Digital Commons Network^™

Cell Membrane Facilitators: Nucleotide-Amine Linkages., Michael Yiu-Ming Chan

Theses and Dissertations

In order to facilitate the transport of a nucleotide across an artificial lipid bilayer, different amines were conjugated to the phosphate group of adenosine 5$\sp\prime$-phosphate. The effect of the amine conjugation was to enhance the lipophilicity of the consequent adenosine 5$\sp\prime$-phosphoramidate derivative.The synthesis of various nucleoside 5$\sp\prime$-phosphoramidate analogs have been investigated, using different methodologies. Adenosine 5$\sp\prime$-phosphoromorpholidate, 5$\sp\prime$-phosphor(adamantyl)amidate, (n-decyl)amidate, (n-stearyl)amidate, and (1,4,7,10,13-pentaoxo-16-azacyclooctadecyl)amidate were synthesized by adopting Moffatt and Khorana's procedures. Among these phosphoramidate analogs, the adamantyl, aza-18-crown-6, and stearyl derivates have never been reported before. These amine-nucleotides were prepared by refluxing a reaction mixture of the corresponding amine (4 fold excess), …

Systems Analysis Of The Carotid Sinus Viscoelastic Properties And Their Impact On Multifiber Baroreceptor Nerve Activity, Christopher L. Taylor

Theses and Dissertations

No abstract provided.

Hormones And Behavior In Chinook Salmon (Onchorhyncus Tschawytscha) And Steelhead Trout (Salmo Gairdneri) During Smoltification, Thomas P. Mccreery

Theses and Dissertations

No abstract provided.

December 4, 1986, University Of North Dakota

University Senate Meeting Minutes

Minutes from the December 4, 1986, meeting of the University Senate. 19 pages

Education: A Universe Of Discourse, Brenda S. Engel

Teaching and Learning: The Journal of Natural Inquiry & Reflective Practice

No abstract provided.

November 1986, University Of North Dakota Alumni Association

ALL: UND Alumni Review Master List

November 1986 issue of "The University of North Dakota Alumni Review." 11 pages

Volume 69, Number 3

October 2, 1986, University Of North Dakota

University Senate Meeting Minutes

Minutes from the October 2, 1986, meeting of the University Senate. 11 pages

A Comparison Of Hypnosis And Behavioral Treatments For Obesity With One Year Follow-Up, Judith A. Haynes

Theses and Dissertations

This study was designed to examine the effects of hypnotherapy on both short-term and long-term weight loss when combined with a group behavioral weight loss program. At the beginning of the study, 38 obese female subjects (20% over normal body weight), ranging in age from 21 to 64, were randomly assigned to one of two treatment groups, one utilizing behavior therapy only and the other utilizing behavior therapy plus hypnotherapy.

The groups mot weekly for 1-1/2 hours for 8 consecutive weeks, with follow-up sessions, at 3, 6, 9, and 12 months. Twenty-eight women completed the study. The first hour in …

Dietary Restraint And The Salience Of Visual Food Cues, Jeanine Elaine Kotschwar

Theses and Dissertations

A review of the literature reveals significant changes which have oc- cured in the role posited for dieting. Once considered a simple solution for weight loss, dieting has more recently been seen as playing a causal role in the development of eating disorders. Similarly, the characteristics and behaviors once thought to be attributable to obesity have more recently been said to be by-products of dieting-induced hunger. Several authors have pointed to the influence of cognitive factors in initiating and maintaining dieting and, conversely, in abandoning restraint in eating.

