Digital Commons Network^™

Aldosterone Treatment Protects Connexin 30 And 43 Expression For Age-Related Hearing Loss, Jennifer A. Pineros Valencia

USF Tampa Graduate Theses and Dissertations

Age-related hearing loss (ARHL), also known as presbycusis, is the number one communication disorder affecting our aged population. Connexin proteins are essential for intercellular communication throughout the human body. Mutations in connexin genes have been linked to human syndromic and nonsyndromic deafness; thus, we hypothesize changes in connexin gene and protein expression with age may be involved in the development of ARHL. In our current study, connexin mRNA gene expression for CBA/CaJ mice at different age points were examined and correlations were analyzed between the changes in gene expression and functional hearing measures, such as ABRs and DPOAEs. Moreover, we …

Ay 2022/2023 Fs Agenda, 2022-11-16, Faculty Senate

Faculty Senate Archives

No abstract provided.

Ay 2022/2023 Fs Meeting Minutes, 2022-11-16, Faculty Senate

Faculty Senate Archives

No abstract provided.

Relationship Between Individual Characteristics And Received Social Support Among People With Serious Mental Illness, Samantha Dicorte

USF Tampa Graduate Theses and Dissertations

Past research on social support has mainly focused on perceived social support. Relatively less research has been done on received social support and how it can promote positive behavior outcomes. This study examines the importance of received social support, including background on social support, social support outcomes, and a theoretical foundation overview of the social stress model. In addition to a literature review, this study investigates the association between individual characteristics (i.e., diagnosis and substance abuse including alcohol, race/ethnicity, gender, age, and marital status) and different types of received social support (i.e., daily, mental health, and adherence support). Simple linear …

Leveraging Smart-Phone Cameras And Image Processing Techniques To Classify Mosquito Genus And Species, Sriram Chellappan, Pratool Bharti, Mona Minakshi, Willie Mcclinton, Jamshidbek Mirzakhalov

USF Patents

Identifying insect species integrates image processing, feature selection, unsupervised clustering, and a support vector machine (SVM) learning algorithm for classification. Results with a total of 101 mosquito specimens spread across nine different vector carrying species demonstrate high accuracy in species identification. When implemented as a smart-phone application, the latency and energy consumption were minimal. The currently manual process of species identification and recording can be sped up, while also minimizing the ensuing cognitive workload of personnel. Citizens at large can use the system in their own homes for self-awareness and share insect identification data with public health agencies.

Theoretical And Experimental Analyses Of Acoustofluidic Phenomena For Biosensing Applications, Pradipta Kr. Das

USF Tampa Graduate Theses and Dissertations

Acoustofluidics is a well-proven tweezer serving various applications such as particle manipulation, cell trapping and separations, fluid mixing, and bio-sensing. In this thesis, we explored several aspects of acoustofluidics such as acoustic streaming, acoustothermal heating and acoustophoretic manipulations of micron sized objects, in the context of biosensing applications.

In Chapter 2, inner acoustic streaming for second-order fluids has been studied analytically by employing asymptotic expansions for thin Stokes layer and low acoustic Mach number. In addition, a multiple-time-scale approach has been adopted to separate the primary oscillatory flow and the steady acoustic streaming. The study considers two sample cases: (i) …

Crow's Nest, November 14, 2022, Crow's Nest Staff

Crow's Nest

The November 14, 2022, issue of the Crow's Nest.

