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The Oceanic Biogeochemistry Of Nickel And Its Isotopes: New Data From The South Atlantic And The Southern Ocean Biogeochemical Divide, Corey Archer, Derek Vance, Angela Milne, Maeve C. Lohan Apr 2020

The Oceanic Biogeochemistry Of Nickel And Its Isotopes: New Data From The South Atlantic And The Southern Ocean Biogeochemical Divide, Corey Archer, Derek Vance, Angela Milne, Maeve C. Lohan

School of Geography, Earth and Environmental Sciences

No abstract provided.


Design Catalogue For Eco-Engineering Of Coastal Artificial Structures: A Multifunctional Approach For Stakeholders And End-Users, Kathryn A. O’Shaughnessy, Stephen J. Hawkins, Ally J. Evans, Mick E. Hanley, Paul Lunt, Richard C. Thompson, Robert A. Francis, Simon P.G. Hoggart, Pippa J. Moore, Gregorio Iglesias, David Simmonds, James Ducker, Louise B. Firth Apr 2020

Design Catalogue For Eco-Engineering Of Coastal Artificial Structures: A Multifunctional Approach For Stakeholders And End-Users, Kathryn A. O’Shaughnessy, Stephen J. Hawkins, Ally J. Evans, Mick E. Hanley, Paul Lunt, Richard C. Thompson, Robert A. Francis, Simon P.G. Hoggart, Pippa J. Moore, Gregorio Iglesias, David Simmonds, James Ducker, Louise B. Firth

School of Biological and Marine Sciences

Coastal urbanisation, energy extraction, food production, shipping and transportation have led to the global proliferation of artificial structures within the coastal and marine environments (sensu “ocean sprawl”), with subsequent loss of natural habitats and biodiversity. To mitigate and compensate impacts of ocean sprawl, the practice of eco-engineering of artificial structures has been developed over the past decade. Eco-engineering aims to create sustainable ecosystems that integrate human society with the natural environment for the benefit of both. The science of eco-engineering has grown markedly, yet synthesis of research into a user-friendly and practitioner-focused format is lacking. Feedback from stakeholders has repeatedly …


Effectiveness Of Nurse-Coordinated, Person-Centered Comprehensive Assessment On Improving Quality Of Life Of Community-Dwelling, Frail Older People: A Systematic Review Protocol, Helen Lyndon, Frazer Underwood, Jos M. Latour, Jonathan Marsden, Anne Brown, Bridie Kent Apr 2020

Effectiveness Of Nurse-Coordinated, Person-Centered Comprehensive Assessment On Improving Quality Of Life Of Community-Dwelling, Frail Older People: A Systematic Review Protocol, Helen Lyndon, Frazer Underwood, Jos M. Latour, Jonathan Marsden, Anne Brown, Bridie Kent

School of Nursing and Midwifery

Objective: The objective of this systematic review is to determine the effectiveness of nurse-coordinated, person-centered comprehensive assessment on improving quality of life of community-dwelling, frail older people. Introduction: There is a growing need to meet the challenges of the increasingly frail and older population, and to provide proactive, holistic care close to home. A standardized assessment and care planning intervention could be implemented in primary care, which could be delivered by a primary or community healthcare nurse to address these challenges. However, it is not yet clear if an assessment and care planning intervention will improve outcomes for patients, such …


Lifeform Indicators Reveal Large-Scale Shifts In Plankton Across The North-West European Shelf, Jacob Bedford, Clare Ostle, David G. Johns, Angus Atkinson, Mike Best, Eileen Bresnan, Margarita Machairopoulou, Carolyn A. Graves, Michelle Devlin, Alex Milligan, Sophie Pitois, Adam Mellor, Paul Tett, Abigail Mcquatters-Gollop Apr 2020

Lifeform Indicators Reveal Large-Scale Shifts In Plankton Across The North-West European Shelf, Jacob Bedford, Clare Ostle, David G. Johns, Angus Atkinson, Mike Best, Eileen Bresnan, Margarita Machairopoulou, Carolyn A. Graves, Michelle Devlin, Alex Milligan, Sophie Pitois, Adam Mellor, Paul Tett, Abigail Mcquatters-Gollop

School of Biological and Marine Sciences

No abstract provided.


