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Cross-Sectional Age Differences In 24 Character Strengths: Five Meta-Analyses From Early Adolescence To Late Adulthood, Sonja Heintz, Willibald Ruch Feb 2021

Cross-Sectional Age Differences In 24 Character Strengths: Five Meta-Analyses From Early Adolescence To Late Adulthood, Sonja Heintz, Willibald Ruch

School of Psychology

No abstract provided.


Response Of Biological Productivity To North Atlantic Marine Front Migration During The Holocene, David J. Harning, Anne E. Jennings, D Köseoğlu, Simon T. Belt, Áslaug Geirsdóttir, Julio Sepúlveda Feb 2021

Response Of Biological Productivity To North Atlantic Marine Front Migration During The Holocene, David J. Harning, Anne E. Jennings, D Köseoğlu, Simon T. Belt, Áslaug Geirsdóttir, Julio Sepúlveda

School of Geography, Earth and Environmental Sciences

Abstract. Marine fronts delineate the boundary between distinct water masses and, through the advection of nutrients, are important facilitators of regional productivity and biodiversity. As the modern climate continues to change, the migration of frontal zones is evident, but a lack of information about their status prior to instrumental records hinders future projections. Here, we combine data from lipid biomarkers (archaeal isoprenoid glycerol dibiphytanyl glycerol tetraethers and algal highly branched isoprenoids) with planktic and benthic foraminifera assemblages to detail the biological response of the marine Arctic and polar front migrations on the North Iceland Shelf (NIS) over the last 8 …


The Sewage Sludge Biochar And Its Composts Influence The Phosphate Sorption In An Alkaline–Calcareous Soil, Ra Rehman, Mf Qayyum, G Haider, K Schofield, Et Al Feb 2021

The Sewage Sludge Biochar And Its Composts Influence The Phosphate Sorption In An Alkaline–Calcareous Soil, Ra Rehman, Mf Qayyum, G Haider, K Schofield, Et Al

School of Geography, Earth and Environmental Sciences

This study evaluates the potential of sewage sludge, farm manure, rock phosphate, and their composts or biochar as useful materials for phosphorous (P) recovery. An alkaline–calcareous soil was incubated with different compost-based amendments to discern their impact on the P sorption characteristics. The treatments examined consisted of sewage sludge (SS), SS biochar (SS-BC), or composts of SS with rock phosphate (RP) and farm manure (FM) in different ratios, i.e., (i) control, (ii) SS, (iii) SS-BC, (iv) SS50:FM50, (v) SS75:FM25, (vi) SS25:FM25:RP50, (vii) SS50:FM25:RP25, (viii) SS75:FM0:RP25, and (ix) SS50:FM0:RP50. Prior to incubation for 45 days, the composts and biochar treatments combinations …


Life History And Ecology Of Bluenose Warehou (Hyperoglyphe Antarctica, Centrolophidae) In The Southern Atlantic, James B. Bell, Vladimir Laptikhovsky, David K.A. Barnes, Ramon Benedet, Amelia E. Bridges, J Glass, W Glass, Rodney Green, Simon A. Morley, Simon Robertson, Georgia R. Robson, Harry Stanton, Freja Azzopardi, Clive N. Trueman, Oliver Yates, Martin A. Collins Feb 2021

Life History And Ecology Of Bluenose Warehou (Hyperoglyphe Antarctica, Centrolophidae) In The Southern Atlantic, James B. Bell, Vladimir Laptikhovsky, David K.A. Barnes, Ramon Benedet, Amelia E. Bridges, J Glass, W Glass, Rodney Green, Simon A. Morley, Simon Robertson, Georgia R. Robson, Harry Stanton, Freja Azzopardi, Clive N. Trueman, Oliver Yates, Martin A. Collins

School of Biological and Marine Sciences

Bluenose warehou (Hyperoglyphe antarctica) is a popular commercial fish in Australia and New Zealand, but its biology and ecology are very poorly known in other regions where it is found. We present here the first life history data for this species from the south Atlantic, focusing upon the exclusive economic zone (EEZ) of the United Kingdom Overseas Territory (UKOT) of Tristan da Cunha (TdC). Here, bluenose is known from several seamounts and island margins, typically occurring in waters between 200 and 1,000 m depth and is the target species of trawl and longline fishery operating since 1997. We use a …


Assessment During Intergroup Contests, P. A. Green, M. Briffa, M. A. Cant Feb 2021

Assessment During Intergroup Contests, P. A. Green, M. Briffa, M. A. Cant

School of Biological and Marine Sciences

No abstract provided.


