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Full-Text Articles in Entire DC Network
Performance History Of Mahler’S Das Lied Von Der Erde Focusing On Bruno Walter And Leonard Bernstein, Nisan Ak
Performance History Of Mahler’S Das Lied Von Der Erde Focusing On Bruno Walter And Leonard Bernstein, Nisan Ak
Theses and Dissertations
This document will explore the relationship between performance practices of Bruno Walter’s and Leonard Bernstein’s interpretations of Das Lied von der Erde. Bruno Walter was a student and assistant of Gustav Mahler. The composer never heard his unnumbered symphony played by an orchestra. Walter gave the first performance of the piece and made the first recording. This author considers Leonard Bernstein to be Walter's interpretational successor of Das Lied von der Erde. Throughout the document, the author will explore the relationship between the three musicians through the analysis of Das Lied and a detailed exploration of interpretations of …
Online Technology Integration Professional Development: Action Research Evaluating Impact On Faculty Perceptions And Practices, Anna Loftus
Theses and Dissertations
Many faculty teaching online lack the skills and knowledge in technology to effectively integrate technology into their course design. Faculty feel they are not provided enough professional development opportunities to improve their technology integration skills. Therefore, online professional development specifically designed for online faculty interested in integrating technology into their course design can assist in preparing faculty for the online classroom. The purpose of this action research was to implement and evaluate the impact of online technology integration professional development for faculty teaching at a distance at an institution of higher education. This study focused on three research questions. The …
Implementation And Evaluation Of Computer-Assisted Science Vocabulary Modules With Students With An Intellectual Disability And Autism: An Action Research Study, Jamie Lee Taber
Theses and Dissertations
Students with disabilities are struggling to meet expectations in science at the national and local level. Many studies have linked difficulties with science content to difficult and technical vocabulary, and this has been evident at the local level, too. To try to improve science instruction for students with disabilities, the purpose of this study was to evaluate the implementation of computer-assisted science vocabulary modules with students with an intellectual disability and autism in an adapted environmental science class. This study aimed to answer how the implementation of computer-assisted vocabulary modules, which adhere to evidence-based practices of special education vocabulary instruction, …
A Comparative Study Of Cannabinoids & Cb1 Receptor Gi Signaling, Haley Kristen Andersen
A Comparative Study Of Cannabinoids & Cb1 Receptor Gi Signaling, Haley Kristen Andersen
Theses and Dissertations
The legalization of medical marijuana has highlighted cannabinoids as a potential, opioid-free therapeutic option for pain management; however, the rise in illicit synthetic cannabinoid-induced toxicity has demonstrated the need to outline cannabinoid molecular signaling. The cannabinoid-type 1 (CB1) receptor is an endogenous G protein-gated receptor (GPCR), well-expressed in the central nervous system (CNS) associated with modulating neuronal activity. Cannabinoid agonists bind to the CB1 receptor resulting in the inhibitory G protein (Gi) complex to dissociate into two subunits, Gβγi and Gαi. The Gαi subunit inhibits adenylyl cyclase, leading to a decrease in cyclic adenosine monophosphate (cAMP). The Gβγi subunit activates …
African American Emerging Adult Perspectives On Unintended Pregnancy And Meeting Their Needs With Mobile Technology: Mixed Methods Qualitative Study, Lucy Annang Ingram, Crystal Stafford, Quentin Mccollum, Mckenzie Isreal
African American Emerging Adult Perspectives On Unintended Pregnancy And Meeting Their Needs With Mobile Technology: Mixed Methods Qualitative Study, Lucy Annang Ingram, Crystal Stafford, Quentin Mccollum, Mckenzie Isreal
Faculty Publications
Background: In the United States, a disproportionate number of unintended pregnancies occur among African Americans, particularly those in their later teenage years and early 20s. Mobile technology is becoming more ubiquitous as a method for health promotion; however, relatively little research has been done with this population to determine their perspectives about unintended pregnancy, the potential of successfully using mobile technology to prevent unintended pregnancy, and the content of such programs.
Objective: The purpose of this study was to obtain the perspectives of African American emerging adults about unintended pregnancy and the use of mobile technology to reduce unintended pregnancy …
Early Breastfeeding Practices Contribute To Exclusive Breastfeeding In Bangladesh, Vietnam And Ethiopia, Phuong Hong Nguyen, Sunny S. Kim, Lan Mai Tran, Purnima Menon, Edward A. Frongillo Jr.
