Digital Commons Network^™

Structure Based Inhibitor Discovery Targeting Multiple Β-Lactamases Involved In Antibiotic Resistance, Afroza Akhtar

USF Tampa Graduate Theses and Dissertations

Emergence of antibiotic resistance severely threatens the existing medication and prevention facilities against an over increasing range of infections caused by a wide range of microbes. Specifically, treatment of Gram-negative bacterial infection is getting more problematic due to their resilience against β-lactam antibiotics: the most commonly prescribed antibiotics in clinical settings. Production of β-lactamases is the most prevalent mechanism utilized by various Gram-negative pathogens to become resistant to the β-lactam antibiotics e.g, penicillins, cephalosporins, carbapenems and monobactams. These enzymes mediate their function through hydrolyzing the core β-lactam ring present in all β-lactam antibiotics which causes opening of the ring and …

Ay 2019/2020 Fs Meeting Minutes, 2020-02-26, Faculty Senate

Faculty Senate Archives

No abstract provided.

Crow's Nest, February 24, 2020, Crow's Nest Staff

Crow's Nest

The February 24, 2020, issue of the Crow's Nest.

Algorithms To Profile Driver Behavior From Zero-Permission Embedded Sensors, Bharti Goel

USF Tampa Graduate Theses and Dissertations

In this dissertation, we design algorithms to profile driver behavior from zero-permission sensors embedded in modern smartphones and wearables. These sensors are typically the accelerometer, gyroscope, magnetometer, pressure sensor and a few more than are now available in most modern smartphones and wearables. In order to profile driving behavior, we devised algorithms for detecting distraction while driving due to the use of modern-day smartphones (e.g., calling, texting and reading while driving) in real-time.

To do so, we conduct an experiment with 16 subjects on a realistic driving simulator, where each subject, where each subject carries a smartphone and a wearable …

Differential Reinforcement Without Extinction: An Assessment Of Sensitivity To And Effects Of Reinforcer Parameter Manipulations, Hannah Lynn Macnaul

USF Tampa Graduate Theses and Dissertations

Individuals with an Autism Spectrum Disorder (ASD) often engage in problem behavior (e.g., aggression, property destruction, self-injurious behavior; Horner, Carr, Strain et al., 2002) that may limit access to traditional social and education settings, impact their health, and pose a risk to their safety and the safety of others. One of the most common interventions used to treat problem behavior is differential reinforcement of alternative behavior (DRA; Cooper, Heron, & Heward, 2007), which are often used in combination with other interventions such as extinction (Shirley, Iwata, Kahng, Mazaleski, & Lerman, 1997). However, implementation of extinction may pose an ethical dilemma …

Assessment Of Land Cover Change In St. Martin’S Marsh Aquatic Preserve, Florida, Usa, Katie Wagner

USF Tampa Graduate Theses and Dissertations

St. Martin’s Marsh Aquatic Preserve (SMMAP) is a 28,461 acre (115.18 km2) preserve located on the coast of Citrus County, Florida, USA. There has been no published research that focused on coastal change on this unique coast. This thesis research focuses on coastal land cover change that has occurred within the preserve from 1988 to 2018. Multitemporal Landsat images were classified using a support vector machine (SVM) classification, while changes in vegetation were evaluated using the normalized difference vegetation index (NDVI). Field research was conducted to examine nineteen sites for classification training and test data and notes on habitat composition. …

Roots In Antiquity: A Comparative Study Of Two Cultures, Lara Younes Freajah

USF Tampa Graduate Theses and Dissertations

This study was conducted with the goal to provide an in-depth analysis of the analogous qualities of two very distinct yet similar cultures: the Arab and Sarakatsan cultures, with a particular focus on personal matters that deal with family and kinship. Despite the difference in religions, both groups demonstrate a substantive set of similar traits especially in terms of the interactions, dynamics, and functionality of family relations in addition to the highly-esteemed values that dictate everyday conduct. As a first-generation Arab Muslim who immigrated to the United States, I use the culture in which I am entrenched as a basis …

A Plan For Progress, Preservation, And Presentation At The Safety Harbor Museum And Cultural Center, Amanda L. Ward

