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Researching Covid To Enhance Recovery (Recover) Adult Study Protocol: Rationale, Objectives, And Design, Leora I Horwitz, Tanayott Thaweethai, Shari B Brosnahan, Mine S Cicek, Megan L Fitzgerald, Jason D Goldman, Rachel Hess, S L Hodder, Vanessa L Jacoby, Michael R Jordan, Jerry A Krishnan, Adeyinka O Laiyemo, Torri D Metz, Lauren Nichols, Rachel E Patzer, Anisha Sekar, Nora G Singer, Lauren E Stiles, Barbara S Taylor, Shifa Ahmed, Heather A Algren, Khamal Anglin, Lisa Aponte-Soto, Hassan Ashktorab, Ingrid V Bassett, Brahmchetna Bedi, Nahid Bhadelia, Christian Bime, Marie-Abele C Bind, Lora J Black, Andra L Blomkalns, Hassan Brim, Mario Castro, James Chan, Alexander W Charney, Benjamin K Chen, Li Qing Chen, Peter Chen, David Chestek, Lori B Chibnik, Dominic C Chow, Helen Y Chu, Rebecca G Clifton, Shelby Collins, Maged M Costantine, Sushma K Cribbs, Steven G Deeks, John D Dickinson, Sarah E Donohue, Matthew S Durstenfeld, Ivette F Emery, Kristine M Erlandson, Julio C Facelli, Rachael Farah-Abraham, Aloke V Finn, Melinda S Fischer, Valerie J Flaherman, Judes Fleurimont, Vivian Fonseca, Emily J Gallagher, Jennifer C Gander, Maria Laura Gennaro, Kelly S Gibson, Minjoung Go, Steven N Goodman, Joey P Granger, Frank L Greenway, John W Hafner, Jenny E Han, Michelle S Harkins, Kristine S P Hauser, James R Heath, Carla R Hernandez, On Ho, Matthew K Hoffman, Susan E Hoover, Carol R Horowitz, Harvey Hsu, Priscilla Y Hsue, Brenna L Hughes, Prasanna Jagannathan, Judith A James, Janice John, Sarah Jolley, S E Judd, Joy J Juskowich, Diane G Kanjilal, Elizabeth W Karlson, Stuart D Katz, J Daniel Kelly, Sara W Kelly, Arthur Y Kim, John P Kirwan, Kenneth S Knox, Andre Kumar, Michelle F Lamendola-Essel, Margaret Lanca, Joyce K Lee-Lannotti, R Craig Lefebvre, Bruce D Levy, Janet Y Lin, Brian P Logarbo, Jennifer K Logue, Michele T Longo, Carlos A Luciano, Karen Lutrick, Shahdi K Malakooti, Gail Mallett, Gabrielle Maranga, Jai G Marathe, Vincent C Marconi, Gailen D Marshall, Christopher F Martin, Jeffrey N Martin, Heidi T May, Grace A Mccomsey, Dylan Mcdonald, Hector Mendez-Figueroa, Lucio Miele, Murray A Mittleman, Sindhu Mohandas, Christian Mouchati, Janet M Mullington, Girish N Nadkarni, Erica R Nahin, Robert B Neuman, Lisa T Newman, Amber Nguyen, Janko Z Nikolich, Igho Ofotokun, Princess U Ogbogu, Anna Palatnik, Kristy T S Palomares, Tanyalak Parimon, Samuel Parry, Sairam Parthasarathy, Thomas F Patterson, Ann Pearman, Michael J Peluso, Priscilla Pemu, Christian M Pettker, Beth A Plunkett, Kristen Pogreba-Brown, Athena Poppas, J Zachary Porterfield, John G Quigley, Davin K Quinn, Hengameh Raissy, Candida J Rebello, Uma M Reddy, Rebecca Reece, Harrison T Reeder, Franz P Rischard, Johana M Rosas, Clifford J Rosen, Nadine G Rouphael, Dwight J Rouse, Adam M Ruff, Christina Saint Jean, Grecio J Sandoval, Jorge L Santana, Shannon M Schlater, Frank C Sciurba, Caitlin Selvaggi, Sudha Seshadri, Howard D Sesso, Dimpy P Shah, Eyal Shemesh, Zaki A Sherif, Daniel J Shinnick, Hyagriv N Simhan, Upinder Singh, Amber Sowles, Vignesh Subbian, Jun Sun, Mehul S Suthar, Larissa J Teunis, John M Thorp, Amberly Ticotsky, Alan T N Tita, Robin Tragus, Katherine R Tuttle, Alfredo E Urdaneta, P J Utz, Timothy M Vanwagoner, Andrew Vasey, Suzanne D Vernon, Crystal Vidal, Tiffany Walker, Honorine D Ward, David E Warren, Ryan M Weeks, Steven J Weiner, Jordan C Weyer, Jennifer L Wheeler, Sidney W Whiteheart, Zanthia Wiley, Natasha J Williams, Juan P Wisnivesky, John C Wood, Lynn M Yee, Natalie M Young, Sokratis N Zisis, Andrea S Foulkes Jan 2023

