Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (28)
- Physical Sciences and Mathematics (28)
- Engineering (26)
- Psychiatry and Psychology (24)
- Life Sciences (18)
-
- Marine Biology (11)
- Biology (6)
- Business (4)
- Tourism and Travel (4)
- Education (3)
- Social and Behavioral Sciences (2)
- Aerospace Engineering (1)
- Anthropology (1)
- Art and Design (1)
- Arts and Humanities (1)
- Chemistry (1)
- Cognitive Science (1)
- Dance (1)
- Disability and Equity in Education (1)
- East Asian Languages and Societies (1)
- Educational Methods (1)
- Educational Psychology (1)
- Educational Sociology (1)
- English Language and Literature (1)
- Environmental Sciences (1)
- Film and Media Studies (1)
- Gender Equity in Education (1)
- Gender and Sexuality (1)
- Interdisciplinary Arts and Media (1)
- Japanese Studies (1)
- Keyword
-
- Humans (142)
- Animals (92)
- Female (59)
- Climate change (58)
- Male (58)
-
- Biodiversity (50)
- Adult (35)
- Aquaculture (35)
- Conservation (34)
- Ecology (32)
- Middle Aged (31)
- Ecosystem (29)
- Microplastics (24)
- Fish (23)
- Marine (23)
- Models (22)
- Aged (20)
- Behaviour (20)
- Meningioma (20)
- Ocean acidification (20)
- Young Adult (20)
- Microplastic (19)
- Biogeography (18)
- Climate Change (18)
- Education (18)
- Sustainability (18)
- Ecosystem services (17)
- Environment (17)
- Fisheries (17)
- Hypoxia (17)
- Publication Year
- Publication
-
- School of Biological and Marine Sciences (2062)
- School of Geography, Earth and Environmental Sciences (631)
- Peninsula Medical School (536)
- School of Biological and Marine Sciences Theses (432)
- School of Engineering, Computing and Mathematics (388)
-
- School of Psychology (343)
- School of Biomedical Sciences (341)
- The Plymouth Student Scientist (281)
- School of Geography, Earth and Environmental Sciences Theses (215)
- Other Faculty of Science and Engineering Theses (201)
- School of Health Professions (158)
- School of Art, Design and Architecture (144)
- School of Engineering, Computing and Mathematics Theses (115)
- School of Nursing and Midwifery (110)
- Peninsula Dental School (107)
- Other Faculty of Health Theses (93)
- Other Faculty of Arts, Humanities and Business Theses (92)
- School of Law, Humanities and Social Sciences (62)
- School of Psychology Theses (52)
- More Faculty of Science and Engineering Research (45)
- Plymouth Business School (42)
- More Faculty of Health Research (39)
- Peninsula Medical School Theses (35)
- School of Art, Design and Architecture Theses (35)
- School of Law, Humanities and Social Sciences Theses (34)
- Plymouth Institute of Education (26)
- Faculty of Science and Engineering Datasets (22)
- Plymouth Business School Theses (21)
- School of Biomedical Sciences Theses (19)
- The Plymouth Law and Criminal Justice Review (19)
- Publication Type
- File Type
Articles 3031 - 3060 of 6798
Full-Text Articles in Entire DC Network
When Punishment Is Emotion-Driven: Children’S, Adolescents’, And Adults’ Costly Punishment Of Unfair Allocations, M Gummerum, B Lopez-Perez, E Van Dijk, Lf Van Dillen
When Punishment Is Emotion-Driven: Children’S, Adolescents’, And Adults’ Costly Punishment Of Unfair Allocations, M Gummerum, B Lopez-Perez, E Van Dijk, Lf Van Dillen
School of Psychology