L-Ergothioneine Treatment In Old Cba/Caj Male Mice Slows The Progression Of Age-Related Hearing Loss, Mark A. Bauer

USF Tampa Graduate Theses and Dissertations

The naturally occurring amino acid, L-Ergothioneine (EGT), has immense potential as a therapeutic, having shown promise in the treatment of other disease models, including neurological disorders. EGT is naturally uptaken into cells via its specific receptor, OCTN1, suggesting that it is highly conserved, to be utilized by cells as an antioxidant and anti-inflammatory, particularly under stressed conditions. In our current study, EGT was administered over a period of 6 months to 25-26 month old CBA/CaJ mice as a possible treatment for age-related hearing loss (ARHL), since presbycusis has been linked to higher levels of cochlear oxidative stress, apoptosis and chronic …

Optimizing Lake Okeechobee Watershed Management And Reservoir Operations For Water Quality Improvement, Osama Mahrous Mossad Tarabih

USF Tampa Graduate Theses and Dissertations

Rivers around the globe have been altered as people have constructed water resources infrastructure to store water for different human needs, causing negative impacts on ecosystem processes and functions. Environmental flows have been introduced to restore deteriorated riverine ecosystems; however, environmental flows have not always been practical or adequate to restore environment conditions in rivers globally. Lake Okeechobee is a large subtropical lake that plays a pivotal role in South Florida water system providing various water demands for the surrounding communities as well as providing crucial services to the ecosystem of South Florida. However, hydrologic alterations and nutrient (phosphorus and …

Reproduction In Relation To Heavy-Metal Contamination Along An Urbanization Gradient In Aninvasive Florida Lizard Species (Anolis Sagrei), Elizabeth Hauck

USF Tampa Graduate Theses and Dissertations

Environmental contamination is accumulating rapidly worldwide due to increasing urbanization rates. Heavy metals are known to be particularly toxic to organisms, to accumulate in biological systems, and to be found in higher concentrations in animals located in areas of high urban levels. However, the physiological impacts of these toxic heavy metals in wildlife remain largely unknown. Lizards are excellent bioindicator species for environmental contaminants due to their trophic level as mesopredators and their susceptibility of exposure via air, water, diet, and soil through egg deposition. To assess the impacts heavy-metal contamination has on reproductive parameters in lizards and how these …

Evaluating The Effect Of Public Health Governance Structure And Public Opinion On Covid-19 Disease Control Interventions, Daniel Chacreton

USF Tampa Graduate Theses and Dissertations

Background

Since the start of the COVID-19 outbreak, the responses to the pandemic varied greatly from nation to nation. In the US, state-level variance in responses has likely contributed to the disparate COVID-19 infection-related state-level outcomes such as incidence and case fatality rates. The large variances in national and sub-national responses to COVID-19 when combined with the abundance of factors that influence disease transmission rates has created a number of important research opportunities.

Methods

In this vain, this research study aims to describe the relationship that exists between public health governance structure and public sentiment and COVID-19 control measure effectiveness …

The Weekly Challenger, November 10, 2022, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The November 10, 2022, issue of The Weekly Challenger.

Using Gis-Based Land Use Strategies To Minimize The Impacts Of Urbanization On Agricultural Land And Forest Cover: Case Study Of The City Of Limbe, Cameroon, Lucy Ebude Deba Enomah

USF Tampa Graduate Theses and Dissertations

Urbanization is one of the most dominant phenomena of the 21st century; it is propelled by natural growth and rural-to-urban migration. This latter is typically a product of rural residents moving to urban centres in search of economic opportunities. This phenomenon is accompanied by immense land use and cover changes – predominantly agricultural and forest lands to urban land uses such as buildings and infrastructure. The goal of this research was to contribute to efforts to minimize the impacts of urbanization on agricultural land and forest cover in Limbe, Cameroon, and to develop GIS-based strategies to allocate suitable land for …

Development Of Lipidated Antimicrobial Polycarbonates, Ruixuan Gao

USF Tampa Graduate Theses and Dissertations

Antimicrobial resistance is a global challenge owing to the lack of discovering effective antibiotic agents. Antimicrobial polymers containing the cationic groups and hydrophobic groups which mimic natural host-defense peptides (HDPs) show great promise in combating bacteria. Herein, we report the synthesis of lipidated polycarbonates bearing primary amino groups and hydrophobic moieties (including both the terminal lipid alkyl chain and hydrophobic groups in the sequences) by ring-opening polymerization. The hydrophobic/hydrophilic group ratios were adjusted deliberately and the lengths of the lipid tails at the end of the polymers were modified to achieve the optimized combination for the lead polymers, which exhibited …

