Digital Commons Network^™

Estimating Cardiorespiratory Fitness Without Exercise Testing Or Physical Activity Status In Healthy Adults: Regression Model Development And Validation, Robert Sloan, Marco Visentini-Scarzanella, Susumu Sawada, Xuemei Sui M.D., M.P.H., Ph.D.

Faculty Publications

Background: Low cardiorespiratory fitness (CRF) is an independent predictor of morbidity and mortality. Most health care settings use some type of electronic health record (EHR) system. However, many EHRs do not have CRF or physical activity data collected, thereby limiting the types of investigations and analyses that can be done.

Objective: This study aims to develop a nonexercise equation to estimate and classify CRF (in metabolic equivalent tasks) using variables commonly available in EHRs.

Methods: Participants were 42,676 healthy adults (female participants: n=9146, 21.4%) from the Aerobics Center Longitudinal Study examined from 1974 to 2005. The nonexercise estimated CRF was …

Prisoners Of Scale: Downscaling Community Resilience Measurements For Enhanced Use, Sahar Derakshan, Leah Blackwood, Margot Habets, Julia F. Effgen, Susan L. Cutter

Faculty Publications

As improved data availability and disaster resilience knowledge help progress community resilience quantification schemes, spatial refinements of the associated empirical methods become increasingly crucial. Most existing empirically based indicators in the U.S. use county-level data, while qualitatively based schemes are more locally focused. The process of replicating resilience indices at a sub-county level includes a comprehensive study of existing databases, an evaluation of their conceptual relevance in the framework of resilience capitals, and finally, an analysis of the statistical significance and internal consistency of the developed metrics. Using the U.S. Gulf Coast region as a test case, this paper demonstrates …

A Preliminary Study Of Proinflammatory Cytokines And Depression Following West Nile Virus Infection, Allison Lino, Timothy A. Erickson, Melissa Nolan Ph.D., Mph, Kristy O. Murray, Shannon E. Ronca

Faculty Publications

West Nile virus (WNV) is a neurotropic flavivirus that can cause acute febrile illness leading to neuroinvasive disease. Depression is a well-described outcome following infection, but the underlying pathogenic mechanisms are unknown. Proinflammatory cytokines play important roles in WNV infection, but their role in depression post-WNV remains unstudied. This research aimed to retrospectively evaluate associations between proinflammatory cytokines and new onset depression in a WNV cohort. Participants with asymptomatic WNV infection were significantly less likely to report new onset depression when compared to those with symptomatic disease. Participants with encephalitis and obesity were significantly more likely to report new onset …

Perceptions Of Hazing Among Young Male United States Military Service Members: A Qualitative Analysis, Elizabeth C. Metzger, Jasmin N. Bennett, Cristobal S. Berry-Caban, Elizabeth J. Allan, Christopher J. Guenthner, Bryce M. Meerhaeghe, Brian Borsari, Donna M. Kazemi Phd, Rn, Cne, Fiaan, Lindsay M. Orchowski

Faculty Publications

This study examines hazing among a sample of young male service members in the United States (US) military. Individual semi-structured interviews were conducted with active duty service members (N = 10) aged 18 to 24 at a large Southeastern US Army post to examine their conceptualization of hazing. Thematic analysis revealed three emergent themes: (1) the definition of hazing and hazing behaviors; (2) the ritualistic nature of hazing; and (3) the sexual nature of hazing. Most participants provided their own definition of hazing. One participant had difficulty in differentiating between hazing and bullying, the others had distinct definitions as …

Climate Change Reshuffles Northern Species Within Their Niches, Laura H. Antao, Benjamin Weigel, Giovanni Strona, Maria Hallfors, Elina Kaarlejarvi, Tad Dallas, Oystein H. Opedal, Janne Heliola, Heikki Henttonen, Otso Huitu, Erkki Korpimaki, Mikko Kuussaari, Aleksi Lehikoinen, Reima Leinonen, Andreas Lindén, Paivi Merila, Hannu Pietianinen, Juha Poyry, Maija Salemaa, Tiina Tonteri, Kristiina Vuorio, Otso Ovaskainen, Marjo Saastamoinen, Jarno Vanhatalo, Tomas Roslin, Anna-Liisa Laine

