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That's It We're Having More Insulation: Will Householders Change Behaviours And Attitudes After Being Shown An Infrared Image Of Their Homes Leaking Heat?, Tc Auburn, J Goodhew, S Pahl Jul 2008

That's It We're Having More Insulation: Will Householders Change Behaviours And Attitudes After Being Shown An Infrared Image Of Their Homes Leaking Heat?, Tc Auburn, J Goodhew, S Pahl

School of Psychology

This longitudinal study explored the impact of showing householders infrared images (of their homes leaking heat) on energy consumption and attitudes.


Factors That Affect Cardiovascular Health: A Review, Sarah A. Buckingham Jul 2008

Factors That Affect Cardiovascular Health: A Review, Sarah A. Buckingham

The Plymouth Student Scientist

Cardiovascular disease is a major public health problem in terms of both high morbidity and mortality rates and large economic costs. Cardiovascular health and risk of disease are determined by a wide range of genetic and environmental factors. This review focuses on the extent to which heredity, physical activity, diet, and psychological factors (including stress) are known to contribute to cardiovascular health or disease. A predisposition for cardiovascular disease can be inherited, but genetic counselling allows the identification of those who are most at risk and an individualised plan to include appropriate lifestyle changes can then be formulated. It is …


The Effect Of Nucleotide-Binding Oligomerization Domain (Nod) Proteins On The Secretion Of Cytokines From Macrophages, Joanne Aggett Jul 2008

The Effect Of Nucleotide-Binding Oligomerization Domain (Nod) Proteins On The Secretion Of Cytokines From Macrophages, Joanne Aggett

The Plymouth Student Scientist

The study of Nucleotide-Binding Oligomerization Domain (NOD) Proteins is a very new area of immunology, with the gene for NOD2 having only been mapped in 2001 (Ogura et al 2001). It holds particular significance for those researching autoimmune disorders such as Blau syndrome and Crohns Disease (CD), as it has been found that a mutation in the NOD2 gene is present in a substantial proportion of CD sufferers, and having the mutation increases a person‟s susceptibility to developing the disease later in life (Economou et al 2004). This review will look at the current research surrounding the NOD proteins and …


Do Anxiety Level And Anxiety-Related Content Affect Accuracy And Endorsement Rate On Syllogistic Reasoning By Increasing Reliance On Belief-Biased Heuristic Processing?, Daniel Zahra Jul 2008

Do Anxiety Level And Anxiety-Related Content Affect Accuracy And Endorsement Rate On Syllogistic Reasoning By Increasing Reliance On Belief-Biased Heuristic Processing?, Daniel Zahra

The Plymouth Student Scientist

This study used an adaptation of the belief bias paradigm and correlational analyses to investigate the effects of validity, believability, content, and anxiety level on syllogistic reasoning in a sample comprised of undergraduate students and volunteers from the general population within a dual process framework. All the variables were found to affect reasoning accuracy, but content did not affect endorsement rate. These patterns of responding were not due solely to working memory differences, and accuracy decreases in high-anxious participants were found not to be due to a reliance on belief-biased processing resulting from working memory depletion, thus suggesting that what …


Nutrient Intakes At Lunchtime Of Primary School Children In Cornwall: A Comparison Of School Meals And Packed Lunches, G. A. Rees, C. J. Richards, J. Gregory Jul 2008

Nutrient Intakes At Lunchtime Of Primary School Children In Cornwall: A Comparison Of School Meals And Packed Lunches, G. A. Rees, C. J. Richards, J. Gregory

The Plymouth Student Scientist

No abstract provided.


Is Cardiovascular Health Affected By Exercise Type And Impact?, Sarah A. Buckingham Jul 2008

Is Cardiovascular Health Affected By Exercise Type And Impact?, Sarah A. Buckingham

The Plymouth Student Scientist

The principal aim of this study was to determine whether cardiovascular health, assessed by resting systolic and diastolic blood pressure and resting heart rate, was affected by exercise type (golf vs. tennis) and associated impact (low vs. high). Male and female golfers (n = 40) and tennis players (n = 40) aged between 40 and 71 years completed a short questionnaire relating to their main sport and typical exercise habits. Resting blood pressure and heart rate readings were then taken using an electronic wrist sphygmomanometer. The analysis of variance (General Linear Model) showed that overall there were no significant differences …


The Relationship Between Preference And Performance Measures Of Handedness, Rosemary K. Stephens Jul 2008

