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The Weekly Challenger, November 26, 2020, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The November 26, 2020, issue of The Weekly Challenger.

Cognition In Health And Disease: Two Mouse Model Studies, Heather Lynn Mahoney

USF Tampa Graduate Theses and Dissertations

Cognitive and circadian dysfunction are common aspects of neuropsychiatric disease that are often overlooked in disease models and treatment strategies. In this work, we first evaluated the potential for cognitive enhancement in healthy adult mice by targeting a kinase involved in regulation of the molecular circadian clock. We then developed and characterized a model of neuropsychiatric disease that could present a target for rescuing circadian and cognitive deficits using this treatment.

Time-of-day effects have been noted in a wide variety of cognitive behavioral tests, and perturbation of circadian rhythms impairs hippocampus-dependent learning and memory. We first asked whether casein kinase …

Crow's Nest, November 23, 2020, Crow's Nest Staff

Crow's Nest

The November 23, 2020, issue of the Crow's Nest.

Micro-Architectural Countermeasures For Control Flow And Misspeculation Based Software Attacks, Love Kumar Sah

USF Tampa Graduate Theses and Dissertations

Embedded system applications in diverse sectors such as transportation, healthcare, homeautomation, etc., have been gathering, processing, and transporting data using embedded computers connected to vast networks. As the usage of these embedded devices in daily life is increasing exponentially, security of these devices is a growing concern amongst the users. An alarming rise in recent cyber-attacks has deepened such concern. In the recent past, software-based attacks are more sophisticated and larger in scale than previously known. An embedded processor depends on a compiler to use the architecture efficiently. The compiler generates object code to efficiently utilize the micro-architecture for storage …

Article, Tampa Bay Was Built On Native Land, So Say ‘Ysaco Niquosonihaue Nimantela’ This Thanksgiving, November 20, 2020, Thomas Hallock

Creekshed: City Wilds

An article by Thomas Hallock about the original Indigenous inhabitants of St. Petersburg, Florida.

Dendriplex - Cyclodextrin Conjugates For Gene Delivery To Retina, Durga Deepak Puro

USF Tampa Graduate Theses and Dissertations

Gene therapy holds promise for treating a wide range of diseases including cancer and several other polygenic and monogenic disorder arising in different organs. Due to its immune privilege nature, eye is an ideal organ for gene therapy,as various visual pathologies arise from gene defect and can lead to partial or complete vision loss. The last decade, several nanoparticles have been developed and tested for their transfection efficiency in vitro and in vivo. Among them, dendrimers with small size, good physicochemical properties and endosomal escape activity have shown high transfection efficiency in various cell lines. In an attempt to further …

Stygobitic Crustaceans In An Anchialine Cave With An Archeological Heritage At Vodeni Rat (Island Of Sveti Klement, Hvar, Croatia), Alessandro Montanari, Nicolas Cerveau, Barbara Fiasca, Jean-François Flot, Diana Galassi, Maurizio Mainiero, David Mcgee, Tadeusz Namiotko, Stefano Recanatini, Fabio Stoch

International Journal of Speleology

A group of four amphoras found in the anchialine cave of Vodeni Rat in the Croatian island of Sveti Klement, on a rocky ledge at 24 m water depth, indicates that a freshwater source was exploited at the bottom of this karstic pit by islanders and/or passing-by sailors from the late Roman Republican Period to the Early Medieval Period. In other words, prior to the 4^th–7^th century CE, Vodeni Rat was not an anchialine cave but a Pleistocene karstic pit with a freshwater pool at the bottom. Seawater started to infiltrate this cavity via newly opened fissures …

Compounds For The Treatment Of Neurodegenerative Diseases, Jianfeng Cai, Chuanhai Cao

USF Patents

Disclosed herein are compounds for the treatment of neurodegenerative diseases and compositions comprising the same.

Data-Driven Modeling Of The Causes And Effects Of Interneuronal Dysfunction In Alzheimer’S Disease And Dravet Syndrome, Carlos Perez

USF Tampa Graduate Theses and Dissertations

One of the defining features of Alzheimer’s disease (AD) is the increased cleavage of the amyloid precursor protein (APP), causing abnormally high levels of the aggregation form of amyloid beta (Aβ ). Many studies have shown that both AD patients and AD mice models exhibit abnormal network activity, including hypersynchronous excitatory neuron behavior, altered brain rhythms, and in some instances epileptic seizures when exposed to high levels of Aβ In particular, strong experimental evidence suggests that it is the small globular amyloid oligomers (gOs) and curvilinear fibrils (CFs) rather than the more stable, late stage rigid fibrils (RFs) that cause …