Faculty Publications

Climate change is a pervasive threat to biodiversity. While range shifts are a known consequence of climate warming contributing to regional community change, less is known about how species’ positions shift within their climatic niches. Furthermore, whether the relative importance of different climatic variables prompting such shifts varies with changing climate remains unclear. Here we analysed four decades of data for 1,478 species of birds, mammals, butterflies, moths, plants and phytoplankton along a 1,200 km high latitudinal gradient. The relative importance of climatic drivers varied non-uniformly with progressing climate change. While species turnover among decades was limited, the relative position …

The Lived Experience Of Health Insurance: An Analysis And Proposal For Reform, Jacqueline R. Fox

Faculty Publications

People are carrying tens of billions of dollars of medical debt, much of it in collections. We delay going to the Emergency Department while having a heart attack because it may cost too much. Doctors try to help insured patients find the best coupon to offset the high copayment for a necessary prescription drug. For inexpensive drugs, insurers make a profit by clawing back copayments that exceed what the drug costs. People who are already arbitrarily disadvantaged because of race, gender, health status, LGBTQ status, obesity, etc. are disproportionately burdened by all of this.

No one would design a system …

June 1, 2022 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

Note: Awaiting Record of Attendance

Verbal Inhibition Declines Among Older Women With High Fmr1 Premutation Expansions: A Prospective Study, Nell Maltman, Leann Dawalt, Jinkuk Hong, Audra Sterling, Elizabeth Berry-Kravis, Jessica Klusek, Marsha R. Mailick

Faculty Publications

The FMR1 premutation has been associated with difficulties in executive functioning, including verbal inhibition. However, little is known about the longitudinal profiles of verbal inhibition among FMR1 premutation carriers, particularly in women, and how individual factors such as aging and CGG repeat length may contribute to changes in verbal inhibition over time. The present study examined verbal inhibition performance (i.e., inhibition errors) on the Hayling Sentence Completion Task in a cohort of 92 women with the FMR1 premutation across two timepoints approximately three years apart. We examined the effects of age, CGG repeat length, and their interactions on verbal inhibition …

Unrestricted Factor Analysis: A Powerful Alternative To Confirmatory Factor Analysis, Jan-Benedict E.M. Steenkamp, Alberto Maydeu-Olivares

Faculty Publications

The gold standard for modeling multiple indicator measurement data is confirmatory factor analysis (CFA), which has many statistical advantages over traditional exploratory factor analysis (EFA). In most CFA applications, items are assumed to be pure indicators of the construct they intend to measure. However, despite our best efforts, this is often not the case. Cross-loadings incorrectly set to zero can only be expressed through the correlations between the factors, leading to biased factor correlations and to biased structural (regression) parameter estimates. This article introduces a third approach, which has emerged in the psychometric literature, viz., unrestricted factor analysis (UFA). UFA …

Deconstructing Tiktok Videos On Mental Health: Cross-Sectional, Descriptive Content Analysis, Corey H. Basch, Lorie Donelle Phd, Rn, Fcan, Joseph Fera, Christie Jaime

Publications

BACKGROUND: Social media platforms that are based on the creation of visual media, such as TikTok, are increasingly popular with adolescents. Online social media networks provide valuable opportunities to connect with each other to share experiences and strategies for health and wellness. OBJECTIVE: The aim of this study was to describe the content of the hashtag #mentalhealth on TikTok. METHODS: This cross-sectional, descriptive content analysis study included 100 videos with the hashtag #mentalhealth on TikTok. All videos that included the hashtag #mentalhealth were analyzed and coded for the presence of content categories. Additionally, the comments to each video were viewed …