The Relationship Between Preference And Performance Measures Of Handedness, Rosemary K. Stephens

The Plymouth Student Scientist

There is great debate as to the way in which preference and performance measures of handedness are related. Some suggest that they are separable dimensions (e.g. Porac & Coren, 1981), however a bulk of evidence suggests otherwise (Annett, 1970b; 1976; 1985). The study aimed to discover whether any of three tasks were better captured by the EHI (Oldfield, 1971). Participants completed all three performance tasks and the EHI. Results suggest that performance measures tapping more practiced abilities may be better captured by preference inventories. Implications of the findings and how preference and performance measures might be related are discussed. How …


Introduction To The Plymouth Student Scientist, Mick Uttley Jul 2008

Introduction To The Plymouth Student Scientist, Mick Uttley

The Plymouth Student Scientist

No abstract provided.


Environmental Variables And Macroinvertebrate Community Structure In Drainage Ditches On The Somerset Levels, Carly Hoskin Jul 2008

Environmental Variables And Macroinvertebrate Community Structure In Drainage Ditches On The Somerset Levels, Carly Hoskin

The Plymouth Student Scientist

1. Studies of macroinvertebrate assemblages have tended to find relationships between environmental variables and the species present in the assemblage. Here, I looked at the relationship between assemblages and environmental variables in six drainage ditches in a small area of the Somerset Levels, UK. 2. I sampled aquatic macroinvertebrates and a range of environmental physicochemical variables from the six ditches, and investigated the differing relationships between the environmental variables and a range of assemblage datasets (overall assemblage, Coleoptera, Hemiptera, Odonata, and Mollusca). 3. Environmental variables surveyed were relatively homogeneous, with the exception of calcium, conductivity and nitrate. Diversity, species richness, …


An Analysis Of Dieting Methods, Fruit And Vegetable Intake, Weight Perceptions And Family Meals, In Female Adolescents, Nicola Lowles Jul 2008

An Analysis Of Dieting Methods, Fruit And Vegetable Intake, Weight Perceptions And Family Meals, In Female Adolescents, Nicola Lowles

The Plymouth Student Scientist

OBJECTIVES: The overall aim of the study was to examine relationships between dieting, ethnic origin and fruit and vegetable intake in adolescent girls, and to determine any difference in fruit and vegetable intake and eating with the family during the week and at weekends. SUBJECTS: A total of 823 female subjects participated in the study. The age range was between 12 – 16 years. 52.7% were White, 9.8% were Mixed race, 18.5% were Asian, 15.6% were Black and 2.1% were of another (Other) ethnic origin. All subjects attended low-income group schools in London and Coventry. METHODS: Two separate visits by …


The Solent Sea Breeze: Occurrence, Classification And Forecasting Aspects, Richard Lewis Jul 2008

The Solent Sea Breeze: Occurrence, Classification And Forecasting Aspects, Richard Lewis

The Plymouth Student Scientist

The Solent sea breeze was studied from May-August 2006, wind speed, direction, air and sea temperature and humidity data recorded at Bramble Bank and Dockhead was provided by the hydrographer’s office in Southampton. A Weather diary was also kept to identify and classify sea breeze events in conjunction with synoptic charts. The aim of the study is to record and classify sea breezes in the Solent from May – August 2006 and evaluate weather or not a previous forecast model originally for Thorney Island can be applied with any degree of accuracy at Calshot. The Solent sea breeze was found …


A Review Of Combined Diet And Exercise Weight Loss Interventions In Obese And Overweight Adolescents, Nicola Lowles Jul 2008

A Review Of Combined Diet And Exercise Weight Loss Interventions In Obese And Overweight Adolescents, Nicola Lowles

The Plymouth Student Scientist

No abstract provided.


