Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Social and Behavioral Sciences (1115)
- Law (976)
- Medicine and Health Sciences (784)
- Arts and Humanities (564)
- Education (501)
-
- Engineering (443)
- Library and Information Science (390)
- Life Sciences (376)
- Public Health (375)
- Physical Sciences and Mathematics (326)
- Business (278)
- Curriculum and Instruction (197)
- Public Health Education and Promotion (179)
- English Language and Literature (176)
- Nursing (166)
- Education Law (157)
- Chemistry (153)
- Psychology (153)
- Biology (129)
- Communication (114)
- Electrical and Computer Engineering (112)
- Chemical Engineering (111)
- Computer Engineering (100)
- Anthropology (96)
- Mechanical Engineering (91)
- History (88)
- Sports Management (87)
- Music (86)
- Sociology (76)
- Political Science (69)
- Keyword
-
- University of South Carolina (590)
- Faculty Senate (349)
- Sports (139)
- USC (135)
- News (125)
-
- Opinion (124)
- SC (123)
- The Daily Gamecock (123)
- Arts and culture (121)
- South Carolina Library Association (117)
- South Carolina (108)
- Football (100)
- COVID-19 (85)
- Social media (72)
- Baseball (68)
- Technology (67)
- Editorial (65)
- Garnet & Black (65)
- Garnet Media Group (65)
- Student Magazine (65)
- Student Media (65)
- Student Publications (65)
- UofSC (65)
- SEC (64)
- Education (54)
- Music (52)
- NCAA (50)
- Public Health (48)
- Mental health (45)
- Children (44)
- Publication Year
- Publication
-
- Theses and Dissertations (1794)
- Faculty Publications (999)
- Faculty Senate (384)
- Senior Theses (366)
- South Carolina Law Review (365)
-
- The Journal of Law and Education (365)
- Journal of Issues in Intercollegiate Athletics (287)
- October (216)
- February (211)
- September (205)
- April (196)
- March (186)
- Publications (169)
- November (166)
- South Carolina Libraries (157)
- January (150)
- August (111)
- South Carolina Journal of International Law and Business (71)
- Studies in Scottish Literature (71)
- Garnet & Black Magazine (65)
- Journal of the South Carolina Academy of Science (62)
- June (46)
- December (41)
- Faculty and Staff Publications (40)
- Southeastern Environmental Law Journal (40)
- July (37)
- SCIAA Magazine - Legacy & PastWatch (24)
- Under the Dome, McKissick Museum Newsletter (24)
- Clinical Practice in Athletic Training (23)
- Doctor of Nursing Practice Scholarly Projects (23)
- Publication Type
- File Type
Articles 1411 - 1440 of 7222
Full-Text Articles in Entire DC Network
Evaluating The Impact Of Reciprocal Teaching Embedded Within A Web 2.0 Tool Upon Fifth-Grade Students’ Reading Comprehension During Integrated Readers’ Workshop At A Professional Development School, Aisja Jones
Theses and Dissertations
Historical data showed evidence of repeated poor performance on end-of-year (EOY) state tests (South Carolina Department of Education [SCDE], 2017, 2018, 2019). For this study, 12 fifth-grade students read expository text, employed reciprocal teaching strategies, collaborated face to face and online using a Web 2.0 tool during the reading workshop. The purpose of this action research was to evaluate the impact of reciprocal teaching embedded in the Wakelet Curation Tool, a Web 2.0 tool, on fifth-grade students’ reading for comprehension, reading attitudes, and perceptions of the innovation in an integrated reading class at an urban characteristic (Milner et al. 2018) …
Turning Passion Into Action: The Intersection Of Transformational Coaching And A Counter-Narrative Of Black Citizenship, Erica D. Kelley
Turning Passion Into Action: The Intersection Of Transformational Coaching And A Counter-Narrative Of Black Citizenship, Erica D. Kelley
Theses and Dissertations
This action research study explored Black middle school students’ interactions with a high-quality civics curriculum that sought to complicate traditional notions of citizenship; provide authentic opportunities for engagement and participation; center student voices; and foster positive, empowered civic identities. The study also examined whether transformational coaching, with an explicit focus on culturally responsive practices, enhanced one social studies teacher’s ability to implement such a curriculum. Critical race theory and social identity theory illuminated how traditional civics education, rooted in white supremacy, excludes and distorts Black citizenship and civic identities; conversely, both theories informed alternative views of citizenship and identity rooted …
Durability Enhancement Of Anion Exchange Membrane Based Fuel Cells (Aemfcs) And Water Electrolyzers (Aemels) By Understanding Degradation Mechanisms, Noor Ui Hassan
Theses and Dissertations
The past several years have seen remarkable progress in renewable energy sources such as solar and wind, showing excellent efficiency and significant cost reduction. The intermittent nature of renewable resources requires them to be integrated with energy storage systems that can hold or convert this excess energy into other forms. Though batteries have been the most popular, it is also possible to store the energy as chemicals and fuels, such as hydrogen (H2). Hydrogen generation from water electrolysis has been receiving significant attention in recent years. Among the existing water electrolysis technologies, anion exchange membrane electrolyzers (AEMELs) are …
