Digital Commons Network^™

Neighborhood Change On The Mississippi Coast After Hurricane Katrina (2006 – 2019), Margot Habets

Theses and Dissertations

Hurricane Katrina was a historic event, forever changing many lives as well as altering impacted communities in the short and long term. In the fifteen years since the storm, patterns of damage, recovery programs and dollars, and existing neighborhood change have altered demographics in coastal Mississippi. This thesis investigates how population, median age, race, and education demographics have changed at the census tract level in the fourteen years since Hurricane Katrina (2006-2019) compared to pre-Katrina trends (1990-2000). A moving average using American Community Survey data as well as interval changes measure how different neighborhoods have been altered since the storm. …

Sports Nutrition- And Strength And Conditioning-Based Interventions To Bolster Health And Human Performance In Male And Female Tactical Personnel, Harry Paul Cintineo

Theses and Dissertations

Military and law enforcement personnel are required to possess sufficient physical and cognitive fitness to perform their official duties. Tactical athletes must have fast reaction times (RT), high levels of various aspects of muscular performance, including power, strength, and endurance, as well as high anaerobic and aerobic capacities. The purpose of this dissertation was to investigate acute sports nutrition and chronic strength and conditioning strategies to improve health and human performance in tactical athletes, including law enforcement officers, active-duty military service members, and Reserve Officers’ Training Corps (ROTC) cadets and midshipmen.

The first study tested the effects of a combination …

Pyridyl Bis-Urea Macrocycles As Supramolecular Synthons And The Design And Synthesis Of Small Molecule Pharmaceuticals Targeting Ly6k, Devan D. Buchanan

Theses and Dissertations

Assembled pyridyl bis-urea macrocycles have been utilized as 1D supramolecular synthons to construct hierarchical assemblies. These macrocycles have both urea and pyridyl functional groups and can form non-covalent interactions with hydrogen or halogen bond donors through symmetric, ditopic acceptor motifs. Bis-urea macrocycles offer interesting capabilities as synthons to organize donors into well-defined crystal structures. In part, this is due to the urea motifs’ propensity to assemble through hydrogen bonding. New, asymmetric pyridyl macrocycles were synthesized, crystallized, and experimentally probed to determine how symmetry affects their assembly and utility as supramolecular synthons.

The Uphadhyay group identified small molecules, including NSC11150, …

Evaluation Of Monthly And Seasonal Grazing Rates Of Ilyanassa Obsoleta On Benthic Microalgae In The North Inlet Estuary, Brittany Dearmitt

Theses and Dissertations

The eastern mud snail, Ilyanassa obsoleta, is found at densities of 100’s of individuals m^-2 on soft sediments in the intertidal zones of estuaries. These obligate deposit feeders consume microalgae, detritus, larvae, meiofauna, and macrofauna in the surface layers of sediments with possible trophic impacts on benthic microalgal (BMA) biomass. The goals of this study were to quantify mud snail grazing on BMA biomass, observe the variation in monthly and seasonal grazing rates, and evaluate the relationship between atmospheric temperatures and grazing rates. The sites for this experiment were two mudflats in Oyster Landing, North Inlet estuary, South …

Measuring Orthographic Influences On Phonological Processing In Beginning Readers: An Eyetracking Study, Emily Grace Fisher

Theses and Dissertations

Purpose – Both orthographic and phonemic awareness are essential to reading. However, the role of orthographic knowledge in phonemic awareness has not been thoroughly investigated in beginning readers until recently. The purpose of this study was to examine if orthographic knowledge influenced phonological processing in beginning readers and to establish a proof of concept for the use of eyetracking measures to examine these skills in young children.

Method – 22 participants, aged 6-7 years, completed norm-referenced assessments of language and reading ability as well as experimental measures of orthographic and phonological awareness while their eye movements were monitored.

