Digital Commons Network^™

Identifying The Relationship Between Benzene Exposure And The Development Of Acute Myeloid Leukemia, Jacqueline G. Tally

Senior Honors Projects

My interest in epigenetic carcinogenesis-related research stems from both academic and personal experiences. I have come to recognize the significance of environmental chemical exposures in the development of cancer through my studies in nursing, and nutrition and food science. I am particularly interested in the epigenetics of acute myeloid leukemia (AML) because I am an AML survivor.

AML is a rare and highly malignant cancer. It is estimated 13,780 new cases of AML will be identified in theUnited Statesthis year with a 74% mortality rate (calculated 10,200 deaths/13,780 new cases). AML develops from alterations in the survival and proliferation of …

The Good 5 Cent Cigar (4/27/2012), University Of Rhode Island

The Good 5 Cent Cigar (Student Newspaper Archives)

This is a digitized, downloadable version of the University of Rhode Island school newspaper.

Gender Identity Disorder: An Unethical Diagnosis Of Normal Human Diversity, Julia Churchill Schoellkopf, Jasmine Mena

Lesbian Gay Bisexual Transgender Queer Center

Gender Identity Disorder (GID) is very unique among the other disorders in the Diagnostic and Statistical Manual of Mental Disorders (DSM) because the treatment is used to confirm the alleged disordered belief (Ross 2009). All other disorders in the DSM-IV-TR are defined as the treatment altering the disordered belief and removing the symptoms, not reinforcing them as GID does (Ross 2009). This contradictory nature of the diagnosis has received lots of criticism from professionals over the years and many have offered alternatives.

Curricular Affairs Committee Minutes April 23, 2012, University Of Rhode Island Faculty Senate

Faculty Senate Committee Reports and Appendices

No abstract provided.

Energetic Plasticity Underlies A Variable Response To Ocean Acidification In The Pteropod, Limacina Helicina Antarctica, Brad A. Seibel, Amy E. Maas, Heidi M. Dierssen

Biological Sciences Faculty Publications

Ocean acidification, caused by elevated seawater carbon dioxide levels, may have a deleterious impact on energetic processes in animals. Here we show that high PCO₂ can suppress metabolism, measured as oxygen consumption, in the pteropod, L. helicina forma antarctica, by ~20%. The rates measured at 180–380 µatm (MO₂ = 1.25 M^−0.25, p = 0.007) were significantly higher (ANCOVA, p = 0.004) than those measured at elevated target CO₂ levels in 2007 (789–1000 µatm, = 0.78 M^−0.32, p = 0.0008; Fig. 1). However, we further demonstrate metabolic plasticity in response to regional …

The Good 5 Cent Cigar (4/13/2012), University Of Rhode Island

The Good 5 Cent Cigar (Student Newspaper Archives)

This is a digitized, downloadable version of the University of Rhode Island school newspaper.

The Good 5 Cent Cigar (4/12/2012), University Of Rhode Island

The Good 5 Cent Cigar (Student Newspaper Archives)

This is a digitized, downloadable version of the University of Rhode Island school newspaper.

The Transcriptome And Proteome Of The Diatom Thalassiosira Pseudonana Reveal A Diverse Phosphorus Stress Response, Sonya T. Dyhrman, Bethany D. Jenkins, Tatiana A. Rynearson, Mak A. Saito, Melissa Mercier, Harriet Alexander, Leann P. Whitney, Andrea Drzewianowski, Vladimir V. Bulygin, Erin M. Bertrand, Zhijin Wu, Claudia Benitez-Nelson, Abigail Heithoff

Cell and Molecular Biology Faculty Publications

Phosphorus (P) is a critical driver of phytoplankton growth and ecosystem function in the ocean. Diatoms are an abundant class of marine phytoplankton that are responsible for significant amounts of primary production. With the control they exert on the oceanic carbon cycle, there have been a number of studies focused on how diatoms respond to limiting macro and micronutrients such as iron and nitrogen. However, diatom physiological responses to P deficiency are poorly understood. Here, we couple deep sequencing of transcript tags and quantitative proteomics to analyze the diatom Thalassiosira pseudonana grown under P-replete and P-deficient conditions. A total of …

Curricular Affairs Committee Minutes March 26, 2012, University Of Rhode Island Faculty Senate

Faculty Senate Committee Reports and Appendices

No abstract provided.

