Digital Commons Network^™

Screening For Prediabetes In The Inpatient Setting, Mikayla Jordan Moore

Doctor of Nursing Practice Scholarly Projects

Problem Statement: Many patients that utilize the hospital system do not see a primary care provider and, therefore, miss important screenings. The hospital system can provide convenient screenings, or screenings conducted whenever a patient encounters the health system regardless of their chief complaint (Obinwa et al., 2020).

Purpose: Determine whether convenient prediabetes screenings administered to admitted patients on an Intermediate Critical Care Unit (ICCU) detect prediabetes at a higher rate than no formal screenings.

Methods: Participants will be sampled from those admitted to an intermediate critical care unit at a large acute-care facility.

Inclusion Criteria: Any adult patient (>18 …

Overview Of The Clpsych 2022 Shared Task: Capturing Moments Of Change In Longitudinal User Posts, Adam Tsakalidis, Jenny Chim, Iman Munire Bilal, Ayah Zirikly, Dana Atzil-Slonim, Federico Nanni, Philip Resnik, Manas Gaur, Kaushik Roy, Becky Inkster, Jeff Leintz, Maria Liakata

Publications

We provide an overview of the CLPsych 2022 Shared Task, which focusses on the automatic identification of Moments of Change in longitudinal posts by individuals on social media and its connection with information regarding mental health . This year's task introduced the notion of longitudinal modelling of the text generated by an individual online over time, along with appropriate temporally sensitive evaluation metrics. The Shared Task consisted of two subtasks: (a) the main task of capturing changes in an individual's mood (drastic changes-`Switches'- and gradual changes -`Escalations'- on the basis of textual content shared online; and subsequently (b) the sub-task …

Berbamine Enhances The Efficacy Of Doxorubicin Treatment For Breast Cancer In Vitro And In Vivo, Kristina G. Borglum

Senior Theses

Doxorubicin (Dox) is a commonly used chemotherapy drug for treating breast cancer. While it is very effective, the main limitation of Dox treatment is subsequent cytotoxicity. Berbamine dihydrochloride (BBM) is a natural benzylisoquinoline alkaloid that is extracted from the plant, Berbaris amurensis. It has been widely used in traditional medicine to treat individuals with inflammatory diseases for many centuries. It has already been shown that combining BBM with Dox synergistically enhances the efficacy of Dox treatment on breast cancer in vitro. To eventually translate these findings into a clinical setting, this study aims to explore this therapeutic potential in vivo …

Applying Bostock: The Queer Case Against Public Single-Sex Schooling, Robert Blake Watson

The Journal of Law and Education

No abstract provided.

Nutrition Facts Label Use Among U.S. Adolescents, Jennifer Beth Mandelbaum

Theses and Dissertations

Despite the promise of Nutrition Facts label (NFL) use as a population-level intervention with broad reach, few studies have examined determinants of adolescents’ NFL use, and how this label use may be associated with nutrition behaviors. This study used data from the International Food Policy Study, an online cross-sectional survey of trends in dietary patterns and policy-relevant behaviors in the U.S. and five other countries. First, this study examined 1) whether NFL use was associated with healthy eating efforts and 2) whether there were sociodemographic differences in NFL use among U.S. adolescents. Results demonstrated that NFL use was positively associated …

Achieving Sustainability In Urban Transit And High-Occupancy Vehicle Systems Through Emerging Technologies And Operations, Ruixiao Sun

Theses and Dissertations

It is critical to reduce road transportation emissions, as it is the major source contributing to greenhouse gas emissions (GHGs) and air pollution. However, the increasing travel demand due to the rise of population and economy makes the task challenging. Mathematically, road transportation emissions can be minimized in the manner of reducing total vehicle miles traveled (VMT) and lowering vehicle emission rate. Many strategies have been proven viable for achieving transportation sustainability. For example, the total VMT can be reduced by switching low-occupancy transportation modes (i.e., driving alone) to high-occupancy transportation modes (i.e., public transit, ridesharing). The development of alternative-fuel …

Quasi-Property No More: "Human Heritage" As A New Legal Status For The Dead, Alida B. Soileau

South Carolina Law Review

No abstract provided.

