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Articles 61 - 90 of 594
Full-Text Articles in Entire DC Network
Health And Quality Of Life Among People With Intellectual And Developmental Disabilities And Direct Support Professionals During The Early United States Covid-19 Pandemic, Erin Vinoski Thomas, Bridgette M. Schram, Sombal Bari, Rachel Odunlami, Kristina M. Ormond, Sydnie E. Smith
Health And Quality Of Life Among People With Intellectual And Developmental Disabilities And Direct Support Professionals During The Early United States Covid-19 Pandemic, Erin Vinoski Thomas, Bridgette M. Schram, Sombal Bari, Rachel Odunlami, Kristina M. Ormond, Sydnie E. Smith
Developmental Disabilities Network Journal
People with intellectual and developmental disabilities (IDD) and the direct support professionals (DSPs) who support them have faced unique risks to their health and quality of life (QoL) throughout the COVID-19 pandemic. We sought to understand how COVID-19 has influenced QoL and overall well-being among these populations. We conducted a Rapid Qualitative Inquiry study with a sample of people with IDD and DSPs (n = 18) to gain deeper perspectives about QoL and well-being during the pandemic. Participants described that changes in QoL were typically negative and influenced primarily by reduced socialization and impacts on health and independence; however, …
Equine Polyclonal Antibodies Prevent Acute Chikungunya Virus Infection In Mice, Douglas Barker, Xiaobing Han, Eryu Wang, Ashley Dagley, Deborah M. Anderson, Aruni Jha, Scott C. Weaver, Justin Julander, Cory Nykiforuk, Shantha Kodihalli
Equine Polyclonal Antibodies Prevent Acute Chikungunya Virus Infection In Mice, Douglas Barker, Xiaobing Han, Eryu Wang, Ashley Dagley, Deborah M. Anderson, Aruni Jha, Scott C. Weaver, Justin Julander, Cory Nykiforuk, Shantha Kodihalli
Office of Research Faculty and Staff Publications
Chikungunya virus (CHIKV) is a mosquito-transmitted pathogen that causes chikungunya disease (CHIK); the disease is characterized by fever, muscle ache, rash, and arthralgia. This arthralgia can be debilitating and long-lasting, seriously impacting quality of life for years. Currently, there is no specific therapy available for CHIKV infection. We have developed a despeciated equine polyclonal antibody (CHIKV-EIG) treatment against CHIKV and evaluated its protective efficacy in mouse models of CHIKV infection. In immunocompromised (IFNAR−/−) mice infected with CHIKV, daily treatment for five consecutive days with CHIKV-EIG administered at 100 mg/kg starting on the day of infection prevented mortality, reduced …
Improving South Dakota Parents’ Knowledge Of Congenital Cytomegalovirus, Hannah M. Williams, Jessica Messersmith, Jacynda Gellhaus
Improving South Dakota Parents’ Knowledge Of Congenital Cytomegalovirus, Hannah M. Williams, Jessica Messersmith, Jacynda Gellhaus
Journal of Early Hearing Detection and Intervention
Introduction: Congenital cytomegalovirus (cCMV) is the most common infectious condition present at birth and the leading non-genetic cause of sensorineural hearing loss in children. Despite CMV being common and preventable, knowledge of CMV remains low among individuals in the United States (Doutre et al., 2016). Sudden infant death syndrome (SIDS) is also common among infants in the United States, but unlike cCMV, several studies have researched which educational methods have been most effective for improving parents’ knowledge of safe sleep practices. The purpose of this study was to investigate whether educational methods shown to be most effective for improving parents’ …
Neonatal Abstinence Syndrome (Nas): What You Need To Know, Maren Wright Wright Voss, Amelia Van Komen, Emily Hamilton, Aarica Cleveland, Jaclyn Miller
Neonatal Abstinence Syndrome (Nas): What You Need To Know, Maren Wright Wright Voss, Amelia Van Komen, Emily Hamilton, Aarica Cleveland, Jaclyn Miller
All Current Publications
National overdose deaths continue to rise, with 2021 marking the first time U.S. overdose deaths topped 100,000 in a 12-month timeframe. Substance use, such as alcohol, cocaine, opioids, and marijuana, during pregnancy is also increasing. As the U.S. struggles with harmful substance use, a growing number of infants are born with neonatal abstinence syndrome (NAS), a harmful outcome of fetal exposure to substances. This fact sheet will talk about why and what to do, with recommendations for safe treatment and support during pregnancy.