Ervilia Castanea (Mollusca, Bivalvia) Populations Adversely Affected At Co2 Seeps In The North Atlantic, M Martins, Marina Carreiro-Silva, Gm Martins, E Ramos J Barcelos, Fátima Viveiros, Ruben P. Couto, Hugo Parra, João Monteiro, Francesca Gallo, Catarina Silva, Alexandra Teodósio, Katja Guilini, Jason M. Hall-Spencer, Francisco Leitão, Luís Chícharo, Pedro Range Feb 2021

Ervilia Castanea (Mollusca, Bivalvia) Populations Adversely Affected At Co2 Seeps In The North Atlantic, M Martins, Marina Carreiro-Silva, Gm Martins, E Ramos J Barcelos, Fátima Viveiros, Ruben P. Couto, Hugo Parra, João Monteiro, Francesca Gallo, Catarina Silva, Alexandra Teodósio, Katja Guilini, Jason M. Hall-Spencer, Francisco Leitão, Luís Chícharo, Pedro Range

School of Biological and Marine Sciences

No abstract provided.


The Second World Ocean Assessment Volume Ii, J Hall-Spencer Feb 2021

The Second World Ocean Assessment Volume Ii, J Hall-Spencer

School of Biological and Marine Sciences

No abstract provided.


Attention Deficit Hyperactivity Disorder (Adhd) In Adults With Intellectual Disability, Rohit Shankar, Bhathika Perera, Laura Korb, Ken Courtenay Feb 2021

Attention Deficit Hyperactivity Disorder (Adhd) In Adults With Intellectual Disability, Rohit Shankar, Bhathika Perera, Laura Korb, Ken Courtenay

Peninsula Medical School

The field of neurodevelopmental disorders is an exciting one in clinical practice. Peoplewith intellectual disability are more likely to have associated neurodevelopmental disorderssuch as autism and attention hyperactivity disorder (ADHD). The current practice ofdiagnosis and management of ADHD in people with intellectual disability is basedon findings from assessment and treatments in the general population. People withintellectual disability often have additional comorbid disorders that may conceal orexacerbate the signs of ADHD and, for this reason, treatments applicable in the generalpopulation may not always be appropriate in treating a person with intellectual disability.To fill this gap in knowledge and practice, this College …


Do Aquatic Ectotherms Perform Better Under Hypoxia After Warm Acclimation?, Michael Collins, Manuela Truebano, Wilco C.E.P. Verberk, John I. Spicer Feb 2021

Do Aquatic Ectotherms Perform Better Under Hypoxia After Warm Acclimation?, Michael Collins, Manuela Truebano, Wilco C.E.P. Verberk, John I. Spicer

School of Biological and Marine Sciences

ABSTRACTAquatic animals increasingly encounter environmental hypoxia due to climate-related warming and/or eutrophication. Although acute warming typically reduces performance under hypoxia, the ability of organisms to modulate hypoxic performance via thermal acclimation is less understood. Here, we review the literature and ask whether hypoxic performance of aquatic ectotherms improves following warm acclimation. Interpretation of thermal acclimation effects is limited by reliance on data from experiments that are not designed to directly test for beneficial or detrimental effects on hypoxic performance. Most studies have tested hypoxic responses exclusively at test temperatures matching organisms' acclimation temperatures, precluding the possibility of distinguishing between acclimation …


Monitoring Water Quality Changes And Ornamental Fish Behaviour During Commercial Transport, M Vanderzwalmen, J Mcneill, D Delieuvin, S Senes, D Sanchez-Lacalle, C Mullen, I Mclellan, P Carey, D Snellgrove, A Foggo, Me Alexander, Fl Henriquez, Ka Sloman Jan 2021

Monitoring Water Quality Changes And Ornamental Fish Behaviour During Commercial Transport, M Vanderzwalmen, J Mcneill, D Delieuvin, S Senes, D Sanchez-Lacalle, C Mullen, I Mclellan, P Carey, D Snellgrove, A Foggo, Me Alexander, Fl Henriquez, Ka Sloman

School of Biological and Marine Sciences

No abstract provided.