Results – …

A Novel Cognitive Stress Paradigm To Assess Subtle Cognitive Differences In Women With The Fmr1 Premutation, Jillian Margaret Gierman

Theses and Dissertations

Fragile X premutation (FXPM) is a genetic mutation of the FMR1 gene characterized by having between 55-200 CGG repetitions. FXPM women are at risk for a variety of reproductive, cognitive, and neuropsychiatric deficits, including fragile X-associated primary ovarian insufficiency (FXPOI) and fragile X-associated tremor/ataxia syndrome (FXTAS). FXTAS is a late-onset neurodegenerative disorder characterized by tremor, gait ataxia, cognitive decline, brain atrophy, and deficits in executive functions. With the evidence supporting premature aging, prevalence of cognitive deficits, and risk of developing FXTAS and dementia, it is imperative to find a reliable measure that identifies at-risk FXPM women and their subtle cognitive …

Unintended Consequences Of The Electronic Health Record And Cognitive Load In Emergency Department Nurses, Carolyn S. Harmon

Theses and Dissertations

Background: The electronic health record (EHR) was rapidly implemented to improve patient safety. However, this rapid and widespread EHR implementation negatively connects to patient safety. Clinician cognitive overload is also thought to be negatively connected to patient safety, especially in the chaotic emergency department (ED) setting. Limited research has been conducted on unintended consequences of the EHR (UC-EHR) and cognitive load (CL) in ED nurses. Understanding the UC-EHR and CL in ED nurses facilitate informed interventions to improve nursing practice and patient safety.

Aims: Guided by the Systems Engineering Initiative for Patient Safety (SEIPS) 2.0 framework, the aims of this …

Healthy Aging Beyond Sex And Gender Binaries, Nicole M. Lampe

Theses and Dissertations

An estimated 2.7 million sexual and gender minority (SGM) adults 50+ reside in the United States (US) with this number projected to increase to more than 5 million by 2060 (Flatt et al. 2022; Fredriksen-Goldsen and Kim 2017). Medical research, education, and practice in the United States (US) often erase sex and gender variation, thus ignoring the experiences of older adults living beyond Western sex and gender binary systems (e.g., female/male and women/men), particularly transgender, non-binary, and/or intersex (TNBI) populations. Such erasure stems from TNBI older adult structural incompetency or the failure to understand how macro-level systems, institutions, and structures …

Identifying Novel Pharmacogenetic Markers For Cancer Treatments: Exploiting Cancers Deficient In The Nucleotide Pool Sanitizing Hydrolases Nudt15 And Nudt18, Jacob Chandler Massey

Theses and Dissertations

The NUDIX hydrolases are a super family of enzymes with purported enzymatic activities of nucleotide hydrolases. The activity of the founding member, NUDT1 (also known as MTH1) is established to be a nucleotide hydrolase for d-8-oxoGTP, which is a mutagenic precursor if incorporated into DNA. Therefore, its activity serves to sanitize the nucleotide pool of mutagenic precursors. While known to be highly conserved among all organisms, the enzymatic and biological functions for nearly all the family members remain largely unexplored and unknown. Substrates of family members have been found to include canonical (deoxy)nucleotide triphosphates, oxidized (deoxy)nucleotide triphosphates, and non-nucleoside polyphosphates. …

La Materialidad De Las Vivencias Femeninas: Cuerpos Discapacitados, Prostituidos Y Violados En Las Narrativas Mexicanas Escritas Por Las Mujeres, Hyanghee Lee

Theses and Dissertations

Esta disertación explora los temas específicamente vinculados a las vivencias de las mujeres mexicanas tales como la anormalidad, la discapacidad, la locura, la prostitución, la violencia de género y la madre mutilada que no pueden abordarse sin tener en cuenta el cuerpo femenino. En este proyecto se discuten estas temáticas aplicando el concepto de la corporeidad o la materialidad de las vivencias que experimentan las mujeres en dicho espacio geopolítico manifestadas en cuatro narrativas mexicanas producidas por las mujeres-escritoras en la época contemporánea del final del siglo XX y al comienzo del siglo XXI: Nadie me verá llorar (1999) de …