Evidence-Based Approaches To Lowering Uti Rates In Skilled Nursing Facilities: A Review Of The Literature And Application To A Local Skilled Nursing Home, Hailey Griffin
Undergraduate Honors Capstone Projects
The purpose of this paper may be divided into two parts. The first part was a literature review that sought to determine the most common risk factors for developing a urinary tract infection in nursing homes, as well as to identify evidence-based practice interventions for decreasing UTI rates within that specific patient population. The second part consisted of a case study that sought to apply the principles gathered from the literature review to the UTI logs of a deidentified local nursing home. It was found that indwelling urinary catheters and age are the two most common precipitating risk factors for …
The Levant: Climate Change’S Effects On Domestic And Foreign Security Policy, Mary Mckenna Kump
The Levant: Climate Change’S Effects On Domestic And Foreign Security Policy, Mary Mckenna Kump
Undergraduate Honors Capstone Projects
This project applies a comparative analysis of climate effects on security perspectives in the Levant (Israel, Palestine, Jordan, and Lebanon) with evidence from historical events and modern processes. In other words, how do the effects of climate change threaten states’ core national security interests? What areas of the system are likely to be impacted by climate effects? Researchers project that climate change will affect current and future global conditions, so how does it impact how states perceive the environment in relation to their national security interests? To examine these questions, I have developed a relatively informal cause-and-effect relationship between climate …
Establishment Of A Transgenic Human Angiotensin Converting Enzyme-2 Hamster Infection Model For The Evaluation Of Therapeutics Against Severe Acute Respiratory Syndrome Coronavirus 2, Scott A. Gibson
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
The virus SARS-CoV-2 emerged in late 2019 and has gone on to spread throughout the global population. The virus is still the cause of a healthcare crisis two years after being identified. Viral infection in humans leads to the development of the disease COVID-19. A complex disease that can result in a wide variety of outcomes for infected individuals. In the majority of individuals, COVID-19 will manifest as either an asymptomatic disease state or a mild to moderate disease state that is resolved in approximately one week. In some infected patients COVID-19 will manifest with the rapid onset of severe …
Evaluating Methods For Pathogen Spillover Detection And Forecasting In Desert Bighorn Sheep (Ovis Canadensis Nelsoni), Grete E. Wilson-Henjum
Evaluating Methods For Pathogen Spillover Detection And Forecasting In Desert Bighorn Sheep (Ovis Canadensis Nelsoni), Grete E. Wilson-Henjum
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Managers mitigate the effects of disease on wildlife populations by detecting outbreaks and predicting disease transmission. Bighorn sheep (Ovis canadensis) populations face threat from the introduced pathogen Mycoplasma ovipneumoniae (M. ovipneumoniae). In the eastern Mojave Desert, managers detect pathogen outbreaks in desert bighorn (O. c. nelsoni) through aerial population surveys, which produce irregular and coarse population information. Furthermore, managers model the risk of M. ovipneumoniae transmission amongst desert bighorn populations, however these models assume that desert bighorn space use is unchanging across years. Here, I evaluate methods used by managers to detect disease outbreaks …
Treating Yellow Fever Virus With The Antiviral Bdaa And Effects On The Immune Response In An Animal Model, Abbie Weight
Treating Yellow Fever Virus With The Antiviral Bdaa And Effects On The Immune Response In An Animal Model, Abbie Weight
Student Research Symposium
Yellow fever virus (YFV) is a mosquito-borne virus with a considerable disease burden in South America and Africa and no approved antivirals. BDAA is an experimental antiviral for YFV which inhibits the viral protein NS4B and is effective against YFV in cell culture and a hamster model. Along with directly inhibiting virus replication, treating YFV-infected cells with BDAA increases the detection and response to foreign RNA by the host cell by releasing YFV replication intermediates into the cytoplasm. While this has been shown in cell culture, it is important to understand if this immune effect is relevant to BDAA’s efficacy …