Researching Covid To Enhance Recovery (Recover) Adult Study Protocol: Rationale, Objectives, And Design, Leora I Horwitz, Tanayott Thaweethai, Shari B Brosnahan, Mine S Cicek, Megan L Fitzgerald, Jason D Goldman, Rachel Hess, S L Hodder, Vanessa L Jacoby, Michael R Jordan, Jerry A Krishnan, Adeyinka O Laiyemo, Torri D Metz, Lauren Nichols, Rachel E Patzer, Anisha Sekar, Nora G Singer, Lauren E Stiles, Barbara S Taylor, Shifa Ahmed, Heather A Algren, Khamal Anglin, Lisa Aponte-Soto, Hassan Ashktorab, Ingrid V Bassett, Brahmchetna Bedi, Nahid Bhadelia, Christian Bime, Marie-Abele C Bind, Lora J Black, Andra L Blomkalns, Hassan Brim, Mario Castro, James Chan, Alexander W Charney, Benjamin K Chen, Li Qing Chen, Peter Chen, David Chestek, Lori B Chibnik, Dominic C Chow, Helen Y Chu, Rebecca G Clifton, Shelby Collins, Maged M Costantine, Sushma K Cribbs, Steven G Deeks, John D Dickinson, Sarah E Donohue, Matthew S Durstenfeld, Ivette F Emery, Kristine M Erlandson, Julio C Facelli, Rachael Farah-Abraham, Aloke V Finn, Melinda S Fischer, Valerie J Flaherman, Judes Fleurimont, Vivian Fonseca, Emily J Gallagher, Jennifer C Gander, Maria Laura Gennaro, Kelly S Gibson, Minjoung Go, Steven N Goodman, Joey P Granger, Frank L Greenway, John W Hafner, Jenny E Han, Michelle S Harkins, Kristine S P Hauser, James R Heath, Carla R Hernandez, On Ho, Matthew K Hoffman, Susan E Hoover, Carol R Horowitz, Harvey Hsu, Priscilla Y Hsue, Brenna L Hughes, Prasanna Jagannathan, Judith A James, Janice John, Sarah Jolley, S E Judd, Joy J Juskowich, Diane G Kanjilal, Elizabeth W Karlson, Stuart D Katz, J Daniel Kelly, Sara W Kelly, Arthur Y Kim, John P Kirwan, Kenneth S Knox, Andre Kumar, Michelle F Lamendola-Essel, Margaret Lanca, Joyce K Lee-Lannotti, R Craig Lefebvre, Bruce D Levy, Janet Y Lin, Brian P Logarbo, Jennifer K Logue, Michele T Longo, Carlos A Luciano, Karen Lutrick, Shahdi K Malakooti, Gail Mallett, Gabrielle Maranga, Jai G Marathe, Vincent C Marconi, Gailen D Marshall, Christopher F Martin, Jeffrey N Martin, Heidi T May, Grace A Mccomsey, Dylan Mcdonald, Hector Mendez-Figueroa, Lucio Miele, Murray A Mittleman, Sindhu Mohandas, Christian Mouchati, Janet M Mullington, Girish N Nadkarni, Erica R Nahin, Robert B Neuman, Lisa T Newman, Amber Nguyen, Janko Z Nikolich, Igho Ofotokun, Princess U Ogbogu, Anna Palatnik, Kristy T S Palomares, Tanyalak Parimon, Samuel Parry, Sairam Parthasarathy, Thomas F Patterson, Ann Pearman, Michael J Peluso, Priscilla Pemu, Christian M Pettker, Beth A Plunkett, Kristen Pogreba-Brown, Athena Poppas, J Zachary Porterfield, John G Quigley, Davin K Quinn, Hengameh Raissy, Candida J Rebello, Uma M Reddy, Rebecca Reece, Harrison T Reeder, Franz P Rischard, Johana M Rosas, Clifford J Rosen, Nadine G Rouphael, Dwight J Rouse, Adam M Ruff, Christina Saint Jean, Grecio J Sandoval, Jorge L Santana, Shannon M Schlater, Frank C Sciurba, Caitlin Selvaggi, Sudha Seshadri, Howard D Sesso, Dimpy P Shah, Eyal Shemesh, Zaki A Sherif, Daniel J Shinnick, Hyagriv N Simhan, Upinder Singh, Amber Sowles, Vignesh Subbian, Jun Sun, Mehul S Suthar, Larissa J Teunis, John M Thorp, Amberly Ticotsky, Alan T N Tita, Robin Tragus, Katherine R Tuttle, Alfredo E Urdaneta, P J Utz, Timothy M Vanwagoner, Andrew Vasey, Suzanne D Vernon, Crystal Vidal, Tiffany Walker, Honorine D Ward, David E Warren, Ryan M Weeks, Steven J Weiner, Jordan C Weyer, Jennifer L Wheeler, Sidney W Whiteheart, Zanthia Wiley, Natasha J Williams, Juan P Wisnivesky, John C Wood, Lynn M Yee, Natalie M Young, Sokratis N Zisis, Andrea S Foulkes

