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Ethercat Implementation Of A Variable-Stiffness Tendon Drive With Non-Back-Drivable Worm-Gear Motor Actuation, Ian S. Howard, Martin F. Stoelen Jul 2021

Ethercat Implementation Of A Variable-Stiffness Tendon Drive With Non-Back-Drivable Worm-Gear Motor Actuation, Ian S. Howard, Martin F. Stoelen

School of Engineering, Computing and Mathematics

No abstract provided.


Lithothamnion Species (Hapalidiales, Rhodophyta) In The Arctic And Subarctic: Providing A Systematics Foundation In A Time Of Rapid Climate Change, V Pena, D Belanger, P Gagnon, Jl Richards, Gall L Le, Jr Hughey, Gw Saunders, Sc Lindstrom, E Rinde, V Husa, H Christie, S Fredriksen, Jm Hall-Spencer, Rs Steneck, Km Schoenrock, J Gitmark, Es Grefsrud, Mba D'Auriac, E Legrand, J Grall, Tm Mumford, Na Kamenos, Pw Gabrielson Jul 2021

Lithothamnion Species (Hapalidiales, Rhodophyta) In The Arctic And Subarctic: Providing A Systematics Foundation In A Time Of Rapid Climate Change, V Pena, D Belanger, P Gagnon, Jl Richards, Gall L Le, Jr Hughey, Gw Saunders, Sc Lindstrom, E Rinde, V Husa, H Christie, S Fredriksen, Jm Hall-Spencer, Rs Steneck, Km Schoenrock, J Gitmark, Es Grefsrud, Mba D'Auriac, E Legrand, J Grall, Tm Mumford, Na Kamenos, Pw Gabrielson

School of Biological and Marine Sciences

No abstract provided.


Coralline Algae At Increased Co2: A Global Response To Ocean Acidification, V Pena, B Harvey, S Agostini, L Porzio, M Milazzo, P Horta, Gall L Le, J Hall-Spencer Jul 2021

Coralline Algae At Increased Co2: A Global Response To Ocean Acidification, V Pena, B Harvey, S Agostini, L Porzio, M Milazzo, P Horta, Gall L Le, J Hall-Spencer

School of Biological and Marine Sciences

Coralline algae are an ecologically important part of benthic communities worldwide and there is growing concern that ocean acidification can severely impact their calcite skeletons. Laboratory studies of coralline algae in simulated ocean acidification conditions have revealed wide response variability, making it difficult to assess their future biodiversity and contribution to ecosystem function. Here, we used natural gradients in seawater carbonate chemistry in widely separated biogeographic regions (Mediterranean, NW Pacific) to investigate the effects of ocean acidification on coralline algal biodiversity, abundance and skeletal mineralogy. Molecular identification showed a decrease in the taxonomic diversity of coralline algae with increasing acidification …


State Space Analysis Of Variable-Stiffness Tendon Drive With Non-Back-Drivable Worm-Gear Motor Actuation, Ian S. Howard, Martin F. Stoelen Jul 2021

State Space Analysis Of Variable-Stiffness Tendon Drive With Non-Back-Drivable Worm-Gear Motor Actuation, Ian S. Howard, Martin F. Stoelen

School of Engineering, Computing and Mathematics

No abstract provided.


Effects Of Vegetation, Sediment Supply And Sea Level Rise On The Morphodynamic Evolution Of Tidal Channels, A Sgarabotto, A D'Alpaos, S Lanzoni Jul 2021

Effects Of Vegetation, Sediment Supply And Sea Level Rise On The Morphodynamic Evolution Of Tidal Channels, A Sgarabotto, A D'Alpaos, S Lanzoni

School of Geography, Earth and Environmental Sciences

Tidal channels play a leading role in the morphodynamic evolution of tidal environments by driving the exchange of water, sediments, and nutrients within these systems. Despite their fundamental function on landscape construction, current knowledge on their plano‐altimetric evolution in response to environmental forcing is still limited. We developed a mathematical model to address the interplay of biogeomorphic processes on the plano‐altimetric equilibrium of a straight tidal channel flanked by adjacent intertidal platforms. The model couples a one‐dimensional hydrodynamic model with a bed evolution model. The former describes the flow field within the channel and the storage contribution of lateral shoals. …