Engineered Production Of Bioactive Polyphenolic O-Glycosides, Jie Ren, Caleb Don Barton, Jixun Zhan
Engineered Production Of Bioactive Polyphenolic O-Glycosides, Jie Ren, Caleb Don Barton, Jixun Zhan
Biological Engineering Faculty Publications
Polyphenolic compounds (such as quercetin and resveratrol) possess potential medicinal values due to their various bioactivities, but poor water solubility hinders their health benefits to humankind. Glycosylation is a well-known post-modification method to biosynthesize natural product glycosides with improved hydrophilicity. Glycosylation has profound effects on decreasing toxicity, increasing bioavailability and stability, together with changing bioactivity of polyphenolic compounds. Therefore, polyphenolic glycosides can be used as food additives, therapeutics, and nutraceuticals. Engineered biosynthesis provides an environmentally friendly and cost-effective approach to generate polyphenolic glycosides through the use of various glycosyltransferases (GTs) and sugar biosynthetic enzymes. GTs transfer the sugar moieties from …
Epidemic Highs And Lows: A Stochastic Diffusion Model For Active Cases, Luis F. Gordillo, Priscilla E. Greenwood, Dana Strong
Epidemic Highs And Lows: A Stochastic Diffusion Model For Active Cases, Luis F. Gordillo, Priscilla E. Greenwood, Dana Strong
Mathematics and Statistics Faculty Publications
We derive a stochastic epidemic model for the evolving density of infective individuals in a large population. Data shows main features of a typical epidemic consist of low periods interspersed without breaks of various intensities and duration. In our stochastic differential model, a novel reproductive term combines a factor expressing the recent notion of ‘attenuated Allee effect’ and a capacity factor is controlling the size of the process. Simulation of this model produces sample paths of the stochastic density of infectives, which behave much like long-time Covid-19 case data of recent years. Writing the process as a stochastic diffusion allows …
Affected Family Members' Communicative Management Of Opioid Misuse Stigma: Applying And Rethinking The Stigma Management Communication Typology, Sydney O'Shay, Emily Pasman, Danielle L. Hicks, Suzanne Brown, Elizabeth Aguis, Stella M. Resko
Affected Family Members' Communicative Management Of Opioid Misuse Stigma: Applying And Rethinking The Stigma Management Communication Typology, Sydney O'Shay, Emily Pasman, Danielle L. Hicks, Suzanne Brown, Elizabeth Aguis, Stella M. Resko
Communication Studies and Philosophy Faculty Publications
Opioid misuse is a prevalent health problem in the United States with consequences extending past the person who misuses opioids to affected family members (AFM) through courtesy stigma. The goals of this study were to understand the stigma management communication (SMC) strategies employed by AFMs when they experience courtesy stigma and changes in strategies used over time. The findings from interviews with 34 AFMs suggest the SMC strategies they employ range from those that indicate acceptance of stigma and avoidance of stigma situations to strategies where AFMs actively challenge opioid misuse stigma. However, strategy use depended on the social context …
Affected Family Members’ Communicative Management Of Opioid Misuse Stigma: Applying And Rethinking The Stigma Management Communication Typology, Sydney O'Shay, Emily Pasman, Danielle L. Hicks, Suzanne Brown, Elizabeth Aguis, Stella M. Resko
Affected Family Members’ Communicative Management Of Opioid Misuse Stigma: Applying And Rethinking The Stigma Management Communication Typology, Sydney O'Shay, Emily Pasman, Danielle L. Hicks, Suzanne Brown, Elizabeth Aguis, Stella M. Resko
Publications
Opioid misuse is a prevalent health problem in the United States with consequences extending past the person who misuses opioids to affected family members (AFM) through courtesy stigma. The goals of this study were to understand the stigma management communication (SMC) strategies employed by AFMs when they experience courtesy stigma and changes in strategies used over time. The findings from interviews with 34 AFMs suggest the SMC strategies they employ range from those that indicate acceptance of stigma and avoidance of stigma situations to strategies where AFMs actively challenge opioid misuse stigma. However, strategy use depended on the social context …