Native Woodland Establishment Improves Soil Hydrological Functioning In Uk Upland Pastoral Catchments, Thomas R. Murphy, Mick E. Hanley, Jon S. Ellis, Paul H. Lunt Jan 2021

Native Woodland Establishment Improves Soil Hydrological Functioning In Uk Upland Pastoral Catchments, Thomas R. Murphy, Mick E. Hanley, Jon S. Ellis, Paul H. Lunt

School of Geography, Earth and Environmental Sciences

No abstract provided.


From Matte Banded To Glossy Black: Structures Underlying Colour Change In The Caudal Lures Of Southern Death Adders (Acanthophis Antarcticus, Reptilia: Elapidae), Jenna M. Crowe-Riddell, Stacey Dix, Ludo Pieterman, James H. Nankivell, Bruno Fonseca Simoes, Matthew Ford, Alastair J. Ludington, Nathan Dunstan, Julian C. Partridge, Kate L. Sanders, Luke Allen Jan 2021

From Matte Banded To Glossy Black: Structures Underlying Colour Change In The Caudal Lures Of Southern Death Adders (Acanthophis Antarcticus, Reptilia: Elapidae), Jenna M. Crowe-Riddell, Stacey Dix, Ludo Pieterman, James H. Nankivell, Bruno Fonseca Simoes, Matthew Ford, Alastair J. Ludington, Nathan Dunstan, Julian C. Partridge, Kate L. Sanders, Luke Allen

School of Biological and Marine Sciences

Many ambush-foraging snakes move their tails to entice prey within striking range ('caudal luring'). During ontogeny, the conspicuous hues of caudal lures change to match the cryptic patterning of the body/head. This coincides with decreased luring behaviour and reflects the trade-off between prey acquisition and camouflage as the snake grows. Australo-Papuan death adders (Acanthophis, Elapidae) are unique in that both juveniles and adults use caudal luring, but ontogenetic colour change has not been investigated. We examined the spectral reflectance, microstructure and pigmentation of caudal skin in wild-sourced and captive bred Acanthopihs antarcticus ranging in body size (snout-vent length 116-674 mm; …


Virtual Capacity Building For International Research Collaborations In Times Of Covid-19 And #Flygskam, I Richter, E Gabe-Thomas, C Maharja, Th Nguyen, Nguyen Q Van, R Praptiwi, S Pahl Jan 2021

Virtual Capacity Building For International Research Collaborations In Times Of Covid-19 And #Flygskam, I Richter, E Gabe-Thomas, C Maharja, Th Nguyen, Nguyen Q Van, R Praptiwi, S Pahl

School of Psychology

In the wake of the current global pandemic, international travel is restricted. This poses substantial challenges for research relationships aiming to build capacity and foster co-creation to achieve the Sustainable Development Goals, where global collaboration and communication is paramount. This is especially challenging when it comes to interactive dialogues that go beyond the typical one-way structure of online learning. Considerations on structural, technical and behavioral levels are needed to not only deal with these challenges but rather to take advantage of the new situation. This commentary outlines the lessons learned from an internationally operating project, co-developed to cope with travel …


Impact Of Influenza Vaccination On Amoxicillin Prescriptions In Older Adults: A Retrospective Cohort Study Using Primary Care Data, Lr Rodgers, Aj Streeter, N Lin, W Hamilton, We Henley Jan 2021

Impact Of Influenza Vaccination On Amoxicillin Prescriptions In Older Adults: A Retrospective Cohort Study Using Primary Care Data, Lr Rodgers, Aj Streeter, N Lin, W Hamilton, We Henley

Peninsula Medical School

Background Bacterial infections of the upper and lower respiratory tract are a frequent complication of influenza and contribute to the widespread use of antibiotics. Influenza vaccination may help reduce both appropriate and inappropriate prescribing of antibiotics. Electronic health records provide a rich source of information for assessing secondary effects of influenza vaccination. Methods We conducted a retrospective study to estimate effects of influenza vaccine on antibiotic (amoxicillin) prescription in the elderly based on data from the Clinical Practice Research Datalink. The introduction of UK policy to recommend the influenza vaccine to older adults in 2000 led to a substantial increase …


