Digital Commons Network^™

Examining Psilocybin And Lsd Consumption Through A Geographical Lens, Nicole Sarah Caruana

Geography ETDs

n recent years, the study of psychedelic science has reemerged across a variety of fields. Psilocybin and LSD (Lysergic Acid Diethylamide) are two psychedelic substances receiving an influx of attention for their success treating issues such as depression, post-traumatic stress, and addiction. Psilocybin and LSD are still widely used despite their classification as illegal Schedule I substance. This study aims to learn more about current users with the following questions guiding this research: What are barriers limiting psilocybin and LSD consumption? What are the motivations behind use? What impacts are psilocybin and LSD having on users lives? I used Qualitative …

Spanish /S/ Reduction In Cíbola County, New Mexico, Brandon Martinez

Linguistics ETDs

The extent to which /s/ reduces in both onset and coda positions varies greatly across Spanish varieties, with Traditional New Mexican Spanish showing significant reduction rates in past research. However, to-date there has been no in-depth linguistic study of Spanish in Cíbola County. The current work presents an analysis of variable /s/ reduction in Cíbola Spanish, using data from the New Mexico-Colorado Spanish Survey. The results demonstrate that reduction in this dialect is conditioned primarily by linguistic rather than extralinguistic factors, which vary based on syllable position. The manuscript also briefly introduces the history of Cíbola, Hispanic identity & …

The Nursing Baccalaureate Dual Enrollment Model: Outcomes For A Community College And University Partnership, Jenny B. Landen

Nursing ETDs

The partnership model in which universities collaborate with community colleges for the prelicensure Bachelor of Science (BSN) education has been identified by the National Academy of Medicine (NAM) as one of five viable academic progression models for nursing. The current literature lacks evidence on the success of these academic progression models for replication and improvement in an effort to increase the BSN-educated workforce. This retrospective descriptive study explored the differences in demographic and academic characteristics of the prelicensure BSN graduates and the differences in program outcomes from a partnership model in New Mexico which included three universities and five community …

Request For Modification 21-019 To Resource Conservation And Recovery Act (Rcra) Facility Operating Permit, Sandia National Laboratories/New Mexico (Snl/Nm), Sandia National Laboratories/Nm Snl

Facilities-Units

The Department of Energy/National Nuclear Security Administration (DOE/NNSA) and Sandia National Laboratories, New Mexico (SNL/NM) have requested modifications to the Resource Conservation and Recovery Act Facility Operating Permit (Permit) for Sandia National Laboratories/New Mexico. The requested modifications consist of revisions to the Mixed Waste Landfill (MWL) Long-Term Monitoring and Maintenance Plan (LTMMP), which is incorporated by reference into Permit Attachment M, "Long-Term Monitoring and Maintenance Plan for Solid Waste Management Units and Areas of Concern Granted Corrective Action Complete with Controls." The MWL is also known as Solid Waste Management Unit (SWMU) 76.

The DOE/NNSA and SNL/NM propose to make …

An Investigation Of Phosphorus Removal By Purple Bacteria In Dairy Wastewater Lagoons, Lauren M. Gomez, Andrew J. Schuler, Jose M. Cerrto, David T. Hanson

Civil Engineering ETDs

The objective of this study was to determine whether the polyphosphate metabolism in purple photosynthetic bacteria (PPB) is similar to that of wastewater polyphosphate-accumulating organisms (PAOs) such as Accumulibacter. Dairy lagoon samples were studied in continuous and batch laboratory tests to evaluate whether cyclic light and dark conditions for PPB are similar to aerobic and anaerobic conditions for PAOs in domestic wastewater treatment systems. 16s rRNA gene amplicon sequencing indicated the presence of the purple sulfur bacterium Thiolamprovum (53.92%) in one lagoon source, and Thiodictyon (3.50%) in a second lagoon. Phosphorus contents were at least 0.7% higher than the …