Hucopia: An Atlas Of Human Vs. Sars-Cov-2 Interactome And The Comparative Analysis With Other Coronaviridae Family Viruses, Naveen Duhan, Rakesh Kaundal
Hucopia: An Atlas Of Human Vs. Sars-Cov-2 Interactome And The Comparative Analysis With Other Coronaviridae Family Viruses, Naveen Duhan, Rakesh Kaundal
Plants, Soils, and Climate Faculty Publications
SARS-CoV-2, a novel betacoronavirus strain, has caused a pandemic that has claimed the lives of nearly 6.7M people worldwide. Vaccines and medicines are being developed around the world to reduce the disease spread, fatality rates, and control the new variants. Understanding the protein-protein interaction mechanism of SARS-CoV-2 in humans, and their comparison with the previous SARS-CoV and MERS strains, is crucial for these efforts. These interactions might be used to assess vaccination effectiveness, diagnose exposure, and produce effective biotherapeutics. Here, we present the HuCoPIA database, which contains approximately 100,000 protein-protein interactions between humans and three strains (SARS-CoV-2, SARS-CoV, and MERS) …
Factors Affecting Knowledge, Attitude, And Practice Of Covid-19: A Study Among Undergraduate University Students In Bangladesh, Mufti Nadimul Quamar Ahmed, Shamim Al Aziz Lalin, Saeed Ahmad
Factors Affecting Knowledge, Attitude, And Practice Of Covid-19: A Study Among Undergraduate University Students In Bangladesh, Mufti Nadimul Quamar Ahmed, Shamim Al Aziz Lalin, Saeed Ahmad
Sociology and Anthropology Student Research
The global expansion of the COVID-19 outbreak is one of the worst disasters the world has faced in recent decades. This study explored various factors of knowledge, attitude, and practice regarding COVID-19 among Bangladeshi undergraduate university students. In addition, we also look at how COVID-19 based knowledge, attitude, and practice influence each other. Using a random sampling technique and a self-administered structured questionnaire survey, this study collected data from 167 private university students in Bangladesh from 1st October to 30th October 2020. Data were analyzed using descriptive statistics (including frequencies, percentages, and means), binary logistic regression, bivariate regression analysis, and …
Invasive Species Handbook: A Resource For Educators - Grades 3-8, Natalie D'Souza, Marion Murray, Lori R. Spears
Invasive Species Handbook: A Resource For Educators - Grades 3-8, Natalie D'Souza, Marion Murray, Lori R. Spears
All Current Publications
This handbook includes six chapters that discuss invasive species and their environmental, economic, and health impacts. It also reviews pathways of invasive species spread and prevention, monitoring, and control. The handbook is a resource for educators teaching children in grades 3 through 8. Learning objectives, activities, and vocabulary are also included.
Interview With Amanda Derito, Utah State University Special Collections & Archives
Interview With Amanda Derito, Utah State University Special Collections & Archives
Utah State University COVID-19 Oral History Collection
No abstract provided.
Interview With Amy Rasmussen, Utah State University Special Collections & Archives
Interview With Amy Rasmussen, Utah State University Special Collections & Archives
Utah State University COVID-19 Oral History Collection
No abstract provided.
Interview With Kieth Roper, Utah State University Special Collections & Archives
Interview With Kieth Roper, Utah State University Special Collections & Archives
Utah State University COVID-19 Oral History Collection
No abstract provided.
Interview With Katie Trepanier, Utah State University Special Collections & Archives
Interview With Katie Trepanier, Utah State University Special Collections & Archives
Utah State University COVID-19 Oral History Collection
No abstract provided.
Interview With Valerie Crowley, Utah State University Special Collections & Archives
Interview With Valerie Crowley, Utah State University Special Collections & Archives
Utah State University COVID-19 Oral History Collection
No abstract provided.