Pediatrics Research and Scholarship

IMPORTANCE: SARS-CoV-2 infection can result in ongoing, relapsing, or new symptoms or other health effects after the acute phase of infection; termed post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID. The characteristics, prevalence, trajectory and mechanisms of PASC are ill-defined. The objectives of the Researching COVID to Enhance Recovery (RECOVER) Multi-site Observational Study of PASC in Adults (RECOVER-Adult) are to: (1) characterize PASC prevalence; (2) characterize the symptoms, organ dysfunction, natural history, and distinct phenotypes of PASC; (3) identify demographic, social and clinical risk factors for PASC onset and recovery; and (4) define the biological mechanisms underlying PASC pathogenesis. …


Brain Structural Differences In Children With Fetal Alcohol Spectrum Disorder And Its Subtypes, Theresah Boateng, Kathryn Beauchamp, Faerl Torres, Chaselyn D. Ruffaner-Hanson, John Fl Pinner, Kishore Vakamudi, Cassandra Cerros, Dina E. Hill, Julia M. Stephen Jan 2023

Brain Structural Differences In Children With Fetal Alcohol Spectrum Disorder And Its Subtypes, Theresah Boateng, Kathryn Beauchamp, Faerl Torres, Chaselyn D. Ruffaner-Hanson, John Fl Pinner, Kishore Vakamudi, Cassandra Cerros, Dina E. Hill, Julia M. Stephen

Pediatrics Research and Scholarship

INTRODUCTION: The teratogenic effects of prenatal alcohol exposure (PAE) have been examined in animal models and humans. The current study extends the prior literature by quantifying differences in brain structure for individuals with a fetal alcohol spectrum disorder (FASD) compared to typically developing controls, as well as examining FASD subtypes. We hypothesized the FASD group would reveal smaller brain volume, reduced cortical thickness, and reduced surface area compared to controls, with the partial fetal alcohol syndrome (pFAS)/fetal alcohol syndrome (FAS) subtypes showing the largest effects and the PAE/alcohol-related neurodevelopmental disorder (ARND) subtype revealing intermediate effects.

METHODS: The sample consisted of …


Unm-Och Diabetes Project Data Set, Janet Page-Reeves, Lidia Regino, Erik B. Erhardt, Cristina Murray-Krezan, Blanca Pedigo, Maria Tellez, Mark R. Burge, Shiraz I. Mishra, Elaine Bearer, Molly J. Bleecker, Denise Guerrero, Daniel P. Rodriguez Jan 2023

Unm-Och Diabetes Project Data Set, Janet Page-Reeves, Lidia Regino, Erik B. Erhardt, Cristina Murray-Krezan, Blanca Pedigo, Maria Tellez, Mark R. Burge, Shiraz I. Mishra, Elaine Bearer, Molly J. Bleecker, Denise Guerrero, Daniel P. Rodriguez

Family Community Medicine

Background

Latinos who live in poverty are at high risk for type 2 diabetes (diabetes). Health guidelines recommend strategies for self-management, but many people find lifestyle change to be challenging. Systematic reviews show that culturally competent self-management programs that take values, customs, beliefs, and language from Latino culture into account can significantly improve diabetes outcomes.