The Phylogenetic Structure Of Reptile, Avian And Uropathogenic Escherichia Coli With Particular Reference To Extraintestinal Pathotypes, Marta Książczyk, Bartłomiej Dudek, Maciej Kuczkowski, Robert O’Hara, Kamila Korzekwa, Anna Wzorek, Agnieszka Korzeniowska-Kowal, Mathew Upton, Adam Junka, Alina Wieliczko, Radosław Ratajszczak, Gabriela Bugla-Płoskońska Jan 2021

The Phylogenetic Structure Of Reptile, Avian And Uropathogenic Escherichia Coli With Particular Reference To Extraintestinal Pathotypes, Marta Książczyk, Bartłomiej Dudek, Maciej Kuczkowski, Robert O’Hara, Kamila Korzekwa, Anna Wzorek, Agnieszka Korzeniowska-Kowal, Mathew Upton, Adam Junka, Alina Wieliczko, Radosław Ratajszczak, Gabriela Bugla-Płoskońska

School of Biomedical Sciences

The impact of the Gram-negative bacterium Escherichia coli (E. coli) on the microbiomic and pathogenic phenomena occurring in humans and other warm-blooded animals is relatively well-recognized. At the same time, there are scant data concerning the role of E. coli strains in the health and disease of cold-blooded animals. It is presently known that reptiles are common asymptomatic carriers of another human pathogen, Salmonella, which, when transferred to humans, may cause a disease referred to as reptile-associated salmonellosis (RAS). We therefore hypothesized that reptiles may also be carriers of specific E. coli strains (reptilian Escherichia coli, RepEC) which may differ …


Adid-Unet—A Segmentation Model For Covid-19 Infection From Lung Ct Scans, Alex Noel Joseph Raj, Haipeng Zhu, Asiya Khan, Zhemin Zhuang, Zengbiao Yang, G. V.Vijayalakshmi Mahesh, Ganesan Karthik Jan 2021

Adid-Unet—A Segmentation Model For Covid-19 Infection From Lung Ct Scans, Alex Noel Joseph Raj, Haipeng Zhu, Asiya Khan, Zhemin Zhuang, Zengbiao Yang, G. V.Vijayalakshmi Mahesh, Ganesan Karthik

School of Engineering, Computing and Mathematics

No abstract provided.


Predicting Dominance Of Sand Transport By Waves, Tides And Their Interactions On Sandy Continental Shelves, Ev King, Dc Conley, G Masselink, N Leonardi Jan 2021

Predicting Dominance Of Sand Transport By Waves, Tides And Their Interactions On Sandy Continental Shelves, Ev King, Dc Conley, G Masselink, N Leonardi

School of Biological and Marine Sciences

No abstract provided.


Seasonal Monitoring Of Lipid Degradation Processes In The Western English Channel Links Bacterial 10s-Dox Enzyme Activity To Free Fatty Acid Production By Phytoplankton, Jean François Rontani, Lukas Smik, Frédéric Vaultier, Claire Widdicombe, Simon T. Belt Jan 2021

Seasonal Monitoring Of Lipid Degradation Processes In The Western English Channel Links Bacterial 10s-Dox Enzyme Activity To Free Fatty Acid Production By Phytoplankton, Jean François Rontani, Lukas Smik, Frédéric Vaultier, Claire Widdicombe, Simon T. Belt

School of Geography, Earth and Environmental Sciences

No abstract provided.


Synthesis Of Ultra‐Fine Co 1‐(X+Y) Ni X Zn Y Fe 2 O 4 Ferrite Nanoparticles: Customizing Magnetic Properties, S Khorshidian, B Vaseghi, G Rezaei, D Jenkins, N Kumar, A Rajan Jan 2021

Synthesis Of Ultra‐Fine Co 1‐(X+Y) Ni X Zn Y Fe 2 O 4 Ferrite Nanoparticles: Customizing Magnetic Properties, S Khorshidian, B Vaseghi, G Rezaei, D Jenkins, N Kumar, A Rajan