Structural And Biochemical Characterization Of Epigenetic And Fusion Tyrosine Kinase Cancer Targets For Drug Development, Melissa Bikowitz

USF Tampa Graduate Theses and Dissertations

Cancer is a significant global health burden, as ~40% of the human population is diagnosed with cancer over a lifetime, half of which succumb to the disease. To develop novel compounds as potential cancer therapeutics, an in-depth structural and biochemical understanding of proteins involved in oncogenesis is key. This dissertation centers around the comprehensive structural and biochemical characterization of two classes of proteins critical for cancer cell survival: bromodomain-containing proteins (BRDs) and fusion tyrosine kinases (FTKs).In 2010, small molecule inhibitors targeting bromodomains (epigenetic reader proteins) became heavily popularized due to the druggability and potent anticancer effects of BET inhibitors. …

Orthogonal Saw Biosensor Fem Simulation Based On St-Quartz With Crystalline Zno Guiding Layer, Saurabh Patwardhan

USF Tampa Graduate Theses and Dissertations

Detection of trace amounts of biomarkers is a critical requirement in sensing the presence of conditions such as early-stage cancer. The ST cut of the Quartz crystal (ST-Quartz) supports two fundamental surface acoustic waves (SAWs) in mutually perpendicular, or orthogonal, directions: the Rayleigh wave and the shear-horizontal wave (RSAW and SH-SAW, respectively). The orthogonality enables the use of ST-Quartz in biofouling removal by the RSAW and mass sensing via the SH-SAW simultaneously. The purpose of this study is to find an ideal guiding layer and wavelength configuration that can enhance the sensing capability without sacrificing the biofouling removal ability for …

Community Heritage: A Source Of Health/Medical Aspirational Capital For Black Males, Lafrance Clarke Jr.

USF Tampa Graduate Theses and Dissertations

There is a recognized need for more Black male healers who pursue careers in medical fields.Thus, the purpose of this study was twofold: to explore historical documents to tell the histories of men of African descent who practiced healing in Florida and, from those histories, create a virtual heritage tour to support teaching about leadership through African American history and narratives of healing. The research questions were: How does the heritage curriculum history about Black men healers of FL provide a historical counter-narrative about Black men and their leadership in connection to health/medicine?How do historical counter-narratives about Black men support …

Low-Pressure Plasma Surface Treatment Of Polycarbonate And Polyacrylic Plates With Different Plasmas And Their Characterization, Suleyman Gorkem Gizer

USF Tampa Graduate Theses and Dissertations

In this thesis, polycarbonate (PC) and acrylic (PMMA) surfaces were treated with carbon tetrafluoride (CF4), oxygen (O2), and air plasmas with a low-pressure plasma method in order to change their surface properties such as surface free energy and wettability. Moreover, different pattern sized, line, triangular and square shaped surface patterns were used to determine the shape and size-dependent changes. The characteristics of untreated and plasma treated surfaces were examined via contact angle (CA) measurements with distilled (DI) water, against plasma treatment number. Moreover, surface free energy (SFE) calculations of the PC and PMMA surfaces were carried out from sessile drop …

Assisted Living Administrators’ Perspectives Of How Covid-19 Affected Direct Care Staff, Carlyn E. Vogel

USF Tampa Graduate Theses and Dissertations

Background: Coronavirus disease 2019 (COVID-19) presented many new challenges within assisted living communities (ALCs) and exacerbated preexisting challenges. With high quality of care in ALCs as the continuous goal to achieve, it is important to recognize challenges faced in these communities, especially those related to staffing and COVID-19.

Objective: The objective was to investigate issues related to staffing and the effect of COVID-19 in ALCs, including staff absence, leadership, impacts on staff, and impacts on staff retention.