Early Breastfeeding Practices Contribute To Exclusive Breastfeeding In Bangladesh, Vietnam And Ethiopia, Phuong Hong Nguyen, Sunny S. Kim, Lan Mai Tran, Purnima Menon, Edward A. Frongillo Jr.
Faculty Publications
Limited evidence exists on the complex relationship among interventions, early initiation of breastfeeding (EIBF), prelacteal feeding and exclusive breastfeeding (EBF). We examined whether early breastfeeding practices are associated with EBF and how much improving EIBF and non-prelacteal feeding contributes to increased prevalence of EBF. Survey data were collected in 2010 and 2014 as part of impact evaluations of Alive & Thrive (A&T) interventions to improve infant and young child feeding (IYCF) practices in Bangladesh, Vietnam and Ethiopia. Multivariable logistic regression analyses were used to examine effects of interventions and early breastfeeding practices on EBF. Structural equation modelling quantified the direct …
Obesity Worsens Gulf War Illness Symptom Persistence Pathology By Linking Altered Gut Microbiome Species To Long-Term Gastrointestinal, Hepatic, And Neuronal Inflammation In A Mouse Model, Dipro Bose, Punnag Saha, Ayan Mondal, Brian Fanelli, Ratanesh K. Seth, Patricia Janulewicz, Kimberly Sullivan, Stephen Lasley, Ronnie Horner, Rita R. Colwell, Ashok K. Shetty, Nancy Klimas, Saurabh Chatterjee
Obesity Worsens Gulf War Illness Symptom Persistence Pathology By Linking Altered Gut Microbiome Species To Long-Term Gastrointestinal, Hepatic, And Neuronal Inflammation In A Mouse Model, Dipro Bose, Punnag Saha, Ayan Mondal, Brian Fanelli, Ratanesh K. Seth, Patricia Janulewicz, Kimberly Sullivan, Stephen Lasley, Ronnie Horner, Rita R. Colwell, Ashok K. Shetty, Nancy Klimas, Saurabh Chatterjee
Faculty Publications
Persistence of Gulf War illness (GWI) pathology among deployed veterans is a clinical challenge even after almost three decades. Recent studies show a higher prevalence of obesity and metabolic disturbances among Gulf War veterans primarily due to the existence of post-traumatic stress disorder (PTSD), chronic fatigue, sedentary lifestyle, and consumption of a high-carbohydrate/high-fat diet. We test the hypothesis that obesity from a Western-style diet alters host gut microbial species and worsens gastrointestinal and neuroinflammatory symptom persistence. We used a 5 month Western diet feeding in mice that received prior Gulf War (GW) chemical exposure to mimic the home phase obese …
Redox-Sensitive Nanocomplex For Targeted Delivery Of Melittin, Bei Cheng, Peisheng Xu
Redox-Sensitive Nanocomplex For Targeted Delivery Of Melittin, Bei Cheng, Peisheng Xu
Faculty Publications
Although peptide therapeutics have been explored for decades, the successful delivery of potent peptides in vitro and in vivo remains challenging due to the poor stability, low cell permeability, and off-target effects. We developed a redox sensitive polymer-based nanocomplex which can efficiently and stably deliver the peptide drug melittin for cancer therapy. The nanocomplex selectively targets cancer cells through lactobionic acid mediated endocytosis and releases melittin intracellularly upon the trigger of elevated redox potential. In vivo study proved that the targeted nanocomplex shows excellent potency in inhibiting tumor growth in a xenograft colon cancer mouse model. Thus, the polymer/melittin nanocomplexes …
September 9, 2020 Faculty Senate Minutes, University Of South Carolina
September 9, 2020 Faculty Senate Minutes, University Of South Carolina
Faculty Senate
No abstract provided.