Reconfigurable Antennas & Matching Networks For Cubesats, Marios Patriotis

Electrical and Computer Engineering ETDs

Telecommunication has rapidly evolved in the past decades, quickly becoming one of the most expansive industries, especially with the presence of new attractive eras like 5Gnetworks, automotive radars, and CubeSats. The use of miniaturized satellites such as CubeSats for cheaper and wider communication coverage has opened the possibilities for cluster satellite communication. These units exist in a continuously varying environment as much physical as electromagnetic. Hence, the establishment of a successful communication link among the space units but also ground stations becomes challenging. This new situation can be confronted with the installation of new reconfigurable antennas. These are emitting units …

Ipedition Fall 2021, The Unm Hsc Inter-Professional Education Team

The IPE Newsletters

No abstract provided.

Editorial: Thrombotic Microangiopathies, Diagnostic And Therapeutic Advances, Robert W. Maitta, Jay S. Raval, Hollie M. Reeves, Magali J. Fontaine

Pathology Research and Scholarship

No abstract provided.

Glomerular Disease In Temporal Association With Sars-Cov-2 Vaccination: A Series Of 29 Cases, Tiffany N. Caza, Clarissa A. Cassol, Nidia Messias, Andrew Hannoudi, Randy S. Haun, Patrick D. Walker, Rebecca M. May, Regan M. Seipp, Elizabeth J. Betchick, Hassan Amin, Mandolin S. Ziadie, Michael Haderlie, Joy Eduwu-Okwuwa, Irina Vancea, Melvin Seek, Essam B. Elashi, Ganesh Shenoy, Sayeed Khalillullah, Jesse A. Flaxenburg, John Brandt, Matthew J. Diamond, Adam Frome, Eugene H. Kim, Gregory Schlessinger, Erlandas Ulozas, Janice L. Weatherspoon, Ethan Thomas Hoerschgen, Steven L. Fabian, Sung Yong Bae, Bilal Iqbal, Kanwalijit K. Chouhan, Zeina Karam, James T. Henry, Christopher P. Larsen

Pediatrics Research and Scholarship

Background: Immune responses to vaccination are a known trigger for a new onset of glomerular disease or disease flare in susceptible individuals. Mass immunization against SARS-CoV-2 in the COVID-19 pandemic provides a unique opportunity to study vaccination-associated autoimmune kidney diseases. In the recent literature, there are several patient reports demonstrating a temporal association of SARS-CoV-2 immunization and kidney diseases.

Methods: Here, we present a series of 29 cases of biopsy-proven glomerular disease in patients recently vaccinated against SARS-CoV-2 and identified patients who developed a new onset of IgA nephropathy, minimal change disease, membranous nephropathy, ANCA-associated GN, collapsing glomerulopathy, or diffuse …

Egfr Transactivates Ron To Drive Oncogenic Crosstalk, Carolina Franco Nitta, Ellen W. Green, Elton D. Jhamba, Justine M. Keth, Iraís Ortiz-Caraveo, Rachel M. Grattan, David J. Schodt, Aubrey C. Gibson, Ashwani Rajput, Keith A. Lidke, Bridget S. Wilson, Mara P. Steinkamp, Diane S. Lidke

Pathology Research and Scholarship

Crosstalk between different receptor tyrosine kinases (RTKs) is thought to drive oncogenic signaling and allow therapeutic escape. EGFR and RON are two such RTKs from different subfamilies, which engage in crosstalk through unknown mechanisms. We combined high-resolution imaging with biochemical and mutational studies to ask how EGFR and RON communicate. EGF stimulation promotes EGFR-dependent phosphorylation of RON, but ligand stimulation of RON does not trigger EGFR phosphorylation - arguing that crosstalk is unidirectional. Nanoscale imaging reveals association of EGFR and RON in common plasma membrane microdomains. Two-color single particle tracking captured formation of complexes between RON and EGF-bound EGFR. Our …

11-30-2021 Hsc Committee Agenda, Hsc Committee

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Nuanced Networks: How Social Relationships And Power Influence Participation In Private Lands Conservation Programs, Ellen Loechner