Counseling Clients With Traumatic Brain Injury: Exploring Counselors’ Perceived Knowledge, Comfort, And Self-Awareness, Michelle Bradham-Cousar

USF Tampa Graduate Theses and Dissertations

The number of traumatic brain injury (TBI) diagnoses continues to rise each year. Counseling is a critical factor in TBI treatment, and although numerous studies have investigated TBI outcomes, a paucity of researchers have studied professional counselors’ knowledge, comfort, and self-awareness when working with TBI clients. Due to the diversity of counselor caseloads, it is likely that counselors will serve clients with a dual diagnosis that includes TBI. These dual diagnoses include depression, posttraumatic stress disorder, anxiety, psychosis, or another neurocognitive disorder. The purpose of this study was to explore counselors’ knowledge, comfort, and self-awareness when working with individuals with …

Crow's Nest, November 16, 2020, Crow's Nest Staff

Crow's Nest

The November 16, 2020, issue of the Crow's Nest.

Quantifying The Impact Of Chronic Stress On Racial Disparities In Cardiovascular Disease, Nnadozie Emechebe

USF Tampa Graduate Theses and Dissertations

Background: Despite declining mortality in cardiovascular diseases (CVD), racial disparities between non-Hispanic Blacks (NHB) and to non-Hispanic Whites (NHW) persist. Although the prevalence of traditional risk factors of CVD such as hypertension, is higher in NHB compared to NHW, adjusting for this difference does not eliminate the disparity completely. This suggests other factors might explain the persisting disparities. Thus, the purpose of this dissertation is to quantify the impact of chronic stress in explaining the racial disparities in cardiovascular diseases (CVD). This dissertation contains three studies that addressed the following Specific Aims: Specific aims: 1) To create and assess the …

Evaluating The Effects Of Peer Competition On Physical Activity During School Recess, Heather M. Zerger

USF Tampa Graduate Theses and Dissertations

With an increase in childhood obesity, engagement in regular physical activity is an important health-related behavior. In addition to being overweight or obese, a lack of physical activity can lead to other serious health risks. With children spending a majority of their weekdays at school, this environment should be used to promote physical activity. The purpose of the current study was to evaluate the effects of peer competition and feedback on children’s step counts. During baseline, participants wore a sealed pedometer during recess and physical education (PE). During intervention, participants with higher step counts were paired with participants with lower …

Experimental Investigation Of Liquid Height Estimation And Simulation Verification Of Bolt Tension Quantification Using Surface Acoustic Waves, Hani Alhazmi

USF Tampa Graduate Theses and Dissertations

In this dissertation, two separate applications that are related to surface acoustic waves in a solid media are presented. The first study concerns simulating and validating an experimentally study for quantifying the bolt tension in the bolted joints using the surface acoustic wave. The second study experimentally investigates measuring the level of a liquid existing on a solid surface via surface acoustic waves and exploring the effect of liquid existence on the propagation of surface acoustic waves over the solid surface.

Quantifying bolt tension and ensuring that bolts are appropriately tightened for large-scale civil infrastructures are crucial. This study investigates …

Hearing Aid Acclimatization In The Context Of Central Gain Mechanisms, Peter J. Hutchison

USF Tampa Graduate Theses and Dissertations

The primary goals of this dissertation were to 1) identify markers of central gain in the auditory system following short-term acoustic attenuation via earplugging and acoustic enhancement via sound generators, and 2) determine if acoustic enhancement is effective in modulating central gain in older adults with age-related hearing loss, and if so, to what extent. Additionally, a further goal of this dissertation was to explore the possibility that central gain is related hearing aid acclimatization. The results described in Chapter 2 are further evidence that altering acoustic input to the peripheral auditory system modulates central auditory plasticity and is evident …

Asian Male Stereotypes: An Investigation Of Current Beliefs About Asian Males And Stereotypes Perpetuated By U.S. Modern Cinema, Noelle Knopp

USF Tampa Graduate Theses and Dissertations

This is a triangulated two-part study with a quasi-experiment design. Study Part 1 performed a textual analysis supported by the theory of framing on the films Crazy Rich Asians, To All the Boys I’ve Loved Before, Always Be My Maybe, and To All the Boys: P.S. I Still Love You to find commonalities among portrayals of prominent East Asian male characters. Using Wong et. al’s findings of common perceived stereotypes by Asian American males, the author used the six traits defined by Wong et. al as a base to see if the films corresponded to or deviated from the stereotypes …

Isolation Of Specific Phospholipids From Nannochloropsis Oculata Microalga For Cosmetic Applications, Ahmet Yener Manisali