The purpose of this study was to explore the influence of dietary …

Preschool Behavioral Precursors Of The Delinquency Of Juvenile Offenders: A Retrospective Study, Kay A. Halverson

Theses and Dissertations

Early behaviors of juvenile offenders and nonoffenders were studied to assess differences between the two groups. Experimental subjects were 50 youth residing in three northeastern counties of North Dakota who had committed two or more offenses. Control subjects were 50 non-offenders matched for birthdate, sex, and school. Data were collected retrospectively from both groups on Form 1 of the Louisville Behavior Checklist (LBC)» an inventory designed to detect psychopathological behaviors among preschool children. The responses were analyzed in terms of hypotheses that were designed to address (a) which scales of the LBC would show a significant difference between the offender …

A Survey Of Attitudes About Science Fairs In White Shield School, Donald R. Yellowbird

Theses and Dissertations

No abstract provided.

Computer Aided Drafting, Lou Shi-Jer

Theses and Dissertations

No abstract provided.

Daily Hassles And Uplifts In Employed And Nonemployed Women, Patricia Larsen Aamodt

Theses and Dissertations

The purpose of this study was to assess daily hassles and uplifts in women employed full time, part time, and not employed. From three pools of 100 names in each employment category, 90 subjects were randomly selected. Questionnaires related to daily hassles and uplifts and perceived stress and health were mailed to subjects and 83% of the questionnaires were returned. The resultant sample of 74 subjects was comprised of 24 full-time, 25 part-time, and 25 nonemployed women.

The means for hassles frequency, 21.52 (SD = 13.20), and intensity, 1.44 ( SD = 0.32), indicated that subjects' hassles were low and …

Learning Styles And Student Attitudes Towards Social Studies, Joyce S. Fox

Theses and Dissertations

No abstract provided.

Supplementary Income Activities Among Minnesota Public School Teachers, Janet L. Pladson

Theses and Dissertations

The Problem: This study was designed to develop profiles of Minnesota teachers who did and did not engage in supplementary income activities, profiles of teachers engaged in one, two, or three or more supplementary income activities, and to compare the differences. The study also investigated the perceived need to engage in supplementary income activities, the perceived reasons for being engaged in supplementary income activities, and the perceived impact of being engaged in supplementary income activities.

Procedure: A three percent (3%) sample of Minnesota teachers participated in a survey designed to collect information about the supplementary income activities of teachers. Resulting …

A Combination Of Approaches To The Remediation Of Learning Disabilities, Judith N. Dockter

Theses and Dissertations

No abstract provided.

School Of Medicine Commencement: May 23, 1986, University Of North Dakota

UND Commencement Programs

School of Medicine Commencement program from May 23, 1986.

Duration Estimation : A Comparison Among Three Methods Of Absolute Judgment, Rosanne B. Mcbride

Undergraduate Theses and Senior Projects

No abstract provided.

May 1986, University Of North Dakota Alumni Association

ALL: UND Alumni Review Master List

May 1986 issue of "The University of North Dakota Alumni Review." 12 pages

Volume 68, Number 9

May 1, 1986, University Of North Dakota

University Senate Meeting Minutes

Minutes from the May 1, 1986, meeting of the University Senate. 47 pages

The Right, The New Right, And The New Religious Right; Educational Positions, Postures, And Preachments, Katherine Marie Dahl

Theses and Dissertations

No abstract provided.

The Effect Of Histamine On Lanthanum (La3+) Binding In The Isolated Rabbit Heart In The Presence Of Verapamil, Scott A. Barman

Theses and Dissertations

Two of the major effects of histamine in the rabbit heart are the enhancement of contractility and microvascular permeability. In cardiac muscle it has been documented that calcium (Ca ) bound to the sarcolem- mal-glycocalyx complex is essential for the regulation of the contractile response. In addition, it has been postulated that histamine's regulation of microvascular permeability may occur via an endothelial contractile response causing the formation of submicroscopic gaps between endothelial cells. It was postulated that these effects of histamine may in- O . volve an alteration of Ca r binding to the plasma membranes of these tissues. In …

Learning Through Play In Severly And Multiply Handicapped Preschool Children, Denise D. Martell

Theses and Dissertations

No abstract provided.