Library Impact Statement For Nrs/Bio 417 Herpetology, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for NRU/BIO 417 Herpetology new course proposal. No new library resources are needed to support this course. Responding library faculty member: Michael A. Cerbo II. Requesting faculty member: Nancy E. Karraker.

Library Impact Statement For Nrs/Bio 517 Herpetology, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for NRS/BIO 517 Herpetology. No new library resources are needed to support this course. Responding library faculty member: Micael A. Cerbo II. Requesting faculty member: Nancy E. Karraker.

Coastal Exploration Of The Southern Black Sea Off Ereğli And Sinop, Turkey, Michael L. Brennan, Dan Davis, Chris Roman, Ilya V. Buynevich, Alexis Catsambis, Meko Kofahl, Maureen Merrigan, Suna Tuzun, Muhammet Duman, Derya Urkmez, J. Ian Vaughn, Tufan Turanli

Graduate School of Oceanography Faculty Publications

No abstract provided.

The Good 5 Cent Cigar (2/29/2012), University Of Rhode Island

The Good 5 Cent Cigar (Student Newspaper Archives)

This is a digitized, downloadable version of the University of Rhode Island school newspaper.

Curricular Affairs Committee Minutes February 27, 2012, University Of Rhode Island Faculty Senate

Faculty Senate Committee Reports and Appendices

No abstract provided.

Library Impact Statement For Bio 501 Advanced Scientific Ethics, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for BIO 501 Advanced Scientific Ethics new course proposal. No new resources are required to support this course. Responding library faculty member: Michael A. Cerbo II. Requesting faculty member: Chris Lane.

The Good 5 Cent Cigar (2/15/2012), University Of Rhode Island

The Good 5 Cent Cigar (Student Newspaper Archives)

This is a digitized, downloadable version of the University of Rhode Island school newspaper.

Library Impact Statement For Bio 502 Advanced Scientific Communication, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for BIO 502 Advanced Scientific Communication new course proposal. No new resources are needed to support this course. Responding library faculty member: Michael A. Cerbo II. Requesting faculty member: Chris Lane.

The Metabolic Response Of Pteropods To Acidification Reflects Natural Co2-Exposure In Oxygen Minimum Zones, A. E. Maas, K. F. Wishner, B. A. Seibel

Graduate School of Oceanography Faculty Publications

Shelled pteropods (Thecosomata) are a group of holoplanktonic mollusks that are believed to be especially sensitive to ocean acidification because their aragonitic shells are highly soluble. Despite this concern, there is very little known about the physiological response of these animals to conditions of elevated carbon dioxide. This study examines the oxygen consumption and ammonia excretion of five pteropod species, collected from tropical regions of the Pacific Ocean, to elevated levels of carbon dioxide (0.10 %, 1000 ppm). Our results show that pteropods that naturally migrate into oxygen minimum zones, such as Hyalocylis striata, Clio pyramidata, Cavolinia longirostris and Creseis …

The Good 5 Cent Cigar (2/1/2012), University Of Rhode Island

The Good 5 Cent Cigar (Student Newspaper Archives)

This is a digitized, downloadable version of the University of Rhode Island school newspaper.

I Can Intern In France! Student Perceptions Of Success During Their International Engineering Internship, Lars O. Erickson

Online Journal for Global Engineering Education

This article summarizes responses to an exit interview administered to French International Engineering Program (IEP) students at the University of Rhode Island (URI) upon return from their six-month internship in France. The goal is to determine what are the factors students attribute to their success during their engineering internship in France. The exit interview elicits information from students on their perceptions of : 1) their technical skills to do the engineering work required of them, 2) their French language skills in order to work on a day-to-day basis, and 3) their cross-cultural skills in order to bridge cultural differences. The …

2012-01-23 B.S. Program In Susatainability And Food Systems, Joanna Burkhardt

Library Impact Statements

This is the Library Impact Statement for the proposed B.S. Program in Sustainability and Food Systems. No new library resources are required to support this program.

Winter 2012 First Year Ra Training On Lgbtiqq Issues, Annie Russell

Lesbian Gay Bisexual Transgender Queer Center

This is the Winter 2012 First Year RA Training on LGBTIQQ Issues presented by Annie Russell.

Library Impact Statement For Bio 553 Regulatory Processes In Eucaryotic Cells, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for BIO 553 Regulatory Processes in Eucaryotic Cells new course proposal. No new library resources are needed to support this course. Responding library faculty member: Michael A. Cerbo II. Requesting faculty member: Joanna Norris.