The Genetics Of Parkinson’S Disease And Implications For Clinical Practice, Jacob Oliver Day, Stephen Mullin Jun 2021

The Genetics Of Parkinson’S Disease And Implications For Clinical Practice, Jacob Oliver Day, Stephen Mullin

Peninsula Medical School

The genetic landscape of Parkinson’s disease (PD) is characterised by rare high penetrance pathogenic variants causing familial disease, genetic risk factor variants driving PD risk in a significant minority in PD cases and high frequency, low penetrance variants, which contribute a small increase of the risk of developing sporadic PD. This knowledge has the potential to have a major impact in the clinical care of people with PD. We summarise these genetic influences and discuss the implications for therapeutics and clinical trial design.


Dietary Exposure To Copper Sulphate Compared To A Copper Oxide Nanomaterial In Rainbow Trout: Bioaccumulation With Minimal Physiological Effects., David Boyle, Nathaniel J. Clark, Benjamin P. Eynon, Richard D. Handy Jun 2021

Dietary Exposure To Copper Sulphate Compared To A Copper Oxide Nanomaterial In Rainbow Trout: Bioaccumulation With Minimal Physiological Effects., David Boyle, Nathaniel J. Clark, Benjamin P. Eynon, Richard D. Handy

School of Health Professions

The dietary bioaccumulation potential of engineered nanomaterials (ENMs) remains poorly understood. The aim of the current study was to assess the dietary bioaccumulation of copper from copper oxide (CuO) ENMs...


A Clinical Study To Optimise A Sand Fly Biting Protocol For Use In A Controlled Human Infection Model Of Cutaneous Leishmaniasis (The Flybite Study), Vivak Parkash, Helen Ashwin, Jovana Sadlova, Barbora Vojtkova, Georgina Jones, Nina Martin, Elizabeth Greensted, Victoria Allgar, Shaden Kamhawi, Jesus G. Valenzuela, Alison M. Layton, Charles L. Jaffe, Petr Volf, Paul M. Kaye, Charles J.N. Lacey Jun 2021

A Clinical Study To Optimise A Sand Fly Biting Protocol For Use In A Controlled Human Infection Model Of Cutaneous Leishmaniasis (The Flybite Study), Vivak Parkash, Helen Ashwin, Jovana Sadlova, Barbora Vojtkova, Georgina Jones, Nina Martin, Elizabeth Greensted, Victoria Allgar, Shaden Kamhawi, Jesus G. Valenzuela, Alison M. Layton, Charles L. Jaffe, Petr Volf, Paul M. Kaye, Charles J.N. Lacey

Peninsula Medical School

Background: Leishmaniasis is a globally important yet neglected parasitic disease transmitted by phlebotomine sand flies. With new candidate vaccines in or near the clinic, a controlled human challenge model (CHIM) using natural sand fly challenge would provide a method for early evaluation of prophylactic efficacy. Methods: We evaluated the biting frequency and adverse effects resulting from exposure of human volunteers to bites of either Phlebotomus papatasi or P. duboscqi, two natural vectors of Leishmania major. 12 healthy participants were recruited (mean age 40.2 ± 11.8 years) with no history of significant travel to regions where L. major-transmitting sand flies are …


Archaeology And Agriculture: Plants, People And Past Land-Use, Vareilles A De, Ruth Pelling, Jessie Woodbridge, Ralph Fyfe Jun 2021

Archaeology And Agriculture: Plants, People And Past Land-Use, Vareilles A De, Ruth Pelling, Jessie Woodbridge, Ralph Fyfe

School of Geography, Earth and Environmental Sciences

No abstract provided.


Quantum Brain Networks: A Perspective, E Miranda, S Venkatesh, C Hernani-Morales, L Lamata, Jd Martin-Guerrero, E Solano Jun 2021

Quantum Brain Networks: A Perspective, E Miranda, S Venkatesh, C Hernani-Morales, L Lamata, Jd Martin-Guerrero, E Solano

School of Art, Design and Architecture

No abstract provided.