Speculative Pasts: American Historical Fiction In An Age Of Empire, Gregory William Deinert
Speculative Pasts: American Historical Fiction In An Age Of Empire, Gregory William Deinert
Theses and Dissertations
This study identifies a new generic form termed here the “Speculative Historical Novel” within contemporary American fiction. The works that Speculative Pasts collect all agonize over the erasure of the past, and question how we can incorporate history into the present while accepting that full recuperation may be impossible. In their emphasis on the erasure of the past, these novels trace the manifold silences created by the imperial conquest of the New World and articulate how this past continues to structure the lived experiences of everyone on this continent.
This speculation is, on the one hand, necessarily suppositional. When faced …
Embodied Participation In Digital Publics: Somnambulance, Surveillance, And The Construction Of Identity, Adam S. Padgett
Embodied Participation In Digital Publics: Somnambulance, Surveillance, And The Construction Of Identity, Adam S. Padgett
Theses and Dissertations
In our current information landscape, routine surveillance has changed the nature of rhetorical engagement in public spheres. Scholarship in publics theory have done productive work to map out the complex field of discursive participation. Michael Warner has demonstrated how, through the circulation of common texts, people no longer have to be in public in order to participate in publics. However, in the wake of ubiquitous surveillance, this focus on publicness has offered little attention to privacy in publics theory. I argue that legal and postmodern theories of bodies-as-texts is problematic for reading and writing bodies online. Intersecting with embodiment and …
Belonging In Context: An Exploration Of Sense Of Belonging Among College Students, Ladonna L. Gleason
Belonging In Context: An Exploration Of Sense Of Belonging Among College Students, Ladonna L. Gleason
Theses and Dissertations
Feeling a sense of belonging is essential to human health and functioning and has been well documented in the literature. However, questions of context remain. Research in belonging has focused on social aspects of belonging, leaving broader contextual frames unexplored. There has been little work in identifying and differentiating the contexts in which belonging is experienced or in developing an understanding of how the experience of belonging differs across contexts. Current belonging theory lacks this important contextual perspective that could inform the ways in which belonging is constructed and reconstructed through disruption. With the advent of the COVID-19 pandemic, new …
When And Why Targeted Products For Underserved Consumers Backfire, Ruoou Li
When And Why Targeted Products For Underserved Consumers Backfire, Ruoou Li
Theses and Dissertations
As the demand for creating and embracing a diverse marketplace increases, marketing strategies that over-generalize the needs of different consumer groups are no longer viable. Thus, many brands and companies have begun offering inclusive products that accommodate the specific needs of historically underserved consumers (e.g., women, people of color). One important question for marketers to answer is how these inclusive products should be promoted to appeal to these previously undervalued consumers. While prior research suggests that consumers will favor products with more explicit descriptions of the target consumer (i.e., blatant targeting) because doing so makes the targeted identity salient, I …
Urban Flooding Accelerates The Affordable Housing Shortage: A Case Study In Columbia, South Carolina, Mary Hannah Lindsay
Urban Flooding Accelerates The Affordable Housing Shortage: A Case Study In Columbia, South Carolina, Mary Hannah Lindsay
Theses and Dissertations
The state of South Carolina stands at the corner where climate change and the housing crisis meet. The affordable housing stock across South Carolina continues to deplete as its major cities experience urban flooding events due to outdated and weakened infrastructure, compounded by an intensification of storm systems brought on by a changing climate. Lower income communities are forced to accept lesser living conditions and less resilient housing options because these options are more affordable. Renters are often met with more challenges when navigating disaster recovery compared to homeowners. Using a case study established in Columbia, South Carolina of the …
Exploring African American Girlhood Perceptions And Experiences Of Self Esteem, Monica Wade
Exploring African American Girlhood Perceptions And Experiences Of Self Esteem, Monica Wade
Theses and Dissertations
Furthering the cultural competence of counselors around emotional wellness for minority groups, this research explored the intersectionality of race and gender through counter storytelling of experiences of Black girlhood that are often not told. To fill the existing gap in literature describing perceptions of emotional wellness, I explored African American adolescent girls perceptions and experiences of self esteem for girls who participated in an empowerment organization called Dream Girls. This qualitative study used a phenomenological analysis to gain understanding of the influences that impact the way these adolescents understand themselves.