Dyt-Prkra Mutation P222l Enhances Pact's Stimulatory Activity On Type I Interferon Induction, Lauren S. Vaughn, Kenneth Frederick, Samuel B. Burnett, Nutan Sharma, D. Cristopher Bragg, Sarah Camargos, Francisco Cardoso, Rekha C. Patel

Faculty Publications

DYT-PRKRA (dystonia 16 or DYT-PRKRA) is caused by mutations in the PRKRA gene that encodes PACT, the protein activator of interferon (IFN)-induced double-stranded (ds) RNA-activated protein kinase (PKR). PACT participates in several cellular pathways, of which its role as a PKR activator protein during integrated stress response (ISR) is the best characterized. Previously, we have established that the DYT-PRKRA mutations cause enhanced activation of PKR during ISR to sensitize DYT-PRKRA cells to apoptosis. In this study, we evaluate if the most prevalent substitution mutation reported in DYT-PRKRA patients alters PACT’s functional role in induction of type …

Testing Seefeldt's Proficiency Barrier: A Longitudinal Study, Fernando Garbeloto Dos Santos, Matheus Maia Pacheco, David F. Stodden Ph.D., Go Tani, José António Ribeiro Maia

Faculty Publications

The idea that proficiency in the fundamental movement skills (FMS) is necessary for the development of more complex motor skills (i.e., the proficiency barrier) and to promote health-enhancing physical activity and health-related physical fitness levels is widespread in the literature of motor development. Nonetheless, to the best of our knowledge, there is no study assessing whether children presenting proficiency below a specified proficiency barrier would demonstrate difficulty in improving performance in more complex skills—even when subjected to a period of practice in these complex skills. The present study tested this. Eighty-five normal children (44 boys) aged 7 to 10 years …

The Cosmopolitan Evergreen And The Global Digital, Lorraine Janzen Kooistra

Studies in Scottish Literature

Examines how Patrick Geddes’s The Evergreen: A Northern Seasonal used the affordances of fin-de-siècle print culture to imbricate the regional and the transnational, and shows how the magazine’s digital remediation on Yellow Nineties 2.0 makes its cosmopolitan vision newly accessible to global audiences today.

Machine Learning Techniques For Pile-Up Rejection In Cryogenic Calorimeters, G. Fantini, A. Armatol, E. Armengaud, W. Armstrong, Frank Avignone Iii, O. Azzolini, A. Barabash, G. Bari, D. Baudin, F. Bellini, G. Benato, M. Beretta, L. Bergé, M. Biassoni, J. Billard, V. Boldrini, A. Branca, C. Brofferio, C. Bucci, J. Camilleri, Carl Rosenfeld, Carl Rosenfeld, Jeffery R. Wilson, Et. Al.

Faculty Publications

CUORE Upgrade with Particle IDentification (CUPID) is a foreseen ton-scale array of Li₂MoO₄ (LMO) cryogenic calorimeters with double readout of heat and light signals. Its scientific goal is to fully explore the inverted hierarchy of neutrino masses in the search for neutrinoless double beta decay of ¹⁰⁰Mo. Pile-up of standard double beta decay of the candidate isotope is a relevant background. We generate pile-up heat events via injection of Joule heater pulses with a programmable waveform generator in a small array of LMO crystals operated underground in the Laboratori Nazionali del Gran Sasso, Italy. This allows …

Dietary Score Associations With Markers Of Chronic Low-Grade Inflammation: A Cross-Sectional Comparative Analysis Of A Middle- To Older-Aged Population, Seán R. Miller, Pilar Navarro, Janas M. Harrington, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd, Ivan J. Perry, Catherine M. Phillips

Faculty Publications

Purpose

To assess relationships between the Dietary Approaches to Stop Hypertension (DASH), Mediterranean Diet (MD), Dietary Inflammatory Index (DII^®) and Energy-adjusted DII (E-DII™) scores and pro-inflammatory cytokines, adipocytokines, acute-phase response proteins, coagulation factors and white blood cells.