Methods: Participants were ALC administrators from the NIA-funded parent study titled Strategic Approach to Facilitating Evacuation by Health Assessment of Vulnerable Elderly in …

Standardization Of Care For Transition-Age Youth At Emancipation: An Analysis Of Service Provision, Sarah K. Sheffield

USF Tampa Graduate Theses and Dissertations

The Florida Department of Children and Families notes community-based care (CBC) agencies are competent entities who present with their own method of service delivery and design. Recent evaluations show concerns in service selection to include a tendency to choose programming based on face validity, a lack of capacity and availability of services by geographical location, and a failure to systematically encompass stakeholder voice. The purpose of this study was to gain insight on how agencies make decisions regarding the selection of services for transition-age youth at emancipation.

A set of direct care providers from CBC and non-profit agencies participated in …

An Examination Of Parental Coping Strategies During Catastophic Events, Vivian K. Mills

USF Tampa Graduate Theses and Dissertations

On March 11, 2022, the World Health Organization (WHO) declared the Sars CoV-2 a global pandemic. The virus that originated in Wuhan, China, had spread to several other countries causing governments to shut down and issue safety mandates to slow and stop the spread. The pandemic caused global changes to normal routines and highlighted the importance of coping during these tough times. Although the global COVID-19 pandemic encompassed much of the news during the past few years, it is not an isolated catastrophic event to have impacted society. Natural disasters, such as hurricanes and wildfires, wars, and other disasters have …

Farmer Adoption Of Advanced Technology In Agribusiness, Justin W. Belcher

USF Tampa Graduate Theses and Dissertations

Normally, family-owned farms are slow to adopt advanced technologies though these technologies can provide several benefits to the farm and have the potential to increase farm production volumes to help meet future population growth. The goal of this study was to document the factors that influence the adoption decision of advanced technologies by family-owned farms and what strategies can be used to motivate adoption. Case study research was conducted to gather data in a more structured way from family-owned farms typically excluded from past research for the purpose of comparing similarities across similar and dissimilar farms. For generalizing similarities, a …

Anthropogenic Fecal Pollution Affects Microbial Water Quality And Multidrug Resistance In Tropical Aquatic Environments, Adriana González-Fernández

USF Tampa Graduate Theses and Dissertations

Although an often-overlooked issue, fecal pollution at recreational beaches should concerneveryone. Worldwide more than 80% of wastewater is discharged into rivers or the ocean without any treatment. Untreated and inefficiently treated wastewater can introduce diseasecausing microorganisms into the aquatic environment. Fecal-borne pathogens can also originate in animal waste, and humans can be exposed to these pathogens from poorly managed animal feces that make their way into the aquatic environment. Exposure to waterborne pathogens in recreational waters is a public health hazard, as it facilitates the transmission of waterborne illness, and surface waters serve as natural reservoirs of antibiotic resistant bacteria …

Interaction Of Sequentially Applied Interventions For Gait Symmetry, Adila Hoque

USF Tampa Graduate Theses and Dissertations

More than 50% of stroke survivors over 65 years of age experience long-term mobilityloss [50]. Hemiparesis is a form of disability that arises from this, causing paralysis on one side of the body. The long-term effects of hemiparesis include loss of locomotion, muscle spasticity, and excessive use of muscles on the non-paretic side. This leads to a gait pattern that is kinematically and kinetically asymmetric.

Several rehabilitation techniques currently exist that aim to minimize this asymmetric gait, including split-belt treadmill training, rhythmic cueing (auditory or tactile), adding mass to one foot. Each form of treatment comes with its unique strengths …

Surviving A Broken System: Synergies Between Solidarity Economies And Sustainable Development Goals, Julie Beach

USF Tampa Graduate Theses and Dissertations

Capitalism has created problems including wealth polarization, rapid depletion of natural resources, and pervasive systemic societal issues. Hard work is not enough to solve the unequal distribution and barriers preventing access to necessities. Sustainable Development Goals (SDGs) were created to remedy the harsh reality of global inequities and negative environmental impacts by working towards a more just and equitable future for all. Solidarity Economies (SE) offer an alternative framework to achieve these goals.