Magnetic Field Directed Self-Assembly Of Colloidal Nanoparticles Via Extreme Field Gradients Of Magnetic Recording Media, Abdul Rahman Mohtasebzadeh
Magnetic Field Directed Self-Assembly Of Colloidal Nanoparticles Via Extreme Field Gradients Of Magnetic Recording Media, Abdul Rahman Mohtasebzadeh
Theses and Dissertations
Magnetic nanoparticles have been extensively studied over the last half century and continue to sustain interest due to their potential use in different fields. This research explores Magnetic Field Directed Self-Assembly of magnetic nanoparticles using a magnetic disk drive. The magnetic fields generated by the bits in a magnetic disk drive have rapidly changing field gradients that can self-assemble magnetic nanoparticles into various shapes. We demonstrate the ability to record and read field gradients on a commercial disk drive medium and to use monodisperse iron oxide nanoparticles to achieve self-assembly. We use image analysis techniques to quantify parameters related to …
Learning To Automate Follow-Up Question Generation Using Process Knowledge For Depression Triage On Reddit Posts, Shrey Gupta, Anmol Agarwal, Manas Gaur, Kaushik Roy, Vignesh Narayanan, Ponnurangam Kumaraguru, Amit Sheth
Learning To Automate Follow-Up Question Generation Using Process Knowledge For Depression Triage On Reddit Posts, Shrey Gupta, Anmol Agarwal, Manas Gaur, Kaushik Roy, Vignesh Narayanan, Ponnurangam Kumaraguru, Amit Sheth
Publications
Conversational Agents (CAs) powered with deep language models (DLMs) have shown tremendous promise in the domain of mental health. Prominently, the CAs have been used to provide informational or therapeutic services (e.g., cognitive behavioral therapy) to patients. However, the utility of CAs to assist in mental health triaging has not been explored in the existing work as it requires a controlled generation of follow-up questions (FQs), which are often initiated and guided by the mental health professionals (MHPs) in clinical settings. In the context of `depression', our experiments show that DLMs coupled with process knowledge in a mental health questionnaire …
Muscular Strength And Carotid Intima-Media Thickness In Physically Fit Young Adults: The Chief Atherosclerosis Study, Gen-Min Lin, Kun-Zhe Tsai, Yun-Chen Chang, Wei-Chun Huang, Xuemei Sui M.D., M.P.H., Ph.D., Carl J. Lavie
Muscular Strength And Carotid Intima-Media Thickness In Physically Fit Young Adults: The Chief Atherosclerosis Study, Gen-Min Lin, Kun-Zhe Tsai, Yun-Chen Chang, Wei-Chun Huang, Xuemei Sui M.D., M.P.H., Ph.D., Carl J. Lavie
Faculty Publications
Background: Greater muscular strength (MusS) has been found to have an inverse association with subclinical atherosclerosis in children, as well as with mortality from cardiovascular diseases (CVDs) in middle-aged and elderly individuals. However, the association of the degree of MusS with atherosclerosis may differ by sex and has not been clarified in young adults. Methods and Results: A total of 1021 Taiwanese military personnel, aged 18–40 years, participated in annual health examinations in 2018–2020. MusS was separately assessed by 2-min push-up and 2-min sit-up numbers. Subclinical atherosclerosis was measured by the left carotid bulb intima–media thickness (cIMT) using high-resolution ultrasonography. …
Towards Efficient Scoring Of Student-Generated Long-Form Analogies In Stem, Thilini Wijesiriwardene, Ruwan Wickramarachchi, Valerie L. Shalin, Amit P. Sheth
Towards Efficient Scoring Of Student-Generated Long-Form Analogies In Stem, Thilini Wijesiriwardene, Ruwan Wickramarachchi, Valerie L. Shalin, Amit P. Sheth
Publications
