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Articles 2821 - 2850 of 6792
Full-Text Articles in Entire DC Network
Plastic Debris In The Marine Environment: History And Future Challenges, Imogen Ellen Napper, Richard C. Thompson
Plastic Debris In The Marine Environment: History And Future Challenges, Imogen Ellen Napper, Richard C. Thompson
School of Biological and Marine Sciences
No abstract provided.
An Overview Of Physical Risks In The Mt. Everest Region, Kimberley R. Miner, Paul A. Mayewski, Saraju K. Baidya, Kenneth Broad, Heather Clifford, Aurora Elmore, Ananta P. Gajurel, Bibek Giri, Sam Guilford, Mary Hubbard, Corey Jaskolski, Heather Koldewey, Wei Li, Tom Matthews, Imogen Napper, L. Baker Perry, Mariusz Potocki, John C. Priscu, Alex Tait, Richard Thompson, Subash Tuladhar
An Overview Of Physical Risks In The Mt. Everest Region, Kimberley R. Miner, Paul A. Mayewski, Saraju K. Baidya, Kenneth Broad, Heather Clifford, Aurora Elmore, Ananta P. Gajurel, Bibek Giri, Sam Guilford, Mary Hubbard, Corey Jaskolski, Heather Koldewey, Wei Li, Tom Matthews, Imogen Napper, L. Baker Perry, Mariusz Potocki, John C. Priscu, Alex Tait, Richard Thompson, Subash Tuladhar
School of Biological and Marine Sciences
No abstract provided.
Occurrence And Assemblage Composition Of Intertidal Non-Native Species May Be Influenced By Shipping Patterns And Artificial Structures, Kathryn A. O'Shaughnessy, Stephen J. Hawkins, Anna L.E. Yunnie, Mick E. Hanley, Paul Lunt, Richard C. Thompson, Louise B. Firth
Occurrence And Assemblage Composition Of Intertidal Non-Native Species May Be Influenced By Shipping Patterns And Artificial Structures, Kathryn A. O'Shaughnessy, Stephen J. Hawkins, Anna L.E. Yunnie, Mick E. Hanley, Paul Lunt, Richard C. Thompson, Louise B. Firth
School of Biological and Marine Sciences
Habitat modification coupled with the spread of non-native species (NNS) are among the top threats to marine biodiversity globally. Species are known to be transported to new locations via international shipping and secondarily spread via regional vessels and artificial structures. Rapid Assessment Surveys (RAS) combining quantitative and semi-quantitative methods compared NNS richness and assemblage composition on intertidal natural rocky shores and artificial structures in harbours in different regions along the south coast of England. Quantitative data showed that artificial habitats supported higher richness than natural habitats, while semi-quantitative data found no difference in richness among habitat types. This result was …
Applicability, Safety, And Biological Activity Of Regulatory T Cell Therapy In Liver Transplantation, A Sánchez‐Fueyo, Gavin Whitehouse, Nathali Grageda, Matthew E. Cramp, Tiong Y. Lim, Marco Romano, Sarah Thirkell, Katie Lowe, Laura Fry, Julie Heward, Alex Kerr, Jakia Ali, Chris Fisher, Gillian Lewis, Andrew Hope, Elisavet Kodela, Mike Lyne, Farzin Farzaneh, Shahram Kordasti, I Rebollo‐Mesa, Lozano J Jose, Niloufar Safinia, Nigel Heaton, Robert Lechler, M Martínez‐Llordella, Giovanna Lombardi
Applicability, Safety, And Biological Activity Of Regulatory T Cell Therapy In Liver Transplantation, A Sánchez‐Fueyo, Gavin Whitehouse, Nathali Grageda, Matthew E. Cramp, Tiong Y. Lim, Marco Romano, Sarah Thirkell, Katie Lowe, Laura Fry, Julie Heward, Alex Kerr, Jakia Ali, Chris Fisher, Gillian Lewis, Andrew Hope, Elisavet Kodela, Mike Lyne, Farzin Farzaneh, Shahram Kordasti, I Rebollo‐Mesa, Lozano J Jose, Niloufar Safinia, Nigel Heaton, Robert Lechler, M Martínez‐Llordella, Giovanna Lombardi
Peninsula Medical School