Mothering In Hindsight: Troubling Time(S), M Lavelle Mar 2020

Mothering In Hindsight: Troubling Time(S), M Lavelle

Plymouth Institute of Education

This article draws on a small-scale study that explored the (re)configuring, (re)turning and (re)working of the experiences of mothering as seen from a position of looking back in hindsight. Temporality is implicated in several ways within this paper, deeply entwined and constantly shifting. Researching past events, experiences and emotions that appear in a location not of the present is problematic, especially when time is conceptualised chronologically. Making sense of past experiences of mothering in the present exposed parenting as not necessarily something that can be detached from the past or as an experience that lies in the past, but rather …


Vesiculation Of Red Blood Cells In The Blood Bank: A Multi-Omics Approach Towards Identification Of Causes And Consequences, Leal Jk Freitas, Edwin Lasonder, Vikram Sharma, Jürgen Schiller, Giuseppina Fanelli, Sara Rinalducci, Roland Brock, Giel Bosman Mar 2020

Vesiculation Of Red Blood Cells In The Blood Bank: A Multi-Omics Approach Towards Identification Of Causes And Consequences, Leal Jk Freitas, Edwin Lasonder, Vikram Sharma, Jürgen Schiller, Giuseppina Fanelli, Sara Rinalducci, Roland Brock, Giel Bosman

School of Biomedical Sciences

Microvesicle generation is an integral part of the aging process of red blood cells in vivo and in vitro. Extensive vesiculation impairs function and survival of red blood cells after transfusion, and microvesicles contribute to transfusion reactions. The triggers and mechanisms of microvesicle generation are largely unknown. In this study, we combined morphological, immunochemical, proteomic, lipidomic, and metabolomic analyses to obtain an integrated understanding of the mechanisms underlying microvesicle generation during the storage of red blood cell concentrates. Our data indicate that changes in membrane organization, triggered by altered protein conformation, constitute the main mechanism of vesiculation, and precede changes …


Speech Fundamental Period Estimation Using A Neural Network, I Howard Mar 2020

Speech Fundamental Period Estimation Using A Neural Network, I Howard

School of Engineering, Computing and Mathematics

No abstract provided.


Artificial And Natural Radionuclides In Cryoconite As Tracers Of Supraglacial Dynamics: Insights From The Morteratsch Glacier (Swiss Alps), G Baccolo, M Nastasi, C Clason, B Di Mauro, Et Al Mar 2020

Artificial And Natural Radionuclides In Cryoconite As Tracers Of Supraglacial Dynamics: Insights From The Morteratsch Glacier (Swiss Alps), G Baccolo, M Nastasi, C Clason, B Di Mauro, Et Al

School of Geography, Earth and Environmental Sciences

Cryoconite, a sediment found on the surface of glaciers, is known for its ability to accumulate radionuclides. New data on cryoconite from the Morteratsch glacier (Switzerland) are presented to shed light on the mechanisms that control the distribution of radioactivity in cryoconite. Among the radionuclides detected in our samples, we have identified 108mAg, an artificial species which has never been observed in terrestrial environments before. This finding supports that cryoconite has an extraordinary ability to accumulate radioactivity. Our results also show that the radioactivity of cryoconite from a single glacier is far from uniform. Both the absolute amount of radioactivity …


A Scoping Review Protocol To Map Empirical Evidence That Illuminates The Dark Side Of Occupations Among Adults, R Twinley, L Boland, L Bunn, G Letherby Mar 2020

A Scoping Review Protocol To Map Empirical Evidence That Illuminates The Dark Side Of Occupations Among Adults, R Twinley, L Boland, L Bunn, G Letherby

School of Health Professions

The objective of this review is to explore existing literature to identify, map, and synthesise past accounts of occupations that could be considered as constituting the dark side of occupation and which could, consequently, be identified and discussed as such. Presenting findings through use of a synthesis matrix, and formulating a descriptive account of the types of occupations (including their form, function, meaning, and contribution to identity and becoming) that constitute the dark side of occupation, is anticipated to assist with prioritising future collaborative research endeavours, as part of an intended programme of research. Specifically, the review questions are: What …