Switching from an analogy pedagogy based on comprehension to analogy pedagogy based on production raises an impractical manual analogy scoring problem. Conventional symbol-matching approaches to computational analogy evaluation focus on positive cases, and challenge computational feasibility. This work presents the Discriminative Analogy Features (DAF) pipeline to identify the discriminative features of strong and weak long-form text analogies. We introduce four feature categories (semantic, syntactic, sentiment, and statistical) used with supervised vector-based learning methods to discriminate between strong and weak analogies. Using a modestly sized vector of engineered features with SVM attains a 0.67 macro F1 score. While a semantic feature …
Genome-Wide Association Analyses Of Physical Activity And Sedentary Behavior Provide Insights Into Underlying Mechanisms And Roles In Disease Prevention, Zhe Wang, Andrew Emmerich, Nicolas J. Pillon, Tim Moore, Daiane Hemerich, Marilyn C. Cornelis, Eugenia Mazzaferro, Siacia Broos, Tarunveer S. Ahluwalia, Traci M. Bartz, Amy R. Bentley, Lawrence F. Bielak, Mike Chong, Audrey Y. Chu, Diane Berry, Rajkumar Dorajoo, Nicole D. Dueker, Elisa Kasbohm, Bjarke Feenstra, Mary F. Feitosa, Mark A. Sarzynski Ph.D., Faha, Facsm, Et. Al.
Genome-Wide Association Analyses Of Physical Activity And Sedentary Behavior Provide Insights Into Underlying Mechanisms And Roles In Disease Prevention, Zhe Wang, Andrew Emmerich, Nicolas J. Pillon, Tim Moore, Daiane Hemerich, Marilyn C. Cornelis, Eugenia Mazzaferro, Siacia Broos, Tarunveer S. Ahluwalia, Traci M. Bartz, Amy R. Bentley, Lawrence F. Bielak, Mike Chong, Audrey Y. Chu, Diane Berry, Rajkumar Dorajoo, Nicole D. Dueker, Elisa Kasbohm, Bjarke Feenstra, Mary F. Feitosa, Mark A. Sarzynski Ph.D., Faha, Facsm, Et. Al.
Faculty Publications
Although physical activity and sedentary behavior are moderately heritable, little is known about the mechanisms that influence these traits. Combining data for up to 703,901 individuals from 51 studies in a multi-ancestry meta-analysis of genome-wide association studies yields 99 loci that associate with self-reported moderate-to-vigorous intensity physical activity during leisure time (MVPA), leisure screen time (LST) and/or sedentary behavior at work. Loci associated with LST are enriched for genes whose expression in skeletal muscle is altered by resistance training. A missense variant in ACTN3 makes the alpha-actinin-3 filaments more flexible, resulting in lower maximal force in isolated type IIA muscle …
September 7, 2022 General Faculty Minutes, University Of South Carolina
September 7, 2022 General Faculty Minutes, University Of South Carolina
Faculty Senate
No abstract provided.
Solving The "King Lear Problem", Benjamin Means
Solving The "King Lear Problem", Benjamin Means
Faculty Publications
In Shakespeare’s play, King Lear, an aging ruler relinquished control to two of his three daughters. The succession failed miserably, destroying his family and destabilizing his kingdom. King Lear shows why few family businesses survive beyond three generations. Understanding Lear’s failure is crucial to avoiding Lear’s fate, whether the family business in question is a monarchy, a media empire, or a hardware store. The conventional wisdom is that Lear gave away his kingdom too soon and left himself vulnerable to predatory heirs. This has been referred to as the “King Lear Problem.”
The conventional wisdom is wrong. Lear’s succession plan …
The Daily Gamecock, Welcome Home, August 2022, University Of South Carolina, Office Of Student Media
The Daily Gamecock, Welcome Home, August 2022, University Of South Carolina, Office Of Student Media
August
No abstract provided.