Regulatory T cells (Tregs) are a lymphocyte subset with intrinsic immunosuppressive properties that can be expanded in large numbers ex vivo and have been shown to prevent allograft rejection and promote tolerance in animal models. To investigate the safety, applicability, and biological activity of autologous Treg adoptive transfer in humans, we conducted an open-label, dose-escalation, Phase I clinical trial in liver transplantation. Patients were enrolled while awaiting liver transplantation or 6-12 months posttransplant. Circulating Tregs were isolated from blood or leukapheresis, expanded under good manufacturing practices (GMP) conditions, and administered intravenously at either 0.5-1 million Tregs/kg or 3-4.5 million Tregs/kg. …
The Development Of A 3d Computational Mesh To Improve The Representation Of Dynamic Processes: The Black Sea Test Case, Diego Bruciaferri, Georgy Shapiro, Sergey Stanichny, Andrey Zatsepin, Tal Ezer, Fred Wobus, Xavier Francis, Dan Hilton
The Development Of A 3d Computational Mesh To Improve The Representation Of Dynamic Processes: The Black Sea Test Case, Diego Bruciaferri, Georgy Shapiro, Sergey Stanichny, Andrey Zatsepin, Tal Ezer, Fred Wobus, Xavier Francis, Dan Hilton
School of Biological and Marine Sciences
No abstract provided.
Tyre Wear Particles: An Abundant Yet Widely Unreported Microplastic?, Lydia J. Knight, Florence N.F. Parker-Jurd, Maya Al-Sid-Cheikh, Richard C. Thompson
Tyre Wear Particles: An Abundant Yet Widely Unreported Microplastic?, Lydia J. Knight, Florence N.F. Parker-Jurd, Maya Al-Sid-Cheikh, Richard C. Thompson
School of Biological and Marine Sciences
No abstract provided.
Predicting Beach Rotation Using Multiple Atmospheric Indices, Mark Wiggins, Tim Scott, Gerd Masselink, R. Jak Mccarroll, Paul Russell
Predicting Beach Rotation Using Multiple Atmospheric Indices, Mark Wiggins, Tim Scott, Gerd Masselink, R. Jak Mccarroll, Paul Russell
School of Biological and Marine Sciences
No abstract provided.
Gone With The Wind: Seasonal Distribution And Habitat Use By The Reef Manta Ray ( Mobula Alfredi ) In The Maldives, Implications For Conservation, Joanna L. Harris, Peter K. Mcgregor, Yvonne Oates, Guy M.W. Stevens
Gone With The Wind: Seasonal Distribution And Habitat Use By The Reef Manta Ray ( Mobula Alfredi ) In The Maldives, Implications For Conservation, Joanna L. Harris, Peter K. Mcgregor, Yvonne Oates, Guy M.W. Stevens
School of Biological and Marine Sciences
Reef manta rays (Mobula alfredi) are one of the ocean's largest and most charismatic species. Pressure from targeted and bycatch fisheries coupled with their conservative life-history traits including slow growth, late maturity, and low fecundity has led to catastrophic declines of the global population. The species is now listed as Vulnerable to Extinction on IUCN Red List of Threatened Species. The global M. alfredi population is widely distributed in highly fragmented subpopulations. The Maldives supports the world's largest known subpopulation that undergoes seasonal migrations which are thought to be linked to peaks in ocean productivity induced by the South Asian …
Plant Volatiles Induced By Herbivore Eggs Prime Defences And Mediate Shifts In The Reproductive Strategy Of Receiving Plants, Foteini G. Pashalidou, Lisa Eyman, James Sims, James Buckley, Nina E. Fatouros, Moraes Cm De, Mark C. Mescher
Plant Volatiles Induced By Herbivore Eggs Prime Defences And Mediate Shifts In The Reproductive Strategy Of Receiving Plants, Foteini G. Pashalidou, Lisa Eyman, James Sims, James Buckley, Nina E. Fatouros, Moraes Cm De, Mark C. Mescher
School of Biological and Marine Sciences
No abstract provided.