School of Engineering, Computing and Mathematics

Synthesis of ultrafine Co₁-(x+y)NixZnyFe₂O₄ magnetic nanoparticles with different chemical compositions is essential to study the magnetic fluid hyperthermia (MFH) as a treatment in which the superparamagnetic behaviour of materials is beneficial. In this paper, Co₁-(x+y)NiZnyFe₂O₄ magnetic nanoparticles with different x and y amounts were synthesized to find out a tuning pattern for magnetic properties, especially anisotropy constant to gain the best heating efficiency. We proved that the co-presence of ions will greatly affect the magnetic performance of our superparamagnetic nanoparticles in which Co₀.₅₉Zn₀.₄₁Fe₂O₄ for values of x = 0.00 and y = 0.41 exhibits the highest magnetic anisotropy constant after …


High-Resolution, Large-Scale Laboratory Measurements Of A Sandy Beach And Dynamic Cobble Berm Revetment, Chris E. Blenkinsopp, Paul M. Bayle, Daniel C. Conley, Gerd Masselink, Emily Gulson, Isabel Kelly, Rafael Almar, Ian L. Turner, Tom E. Baldock, Tomas Beuzen, Robert T. Mccall, Huub Rijper, Ad Reniers, Peter Troch, David Gallach-Sanchez, Alan J. Hunter, Oscar Bryan, Gwyn Hennessey, Peter Ganderton, Marion Tissier, Matthias Kudella, Stefan Schimmels Jan 2021

High-Resolution, Large-Scale Laboratory Measurements Of A Sandy Beach And Dynamic Cobble Berm Revetment, Chris E. Blenkinsopp, Paul M. Bayle, Daniel C. Conley, Gerd Masselink, Emily Gulson, Isabel Kelly, Rafael Almar, Ian L. Turner, Tom E. Baldock, Tomas Beuzen, Robert T. Mccall, Huub Rijper, Ad Reniers, Peter Troch, David Gallach-Sanchez, Alan J. Hunter, Oscar Bryan, Gwyn Hennessey, Peter Ganderton, Marion Tissier, Matthias Kudella, Stefan Schimmels

School of Biological and Marine Sciences

High quality laboratory measurements of nearshore waves and morphology change at, or near prototype-scale are essential to support new understanding of coastal processes and enable the development and validation of predictive models. The DynaRev experiment was completed at the GWK large wave flume over 8 weeks during 2017 to investigate the response of a sandy beach to water level rise and varying wave conditions with and without a dynamic cobble berm revetment, as well as the resilience of the revetment itself. A large array of instrumentation was used throughout the experiment to capture: (1) wave transformation from intermediate water depths …


Idealism, Pragmatism, And The Power Of Compromise In The Negotiation Of New Zealand's Zero Carbon Act, Ian Bailey, Oscar Fitch-Roy, Inderberg Th Jackson, David Benson Jan 2021

Idealism, Pragmatism, And The Power Of Compromise In The Negotiation Of New Zealand's Zero Carbon Act, Ian Bailey, Oscar Fitch-Roy, Inderberg Th Jackson, David Benson

School of Geography, Earth and Environmental Sciences

Discursive choices made by policy entrepreneurs are an important factor in the development of climate change acts (CCAs). This article examines the extent to which such choices reflect the strategic need for CCA entrepreneurs to compromise pragmatically and modulate their policy preferences in order to secure the agreement needed for CCA adoption. Drawing upon theoretical insights from discursive institutionalism (DI) and policy entrepreneurship, this article analyses discursive choices during negotiations surrounding the New Zealand Zero Carbon Act (ZCA). The analysis shows that endogenous political-ideological constraints compelled entrepreneurial actors to modify first-choice preferences for emissions reduction legislation by reframing their coordinative …


Graphene Oxide Biopolymer Aerogels For The Removal Of Lead From Drinking Water Using A Novel Nano-Enhanced Ion Exchange Cascade, J. M. Bloor, R. D. Handy, S. A. Awan, D. F.L. Jenkins Jan 2021

Graphene Oxide Biopolymer Aerogels For The Removal Of Lead From Drinking Water Using A Novel Nano-Enhanced Ion Exchange Cascade, J. M. Bloor, R. D. Handy, S. A. Awan, D. F.L. Jenkins

School of Engineering, Computing and Mathematics

No abstract provided.