Outcomes Of Gonioscopy-Assisted Transluminal Trabeculotomy In Pseudoexfoliative Glaucoma: 24-Month Follow-Up, Eamon Sharkawi, Daniel Josef Lindegger, Paul H. Artes, Lydia Lehmann-Clarke, Wardani M El, Marie Misteli, Jérôme Pasquier, Adriano Guarnieri Jun 2021

Outcomes Of Gonioscopy-Assisted Transluminal Trabeculotomy In Pseudoexfoliative Glaucoma: 24-Month Follow-Up, Eamon Sharkawi, Daniel Josef Lindegger, Paul H. Artes, Lydia Lehmann-Clarke, Wardani M El, Marie Misteli, Jérôme Pasquier, Adriano Guarnieri

School of Health Professions

Aim To report on outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) in eyes with pseudoexfoliative glaucoma (PXG). Methods Prospective, interventional, non-comparative case series. A total of 103 eyes from 84 patients with PXG were enrolled to undergo a 360-degree ab interno trabeculotomy with gonioscopic assistance using either a 5.0 polypropylene suture or an illuminated microcatheter with up to 24 months of follow-up. Main outcome measures were intraocular pressure (IOP), number of antiglaucoma medications, success rate (IOP reduction ≥20% from baseline or IOP between 6 and 21 mm Hg, without further glaucoma surgery) and complication rate. Results Mean preoperative IOP was 27.1 …


Environmental Drivers Of Reef Manta Ray (Mobula Alfredi) Visitation Patterns To Key Aggregation Habitats In The Maldives, Joanna L. Harris, Guy M.W. Stevens Jun 2021

Environmental Drivers Of Reef Manta Ray (Mobula Alfredi) Visitation Patterns To Key Aggregation Habitats In The Maldives, Joanna L. Harris, Guy M.W. Stevens

School of Biological and Marine Sciences

A detailed understanding of the dynamics of small-scale (10s km) habitat use by the reef manta ray (Mobula alfredi) in the Maldives Archipelago is required to develop an effective national conservation management plan for this wide-ranging species. Here, a combination of photo-ID sightings data and acoustic telemetry were used to investigate both long-term M. alfredi visitation trends and small-scale movement patterns to key habitats on the eastern side of Baa Atoll (Hanifaru Bay feeding area, Dhigu Thila multifunctional site, and Nelivaru Thila cleaning station). All tagged and most of the sighted M. alfredi exhibited high affinity to the eastern side …


Zanubrutinib For The Treatment Of Relapsed Or Refractory Mantle Cell Lymphoma, Cs Tam, S Opat, D Simpson, G Cull, Et Al Jun 2021

Zanubrutinib For The Treatment Of Relapsed Or Refractory Mantle Cell Lymphoma, Cs Tam, S Opat, D Simpson, G Cull, Et Al

Peninsula Medical School

Zanubrutinib, a highly selective Bruton tyrosine kinase inhibitor, was evaluated in a phase 1/2 study in patients with various B-cell malignancies. In the subgroup of patients with relapsed/refractory (R/R) mantle cell lymphoma (MCL), zanubrutinib was administered as 160 mg twice daily (n = 14), 320 mg once daily (n = 18), or =160 mg total dose (n = 5). Herein, we report results for patients receiving a total daily dose of 320 mg (N = 32). Median study follow-up was 18.8 months. Eighteen patients discontinued treatment, 10 because of progressive disease and 8 because of adverse events (AEs); 1 AE …


Respiratory Parameters For The Classification Of Dysfunctional Insulin Secretion By Pancreatic Islets, Uma D. Kabra, Charles Affourtit, Martin Jastroch Jun 2021

Respiratory Parameters For The Classification Of Dysfunctional Insulin Secretion By Pancreatic Islets, Uma D. Kabra, Charles Affourtit, Martin Jastroch