Association Of The 5-Htt Gene-Linked Promoter Region (5-Httlpr) Polymorphism With Psychiatric Disorders: Review Of Psychopathology And Pharmacotherapy, George A. Kenna, Nick Roder-Hanna, Lorenzo Leggio, William H. Zywiak, James Clifford, Steven Edwards, John A. Kenna, Jessica Shoaff, Robert M. Swift

College of Nursing Faculty Publications

Serotonin (5-HT) regulates important biological and psychological processes including mood, and may be associated with the development of several psychiatric disorders. An association between psychopathology and genes that regulate 5-HT neurotransmission is a robust area of research. Identification of the genes responsible for the predisposition, development, and pharmacological response of various psychiatric disorders is crucial to the advancement of our understanding of their underlying neurobiology. This review highlights research investigating 5-HT transporter (5-HTTLPR) polymorphism, because studies investigating the impact of the 5-HTTLPR polymorphism have demonstrated significant associations with many psychiatric disorders. Decreased transcriptional activity of the S allele (“risk allele”) …

Library Impact Statement For Bio 485x Salt Marsh Ecology, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for BIO 485X Salt Marsh Ecology new course proposal. No new library resources are needed to support this course. Responding library faculty member: Michael A. Cerbo II. Requesting faculty member: Serena Moseman-Valtierra.

Library Impact Statement For Bio 585x Salt Marsh Ecology, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for BIO 585X Salt Marsh Ecology new course proposal. No new library resources are needed to support this course. Responding library faculty member: Michael A. Cerbo II. Requesting faculty member: Serena Moseman-Valtierra.

Library Impact Statement For Nrs 518 Ecohydrology, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for NRS 518 Ecohydrology new course proposal. No new library resources are needed to support this course. Responding library faculty member: Michael A. Cerbo II. Requesting facutly member: Arthur J. Gold.

False Ring Formation In Eastern Hemlock Branches: Impacts Of Hemlock Woolly Adelgid And Elongate Hemlock Scale, Liahna Gonda-King, Laura Radville, Evan L. Preisser

Biological Sciences Faculty Publications

Herbivores can alter plant physiology through the induction of abnormal wood formation. Feeding by some insects induces the formation of false rings, a band of thick-walled latewood cells within the earlywood portion of the tree ring that reduces water transport. Hemlock woolly adelgid (Adelges tsugae Annand) and elongate hemlock scale (Fiorinia externa Ferris) are invasive insects that both feed on eastern hemlock [Tsuga canadensis (L.) CarriÈre]. Adelges tsugae has a greater effect on tree health than F. externa, but the mechanism underlying their differential effect is unknown. We explored the effects of these herbivores by assessing growth ring formation in …

Enhanced Nrf2 Activity Worsens Insulin Resistance, Impairs Lipid Accumulation In Adipose Tissue, And Increases Hepatic Steatosis In Leptin-Deficient Mice, Jialin Xu, Supriya R. Kulkarni, Ajay C. Donepudi, Vijay R. More, Angela L. Slitt

Biomedical and Pharmaceutical Sciences Faculty Publications

The study herein determined the role of nuclear factor erythoid 2–related factor 2 (Nrf2) in the pathogenesis of hepatic steatosis, insulin resistance, obesity, and type 2 diabetes. Lep^ob/ob-Keap1-knockdown (KD) mice, which have increased Nrf2 activity, were generated. Markers of obesity and type 2 diabetes were measured in C57Bl/6J, Keap1-KD, Lep^ob/ob, and Lep^ob/ob-Keap1-KD mice. Lep^ob/ob-Keap1-KD mice exhibited less lipid accumulation, smaller adipocytes, decreased food intake, and reduced lipogenic gene expression. Enhanced Nrf2 activity impaired insulin signaling, prolonged hyperglycemia in response to glucose challenge, and induced insulin resistance in Lep^ob/ob background. Nrf2 augmented …

Division Of Research And Economic Development Annual Report For Fy2012, Uri Division Of Research And Economic Development

Reports (Research and Economic Development)

Annual report for the Division of Research and Economic Development of the University of Rhode Island for the year 2011-2012.

Includes statistics of project proposals, expenditures, URI Foundation Awards, previous annual report summaries and awards received by individual academic and administrative departments.