When do children, adolescents, and adults decide to punish fairness violations? Two studies with 9-year-old children, 13-year-old adolescents, and adults investigated whether the link between unfairness and punishment was mediated by negative emotional reactions (measured through galvanic skin responses and emotion ratings). Study 1 (N = 117) examined this question in the context of second-party punishment, where the punisher is a direct victim of the violation. Study 2 (N = 119) assessed third-party punishment, where the punisher is an observer, unaffected by the violation. In each study, participants were presented with seven distributions of points, which differed in how fairly …
Reverse Engineering Field-Derived Vertical Distribution Profiles To Infer Larval Swimming Behaviors, M. K. James, J. A. Polton, A. R. Brereton, K. L. Howell, W. A.M. Nimmo-Smith, A. M. Knights
Reverse Engineering Field-Derived Vertical Distribution Profiles To Infer Larval Swimming Behaviors, M. K. James, J. A. Polton, A. R. Brereton, K. L. Howell, W. A.M. Nimmo-Smith, A. M. Knights
School of Biological and Marine Sciences
Biophysical models are well-used tools for predicting the dispersal of marine larvae. Larval behavior has been shown to influence dispersal, but how to incorporate behavior effectively within dispersal models remains a challenge. Mechanisms of behavior are often derived from laboratory-based studies and therefore, may not reflect behavior in situ. Here, using state-of-the-art models, we explore the movements that larvae must undertake to achieve the vertical distribution patterns observed in nature. Results suggest that behaviors are not consistent with those described under the tidally synchronized vertical migration (TVM) hypothesis. Instead, we show (i) a need for swimming speed and direction to …
Exploring Mechanisms For Spring Bloom Evolution: Contrasting 2008 And 2012 Blooms In The Southwest Pacific Ocean, Stephen M. Chiswell, Karl A. Safi, Sylvia G. Sander, Robert Strzepek, Michael J. Ellwood, Angela Milne, Philip W. Boyd
Exploring Mechanisms For Spring Bloom Evolution: Contrasting 2008 And 2012 Blooms In The Southwest Pacific Ocean, Stephen M. Chiswell, Karl A. Safi, Sylvia G. Sander, Robert Strzepek, Michael J. Ellwood, Angela Milne, Philip W. Boyd
School of Geography, Earth and Environmental Sciences
No abstract provided.
A Change Of Mind: Applying Social And Behavioral Research Methods To The Assessment Of The Effectiveness Of Ocean Literacy Initiatives, Matthew Ashley, Sabine Pahl, Gillian Glegg, Stephen Fletcher
A Change Of Mind: Applying Social And Behavioral Research Methods To The Assessment Of The Effectiveness Of Ocean Literacy Initiatives, Matthew Ashley, Sabine Pahl, Gillian Glegg, Stephen Fletcher
School of Psychology
No abstract provided.
Linking Direct Measurements Of Turbidity Currents To Submarine Canyon-Floor Deposits, Katherine L. Maier, Jennifer A. Gales, Charles K. Paull, Kurt Rosenberger, Peter J. Talling, Stephen M. Simmons, Roberto Gwiazda, Mary Mcgann, Matthieu J.B. Cartigny, Eve Lundsten, Krystle Anderson, Michael A. Clare, Jingping Xu, D Parson, James P. Barry, Monica Wolfson-Schwehr, Nora M. Nieminski, Esther J. Sumner, Monterey Coordinated Canyon Experiment Team
Linking Direct Measurements Of Turbidity Currents To Submarine Canyon-Floor Deposits, Katherine L. Maier, Jennifer A. Gales, Charles K. Paull, Kurt Rosenberger, Peter J. Talling, Stephen M. Simmons, Roberto Gwiazda, Mary Mcgann, Matthieu J.B. Cartigny, Eve Lundsten, Krystle Anderson, Michael A. Clare, Jingping Xu, D Parson, James P. Barry, Monica Wolfson-Schwehr, Nora M. Nieminski, Esther J. Sumner, Monterey Coordinated Canyon Experiment Team
School of Biological and Marine Sciences
No abstract provided.