Investigating The Impact Of Endothelial Dysfunction And Aging On Vascular Remodeling Using Mouse Models, Liya Du

Theses and Dissertations

Endothelial dysfunction, characterized by a reduction in the bioavailability of nitric oxide (NO), is a major factor in the initiation and progression of atherosclerosis, an age-related chronic inflammatory process in the arterial wall and the leading cause of mortality and morbidity globally. A better understanding of alterations in vascular structure and function associated with endothelial dysfunction can facilitate the early detection of atherosclerosis and the development of potential pharmaceutical interventions. This study aims to clarify the impact of endothelial dysfunction in conjunction with aging on the microstructure of aortic extracellular matrix (ECM) and to elucidate the relationship between microstructural adaptation …

There’S Action In Silence: An Action Research Study On The Impacts Of Diverse Narratives In An Advanced Placement United States Government Class, Ashley Kristen Wright

Theses and Dissertations

In this action research study, I facilitated and evaluated student exposure to politically, socially, and economically diverse source material within my Advanced Placement United States Government classroom, seeking to resolve students’ apparent disconnect from experiences that differ from their own, which had made connections to topics like civil rights challenging to grasp. Because the supplemental material I had chosen for my government classes failed to provide opposing narratives for my students to make these connections, this study arose as a way to research and ultimately correct this problem from within my government classroom.

Over the course of a semester, I …

Orthographic Knowledge And Phonological Awareness In Children With Speech Sound Disorder, Anna Marie Ehrhorn

Theses and Dissertations

Speech sound disorder (SSD) puts children at risk for word reading difficulties but does not guarantee them. Research on early literacy skills in children with SSD has primarily focused on phonological awareness due to speech sound deficits associated with SSD. Researchers have begun to examine multiple factors beyond phonological awareness that may impact word reading and spelling development. Orthographic knowledge is another essential factor understudied in children with SSD. Previous research has shown that orthographic properties of words influence phonological awareness performance in skilled readers and children with reading difficulties. No known previous studies have examined whether orthography influences phonological …

Histomechanical Compatibility Of Coronary Artery Bypass Grafts, Colton J. Kostelnik

Theses and Dissertations

Coronary artery disease is a localized form of atherosclerosis that can severely restrict blood flow to the heart often requiring a surgical intervention known as coronary artery bypass grafting (CABG) to reestablish perfusion to this essential circulation. To some extent, the selection of the autograft tissue is at the surgeon’s discretion with factors such as stenosis location and the existing tissue’s pathological state contributing to a choice that could be deterministic in surgical outcomes. Many post-operative complications and premature graft failures originate from graft-target tissue incompatibilities and altered blood flow patterns. We hypothesize that mechanical mismatching between the graft material …

Uncovering The Diverse Roles Of The Human Cst (Ctc1-Stn1-Ten1) Complex In Resolving Genomic Stress, Percy Logan Schuck

Theses and Dissertations

The CST (CTC1-STN1-TEN1) complex is a heterotrimeric single-stranded DNA binding protein known to stimulate polymerase α-primase (Pol α) and promote telomere length regulation, genome-wide DNA replication and double strand break repair. However, much of its cellular function remains unknown. The focus of my dissertation work was to uncover novel roles of CST in DNA stress response pathways. In particular, my work relates to understanding the function of CST in sister chromatid cohesion (SCC) and base excision repair (BER) as well as characterizing CST protein interactions. SCC is established following DNA replication by loading of the cohesion complex, which encircles replicated …

The Effects Of Project-Based Game Development On Student Learning And Attitudes: Action Research In An 8Th Grade Introductory Computer Science Course, Theodore G. Jenks

Theses and Dissertations

The purpose of this action research was to implement a digital game development project and describe its effects on the performance and attitudes of eighth-grade students in a required computer science course at South Carolina School District Alpha. The following research questions were explored: (1) How does the game development project impact participants’ ability to analyze and develop algorithms? (2) What is the effect of the game development project on participants’ attitudes toward computer science? and (3) What is the relationship between participants’ attitudes toward computer science and their performance?