School of Biomedical Sciences

The development of obesity and type 2 diabetes (T2D) has been associated with impaired mitochondrial function. In pancreatic beta (β) cells, mitochondrial energy metabolism plays a central role in triggering and controlling glucose-stimulated insulin secretion (GSIS). Here, we have explored whether mitochondrial bioenergetic parameters assessed with Seahorse extracellular flux technology can quantitatively predict insulin secretion. We metabolically stressed male C57BL/6 mice by high-fat feeding (HFD) and measured the glucose sensitivity of islet respiration and insulin secretion. The diet-induced obese (DIO) mice developed hyperinsulinemia, but no pathological secretory differences were apparent between isolated DIO and chow islets. Real-time extracellular flux analysis, …


Biomarkers For Differentiating Grade Ii Meningiomas From Grade I: A Systematic Review, Agbolahan A. Sofela, Lucy Mcgavin, Peter C. Whitfield, C. Oliver Hanemann Jun 2021

Biomarkers For Differentiating Grade Ii Meningiomas From Grade I: A Systematic Review, Agbolahan A. Sofela, Lucy Mcgavin, Peter C. Whitfield, C. Oliver Hanemann

Peninsula Medical School

Introduction: There are a number of prognostic markers (methylation, CDKN2A/B) described to be useful for the stratification of meningiomas. However, there are currently no clinically validated biomarkers for the preoperative prediction of meningioma grade, which is determined by the histological analysis of tissue obtained from surgery. Accurate preoperative biomarkers would inform the pre-surgical assessment of these tumours, their grade and prognosis and refine the decision-making process for treatment. This review is focused on the more controversial grade II tumours, where debate still surrounds the need for adjuvant therapy, repeat surgery and frequency of follow up. Methods: We evaluated current literature …


The Severe Asthma Questionnaire: Sensitivity To Change And Minimal Clinically Important Difference (Mcid), Matthew Masoli, Joseph W. Lanario, Michael E. Hyland, Andrew Menzies-Gow, Adel H. Mansur, David Allen, James W. Dodd, Gemma Hayes, Jose M. Valderas, Sarah E. Lamb, Rupert C. Jones Jun 2021

The Severe Asthma Questionnaire: Sensitivity To Change And Minimal Clinically Important Difference (Mcid), Matthew Masoli, Joseph W. Lanario, Michael E. Hyland, Andrew Menzies-Gow, Adel H. Mansur, David Allen, James W. Dodd, Gemma Hayes, Jose M. Valderas, Sarah E. Lamb, Rupert C. Jones

More Faculty of Health Research

No abstract provided.


Lithothamnion (Hapalidiales, Rhodophyta) In The Changing Arctic And Subarctic: Dna Sequencing Of Type And Recent Specimens Provides A Systematics Foundation*, Viviana Peña, David Bélanger, Patrick Gagnon, Joseph L. Richards, Gall L Le, Jeffery R. Hughey, Gary W. Saunders, Sandra C. Lindstrom, Eli Rinde, Vivian Husa, Hartvig Christie, Stein Fredriksen, Jason M. Hall-Spencer, Robert S. Steneck, Kathryn M. Schoenrock, Janne Gitmark, Ellen Sofie Grefsrud, D’Auriac Mb Anglès, Erwann Legrand, Jacques Grall, Thomas F. Mumford, Nicholas A. Kamenos, Paul W. Gabrielson Jun 2021

Lithothamnion (Hapalidiales, Rhodophyta) In The Changing Arctic And Subarctic: Dna Sequencing Of Type And Recent Specimens Provides A Systematics Foundation*, Viviana Peña, David Bélanger, Patrick Gagnon, Joseph L. Richards, Gall L Le, Jeffery R. Hughey, Gary W. Saunders, Sandra C. Lindstrom, Eli Rinde, Vivian Husa, Hartvig Christie, Stein Fredriksen, Jason M. Hall-Spencer, Robert S. Steneck, Kathryn M. Schoenrock, Janne Gitmark, Ellen Sofie Grefsrud, D’Auriac Mb Anglès, Erwann Legrand, Jacques Grall, Thomas F. Mumford, Nicholas A. Kamenos, Paul W. Gabrielson

School of Biological and Marine Sciences

No abstract provided.