The Effects Of A Cyclic Analog Of Alpha-Msh/Acth 4-10 On Reactivation Of Memory After Hypothermia Induced Amnesia, Craig R. Sprenger

Undergraduate Theses and Senior Projects

No abstract provided.

April 3, 1986, University Of North Dakota

University Senate Meeting Minutes

Minutes from the April 3, 1986, meeting of the University Senate. 24 pages

March 1986, University Of North Dakota Alumni Association

ALL: UND Alumni Review Master List

March 1986 issue of "The University of North Dakota Alumni Review." 12 pages

Volume 68, Number 7

February 6, 1986, University Of North Dakota

University Senate Meeting Minutes

Minutes from the February 6, 1986, meeting of the University Senate. 8 pages

The Effects Of Sentence Context On Event-Related Brain Potentials During Word Recognition, Jeffrey A. Harsch

Undergraduate Theses and Senior Projects

No abstract provided.

Serotonergic Mediation In The Activity Of Anticonvulsant Compounds (Neurotransmitter, Diazepam, Phenytoin)., Larry Marvin Leadbetter

Theses and Dissertations

The role of the central nervous system neurotransmitter serotonin was evaluated on the anticonvulsant activity of various compounds. Serotonin (5-hydroxytryptamine) is known to have an inhibitory role in central nervous system activity. A facilitation of the anticonvulsant activity of benzodiazepines has previously been attributed to increased serotonin activity.Male white mice of the ICR strain were administered varying doses of phenytoin, 5-ethyl, 5-methylhydantoin (EMH) and JAW-669, then challenged with maximal electroshock. The occurrence of seizures was used to evaluate the degree of protection provided by a given dose of anticonvulsant.The role of serotonin on the anticonvulsant activity of these compounds was …

Effects Of Zinc Deficiency On Sertoli Cell Number And Ultrastructure: An In Vivo And In Vitro Study., Gro Thorne-Tjomsland

Theses and Dissertations

Hypogonadism in the male is a well known clinical symptom of zinc deficiency. The testicular lesions have been primarily attributed to the effects of decreased zinc on germ cells. This study assessed possible effects of zinc deficiency on Sertoli cell number and ultrastructure.Long-Evans dams and their newborn litters were placed on zinc deficient (ZD), pair-fed or ad libitum fed (AL) diets. All dams received a 20% egg white based diet containing less than one ppm zinc. ZD dams received distilled, deionized water (<1 ppm ZN), while PF and AL dams received the above water fortified with 25 ppm zinc. Male pups were sacrificed day 10 and their testes were processed for light (LM) and transmission electron microscopy (TEM).LM cell counts were performed on one (mu)m sections. Average number of germ cells on the basement membrane (BM) (=GC2) per tubular cross-section was reducted by two-thirds in ZD and PF compared to AL animals (p < 0.0001). Average number of germ cells not on the BM (=GC1) and average number of Sertoli cells per tubular cross-section were not statistically different in the three diet groups.Volume fractions of TEM subcompartments/total cytoplasm were determined by morphometric methods. The lysosome-like fraction was doubled in ZD and PF compared to AL animals (p < 0.05). Endoplasmic reticulum, Golgi and mitochondrial fractions were not statistically different in the three diet groups.Five day old Sertoli cell cultures derived from ZD, PF and AL pups were volumetrically analyzed as in vivo. The endoplasmic reticulum fraction was approximately 100% lower in ZD- than in AL-derived cultures (p < 0.01). Golgi, mitochondrial, dense body and inclusion body fractions were similar in ZD-, PF- and AL-derived cultures.These data suggest that Sertoli cells, although not significantly reduced in number in ZD and PF animals, were affected ultrastructurally by dietary treatment. The volumetric increase in lysosome-like bodies in vivo suggested that Sertoli cells participate in phagocytosis of germ cells degenerating as a result of dietary treatment. The decreased ER volume fraction of ZD-derived tissue cultured Sertoli cells suggested that Sertoli cell secretory potential may be altered as a result of zinc deficiency.