Methods

This was a cross-sectional study of 1862 men and women aged 46–73 years, randomly selected from a large primary care centre in Ireland. DASH, MD, DII and E-DII scores were derived from validated food frequency questionnaires. Correlation and multivariate-adjusted linear regression analyses with correction for multiple testing were performed to examine dietary score relationships with biomarker concentrations.

Results

In fully …

Institutional Betrayals As Sex Discrimination, Emily Suski

Faculty Publications

Title IX jurisprudence has a theoretical and doctrinal inadequacy. Title IX’s purpose is to protect public school students from sex discrimination in all its forms. Yet, courts have only recognized three relatively narrow forms of sex discrimination under it. Title IX jurisprudence, therefore, cannot effectively recognize as sex discrimination the independent injuries, called institutional betrayals, that schools impose on students because they have suffered sexual harassment. Institutional betrayals occur when schools betray students’ trust in or dependency on them by failing to help students in the face of their sexual harassment. These injuries cause harms that can be more severe …

The Majorana Demonstrator Readout Electronics System, N. Abgrall, M. Amman, I. J. Arnquist, Frank Avignone Iii, A. S. Barabash, C. J. Barton, P. J. Barton, F. E. Bertrand, K. H. Bhimani, B. Bos, A. W. Bradley, T. H. Burritt, M. Busch, M. Buuck, T. S. Caldwell, Y-D. Chan, C. D. Christofferson, P.-H. Chu, M. L. Clark, R. J. Cooper, C. Cuesta, Et. Al.

Faculty Publications

The Majorana Demonstrator comprises two arrays of high-purity germanium detectors constructed to search for neutrinoless double-beta decay in 76Ge and other physics beyond the Standard Model. Its readout electronics were designed to have low electronic noise, and radioactive backgrounds were minimized by using low-mass components and low-radioactivity materials near the detectors. This paper provides a description of all components of the Majorana Demonstrator readout electronics, spanning the front-end electronics and internal cabling, back-end electronics, digitizer, and power supplies, along with the grounding scheme. The spectroscopic performance achieved with these readout electronics is also demonstrated.

Learning To Cycle: A Cross-Cultural And Cross-Generational Comparison, Rita Cordovil, Cristiana Mercê, Marco Branco, Frederico Lopes, David Catela, Elina Hasanen, Arto Laukkanen, Patrizia Tortella, Guido Fumagalli, Cristina Sá, Boris Jidovtseff, Linus Zeuwts, An V. De Meester, Farid Bardid, Ricardo Fujikawa, Sanne Veldman, Silvija Zlatar, Isaac Estevan

Faculty Publications

Background: Learning to cycle is an important milestone for children, but the popularity of cycling and the environmental factors that promote the development and practice of this foundational movement skill vary among cultures and across time. This present study aimed to investigate if country of residence and the generation in which a person was born influence the age at which people learn to cycle.

Methods: Data were collected through an online survey between November 2019 and December 2020. For this study, a total of 9,589 responses were obtained for adults (self-report) and children (parental report) living in 10 countries (Portugal, …

Audio-Based Wildfire Detection On Embedded Systems, Hung-Tien Huang, Austin Downey, Jason D. Bakos

Faculty Publications

The occurrence of wildfires often results in significant fatalities. As wildfires are notorious for their high speed of spread, the ability to identify wildfire at its early stage is essential in quickly obtaining control of the fire and in reducing property loss and preventing loss of life. This work presents a machine learning wildfire detecting data pipeline that can be deployed on embedded systems in remote locations. The proposed data pipeline consists of three main steps: audio preprocessing, feature engineering, and classification. Experiments show that the proposed data pipeline is capable of detecting wildfire effectively with high precision and is …

To Stick Or Not To Stick: The Multiple Roles Of Cell Adhesion Molecules In Neural Circuit Assembly, Trevor Moreland, Fabienne E. Poulain