Concept Libraries For Automatic Electronic Health Record Based Phenotyping: A Review., Za Almowil, S-M Zhou, S Brophy Jun 2021

Concept Libraries For Automatic Electronic Health Record Based Phenotyping: A Review., Za Almowil, S-M Zhou, S Brophy

School of Nursing and Midwifery

INTRODUCTION: Electronic health records (EHR) are linked together to examine disease history and to undertake research into the causes and outcomes of disease. However, the process of constructing algorithms for phenotyping (e.g., identifying disease characteristics) or health characteristics (e.g., smoker) is very time consuming and resource costly. In addition, results can vary greatly between researchers. Reusing or building on algorithms that others have created is a compelling solution to these problems. However, sharing algorithms is not a common practice and many published studies do not detail the clinical code lists used by the researchers in the disease/characteristic definition. To address …


Satellite-Derived Shoreline Detection At A High-Energy Meso-Macrotidal Beach, Bruno Castelle, Gerd Masselink, Tim Scott, Christopher Stokes, Aikaterini Konstantinou, Vincent Marieu, Stéphane Bujan Jun 2021

Satellite-Derived Shoreline Detection At A High-Energy Meso-Macrotidal Beach, Bruno Castelle, Gerd Masselink, Tim Scott, Christopher Stokes, Aikaterini Konstantinou, Vincent Marieu, Stéphane Bujan

School of Biological and Marine Sciences

Publicly available satellite imagery can now provide multi-decadal time series of shoreline data from local to global scale, enabling analysis of sandy beach shoreline variability across a spectrum of temporal scales. Such data can, however, be associated with large uncertainties, particularly for beaches experiencing a large tidal range (>2 m) and energetic incident waves. We use a decade of bi-monthly topographic surveys at the high-energy meso-macrotidal beach of Truc Vert, southwest France, and concurrent wave and water-level hindcast to investigate the uncertainties associated with satellite-derived time series of the shoreline position. We show that consideration of the water level …


Uk B.1.1.7 Variant Exhibits Increased Respiratory Replication And Shedding In Nonhuman Primates, K Rosenke, F Feldmann, A Okumura, F Hansen, T Tang-Huau, K Meade-White, B Kaza, Bj Smith, Pw Hanley, J Lovaglio, Ma Jarvis, C Shaia, H Feldmann Jun 2021

Uk B.1.1.7 Variant Exhibits Increased Respiratory Replication And Shedding In Nonhuman Primates, K Rosenke, F Feldmann, A Okumura, F Hansen, T Tang-Huau, K Meade-White, B Kaza, Bj Smith, Pw Hanley, J Lovaglio, Ma Jarvis, C Shaia, H Feldmann

School of Biomedical Sciences

No abstract provided.


Loc680254 Regulates Schwann Cell Proliferation Through Psrc1 And Ska1 As A Microrna Sponge Following Sciatic Nerve Injury, C Yao, Q Wang, Y Wang, J Wu, Et Al Jun 2021

Loc680254 Regulates Schwann Cell Proliferation Through Psrc1 And Ska1 As A Microrna Sponge Following Sciatic Nerve Injury, C Yao, Q Wang, Y Wang, J Wu, Et Al

Peninsula Medical School

Peripheral nerve injury triggers sequential phenotype alterations in Schwann cells, which are critical for axonal regeneration. Long noncoding RNAs (lncRNAs) are long transcripts without obvious coding potential. It has been reported that lncRNAs participate in diverse biological processes and diseases. However, the role of lncRNA in Schwann cells and peripheral nerve regeneration is unclear. Here, we identified an lncRNA, loc680254, which is upregulated in rat sciatic nerve after peripheral nerve injury. The loc680254 knockdown inhibits Schwann cell proliferation, enhances apoptosis, and hinders cell cycle, while loc680254 overexpression has the opposite effect. Mechanically, we found that loc680254 might act as a …


Editorial: Bacteriocins And Other Ribosomally Synthesised And Post-Translationally Modified Peptides (Ripps) As Alternatives To Antibiotics, Harsh Mathur, Des Field, Mathew Upton, Paul D. Cotter Jun 2021