Mechanisms Of Connectivity In Neuronal Development, Janay Vacharasin

Theses and Dissertations

The development of neuronal connectivity requires the careful orchestration of multiple cellular processes including the control of neuronal arborization and synapse formation or function. Defects in these processes during neuronal development will give rise to disorders of neuronal connectivity like autism. In the present work, we examine the genetic and epigenetic mechanisms that build the neuronal wiring of the developing brain. We use human stem cell-derived neurons to study neuronal arborization and function focusing on genetic and environmental risk factors of neurodevelopmental disorders that include autism and intellectual disability. Specifically, we focused on the contribution of the endomembrane, chromatin, and …

Investigating Performance Of Model Fit Indices In Multiple-Group Confirmatory Factor Analysis: Complications With Ordinal Data, Ning Jiang

Theses and Dissertations

The purpose of this study is to evaluate the performance of three commonly used model fit indices when measurement invariance is tested in the context of multiple-group CFA with categorical-ordered data. As applied researchers are increasingly aware of the importance of testing measurement invariance, as well as Likert-type scales are frequently used in the social and behavioral sciences, specific guidelines are in need for establishing measurement invariance using model fit indices.

To achieve the study goal, two Monte Carlo simulation studies were conducted. Study 1 investigated the sampling variability of fit indices under different levels of invariance tests. Based on …

Transcranial Alternating Current Stimulation As An Adjuvant For Nonfluent Aphasia Therapy: A Proof-Of-Concept Study, Lynsey Mcgrath Keator

Theses and Dissertations

Identifying effective and efficient rehabilitation tools is crucial to improve language outcomes for persons living with chronic aphasia. Speech entrainment has proved to be particularly successful in improving speech output in nonfluent aphasia. It is hypothesized that, for patients with aberrant oscillatory synchronization between anterior and posterior language regions of the left hemisphere, speech entrainment may act as an external gaiting mechanism to bolster an impaired efference copy and improve synchrony between these regions. Theoretical and empirical evidence supports this idea that speech production relies on anterior-posterior connectivity in the left hemisphere.

Transcranial alternating current stimulation (tACS) delivers low, periodically-alternating …

Automated Contingency Management For Water Recycling System, Shijie Tang

Theses and Dissertations

NASA’s exploration program envisions the utilization of a Deep Space Habitat (DSH) for human exploration of the space environment in the vicinity of Mars and beyond. Communication latency and extreme limitations of power and life-supporting resources make it imperative to operate the DSH systems in a highly autonomous fashion. One such system is the Environmental Control and Life Support System (ECLSS) which needs to be monitored and optimized to support its designated missions.

Integrated System Health Management (ISHM) technologies have been developed in the past decades to provide a real-time assessment of system health and use this information to improve …

“Where The Truth Really Lies”: Listening To Voices From African American Communities In The Southern States About Covid-19 Vaccine Information And Communication, Ran Zhang, Shan Qiao, Brooke Mckeever, Bankole Olatosi, Xiaoming Li

Faculty Publications

The high uptake of COVID-19 vaccines is one of the most promising measures to control the pandemic. However, some African American (AA) communities exhibit vaccination hesitancy due to mis- or disinformation. It is important to understand the challenges in accessing reliable COVID-19 vaccine information and to develop feasible health communication interventions based on voices from AA communities. We conducted 2 focus group discussions (FGDs) among 18 community stakeholders recruited from 3 counties in South Carolina on 8 October and 29 October 2021. The FGDs were conducted online via Zoom meetings. The FGD data were managed and thematically analyzed using NVivo …

Listening To Voices From African American Communities In The Southern States About Covid-19 Vaccine Information And Communication: A Qualitative Study, Ran Zhang, Shan Qiao, Bankole Olatosi Ph.D., Xiaoming Li Ph.D.

