Digital Commons Network^™

Hepatitis C Virus Infection And Intrinsic Disorder In The Signaling Pathways Induced By Toll-Like Receptors, Elrashdy M. Redwan, Abdullah A. Aljadawi, Vladimir N. Uversky

Molecular Medicine Faculty Publications

In this study, we examined the interplay between protein intrinsic disorder, hepatitis C virus (HCV) infection, and signaling pathways induced by Toll-like receptors (TLRs). To this end, 10 HCV proteins, 10 human TLRs, and 41 proteins from the TLR-induced downstream pathways were considered from the prevalence of intrinsic disorder. Mapping of the intrinsic disorder to the HCV-TLR interactome and to the TLR-based pathways of human innate immune response to the HCV infection demonstrates that substantial levels of intrinsic disorder are characteristic for proteins involved in the regulation and execution of these innate immunity pathways and in HCV-TLR interaction. Disordered regions, …

Intrinsic Disorder As A Natural Preservative: High Levels Of Intrinsic Disorder In Proteins Found In The 2600-Year-Old Human Brain, Aaron S. Mohammed, Vladimir N. Uversky

Molecular Medicine Faculty Publications

Proteomic analysis revealed the preservation of many proteins in the Heslington brain (which is at least 2600-year-old brain tissue uncovered within the skull excavated in 2008 from a pit in Heslington, Yorkshire, England). Five of these proteins—“main proteins”: heavy, medium, and light neurofilament proteins (NFH, NFM, and NFL), glial fibrillary acidic protein (GFAP), and myelin basic (MBP) protein—are engaged in the formation of non-amyloid protein aggregates, such as intermediate filaments and myelin sheath. We used a wide spectrum of bioinformatics tools to evaluate the prevalence of functional disorder in several related sets of proteins, such as the main proteins and …

Patient And Provider Perceptions Of A Community-Based Accompaniment Intervention For Adolescents Transitioning To Adult Hiv Care In Urban Peru: A Qualitative Analysis, Jerome T. Galea, Milagros Wong, Brennan Ninesling, Alicia Ramos, Liz Senador, Hugo Sanchez, Lenka Kolevic, Eduardo Matos, Eduardo Sanchez, Renato A. Errea, Andrew Lindeborg, Carlos Benites, Leonid Lecca, Sonya Shin, Molly F. Franke

Social Work Faculty Publications

Introduction: Adolescents living with HIV (ALWH) experience higher mortality rates compared to other age groups, exacerbated by the suboptimal transition from paediatric to adult HIV care, during which decreased adherence to antiretroviral therapy (ART) and unsuppressed viremia are frequent. Care transition—a process lasting months or years—ideally prepares ALWH for adult care and can be improved by interventions that are youth-friendly and address psychosocial issues affecting ART adherence; however, such interventions are infrequently operationalized. Community-based accompaniment (CBA), in which laypeople provide individualized support and health system navigation, can improve health outcomes among adults with HIV. Here, we describe patient and provider …

Considerations For Partnering With Ryan White Case Managers To Create Equitable Opportunities For People With Hiv To Participate In Research, Elizabeth Lockhart, Deanne Turner, Jerome T. Galea, Stephanie L. Marhefka

Social Work Faculty Publications

Many research studies focus on recruitment from one or few HIV clinics or internet-engaged populations, but this may result in inequitable representation of people with HIV (PWH), across the rural/urban/suburban continuum. Ryan White Case Managers (RWCM) meet regularly with PWH, potentially positioning them as partners in gathering research-related data from diverse groups of low-income, marginalized, PWH. Yet, data collection in partnership with RWCM, particularly over large geographic areas, has been under-explored. We partnered with RWCM and their organizations throughout Florida to administer a 10-item technology use and willingness survey to clients living with HIV; RWCMs provided process-oriented feedback. Among 382 …

Geographic Accessibility To Health Facilities Predicts Uptake Of Community-Based Tuberculosis Screening In An Urban Setting, Helen E. Jenkins, Sally Ayuk, Daniela Puma, Meredith B. Brooks, Ana Karina Millones, Judith Jimenez, Leonid Lecca, Jerome T. Galea, Mercedes Becerra, Salmaan Keshavjee, Courtney M. Yuen

Social Work Faculty Publications

Objectives: Annually, more than 30% of individuals with tuberculosis (TB) remain undiagnosed. We aimed to assess whether geographic accessibility measures can identify neighborhoods that would benefit from TB screening services targeted toward closing the diagnosis gap.