Editorial: Bacteriocins And Other Ribosomally Synthesised And Post-Translationally Modified Peptides (Ripps) As Alternatives To Antibiotics, Harsh Mathur, Des Field, Mathew Upton, Paul D. Cotter

School of Biomedical Sciences

This Research Topic concerns bacteriocins and others RiPPs (Ribosomally synthesized and Post-translationally modified Peptides) as alternatives to antibiotics. Due to the increasing problem of antibiotic resistance globally, there is a pressing need to source such alternative antimicrobials. Here, in this editorial, we summarize the key papers that were published as part of this Research Topic, which consisted of a diverse range of research as well as review articles, pertaining to several different bacteriocins and RiPPs.


Testing Cost Containment Of Future Health Care With Maintained Or Improved Quality – The Cost Cares Project Running Title: Cost Containment Of Future Health Care, Karl Swedberg, Helen M. Lloyd Jun 2021

Testing Cost Containment Of Future Health Care With Maintained Or Improved Quality – The Cost Cares Project Running Title: Cost Containment Of Future Health Care, Karl Swedberg, Helen M. Lloyd

School of Psychology

No abstract provided.


Study The Influence Of Waxy Wheat Flour, Inulin And Guar Gum On Quality And Microstructure Of Pita And Tandoori Breads: Response Surface Methodology Aids Functional Food Development, Yaseen Galali, Gail Rees, Victor Kuri Jun 2021

Study The Influence Of Waxy Wheat Flour, Inulin And Guar Gum On Quality And Microstructure Of Pita And Tandoori Breads: Response Surface Methodology Aids Functional Food Development, Yaseen Galali, Gail Rees, Victor Kuri

School of Biomedical Sciences

No abstract provided.


Exploring Controls Of The Early And Stepped Deglaciation On The Western Margin Of The British Irish Ice Sheet., Sara Benetti, Richard C. Chiverrell, Cofaigh C O, Matt Burke, Alicia Medialdea, David Small, Colin Ballantyne, Mark D. Bateman, S. Louise Callard, Peter Wilson, Derek Fabel, Chris D. Clark, Riccardo Arosio, Sarah Bradley, Paul Dunlop, Jeremy C. Ely, Jenny Gales, Stephen J. Livingstone, Steven G. Moreton, Catriona Purcell, Margot Saher, Kevin Schiele, Landeghem K Van, Kasper Weilbach Jun 2021

Exploring Controls Of The Early And Stepped Deglaciation On The Western Margin Of The British Irish Ice Sheet., Sara Benetti, Richard C. Chiverrell, Cofaigh C O, Matt Burke, Alicia Medialdea, David Small, Colin Ballantyne, Mark D. Bateman, S. Louise Callard, Peter Wilson, Derek Fabel, Chris D. Clark, Riccardo Arosio, Sarah Bradley, Paul Dunlop, Jeremy C. Ely, Jenny Gales, Stephen J. Livingstone, Steven G. Moreton, Catriona Purcell, Margot Saher, Kevin Schiele, Landeghem K Van, Kasper Weilbach

School of Biological and Marine Sciences

No abstract provided.


Patient‐Centred Measurement Of Recovery From Day‐Case Surgery Using Wrist Worn Accelerometers: A Pilot And Feasibility Study, Am Ratcliffe, B Zhai, Y Guan, Dg Jackson, Et Al Jun 2021

Patient‐Centred Measurement Of Recovery From Day‐Case Surgery Using Wrist Worn Accelerometers: A Pilot And Feasibility Study, Am Ratcliffe, B Zhai, Y Guan, Dg Jackson, Et Al

Peninsula Medical School

This pilot and feasibility study evaluated wrist‐worn accelerometers to measure recovery from day‐case surgery in comparison with daily quality of recovery‐15 scores. The protocol was designed with extensive patient and public involvement and engagement, and delivered by a research network of anaesthesia trainees. Forty‐eight patients recruited through pre‐operative assessment clinics wore wrist accelerometers for 7 days before (pre‐operative) and immediately after elective surgery (early postoperative), and again at 3 months (late postoperative). Validated activity and quality of recovery questionnaires were administered. Raw accelerometry data were archived and analysed using open source software. The mean (SD) number of valid days of …