Objectives

We compared the effectiveness of two distinct evidence-based models of culturally competent diabetes health promotion: 1) The Diabetes Self-Management Support Empowerment Model (DSMS), an approach using a classroom-based educational sessions taught by trained diabetes educators, and 2) The Chronic Care Model (CCM), a holistic …


University Of New Mexico Health Sciences Center Discovery Research Annual Report 2023, Michael Haederle, Claire Hannon, Elizabeth Dwyer Sandlin, Nicole San Roman, Chris Ramirez, Brianna Wilson, Jett Loe, Sara Mota, Sarah Head Jan 2023

University Of New Mexico Health Sciences Center Discovery Research Annual Report 2023, Michael Haederle, Claire Hannon, Elizabeth Dwyer Sandlin, Nicole San Roman, Chris Ramirez, Brianna Wilson, Jett Loe, Sara Mota, Sarah Head

Research Annual Reports

Research annual report from the University of New Mexico Health Sciences Center.


Investigating The Potential Effect Of Pollinators On The Alpine Plant Diversity Of The Southern Rocky Mountains: A Community Phylogenetic Approach, Jeremiah Westerman Jan 2023

Investigating The Potential Effect Of Pollinators On The Alpine Plant Diversity Of The Southern Rocky Mountains: A Community Phylogenetic Approach, Jeremiah Westerman

2024 Award Winners

No abstract provided.


Harnessing Axonal Transport To Map Reward Circuitry: Differing Brain-Wide Projections From Medial Prefrontal Cortical Domains, Elaine L. Bearer, Christopher S. Medina, Taylor W. Uselman, Russell E. Jacobs Jan 2023

Harnessing Axonal Transport To Map Reward Circuitry: Differing Brain-Wide Projections From Medial Prefrontal Cortical Domains, Elaine L. Bearer, Christopher S. Medina, Taylor W. Uselman, Russell E. Jacobs

Pathology Research and Scholarship

Neurons project long axons that contact other distant neurons. Neurons in the medial prefrontal cortex project into the limbic system to regulate responses to reward or threat. Diminished neural activity in prefrontal cortex is associated with loss of executive function leading to drug use, yet the specific circuitry that mediate these effects is unknown. Different regions within the medial prefrontal cortex may project to differing limbic system nuclei. Here, we exploited the cell biology of intracellular membrane trafficking, fast axonal transport, to map projections from two adjacent medial prefrontal cortical regions. We used Mn(II), a calcium analog, to trace medial …


Reduced Time To Procedure For Gastrointestinal Bleeding After Warfarin Reversal With Four-Factor Complex Concentrate As Compared To Plasma, Hannah Spector, Hannah L. Mcrae, Tanzy Love, Kalynn Northam, Khaled Refaai, Marian A. Rollins-Raval, Majed A. Refaai Jan 2023

Reduced Time To Procedure For Gastrointestinal Bleeding After Warfarin Reversal With Four-Factor Complex Concentrate As Compared To Plasma, Hannah Spector, Hannah L. Mcrae, Tanzy Love, Kalynn Northam, Khaled Refaai, Marian A. Rollins-Raval, Majed A. Refaai

Pathology Research and Scholarship

BACKGROUND: Bleeding is a serious adverse effect of vitamin K antagonists (VKAs). Anticoagulation reversal is required in some acute cases. This is usually accomplished by plasma transfusion or four-factor prothrombin complex concentrate (4F-PCC). The aim of this study was to gain insight into the clinical course of patients with gastrointestinal (GI) bleeding who require VKA reversal.

METHODS: Medical records were collected from two centers from patients who presented to the emergency department (ED) for GI bleeding and received 4F-PCC or plasma for VKA reversal between January 2015 and December 2020. ED, hospital, intensive care unit (ICU) length of stay (LOS) …


Effects Of A Psychological Stressor On Methamphetamine Seeking In Rats., Kayla B. Cox Jan 2023

Effects Of A Psychological Stressor On Methamphetamine Seeking In Rats., Kayla B. Cox

Psychology ETDs

Although methamphetamine abuse and fatality rates are on the rise in the United States, there are currently no FDA approved drugs to treat methamphetamine use disorder (MUD). To better understand factors contributing to addiction, researchers have designed various rodent models of stress including the use of footshock, social defeat and maternal separation, however, these models involve physical or early life stress exposure and thus are less translatable to human psychological stress. The present study implemented predatory odors as a model of psychological stress and examined whether chronic exposure to these stressors enhanced subsequent vulnerability to a subthreshold dose of methamphetamine. …


[Research Note] The Random Somatic Mutation Is Not Quite Random, Florentin Smarandache Jan 2023

[Research Note] The Random Somatic Mutation Is Not Quite Random, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This research note challenges the idea that Random Somatic Mutations are entirely random, highlighting their non-equiprobable nature and their influence on evolution, involution, or indeterminacy. It recalls the Neutrosophic Theory of Evolution, extending Darwin’s theory, and emphasizes the importance of distinguishing between different senses of “random mutation” in evolutionary theory.


