Digital Commons Network^™

January 30, 2018, The Dakota Student

The Dakota Student

No abstract provided.

Alcohol Abuse And Mental Health Disorders In United States Veterans, Heidi Prentice

Nursing Capstones

No abstract provided.

February 1, 2018: Agenda, University Of North Dakota

University Senate Meeting Minutes

Agenda for the February 1, 2018, meeting of the University Senate. 39 pages

January 23, 2018, The Dakota Student

The Dakota Student

No abstract provided.

Volume 55, Number 22: January 17, 2018, University Of North Dakota

University Letter Archive

No abstract provided.

Translational Systems Pharmacology-Based Predictive Assessment Of Drug-Induced Cardiomyopathy, Dimitris E. Messinis, Ioannis N. Melas, Junguk Hur, Navya Varshney, Leonidas G. Alexopoulos, Jane P. F. Bai

Biomedical Sciences Faculty Publications

Drug-induced cardiomyopathy contributes to drug attrition. We compared two pipelines of predictive modeling: (1) applying elastic net (EN) to differentially expressed genes (DEGs) of drugs; (2) applying integer linear programming (ILP) to construct each drug’s signaling pathway starting from its targets to downstream proteins, to transcription factors, and to its DEGs in human cardiomyocytes, and then subjecting the genes/proteins in the drugs’ signaling networks to EN regression. We classified 31 drugs with availability of DEGs into 13 toxic and 18 nontoxic drugs based on a clinical cardiomyopathy incidence cutoff of 0.1%. The ILP-augmented modeling increased prediction accuracy from 79% to …

Effect Of Staff Education Pre-Hospital Readmission Reduction Program Implementation In A Critial Access Hospital In Rural North Dakota, Jessica Jean Larson

Nursing Capstones

No abstract provided.

An Exploration Of The Impact Of Social Support On The Parents Of Children With Autism Disorder, Elizabeth Mcdevitt

Nursing Capstones

No abstract provided.

Volume 55, Number 21: January 10, 2018, University Of North Dakota

University Letter Archive

No abstract provided.

January 11, 2018: Agenda, University Of North Dakota

University Senate Meeting Minutes

Agenda for the January 11, 2018, meeting of the University Senate. 39 pages

This meeting was cancelled due to the weather.

Evolution Of Occupational Therapy Practice: Life History Of Annie Schlecht, Motr/L, Cimi, Paige Rieger, Jordyn Himley

Oral History Posters

This life history one of 31 life history interviews which are a part of a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming, The purpose of the project is to gather information about the history and evolution of occupational therapy (OT) practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. It is anticipated that the life history process will be a powerful way to gather this information. This study is intended to provide current and …

Swat Modeling Of Non-Point Source Pollution In Depression-Dominated Basins Under Varying Hydroclimatic Conditions, Mohsen Tahmasebi Nasab, Kendall Grimm, Mohammad Hadi Bazrkar, Lan Zeng, Afshin Shabani, Xiaodong Zhang, Xuefeng Chu

Earth System Science and Policy Faculty Publications

Non-point source (NPS) pollution from agricultural lands is the leading cause of various water quality problems across the United States. Particularly, surface depressions often alter the releasing patterns of NPS pollutants into the environment. However, most commonly-used hydrologic models may not be applicable to such depression-dominated regions. The objective of this study is to improve water quantity/quality modeling and its calibration for depression-dominated basins under wet and dry hydroclimatic conditions. Specifically, the Soil and Water Assessment Tool (SWAT) was applied for hydrologic and water quality modeling in the Red River of the North Basin (RRB). Surface depressions across the RRB …

Evolution Of Occupational Therapy Practice: Life History Of Dr. Julie Grabanski, Phd, Otr/L, Sydney Gayton, Madisyn Rick

Oral History Student Papers

This qualitative study was completed in order to gather information about the history of the occupational therapy practice. The process was guided by the Kawa Model and life histories of influencers in North Dakota and Wyoming were collected. A face-to-face interview was conducted at the University of North Dakota with Dr. Julie Grabanski in order to collect this needed information. After the transcription and data analysis were complete, the student researchers discovered that Dr. Julie Grabanski has applied what she has learned from her occupational therapy education to her everyday life. It was also found that she embraces an occupational …

Vol. 43, No. 4: Holiday 2018, School Of Medicine & Health Sciences

North Dakota Medicine Archive

No abstract provided.

The Heterogeneity Of Victim Impact Statements: A Content Analysis Of Capital Trial Sentencing Penalty Phase Transcripts, Bryan Myers, Narina Nuñez, Benjamin Wilkowski, Andre Kehn, Katheirne Dunn

Psychology Faculty Publications

Victim impact statements (VISs) are controversial in capital sentencing proceedings largely due to their questionable relevance to sentencing, the concern that characterizations of the victim may lead to arbitrary sentencing judgments, and the belief that the emotional nature of this evidence may be inflammatory. A sample of 192 capital trial VIS transcripts was analyzed for content as well as a linguistic analysis of emotionality. The findings reveal that these statements are highly varied, including their format, length, and relation between the witness and the victim. Despite a legislative mandate that they address the emotional, financial, and physical suffering experienced by …

The New Anti-Federalism: Late Term Obama Environmental Regulations And The Rise Of Trump, Elizabeth Glass Geltman

North Dakota Law Review

No abstract provided.