Mitochondrial Activity And Skeletal Muscle Insulin Resistance In Kidney Disease, Jane E. Carré, C Affourtit
Mitochondrial Activity And Skeletal Muscle Insulin Resistance In Kidney Disease, Jane E. Carré, C Affourtit
School of Biomedical Sciences
Insulin resistance is a key feature of the metabolic syndrome, a cluster of medical disorders that together increase the chance of developing type 2 diabetes and cardiovascular disease. In turn, type 2 diabetes may cause complications such as diabetic kidney disease (DKD). Obesity is a major risk factor for developing systemic insulin resistance, and skeletal muscle is the first tissue in susceptible individuals to lose its insulin responsiveness. Interestingly, lean individuals are not immune to insulin resistance either. Non-obese, non-diabetic subjects with chronic kidney disease (CKD), for example, exhibit insulin resistance at the very onset of CKD, even before clinical …
Quantifying Susceptibility Of Marine Invertebrate Biocomposites To Dissolution In Reduced Ph, Matthew Chadwick, Elizabeth M. Harper, Anaëlle Lemasson, John I. Spicer, Lloyd S. Peck
Quantifying Susceptibility Of Marine Invertebrate Biocomposites To Dissolution In Reduced Ph, Matthew Chadwick, Elizabeth M. Harper, Anaëlle Lemasson, John I. Spicer, Lloyd S. Peck
School of Biological and Marine Sciences
No abstract provided.
Correction: Ocean Acidification At A Coastal Co2 Vent Induces Expression Of Stress-Related Transcripts And Transposable Elements In The Sea Anemone Anemonia Viridis, Ilona Urbarova, Sylvain Forêt, Åse Emblem, Marco Milazzo, Jason Hall-Spencer
Correction: Ocean Acidification At A Coastal Co2 Vent Induces Expression Of Stress-Related Transcripts And Transposable Elements In The Sea Anemone Anemonia Viridis, Ilona Urbarova, Sylvain Forêt, Åse Emblem, Marco Milazzo, Jason Hall-Spencer
School of Biological and Marine Sciences
[This corrects the article DOI: 10.1371/journal.pone.0210358.].
A Nonlinear Approach To Generate Creative Data Using Physarum Polycephalum-Based Memristors, S Venkatesh, E Braund, E Miranda
A Nonlinear Approach To Generate Creative Data Using Physarum Polycephalum-Based Memristors, S Venkatesh, E Braund, E Miranda
School of Art, Design and Architecture
No abstract provided.
A Disclosure Gel For Visual Detection Of Livebacillus Anthracisspores, Cv Robinson, Ah Bishop
A Disclosure Gel For Visual Detection Of Livebacillus Anthracisspores, Cv Robinson, Ah Bishop
School of Biological and Marine Sciences
Aims To develop a gel formulation to trigger a visual signal for rapid disclosure of the location and extent of surface contamination with viable Bacillus anthracis spores. Methods and Results Methylumbelliferyl-a-D-glucopyranoside was combined with hyaluronic acid to produce a gel that could be applied to a surface as a coating. It remained hydrated for a sufficient time for a-glucosidase activity present in intact B. anthracis spores to cleave the substrate and release the fluorescent product, methylumbelliferone. The presence of B. anthracis spores could be disclosed at 5 × 104 CFU per reaction test well (0·32 cm2) both visually and using …
Role Of Recent Climate Change On Carbon Sequestration In Peatland Systems., Paul H. Lunt, Ralph M. Fyfe, Alan D. Tappin
Role Of Recent Climate Change On Carbon Sequestration In Peatland Systems., Paul H. Lunt, Ralph M. Fyfe, Alan D. Tappin
School of Geography, Earth and Environmental Sciences
This paper provides information on the impact of recent climate change on carbon sequestration in peatland systems in South West England. This is important because peatlands have the potential to sequester and hold large quantities of anthropogenically released CO2. This paper investigates whether there has been a reduction in the strength of carbon sinks in a valley mire and blanket bog, which occur on the limits of the biogeographical envelop for peatlands in Britain. Past rates of carbon accumulation were calculated from peat depth and the sequential analysis of peat age, bulk density and carbon content from cores taken from …
Cadmium And/Or Copper Excess Induce Interdependent Metal Accumulation, Dna Methylation, Induction Of Metal Chelators And Antioxidant Defences In The Seagrass Zostera Marina, M Greco, Ca Saez, Ra Contreras, Et Al
Cadmium And/Or Copper Excess Induce Interdependent Metal Accumulation, Dna Methylation, Induction Of Metal Chelators And Antioxidant Defences In The Seagrass Zostera Marina, M Greco, Ca Saez, Ra Contreras, Et Al