There were 28 participants composed of students in a science, …

An Intersectional Lens To Covid-19: Promoting Youth Well-Being In The Midst Of Social-Political Stressors, Magdalena S. Moskal

Theses and Dissertations

Guided by interpretative phenomenological methodology and intersectionality theory, this thesis aims to uncover the mental health experiences of youth surrounding the COVID-19 pandemic. This study also seeks to situate these experiences with the subsequent stressors that young people face in the current social-political context (e.g., witnessing trauma in the media, uprisings to address racism and the resulting backlash, rhetoric of the 2020 presidential election). Furthermore, this thesis aims to give insight and voice how intersectionality shapes the COVID-19-related experiences of youth in South Carolina. Data was collected through semi-structured interviews with 23 participants aged 16-21 years old in South Carolina. …

Identifying And Understanding Factors Which Affect Persistence In Academically At-Risk Minority Prelicensure Nursing Students: An Action Research Study, Christina L.K. Eaton

Theses and Dissertations

Increased representation of minority groups is imperative for professions like nursing and education. With the growing rate of minority racial and ethnic groups within the United States, there should be corresponding changes within these professions, however there is not. This action research study seeks to explore the factors that affect persistence in academically at-risk minority nursing students at a small Midwestern Christian University. The main research question for this study asks, “What factors do at-risk minority nursing students identify as affecting their ability to persist in our nursing program?” The use of Urie Bronfenbrenner’s Social Ecological Model and Critical Theory …

Genomic Analysis Workflows To Identify Mutational Signatures And Structural Variations In Ovcar8 Cells And Rad51d-Deficient Mouse Embryonic Fibroblasts, Manli Yang

Theses and Dissertations

Specific genomic profiles associated with exposure to DNA damaging agents have been identified in cancer related genes, revealing that mutational patterns can be carcinogen- specific. However, there have been limited efforts to demonstrate similar clear relationships for endogenous mutational processes. One endogenous source of mutations is contamination of the deoxynucleotide pool with damaged bases that, if incorporated into DNA, cause mutations.

The Catalog of Somatic Mutations In Cancer (COSMIC) represents an international effort to characterize mutations in cancer. A mutational signature is the pattern of mutations generated by a mutational process. Each mutational process contains two parts: DNA damage and …

Monitoring Titanium Dioxide Engineered Particles In Rural And Urban Surface Waters, Md Mahmudun Nabi

Theses and Dissertations

Quantifying and characterizing engineered particles in environmental systems is key for assessing their risk but remains challenging and requires the distinction between natural and engineered particles. The Ph.D. dissertation research described in this thesis contributes to the current attempts to improve environmental nanoparticle analysis and better understand nanoparticle behavior in natural systems, with the focus being on natural streams, and the application of single particle inductively coupled plasma-time of flight-mass spectrometry (SP-ICP-TOF-MS) for distinguishing and tracing the origins of environmental nanoparticles. The objective of this dissertation is to characterize and quantify the concentrations of titanium dioxide engineered particles in urban …

Gis Analysis Of Housing Delinquency After Repeated Flooding In Horry County, South Carolina, Andrew White

Theses and Dissertations

How communities react and change after disaster has been well-studied in recent decades. Knowledge around time scales, spatial scales, and specific facets of the built environment, such as housing recovery, have all developed largely around the opportunities that disasters have provided in understanding societal functions. This research has given policy makers and institutions insights into shortcomings of disaster specific recoveries, but these shortcomings are generalized beyond the scope of the originally studied areas. This thesis adapts this body of knowledge to a GIS methodology to help localize understanding to the coastal South Carolina context of Horry County. This low-lying area …

The Binge Viewing Index: Creating And Testing A New Measure, Larry J. Webster Jr.