Multiple Trophic Markers Trace Dietary Carbon Sources In Barents Sea Zooplankton During Late Summer, Doreen Kohlbach, Haakon Hop, Anette Wold, Katrin Schmidt, Lukas Smik, Simon T. Belt, Al-Habahbeh A Keck, Matthias Woll, Martin Graeve, Anna Maria Dąbrowska, Agnieszka Tatarek, Angus Atkinson, Philipp Assmy Jan 2021

Multiple Trophic Markers Trace Dietary Carbon Sources In Barents Sea Zooplankton During Late Summer, Doreen Kohlbach, Haakon Hop, Anette Wold, Katrin Schmidt, Lukas Smik, Simon T. Belt, Al-Habahbeh A Keck, Matthias Woll, Martin Graeve, Anna Maria Dąbrowska, Agnieszka Tatarek, Angus Atkinson, Philipp Assmy

School of Geography, Earth and Environmental Sciences

We investigated diets of 24 Barents Sea zooplankton taxa to understand pelagic food-web processes during late summer, including the importance of sea ice algae-produced carbon. This was achieved by combining insights derived from multiple and complementary trophic marker approaches to construct individual aspects of feeding. Specifically, we determined proportions of algal-produced fatty acids (FAs) to reflect the reliance on diatom- versus dinoflagellate-derived carbon, highly branched isoprenoid (HBI) lipids that distinguish between ice-associated and pelagic carbon sources, and sterols to indicate the degree of carnivory. Copepods had the strongest diatom signal based on FAs, while a lack of sea ice algae-associated …


A Novel Dietary Multi-Strain Yeast Fraction Modulates Intestinal Toll-Like-Receptor Signalling And Mucosal Responses Of Rainbow Trout (Oncorhynchus Mykiss), Mark Rawling, Eric Leclercq, Andrew Foey, Mathieu Castex, Daniel Merrifield Jan 2021

A Novel Dietary Multi-Strain Yeast Fraction Modulates Intestinal Toll-Like-Receptor Signalling And Mucosal Responses Of Rainbow Trout (Oncorhynchus Mykiss), Mark Rawling, Eric Leclercq, Andrew Foey, Mathieu Castex, Daniel Merrifield

School of Biological and Marine Sciences

No abstract provided.


Beyond Coral-Algal Regimes: High Taxonomic Resolution Surveys And Trait-Based Analyses Reveal Multiple Benthic Regimes, M Reverter, M Jackson, S Rohde, M Moeller, R Bara, Mt Lasut, Ms Reinach, Pj Schupp Jan 2021

Beyond Coral-Algal Regimes: High Taxonomic Resolution Surveys And Trait-Based Analyses Reveal Multiple Benthic Regimes, M Reverter, M Jackson, S Rohde, M Moeller, R Bara, Mt Lasut, Ms Reinach, Pj Schupp

School of Biological and Marine Sciences

No abstract provided.


Fibulin-2: A Novel Biomarker For Differentiating Grade Ii From Grade I Meningiomas, Agbolahan A. Sofela, David A. Hilton, Sylwia Ammoun, Daniele Baiz, Claire L. Adams, Emanuela Ercolano, Michael D. Jenkinson, Kathreena M. Kurian, Mario Teo, Peter C. Whitfield, Felix Sahm, C. Oliver Hanemann Jan 2021

Fibulin-2: A Novel Biomarker For Differentiating Grade Ii From Grade I Meningiomas, Agbolahan A. Sofela, David A. Hilton, Sylwia Ammoun, Daniele Baiz, Claire L. Adams, Emanuela Ercolano, Michael D. Jenkinson, Kathreena M. Kurian, Mario Teo, Peter C. Whitfield, Felix Sahm, C. Oliver Hanemann

Peninsula Medical School

There is an unmet need for the identification of biomarkers to aid in the diagnosis, clinical management, prognosis and follow-up of meningiomas. There is currently no consensus on the optimum management of WHO grade II meningiomas. In this study, we identified the calcium binding extracellular matrix glycoprotein, Fibulin-2, via mass-spectrometry-based proteomics, assessed its expression in grade I and II meningiomas and explored its potential as a grade II biomarker. A total of 87 grade I and 91 grade II different meningioma cells, tissue and plasma samples were used for the various experimental techniques employed to assess Fibulin-2 expression. The tumours …