This research used multiple qualitative methods to investigate the synergies between SE and SDGs in a growing urban environment. St. Petersburg, FL struggles with affordable housing, food …

Towards Precision Audiology: Perceptual Profiles & Their Relation To Ecologically Valid Communication Assessments, Dana Cherri

USF Tampa Graduate Theses and Dissertations

Living in a sonic world, a person with hearing loss experiences difficulty in communicating with others. One of the reasons why some people with hearing loss do not wear hearing aids (HAs) is limited perceived benefit, which may result from HAs that are not fit using “best practices” or because the best practices fail to address individual difficulties experienced by the listener. The typical audiogram provides information regarding audibility as a function of frequency and is used to establish degree, type, and configuration of hearing loss, but does not measure the ability of an individual to process various components of …

The Impact Of Critical Illness Insurance Among Older Adults In China, Jiaosi Li

USF Tampa Graduate Theses and Dissertations

Although China has made considerable progress towards universal health insurance coverage, high out-of-pocket medical expenditures due to catastrophic illnesses (e.g., cancer, heart attack, or stroke) remain a concern. To address this concern, the Critical Illness Insurance (CII) program providing additional coverage for high medical expenditures was introduced in 2012. We combine data on the timing of CII implementation across prefecture cities in China with the China Health and Retirement Longitudinal Study (CHARLS) to examine its impact on medical expenditures, inpatient utilization, health outcomes, household consumption and savings. To account for the staggered implementation across regions, we employ the Difference-in-Differences (DiD) …

Development Of An Automated Platform For Sensing And Differentiating Vapor-Phase Btex Constituents, Jonathan Samuelson

USF Tampa Graduate Theses and Dissertations

Light aromatic hydrocarbons are an inevitable byproduct of fossil fuel extraction, refinement, distribution, and use. The four lightest and most prevalent of these are benzene, toluene, ethylbenzene, and xylene, which are known collectively as BTEX. In spite of their chemical similarity these species have markedly different effects on human health and substantially different concentrations are permitted by OSHA in workplaces and by the EPA in ambient air and groundwater. Real-time detection, identification, and quantification of these species is therefore of great importance wherever they see industrial use.This work represents the continuation and advancement of a line of research in which …

An Anthropology With Human Waste Management: Non-Humans, The State, And Matters Of Care On The Placencia Peninsula, Belize, William Alex Webb

USF Tampa Graduate Theses and Dissertations

The management of human waste is a seldom studied phenomenon in anthropology. Yet across the globe, in countries both rich and poor, it presents pervasive and difficult to tame problems. This dissertation draws on complimentary theories of management and entanglements to explore the practices and processes of organizing human waste on the Placencia Peninsula, Belize. The results illustrate how problems are conditioned and defined by messy relations between institutions, people, technologies, materials, and ecological life.

Fieldwork and analysis for this work was a culmination of years of interdisciplinary collaboration between other anthropologists and engineers at the University of South Florida. …

Statistical Methods For Reliability Test Planning And Data Analysis, Oluwaseun Elizabeth Otunuga

USF Tampa Graduate Theses and Dissertations

This dissertation develops several statistical methods to advance the techniques and applications in the fields of reliability test planning and data analysis as well as statistical modeling and analysis in survival analysis.

The first project focuses on developing new demonstration test plans for lifetime data based on considering multiple objectives. Reliability demonstration tests have been broadly used for assuring reliability performance at the desired confidence level. We consider lifetime data that follows a Weibull distribution which has been broadly used for modeling a variety of shapes of lifetime distributions. When planning a demonstration test, there are often multiple aspects to …