Geography ETDs

Because the majority of land in the Midwestern United States is privately owned, the responsibility for creating and maintaining space for wildlife conservation falls upon private landowners. Numerous state and federal agencies and non-governmental organizations (NGOs) host private lands conservation programs that offer landowners financial and technical support to complete conservation projects on their property (Echols, Front, and Cummins 2019). While the individual motivations and priorities of a landowner may inform how they use and manage their property, a landowner’s ability to connect with the agricultural and conservation communities may determine if they have the opportunity to participate in these …

Microrna Analysis Of Human Stroke Brain Tissue Resected During Decompressive Craniectomy/Stroke-Ectomy Surgery, Andrew P. Carlson, William Mckay, Jeremy S. Edwards, Radha Swaminathan, Karen S. Santacruz, Ron L. Mims, Howard Yonas, Tamara Roitbak

Pathology Research and Scholarship

BACKGROUND: Signaling pathways mediated by microRNAs (miRNAs) have been identified as one of the mechanisms that regulate stroke progression and recovery. Recent investigations using stroke patient blood and cerebrospinal fluid (CSF) demonstrated disease-specific alterations in miRNA expression. In this study, for the first time, we investigated miRNA expression signatures in freshly removed human stroke brain tissue.

METHODS: Human brain samples were obtained during craniectomy and brain tissue resection in severe stroke patients with life-threatening brain swelling. The tissue samples were subjected to histopathological and immunofluorescence microscopy evaluation, next generation miRNA sequencing (NGS), and bioinformatic analysis.

RESULTS: miRNA NGS analysis detected …

Crisis, Cooperation, And Coercion: Migration Diplomacy In Europe, 2014-2017, Jessica L. Jones

Political Science ETDs

In this dissertation I ask when and how states employ migration diplomacy – and its coercive and cooperative variants – during the European Migration Crisis, 2014-2017. I argue that states use migration diplomacy to minimize the costs of migration crises and are more likely to use migration diplomacy when either the incurred or anticipated costs of migration crises are greater, when they are less powerful, and when anti-migrant domestic political pressures are higher. I use a multimethod approach to answer my questions. Results from my multivariate logistic regressions support my expectation that states are more likely to engage in migration …

Interferometric Lithography- An Approach To Large Area And Cost Effective Nanopatterning, Vineeth Sasidharan

Optical Science and Engineering ETDs

In this dissertation interferometric lithography is approached in two different ways to address two important constraints of nanopatterning. One approach solves the problem of scaling up interferometric lithography to wafer scale (4 inch or larger) area. Through the second approach we have developed a nanopatterning technique based on interferometric lithography by using an inexpensive (~$100) diode laser as source, making interferometric lithography a very cost-effective technique.

Wafer-scale large-area nanopatterning was developed using an amplitude grating mask as a grating beam splitter along with spatial averaging of laser intensity by wobbling. The longitudinal and transverse coherence issues both are eased by …

20211122_Zines Care, Colonialism, And Health Happening November 29th-December 3rd, Kelleen Maluski

HSLIC Blog Post

No abstract provided.

A Novel Algorithm Using Cell Population Data (Vcs Parameters) As A Screening Discriminant Between Alpha And Beta Thalassemia Traits, Angeli Ambayya, Santina Sahibon, Thoo Wei Yang, Qian-Yun Zhang, Rosline Hassan, Jameela Sathar

Pathology Research and Scholarship

Thalassemia is one of the major inherited haematological disorders in the Southeast Asia region. This study explored the potential utility of red blood cell (RBC) parameters and reticulocyte cell population data (CPD) parameters in the differential diagnosis of α and β-thalassaemia traits as a rapid and cost-effective tool for screening of thalassemia traits. In this study, a total of 1597 subjects (1394 apparently healthy subjects, 155 subjects with α-thalassaemia trait, and 48 subjects with β-thalassaemia trait) were accrued. The parameters studied were the RBC parameters and reticulocyte CPD parameters derived from Unicel DxH800. A novel algorithm named αβ-algorithm was developed: …

20211122_Hslic's Biomedical Informatics Seminar Series Presents- Melissa Rethlefsen, Msls, Tamara Wheeler

HSLIC Blog Post

No abstract provided.