Effect Of Ageing And Hypertension On The Expression And Activity Of Pept2 In Normal And Hypertrophic Hearts, Othman Alghamdi, Nicola King, Graham L. Jones, Pierre D.J. Moens Jan 2021

Effect Of Ageing And Hypertension On The Expression And Activity Of Pept2 In Normal And Hypertrophic Hearts, Othman Alghamdi, Nicola King, Graham L. Jones, Pierre D.J. Moens

School of Biomedical Sciences

Some dipeptides have been implicated in myocardial protection, but little is known about their membrane transporter PEPT2. The aim of this study was to determine whether the expression and activity of the cardiac-type PEPT2 cotransporter could be affected by ageing and/or hypertension. Sarcolemmal vesicles (SV) were isolated from the hearts of all rat groups using a standard procedure to investigate the transport activity and protein abundance by fluorescence spectroscopy and Western blot, respectively. SLC15A2 “PEPT2” gene expression was relatively quantified by RT-qPCR. In the Wistar rat groups, the protein and gene expression of PEPT2 were upregulated with ageing. These changes …


Palaeozoic Stromatoporoids And Chaetetids Analysed Using Electron Backscatter Diffraction (Ebsd); Implications For Original Mineralogy And Microstructure, Uwe Balthasar, Stephen Kershaw, Silva A-C Da, Barbara Seuss, Maggie Cusack, Kilian Eichenseer, Peter Chung Jan 2021

Palaeozoic Stromatoporoids And Chaetetids Analysed Using Electron Backscatter Diffraction (Ebsd); Implications For Original Mineralogy And Microstructure, Uwe Balthasar, Stephen Kershaw, Silva A-C Da, Barbara Seuss, Maggie Cusack, Kilian Eichenseer, Peter Chung

School of Geography, Earth and Environmental Sciences

No abstract provided.


Group 2i Isochrysidales Produce Characteristic Alkenones Reflecting Sea Ice Distribution, Karen Jiaxi Wang, Yongsong Huang, Markus Majaneva, Simon T. Belt, Sian Liao, Joseph Novak, Tyler R. Kartzinel, Timothy D. Herbert, Nora Richter, Patricia Cabedo-Sanz Jan 2021

Group 2i Isochrysidales Produce Characteristic Alkenones Reflecting Sea Ice Distribution, Karen Jiaxi Wang, Yongsong Huang, Markus Majaneva, Simon T. Belt, Sian Liao, Joseph Novak, Tyler R. Kartzinel, Timothy D. Herbert, Nora Richter, Patricia Cabedo-Sanz

School of Geography, Earth and Environmental Sciences

Alkenones are biomarkers produced solely by algae in the order Isochrysidales that have been used to reconstruct sea surface temperature (SST) since the 1980s. However, alkenone-based SST reconstructions in the northern high latitude oceans show significant bias towards warmer temperatures in core-tops, diverge from other SST proxies in down core records, and are often accompanied by anomalously high relative abundance of the C37 tetra-unsaturated methyl alkenone (%C37:4). Elevated %C37:4 is widely interpreted as an indicator of low sea surface salinity from polar water masses, but its biological source has thus far remained elusive. Here we identify a lineage of Isochrysidales …


The Identification Of Biomarker Differences Between Grade I And Ii Meningiomas: Fibulin-2 Is A Novel Biomarker For Differentiating Grade Ii From Grade I Meningiomas, Agbolahan Sofela Jan 2021

The Identification Of Biomarker Differences Between Grade I And Ii Meningiomas: Fibulin-2 Is A Novel Biomarker For Differentiating Grade Ii From Grade I Meningiomas, Agbolahan Sofela

Other Faculty of Health Theses

Background: There is an unmet need for the identification of biomarkers to aid in the diagnosis, clinical management, prognosis and follow-up of meningiomas, facilitated by recent advances in meningioma genomics. WHO grade II meningiomas remain a controversial group of CNS tumours to diagnose/treat, compared to the more prevalent and extensively researched grade I tumours. Aim: To identify molecular signatures (biomarkers) unique to grade II meningiomas (versus grade I). Methods: I combined literature review with an unbiased global proteomic analysis of four grade I and four grade II primary (meningioma) cell cultures, to identify proteins differentially expressed between both grades. Validation …