Childhood Trauma: An Analysis Of Associated Co-Morbidities And Various Psychotherapies, Brittney L. Benson

Physician Assistant Scholarly Project Posters

American and European studies suggest that anywhere from 14 to 67% of children have experienced at least one traumatic event throughout their life. Furthermore, about 13.4% of them go on to develop post-traumatic stress disorder (PTSD) or symptoms (Diehle, J., Opmeer, B.C., Boer, F., Mannarino, A.P., & Lindauer, R.J., 2015). One study suggests that as many as 63.9% of adults suffer from ACEs (Adverse Childhood Experiences) (CDC, 2016). The 4th Edition of the Diagnostic and Statistical Manual (DSM-IV) states that PTSD is the most common Axis I disorder in children that are victims of abuse with statistics ranging from 20% …

Pre-Participation Physical Exams: Are We Doing Enough?, Steven Jacob Pietrusza

Physician Assistant Scholarly Project Posters

•Inclusion of screening electrocardiograms (EKGs) during pre-participation physical examination has been a topic of debate for some time. There is unquestioned usefulness in the ability of a well-trained health care provider in using EKG to identify cardiac abnormalities.

•Further, there have been several contemporary EKG criteria published that increase specificity and sensitivity of detection of disease. However, these criteria do not account for athletes less than 14 years of age, and that demographic represents a large portion of patients seeking pre-participation screenings in the United States.

•The lack of research into pediatric cardiac remodeling secondary to activity, coupled with the …

New Ways Of Predicting Efficacy Of Antidepressants, Kayla Ternes

Physician Assistant Scholarly Project Posters

Major depressive disorder (MDD) is a neuropsychiatric condition that is becoming increasingly prevalent in our country. According to Cai, Huang, and Hao (2015), MDD is “common and devastating” (p. 61) and has a very complex pathophysiology. Until recently, a definitive etiology had not been found, however, new evidence has suggested that Brain-derived neurotrophic factor (BDNF) and cognitive-emotional biomarkers may be a key into the mechanism of this disorder.

A literature review of articles found in PubMed, CINAHL, Cochrane Library, and PsychINFO within the last ten years focused on the hypotheses of the pathophysiology of MDD, cognitive-emotional biomarkers, and BDNF. The …

Antibiotic Therapy In Preventing Exacerbations Of Severe Chronic Obstructive Pulmonary Disease, Jamie Trautner

Physician Assistant Scholarly Project Posters

• Chronic obstructive pulmonary disease (COPD) is a progressive disease that has no cure but is treatable. The treatment goal is to have adequate symptom control, decreased exacerbations, prevent hospitalizations and maintain an independent quality of life.

• The review of literature is to determine if the benefits of long-term antimicrobial therapy outweigh the risks in the treatment of severe COPD.

• The gold standard for pharmacotherapy consists of inhaled corticosteroids and bronchodilators (long-acting beta2agonist (LABA).

• Adding azithromycin to standard therapy for patients with frequent exacerbations showed a 27% reduction in exacerbation frequency.

• With prolonged use of antimicrobials …

Evolution Of Occupational Therapy Practice: Life History Of Jan Nelson, Otr/L, Ma, Jessica Anderson, Reghan Boldt

Oral History Posters

The life history of Jan Nelson was one of 31 life history interviews conducted apart of a larger project of Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of this Life History is to gather information about the history and evolution of OT practice from individuals like Jan Nelson who have been influential in developing OT in these two states. This study is intended to provide current and future generations of occupational therapists a view of the history and how OT practice has evolved in North Dakota and …

Life History Of Gwendalyn Soiseth, Mot, Otr/L, Jessica Drady, Marissa Rahlf

Oral History Posters

The life history of Gwendalyn Soiseth was one of 31 life history interviews conducted apart of a larger project of Life Histories of Individuals Who Have Been Influential in Develop Occupational Therapy (OT) in North Dakota and Wyoming. Purpose of this Life History is to gain historical information regarding the changes in OT practice from individuals such as Gwendalyn Soiseth who have been influential in the development of OT in these two states. This study is intended to provide current and future occupational therapists a glimpse into the history of how OT practice has evolved in North Dakota and Wyoming. …

Life History Of Sclinda"Cindy" Janssen, Phd, Otr/L, Courtney Haugen, Olivia Kack

Oral History Posters

This installation is part of a larger qualitative research study entitled Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. Thepurpose of the study is to examine influential and impactful leaders within OT practice and academia. It is anticipated that the current and future members within the OT community will be able to utilize this information to inform themselves about impactful people and occurrences within OT history.