Genetic Networks In Parkinson's And Alzheimer's Disease, Jack Kelly, Rana Moyeed, Camille Carroll, Shouqing Luo, Xinzhong Li Mar 2020

Genetic Networks In Parkinson's And Alzheimer's Disease, Jack Kelly, Rana Moyeed, Camille Carroll, Shouqing Luo, Xinzhong Li

More Faculty of Health Research

Parkinson's disease (PD) and Alzheimer's disease (AD) are the most common neurodegenerative diseases and there is increasing evidence that they share common physiological and pathological links. Here we have conducted the largest network analysis of PD and AD based on their gene expressions in blood to date. We identified modules that were not preserved between disease and healthy control (HC) networks, and important hub genes and transcription factors (TFs) in these modules. We highlighted that the PD module not preserved in HCs was associated with insulin resistance, and HDAC6 was identified as a hub gene in this module which may …


Teaching Post-Secondary Students In Ecology And Evolution: Strategies For Early-Career Researchers, G Raby, Jm Chapman, Bruijn R De, Ej Eliason, Ck Elvidge, Ct Hasler, Cl Madliger, Ea Nyboer, Aj Reid, Dg Roche, T Rytwinski, Td Ward, Adm Wilson, Sj Cooke Mar 2020

Teaching Post-Secondary Students In Ecology And Evolution: Strategies For Early-Career Researchers, G Raby, Jm Chapman, Bruijn R De, Ej Eliason, Ck Elvidge, Ct Hasler, Cl Madliger, Ea Nyboer, Aj Reid, Dg Roche, T Rytwinski, Td Ward, Adm Wilson, Sj Cooke

School of Biological and Marine Sciences

Teaching can be a rewarding, yet challenging, experience for early career researchers (ECRs) in fields like ecology and evolution. Much of this challenge arises from the reality that ECRs in ecology and evolution typically receive little, if any, pedagogical training or advice on how to balance teaching, research (which can include extended field work), and other demands on their time. Here, we aim to provide accessible, pragmatic advice for ECRs in ecology and evolution who are given the opportunity to teach (as instructor of record). The advice is based on the authors’ collective experiences teaching in ecology and evolution as …


Microplastics In Sea Ice And Seawater Beneath Ice Floes From The Arctic Ocean, La Daana K. Kanhai, Katarina Gardfeldt, Thomas Krumpen, Richard C. Thompson, Ian O’Connor Mar 2020

Microplastics In Sea Ice And Seawater Beneath Ice Floes From The Arctic Ocean, La Daana K. Kanhai, Katarina Gardfeldt, Thomas Krumpen, Richard C. Thompson, Ian O’Connor

School of Biological and Marine Sciences

No abstract provided.


Responses Of Intertidal Bacterial Biofilm Communities To Increasing Pco2, Dorsaf Kerfahi, Ben P. Harvey, Sylvain Agostini, Koetsu Kon, Ruiping Huang, Jonathan M. Adams, Jason M. Hall-Spencer Mar 2020

Responses Of Intertidal Bacterial Biofilm Communities To Increasing Pco2, Dorsaf Kerfahi, Ben P. Harvey, Sylvain Agostini, Koetsu Kon, Ruiping Huang, Jonathan M. Adams, Jason M. Hall-Spencer

School of Biological and Marine Sciences

No abstract provided.


Microfiber Release To Water, Via Laundering, And To Air, Via Everyday Use: A Comparison Between Polyester Clothing With Differing Textile Parameters, Falco F De, Mariacristina Cocca, Maurizio Avella, Richard C. Thompson Mar 2020

Microfiber Release To Water, Via Laundering, And To Air, Via Everyday Use: A Comparison Between Polyester Clothing With Differing Textile Parameters, Falco F De, Mariacristina Cocca, Maurizio Avella, Richard C. Thompson

School of Biological and Marine Sciences

No abstract provided.