Bioengineered Models To Study Microenvironmental Regulation Of Glioblastoma Metabolism, Joseph Chen, Hyunchul Lee, Philipp Schmitt, Caleb J. Choy, Donald M. Miller, Brian J. Williams, Elaine L. Bearer, Hermann B. Frieboes

Pathology Research and Scholarship

Despite extensive research and aggressive therapies, glioblastoma (GBM) remains a central nervous system malignancy with poor prognosis. The varied histopathology of GBM suggests a landscape of differing microenvironments and clonal expansions, which may influence metabolism, driving tumor progression. Indeed, GBM metabolic plasticity in response to differing nutrient supply within these microenvironments has emerged as a key driver of aggressiveness. Additionally, emergent biophysical and biochemical interactions in the tumor microenvironment (TME) are offering new perspectives on GBM metabolism. Perivascular and hypoxic niches exert crucial roles in tumor maintenance and progression, facilitating metabolic relationships between stromal and tumor cells. Alterations in extracellular …

20211117_24 7 Study Is Coming Soon To All Floors, Kristin R. Proctor

HSLIC Blog Post

No abstract provided.

Open-Ish Access:" Collaborative Solutions For Sensitive Information In Unm's Native Health Database, Jonathan M. Pringle

Posters and Presentations

No abstract provided.

Relief And Reward Drinking Across Time In Community And Treatment-Seeking Samples, Julia E. Swan

Psychology ETDs

Classifying people with alcohol use disorder into homogenous groups based on observed characteristics (i.e., phenotypes) could match individuals to specific treatments. The reward-relief phenotype classifies individuals based on whether they drink to enhance rewarding experiences and/or to relieve negative states. The current study is a secondary data analysis of a community sample of non-treatment seeking heavy drinkers (n = 189) and two randomized clinical trial samples of individuals with alcohol use disorder (n = 1726, 1383) that aimed to determine if the reward-relief phenotype is identified across samples, is stable over time, and predicts long-term alcohol consumption and consequences. We …

Essays On Human Capital, Soumyajit Chakraborty

Economics ETDs

The first essay: Agriculture in Nepal is the most critical sector for economic growth – it directly benefits the poor, and a considerable proportion of the population derives their livelihoods from agriculture. This essay uses the 2017–2018 baseline survey data from Nepal Seed and Fertilizer (NSAF) project funded through the USAID’s “Feed the Future” program. The essay explores a causal relationship between agronomical knowledge and productivity-enhancing farming decisions. Evidence indicates that there are significant, consistent, and positive returns to agronomical knowledge via engaging in advisory contact through traditional agricultural extension. Given the drawback of the institutional irregularity of advisory services, …

Recruitment Machines, Community Power And Political Return On Investment (Proi): Economic Development Policy In The Age Of Amazon, Eric G. Griego Montoya

Political Science ETDs

ABSTRACT

A fundamental policy choice in economic development among local policy makers is the appropriate mix of “outside” strategies that use incentives to attract companies, and “inside” strategies that invest in smaller and local businesses. Using a mixed-methods research design, including national and state surveys along with qualitative analysis of interviews conducted with policy elites, I examine the role of ideology, elites, community, competition, social capital (trust and influence), and electoral politics in these policy decisions. I use new descriptive theoretical frameworks called “recruitment machines” and “Political Return on Investment (PROI)” to describe how and why local elected officials support …

Comparative Phylogeography Across Multiple Scales: Small Mammals, Their Ecology, Pathogens, And Drivers Of Diversification, Schuyler W. Liphardt

Biology ETDs

Comparative phylogeography has historically been defined as the study of how genetic variation of co-distributed species has been shaped by biogeographical history. This is a mature field of study out of which several techniques have been developed directed at identifying the role ecology and geography in diversification patterns across time. I employ the tools developed in classical comparative phylogeography across multiple taxonomic scales and across regions that historically have been understudied. My first two chapters study the complex history of host-switching, codiversification, and reassortment of hantaviruses in their mammal hosts across North America. By taking a host-centric comparative phylogeographic approach …

