of pH electrodes except the glass electrode and then set up a certain number of characteristics or requirements that this electrode should have. First, the electrode should be insulated in such a manner that only the pH-sensitive portion is in the cell cytoplasm. Second, the reference side of the electrode group should also be within the cell, because the cell has a transmembrane potential; …
Medicovan (1969-02)
The Medicovan, 1948-1973
Published by: Medical College of Virginia, Feb. 1948-Aug. 1972; Virginia Commonwealth University, Sept. 1972-Feb. 1973.
The Role Of The Physician In Family Planning, Howard C. Taylor Jr.
The Role Of The Physician In Family Planning, Howard C. Taylor Jr.
MCV/Q, Medical College of Virginia Quarterly
In summary, one can find many reasons for believing that family planning programs should in general be associated with maternity services and that educational efforts should be concentrated during the weeks of pregnancy and the puerperium. During these periods the women of an age and fertility most in need of family planning are easily detectable. They are for obvious reasons interested in the subject and the most susceptible to advice. The staff needed for this work is already partly available among the physicians, nurses, midwives, and social workers connected with maternity services. The system promises to introduce birth control in …
Some Perspectives On Immunosuppressive Drugs, Robert S. Schwartz
Some Perspectives On Immunosuppressive Drugs, Robert S. Schwartz
MCV/Q, Medical College of Virginia Quarterly
In conclusion, the antimetabolites have proven extremely interesting in the laboratory for the exploration of the mechanism of antibody synthesis and related problems. They have also proven to be extremely useful and interesting materials in the clinic. Whether they are going to replace any other standard forms of therapy, such as the corticosteroids, is, in my view, doubtful. Their use at the moment is experimental and their ultimate place in clinical medicine is by no means settled. They appear to have two important effects in man: 1) Suppression of antibody formation which can be, in many individuals, selective; and 2) …
Diagnostic Ultrasonography, Joseph H. Holmes
Diagnostic Ultrasonography, Joseph H. Holmes
MCV/Q, Medical College of Virginia Quarterly
It was the development of radar and sonar during the last World War which made the ultrasonic techniques I am going to talk about possible. Following the War, Dr. K. T. Dussik had the idea that, if one directed ultrasonic waves into the body, one might obtain echoes reflected from tissue surfaces in the same way that the Navy received echo information reflected from the submarine's hull. When he did this, he did get reflected echoes from within the body, and this opened the door for other investigators to demonstrate how this echo information could be made useful in diagnostic …
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 4
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 4
MCV/Q, Medical College of Virginia Quarterly
No abstract provided.
Oxygen Tension: Direct Observations On The Critical Level For The Brain, Frans F. Jӧbsis
Oxygen Tension: Direct Observations On The Critical Level For The Brain, Frans F. Jӧbsis
MCV/Q, Medical College of Virginia Quarterly
In this lecture I want to address myself to the questions: What is the lowest oxygen tension compatible with adequate function, and what are the factors that set this limit? Much of the background to the material present here has been reviewed extensively in the not too distant past (Jӧbsis '64), and I will take the liberty of letting that article provide most of the detailed justification of my remarks today. [Includes discussion.]
Kalki, Studies In James Branch Cabell (Vol. 2, No. 1, 1967)
Kalki, Studies In James Branch Cabell (Vol. 2, No. 1, 1967)
Kalki, Studies in James Branch Cabell
No abstract provided.
The X-Ray (1967)
The X-Ray (MCV, 1913-2010)
The yearbook of the Medical College of Virginia.
Medicovan (1968-10)
The Medicovan, 1948-1973
Published by: Medical College of Virginia, Feb. 1948-Aug. 1972; Virginia Commonwealth University, Sept. 1972-Feb. 1973.
Proscript (1966-03-04)
Proscript, 1940-1969
Published by the students of the Richmond Professional Institute, College of William and Mary (1940-1947); The Richmond Professional Institute and Virginia Polytechnic Institute cooperating (1947-1955); Richmond Professional Institute of the Colege of William and Mary <1955-1962>; Richmond Professional Institute, Sept. 21, 1962-May 24, 1968; Virginia Commonwealth University, Sept. 20, 1968-May 23, 1969.
The Scarab (1966-02)
The Scarab, 1952-2010
From the cover: "Official Organ of the Alumni Association of the Medical College of Virginia."
Further Correlations Of Cell Metabolism And Resistance To Tuberculosis: Studies On Mononuclear Peritoneal Exudate Cells From Mice And Guinea Pigs, John M. Smith Jr., Marvin J. Allison, Brenda Payne
Further Correlations Of Cell Metabolism And Resistance To Tuberculosis: Studies On Mononuclear Peritoneal Exudate Cells From Mice And Guinea Pigs, John M. Smith Jr., Marvin J. Allison, Brenda Payne
MCV/Q, Medical College of Virginia Quarterly
The metabolic activity of mononuclear exudate cells from mice of different strains, and from the guinea pig, have been compared to the rabbit with the aim of relating metabolic activity of these cells to resistance of these species to tuberculosis. The presence of mast cells in the peritoneal exudates of mice was thought to interfere with the dehydrogenation of certain substrates due to the release of histamine. Some experimental evidence presented by the authors seems to support this thesis.
Clinicopathological Conference: Abnormal Sex Characteristics And Intracranial Mass, Clark T. Randt, Gerald A. Gildersleeve, Julio H. Garcia
Clinicopathological Conference: Abnormal Sex Characteristics And Intracranial Mass, Clark T. Randt, Gerald A. Gildersleeve, Julio H. Garcia
MCV/Q, Medical College of Virginia Quarterly
Clinicopathlogical conference transcript from the Medical College of Virginia. Discussants include Clark T. Randt, Gerald A. Gildersleeve, and Julio H. Garcia.
The Treatment Of Diabetic Acidosis, Thaddeus S. Danowski
The Treatment Of Diabetic Acidosis, Thaddeus S. Danowski
MCV/Q, Medical College of Virginia Quarterly
The patient with diabetes mellitus who becomes unconscious presents a problem in differential diagnosis. We now recognize six possible causes of coma in the diabetic patient. These include the usual diabetic keto-acidosis, and five possible non-ketotic causes: I. Keto-acidosis II. Non-ketotic causes of coma A. Unconsciousness unrelated to diabetes, e.g. barbiturate intoxication, "stroke," uremia B. Hypoglycemia C. Lactic acidosis D. Hypernatremia E. Hyperglycemia