Pathways To Sustainability: Industry, Development, Business, Agriculture, Economy, And Politics, Andreas Hernandez, Pablo Arias-Benavides, Dayana C.M. Machada, Ousmane Pame, Alice Main, Per Moller Jan 2023

Pathways To Sustainability: Industry, Development, Business, Agriculture, Economy, And Politics, Andreas Hernandez, Pablo Arias-Benavides, Dayana C.M. Machada, Ousmane Pame, Alice Main, Per Moller

Geography and Environmental Studies Faculty Publications

In this chapter we examine six compelling on-the-ground experiences, which are demonstrating pathways to sustainability, resilience and regeneration. Each case opens a pathway to sustainability in a key sphere of human activity: industry, development, business, agriculture, economy and politics. These experiences are creating new social imaginaries embodied in the practical forms of new politics and economics aimed at profound democratizations of human life, and towards a creative realignment of humans with the rest of the web of life. These social imaginaries are both open and encompassing. They are open in the sense that they can be filled with new possibilities …


Beyond Negation And Excluded Middle: An Exploration To Embrace The Otherness Beyond Classical Logic System And Into Neutrosophic Logic, Florentin Smarandache, Victor Christianto Jan 2023

Beyond Negation And Excluded Middle: An Exploration To Embrace The Otherness Beyond Classical Logic System And Into Neutrosophic Logic, Florentin Smarandache, Victor Christianto

Branch Mathematics and Statistics Faculty and Staff Publications

As part of our small contribution in dialogue toward better peace development and reconciliation studies, and following Toffler & Toffler’s War and Antiwar (1993), the present article delves into a realm of logic beyond the traditional confines of negation and the excluded middle principle, exploring the nuances of "Otherness" that transcend classical and Nagatomo logics. Departing from the foundational premises of classical Aristotelian logic systems, this exploration ventures into alternative realms of reasoning, specifically examining Neutrosophic Logic and Klein bottle logic (cf. Smarandache, 2005). The study challenges conventional boundaries and explores the implications of embracing paradoxes and self-reference in logic …


Race, Gender, And Class Conscious Approaches To Mentoring, Verónica C. Gonzales Jan 2023

Race, Gender, And Class Conscious Approaches To Mentoring, Verónica C. Gonzales

Faculty Scholarship

A presentation designed to teach attendees how to understand how identity is relevant to academic rigor and other "colorblind" standards; to learn best practices for mentoring students from traditionally underrepresented and excluded groups; and how to apply social justice frameworks to enhance diverse mentor-mentee relationships and outcomes.


Masking Vulnerability: Including Ppe As A Covered Service In Health Insurance, Mary Leto Pareja Jan 2023

Masking Vulnerability: Including Ppe As A Covered Service In Health Insurance, Mary Leto Pareja

Faculty Scholarship

The COVID-19 pandemic laid bare the shared vulnerability inherent in the human condition, prompting a collective recognition of our physical susceptibility to infectious diseases. While great strides have been made in combating COVID-19 through vaccinations and treatments, a portion of the population remains profoundly vulnerable due to health conditions that make the disease more dangerous, that limit vaccine efficacy, or that prevent vaccination altogether. This article explores a path forward by proposing a solution within health benefit plans—encompassing both private health insurance and public health benefits. Specifically, the article advocates for a coverage mandate for over-the-counter personal protective equipment (PPE) …


Heat Stressed Exercise Elicits Shifts In Cooling Strategies Across Body Mass In Tropical Songbirds, Kristen Dee Oliver Dec 2022

Heat Stressed Exercise Elicits Shifts In Cooling Strategies Across Body Mass In Tropical Songbirds, Kristen Dee Oliver

Biology ETDs

In resting animals, water use positively correlates with metabolic rate, for example smaller animals using proportionally more water per gram of body mass. However, animals also must endure heat and exertion, and evaporative cooling requires additional water use that may not scale similarly with body size. How evaporative water loss allometrically scales with body mass during heat-stressed exercise is poorly resolved, particularly for birds, yet is critically important for understanding the consequences of climate warming on the fitness of bird populations. Here, we evaluated how air temperature (Ta) influenced evaporative water loss during exercise (EWLexercise) across …


Acquired And Useful Abilities: Three Essays On Human Capital Development, Rajan Bishwakarma Dec 2022

Acquired And Useful Abilities: Three Essays On Human Capital Development, Rajan Bishwakarma

Economics ETDs

While early childhood circumstances influence the accumulation of skills and abilities, parental and policy responses can magnify or mitigate the effects of childhood circumstances. This work explores the two ideas mentioned above.