Faculty Publications

Precise wiring of neural circuits is essential for brain connectivity and function. During development, axons respond to diverse cues present in the extracellular matrix or at the surface of other cells to navigate to specific targets, where they establish precise connections with post-synaptic partners. Cell adhesion molecules (CAMs) represent a large group of structurally diverse proteins well known to mediate adhesion for neural circuit assembly. Through their adhesive properties, CAMs act as major regulators of axon navigation, fasciculation, and synapse formation. While the adhesive functions of CAMs have been known for decades, more recent studies have unraveled essential, non-adhesive functions …

Zintl Phase Compounds Mg3Sb2-XBiX (X=0, 1, And 2) Monolayers: Electronic, Phonon And Thermoelectric Properties From Ab Initio Calculations, Zheng Chang, Jing Ma, Kunpeng Yuan, Jiongzhi Zheng, Bin Wei, Mohammed Al-Fahdi, Yufei Gao, Xiaoliang Zhang, Hezhu Shao, Ming Hu, Dawei Tang

Faculty Publications

The Mg₃Sb_2−xBi_x family has emerged as the potential candidates for thermoelectric applications due to their ultra-low lattice thermal conductivity (K_L) at room temperature (RT) and structural complexity. Here, using ab initio calculations of the electron-phonon averaged (EPA) approximation coupled with Boltzmann transport equation (BTE), we have studied electronic, phonon and thermoelectric properties of Mg₃Sb_2−xBi_x (x = 0, 1, and 2) monolayers. In violation of common mass-trend expectations, increasing Bi element content with heavier Zintl phase compounds yields an abnormal change in K_L in two-dimensional Mg₃Sb …

April 26, 2022 General Faculty Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Home-Grown School Feeding: Implementation Lessons From A Pilot In A Poor Ethnic Minority Community In Vietnam, Sabina Di Prima, Dai Nguyen Dinh, Demi D. Reurings, E Pamela Wright Phd, Ms, Med, Rn, Cen, Dirk Essink, Jacqueline E. Broerse

Publications

BACKGROUND:

Undernutrition threatens the health and future of preschool children in disadvantaged remote communities. Home-grown school feeding (HGSF) in nursery schools could positively impact children's nutrition while creating multiple benefits for the whole community. However, evidence is lacking on implementation of HGSF within multi-sectoral programs in remote areas.

OBJECTIVE:

This study assessed an HGSF pilot intervention, part of a nutrition-sensitive agriculture (NSA) program, in a mountain ethnic minority community in Vietnam. It aimed to identify the changes brought about by the intervention, in particular diversity of children's food, food sources, barriers and facilitators to change, and future challenges and strategies. …

Attention/Deficit Hyperactivity Disorder In Adolescent And Young Adult Males With Fragile X Syndrome, Jessica Klusek, Shannon L. O'Connor, Alexandra Hickey, Kimberly J. Hills, Leonard Abbeduto, Jane E. Roberts

Faculty Publications

This study characterized the rates of rates of attention-deficit/hyperactivity disorder (ADHD) in adolescent and young adult males with fragile X syndrome (FXS) using a multi-method approach integrating a DSM-based parent interview (Children’s Interview for Psychiatric Syndromes; P-ChIPS, Fristad et al., 1998) and a parent rating scale (Child Behavior Checklist; CBCL, Achenbach, 2001). Thirty-one males with FXS, aged 16-24 years, participated. Forty-two percent met DSM-5 criteria for ADHD and 35% exceeded the CBCL cut-offs. Agreement between the two classification methods was fair (κ=0.38). Autism symptom severity and nonverbal cognitive ability did not predict ADHD diagnoses/symptoms. Results show …

Key Stakeholder Perspectives On Challenges And Opportunities For Rural Hpv Vaccination In North And South Carolina, Laura J. Fish, Sayward Harrison, Jodi-Ann Mcdonald, Valerie Yelverton, Charnetta Williams, Emmanuel B. Walter, Lavanya Vasudevan