Trace Fossils In The Permian Rocks Of English Riviera Unesco Global Geopark, Malcolm B. Hart, Christopher W. Smart Jun 2021

Trace Fossils In The Permian Rocks Of English Riviera Unesco Global Geopark, Malcolm B. Hart, Christopher W. Smart

School of Geography, Earth and Environmental Sciences

The Permian breccias, conglomerates and sandstones of the English Riviera UNESCO Global Geopark were deposited in quite harsh, desert environments just north of the Permian Equator. Body fossil evidence is completely lacking but rare trace fossils provide evidence of a land-based community. There is a variety of traces present, probably indicative of the presence of a range of unknown animals. Though these animals cannot be identified, their occurrence is important in the understanding of the biodiversity of these Permian environments.


The Effect Of Ph, Calcium, Phosphate And Humic Acid On Cadmium Availability And Speciation In Artificial Groundwater, Nadia Jebril, Rich Boden, Charlotte Braungardt May 2021

The Effect Of Ph, Calcium, Phosphate And Humic Acid On Cadmium Availability And Speciation In Artificial Groundwater, Nadia Jebril, Rich Boden, Charlotte Braungardt

School of Biological and Marine Sciences

The interface between the ions in groundwater affects the biogeochemical behaviour of metal, and metal bioremediate by bacteria. Therefore, this study was aimed to predict the influence of pH, calcium, phosphate and humic acid on cadmium availability in artificial groundwater (AGW). Speciation and the thermodynamic calculation (MINTEQ program) were used to predict this in AGW theoretically. In results, cadmium availability diminished with an increase in pH, increase of calcium concentration and the addition of phosphate and humic acid of AGW. According to MINTEQ program, cadmium binds to some cations leaving fewer free cadmium ions available in AGW such as CdHCO3+, …


The Isolation And Identification Of Cadmium-Resistant Brevibacillus Agri C15, Nadia Jebril, Rich Boden, Charlotte Braungardt May 2021

The Isolation And Identification Of Cadmium-Resistant Brevibacillus Agri C15, Nadia Jebril, Rich Boden, Charlotte Braungardt

School of Biological and Marine Sciences

Eight Cd-resistant bacteria were isolated from the soil. Based on the resistance and specific growth rate, one isolate from these was chosen. The 16S rRNA (rrs) gene sequence was used to assert this isolate belongs to the genus of Brevibacillus and closely related to Brevibacillus agri (B.agri) DSM 6348T (AB112716). The isolate was termed B.agri C15. The specific growth yields and the Cd-dependent fall in specific growth yield of B.agri C15 was determined under different concentrations of Cd. The current study provides a basis for isolation Cd resistant bacteria with maximum tolerable concentration (MTC) 15 mM Cd from a contaminated …


Addition Of Composted Green Waste And Ericoid Mycorrhizal Fungi Fails To Facilitate Establishment Of Atlantic Heathland Species, Mary Lane, Mick E. Hanley, Paul Lunt, Mairi E. Knight, Charlotte B. Braungardt, Jon S. Ellis May 2021

Addition Of Composted Green Waste And Ericoid Mycorrhizal Fungi Fails To Facilitate Establishment Of Atlantic Heathland Species, Mary Lane, Mick E. Hanley, Paul Lunt, Mairi E. Knight, Charlotte B. Braungardt, Jon S. Ellis

School of Biological and Marine Sciences

Post-mining restoration of heathland habitats has met with mixed success. Failures are often ascribed to the complexity of replicating soil conditions: a scarcity of organic matter and microbial symbionts in stored overburden used for restoration is frequently implicated. Nonetheless, systematic investigation of the role of both interventions is lacking. Using a greenhouse trial and a large-scale field experiment within a commercial kaolinite mine site, we explored how the addition of ericoid mycorrhizal fungi (ErMF) and organic matter influenced the establishment of dwarf ericoid species that characterize NW European Atlantic lowland heaths. Neither intervention had any positive effect on ericoid establishment …