Chapter 1 briefs the historical and philosophical roots of the study of human capital and discusses the economic approach to the understanding of child wellbeing before the age of five. Because childhood circumstances influence the accumulation of skills, Chapter 2 estimates the impact of temperature shock during pregnancy on early childhood health. Evidence from Nepal shows that prenatal exposure to high-temperature days impedes child growth; however, the damage …


Inhibition Of Rad18 By Arsenic, Lindsay B. Volk Dec 2022

Inhibition Of Rad18 By Arsenic, Lindsay B. Volk

Biomedical Sciences ETDs

Arsenite exposure leads to the retention of UV-induced DNA damage, thus burdening translesion synthesis (TLS). Rad18 is an essential factor in initiating TLS through PCNA monoubiquitination and is implicated in homologous recombination. It contains two functionally and structurally distinct zinc fingers that are potential targets for arsenite binding. Results from this study reveal arsenite binding to both zinc fingers of Rad18 and a corresponding loss of domain function. Importantly, arsenite inhibited Rad18 RING-dependent PCNA monoubiquitination and polymerase eta recruitment to DNA damage. Further analysis demonstrated multiple effects of arsenite, including the reduction in the nuclear localization and UV-induced chromatin recruitment …


Spatial Single-Cell Identification Of Cell Layers Within Mouse Brain Using A Novel Spatially Resolved Transcriptomics Technology, Radha Swaminathan Dec 2022

Spatial Single-Cell Identification Of Cell Layers Within Mouse Brain Using A Novel Spatially Resolved Transcriptomics Technology, Radha Swaminathan

Biomedical Engineering ETDs

Spatially resolved transcriptomics technologies investigate gene expression in the context of a tissue. While imaging-based technologies enable gene expression quantification at a single-cell level, only two NGS-based technologies are currently capable of single-cell resolution. Both Stereo-seq and Seq-Scope involve two rounds of sequencing: one to sequence the location of spatial barcodes and the other to obtain sequence of cDNA. Thus, the objective of the research study is to develop a technology that can capture transcripts from every cell of a tissue without the need for two rounds of sequencing. To this end, a capture surface or barcoded array (similar to …


Formation And Interrogation Of A Modeling Excel Database For Sorbent Preconcentrate With Gc/Ms, Lisa Caravello Dec 2022

Formation And Interrogation Of A Modeling Excel Database For Sorbent Preconcentrate With Gc/Ms, Lisa Caravello

Chemical and Biological Engineering ETDs

Volatile organic compounds (VOCs) are of great interest and the subject of much research, as they can be used in various applications. Preconcentrating this class of analytes is necessary as they can be elusive with simple sampling techniques. VOCs are often captured using sorbents in thermal desorption tubes as preconcentrates prior to analysis, commonly gas chromatography mass spectroscopy (GCMS). There are gaps in knowledge in behavior of materials used as sorbents i.e., if they will retain an analyte of interest appropriately. In this research I seek to eliminate speculation and unknown variables of analyte and sorbent combinations by creating a …


Racial And Ethnic Differences In The Receipt Of Metabolic Syndrome Risk Factor Screening And Treatment Among Prostate Cancer Patients Treated With Androgen Deprivation Therapy., Yazan K. Barqawi Dec 2022

Racial And Ethnic Differences In The Receipt Of Metabolic Syndrome Risk Factor Screening And Treatment Among Prostate Cancer Patients Treated With Androgen Deprivation Therapy., Yazan K. Barqawi

Pharmaceutical Sciences ETDs

Background: Racial and ethnic health disparities in prostate cancer prevalence, incidence, mortality, quality of life, screening, and treatment constitute the largest of all cancer disparities. These health disparities are associated with higher morbidity and mortality rates in minority populations. Treatment with androgen deprivation therapy (ADT) has been the most widely used therapeutic modality to reduce the progression of prostate cancer to a worse disease stage and relieve potential obstructive symptoms. However, ADT is associated with possible toxic metabolic and cardiovascular (CVS) adverse events that may occur within six months of ADT initiation. These adverse events include metabolic syndrome, type II …