USF Tampa Graduate Theses and Dissertations

There are numerous ways in which heritage can be managed and presented to the public, such as: physical museums, virtual museums, tours of historic homes, and archaeological parks. For this project, I participated in and observed heritage preservation management under a unique partnership of the City of Safety Harbor recreation department and the Safety Harbor Museum Board in Safety Harbor, Florida. My internship was with the Safety Harbor Museum and Cultural Center, primarily under the direction of Shannon Schafer and Christine McWilliams. My initial focus was assisting these two groups with projects specific to the needs of the museum. I …

Legitimizing Violence: Functional Similarities Of The Religious And The Secular Violence, Tahir Topal

USF Tampa Graduate Theses and Dissertations

As a consequence of the separation between religion and politics, known as secularism, the discussion about violence has also been divided into two main categories –Religious Violence and Non-Religious Violence– in the modern Western academia. The tendency of the leading scholarly work in the discourse of "religious violence" is that "religion" is inclined to be violent more than secular institutions for several reasons. Therefore, the state's violence, as being secular, steps in to bring peace. And the foundational cause of the theories relies heavily on the essential differences of "religion" and the secular. With counter-arguments, William T. Cavanaugh and Talal …

Global Karst Springs Hydrograph Dataset For Research And Management Of The World’S Fastest-Flowing Groundwater, Tunde Olarinoye, Tom Gleeson, Vera Marx

KIP Articles

Karst aquifers provide drinking water for 10% of the world’s population, support agriculture, groundwater-dependent activities, and ecosystems. These aquifers are characterised by complex groundwater-flow systems, hence, they are extremely vulnerable and protecting them requires an in-depth understanding of the systems. Poor data accessibility has limited advances in karst research and realistic representation of karst processes in large-scale hydrological studies. In this study, we present World Karst Spring hydrograph (WoKaS) database, a community-wide effort to improve data accessibility. WoKaS is the first global karst springs discharge database with over 400 spring observations collected from articles, hydrological databases and researchers. The dataset’s …

The Weekly Challenger, February 20, 2020, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The February 20, 2020, issue of The Weekly Challenger.

Orders Of Normativity: Nietzsche, Science And Agency, Shane C. Callahan

USF Tampa Graduate Theses and Dissertations

In this dissertation I set out to address the “scope problem” in Nietzsche scholarship. In the secondary literature, the scope problem is characterized as a problem for Nietzsche, who seems deeply skeptical about nearly every item of his inherited western metaphysical toolkit. If his skepticism about western metaphysics penetrates all dimensions of his thought, how can he motivate a reader to also reject western metaphysics without himself committing to some of it? I stipulate that answering the scope problem means explicating what Nietzsche views as the general source of normativity—it is there that we can understand the resources Nietzsche is …

The Effects Of Socioscientific Issues On Informal Reasoning And The Transference To Controversial Issues In A Social Studies Context, Thomas J. Dolan

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to determine if informal reasoning skills associated with socioscientific issues (SSI) transferred to controversial issues in a social studies context. The principal researcher developed three controversial issues derived from social studies education to create social studies context issues (SSCI). This acronym has been termed by the principal researcher, as controversial issues in social studies have not been evaluated beyond the social studies classroom. Twenty-one, fifth grade students participated in this three-month study, which featured three specific SSI units (A Need for Speed? – speed limit reduction, Roller Coaster Ban – preventing injuries to children, …

Villains Or Vermin? The Differential Effects Of Discrimination And Dehumanization On Immigrant Cardiovascular Responses, Mona El-Hout

USF Tampa Graduate Theses and Dissertations

Immigration has been pushed to the forefront of a national political debate, and immigrants are commonly portrayed as villains and vermin looking to invade and infest Western nations. These negative portrayals of immigrants may have negative implications for immigrant health outcomes. Among other negative health outcomes, studies have found that immigrant cardiovascular disease rates increase with time spent in the U.S. This phenomenon of decreasing immigrant health with extended U.S. residency has been labeled “the immigrant health paradox”, and discrimination has often been posited as a possible explanatory factor. In addition to discrimination, immigrants are often the targets of dehumanization, …

Isotope-Based Methods For Evaluating Fish Trophic Geographies, Julie L. Vecchio

USF Tampa Graduate Theses and Dissertations

Data on the movement and diets of fish during a variety of life stages are important inputs to fisheries stock assessments and marine ecosystem models. Stable isotopes may provide previously inaccessible information on movement and diet of a variety of managed and forage fish species. Here I used several novel means of interpretation for stable isotope data to infer diets and movements of several important fisheries species over both short (weeks to months) and long (lifetime) timescales. To calculate a constant partitioning offset (CPO) between the δ¹⁵N of muscle and of liver tissue, I conducted a literature search …