The Impact Of Potting For Crustaceans On Temperate Rocky Reef Habitats: Implications For Management, Sarah C. Gall, Lynda D. Rodwell, Sarah Clark, Tim Robbins, Martin J. Attrill, Luke A. Holmes, Emma V. Sheehan
The Impact Of Potting For Crustaceans On Temperate Rocky Reef Habitats: Implications For Management, Sarah C. Gall, Lynda D. Rodwell, Sarah Clark, Tim Robbins, Martin J. Attrill, Luke A. Holmes, Emma V. Sheehan
School of Biological and Marine Sciences
No abstract provided.
Sandy Beaches Can Survive Sea-Level Rise, J. A.G. Cooper, G. Masselink, G. Coco, A. D. Short, B. Castelle, K. Rogers, E. Anthony, A. N. Green, J. T. Kelley, O. H. Pilkey, D. W.T. Jackson
Sandy Beaches Can Survive Sea-Level Rise, J. A.G. Cooper, G. Masselink, G. Coco, A. D. Short, B. Castelle, K. Rogers, E. Anthony, A. N. Green, J. T. Kelley, O. H. Pilkey, D. W.T. Jackson
School of Biological and Marine Sciences
Vousdoukas et al. assert that global sea-level rise (SLR) poses a threat to the existence of sandy beaches. They use global databases of sandy beaches, bathymetry and wave conditions to drive a simple model based on the Bruun rule to quantify shoreline retreat, to which they add a background ambient trend based on satellite data. When retreat is more than 100 m by 2100, they declare those beaches near extinct by the end of the century. We feel that this is an incorrect and potentially damaging finding. Critical to the paper’s conclusions is the fact that, provided that accommodation space …
Ocean Acidification Alters Bacterial Communities On Marine Plastic Debris, Ben P. Harvey, Dorsaf Kerfahi, Yeon Gyun Jung, Jae Ho Shin, Jonathan M. Adams, Jason M. Hall-Spencer
Ocean Acidification Alters Bacterial Communities On Marine Plastic Debris, Ben P. Harvey, Dorsaf Kerfahi, Yeon Gyun Jung, Jae Ho Shin, Jonathan M. Adams, Jason M. Hall-Spencer
School of Biological and Marine Sciences
No abstract provided.
High‐Energy Surf Zone Currents And Headland Rips At A Geologically Constrained Mesotidal Beach, Arthur Mouragues, Philippe Bonneton, Bruno Castelle, Vincent Marieu, Mccarroll R Jak, I Rodriguez‐Padilla, Tim Scott, Damien Sous
High‐Energy Surf Zone Currents And Headland Rips At A Geologically Constrained Mesotidal Beach, Arthur Mouragues, Philippe Bonneton, Bruno Castelle, Vincent Marieu, Mccarroll R Jak, I Rodriguez‐Padilla, Tim Scott, Damien Sous
School of Biological and Marine Sciences
No abstract provided.
Seasonal Variability Of Eddy Kinetic Energy In The Central Indian Ocean: Polygon-67 Revised, Georgy I. Shapiro, José María Gonzalez-Ondina
Seasonal Variability Of Eddy Kinetic Energy In The Central Indian Ocean: Polygon-67 Revised, Georgy I. Shapiro, José María Gonzalez-Ondina
School of Biological and Marine Sciences
No abstract provided.