Turbulent Mixing In Bottom Boundary Layer Of The Coastal Ocean, Anna Kaczmarska Jul 2008

Turbulent Mixing In Bottom Boundary Layer Of The Coastal Ocean, Anna Kaczmarska

The Plymouth Student Scientist

This paper analyses the evolution of the bottom boundary layer observed over a flood tide in the Plymouth Sound in June 2006. The overview of the energy budget associated with turbulence is presented in which an estimation of turbulent energy dissipation and production in the boundary layer is performed. Turbulent characteristics are calculated from data collected by two Acoustic Doppler Velocimeters (ADV) located at 69 cm and 52 cm above the sea bed. The same turbulent characteristics are calculated, but applying different methods, using the velocity measured by a downlooking 1200 kHz Acoustics Doppler Current Profiler (ADCP) installed at a …


Cognitive Consequences Of Perceiving Social Exclusion, Na Wyer Jul 2008

Cognitive Consequences Of Perceiving Social Exclusion, Na Wyer

School of Psychology

Although a great deal is now known about how people mentally represent individuals and groups, less attention has been paid to the question of how interpersonal relationships are represented in memory. Drawing on principles of categorization, this paper reports an investigation into how we mentally represent the relationships of others. In three experiments, evidence for assimilation effects following social exclusion (and subsequent categorization) is found. Experiment 1 uses a judgment paradigm to demonstrate that social exclusion influences the perception of interpersonal closeness. Experiments 2 and 3 employ a memory confusion paradigm to establish that representations of relationship partners are assimilated …


Your Own Actions Influence How You Perceive Other People: A Misattribution Of Action Appraisals, Sp Tipper, P Bach Jul 2008

Your Own Actions Influence How You Perceive Other People: A Misattribution Of Action Appraisals, Sp Tipper, P Bach

School of Psychology

The attribution of personal traits to other persons depends on the actions the observer performs at the same time (Bach & Tipper, 2007). Here, we show that the effect reflects a misattribution of appraisals of the observers' own actions to the actions of others. We exploited spatial compatibility effects to manipulate how fluently-how fast and how accurately-participants identified two individuals performing sporty or academic actions. The traits attributed to each person in a subsequent rating task depended on the fluency of participants' responses in a specific manner. An individual more fluently identified while performing the academic action appeared more academic …


A Guide To Medication Review, W Clyne, A Blenkinsopp, R Seal Jun 2008

A Guide To Medication Review, W Clyne, A Blenkinsopp, R Seal

Peninsula Medical School

No abstract provided.


Diffusion-Controlled Dissolution Of A Binary Solid Into A Ternary Liquid With Partially-Molten Zone Formation, Dc Hatton, Aw Woods Jun 2008

Diffusion-Controlled Dissolution Of A Binary Solid Into A Ternary Liquid With Partially-Molten Zone Formation, Dc Hatton, Aw Woods

School of Engineering, Computing and Mathematics

We build a theoretical model of equilibrium dissolution of a homogeneous, solid mixture of two salts A and B, KCl and NaCl being used as the type example, into an aqueous solution of the two salts, with diffusive transport. We find that there are two sharp dissolution fronts, separating fluid, a partially molten zone containing a single solid and mixed solid. The phase change happens almost entirely at the two sharp fronts. In equilibrium, the leading front exhibits a small amount of precipitation of NaCl, simultaneous with complete dissolution of KCl. There is a unique surface in the space of …


Post-Qualifying Social Work - Evaluation Project Stage Ii, H Donnellan, G Jack May 2008

Post-Qualifying Social Work - Evaluation Project Stage Ii, H Donnellan, G Jack

School of Health Professions

No abstract provided.


A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (Pqtls), D Melzer, Jrb Perry, D Hernandez, Et Al May 2008

A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (Pqtls), D Melzer, Jrb Perry, D Hernandez, Et Al

Peninsula Medical School

There is considerable evidence that human genetic variation influences gene expression. Genome-wide studies have revealed that mRNA levels are associated with genetic variation in or close to the gene coding for those mRNA transcripts - cis effects, and elsewhere in the genome - trans effects. The role of genetic variation in determining protein levels has not been systematically assessed. Using a genome-wide association approach we show that common genetic variation influences levels of clinically relevant proteins in human serum and plasma. We evaluated the role of 496,032 polymorphisms on levels of 42 proteins measured in 1200 fasting individuals from the …


Accessing Out-Of-Hours Care Following Implementation Of The Gms Contract: An Observational Study, Sh Richards, R Winder, D Seamark, C Seamark, Et Al May 2008

Accessing Out-Of-Hours Care Following Implementation Of The Gms Contract: An Observational Study, Sh Richards, R Winder, D Seamark, C Seamark, Et Al

School of Health Professions

BACKGROUND: There is widespread concern that the quality of out-of-hours primary care for patients with complex needs may be at risk now that the new general medical services contract (GMS) has been implemented. AIM: To explore changes in the use of out-of-hours services around the time of implementation of the new contract for patients with complex needs, using patients with cancer as an example. DESIGN OF STUDY: Longitudinal observational study. SETTING: Out-of-hours primary care provider covering Devon (adult population 900,000), UK. METHOD: Two, 1-year periods corresponding to pre- (April 2003 to March 2004) and post-contract implementation (October 2004 to September …