Low Resource Assay For Tracking Sars-Cov-2 In Wastewater, Julissa Van Renselaar
Low Resource Assay For Tracking Sars-Cov-2 In Wastewater, Julissa Van Renselaar
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Wastewater based epidemiology (WBE) allows for the tracking of nucleic acid of SARS-CoV-2 in wastewater which gives the opportunity for the public and government officials to be informed about the infectivity of the virus in a community. Advances have been made in WBE that have allowed for higher performance, lower resource use, and faster turnaround time. An adapted concentration method of spin column direct extraction has yielded a proxy virus recovery of 83%, consumable cost of $2.01 per sample, and a turnaround time of 0.33 hour/sample. Other concentration methods have lower proxy virus recoveries, comparable cost, and comparable turnaround time. …
Bugs, Bullets And Birds: Factors Affecting The Health And Survival Of Ferruginous Hawk Nestlings In The Intermountain West, Ellis A. Juhlin
Bugs, Bullets And Birds: Factors Affecting The Health And Survival Of Ferruginous Hawk Nestlings In The Intermountain West, Ellis A. Juhlin
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Ferruginous Hawks are a bird of prey species that nest in sagebrush steppe and grassland habitat. These birds are threatened by habitat loss and fragmentation from urbanization, rural development, oil and natural gas extraction, habitat treatment projects, and wildfires, and experiencing widespread population declines across their breeding range. Because of this, Ferruginous Hawks (FEHAs) have been deemed a Species of Greatest Conservation Need by state management agencies in Utah, Idaho, Wyoming and Nevada. The health and survival of Ferruginous Hawk (FEHA) nestlings is crucial to long-term population viability. Understanding the threats these birds are facing as nestlings can provide valuable …
Insecticide Susceptibility And Resistance Detection In Phlebotomus Argentipes Sandflies (Diptera: Psychodidae: Phlebotominae), Shawna M. Hennings
Insecticide Susceptibility And Resistance Detection In Phlebotomus Argentipes Sandflies (Diptera: Psychodidae: Phlebotominae), Shawna M. Hennings
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Leishmaniasis is an understudied disease found predominantly in high heat and humidity areas. The disease is transmitted by sandflies which are blood-feeding, biting insects. There is currently no known vaccine for any form of leishmaniasis and treatment imposes a significant economic impact on already poor and marginalized populations, as well as severe, lingering side effects for afflicted individuals. Annually, there are millions of people around the world afflicted with a form of Leishmaniasis that is transmitted by species of sandflies. The primary sandfly population control method for over half a century has been indoor residual spraying using insecticides. The selective …
Understanding The Behavior, Challenges, And Privacy Risks In Digital Technology Use By Nursing Professionals, Ankit Shrestha, Danielle M. Graham, Prakriti Dumaru, Rizu Paudel, Kristin A. Searle, Mahdi Nasrullah Al-Ameen
Understanding The Behavior, Challenges, And Privacy Risks In Digital Technology Use By Nursing Professionals, Ankit Shrestha, Danielle M. Graham, Prakriti Dumaru, Rizu Paudel, Kristin A. Searle, Mahdi Nasrullah Al-Ameen
Computer Science Student Research
With the growing adoption of digital technology in healthcare organizations, it is important to understand nursing professionals’ behavior and challenges, and the corresponding privacy implications around digital technology use. To this end, we conducted semi-structured interviews with 21 participants (16 nursing professionals, and five nursing faculties) in the USA. In our study with nursing professionals, we explored how they used digital technology and protected sensitive health data at their workplace. We investigated their understanding of privacy breaches and possible consequences, the challenges they encountered to maintaining privacy, and their workarounds to deal with such issues. We looked into the support …
Development And Characterization Of Type I Interferon Receptor Knockout Sheep: A Model For Viral Immunology And Reproductive Signaling, Christopher J. Davies, Zhiqiang Fan, Kira P. Morgado, Ying Liu, Misha Regouski, Qinggang Meng, Aaron J. Thomas, Sang-Im Yun, Byung-Hak Song, Jordan C. Frank, Iuri V. Perisse, Arnaud Van Wettere, Young-Min Lee, Irina A. Polejaeva
Development And Characterization Of Type I Interferon Receptor Knockout Sheep: A Model For Viral Immunology And Reproductive Signaling, Christopher J. Davies, Zhiqiang Fan, Kira P. Morgado, Ying Liu, Misha Regouski, Qinggang Meng, Aaron J. Thomas, Sang-Im Yun, Byung-Hak Song, Jordan C. Frank, Iuri V. Perisse, Arnaud Van Wettere, Young-Min Lee, Irina A. Polejaeva