Seasonal Variability Of Eddy Kinetic Energy In The Central Indian Ocean: Polygon-67, Gi Shapiro, Jm Gonzalez-Ondina
Seasonal Variability Of Eddy Kinetic Energy In The Central Indian Ocean: Polygon-67, Gi Shapiro, Jm Gonzalez-Ondina
School of Biological and Marine Sciences
Цель. Основной целью данного исследования является анализ сезонной изменчивости мезомасштабной вихревой активности в тропической зоне северной части Индийского океана. Область исследований совпадает с местом проведения эксперимента «Полигон-67» (P67), где впервые были обнаружены мезомасштабные вихри открытого океана. Методы и результаты. Изменчивость кинетической энергии мезомасштабных вихрей в поверхностном слое океана, энстрофия крупномасштабной циркуляции, пространственные и временные структуры поверхностных течений и поверхностных ветров анализируются совместно с использованием 20-летнего временного ряда, содержащего вихреразрешающие массивы реанализа океанских данных, полученных из службы мониторинга морской среды ЕС Copernicus, а также климатических данных о ветре – из управления океанографических и атмосферных исследований США. Быстрые мезомасштабные и медленные крупномасштабные …
Fibroscan-Ast (Fast) Score For The Non-Invasive Identification Of Patients With Non-Alcoholic Steatohepatitis With Significant Activity And Fibrosis: A Prospective Derivation And Global Validation Study, Philip N. Newsome, Magali Sasso, Jonathan J. Deeks, Angelo Paredes, Jérôme Boursier, Wah Kheong Chan, Yusuf Yilmaz, Sébastien Czernichow, Ming Hua Zheng, Vincent Wai Sun Wong, Michael Allison, Emmanuel Tsochatzis, Quentin M. Anstee, David A. Sheridan, Peter J. Eddowes, Indra N. Guha, Jeremy F. Cobbold, Valérie Paradis, Pierre Bedossa, Véronique Miette, Céline Fournier-Poizat, Laurent Sandrin, Stephen A. Harrison
Fibroscan-Ast (Fast) Score For The Non-Invasive Identification Of Patients With Non-Alcoholic Steatohepatitis With Significant Activity And Fibrosis: A Prospective Derivation And Global Validation Study, Philip N. Newsome, Magali Sasso, Jonathan J. Deeks, Angelo Paredes, Jérôme Boursier, Wah Kheong Chan, Yusuf Yilmaz, Sébastien Czernichow, Ming Hua Zheng, Vincent Wai Sun Wong, Michael Allison, Emmanuel Tsochatzis, Quentin M. Anstee, David A. Sheridan, Peter J. Eddowes, Indra N. Guha, Jeremy F. Cobbold, Valérie Paradis, Pierre Bedossa, Véronique Miette, Céline Fournier-Poizat, Laurent Sandrin, Stephen A. Harrison
Peninsula Medical School
No abstract provided.
Constitutive Activation Of The Egfr–Stat1 Axis Increases Proliferation Of Meningioma Tumor Cells, Sara Ferluga, Daniele Baiz, David A. Hilton, Claire L. Adams, Emanuela Ercolano, Jemma Dunn, Kayleigh Bassiri, Kathreena M. Kurian, Clemens O. Hanemann
Constitutive Activation Of The Egfr–Stat1 Axis Increases Proliferation Of Meningioma Tumor Cells, Sara Ferluga, Daniele Baiz, David A. Hilton, Claire L. Adams, Emanuela Ercolano, Jemma Dunn, Kayleigh Bassiri, Kathreena M. Kurian, Clemens O. Hanemann
Peninsula Medical School
Abstract Background Meningiomas are the most frequent primary brain tumors of the central nervous system. The standard of treatment is surgery and radiotherapy, but effective pharmacological options are not available yet. The well-characterized genetic background stratifies these tumors in several subgroups, thus increasing diversification. We identified epidermal growth factor receptor–signal transducer and activator of transcription 1 (EGFR–STAT1) overexpression and activation as a common identifier of these tumors. Methods We analyzed STAT1 overexpression and phosphorylation in 131 meningiomas of different grades and locations by utilizing several techniques, including Western blots, qPCR, and immunocytochemistry. We also silenced and overexpressed wild-type and mutant …
The Changing Face Of Neurosurgery For The Older Person, Ellie Edlmann, Peter C. Whitfield
The Changing Face Of Neurosurgery For The Older Person, Ellie Edlmann, Peter C. Whitfield
Peninsula Medical School
No abstract provided.