Context-Specific Challenges, Opportunities, And Ethics Of Drones For Healthcare Delivery In The Eyes Of Program Managers And Field Staff: A Multi-Site Qualitative Study, Vyshnave Jeyabalan, Elysée Nouvet, Patrick Meier, Lorie Donelle Phd, Rn, Fcan
Context-Specific Challenges, Opportunities, And Ethics Of Drones For Healthcare Delivery In The Eyes Of Program Managers And Field Staff: A Multi-Site Qualitative Study, Vyshnave Jeyabalan, Elysée Nouvet, Patrick Meier, Lorie Donelle Phd, Rn, Fcan
Publications
Unmanned aerial vehicles (UAVs), also known as drones, have significant potential in the healthcare field. Ethical and practical concerns, challenges, and complexities of using drones for specific and diverse healthcare purposes have been minimally explored to date. This paper aims to document and advance awareness of diverse context-specific concerns, challenges, and complexities encountered by individuals working on the front lines of drones for health. It draws on original qualitative research and data from semi-structured interviews (N = 16) with drones for health program managers and field staff in nine countries. Directed thematic analysis was used to analyze interviews and identify …
The Application Of Drones In Healthcare And Health-Related Services In North America: A Scoping Review, Bradley Hiebert, Elysée Nouvet, Vyshnave Jeyabalan, Lorie Donelle Phd, Rn, Fcan
The Application Of Drones In Healthcare And Health-Related Services In North America: A Scoping Review, Bradley Hiebert, Elysée Nouvet, Vyshnave Jeyabalan, Lorie Donelle Phd, Rn, Fcan
Publications
Using drone aircraft to deliver healthcare and other health-related services is a relatively new application of this technology in North America. For health service providers, drones represent a feasible means to increase their efficiency and ability to provide services to individuals, especially those in difficult to reach locations. This paper presents the results of a scoping review of the research literature to determine how drones are used for healthcare and health-related services in North America, and how such applications account for human operating and machine design factors. Data were collected from PubMed, CINAHL, Scopus, Web of Science, and IEEE Xplore …
Building Implementation Science In Nutrition, Andrea M. Warren, Edward A. Frongillo Jr., Rahul Rawat
Building Implementation Science In Nutrition, Andrea M. Warren, Edward A. Frongillo Jr., Rahul Rawat
Faculty Publications
The field of nutrition has been investing in the development of many nutrition-specific and -sensitive policies and programs aimed at improving population-level malnutrition in all its forms. When there is a need to learn about a new system, programmatic context, or target population to understand how to effectively deploy an intervention to help improve nutrition, it is important to be able to ask a broad range of questions, both in topic and in scope. Our aim is to provide a simple and conceptually clear definition and principles to elaborate the science of implementation for nutrition to distinguish it from other …
Cyber Social Threats 2020 Workshop Meta-Report: Covid-19, Challenges, Methodological And Ethical Considerations, Ugur Kursuncu, Yelena Mejova, Jeremy Blackburn, Amit Sheth
Cyber Social Threats 2020 Workshop Meta-Report: Covid-19, Challenges, Methodological And Ethical Considerations, Ugur Kursuncu, Yelena Mejova, Jeremy Blackburn, Amit Sheth
Publications
Online platforms have been increasingly misused by ill-intentioned actors, affecting our society, often leading to real-world events of social significance. On the other hand, recog-nizing the narratives related to harmful behaviors is challeng-ing due to its complex and sensitive nature. The Cyber SocialThreats Workshop 2020 aimed to stimulate research for thechallenges on methodological and ethical considerations indeveloping novel approaches to analyze online harmful con-versations, concerning social, cultural, emotional, commu-nicative, and linguistic aspects. It provided a forum to bringtogether researchers and practitioners from both academiaand industry in the areas of computational social sciences, so-cial network analysis and mining, natural language process-ing, …
Exploring The Ethical Issues In Research Using Digital Data Collection Strategies With Minors: A Scoping Review, Danica Facca, Maxwell J. Smith, Jacob Shelley, Daniel Lizotte, Lorie Donelle Phd, Rn, Fcan
Exploring The Ethical Issues In Research Using Digital Data Collection Strategies With Minors: A Scoping Review, Danica Facca, Maxwell J. Smith, Jacob Shelley, Daniel Lizotte, Lorie Donelle Phd, Rn, Fcan
Publications
While emerging digital health technologies offer researchers new avenues to collect real-time data, little is known about current ethical dimensions, considerations, and challenges that are associated with conducting digital data collection in research with minors. As such, this paper reports the findings of a scoping review which explored existing literature to canvass current ethical issues that arise when using digital data collection in research with minors. Scholarly literature was searched using electronic academic databases for articles that provided explicit ethical analysis or presented empirical research that directly addressed ethical issues related to digital data collection used in research with minors. …