Populist Syndrome And Nonmarket Strategy, Daniel J. Blake, Stanislav Markus, Julio Martinez-Suarez
Populist Syndrome And Nonmarket Strategy, Daniel J. Blake, Stanislav Markus, Julio Martinez-Suarez
Faculty Publications
Although recognized as a defining feature of the current political era, populism and its implications for non-market strategy remain undertheorized. We offer a framework that (a) conceptualizes populism and its progression over time; (b) outlines the risks populism generates for firms; and (c) theorizes effective nonmarket strategies under populism. Our framework anchors the political risk profile of populism in three interdependent elements: anti-establishment ideology, de-institutionalization, and short-term policy bias. These elements jointly shape the policymaking dy-namics and institutional risks for firms under populism. Our analysis shows how firms can calibrate two nonmarket strategies – political ties and corporate social responsibility …
Gender Disparities In Increased Parenting Time During The Covid-19 Pandemic: A Research Note, Jennifer Augustine, Kate Prickett
Gender Disparities In Increased Parenting Time During The Covid-19 Pandemic: A Research Note, Jennifer Augustine, Kate Prickett
Faculty Publications
Public health measures aimed at curbing the transmission of COVID-19 increased parenting responsibilities during the early stages of the pandemic. This research note examines time-use data from the American Time Use Surveys to provide several fresh insights as to how mothers took on a disproportionate share of this responsibility compared to fathers during this period. First, the gender gap in total parenting time narrowed by 18%. Meanwhile, the gender disparity in time in educational activities increased by 113% and was not explained by changes in mothers’ labor force participation. Mothers also took on 20% more time in secondary caregiving compared …
Imposter Phenomenon Progression And Intersectionality Among Undergraduate Students, Asia Johnson
Imposter Phenomenon Progression And Intersectionality Among Undergraduate Students, Asia Johnson
USC Aiken Psychology Theses
Previous research indicates that women, students, and racial ethnic minorities experience Imposter Phenomenon (IP) at higher rates when compared to their counterparts. Anxiety and depression have also been linked to IP at seemingly high rates, as the construct overlaps with aspects of both disorders. The amount of time at a collegiate institution has not been examined in relation to IP, with little research emphasizing the effect of a predominately White campus climate on African American undergraduate students. The current study seeks to full these gaps in the literature, with an additional investigation of the role intersectionality plays. The results of …
Compliance With Ostracism: How Excluding A Member Of A Despised Outgroup Affects Psychological Need Satisfaction, Emma Nettles
Compliance With Ostracism: How Excluding A Member Of A Despised Outgroup Affects Psychological Need Satisfaction, Emma Nettles
USC Aiken Psychology Theses
Ostracism is a social process through which individuals are excluded or ignored (Williams, 1998). While recent research has slowly shifted toward the perpetrators of ostracism, relative to the targets, there is still little research on the effects of complying with ostracism. While previous research suggests engaging in ostracism leads to negative affect and thwarted need satisfaction, ostracism was directed toward an otherwise underserving target (Legate et al., 2013). The current research examined the effects of being instructed to ostracize a member of a despised outgroup on affect and need satisfaction. Seventy-one participants were recruited to play Cyberball, in which they …
Examining Dehumanization Of Individuals With Schizophrenia, Brianna Drake
Examining Dehumanization Of Individuals With Schizophrenia, Brianna Drake
USC Aiken Psychology Theses
Objective: Previous literature examines dehumanization of marginalized groups; though, most of this work focuses on ethnic and racial groups. Currently, there is a gap in the literature examining the extent to which people with mental illness are dehumanized. This study examined whether people with schizophrenia are dehumanized (relative to other marginalized groups, such as drug addicts). Furthermore, this research will investigate if using “person-first” language can attenuate dehumanization.
Method: Participants (n = 310) were recruited from Amazon Mechanical Turk to complete a measure of dehumanization and demeaning needs for each of the nine targets (i.e., self, close friend, lawyer, elderly, …
Public Perceptions Of Police Use Of Force: Does Officer Race Matter?, Diamond G. Pilgrim
Public Perceptions Of Police Use Of Force: Does Officer Race Matter?, Diamond G. Pilgrim
USC Aiken Psychology Theses
Objective: The purpose of the current study was to examine the effects of police officer as well as suspect race on U.S.residents’ perceptions of police use of force.