Contrasting Impact Of Androgens On Male And Female Adiposity, Fat Distribution And Insulin Resistance In Childhood And Adolescence (Earlybird 75), Jade Chynoweth, Joanne Hosking, Alison Jeffery, Jonathan Pinkney
Contrasting Impact Of Androgens On Male And Female Adiposity, Fat Distribution And Insulin Resistance In Childhood And Adolescence (Earlybird 75), Jade Chynoweth, Joanne Hosking, Alison Jeffery, Jonathan Pinkney
Peninsula Medical School
Objectives: To investigate associations between androgens (testosterone, dehydroepiandrosterone sulphate [DHEAS] and androstenedione), adiposity, fat distribution and insulin resistance (IR) during childhood and adolescence. Methods: Three hundred and seven children (170 [55.4%] boys; 137 [44.6%] girls)recruited at age 5 and studied annually until age 16: androgens (liquid chromatography tandem-mass spectrometry), anthropometry, body composition (dual-energy x-ray absorptiometry) and IR (homeostasis model assessment). Results: Early adiposity was associated with earlier detection of androstenedione in both sexes, and DHEAS in boys. At puberty, higher androgen levels were associated with favourable metabolic changes in boys, but adverse metabolic effects in girls. In boys, higher free …
Offshore Conversion Of Wind Power To Gaseous Fuels: Feasibility Study In A Depleted Gas Field, P. D. O'Kelly-Lynch, P. D. Gallagher, A. G.L. Borthwick, E. J. Mckeogh, P. G. Leahy
Offshore Conversion Of Wind Power To Gaseous Fuels: Feasibility Study In A Depleted Gas Field, P. D. O'Kelly-Lynch, P. D. Gallagher, A. G.L. Borthwick, E. J. Mckeogh, P. G. Leahy
School of Engineering, Computing and Mathematics
A proof-of-concept study is presented of a Power-to-Gas system that is located fully offshore. This paper analyses how such a system would perform if based at the depleted Kinsale Gas Field in the Celtic Sea Basin off the south coast of Ireland. An offshore wind farm is proposed as the power source for the system. Several conversion technologies are examined in detail in terms of resource efficiency, technological maturity, and platform area footprint, the aim being to ascertain their overall applicability to an offshore Power-to-Gas system. The technologies include proton exchange membrane electrolysers for electrolysis of water to release H2. …
The Role Of Natural Fe(Ii)-Bearing Minerals In Chemoautotrophic Chromium (Vi) Bio-Reduction In Groundwater, Jianping Lu, Baogang Zhang, Chao He, Alistair G.L. Borthwick
The Role Of Natural Fe(Ii)-Bearing Minerals In Chemoautotrophic Chromium (Vi) Bio-Reduction In Groundwater, Jianping Lu, Baogang Zhang, Chao He, Alistair G.L. Borthwick
School of Engineering, Computing and Mathematics
No abstract provided.
Sale-Based Estimation Of Pharmaceutical Concentrations And Associated Environmental Risk In The Japanese Wastewater System, Kai He, Alistair G. Borthwick, Yingchao Lin, Yuening Li, Jie Fu, Yongjie Wong, Wen Liu
Sale-Based Estimation Of Pharmaceutical Concentrations And Associated Environmental Risk In The Japanese Wastewater System, Kai He, Alistair G. Borthwick, Yingchao Lin, Yuening Li, Jie Fu, Yongjie Wong, Wen Liu
School of Engineering, Computing and Mathematics
No abstract provided.
Causes And Consequences Of Liana Infestation In Southern Amazonia, Simone Matias Reis, Beatriz Schwantes Marimon, Paulo S. Morandi, Fernando Elias, A Esquivel‐Muelbert, Beatriz Schwantes Marimon, Sophie Fauset, Ea Oliveira, Gmf Heijden, David Galbraith, Ted R. Feldpausch, Oliver L. Phillips
Causes And Consequences Of Liana Infestation In Southern Amazonia, Simone Matias Reis, Beatriz Schwantes Marimon, Paulo S. Morandi, Fernando Elias, A Esquivel‐Muelbert, Beatriz Schwantes Marimon, Sophie Fauset, Ea Oliveira, Gmf Heijden, David Galbraith, Ted R. Feldpausch, Oliver L. Phillips
School of Geography, Earth and Environmental Sciences
No abstract provided.
Changes In Fish Communities Due To Benthic Habitat Shifts Under Ocean Acidification Conditions, Carlo Cattano, Sylvain Agostini, Ben P. Harvey, Shigeki Wada, Federico Quattrocchi, Gabriele Turco, Kazuo Inaba, Jason M. Hall-Spencer, Marco Milazzo
Changes In Fish Communities Due To Benthic Habitat Shifts Under Ocean Acidification Conditions, Carlo Cattano, Sylvain Agostini, Ben P. Harvey, Shigeki Wada, Federico Quattrocchi, Gabriele Turco, Kazuo Inaba, Jason M. Hall-Spencer, Marco Milazzo
School of Biological and Marine Sciences
No abstract provided.