Faculty Publications

The high uptake of COVID-19 vaccines is one of the most promising measures to control the pandemic. However, some African American (AA) communities exhibit vaccination hesitancy due to mis- or disinformation. It is important to understand the challenges in accessing reliable COVID-19 vaccine information and to develop feasible health communication interventions based on voices from AA communities. We conducted 2 focus group discussions (FGDs) among 18 community stakeholders recruited from 3 counties in South Carolina on 8 October and 29 October 2021. The FGDs were conducted online via Zoom meetings. The FGD data were managed and thematically analyzed using NVivo …

Eeg Evidence Of Altered Functional Connectivity And Microstate In Children Orphaned By Hiv/Aids, Huang Gu, Xueke Shan, Hui He, Junfeng Zhao, Xiaoming Li Ph.D.

Faculty Publications

Children orphaned by HIV/AIDS (“AIDS orphans”) suffer numerous early-life adverse events which have a long-lasting effect on brain function. Although previous studies found altered electroencephalography (EEG) oscillation during resting state in children orphaned by HIV/AIDS, data are limited regarding the alterations in connectivity and microstate. The current study aimed to investigate the functional connectivity (FC) and microstate in children orphaned by HIV/AIDS with resting-state EEG data. Data were recorded from 63 children orphaned by HIV/AIDS and 65 non-orphan controls during a close-eyes resting state. The differences in phase-locking value (PLV) of global average FC and temporal dynamics of microstate were …

Inhibitory Control Of Emotional Interference In Deaf Children: Evidence From Event-Related Potentials And Event-Related Spectral Perturbation Analysis, Qiong Chen, Junfeng Zhao, Huang Gu, Xiaoming Li Ph.D.

Faculty Publications

Background: Impairment of interference control ability may reflect a more general deficit in executive functioning, and lead to an increase in internal-externalized problems such as impulsivity, which has been reported in deaf children. However, few researches have examined the neural mechanism of this impairment.

Methods: This study applied the electroencephalogram (EEG) technique to investigate the interference control ability in 31 deaf children and 28 hearing controls with emotional face-word stroop task.

Results: Results from behavioral task showed that deaf children exhibited lower accuracy compared to hearing controls. As for EEG analysis, reduced activation of ERP components in N1 and enhanced …

My Authentic Self: Rousseau And The Ethics Of Authenticity In The Age Of Gender Ideology, Steven Kessler

Journal of Ideology

This article examines the origins of the contemporary iteration of gender ideology pervasive in the western world today. To accomplish this, the article is broken into three main components. The first component examines the source of where the current trend in picking pronouns, genders, and sexual orientations emanates from. This is attributed to an ideology called, “the ethics of authenticity.” The tenets of the ethics of authenticity are delineated in the article. Another component of the article attributes the origin of authenticity to the work and thought of Jean Rousseau. Specifically, four of his works are examined as fundamentally important …

Adolescent Health Risk Behaviors, Adverse Experiences, And Self-Reported Hunger: Analysis Of 10 States From The 2019 Youth Risk Behavior Surveys, Kathryn L. Krupsky, Sarah Silwa, Hilary Seligman, Andrea D. Brown, Angela D. Liese Ph.D., Zewditu Demissie, Ellen Barnidge

Faculty Publications

We examined associations between adolescent self-reported hunger, health risk behaviors, and adverse experiences during the 2018–2019 school year. Youth Risk Behavior Survey data were pooled from 10 states. Prevalence ratios were calculated, and we assessed effect measure modification by sex. The prevalence of self-reported hunger was 13%. Self-reported hunger was associated with a higher prevalence of every health risk behavior/adverse experience analyzed, even after adjusting for sex, grade, and race/ethnicity. Sex did not modify associations. Findings underscore needs for longitudinal research with more robust measures of adolescent food insecurity to clarify the temporality of relationships.

Search For Multimessenger Signals In Nova Coincident With Ligo/Virgo Detections, M. A. Acero, P. Adamson, L. Aliaga, T. Alion, V. Alakhberdian, N. Anfimov, A. Antoshkin, L. Asquith, A. Aurisano, A. Back, C. Backhouse, M. Biard, N. Balashov, P. Baldi, B. A. Bambah, S. Bashar, K. Bays, S. Bending, R. Bernstein, V. Bhatnagar, Roberto Petti, Et. Al.