School of Biological and Marine Sciences
In this investigation, we assessed the effects of Cu and/or Cd excess on physiological and metabolic processes of the widespread seagrass Zostera marina. Adult were exposed to low Cd and Cu (0.89 and 0.8 µM, respectively) and high Cd and Cu (8.9 and 2.4 µM, respectively) for 6 d at: Control conditions; low Cu; high Cu; low Cd; high Cd; low Cd and low Cu; and high Cd and high Cu. Photosynthetic performance decreased under single and combined treatments, although effects were more negative under Cu than Cd. Total Cu accumulation was higher than Cd, under single and combined treatments; …
The Oral Nitrate-Reducing Capacity Correlates With Peak Power Output And Peak Oxygen Uptake In Healthy Humans., B. Thomas, S. Smallwood, C. Clarke, R. Bescos
The Oral Nitrate-Reducing Capacity Correlates With Peak Power Output And Peak Oxygen Uptake In Healthy Humans., B. Thomas, S. Smallwood, C. Clarke, R. Bescos
School of Health Professions
Interest in inorganic nitrate and nitrite has grown substantially over the past decade as research has revealed the role of these anions in enhancing nitric oxide (NO) availability through an oral pathway. Nitrite synthesis in the mouth seems to be an important mechanism to feed the circulatory system with this anion. This is interesting since greater plasma nitrite concentration has been associated with better fitness levels in humans, but this question has not been investigated in relation to salivary nitrite concentration. Additionally, no previous study has investigated the oral nitrate-reducing capacity in regards to peak oxygen uptake (VO2peak) or peak …
Southern High-Latitude Warmth During The Jurassic–Cretaceous: New Evidence From Clumped Isotope Thermometry, Madeleine L. Vickers, David Bajnai, Gregory D. Price, Jolien Linckens, Jens Fiebig
Southern High-Latitude Warmth During The Jurassic–Cretaceous: New Evidence From Clumped Isotope Thermometry, Madeleine L. Vickers, David Bajnai, Gregory D. Price, Jolien Linckens, Jens Fiebig
School of Geography, Earth and Environmental Sciences
No abstract provided.
Macrophage Subsets Exhibit Distinct E. Coli-Lps Tolerisable Cytokines Associated With The Negative Regulators, Irak-M And Tollip, Khalid Al-Shaghdali, Barbara Durante, Christopher Hayward, Jane Beal, Andrew Foey
Macrophage Subsets Exhibit Distinct E. Coli-Lps Tolerisable Cytokines Associated With The Negative Regulators, Irak-M And Tollip, Khalid Al-Shaghdali, Barbara Durante, Christopher Hayward, Jane Beal, Andrew Foey
School of Biomedical Sciences
No abstract provided.
Oral Bovine Colostrum Supplementation Does Not Increase Circulating Insulin-Like Growth Factor-1 Concentration In Healthy Adults: Results From Short- And Long-Term Administration Studies, G Davison, Aw Jones, T Marchbank, Rj Playford
Oral Bovine Colostrum Supplementation Does Not Increase Circulating Insulin-Like Growth Factor-1 Concentration In Healthy Adults: Results From Short- And Long-Term Administration Studies, G Davison, Aw Jones, T Marchbank, Rj Playford
Peninsula Medical School
PURPOSE: Bovine colostrum is available in health food shops and as a sports food supplement and is rich in antibodies and growth factors including IGF-1. World Anti-Doping Agency advises athletes against taking colostrum for fear of causing increased plasma IGF-1. There are also concerns that colostrum may theoretically stimulate malignancy in organs which express IGF-1 receptors. We, therefore, determined changes in plasma IGF-1 levels in subjects taking colostrum or placebo for 1 day, 4 weeks, and 12 weeks. METHODS: Plasma IGF1 levels were determined in healthy males (n = 16) who ingested 40 g bovine colostrum or placebo along with …
Correction To: Particle Toxicology And Health - Where Are We?, M Riediker, D Zink, W Kreyling, G Oberdörster, A Elder, U Graham, I Lynch, A Duschl, G Ichihara, S Ichihara, T Kobayashi, N Hisanaga, M Umezawa, T-J Cheng, R Handy, M Gulumian, S Tinkle, F Cassee
Correction To: Particle Toxicology And Health - Where Are We?, M Riediker, D Zink, W Kreyling, G Oberdörster, A Elder, U Graham, I Lynch, A Duschl, G Ichihara, S Ichihara, T Kobayashi, N Hisanaga, M Umezawa, T-J Cheng, R Handy, M Gulumian, S Tinkle, F Cassee
School of Biological and Marine Sciences
No abstract provided.