Theses and Dissertations

Television Binge Viewing is a media consumption behavior that is in its research infancy. To date, researches have used a dichotomous variable to measure binge viewing. That measure is based on operationalizing binge viewing as having watched two to six episodes of the same television program in one sitting. This research project created and applied a continuous measure by creating the Binge Viewing Index (BVI), which is based on the duration (number of episodes) and the frequency (weekly average) of binge viewing sessions. These dimensions are structured similarly to measures for binge drinking. A national survey demonstrated the intensity of …

Cocreating A Strength-Based Behavioral Intervention Plan With Twice-Exceptional Students: A Youth Participatory Action Research Approach, Kristy L. Garrett

Theses and Dissertations

Twice-exceptional students are dually identified as academically gifted and talented and learning or medically disabled. These students face greater challenges to success in school and often have social and emotional issues that require accommodations and supports beyond those available in the general classroom. These students may not be receiving social and emotional supports through IEP or 504 Plans, or these supports may use a deficit rather than a strength-based approach. This study used a youth participatory action research method to empower twice-exceptional students to cocreate a strength-based, behavioral intervention plan to help them self-modulate strong emotional responses that hindered their …

Thermodynamic Assessment Of Chromium Corrosion In The Na-K-Mg-U(Iii, Iv) Chloride Salt, Jacob Allen Yingling

Theses and Dissertations

Thermodynamic descriptions of high-order molten chloride salt systems are essential for the development of fast molten salt reactor (MSR) technologies. However, a complete thermodynamic assessment of the essential Na-K-Mg-U(III)-U(IV) molten chloride salt with the most prevalent CrCl2 corrosion product has yet to be provided. This is remedied in the present work through application of the CALculation of PHAse Diagrams (CALPHAD) approach to the available thermodynamic data and new measurements that include differential scanning calorimetry (DSC) observations for previously unexplored two and three component chloride salt systems. Through these efforts, a unique approach was developed for the quantification of uncertainty in …

“Nothing To Do But Be Borne And Steered”: Unpacking Feminist Scripts In Elana Arnold’S Damsel, Jenna Spiering, Nicole Ann Amato

Faculty Publications

Feminism in novels marketed for young adults often reflects the values of a popular feminism that relies on individual and personal means of empowerment, rather than critiquing or seeking to dismantle systems of domination. In this paper, we illumminate frameworks and methods for engaging students in careful readings and evaluations of texts marketed as feminist, through an analysis of Elana Arnold’s feminist fairy tale, Damsel (2018). Drawing on theoretical frameworks of popular feminism, feral feminism, and theories of becoming, the authors use Critical Content Anlaysis to explore several tenets in contemporary feminist thought in order to analyze Arnold’s text and …

Mechanistic Insights Into An Iron-Responsive Repressor, Fep1, From Schizosaccharomyces Pombe, Allison Nicole Kimsey

Theses and Dissertations

Iron is an essential metal cofactor required for a variety of biochemical pathways in most living organisms. In recent years, the nonpathogenic fungi Schizosaccharomyces pombe has been used to study iron regulation and uncover the molecular mechanisms for controlling intracellular iron levels. Some of these regulation pathways are conserved with those of pathogenic fungi, making these studies applicable for the future development of antifungals that target iron homeostasis. In S. pombe, the GATA-type transcriptional repressor Fep1 is responsible for repressing iron uptake genes during times of iron abundance. Previous reports have proposed that the binding of an iron-sulfur (Fe-S) …

Liquid Phase Modeling In Metal Catalysis And In Zeolites, Subrata Kumar Kundu

Theses and Dissertations

Liquid phase processing is often desired for selective product formation, such as during catalytic conversion of biomass, and for purification of waste-water streams. Since the liquid phase environment influences the adsorption properties and reactivity of solid catalysts and porous materials, significant performance changes have been observed as a function of solvent properties for various industrial catalytic and separation processes. There is a need to better understand these solvation effects on processes at solid-liquid interfaces and to develop novel multiscale models that permit one to explore solvation effects on surface catalyzed reactions and during adsorption in porous media such as zeolites. …