Method: Participants were randomly assigned one of four vignettes describing an encounter between either a Black or White police officer and a Black or White robbery suspect. Suspect race and officer race were manipulated so that participants received a vignette involving pairings of a White officer with a Black suspect; a White officer with a White suspect; a Black officer, White suspect or a Black officer and suspect. Participants were then surveyed …
Table Of Contents - 2022, Usc Upstate Account
Table Of Contents - 2022, Usc Upstate Account
University of South Carolina Upstate Student Research Journal
- The Editorial Board, ii
- Are Times A-Changin’? Exploring Current Perceptions of Individuals Based on Sexual and Relationship Orientations, 1
Leah Howard and Kenneth Barideaux - The Social Cognitive Model of Leadership Perceptions: Proposing a Dynamic, Integrated Theory of Leadership Identification and Appraisal, 10 Leah Howard and Justin Travis
- Femininity as Disability in Sylvia Plath's The Bell Jar, 18
Shae Kirkus and Monika Shehi Herr - The Minor Fall, the Major Lift? College Students Do Not Report Listening to Mood-Congruent Music, 22
Hannah Leonhardt, James Bunde, and Andrew Beer - The Boy from 6B: How Only Murders in the Building Created Groundbreaking …
Securing Information On A Web Application System To Facilitate Online Blood Donation Booking, Hrishitva Patel
Securing Information On A Web Application System To Facilitate Online Blood Donation Booking, Hrishitva Patel
Faculty Publications
Blood donation has saved many lives in the past. According to statistics presented by the American Red Cross, a patient is in need of a blood transfusion every two seconds. There are many benefits that arise from blood donation to both the donor and the blood recipients. With blood donation, cancer patients, people involved in accidents, or those battling diseases that require blood donation have access to enough blood to sustain their survival. There is a need to digitize the blood donation booking to facilitate blood donation across the United States, and ensure patients in need of blood, receive their …
Covid Information And Masking Behaviors In U.S. Adolescents: Findings From The Adolescent Brain Cognitive Development (Abcd) Study, Jason M. Nagata, Kyle T. Ganson, Jingyi Liu, Khushi P. Patel, Josephine C. Tai, Stuart B. Murray, Kirsten Bibbins-Domingo
Covid Information And Masking Behaviors In U.S. Adolescents: Findings From The Adolescent Brain Cognitive Development (Abcd) Study, Jason M. Nagata, Kyle T. Ganson, Jingyi Liu, Khushi P. Patel, Josephine C. Tai, Stuart B. Murray, Kirsten Bibbins-Domingo
Publications
Adolescents are particularly vulnerable to health misinformation and are at risk for suboptimal adherence to protective health behaviors in the COVID-19 pandemic. Guided by factors consistent with the theories of planned behavior and rumor transmission, this study sought to analyze the impact of multiple information sources, including social media, television media, internet and parental counseling, on masking behaviors in adolescents. Responses from the December 2020 COVID-19 survey, representing 4,106 U.S. adolescents ages 12-14 from the Adolescent Brain Cognitive Development Study (ABCD) were analyzed. The majority of parents (61.1%) reported counseling their children on the importance of wearing masks all the …
Social Life Of Females With Persistent Covid-19 Symptoms: A Qualitative Study, Atefeh Aghaei, Ran Zhang, Slone Taylor, Cheuk-Chi Tam, Chih-Hsiang Yang, Xiaoming Li Ph.D., Shan Qiao Ph.D.
Social Life Of Females With Persistent Covid-19 Symptoms: A Qualitative Study, Atefeh Aghaei, Ran Zhang, Slone Taylor, Cheuk-Chi Tam, Chih-Hsiang Yang, Xiaoming Li Ph.D., Shan Qiao Ph.D.