A Remote-Controlled Robotic System With Safety Protection Strategy Based On Force-Sensing And Bending Feedback For Transcatheter Arterial Chemoembolization, Junqiang Zhou, Ziyang Mei, Jia Miao, Jingsong Mao, Lingyun Wang, Dezhi Wu, Daoheng Sun, Yang Zhao
A Remote-Controlled Robotic System With Safety Protection Strategy Based On Force-Sensing And Bending Feedback For Transcatheter Arterial Chemoembolization, Junqiang Zhou, Ziyang Mei, Jia Miao, Jingsong Mao, Lingyun Wang, Dezhi Wu, Daoheng Sun, Yang Zhao
Publications
Transcatheter arterial chemoembolization (TACE) is the common choice of non-open surgery for hepatocellular carcinoma (HCC) now. In this study, a simple TACE robotic system of 4-degree-of-freedom is proposed to get higher accuracy and stability of the surgery operation and reduce X-ray exposure time of the surgeons. The master-slave control strategy is adopted in the robotic system and a customized sigmoid function is designed to optimize the joystick control of the master-slave robotic control system. A force-sensing module is developed to sense the resistance of the guide wire in linear delivery motion and an auxiliary bending feedback method based on constraint …
Men’S Vasectomy Knowledge, Attitudes, And Information-Seeking Behaviors In The Southern United States: Results From An Exploratory Survey, Ashley L. White, Rachel E. Davis, Deborah Lynn Billings Phd, Emily S. Mann
Men’S Vasectomy Knowledge, Attitudes, And Information-Seeking Behaviors In The Southern United States: Results From An Exploratory Survey, Ashley L. White, Rachel E. Davis, Deborah Lynn Billings Phd, Emily S. Mann
Faculty Publications
Vasectomy is one of the few options men have to manage their reproductive capacity and take on a more equitable role in pregnancy prevention. While the method is underused throughout the United States, the southern states have a lower prevalence rate compared to the rest of the country. Existing survey research does not assess what men know or think about the procedure as a means of understanding why this is the case. We created and conducted an exploratory survey to assess men’s knowledge, attitudes, and information-seeking behaviors about vasectomy in the Southern United States. We used targeted Facebook advertising to …
The Daily Gamecock, Pieces Of Home, August 2020, University Of South Carolina, Office Of Student Media
The Daily Gamecock, Pieces Of Home, August 2020, University Of South Carolina, Office Of Student Media
August
No abstract provided.
Introduction To Big Data Computing For Geospatial Applications, Zhenlong Li, Wenwu Tang, Qunying Huang, Eric Shook, Qingfeng Guan
Introduction To Big Data Computing For Geospatial Applications, Zhenlong Li, Wenwu Tang, Qunying Huang, Eric Shook, Qingfeng Guan
Faculty Publications
The convergence of big data and geospatial computing has brought challenges and opportunities to GIScience with regards to geospatial data management, processing, analysis, modeling, and visualization. This special issue highlights recent advancements in integrating new computing approaches, spatial methods, and data management strategies to tackle geospatial big data challenges and meanwhile demonstrates the opportunities for using big data for geospatial applications. Crucial to the advancements highlighted here is the integration of computational thinking and spatial thinking and the transformation of abstract ideas and models to concrete data structures and algorithms. This editorial first introduces the background and motivation of this …
Recent Advances In Hydrothermal Carbonisation: From Tailored Carbon Materials And Biochemicals To Applications And Bioenergy, Sabina A. Nicolae, Heather Au, Pierpaolo Modugno, Hui Luo, Anthony E. Szego, Mo Qiao, Liang Li, Wang Yin, Hero J. Heeres, Nicole Berge, Maria Magdalena Titirici
Recent Advances In Hydrothermal Carbonisation: From Tailored Carbon Materials And Biochemicals To Applications And Bioenergy, Sabina A. Nicolae, Heather Au, Pierpaolo Modugno, Hui Luo, Anthony E. Szego, Mo Qiao, Liang Li, Wang Yin, Hero J. Heeres, Nicole Berge, Maria Magdalena Titirici
Faculty Publications
Introduced in the literature in 1913 by Bergius, who at the time was studying biomass coalification, hydrothermal carbonisation, as many other technologies based on renewables, was forgotten during the "industrial revolution". It was rediscovered back in 2005, on the one hand, to follow the trend set by Bergius of biomass to coal conversion for decentralised energy generation, and on the other hand as a novel green method to prepare advanced carbon materials and chemicals from biomass in water, at mild temperature, for energy storage and conversion and environmental protection. In this review, we will present an overview on the latest …
The Title Ix Paradox, Emily Suski
The Title Ix Paradox, Emily Suski
Faculty Publications