The Profound Photophysical Effects Of Organic Chromophore Connectivity And Coupling, David J. Walwark Jr

Nanoscience and Microsystems ETDs

Through-bond and through-space interactions between chromophores are shown to have wide-ranging effects on photophysical outcomes upon light absorption in organic molecules. In collapsed poly(3-hexylthiophene), through-space coupling creates hybrid chromophores that act as energy sinks for nearby excitons and favorable sites for molecular oxygen to dock. Upon excitation with visible light the highly-coupled chromophores react with the docked oxygen and subsequently do not quench nearby excitons as efficiently. In tetramer arrays of perylene diimide chromophores the central moiety through-bond connectivity is synthesized in two variants which exhibit vastly different single-molecule blinking behavior and theoretically-predicted electronic transition character. In the more-connected tetramer …

Silica Sol-Gel Control With High Voltage Contactless Electrodes, Jonathan C. Hebert

Nanoscience and Microsystems ETDs

High Voltage Contactless Electrodes (HVE) non-evasively modulates silica sol-gel reactions by redistributing charge in solution. HVE induces formation of local neutral band (LNB) strata (pseudo interfacial surfaces) where the gradient of potential is zero ∇𝜓𝜓=0. HVE LNB shape corresponds to solubility and ultimately sol-gel form. HVE silica sol-gel control works by localizing pH and creating conditions where silanol polymerization is biform; condensation by protonation (cathodic), or by deprotonation (anodic). Steric modified Poisson-Boltzmann equation is used to develop a theory on HVE control of silica sol-gel formation and a nucleate potential functional of potential 𝜓𝜓. Technologies developed during this research are …

Three-Dimensional Lattices As Effective Impact Absorption Layers For Space Applications, James Youchison

Mechanical Engineering ETDs

Additive manufacturing (AM) is increasingly becoming a viable manufacturing process due to dramatic advantages that it facilitates in the material selection and design complexity. This paper investigates the potential of additively manufactured lattice structures for the application of dissipating impact energy. In this research the role of geometry and material properties on the static and dynamic energy absorption properties of additively manufactured wave spring lattices composed of various materials were studied under drop/impact and compression tests. A finite element simulation of the lattice structure was also conducted, although the results were overall inconclusive, it gave some great insight into the …

Intersectionality, Relational Positionality, And The Lived Experiences Of Inequality: Contextualizing Intergenerational Opioid Use And The Constrained Choices Of Indigenous, Latina, And White Women Caregivers In Rural New Mexico, Carmela M. Roybal

Sociology ETDs

Opioid addiction is a serious and persistent global health issue. The federal Centers for Disease Control and Prevention (CDC) reported that between 1999 and 2016, more than 630,000 people in the United States died of an overdose of a prescription opioid or illicit drug (CDC 2018). Extant research has suggested that for nearly a century, New Mexico has experienced some of the highest rates of prescription and illicit opioid death in the nation (Goldstein and Herrera, 1995; Landon, 2003; Shah et al., 2008). I examined intergenerational opioid dependence through the lived experience of women caregivers of opioid-addicted family members. Data …

Cyber Physical Systems For Non-Contact Infrastructure Monitoring, Roya Nasimi

Civil Engineering ETDs

In recent decades, the decay of infrastructure has become a relevant challenge of both developed and under developing countries. Prioritization of maintenance and repairs of transportation infrastructure is a new worldwide priority since it is important to quantify the rate of decay of assets to increase both safety and cost-efficient operations. Infrastructure owners need frequent inspections on their assets to predict and to avoid unsafe conditions prone to cause disasters. Frequent infrastructure inspections call for cost-effective methods. Traditional measurement methods require human access to the infrastructure, are subjective, expensive, and unsafe. Therefore, infrastructure managers are interested in exploring new non-contact …