Faculty Publications
Persistent COVID-19 symptoms (long COVID) may bring challenges to long haulers' social lives. Females may endure more profound impacts given their special social roles and existing structural inequality. This study explores the effects of long COVID on the social life of female long haulers. We conducted semi-structured interviews via Zoom between April and June 2021 with 15 female long haulers in the United States, purposely recruited from Facebook and Slack groups and organization websites related to long COVID. Interviews were audio-recorded and transcribed verbatim with consent. The interview data were managed using MAXQDA and examined by thematic analysis. Long COVID …
Mir-489 Confines Uncontrolled Estrogen Signaling Through A Negative Feedback Mechanism And Regulates Tamoxifen Resistance In Breast Cancer, Mithil Soni, Ozge Saatci, Gourab Gupta, Yogin Patel, Manikanda Raja Keerthi Raja, Jie Li, Xinfeng Liu, Peisheng Xu Ph.D., Hongjun Wang, Daping Fan, Ozgur Sahin, Hexin Chen
Mir-489 Confines Uncontrolled Estrogen Signaling Through A Negative Feedback Mechanism And Regulates Tamoxifen Resistance In Breast Cancer, Mithil Soni, Ozge Saatci, Gourab Gupta, Yogin Patel, Manikanda Raja Keerthi Raja, Jie Li, Xinfeng Liu, Peisheng Xu Ph.D., Hongjun Wang, Daping Fan, Ozgur Sahin, Hexin Chen
Faculty Publications
Approximately 75% of diagnosed breast cancer tumors are estrogen-receptor-positive tumors and are associated with a better prognosis due to response to hormonal therapies. However, around 40% of patients relapse after hormonal therapies. Genomic analysis of gene expression profiles in primary breast cancers and tamoxifen-resistant cell lines suggested the potential role of miR-489 in the regulation of estrogen signaling and development of tamoxifen resistance. Our in vitro analysis showed that loss of miR-489 expression promoted tamoxifen resistance, while overexpression of miR-489 in tamoxifen-resistant cells restored tamoxifen sensitivity. Mechanistically, we found that miR-489 is an estrogen-regulated miRNA that negatively regulates estrogen receptor …
Latent Class Analysis Of Polysubstance Use And Sexual Risk Behaviors Among Men Who Have Sex With Men Attending Sexual Health Clinics In Mexico City, Rosibel Rodríguez-Bolaños, Ricardo Baruch-Dominguez, Edna Aril, Elsa Yunes-Díaz, Leonor Rivera-Rivera, Lizeth Cruz-Jiménez, Jim F. Thrasher Ph.D., Ma, Ms, Alan G. Nyitray, Eduardo Lazcando-Ponce
Latent Class Analysis Of Polysubstance Use And Sexual Risk Behaviors Among Men Who Have Sex With Men Attending Sexual Health Clinics In Mexico City, Rosibel Rodríguez-Bolaños, Ricardo Baruch-Dominguez, Edna Aril, Elsa Yunes-Díaz, Leonor Rivera-Rivera, Lizeth Cruz-Jiménez, Jim F. Thrasher Ph.D., Ma, Ms, Alan G. Nyitray, Eduardo Lazcando-Ponce
Faculty Publications
Men who have sex with men (MSM) are more likely to use drugs and other substances compared to their heterosexual peers. No studies have evaluated patterns of substance use among MSM adults in Mexico. We used latent class analysis (LCA) to identify MSM subgroups with specific substance use patterns and their associations with sexual behaviors. Methods: Data from 1850 adult MSM were collected at HIV clinics in Mexico City between September 2018 and December 2019. The structural equation modeling approach was used to estimate a LC model to identify patterns of substance use by self-report of substance use (i.e., cigarette …
Nothing Ventured, Nothing Gained: A Meta-Analysis Of Ceo Overconfidence, Strategic Risk Taking, And Performance, Barbara Burkhard, Charlotta Sirén, Marc Van Essen, Dietmar Grichnik, Dean A. Shepherd
Nothing Ventured, Nothing Gained: A Meta-Analysis Of Ceo Overconfidence, Strategic Risk Taking, And Performance, Barbara Burkhard, Charlotta Sirén, Marc Van Essen, Dietmar Grichnik, Dean A. Shepherd
Faculty Publications
Although overconfidence is acknowledged as one of the most common managerial decision-making biases, much uncertainty remains about its implications for firm performance. To resolve this uncertainty, we investigate how and why CEO overconfidence is related to firm performance using meta-analytic techniques on a sample of 199 studies. In particular, relying on behavioral decision theory, we develop alternative hypotheses regarding the impact of CEO overconfidence on firm performance. Contrary to the conventional belief that CEO overconfidence is detrimental, this study reveals that CEO overconfidence is, on average, beneficial for firm performance. Drawing on recent refinements of upper echelons theory and theoretical …