Affection, Virtue, Pleasure, And Profit: Developing An Understanding Of Friendship Closeness And Intimacy In Western And Asian Societies, M Gummerum, M Keller May 2008

Affection, Virtue, Pleasure, And Profit: Developing An Understanding Of Friendship Closeness And Intimacy In Western And Asian Societies, M Gummerum, M Keller

School of Psychology

The development of friendship understanding has rarely been explored from a cross-cultural perspective. In this study, children and adolescents from Iceland, China, Russia, and the former East Germany were investigated in one longitudinal and three cross-sectional samples. Children from three different Chinese ecologies were interviewed to account for within-culture variation. Participants were interviewed about friendship closeness and intimacy at ages 7, 9, 12, and 15 years. Their statements were scored according to (a) structural—developmental stages and (b) content aspects of friendship reasoning. Results reveal that the development of friendship reasoning of participants from all societies could be captured by the …


Collective Memory And Blood Feud: The Case Of Mountainous Crete, Aris Tsantiropoulos Apr 2008

Collective Memory And Blood Feud: The Case Of Mountainous Crete, Aris Tsantiropoulos

SOLON Law, Crime and History (previously SOLON Crimes and Misdemeanours: Deviance and the Law in Historical Perspective)

Drawing upon ethnographic data from mountainous central Crete, a feuding society up to the present moment, this article will focus on cases of retaliatory crimes where men avenge a relative who was killed before they were born. In these cases, what is interesting is that there do not seem to be any factors in the present to fuel the fire of a past animosity between the two kinship groups. Instead, these men seek revenge looking either for the murderer himself or for one of his male relatives in the places where they were forced to emigrate after the commitment of …


Personal Reflections On The Experiencing The Law Conference, Henry Yeomans Apr 2008

Personal Reflections On The Experiencing The Law Conference, Henry Yeomans

SOLON Law, Crime and History (previously SOLON Crimes and Misdemeanours: Deviance and the Law in Historical Perspective)

No abstract provided.


Australia And The War Against Terrorism: Terrorism, National Security And Human Rights, Mark Rix Apr 2008

Australia And The War Against Terrorism: Terrorism, National Security And Human Rights, Mark Rix

SOLON Law, Crime and History (previously SOLON Crimes and Misdemeanours: Deviance and the Law in Historical Perspective)

This article considers whether in the 'war against terrorism' national security is eroded or strengthened by weakening or removing the human rights of the individuals who constitute the polity. It starts with the view that national security is, at its most fundamental, founded upon the security and liberty of the person from criminal and violent acts, including terrorist attacks. Such attacks, and the individuals and groups who perpetrate them, constitute a grave threat to the peace and security of nations the world over and thus endanger the security and liberty of the individuals who make up their populations. Governments are …


Experiencing The Law: Activity Or Inactivity? The Law's Response To Dealing With Violence (Institute Of Advanced Legal Studies 7 December 2007), Judith Rowbotham Apr 2008

Experiencing The Law: Activity Or Inactivity? The Law's Response To Dealing With Violence (Institute Of Advanced Legal Studies 7 December 2007), Judith Rowbotham

SOLON Law, Crime and History (previously SOLON Crimes and Misdemeanours: Deviance and the Law in Historical Perspective)

No abstract provided.


Massive Autophosphorylation Of The Ser/Thr-Rich Domain Controls Protein Kinase Activity Of Trpm6 And Trpm7, K Clark, J Middelbeek, Na Morrice, Et Al Mar 2008

Massive Autophosphorylation Of The Ser/Thr-Rich Domain Controls Protein Kinase Activity Of Trpm6 And Trpm7, K Clark, J Middelbeek, Na Morrice, Et Al

School of Biomedical Sciences

TRPM6 and TRPM7 are bifunctional proteins expressing a TRP channel fused to an atypical alpha-kinase domain. While the gating properties of TRPM6 and TRPM7 channels have been studied in detail, little is known about the mechanisms regulating kinase activity. Recently, we found that TRPM7 associates with its substrate myosin II via a kinase-dependent mechanism suggesting a role for autophosphorylation in substrate recognition. Here, we demonstrate that the cytosolic C-terminus of TRPM7 undergoes massive autophosphorylation (32+/-4 mol/mol), which strongly increases the rate of substrate phosphorylation. Phosphomapping by mass spectrometry indicates that the majority of autophosphorylation sites (37 out of 46) map …