USF Tampa Graduate Theses and Dissertations

Algae, photosynthetic aquatic organisms, have recently caught the attention of the food, cosmetic, pharmaceutical, and nutraceutical industries due to the variety of natural compounds in their cellular bodies such as carbohydrates, lipids, and proteins. Specifically, microalgae-derived natural compounds such as phospholipids are extensively utilized in cosmetics as part of liposome formers, emulsifiers, solubilizers, and wetting agents. Although phospholipids are currently extracted from food sources, this practice raises sustainability concerns. Hence, growing microalgae on the provision of macronutrients such as nitrates and phosphates will serve as a more sustainable source of the several specific phospholipids such as phosphatidylcholine (PC), phosphatidyl-ethanolamine (PE), …

Circadian Rhythms And The Embodiment Of Social Zeitgebers: Linking The Bio And Social, Tiffany R. Moore

USF Tampa Graduate Theses and Dissertations

Virtually all biological processes are under direct or indirect control of the circadian system. Chronic disruption of circadian rhythms, termed chronodisruption, is linked to increased risk for adverse health outcomes such as cancer, depression, and cardiometabolic disease. Circadian rhythms are highly sensitive to sociocultural contexts. As a result, circadian rhythms provide a valuable entryway to explore issues of embodiment. Here, embodiment refers to processes through which social experiences ‘get under the skin’ to become biological and manifest in health. To better understand what proximate social factors influence chronodisruption, this study assessed chronodisruption and social zeitgebers among a population of 15 …

Corporate Brand Impact On Sales / Revenue Per Share, Brad A. Puckey

USF Tampa Graduate Theses and Dissertations

The purpose of this dissertation is to identify the linkage between the corporate brand and sales / revenue per share growth. Utilizing a unique database, the CoreBrand® Index, this study is a quantitative analysis of the interaction between the corporate brand and financial data. A relationship between corporate brand and financial data has been suspected by practitioners; however, it has never been proven. For the first time, quantitative analysis is conducted in this dissertation using this unique dataset.

This study is intended to help those responsible for managing corporate brands to better understand their impacts and benefits. The more that …

Modeling Early Life: Ontogenetic Growth And Behavior Affect Population Connectivity In Gulf Of Mexico Marine Fish, Kelly Vasbinder

USF Tampa Graduate Theses and Dissertations

This dissertation is an examination of growth, behavior, and dispersal during the early life stages of marine fishes in the Gulf of Mexico. Understanding movements of early life stages is a key part of managing exploited fish populations. Position in the water column can impact larval dispersal, since it determines those currents to which larvae are exposed. First, I investigated the relationship between length and age in early life stages of marine fishes. I found that demersal fish taxa tend to be represented by exponential models, while pelagic fish tend to be represented by linear models. I suggest this may …

Characterizing Childhood And Diet In Migration Period Hungary, Kirsten A. Verostick

USF Tampa Graduate Theses and Dissertations

This project investigates children, childhood and diet of two different Migration Period (4^th-8^th century AD) populations, the Gepids and the Avars, in the Great Hungarian Plain. The main goal was to assess whether there are differences in treatment of children and differences in breastfeeding and weaning practices in these distinct sites and populations. Secondarily, this research also focused on characterizing diet for the Gepids and the Avars at four different sites from the Migration Period, to understand how the migration and settling into the region and the assimilation of other groups into the two populations affected their …

Parent Coping And Sibling Relationship Quality In Pediatric Cancer: The Moderating Effects Of Parental Emotion Socialization Beliefs, Esther Davila

USF Tampa Graduate Theses and Dissertations

This study examined relations between parent coping and parent-, patient-, and sibling-reported perceptions of sibling relationship quality (SRQ), as well as potential moderating effects of parent emotion socialization (ES) beliefs in the context of pediatric oncology. Questionnaires were completed by 155 parents of pediatric oncology patients, 103 pediatric oncology patients, and 104 healthy siblings of pediatric oncology patients. Parent coping and ES beliefs predicted parent-perceived sibling warmth and dominance disparity. For parents low in emotion-dismissive ES beliefs, parent adaptive coping negatively predicted parent-perceived sibling dominance disparity. For parents low in emotion-coaching ES beliefs, parent adaptive coping positively predicted patient-perceived sibling …

Mapping Narrative Transactions: A Method/Framework For Exploring Multimodal Documents As Social Semiotic Sites For Ethnographic Study, Anne W. Anderson

USF Tampa Graduate Theses and Dissertations

This work grew from my attempts to find a method for studying a body of editorial cartoons—multi-modal documents producing cross-modal responses—that were created and published in an earlier time period, in order to answer questions about the culture in which the cartoons were produced and read. Initially my questions included wondering about the topics cartoonists addressed, the narratives cartoonists created to address the topics, how the narratives were framed, and in what ways the narratives might have been seen as attempts to shape the larger cultural discourse around the topics. However, given the number of possible combinations of information streams …

The Weekly Challenger, November 12, 2020, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The November 12, 2020, issue of The Weekly Challenger.