Nutrient Extraction Lowers Postprandial Glucose Response Of Fruit In Adults With Obesity As Well As Healthy Weight Adults, Rabab Alkutbe, Kathy Redfern, Michael Jarvis, Gail Rees Mar 2020

Nutrient Extraction Lowers Postprandial Glucose Response Of Fruit In Adults With Obesity As Well As Healthy Weight Adults, Rabab Alkutbe, Kathy Redfern, Michael Jarvis, Gail Rees

School of Biomedical Sciences

Fruit consumption is recommended as part of a healthy diet. However, consumption of fruit in the form of juice is positively associated with type 2 diabetes risk, possibly due to resulting hyperglycemia. In a recent study, fruit juice prepared by nutrient extraction, a process that retains the fiber component, was shown to elicit a favorable glycemic index (GI), compared to eating the fruit whole, in healthy weight adults. The current study expanded on this to include individuals with obesity, and assessed whether the nutrient extraction of seeded fruits reduced GI in a higher disease risk group. Nutrient extraction was shown …


Tadpole Vr: Virtual Reality Visualization Of A Simulated Tadpole Spinal Cord, Marius N. Varga, Robert Merrison-Hort, Paul Watson, Roman Borisyuk, Dan Livingstone Mar 2020

Tadpole Vr: Virtual Reality Visualization Of A Simulated Tadpole Spinal Cord, Marius N. Varga, Robert Merrison-Hort, Paul Watson, Roman Borisyuk, Dan Livingstone

School of Art, Design and Architecture

Recent advances in “developmental” approach (combining experimental study with computational modelling) of neural networks produces increasingly large data sets, in both complexity and size. This poses a significant challenge in analyzing, visualizing and understanding not only the spatial structure but also the behavior of such networks. This paper describes a Virtual Reality application for visualization of two biologically accurate computational models that model the anatomical structure of a neural network comprised of 1,500 neurons and over 80,000 connections. The visualization enables a user to observe the complex spatio-temporal interplay between seven unique types of neurons culminating in an observable swimming …


A Dimensional Summation Account Of Polymorphous Category Learning, Andy J. Wills, Lyn Ellett, Fraser Milton, Gareth Croft, Tom Beesley Mar 2020

A Dimensional Summation Account Of Polymorphous Category Learning, Andy J. Wills, Lyn Ellett, Fraser Milton, Gareth Croft, Tom Beesley

School of Psychology

No abstract provided.


Outcome Of Root Canal Treatments Using A New Calcium Silicate Root Canal Sealer: A Non-Randomized Clinical Trial, A Zavattini, A Knight, F Foschi, F Mannocci Mar 2020

Outcome Of Root Canal Treatments Using A New Calcium Silicate Root Canal Sealer: A Non-Randomized Clinical Trial, A Zavattini, A Knight, F Foschi, F Mannocci

Peninsula Dental School

Background: The aim of this study was to compare the success rate of root canal treatments undertaken using a calcium silicate root canal sealer in combination with a single cone with non-calcium silicate cement and warm vertical condensation. Methods: 150 necrotic or pulpitic teeth were treated. (REC: 08/H0804/79). Following standardized root canal chemo-debridement. The canals were obturated using warm vertical condensation of gutta-percha and epoxy-based sealer (AH plus) or a calcium silicate sealer (BioRootTM RCS) with a single cone technique. Follow-up assessment was conducted at 12 months using Cone Beam Computed Tomography (CBCT). Results: At 1-year recall, 104 teeth were …


A Novel Lactic Acid Bacteria Mixture: Macrophage-Targeted Prophylactic Intervention In Colorectal Cancer Management, Petra Hradicka, Jane Beal, Monika Kassayova, Andrew Foey, Vlasta Demeckova Mar 2020

A Novel Lactic Acid Bacteria Mixture: Macrophage-Targeted Prophylactic Intervention In Colorectal Cancer Management, Petra Hradicka, Jane Beal, Monika Kassayova, Andrew Foey, Vlasta Demeckova