Animal, Dairy, and Veterinary Science Faculty Publications
Type I interferons (IFNs) initiate immune responses to viral infections. Their effects are mediated by the type I IFN receptor, IFNAR, comprised of two subunits: IFNAR1 and IFNAR2. One or both chains of the sheep IFNAR were disrupted in fetal fibroblast lines using CRISPR/Cas9 and 12 lambs were produced by somatic cell nuclear transfer (SCNT). Quantitative reverse transcription-polymerase chain reaction for IFN-stimulated gene expression showed that IFNAR deficient sheep fail to respond to IFN-alpha. Furthermore, fibroblast cells from an IFNAR2−/− fetus supported significantly higher levels of Zika virus (ZIKV) replication than wild-type fetal fibroblast cells. Although many lambs have …
Developing Confidence And Interest In Teaching Relevant Mathematical Modeling Lessons, Jacy Beck
Developing Confidence And Interest In Teaching Relevant Mathematical Modeling Lessons, Jacy Beck
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
What is mathematical modeling and how can inservice and pre-service teachers develop the skills and competencies necessary to increase confidence and interest in teaching relevant mathematical modeling lessons? Mathematical modeling is “the process of choosing and using appropriate mathematics and statistics to analyze empirical situations, to understand them better, and to improve decisions” (CSSM, 2010, p. 72). By providing students with an opportunity to engage in relevant mathematical modeling prompts, we provide them with transferable skills and knowledge. The aim of this paper will be to provide insight into the relevance of teaching mathematical modeling, provide resources for integrating modeling …
Modeling A Pandemic: Investigating Student Learning About Disease Spread In The Context Of Agent-Based Modeling, Siyu Wu
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
The COVID-19 pandemic has highlighted a need for students to learn about public health issues, including the transmission of disease and methods for the prevention of epidemics. This study presents data from a project focused on developing computational microworlds to help middle school students learn about these topics. The microworld is designed to help students model and test their ideas about how a disease spreads through a population and how an epidemic can be prevented. I employed a lab-based case study approach to conduct one-on-one 1.5-hour interviews through Zoom with four middle-school students (ages 12-14). During the interview, the student …
Pesticide-Leaf Interactions And Their Implications For Pesticide Fate Modeling, Ashlie Kinross
Pesticide-Leaf Interactions And Their Implications For Pesticide Fate Modeling, Ashlie Kinross
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
The work described here provides measured data to improve the understanding of the interaction between a pesticide and leaf surface after application. Two methods were developed, one using a newly introduced instrument, for the extraction of pesticides from leaves. This is required to measure the concentration of pesticide in the leaves. Using one of the developed extraction methods, measurements were made to determine how a pesticide equilibrates between a leaf and the air above it. These measurements were incorporated into a pesticide fate model that predicts how a pesticide moves through the environment after application to an agricultural field. The …
Pandemics & People: Designing A Virtual Epidemic Event For Immersive, Connected, And Playful Participation In An Infectious Disease Outbreak, Deborah Fields, Amanda Strawhacker, Michael Giang, Yasmin Kafai, Colby Tofel-Grehl, Tyler Hansen, Jen Sun, Mark Dinan
Pandemics & People: Designing A Virtual Epidemic Event For Immersive, Connected, And Playful Participation In An Infectious Disease Outbreak, Deborah Fields, Amanda Strawhacker, Michael Giang, Yasmin Kafai, Colby Tofel-Grehl, Tyler Hansen, Jen Sun, Mark Dinan
Teacher Education and Leadership Faculty Publications
Researchers and educators have identified an urgent need for more rigorous teaching and learning about epidemiology topics and practices, such as engaging in behaviors that prevent the spread of viral disease such as COVID-19. Responding to this need, we designed a virtual epidemic as a special event hosted in a virtual world. In this paper we share the strategic, tactical, and detailed design of the SPIKEY-20 virtual epidemic and data that reflects back on the design in terms of player participation. Reflecting on the design, we ask: What kinds of players participated in the SPIKEY-20 virtual epidemic? How did players …