Faculty Publications

Using the NOvA neutrino detectors, a broad search has been performed for any signal coincident with 28 gravitational wave events detected by the LIGO/Virgo Collaboration between September 2015 and July 2019. For all of these events, NOvA is sensitive to possible arrival of neutrinos and cosmic rays of GeV and higher energies. For five (seven) events in the NOvA Far (Near) Detector, timely public alerts from the LIGO/Virgo Collaboration allowed recording of MeV-scale events. No signal candidates were found.

Event-Related Brain Potential Correlates Of Event-Based Prospective Memory In Children With Learning Disability, Lili Jing, Qi Zhao, Yafei Zhang, Jiaojiao Wan, Xiaoming Li Ph.D.

Faculty Publications

Prospective memory (PM) has been reported to be impaired in children with learning disabilities (LD), but few studies have examined the underlying neural mechanism of this impairment. To address this issue, the present study applied ERP technique to explore the difference of event-based prospective memory (EBPM) in 21 children with LD and 20 non-LD children with double task paradigm. Results from behavioral data showed that LD children exhibited lower accuracy than non-LD children. The ERP results showed that the two groups displayed significant difference in the ERP components, with longer N300 latency in LD group, but there was no obvious …

The NTh-Order Comprehensive Adjoint Sensitivity Analysis Methodology For Nonlinear Systems (Nth-Casam-N): Mathematical Framework, Dan Gabriel Cacuci

Faculty Publications

This work presents the n^th-Order Comprehensive Adjoint Sensitivity Analysis Methodology for Nonlinear Systems (n^th-CASAM-N), which enables the most efficient computation of exactly determined expressions of arbitrarily high-order sensitivities of generic nonlinear system responses with respect to model parameters, uncertain boundaries, and internal interfaces in the model’s phase space. The mathematical framework underlying the n^th-CASAM-N is proven to be correct by using mathematical induction. The n^th-CASAM-N is formulated in linearly increasing higher-dimensional Hilbert spaces—as opposed to exponentially increasing parameter-dimensional spaces—thus overcoming the curse of dimensionality in sensitivity analysis of nonlinear systems.

Comparative Analysis Of Reactive Power Compensation Devices In A Real Electric Substation, Hannan Tariq, Stanislav Czapp, Sarmad Tariq, Khalid Mehmood Cheema, Aqarib Hussain, Ahmad H. Milyani, Sultan Alghamdi, Z. M. Salem Elbarbary

Faculty Publications

A constant worldwide growing load stress over a power system compelled the practice of a reactive power injection to ensure an efficient power network. For this purpose, multiple technologies exist in the knowledge market out of which this paper emphasizes the usage of the flexible alternating current transmission system (FACTS) and presents a comparative study of the static var compensator (SVC) with the static synchronous compensator (STATCOM), inducted in a real electric substation. The aim is to improve the power factor (PF) and power quality and to encounter reliably extreme conditions. A 220 kV electric substation was opted for the …

Mental/Behavioural Health And Educational Outcomes Of Grandchildren Raised By Custodial Grandparents: A Mixed Methods Systematic Review, Yanfeng Xu Ph.D., Yao Wang, Lauren P. Mccarthy, Theresa Harrison, Hanna Doherty

Faculty and Staff Publications

Grandparents caring for grandchildren has increased globally in the past two decades, but we have a limited understanding of its effects on custodial grandchildren's mental/behavioural health and educational outcomes. This mixed methods systematic review aims to synthesise mental/behavioural health and educational outcomes of custodial grandchildren within custodial grandparent-headed families and with comparison to other types of household structure and further examine factors associated with these outcomes. A systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was conducted. We searched ERIC, Family Studies Abstracts, PsycINFO, PubMed, Scopus, Social Work Abstract and SocINDEX in March 2021 and …

Luminescence And Scintillation In The Niobium Doped Oxyfluoride Rb4Ge5O9F6:Nb, Darren Carone, Vladislav V. Klepov, Scott T. Misture, Joseph C. Schaeperkoetter, Luiz G. Jacobsohn, Mina Aziziha, Juliano Schorne-Pinto, Stuart A. J. Thomson, Adrian T. Hines, Theodore M. Besmann, Hans Conrad Zur Loye