School of Biomedical Sciences

Colorectal cancer (CRC) is one of the most common forms of cancer. Its onset from chronic inflammation is widely accepted. Moreover, dysbiosis plays an undeniable role, thus the use of probiotics in CRC has been suggested. They exhibit both anti- and pro-inflammatory properties and restore balance in the microbiota. The aim of this study was to investigate the immunomodulatory properties of six lactobacilli with probiotic features in an in vitro model of macrophage-like cells and to test these pooled probiotics for their anti-tumour properties in a chemically induced CRC model using Wistar male rats. Upon co-culture of M1- and M2-like …


Nad (P) Transhydrogenase Has Vital Non‐Mitochondrial Functions In Malaria Parasite Transmission, Sadia Saeed, Annie Z. Tremp, Vikram Sharma, Edwin Lasonder, Johannes T. Dessens Mar 2020

Nad (P) Transhydrogenase Has Vital Non‐Mitochondrial Functions In Malaria Parasite Transmission, Sadia Saeed, Annie Z. Tremp, Vikram Sharma, Edwin Lasonder, Johannes T. Dessens

School of Biomedical Sciences

No abstract provided.


Purification And Characterization Of Nisin P Produced By A Strain Of Streptococcus Gallolyticus, Abdu Aldarhami, Arif Felek, Vikram Sharma, Mathew Upton Mar 2020

Purification And Characterization Of Nisin P Produced By A Strain Of Streptococcus Gallolyticus, Abdu Aldarhami, Arif Felek, Vikram Sharma, Mathew Upton

School of Biomedical Sciences

No abstract provided.


Fire As A Selective Agent For Both Serotiny And Nonserotiny Over Space And Time, Byron B. Lamont, Juli G. Pausas, Tianhua He, Ed T.F. Witkowski, Mick E. Hanley Mar 2020

Fire As A Selective Agent For Both Serotiny And Nonserotiny Over Space And Time, Byron B. Lamont, Juli G. Pausas, Tianhua He, Ed T.F. Witkowski, Mick E. Hanley

School of Biological and Marine Sciences

No abstract provided.


Development And Testing Scenarios For Implementing Land Use And Land Cover Changes During The Holocene In Earth System Model Experiments, Sp Harrison, M-J Gaillard, Bd Stocker, M Vander Linden, Et Al Mar 2020

Development And Testing Scenarios For Implementing Land Use And Land Cover Changes During The Holocene In Earth System Model Experiments, Sp Harrison, M-J Gaillard, Bd Stocker, M Vander Linden, Et Al

School of Geography, Earth and Environmental Sciences

Abstract. Anthropogenic changes in land use and land cover (LULC) during the pre-industrial Holocene could have affected regional and global climate. Existing scenarios of LULC changes during the Holocene are based on relatively simple assumptions and highly uncertain estimates of population changes through time. Archaeological and palaeoenvironmental reconstructions have the potential to refine these assumptions and estimates. The Past Global Changes (PAGES) LandCover6k initiative is working towards improved reconstructions of LULC globally. In this paper, we document the types of archaeological data that are being collated and how they will be used to improve LULC reconstructions. Given the large methodological …


What Should We Call The Levant Mole? Unravelling The Systematics And Demography Of Talpa Levantis Thomas, 1906 Sensu Lato (Mammalia: Talpidae), S Demirtas, M Silsupur, Jeremy B. Searle, David Bilton, I Gunduz Mar 2020

What Should We Call The Levant Mole? Unravelling The Systematics And Demography Of Talpa Levantis Thomas, 1906 Sensu Lato (Mammalia: Talpidae), S Demirtas, M Silsupur, Jeremy B. Searle, David Bilton, I Gunduz

School of Biological and Marine Sciences

No abstract provided.