Source Estimation Of The Reward Positivity And Related Resting State Network Activity In Major Depressive Disorder, Christopher J.H. Pirrung Dec 2022

Source Estimation Of The Reward Positivity And Related Resting State Network Activity In Major Depressive Disorder, Christopher J.H. Pirrung

Psychology ETDs

Anhedonia is a complex symptom of Major Depressive Disorder (MDD) that presents itself through multiple behavioral phenotypes of diminished reward processing. In order to better understand this deficit, we aim to look at a marker of reward that is sensitive to information content and valence, the Reward Positivity (RewP). The source of this signal is, however, up for debate. This study used concurrent EEG and MEG to establish the source of the RewP as a distributed network involving ventromedial prefrontal cortex (vmPFC), anterior midcingulate cortex (aMCC), and insulae. Additionally, only vmPFC showed a deficit in MDD. fMRI resting state functional …


Interdisciplinary Integrative Oncology, Naomi L. Valles Dec 2022

Interdisciplinary Integrative Oncology, Naomi L. Valles

InterProfessional Education Research and Scholarship

No abstract provided.


Traumatic Brain Injury And Psychopathy In Incarcerated Men And Women, Tessa Cappelle Dec 2022

Traumatic Brain Injury And Psychopathy In Incarcerated Men And Women, Tessa Cappelle

Psychology ETDs

Traumatic brain injury (TBI) is one of the most suffered injuries with detrimental effects on the individual’s health, personality, and behavior. Overlap exists between TBI sequelae and symptoms of psychopathy. Both conditions are especially prevalent in incarcerated populations which makes studying their interrelation critical. Two studies examined the relationship between history of TBI (TBI+ vs. TBI-) and psychopathy (via the Hare Psychopathy Checklist-Revised; PCL-R) in adult incarcerated men and women at correctional facilities in New Mexico and Wisconsin. Study 1 included 342 women, study 2 included 1049 men. Measurement invariance was evident for TBI+ and TBI- for both studies. TBI+ …


Exploring The Role Of Dieting Style In Nutritional And Psychological Health Among College Women, Hayley L. Vanderjagt Dec 2022

Exploring The Role Of Dieting Style In Nutritional And Psychological Health Among College Women, Hayley L. Vanderjagt

Psychology ETDs

The current study aimed to profile styles of eating among dieting and non-dieting college-aged women, and to explore the extent to which dieting attitudes were associated with both nutritionally healthy eating and psychological well-being. A latent profile analysis was conducted using indicators of self-reported intuitive eating, binge eating, and two psychometric measures of dietary restraint; various measures of eating restraint were utilized to potentially capture distinct characteristics of dieting, such as self-discipline and disinhibition (Polivy et al., 2020; Stice et al., 2010). Four distinct probabilistic profiles emerged, indicating that individuals within the study population could be meaningfully categorized as Intuitive …


Fabrication, Characterization, And Simulation Of Graphene-Copper Electrical Conductors, Raju Prasad Ghimire Dec 2022

Fabrication, Characterization, And Simulation Of Graphene-Copper Electrical Conductors, Raju Prasad Ghimire

Nanoscience and Microsystems ETDs

The addition of nanocarbons to copper (Cu), specifically in the form of graphene (GN), has been shown to enhance copper's properties. GN-Cu nanocomposites can potentially achieve higher electrical, mechanical, and thermal properties compared with copper. These characteristics make GN-Cu materials interesting for several applications including but not limited to interconnects, high voltage lines, and rotating machines. Copper’s microstructure and nanoscale interfacial phenomena between the GN and Cu control charge conduction in GN-Cu materials. In this work, we investigated the possibilities of conductivity enhancement in multi-layered GN-Cu composites both theoretically (classical, quantum, and atomistic models) and experimentally.

Additionally, our work elucidates …


How South Asian Activists Queer The Model Minority Myth: A Critical Oral History Project, Noorie Baig Dec 2022

How South Asian Activists Queer The Model Minority Myth: A Critical Oral History Project, Noorie Baig

Communication ETDs

The model minority myth (MMM) is predicated on stereotypical perceptions of Asian Americans as subservient high-achievers who comply with the ideologies of meritocracy, whiteness, and capitalism. However, South Asian American (SAA) activists and community organisers, the focus of this study, are working to confront and abolish racist, heterosexist, and other exclusionary injustices, policies, and practices. This dissertation seeks to understand the historical influences of the MMM, the challenges SAA activists and organisers face, and the communication strategies they use to negotiate the MMM through their activism. Oral history methods and critical thematic analysis are used to elicit and analyse personal …