Environmental Influences On Expression Of Virulence- And Survival-Associated Genes And Epigenetic Modifications Of Dna In Vibrio Vulnificus, James W. Conrad

USF Tampa Graduate Theses and Dissertations

Vibrio vulnificus is an autochthonous inhabitant of warm, brackish coastal waters and is an opportunistic pathogen that causes the highest mortality of all seafood-related illnesses (1). These fatal infections are generally caused by the clinically-associated vcgC/16S rRNA type B genotypes within the biotype I group (2–5). However, the reasons for the heightened infectiousness of the clinically-associated strains over environmentally-associated ones remains elusive, as no unique clinically-associated virulence genes have been identified through genomic sequencing or other strategies. DNA methylation may contribute to regulation of virulence by affecting gene transcription, and was investigated in the highly virulent V. vulnificus strain CMCP6. …

Posttranslational Modification And Protein Disorder Regulate Protein-Protein Interactions And Dna Binding Specificity Of P53, Robin Levy

USF Tampa Graduate Theses and Dissertations

p53 is an intrinsically disordered transcription factor that suppresses tumor development by arresting the cell cycle and promoting DNA repair. p53 deletions or mutations can lead to cancer due to the inability of cells to respond to stress. The protein levels and post-translational modification state of p53 changes in response to cellular stress like DNA damage. Previous studies have shown that p53 can undergo coupled folding and binding with the E3 ubiquitin ligase, Mdm2, and the histone deacetylase, p300. In normal cells, p53 is kept at a low level by Mdm2, which marks it with ubiquitin, targeting p53 for proteasome …

Spatial And Temporal Determinants Associated With Eastern Equine Encephalitis Virus Activity In Florida, Kristi M. Miley

USF Tampa Graduate Theses and Dissertations

Eastern Equine Encephalitis virus (EEEV) is considered the most pathogenic mosquito-borne illness in the United States. Human mortality has been estimated to range between 35 to 75%, with horses experiencing mortality rates greater than 90%. A large number of EEEV cases occur in Florida. Though we have come a long way since the first human infection was identified in the 1930s, there is still much to learn regarding the virus’s ability to maintain transmission year-round in Florida. Phylogenic studies support that Florida may serve as the geographic reservoir for EEEV. This research investigated spatiotemporal and ecological variables associated with risk …

Networks In The Norm Life Cycle And The Diffusion Of Environmental Norms, James E. Fry

USF Tampa Graduate Theses and Dissertations

In this research, I analyze how Transnational Municipal Networks (TMNs) and cities affect the diffusion and transmission of a decarbonization norm. Urban policy and political science scholars assert that cities and their networks are influential in implementing internationally coordinated environmental policy. However, few projects have analyzed how local actors may diffuse environmental norms that have been developed in the international system. Using the norm life cycle, this research explores the transmission of a decarbonization norm by means of GHG measurement and mitigation. I identify two critical objectives associated with a decarbonization norm: establishing a system for monitoring GHG emissions and …

An Examination Of An Engagement Indicator For Non-Traditional First-Generation Black Students Enrolled In U.S. Institutions, Chantae D. Still

USF Tampa Graduate Theses and Dissertations

More students than ever have been provided access to higher education; however, the increase in enrollment is outpacing the data on successful completion rates. Student engagement has been identified as fundamental for college student success and retention.

The purpose of this study was to provide a description of the student engagement of non-traditional first-generation Black students attending 4-year public institutions in the United States. Using the Student-Faculty Interaction (SFI) National Survey of Student Engagement (NSSE) scales of student engagement, this study examined the relationship between SFI and selected personal characteristics of traditional and non-traditional, first-generation first-year and senior-year Black students, …

Maternal Social Status, Offspring 2d:4d Ratio And Postnatal Growth, In Macaca Mulatta (Rhesus Macaques), Juan Pablo Arroyo

USF Tampa Graduate Theses and Dissertations

Early life exposure to stressors can disrupt growth and development, resulting in long-term compromised function and increased risk for disease throughout the lifecourse. Maternal exposure to psychosocial stressors (i.e., stressors derived from social status, social inequalities, and social interactions) during pregnancy has been associated with reduced fetal growth, adverse birth outcomes, and increased morbidity for the offspring later in life. Maternal hormonal responses to stress, such as fluctuations in glucocorticoids (e.g., cortisol) and androgens (e.g., testosterone), can result in increased developmental instability, interfere with offspring growth in-utero, and may alter developmental processes of sexual dimorphism. Second digit to fourth digit …