Methods: We used data from a community-based mobile TB screening program in Carabayllo district, Lima, Peru. We constructed four accessibility measures from the geographic center of neighborhoods to health facilities. We used logistic regression to assess the association between these measures and screening uptake in one's residential neighborhood versus elsewhere, with quasi-information criterion values to assess the association.

Results: We analyzed the screening locations …

Understanding Linkage To Biopsy And Treatment For Breast Cancer After A High-Risk Telemammography Result In Peru: A Mixed-Methods Study, Renato A. Errea, Patricia J. Garcia, Lydia E. Pace, Jerome T. Galea, Molly F. Franke

Social Work Faculty Publications

Objectives: This mixed-method study aimed to understand the effectiveness of linkage to biopsy and treatment in women with a high-risk mammography result (Breast Imaging Reporting and Data System, BI-RADS 4 and 5) in the national telemammography programme and to explore women’s experiences during this process.

Setting: Quantitative component: we collected and linked health data from the telemammography reading centre, the national public health insurance, the national centre for disease control and the national referral cancer centre. Qualitative component: we interviewed participants from different regions of the country representing diverse social and geographical backgrounds.

Participants: Quantitative: women who underwent telemammography between …

Attitudes Toward Payment For Research Participation: Results From A U.S. Survey Of People Living With Hiv, Andrea N. Polonijo, Karine Dubé, Jerome T. Galea, Karah Yeona Greene, Jeff Taylor, Christopher Christensen, Brandon Brown

Social Work Faculty Publications

Little is known about how payment affects individuals' decisions to participate in HIV research. Using data from a U.S. survey of people living with HIV (N = 292), we examined potential research participants’ attitudes toward payment, perceived study risk based on payment amount, and preferred payment forms, and how these factors vary by sociodemographic characteristics. Most respondents agreed people should be paid for HIV research participation (96%) and said payment would shape their research participation decisions (80%). Men, less formally educated individuals, and members of some minoritized racial-ethnic groups were less likely to be willing to participate in research …

Feasibility Of A School-Based Mental Health Program Implementation To Improve The Status Of Depression And Quality Of Life Of Mothers Of Children With Autism Spectrum Disorders In Urban Bangladesh: Menthol Study, Aliya Naheed, Saimul Islam, Meredith B. Brooks, Mary C. Smith Fawzi, Mir Nabila Ashraf, Helal Uddin Ahmed, M. M. Jalal Uddin, Kamrun Nahar Koly, Jerome T. Galea, Shaheen Akhter, Charles Nelson, Saima Wazed Hossain, Kerim M. Munir

Social Work Faculty Publications

Background: We assessed the feasibility of implementing psychological counseling services (PCS) for mothers of children with autism spectrum disorders (ASD) integrated within special education settings in urban Bangladesh. Method: In two special education schools for ASD in Dhaka City, trained female psychologists screened mothers using the Patient Health Questionnaire (PHQ-9). PCS was administered to all the mothers irrespective of a diagnosis of depression. Mothers with a PHQ-9 score >4 who met criteria for a major depressive episode (MDE) based on the DSM-IV Structured Interview Axis I Disorders (SCID-I) were also administered skill-building training through monthly home visits to support ASD …

Higher Native Peruvian Genetic Ancestry Proportion Is Associated With Tuberculosis Progression Risk, Samira Asgari, Yang Luo, Chuan-Chin Huang, Zibiao Zhang, Roger Calderon, Carmen Contreras, Jerome T. Galea, Leonid Lecca, David Jones, D. Branch Moody, Megan B. Murray, Soumya Raychaudhuri

Social Work Faculty Publications

No abstract provided.