Predictive Coding In Auditory Perception: Challenges And Unresolved Questions, Sl Denham, I Winkler Mar 2020

Predictive Coding In Auditory Perception: Challenges And Unresolved Questions, Sl Denham, I Winkler

School of Psychology

Predictive coding is arguably the currently dominant theoretical framework for the study of perception. It has been employed to explain important auditory perceptual phenomena, and it has inspired theoretical, experimental and computational modelling efforts aimed at describing how the auditory system parses the complex sound input into meaningful units (auditory scene analysis). These efforts have uncovered some vital questions, addressing which could help to further specify predictive coding and clarify some of its basic assumptions. The goal of the current review is to motivate these questions and show how unresolved issues in explaining some auditory phenomena lead to general questions …


Microplastics And Seafood: Lower Trophic Organisms At Highest Risk Of Contamination, Chris Walkinshaw, Penelope K. Lindeque, Richard Thompson, Trevor Tolhurst, Matthew Cole Mar 2020

Microplastics And Seafood: Lower Trophic Organisms At Highest Risk Of Contamination, Chris Walkinshaw, Penelope K. Lindeque, Richard Thompson, Trevor Tolhurst, Matthew Cole

School of Biological and Marine Sciences

No abstract provided.


Do Differences In Developmental Mode Shape The Potential For Local Adaptation?, L. L. Jupe, D. T. Bilton, A. M. Knights Mar 2020

Do Differences In Developmental Mode Shape The Potential For Local Adaptation?, L. L. Jupe, D. T. Bilton, A. M. Knights

School of Biological and Marine Sciences

Future climate change is leading to the redistribution of life on Earth as species struggle to cope with rising temperatures. Local adaptation allows species to become locally optimized and persist despite environmental selection, but the extent to which this occurs in nature may be limited by dispersal and gene flow. Congeneric marine gastropod species (Littorina littorea and L. saxatilis) with markedly different developmental modes were collected from across a latitudinal thermal gradient to explore the prevalence of local adaptation to temperature. The acute response of metabolic rate (using oxygen consumption as a proxy) to up-ramping and down-ramping temperature regimes between …


Toxicities Of Copper Oxide Nanomaterial And Copper Sulphate In Early Life Stage Zebrafish: Effects Of Ph And Intermittent Pulse Exposure, David Boyle, Nathaniel J. Clark, Richard D. Handy Mar 2020

Toxicities Of Copper Oxide Nanomaterial And Copper Sulphate In Early Life Stage Zebrafish: Effects Of Ph And Intermittent Pulse Exposure, David Boyle, Nathaniel J. Clark, Richard D. Handy

School of Health Professions

No abstract provided.


A Comparison Of Ground-Based Methods For Obtaining Large-Scale, High-Resolution Data On The Spring Leaf Phenology Of Temperate Tree Species, Am Smith, Pm Ramsay Mar 2020

A Comparison Of Ground-Based Methods For Obtaining Large-Scale, High-Resolution Data On The Spring Leaf Phenology Of Temperate Tree Species, Am Smith, Pm Ramsay

School of Biological and Marine Sciences

Phenological variation in spring leafing between and within species can determine plant responses to warmer winter and spring temperatures in the short term. Methods are needed for monitoring canopy development that can be replicated on a large-scale, while retaining fine-scale resolution at the level of individual trees. Citizen science has the potential to provide this, but a range of approaches exist in terms of the phenophase recorded (e.g. budburst or leaf expansion), how the phenophase is characterised (first events or intensity monitoring) and the portion of tree crown assessed and observation frequency. A comparison of spring budburst and leaf expansion …


Citizen Science In The Marine Environment: Estimating Common Dolphin Densities In The North-East Atlantic, James R. Robbins, Lucy Babey, Clare B. Embling Feb 2020

Citizen Science In The Marine Environment: Estimating Common Dolphin Densities In The North-East Atlantic, James R. Robbins, Lucy Babey, Clare B. Embling

School of Biological and Marine Sciences

Background Citizen science is increasingly popular and has the potential to collect extensive datasets at lower costs than traditional surveys conducted by professional scientists. Ferries have been used to collect data on cetacean populations for decades, providing long-term time series for monitoring of cetacean populations. One cetacean species of concern is the common dolphin, which has been found stranded around the north-east Atlantic in recent years, with high numbers on French coasts being attributed to fisheries bycatch. We estimate common dolphin densities in the north-east Atlantic and investigate the ability of citizen science data to identify changes in marine mammal …