A Robust Blood-Based Signature Of Cerebrospinal Fluid Aβ42 Status, Chima S. Eke, Fatemah Sakr, E. Jammeh, Peng Zhao, E. Ifeachor
A Robust Blood-Based Signature Of Cerebrospinal Fluid Aβ42 Status, Chima S. Eke, Fatemah Sakr, E. Jammeh, Peng Zhao, E. Ifeachor
School of Engineering, Computing and Mathematics
No abstract provided.
Ensuring That Covid-19 Research Is Inclusive - Guidance From The Nihr Include Project, Miles D. Witham, Eleanor Anderson, Camille B. Carroll, Paul M. Dark, Kim Down, Alistair S. Hall, Joanna Knee, Eamonn R. Maher, Rebecca H. Maier, Gail A. Mountain, Gary Nestor, Jt O’Brien, Laurie Oliva, James Wason, Lynn Rochester
Ensuring That Covid-19 Research Is Inclusive - Guidance From The Nihr Include Project, Miles D. Witham, Eleanor Anderson, Camille B. Carroll, Paul M. Dark, Kim Down, Alistair S. Hall, Joanna Knee, Eamonn R. Maher, Rebecca H. Maier, Gail A. Mountain, Gary Nestor, Jt O’Brien, Laurie Oliva, James Wason, Lynn Rochester
Peninsula Medical School
No abstract provided.
Dynamic Expression Of Slit1-3 And Robo1-2 In The Mouse Peripheral Nervous System After Injury, Bing Chen, Lauren Carr, Xin-Peng Dun
Dynamic Expression Of Slit1-3 And Robo1-2 In The Mouse Peripheral Nervous System After Injury, Bing Chen, Lauren Carr, Xin-Peng Dun
Peninsula Medical School
The Slit family of axon guidance cues act as repulsive molecules for precise axon pathfinding and neuronal migration during nervous system development through interactions with specific Robo receptors. Although we previously reported that Slit1-3 and their receptors Robo1 and Robo2 are highly expressed in the adult mouse peripheral nervous system, how this expression changes after injury has not been well studied. Herein, we constructed a peripheral nerve injury mouse model by transecting the right sciatic nerve. At 14 days after injury, quantitative real-time polymerase chain reaction was used to detect mRNA expression of Slit1-3 and Robo1-2 in L4-5 spinal cord …
Coronavirus (Covid-19) In The Uk: A Personality-Based Perspective On Concerns And Intention To Self-Isolate, Alison M. Bacon, Philip J. Corr
Coronavirus (Covid-19) In The Uk: A Personality-Based Perspective On Concerns And Intention To Self-Isolate, Alison M. Bacon, Philip J. Corr
School of Psychology
No abstract provided.
Juvenile Bonefish (Albula Vulpes) Show A Preference To Shoal With Mojarra (Eucinostomus Spp.) In The Presence Of Conspecifics And Another Gregarious Co-Occurring Species, Petra Szekeres, Christopher R. Haak, Alexander D.M. Wilson, Andy J. Danylchuk, Jacob W. Brownscombe, Aaron D. Shultz, Steven J. Cooke
Juvenile Bonefish (Albula Vulpes) Show A Preference To Shoal With Mojarra (Eucinostomus Spp.) In The Presence Of Conspecifics And Another Gregarious Co-Occurring Species, Petra Szekeres, Christopher R. Haak, Alexander D.M. Wilson, Andy J. Danylchuk, Jacob W. Brownscombe, Aaron D. Shultz, Steven J. Cooke
School of Biological and Marine Sciences
No abstract provided.
Measurement And Modelling Of Deep Sea Sediment Plumes And Implications For Deep Sea Mining, J Spearman, J Taylor, N Crossouard, A Cooper, M Turnbull, A Manning, M Lee, B Murton
Measurement And Modelling Of Deep Sea Sediment Plumes And Implications For Deep Sea Mining, J Spearman, J Taylor, N Crossouard, A Cooper, M Turnbull, A Manning, M Lee, B Murton
School of Biological and Marine Sciences
No abstract provided.