Cardiovascular Risks And Sociodemographic Correlates Of Multidimensional Sleep Phenotypes In Two Samples Of Us Adults, Soomi Lee, Claire E. Smith, Meredith L. Wallace, Ross Andel, David M. Almeida, Sanjay R. Patel, Orfeu M. Buxton

Psychology Faculty Publications

Study Objectives

Sleep is a modifiable risk factor for cardiovascular conditions. Holistic examination of within-person, multidimensional sleep patterns may offer more detailed information about the sleep-cardiovascular condition link, including who is more vulnerable to both. This study aimed to identify common sleep phenotypes in adulthood, establish the validity of the phenotypes in relation to cardiovascular conditions, and explore sociodemographic and background characteristics of the phenotypes.

Methods

Across two independent samples of adults (N₁ = 4600; N₂ = 2598) from the Midlife in the United States Study, latent class analysis (LCA) extracted sleep phenotypes using five key self-reported …

Securing Elections Through International Law: A Tool For Combatting Disinformation Operations?, İrem Işik, Ömer F. Bi̇ldi̇k, Tayanç T. Molla

Journal of Strategic Security

According to the U.S. Department of Justice, in 2014, the Russian government-connected Internet Research Agency (IRA) initiated an information operation on social media platforms to manipulate the U.S. population concerning the 2016 U.S. presidential elections. This has revealed that social media platforms enable the spread of fake news among the masses globally and can thus become a means of disrupting the electoral process for foreign actors. This article addresses state-sponsored disinformation operations on social media that target foreign voters. It considers it crucial to counter such operations to protect the security and integrity of the elections in the digital age, …

A Deep Active Learning Approach To The Automatic Classification Of Volcano-Seismic Events, Grace F. Manley, Tamsin A. Mather, David M. Pyle, David A. Clifton, Mel Rodgers, Glenn Thompson, John Makario Londoño

School of Geosciences Faculty and Staff Publications

Volcano-seismic event classification represents a fundamental component of volcanic monitoring. Recent advances in techniques for the automatic classification of volcano-seismic events using supervised deep learning models achieve high accuracy. However, these deep learning models require a large, labelled training dataset to successfully train a generalisable model. We develop an approach to volcano-seismic event classification making use of active learning, where a machine learning model actively selects the training data which it learns from. We apply a diversity-based active learning approach, which works by selecting new training points which are most dissimilar from points already in the model according to a …

Obituaries, Altrusa International Of Tampa, Members, 2022, Altrusa International Of Tampa Bay, Inc.

Altrusa International of Tampa Bay, Inc. - Records

Obituaries for four members of the Altrusa International of Tampa for the year 2022.

Contributions Of Agroforestry Systems To Food Provisioning Of Peasant Households: Conflicts And Synergies In Chiapas, Mexico, Lorena Soto-Pinto, Sandra Escobar Colmenares, Marina Benítez Kanter, Angelita López Cruz, Erin Estrada Lugo, Balente Herrera Hernández, Estelí Jiménez-Soto

School of Geosciences Faculty and Staff Publications

Traditional agroforestry systems are widely recognized for their contributions to provisioning, support, regulation, and cultural services. However, because of the advancement of industrial agriculture and a corporative food system, peasants' food systems are rapidly undergoing transformation. We identify the contributions of four types of agroforestry systems (AFS)—shade cocoa agroforest, shade coffee agroforest, milpas and homegardens—to food provisioning in peasant families and discuss conflicts between traditional food systems and the contemporary industrial model of production and consumption confronted by peasants and semi-proletarian migrants. We carried out research in 17 peasant communities in Chiapas, Mexico, and conducted 97 semi-structured interviews and agroecological …

The Role Of Influential Actors In Fostering The Polarized Covid-19 Vaccine Discourse On Twitter: Mixed Methods Of Machine Learning And Inductive Coding, Loni Hagen, Ashley Fox, Heather O'Leary, Deandre Dyson, Kimberly Walker, Cecile A. Lengacher, Raquel Hernandez

School of Information Faculty Publications

Background: Since COVID-19 vaccines became broadly available to the adult population, sharp divergences in uptake have emerged along partisan lines. Researchers have indicated a polarized social media presence contributing to the spread of mis- or disinformation as being responsible for these growing partisan gaps in uptake.