The Optimization Of Anion Exchange Membrane Fuel Cells And Water Electrolyzers By Varying Catalyst Design And Changing Gas Inlet Composition, Jasmine D. Bohannon

Theses and Dissertations

Researchers around the globe are looking to avoid the consequences of climate change by shifting away from the burning of fossil fuels as a source of energy. While using fossil fuels have negatively affected the earth’s climate for at least the last hundred and fifty years, the introduction of renewables looks to use abundant and naturally occurring resources. Sources of renewable energy include solar power, wind power, hydropower, geothermal energy, and biomass2 . These sources work by converting the abundant source into mechanical, electrical, or chemical energy that can be used to power industrial plants or residential areas and they …

“Even The Little Things Matter:” A Phenomenological Study On Factors Impacting Student Motivation During And After Covid-Related Disruptions In Education, Jennifer Ferris-Crisafulli

Theses and Dissertations

The COVID-19 pandemic brought about unprecedented disruptions in education, as schools were forced to make a rapid transition to virtual learning in March 2020. Students’ motivation seemed to decline significantly during and after this virtual learning period, which ranged from months to over a year in various areas of the United States. This study seeks to understand the factors impacting student motivation during and after this virtual learning period.

This action research study was conducted using a qualitative, phenomenological approach. Data was collected from open-ended surveys and semi-structured interviews during Spring 2021 and Spring 2022. Data was analyzed through the …

Implementing A Technology-Based Instructional Module In An Introduction To Engineering Course: The Impact On Student’S Vocabulary Retention And Attitudes Towards Learning, Robin T. Amick

Theses and Dissertations

The purpose of this study was to evaluate the academic impact of a technology-based instructional module for content vocabulary instruction in the Project Lead the Way (PLTW) Introduction to Engineering course. The goal of the study was to answer two key questions: 1) How does implementing a technology-based instructional module impact Engineering vocabulary academic gains for students taking the Introduction to Engineering course? and 2) What is the effect of implementing a technology-based instructional model on attitudes towards learning Engineering vocabulary for students taking the Introduction to Engineering course? This study was conducted with Introduction to Engineering students (N …

Human Activity Recognition (Har) Using Wearable Sensors And Machine Learning, Chrisogonas Odero Odhiambo

Theses and Dissertations

Humans engage in a wide range of simple and complex activities. Human Activity Recognition (HAR) is typically a classification problem in computer vision and pattern recognition, to recognize various human activities. Recent technological advancements, the miniaturization of electronic devices, and the deployment of cheaper and faster data networks have propelled environments augmented with contextual and real-time information, such as smart homes and smart cities. These context-aware environments, alongside smart wearable sensors, have opened the door to numerous opportunities for adding value and personalized services to citizens. Vision-based and sensory-based HAR find diverse applications in healthcare, surveillance, sports, event analysis, Human-Computer …

The Salvation Of The Africana Child: Via The Role Of The Black Woman In Educational Leadership, Tamara S. Taylor

Theses and Dissertations

Black Women principals have unique experiences that they have lived that influence the way they lead schools. Strong and committed leadership creates school environments where children can thrive.

This study illuminated the connectivity of race, class, and gender to the lived experiences of Black Women principals according to the Africana Womanism paradigm set forth by Dr. Clenora Hudson-Weems (2020). The question my research sought to answer was: How do the lived experiences, as they relate to race, class, and gender, of Black Women principals impact the way they lead? The sub-question for the study was: How do the lived experiences …

Too Feminine For Execution?: Gender Stereotypes And The Media’S Portrayal Of Women Sentenced To Death, Kelsey M. Collins

Theses and Dissertations

Traditional gender norms prescribing women as more nurturing and less aggressive than men have led to both the reluctance to view women as capable of violence, as well as a greater willingness to execute men than women in the United States. To make sense of the instances where women are sentenced to death, the media often pathologizes and/or demonizes them. Scholars have found that demonizing and dehumanizing those executed is a necessity to the implementation of capital punishment, both in cases of male and female defendants. To better understand how the news media have framed the gender and racial narratives …