Glycemic Control And Type 1 Diabetes Mellitus: Current Standard Treatment Vs. Closed-Loop Insulin Pumps, Kelsey Daley

Physician Assistant Scholarly Project Posters

As of 2015, 9.4% of the US population had a diagnosis of Diabetes Mellitus (DM). Although most of the data sets studied encompass type 1 (T1) and type 2 (T2) DM data in all ages of patients, the focus of this project will be primarily on T1DM.

There are effective methods currently available for the management of T1DM patients. These methods include: closed-loop insulin pumps that integrate a continuous glucose monitor (CGM) and insulin pump into one effective system that calculates the needed insulin doses through complicated algorithms, CGM with self-blood glucose monitoring calibrations (SBGM) and insulin administration, and SBGM …

The Neuroprotective Effects Of Targeted Temperature Management On Post-Cardiac Arrest Patients, Timothy Hovde

Physician Assistant Scholarly Project Posters

Novel methods of ensuring survival following cardiac arrest and resuscitation are of supreme importance to the medical community. Targeted temperature management (TTM) has become increasingly utilized pre-hospital, in emergency departments, and within intensive care units to increase the likelihood of survival to hospital discharge. TTM has further been used to attempt to improve neurological functioning. The efficacy and mechanism behind TTM remains poorly understood. In several patient populations it also remains unproven. The purpose of this study is to assess the physiological mechanism, survival, neurological recovery and methodology of TTM use and implementation.

Literature review was utilized to assess the …

The Impact Of Circadian Misalignment On Cardiometabolic Health, Cynthia Marie Mills

Physician Assistant Scholarly Project Posters

The circadian system is important in all living organisms because it generates a 24-hour rhythm for physiological and behavioral processes enabling anticipation and adaptation to daily changes in the environment. The prevalence of cardiometabolic diseases, which are linked to lifestyle choices, has been rising at an alarming rate. Modernization and globalization are two of many factors to blame for lifestyle changes resulting in circadian disruption. The purpose of this literature review is to explore circadian misalignment with regards to its mechanism and impact on cardiometabolic health and to determine possible interventional measures. The primary focus is on lifestyle change, particularly …

Integrative Medicine In Primary Care, Ashley M. Bjornerud

Physician Assistant Scholarly Project Posters

Integrative medicine (IM) is an approach to care that puts the patient at the center and addresses the full range of physical, emotional, mental, social, spiritual and environmental influences that affect a person’s health (Rakel, 2017). Commonly, IM is associated with complementary and alternative medicine therapies (CAM). These are two separate entities. CAM is one of the modalities used in integrative medicine.

The Safety And Efficacy Of Creatine Supplementation In The General Public, Cody Baxter

Physician Assistant Scholarly Project Posters

The purpose of this study was to determine whether supplementation with creatine monohydrate is efficacious beyond the realm of its most popular use, which is in athletics. This study investigated the safety of creatine supplementation in the general population. References were collected through a review of PubMed and Scopus databases. Initial keywords searched were creatine supplementation and creatine safety. Where possible, trials with human subjects were utilized. Studies focused on creatine’s effects in athletes or weightlifting parameters were eliminated. Topics were further narrowed down by conditions with the most amount of research and medical concerns recognized as common to primary …

Decreased Mortality Of Pulmonary Arterial Hypertension In Duchenne Muscular Dystrophy And Down Syndrome, Mitchell Volin

Physician Assistant Scholarly Project Posters

The genetic cause of significant disorders like Down syndrome (DS) and Duchenne muscular dystrophy (DMD) is well documented. Pulmonary arterial hypertension (PAH), a co-morbid condition, is tied to mortality among these groups. Individuals with the ability to communicate their symptoms and actively participate in treatment are at an advantage with subsequent benefit. DS and DMD significantly decrease physical ability and communication capacity. Genetic research has allowed for earlier identification of, or predisposition for, the development of PAH. Work has also progressed toward manipulation at the genetic level to decrease the severity and even eradicate the cardiopulmonary disorder. This information is …

Treatment Of Subacromial Impingement Syndrome In A 53-Year-Old Female: A Case Study, Jarad Syrstad

Physical Therapy Scholarly Projects

Background and Purpose. Subacromial impingement syndrome (SAIS) is a common shoulder pathology. The purpose of this case report is to discuss the outcomes of subsequent physical therapy after operative treatment for SAIS and the clinical decision making involved in seeking surgical intervention.

Case Description. This case report describes a 54 y/o female who participated in eight weeks of physical therapy after undergoing shoulder decompression surgery while failing conservative physical therapy prior to surgical intervention.

Intervention. Physical therapy interventions were designed to strengthen the rotator cuff and shoulder, increase range of motion, decrease pain, and improve functional activity. …