Does Gestational Diabetes Mellitus Increases The Risk Of Preeclampsia Among Primigravid Women?, Astha Kakkad

USF Tampa Graduate Theses and Dissertations

Gestational diabetes mellitus (GDM) and preeclampsia are serious complications of pregnancy which are associated with both short- and long-term adverse health outcomes for the mother as well as the fetus. The increase in prevalence of these conditions has become a major public health concern. The purpose of this study is to examine the association and risk imposed by GDM for preeclampsia in primigravid women. This descriptive study was conducted using data retrieved from the electronic medical records of a large integrated health system in Florida. The data for this analysis included pregnancy records for patients at least 18 years of …

The Concept Of Freedom In American Literature At The Dawn Of The Nation, Mykhailo Pylynskyi

USF Tampa Graduate Theses and Dissertations

This thesis analyzes American literature dedicated to the American Revolutionary War (1775-1783) and the events which led to it. The overarching goal of the analysis is to lay out a coherent account of the concept of freedom in American literature of that time period. To reach this goal I will use The Second Treatise of Government by John Locke as a main philosophical text, which outlines the key elements of political freedom. As the main literature pieces of the selected time period, Common Sense by Thomas Paine and The Liberty Song were chosen. I will also use multiple songs by …

Crow's Nest, February 17, 2020, Crow's Nest Staff

Crow's Nest

The February 17, 2020, issue of the Crow's Nest.

Microfluidically Reconfigurable Millimeter-Wave Switches, Antenna Arrays And Filters With Fast-Actuation Using Movable Metallized Plates And Integrated Actuation, Enrique J. Gonzalez Carvajal

USF Tampa Graduate Theses and Dissertations

Microfluidic reconfiguration of microwave devices has emerged as a potentially attractive alternative to integrated semiconductor (ICs/MMICs) and microelectromechanical systems (MEMS) based technologies. On the one hand, MMICs suffer from low power handling capabilities, high IL, non-linear effects, and elevated costs; on the other hand, MEMS are limited by their complex packaging requirements, and relatively low reliability from stiction-based effects. However, microfluidic reconfiguration provides low insertion loss (IL) due to its mechanical nature and it is not limited by power saturation effects. These attributes are especially valuable for applications at mm-waves, potentially reducing costs and increasing power efficiency capabilities. Microfluidic reconfiguration …

Are We Still Bowling Alone? Lessons From The American Democracy Project, George Mehaffy

Bay to Bay Symposium

No abstract provided.

The Weekly Challenger, February 13, 2020, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The February 13, 2020, issue of The Weekly Challenger.

Immunogenic Proteins Against Clostridium Difficile, Xingmin Sun

USF Patents

Described are immunogenic proteins against Clostridium difficile. Also described are compositions comprising the immunogenic proteins. Further described are methods of preventing or treating a Clostridium difficile infection in a subject in need thereof.

Chronic Pah Exposures And Associated Declines In Fish Health Indices Observed For Ten Grouper Species In The Gulf Of Mexico, Erin Pulster, Adolfo Gracia, Maickel Armenteros, Brigid Carr, Justin Mrowicki, Steven Murawski

C-IMAGE Publications

Ten grouper species grouper (n = 584) were collected throughout the Gulf of Mexico (GoM) from 2011 through 2017 to provide information on hepatobiliary polycyclic aromatic hydrocarbon (PAH) concentrations in the aftermath of the Deepwater Horizon (DWH) oil spill. Liver and bile samples were analyzed for PAHs and their metabolites using triple quadrupole mass spectrometry (GC/MS/MS) and high-performance liquid chromatography with fluorescence detection (HPLC-F), respectively. Data were compared among species and sub-regions of the GoM to understand spatiotemporal exposure dynamics in these economically and ecologically important species. Significant differences in the composition and concentrations of PAHs were detected spatially, …

Crow's Nest, February 10, 2020, Crow's Nest Staff

Crow's Nest

The February 10, 2020, issue of the Crow's Nest.