Objective: The major aim of this study was to investigate the role of influential actors in the context of the community structures and discourse related to COVID-19 vaccine conversations on Twitter that emerged prior to the vaccine rollout to the general population and discuss implications for vaccine promotion and policy.

Methods: We collected tweets …

Usft 2022-2023 Usf Libraries Annual Report, Usf Libraries

Library Annual Reports

No abstract provided.

The Legacy Of Hurricanes, Historic Land Cover, And Municipal Ordinances On Urban Tree Canopy In Florida (United States), Allyson B. Salisbury, Andrew K. Koeser, Richard J. Hauer, Deborah R. Hilbert, Amr H. Abd-Elrahman, Michael G. Andreu, Katie Britt, Shawn Landry, Mary G. Lusk, Jason W. Miesbauer, Hunter Thorn

School of Geosciences Faculty and Staff Publications

Urban Tree Canopy (UTC) greatly enhances the livability of cities by reducing urban heat buildup, mitigating stormwater runoff, and filtering airborne particulates, among other ecological services. These benefits, combined with the relative ease of measuring tree cover from aerial imagery, have led many cities to adopt management strategies based on UTC goals. In this study, we conducted canopy analyses for 300 cities in Florida to assess the impacts of development practices, urban forest ordinances, and hurricanes on tree cover. Within the cities sampled, UTC ranged from 5.9 to 68.7% with a median canopy coverage of 32.3% Our results indicate that …

The Weekly Challenger, December 23, 2021, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The December 23, 2021, issue of The Weekly Challenger.

Wwa Reflection: Building Writing Momentum: A Year Of Digital Conferences, Brianna E. Robertson-Kirkland

ABO: Interactive Journal for Women in the Arts, 1640–1830

This reflection, which considers the positive impact of attending online conferences on building writing momentum is in response to the ABO Call for Short Reflections (500-750 words) on Writing and Research during the Pandemic.

Guest Editorial: Mass Atrocity And Collective Healing: New Possibilities For Regenerating Communities, Scherto R. Gill

Genocide Studies and Prevention: An International Journal

This Special Issue brings together five articles from different disciplines. It aims to contribute to the emergent critical voices in research about collective trauma and collective healing by introducing novel perspectives and inviting further debates on the relevant issues evoked. For this reason, the Special Issue focuses on collective healing through a number of prisms. First, it delves into the notions of wounding and trauma, with a view to advance a well-argued theoretical framework for understanding collective healing. Second, it identifies underlying ethical pillars for collective healing, especially the principles of equality and well-being that affirm human dignity founded on …

Legacies Of Slavery And Their Enduring Harms, Scherto R. Gill

Genocide Studies and Prevention: An International Journal

This article provides a much needed inquiry into the legacy of slavery from an interdisciplinary perspective, including the historical, socioeconomic, political, and the epistemic. It makes an important distinction between the legacy of slavery and its persisting damages. By investigating this legacy’s effects on peoples, communities, and societies, it highlights the imperative of situating the pains and sufferings of historical traumas within contemporary structural oppression and institutional discrimination that have perpetuated these harms. The article consists of four sections: it first outlines the legacy of slavery, comprised in instrumentalizing black bodies for economic gains, employing political aggression to colonize both …

Full Issue 15.3

Genocide Studies and Prevention: An International Journal

No abstract provided.