When Christine Blasey Ford explained to the Senate Judiciary Committee why she had not reported her sexual assault at age fifteen, she captured the struggle of many children who must decide whether to make such reports: “For a very long time, I was too afraid and ashamed to tell anyone the details.” Thousands of sexual assaults happen to children in school each year. Title IX, a potentially powerful civil rights law, should protect them. Title IX’s main purpose is to protect individuals from sex discrimination, including in the form of sexual harassment and assault, in public schools. Yet Title IX …
Front Matter - 2020, Upstate Account
Front Matter - 2020, Upstate Account
University of South Carolina Upstate Student Research Journal
Includes Table of Contents, Award Winners, and more
Femicides In Latin America, Sedrick Ruiz Martinez, Shannon Polchow
Femicides In Latin America, Sedrick Ruiz Martinez, Shannon Polchow
University of South Carolina Upstate Student Research Journal
Femicide is the killing of a woman by a man solely on the account of her gender. It is the ultimate form of gender violence that includes sexual, mental, or physical suffering. It derives from a distorted sense of ownership, hatred, and entitlement from men. Femicides can stem from violent relationships; however, they can be targeted despite having no connection at all to their perpetrator. It has become an indisputable problem throughout Latin America without an end in sight. The purpose of this work is to introduce and identify the underlying factors that contribute to the occurrence of femicides within …
The Power Of The Fan Base: How Mass Media’S Framing Theory Portrays The Heavy Metal Fan Base, Emily Hammond, Shuang Hundley
The Power Of The Fan Base: How Mass Media’S Framing Theory Portrays The Heavy Metal Fan Base, Emily Hammond, Shuang Hundley
University of South Carolina Upstate Student Research Journal
Mass media has been a constant presence in our society. Through discussion of politics and subject matter that affects everyday life, mass media has given us information that has the power to sway public opinion. However, with that power comes consequences that at times would be dismissed by the media, but harmful to groups of people. A perfect example of those consequences branched from a series of accusations made about the heavy metal fan base. In the past few decades, metal heads have had fingers pointed in their direction in the midst of crises across the United States. What is …
Quantitatively Assessed Blood Loss Compared To Visually Estimated Blood Loss In The Early Identification And Treatment Of Post-Partum Hemorrhage, Hannah E. Collier, Ryan Crawford
Quantitatively Assessed Blood Loss Compared To Visually Estimated Blood Loss In The Early Identification And Treatment Of Post-Partum Hemorrhage, Hannah E. Collier, Ryan Crawford
University of South Carolina Upstate Student Research Journal
Nearly one-quarter of all maternal pregnancy-related deaths worldwide are a result of post-partum hemorrhage (PPH) [1]. In the Joint Commission’s Sentinel Event Database, hemorrhage was a causal factor in over half of the cases leading to maternal death or severe morbidity [3]. Between 1993 and 2014, the rate of PPH per 10,000 delivery hospitalizations increased by almost five times, from 4.3 to 21.2 [3]. Using visualization to estimate blood loss is currently the primary method for assessment. However, a new, alternative assessment technique is using quantitative measurement. These two techniques were compared through a literature review. The literature review was …
Does Poverty Rate Increase Terrorism In A Country?: An Analysis From 1970-2019 ★, Sarah E. Distefano, Matthew Placek
Does Poverty Rate Increase Terrorism In A Country?: An Analysis From 1970-2019 ★, Sarah E. Distefano, Matthew Placek
University of South Carolina Upstate Student Research Journal
While terrorism has been a constant product of society, its determinants have been sporadic at best and inconclusive at worst. With the scientific community failing to arrive at a common consensus in reference to poverty as defined by GDP per capita, I hope to find a concrete conclusion by taking a different approach and examining the relationship between poverty rate and terrorism. In order to define the impact of poverty rate on terrorism, I utilized the Quality of Government Index Standard Time Series Dataset and the Global Terrorism Database. Further analysis was conducted by performing an OLS regression on the …
Eadar Canaan Is Garrabost (Between Canaan And Garrabost): Religion In Derick Thomson’S Lewis Poetry, Petra Johana Poncarová
Eadar Canaan Is Garrabost (Between Canaan And Garrabost): Religion In Derick Thomson’S Lewis Poetry, Petra Johana Poncarová
Studies in Scottish Literature
Discusses the treatment of religious belief in the Gaelic poetry of Derick Thomson (1921-2012), from the Outer Hebridean island of Lewis, off the northwest coast of Scotland, surveying Thomson's poems about his encounters with varieties of Presbyterianism, notably the Free Church, and exploring also nuances and religious allusions in poems about his own experience.