New Mediterranean Biodiversity Records (April, 2019), V Kousteni, R Bakiu, A Benhmida, Et Al
New Mediterranean Biodiversity Records (April, 2019), V Kousteni, R Bakiu, A Benhmida, Et Al
School of Biological and Marine Sciences
The Collective Article on “New Mediterranean Biodiversity Records” offers the means to publish biodiversity records in the Mediterranean Sea. The current article presents new biodiversity data information on 18 taxa (14 alien, 3 native and 1 cryptogenic species) belonging to 5 Phyla that are reported for 11 different countries listed according to their geographic position from the western to the eastern Mediterranean Sea. Algeria: the alien green alga Caulerpa taxifolia var. distichophylla and the heterobranchs Aplysia dactylomeda and Aplysia punctata are first reported from the entire country. France: a new record of the alien hydroid Porpita porpita is reported from …
Chronosequence Of Former Kaolinite Open Cast Mines Suggests Active Intervention Is Required For The Restoration Of Atlantic Heathland, Mary Lane, Mick E. Hanley, Paul Lunt, Mairi E. Knight, Charlotte B. Braungardt, Jonathan S. Ellis
Chronosequence Of Former Kaolinite Open Cast Mines Suggests Active Intervention Is Required For The Restoration Of Atlantic Heathland, Mary Lane, Mick E. Hanley, Paul Lunt, Mairi E. Knight, Charlotte B. Braungardt, Jonathan S. Ellis
School of Biological and Marine Sciences
Atlantic lowland heath (ALH) is a priority conservation habitat in Western Europe, but restoration efforts have met with mixed success due to the complexity associated with replicating establishment conditions. By virtue of their impoverished, often acidic soils and geographic location in areas naturally occupied by ALH communities, former kaolinite mine sites may offer an excellent opportunity for heathland restoration. Using a chronosequence of former open cast kaolinite mines in South West England (0, 2, 27, and 150 years since mining ceased), we determined the ability of ALH vegetation and soils to reestablish naturally and in addition, for the three youngest …
Integrating Local Ecological Knowledge, Citizen Science And Long‐Term Historical Data For Endangered Species Conservation: Additional Records Of Angel Sharks (Chondrichthyes: Squatinidae) In The Mediterranean Sea, I Giovos, V Stoilas, Saa Al‐Mabruk, N Doumpas, Et Al
Integrating Local Ecological Knowledge, Citizen Science And Long‐Term Historical Data For Endangered Species Conservation: Additional Records Of Angel Sharks (Chondrichthyes: Squatinidae) In The Mediterranean Sea, I Giovos, V Stoilas, Saa Al‐Mabruk, N Doumpas, Et Al
School of Biological and Marine Sciences
All three species of angel sharks (genus Squatina) inhabiting the Mediterranean Sea are listed as Critically Endangered in the International Union for Conservation of Nature Red List of Threatened Species due to overexploitation. New records from Cyprus, Greece, Italy and Libya were collected from citizen-scientists and integrated with local knowledge obtained using structured interviews in the four countries. Observations and reports, together with an analysis of the reconstructed fisheries data, resulted in the identification of areas of interest, a review of the illegal trade of the species and a debate about the credibility of fisheries data for assessing threatened and/or …
Multilayered Composite Coatings Of Titanium Dioxide Nanotubes Decorated With Zinc Oxide And Hydroxyapatite Nanoparticles: Controlled Release Of Zn And Antimicrobial Properties Against Staphylococcus Aureus, Urvashi F. Gunputh, Huirong Le, Alexandros Besinis, Christopher Tredwin, Richard D. Handy
Multilayered Composite Coatings Of Titanium Dioxide Nanotubes Decorated With Zinc Oxide And Hydroxyapatite Nanoparticles: Controlled Release Of Zn And Antimicrobial Properties Against Staphylococcus Aureus, Urvashi F. Gunputh, Huirong Le, Alexandros Besinis, Christopher Tredwin, Richard D. Handy
School of Engineering, Computing and Mathematics
No abstract provided.