Improving Student Support In Professional Placement Learning: Findings From The South West Peninsula Pilot Of A New English National Placement Quality Assurance And Enhancement Process., Gr Williamson, V Heath, L Ballantyne, L Callaghan, D Webster, C Hunter Mar 2008

Improving Student Support In Professional Placement Learning: Findings From The South West Peninsula Pilot Of A New English National Placement Quality Assurance And Enhancement Process., Gr Williamson, V Heath, L Ballantyne, L Callaghan, D Webster, C Hunter

School of Nursing and Midwifery

English stakeholder collaboration has resulted in a new quality assurance process for non-medical health and social care placement providers and higher education institutions. This study aimed to discover the impact on student support that taking part in a pilot had on participating placement areas. Using a questionnaire survey with longitudinal follow-up one year later, we found that placement staff valued the opportunity to review and improve student support practices. This was still in evidence a year later where the pilot was described as giving the opportunity to provide evidence of aspects of student support practice; communicating and changing or developing …


The Regulation Of Sirt2 Function By Cyclin-Dependent Kinases Affects Cell Motility, R Pandithage, R Lilischkis, K Harting, A Wolf, Et Al Mar 2008

The Regulation Of Sirt2 Function By Cyclin-Dependent Kinases Affects Cell Motility, R Pandithage, R Lilischkis, K Harting, A Wolf, Et Al

School of Biomedical Sciences

Cyclin-dependent kinases (Cdks) fulfill key functions in many cellular processes, including cell cycle progression and cytoskeletal dynamics. A limited number of Cdk substrates have been identified with few demonstrated to be regulated by Cdk-dependent phosphorylation. We identify on protein expression arrays novel cyclin E–Cdk2 substrates, including SIRT2, a member of the Sirtuin family of NAD+-dependent deacetylases that targets a-tubulin. We define Ser-331 as the site phosphorylated by cyclin E–Cdk2, cyclin A–Cdk2, and p35–Cdk5 both in vitro and in cells. Importantly, phosphorylation at Ser-331 inhibits the catalytic activity of SIRT2. Gain- and loss-of-function studies demonstrate that SIRT2 interfered with cell adhesion …


The Effectiveness Of A Nationwide Intervention Programme To Prevent And Counter School Bullying In Ireland, Sj Minton, Am O'Moore Mar 2008

The Effectiveness Of A Nationwide Intervention Programme To Prevent And Counter School Bullying In Ireland, Sj Minton, Am O'Moore

School of Psychology

The purpose of this paper is to set out what is known about (large-scale empirical research) and what has been done about (large-scale whole-school intervention programmes) bullying behaviour in Irish schools, with a view to indicating likely future developments in Irish anti-bullying action. Results from a 1993 nationwide representative survey of bullying behaviour in schools (O'Moore, Kirkham & Smith, 1997) are compared with those of a hitherto unpublished survey from 2004-2005 (the 'ABC' survey). Essentially, whilst the proportion of primary students involved in bully/victim problems was lower in the 'ABC' survey (35.3%) than it was in the 1993 nationwide survey …


Regulation Of Multiple Angiogenic Pathways By Dll4 And Notch In Human Umbilical Vein Endothelial Cells, Ls Harrington, Rca Sainson, Ck Williams, Jm Taylor, Et Al Mar 2008

Regulation Of Multiple Angiogenic Pathways By Dll4 And Notch In Human Umbilical Vein Endothelial Cells, Ls Harrington, Rca Sainson, Ck Williams, Jm Taylor, Et Al

School of Biomedical Sciences

The Notch ligand, Dll4, is essential for angiogenesis during embryonic vascular development and is involved in tumour angiogenesis. Several recent publications demonstrated that blockade of Dll4 signalling inhibits tumour growth, suggesting that it may constitute a good candidate for anti-cancer therapy. In order to understand the role of Dll4 at the cellular level, we performed an analysis of Dll4-regulated genes in HUVECs. The genes identified included several angiogenic signalling pathways, such as VEGF, FGF and HGF. In particular we identified downregulation (VEGFR2, placenta growth factor PlGF) of VEGF pathway components resulting in the overall effect of limiting the response of …