Faculty Publications

A new niobium-doped inorganic scintillating oxyfluoride, Rb₄Ge₅O₉F₆:Nb, was synthesized in single crystal form by high-temperature flux growth. The host structure, Rb₄Ge₅O₉F₆, crystallizes in the orthorhombic space group Pbcn with lattice parameters a = 6.98430(10) Å, b = 11.7265(2) Å, and c = 19.2732(3) Å, consisting of germanium oxyfluoride layers made up of Ge₃O₉ units connected by GeO₃F₃ octahedra. In its pure form, Rb₄Ge₅O₉F₆ shows neither luminescence nor scintillation but when doped …

Episodes Of Liberalization In Autocracies: A New Approach To Quantitatively Studying Democratization, Matthew Wilson, Juraj Medzihorsky, Seraphine F. Maerz, Patrik Lidenfors, Amanda B. Edgell, Vanessa A. Boese, Staffan I. Lindberg

Faculty Publications

This paper introduces a new approach to the quantitative study of democratization. Building on the comparative case-study and large-N literature, it outlines an episode approach that identifies the discrete beginning of a period of political liberalization, traces its progression, and classifies episodes as successful versus different types of failing outcomes, thus avoiding potentially fallacious assumptions of unit homogeneity. We provide a description and analysis of all 383 liberalization episodes from 1900 to 2019, offering new insights on democratic “waves”. We also demonstrate the value of this approach by showing that while several established covariates are valuable for predicting the ultimate …

A Westerly Wind Dominated Puna Plateau During Deposition Of Upper Pleistocene Loessic Sediments In The Subtropical Andes, South America, Alex Pullen, David L. Barbeau Jr, Andrew Leier, Madison Ward, Austin Bruner, Mary Kate Fidler

Faculty Publications

The Tafí del Valle depression (~27° S) in the eastern Andes of Argentina provides a record of late Pleistocene dust deposition in the subtropics of South America. We present large-n U-Pb geochronology data for detrital zircons from upper Pleistocene loess-paleosol deposits. When compared to regional data, the age spectra from the Tafí del Valle samples are most like the southern Puna Plateau, supporting derivation largely from the west and northwest. This runs counter to hypotheses suggesting these loessic sediments were derived from the low elevation plains to the east or extra-Andean Patagonia. Mapping of linear wind erosion features on …

Environmental And Biological Controls On Sedimentary Bottom Types In The Puquios Of The Salar De Llamara, Northern Chile, Erica P. Suosaari, Amanda M. Oehlert, Ioan Lascu, Alan W. Decho, Alan M. Piggot, Alvaro T. Palma, Paul F. Machabee, R. Pamela Reid

Faculty Publications

The Puquios of the Salar de Llamara in the Atacama Desert, northern Chile, is a system of small lakes that is characterized by evaporitic mineral deposition and that commonly hosts microbial communities. This region is known for its extreme aridity, solar irradiance, and temperature fluctuations. The Puquios are a highly diverse ecosystem with a variety of sedimentary bottom types. Our previous results identified electrical conductivity (EC) as a first-order environmental control on bottom types. In the present paper, we extend our analysis to examine the effects of additional environmental parameters on bottom types and to consider reasons for the importance …

Reimagining Info 101: A Tale Of Revisions And New Beginnings, April P. Akins, Casey L. Anthony, Jean Thrift

South Carolina Libraries

Realized that video you love showing in class is nearly as old as your students now? We’ve been there. Lander University librarians spent this summer collaborating to redesign INFO 101, our 1-credit information literacy course. The goals were to keep the course fresh, useful, effective, and synchronized across instructors and delivery methods. This initiative included reformatting into an eight-week schedule offered twice per semester, moving to a new textbook, establishing a shared Blackboard sandbox in the university’s recommended online course template, and ditching the final project. Results will be discussed from the Fall 2021 sections taught face-to-face and online.