Simultaneous Detection Of Alkylamines In The Surface Ocean And Atmosphere Of The Antarctic Sympagic Environment, M Dall’Osto, Ruth L. Airs, Rachael Beale, Charlotte Cree, Mark F. Fitzsimons, David Beddows, Roy M. Harrison, Darius Ceburnis, C O’Dowd, Matteo Rinaldi, Marco Paglione, Athanasios Nenes, Stefano Decesari, Rafel Simó
Simultaneous Detection Of Alkylamines In The Surface Ocean And Atmosphere Of The Antarctic Sympagic Environment, M Dall’Osto, Ruth L. Airs, Rachael Beale, Charlotte Cree, Mark F. Fitzsimons, David Beddows, Roy M. Harrison, Darius Ceburnis, C O’Dowd, Matteo Rinaldi, Marco Paglione, Athanasios Nenes, Stefano Decesari, Rafel Simó
School of Engineering, Computing and Mathematics
Measurements of alkylamines from seawater and atmospheric samples collected simultaneously across the Antarctic Peninsula, South Orkney and South Georgia Islands are reported. Concentrations of mono-, di- and trimethylamine (MMA, DMA and TMA, respectively), and their precursors, the quarternary amines glycine betaine and choline, were enhanced in sympagic sea water samples relative to ice-devoid pelagic ones, suggesting the microbiota of sea ice and sea ice-influenced ocean is a major source of these compounds. Primary sea-spray aerosol particles artificially generated by bubbling seawater samples were investigated by Aerosol Time-Of-Flight Mass Spectrometry (ATOFMS) of single particles; their mixing state indicated that alkylamines were …
Trace Elements In Laundry Dryer Lint: A Proxy For Household Contamination And Discharges To Waste Water., Andrew Turner
Trace Elements In Laundry Dryer Lint: A Proxy For Household Contamination And Discharges To Waste Water., Andrew Turner
School of Geography, Earth and Environmental Sciences
Seventy samples of laundry dryer lint from 19 households have been analysed for trace elements (As, Br, Cu, Fe, Ni, Pb, Sb, Zn) by energy-dispersive portable X-ray fluorescence (XRF) spectrometry. Bromine, Fe and Zn were detected in more than sixty samples encompassing all households, with dry weight concentrations ranging from 5.5 to 213 μg g-1, 76 to 3580 μg g-1 and 24 to 3540 μg g-1, respectively. Lead and Sb were detected in twenty and eight samples from ten and seven households, respectively, with concentrations ranging from about 8 to 110 μg g-1 for Pb and 40 to 90 μg …
Tools And Rules For Modelling Uptake And Bioaccumulation Of Nanomaterials In Invertebrate Organisms, Den Brink Nw Van, Kokalj A Jemec, Pv Silva, E Lahive, K Norrfors, M Baccaro, Z Khodaparast, S Loureiro, D Drobne, G Cornelis, S Lofts, Rd Handy, C Svendsen, D Spurgeon, Gestel Cam Van
Tools And Rules For Modelling Uptake And Bioaccumulation Of Nanomaterials In Invertebrate Organisms, Den Brink Nw Van, Kokalj A Jemec, Pv Silva, E Lahive, K Norrfors, M Baccaro, Z Khodaparast, S Loureiro, D Drobne, G Cornelis, S Lofts, Rd Handy, C Svendsen, D Spurgeon, Gestel Cam Van
School of Biological and Marine Sciences
Quantification of the uptake and elimination of nanomaterials (NMs) by organisms is key in assessing the environmental risks of NMs.
Volatile And Semi-Volatile Components Of Jetsam Ambergris, Michael J. Wilde, William J. Robson, Paul A. Sutton, Steven J. Rowland
Volatile And Semi-Volatile Components Of Jetsam Ambergris, Michael J. Wilde, William J. Robson, Paul A. Sutton, Steven J. Rowland
School of Geography, Earth and Environmental Sciences
No abstract provided.