Threat-Induced Alterations In Cognition And Associations With Disinhibited Behavior, Julia B. Mcdonald

USF Tampa Graduate Theses and Dissertations

When a threat is detected, brain networks associated with threat processing are activated while other processes are deprioritized. While this resource allocation is adaptive, it makes it especially difficult to effortfully direct thoughts, emotions, and behaviors (use cognitive control) during situations of high stress. Further, this threat response is most efficient in response to short-term or predictable stressors (“threats”) but loses its efficiency for ambiguous or unpredictable threats. Despite research that suggests that threat induces psychological states associated with breakdown in cognitive control processes, no study has directly examined how predictability of threat impacts neurocognitive indicators of cognitive control processes. …

Exploration Of Factors Associated With Perceptions Of Community Safety Among Youth In Hillsborough County, Florida: A Convergent Parallel Mixed-Methods Approach, Yingwei Yang

USF Tampa Graduate Theses and Dissertations

Introduction: Youth perceived safety is not only linked to crime and violence in a neighborhood but is also associated with health risk behaviors and certain neighborhood characteristics. The purpose of this mixed-methods study was to measure the co-occurring effects of individual and community risk factors by conducting a secondary data analysis using structural equation modeling (SEM) and to explore reasons for youth feeling safe/unsafe in their community using photovoice methodology.

Methods: Syndemic theory/model served as the theoretical framework to guide this mixed-methods study with a convergent parallel design. The quantitative strand (first manuscript) utilized an existing dataset collected from middle …

Pathways To Leadership: A Qualitative Study Of Women In Higher Education, Kymia Love Jackson

USF Tampa Graduate Theses and Dissertations

Women earn degrees at a higher rate than men, yet they are underrepresented in leadership positions in general and more specifically, in executive leadership positions in the areas of finance, operations, and administration (FOA) in higher education. This qualitative study explored the journeys of women in executive leadership positions in finance, operations, and administration at four-year, public colleges or universities. The research question that guided this study was: How do women describe their experiences of securing, transitioning into, and advancing within executive leadership positions in FOA in higher education? Document and content analysis, demographic questionnaire, observations, interviews, and reflection were …

Identifying Barriers And Facilitators To Improve Hepatitis C Virus Screening, Linh M. Duong

USF Tampa Graduate Theses and Dissertations

Background: Birth cohort hepatitis C Virus (HCV) screening recommendations were issued by the Centers for Disease Control and Prevention (CDC) and United States Preventive Services Task Force (USPSTF) in 2012 and 2013, respectively. Despite this, studies have reported low HCV screening rates. Currently, the prevalence of HCV screening rates nationally is unknown and there are no in-depth studies that have evaluated the barriers or facilitators of HCV screening. Our study aimed to fill this gap by 1) conducting a systematic literature review to assess the national HCV screening prevalence, 2) evaluating temporal trends in HCV screening using a large academic …

Evaluation Of Optimal Technique For Left Breast Irradiation, Amitpal Singh Saini

USF Tampa Graduate Theses and Dissertations

Numerous studies have indicated that radiation therapy reduces the risk of the local recurrence of breast cancer in several cases and that it has increased the overall survival rate. Although radiation therapy is beneficial for the treatment of breast cancer, it is known to increase the risk of both radiation toxicity and secondary breast cancer. In left-sided breast cancer, radiation therapy treatment often leads to the heart and its components—such as the left ventricle and left anterior descending artery—being exposed to high doses of radiation because of the proximity of the heart to the left breast, resulting in cardiac complications …

New Evidence For An Early Settlement Of The Yucatán Peninsula, Mexico: The Chan Hol 3 Woman And Her Meaning For The Peopling Of The Americas, Wolfgang Stinnesbeck, Samuel R. Rennie, Jerónimo Avilés Olguín

KIP Articles

Human presence on the Yucatán Peninsula reaches back to the Late Pleistocene. Osteological evidence comes from submerged caves and sinkholes (cenotes) near Tulum in the Mexican state of Quintana Roo. Here we report on a new skeleton discovered by us in the Chan Hol underwater cave, dating to a minimum age of 9.9±0.1 ky BP based on 230Th/U-dating of flowstone overlying and encrusting human phalanges. This is the third Paleoindian human skeleton with mesocephalic cranial characteristics documented by us in the cave, of which a male individual named Chan Hol 2 described recently is one of the oldest human skeletons …