Faculty Publications

The objective of this study was to identify factors at the individual, provider, and systems levels that serve as challenges or opportunities for increasing adolescent vaccination—including Human Papillomavirus (HPV) vaccination—in rural communities in the southern United States (US). As part of a broader study to increase HPV vaccine uptake in the southern US, we conducted in-depth interviews with vaccination stakeholders representing public health and education agencies in North Carolina (NC) and South Carolina (SC). Fourteen key stakeholders were recruited using purposive sampling to obtain insights into challenges and solutions to rural-urban disparities in HPV vaccination coverage. Stakeholders were also queried …

Key Stakeholder Perspectives On Challenges And Opportunities For Rural Hpv Vaccination In North And South Carolina, Laura J. Fish, Sayward Harrison, Jodi-Ann Mcdonald, Valerie Yelverton, Charnetta Williams, Emmanuel B. Walter, Lavanya Vasudevan

Faculty Publications

The objective of this study was to identify factors at the individual, provider, and systems levels that serve as challenges or opportunities for increasing adolescent vaccination—including Human Papillomavirus (HPV) vaccination—in rural communities in the southern United States (US). As part of a broader study to increase HPV vaccine uptake in the southern US, we conducted in-depth interviews with vaccination stakeholders representing public health and education agencies in North Carolina (NC) and South Carolina (SC). Fourteen key stakeholders were recruited using purposive sampling to obtain insights into challenges and solutions to rural-urban disparities in HPV vaccination coverage. Stakeholders were also queried …

The Daily Gamecock, Remember When, April 2022, University Of South Carolina, Office Of Student Media

April

No abstract provided.

Do We Trust The Government? Attributes Of Covid-19 Vaccine Hesitancy And Acceptance In Nigeria, Osmond C. Ekwebelem, Helen Onyeaka, Ismaeel Yunusa Ph. D., Taghi Miri, Yahwedalu M. Onwuneme, Ayeni T. Eunice, Amara Anyogu, Bright Obi, Ngwogu Ada Carol

Faculty Publications

Objectives:

A significant percentage of the population must be vaccinated to achieve herd immunity. Therefore the success of a vaccination program relies on the level of acceptance. This present study seeks to understand COVID-19 vaccine acceptance and hesitancy in Nigeria by assessing the public's willingness to get vaccinated.

Study design:

This is a population-based cross-sectional study. Data were derived through a structured online survey.

Methods:

A cross-sectional study was conducted among adult residents in Nigeria in March 2021 using a structured online questionnaire. The questionnaire surveyed participants' demographic characteristics and perception of COVID-19 and the COVID-19 vaccine. Descriptive statistics and …

Chimney Identification Tool For Automated Detection Of Hydrothermal Chimneys From High-Resolution Bathymetry Using Machine Learning, Isaac Keohane, Scott White

Faculty Publications

Identifying the locations of hydrothermal chimneys across mapped areas of seafloor spreading ridges unlocks the ability to research questions about their correlations to geology, the cooling of the lithosphere, and deep-sea biogeography. We developed a Chimney Identification Tool (CIT) that utilizes a Convolutional Neural Network (CNN) to classify 1 m gridded AUV bathymetry and identify the locations of hydrothermal vent chimneys. A CNN is a type of Machine-Learning model that is able to classify raster data based on the shapes and textures in the input, making it ideal for this task. The criteria that have been used in previous manual …

Canonical Sentence Processing And The Inferior Frontal Cortex: Is There A Connection?, Nicholas Riccardi, Chris Rorden, Julius Fridriksson, Rutvik H. Desai

Faculty Publications

The role of left inferior frontal cortex (LIFC) in canonical sentence comprehension is controversial. Many studies have found involvement of LIFC in sentence production or complex sentence comprehension, but negative or mixed results are often found in comprehension of simple or canonical sentences. We used voxel-, region-, and connectivity-based lesion symptom mapping (VLSM, RLSM, CLSM) in left-hemisphere chronic stroke survivors to investigate canonical sentence comprehension while controlling for lexical-semantic, executive, and phonological processes. We investigated how damage and disrupted white matter connectivity of LIFC and two other language-related regions, the left anterior temporal lobe (LATL) and posterior temporal-inferior parietal area …