A Phase Iii Trial Of Tirasemtiv As A Potential Treatment For Amyotrophic Lateral Sclerosis, On Behalf Of The Vitality-Als Study Group, Jeremy M. Shefner, Merit E. Cudkowicz, Orla Hardiman, Bettina M. Cockroft, Jacqueline H. Lee, Fady I. Malik, Lisa Meng, Stacy A. Rudnicki, Andrew A. Wolff, Jinsy A. Andrews, Oliver Hanemann
A Phase Iii Trial Of Tirasemtiv As A Potential Treatment For Amyotrophic Lateral Sclerosis, On Behalf Of The Vitality-Als Study Group, Jeremy M. Shefner, Merit E. Cudkowicz, Orla Hardiman, Bettina M. Cockroft, Jacqueline H. Lee, Fady I. Malik, Lisa Meng, Stacy A. Rudnicki, Andrew A. Wolff, Jinsy A. Andrews, Oliver Hanemann
Peninsula Medical School
Objective: To assess the efficacy of tirasemtiv, a fast skeletal muscle troponin activator, vs. placebo in patients with amyotrophic lateral sclerosis. Methods: VITALITY-ALS (NCT02496767) was a multinational, double-blind, randomized, placebo-controlled clinical trial. Participants tolerating 2 weeks of open-label tirasemtiv (125 mg twice daily) were randomized 3:2:2:2 to placebo or one of three target tirasemtiv dose levels, using an escalating dosage protocol lasting 28 days. The primary outcome measure was changed in slow vital capacity (SVC) at 24 weeks. Secondary endpoints included a change in muscle strength and time to respiratory milestones of disease progression. Results: Of 744 participants, 565 tolerated …
Behavioural Interdependence In A Shrimp‐Goby Mutualism, A. L. Burns, A. D.M. Wilson, A. J.W. Ward
Behavioural Interdependence In A Shrimp‐Goby Mutualism, A. L. Burns, A. D.M. Wilson, A. J.W. Ward
School of Biological and Marine Sciences
No abstract provided.
Storm Waves At The Shoreline: When And Where Are Infragravity Waves Important?, Oliver Billson, Paul Russell, Mark Davidson
Storm Waves At The Shoreline: When And Where Are Infragravity Waves Important?, Oliver Billson, Paul Russell, Mark Davidson
School of Biological and Marine Sciences
Infragravity waves (frequency, f = 0.005–0.05 Hz) are known to dominate hydrodynamic and sediment transport processes close to the shoreline on low-sloping sandy beaches, especially when incident waves are large. However, in storm wave conditions, how their importance varies on different beach types, and with different mixes of swell and wind-waves is largely unknown. Here, a new dataset, comprising shoreline video observations from five contrasting sites (one low-sloping sandy beach, two steep gravel beaches, and two compound/mixed sand and gravel beaches), under storm wave conditions (deep water wave height, H0 up to 6.6 m, and peak period, Tp up to …
Ocean Acidification Impacts On Coastal Ecosystem Services Due To Habitat Degradation, Jason M. Hall-Spencer, Ben P. Harvey
Ocean Acidification Impacts On Coastal Ecosystem Services Due To Habitat Degradation, Jason M. Hall-Spencer, Ben P. Harvey
School of Biological and Marine Sciences
No abstract provided.
Identification, Origin And Characteristics Of Bio-Bead Microplastics From Beaches In Western Europe., Andrew Turner, Claire Wallerstein, Rob Arnold
Identification, Origin And Characteristics Of Bio-Bead Microplastics From Beaches In Western Europe., Andrew Turner, Claire Wallerstein, Rob Arnold
School of Geography, Earth and Environmental Sciences
Primary microplastics have been collected from 17 beaches along the Atlantic, English Channel and southern North Sea coasts of western Europe. Based on visual characteristics, these plastics were differentiated as either relatively smooth, lentil- or disc-shaped pre-production pellets (or nurdles), which were usually a few mm in diameter and were mainly white to off-white, or rougher and more irregular pellets that were slightly larger and usually black. The latter appeared to be bio-beads, or plastics that are specifically manufactured for use as biomedia in certain sewage water treatment (SWT) plants and, possibly, in other industrial wastewater treatment applications. Identification of …