Books Noted And Received, Patrick Scott
Books Noted And Received, Patrick Scott
Studies in Scottish Literature
Shorter reviews and notices of recent books in Scottish literature and adjacent disciplines.
Is It Safe For My Child’S Asthma?, Utkarshani Jaimini, Amit Sheth, Krishnaprasad Thirunarayan, Maninder Kalra, Marco Valtorta
Is It Safe For My Child’S Asthma?, Utkarshani Jaimini, Amit Sheth, Krishnaprasad Thirunarayan, Maninder Kalra, Marco Valtorta
Publications
kHealth-Asthma, a personalised digital healthcare framework is developed to address the above shortcomings by continuous monitoring of the child’s digital phenotype, indoor, and outdoor environmental data. The kHealth-Asthma study has recruited 140 children (ongoing) with an aim to complete recruitment of 150 children. The study period is either 1 month or 3 month depending on the choice of the study participant. kHealth-Asthma collects 29 multi-modal parameters leading to 1852 data points per patient per day (i.e. deployment: 1 month:1852*30=55,560 data points per patient and 3 month:1852*90=166,680 data points per patient). The digital phenotype collected using the kHealth-Asthma generates a Digital …
Struggling To Breathe: Covid-19, Protest, And The Lis Response, Amelia N. Gibson, Renate Chancellor, Nicole A. Cooke, Sarah Park Dahlen, Beth Patin, Yasmeen Shorish
Struggling To Breathe: Covid-19, Protest, And The Lis Response, Amelia N. Gibson, Renate Chancellor, Nicole A. Cooke, Sarah Park Dahlen, Beth Patin, Yasmeen Shorish
Faculty Publications
The purpose of this article is to provide a follow up to “Libraries on the Frontlines: Neutrality and Social Justice,” which was published in 2017. It addresses institutional responses to protests and uprising in the spring and summer of 2020 after the deaths of Ahmaud Arbery, Breonna Taylor, and George Floyd—all of which occurred in the context of the global COVID-19 pandemic. The article expands the previous call for libraries to take a stand for Black Lives. We describe the events of 2020 (a global pandemic, multiple murders of unarmed Black people, and the consequent global protests) and responses from …
Lipocalin 2 Induces Neuroinflammation And Blood-Brain Barrier Dysfunction Through Liver-Brain Axis In Murine Model Of Nonalcoholic Steatohepatitis, Ayan Mondal, Dipro Bose, Punnag Saha, Sutapa Sarkar, Ratanesh K. Seth, Diana Kimono, Muayad Albadrani, Mitzi Nagarkatti, Prakash Nagarkatti, Saurabh Chatterjee
Lipocalin 2 Induces Neuroinflammation And Blood-Brain Barrier Dysfunction Through Liver-Brain Axis In Murine Model Of Nonalcoholic Steatohepatitis, Ayan Mondal, Dipro Bose, Punnag Saha, Sutapa Sarkar, Ratanesh K. Seth, Diana Kimono, Muayad Albadrani, Mitzi Nagarkatti, Prakash Nagarkatti, Saurabh Chatterjee
Faculty Publications
BACKGROUND:
Recent clinical and basic research implicated a strong correlation between NAFLD/NASH phenotypes with ectopic manifestations including neuroinflammation and neurodegeneration, but the mediators and critical pathways involved are not well understood. Lipocalin 2 (Lcn2) is one of the important mediators exclusively produced in the liver and circulation during NASH pathology.
METHODS:
Using murine model of NASH, we studied the role of Lcn2 as a potent mediator of neuroinflammation and neurodegeneration in NASH pathology via the liver-brain axis. RESULTS: Results showed that high circulatory Lcn2 activated 24p3R (Lipocalin2 receptor) in the brain and induced the release of high mobility group box …