Collective Healing To Address Legacies Of Transatlantic Slavery: Opportunities And Challenges, Scherto R. Gill, Garrett Thomson

Genocide Studies and Prevention: An International Journal

In this article, we show how pathways to justice and reconciliation pertaining to the transatlantic slavery should begin with collective healing processes. To illustrate this conclusion, we first employ a four-fold conceptual framework for understanding collective healing that consists in: (1) acknowledging historical dehumanizing acts; (2) addressing the harmful effects of dehumanisation; (3) embracing relational rapprochement; and (4) co-imagining and co-creating conditions for systemic justice. Based on this framework, we then examine existing collective healing practices in different contexts that are aimed at addressing legacies of transatlantic slavery. In doing so, we further identify challenges and pose critical questions concerning …

Ongoing Genocides And The Need For Healing: The Cases Of Native And African Americans, Benjamin P. Bowser, Carl O. Word, Kate Shaw

Genocide Studies and Prevention: An International Journal

The elimination of Native peoples and the enslavement of Africans in the U.S. more than qualify as acts of historical state sponsored genocide. A feature of both genocides is that they ended as institutional practices but have continued culturally and psychologically. The primary contemporary legacy of these genocides is racism which reinforces historical trauma and grief. Suggestions are made for how healing for Native and African Americans can begin despite ongoing racism. This includes psychological counseling for White Americans with beliefs in White supremacy. Suggestions are also made for how reconciliation can begin at the county-level between descendants of slave …

A Dance Of Shadows And Fires: Conceptual And Practical Challenges Of Intergenerational Healing After Mass Atrocity, Brandon Hamber, Ingrid Palmary

Genocide Studies and Prevention: An International Journal

The legacy of mass atrocity—including colonialism, slavery or specific manifestations such as apartheid—continue long after their demise. Applying a temporal intergenerational lens adds complications. We argue that mass atrocity creates for subsequent generations a deep psychological rupture akin to witnessing past atrocities. This creates a moral liability in the present. Healing is a process dependent on the authenticity (evident in discourse and action) with which we address contemporary problems. A further overriding task is to open social and political space for divergent voices. Acknowledgement of mass atrocity requires more than one-off events or institutional responses (the grand apology, the truth …

Book Review: Are Perpetrators Under-Researched?, Christian Gudehus

Genocide Studies and Prevention: An International Journal

No abstract provided.

Monitoring Photosynthetic Activity Using In Vivo Chlorophyll A Fluorescence In Microalgae And Cyanobacteria Biofilms In The Nerja Cave (Malaga, Spain), Yolanda Del Rosal, Juan Muñoz-Fernández, Paula S.M. Celis-Plá, Mariona Hernández-Mariné, Félix Álvarez-Gómez, Salvador Merino, Félix L. Figueroa

International Journal of Speleology

The characterization of the most common photosynthetic biofilms in the Nerja Cave by the continuous monitoring of the in vivo chlorophyll a (Chl a) fluorescence and the incorporation of the irradiance as a new environmental variable related to previous studies in the cave, have allowed us to improve our knowledge about the photosynthetic pattern of the biofilms of the cave. Effective quantum yield (ΔF/F_m′) and relative electron transport rate (rETR) were determined during periods of the light, whereas the maximal quantum yield (F_v /F_m) was determined during dark periods. Increases in …

A Preliminary Study Of Radon Equilibrium Factor At A Tourist Cave In Okinawa, Japan, Ryohei Yamada, Yuki Tamakuma, Takahito Suzuki, Shunya Nakasone, Yoshitaka Shiroma, Masahide Furukawa, Hiroki Hashimoto, Masahiro Hosoda, Naofumi Akata, Shinji Tokonami

KIP Articles

The International Commission on Radiological Protection (ICRP) issued its Publication 137, Occupational Intakes of Radionuclides: Part 3 in which the radon equilibrium factor is fixed as 0.4 for tourist caves; however, several studies have reported a different value for the factor and its seasonal variation has also been observed. In this study, the radon concentration, equilibrium equivalent radon concentration and meteorological data were measured, and the equilibrium factor was evaluated in a tourist cave, Gyokusen-do Cave located in the southern part of Okinawa Island in southwestern Japan. Radon concentrations were measured with an AlphaGUARD and their corresponding meteorological data were …

The Weekly Challenger, December 9, 2021, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The December 9, 2021, issue of The Weekly Challenger.

Happy Holidays [December 2021], Cutr

CUTR Newsletters

No abstract provided.