Agent-Based Modeling Predicts Rac1 Is Critical For Ovarian Cancer Metastasis, Melanie Rivera, Leslie Toledo-Jacobo, Elsa Romero, Tudor I. Oprea, Melanie E. Moses, Laurie G. Hudson, Angela Wandinger-Ness, Martha M. Grimes Dec 2022

Agent-Based Modeling Predicts Rac1 Is Critical For Ovarian Cancer Metastasis, Melanie Rivera, Leslie Toledo-Jacobo, Elsa Romero, Tudor I. Oprea, Melanie E. Moses, Laurie G. Hudson, Angela Wandinger-Ness, Martha M. Grimes

Pathology Research and Scholarship

Experimental and computational studies pinpoint rate-limiting step(s) in metastasis governed by Rac1. Using ovarian cancer cell and animal models, Rac1 expression was manipulated, and quantitative measurements of cell-cell and cell-substrate adhesion, cell invasion, mesothelial clearance, and peritoneal tumor growth discriminated the tumor behaviors most highly influenced by Rac1. The experimental data were used to parameterize an agent-based computational model simulating peritoneal niche colonization, intravasation, and hematogenous metastasis to distant organs. Increased ovarian cancer cell survival afforded by the more rapid adhesion and intravasation upon Rac1 overexpression is predicted to increase the numbers of and the rates at which tumor cells …


Assessing Knowledge And Perceptions About Cancer Among American Indians Of The Zuni Pueblo, Nm, Safia Safi, Donica Ghahate, Jeanette Bobelu, Andrew L. Sussman, Joseph Rodman, Angela Wandinger-Ness, Shiraz I. Mishra, Thomas Faber, Cheryl Willman, Vallabh Shah Dec 2022

Assessing Knowledge And Perceptions About Cancer Among American Indians Of The Zuni Pueblo, Nm, Safia Safi, Donica Ghahate, Jeanette Bobelu, Andrew L. Sussman, Joseph Rodman, Angela Wandinger-Ness, Shiraz I. Mishra, Thomas Faber, Cheryl Willman, Vallabh Shah

Pathology Research and Scholarship

American Indians (AIs) in New Mexico have lower cancer screening rates compared to other populations and are more likely to be diagnosed with cancer at an advanced stage of the disease as reported by Li et al. (Archives of Internal Medicine 163(1):49-56, 2003). AIs also have the lowest 5-year cancer survival rates compared to any ethnic/racial group in the USA as reported by Clegg et al. (Arch Intern Med 162:1985-1993, 2002) and Edwards et al. (Cancer 97:1407-1427, 2005). Numerous barriers such as cultural beliefs, fear, fatalism, mistrust, stigma, and lack of culturally appropriate interventions could contribute to low cancer screening …


Sensitivites Of Dryland Mammals To Mean And Variance In Aridity, Jessica C. Johnson Dec 2022

Sensitivites Of Dryland Mammals To Mean And Variance In Aridity, Jessica C. Johnson

Biology ETDs

An important component of evaluating the consequences of climate change is to understand not only how climate trends, such as warming, affect species abundance but also how increasing climate variability will change population abundances. Studies on species' sensitivities to interannual variability are rare because they require long-term data collected either over naturally variable climate conditions or within direct manipulations of year-to-year variability. Physiology, functional traits, and diet composition related to resource acquisition or reproduction may be valuable predictors of species sensitivities to changes in both climate mean and variability. We predicted that species with certain physiologies, such as large body …


Would You Make It To The Future? Teaching Race In An Assisted Reproductive Technologies And The Law Classroom, Sonia Gipson Rankin Dec 2022

Would You Make It To The Future? Teaching Race In An Assisted Reproductive Technologies And The Law Classroom, Sonia Gipson Rankin

Faculty Scholarship

Would you make it to the future? For the last five years, I have started my Assisted Reproductive Technology (ART) lecture in Family Law with this question. Students take the query seriously. They ponder their lived experiences such as home training, medical history, education, financial well-being, personality traits, work ethic, and social graces when determining if they would be the “model DNA” someone might select in a future society. The good-natured jokes about being nearsighted, having a pitiful jump shot, and wearing orthodontic headgear turn reflective when someone raises the question: would someone in the future select my race? In …


A Suggested Data Structure For Transparent And Repeatable Reporting Of Bibliographic Searching, Neal R. Haddaway, Melissa L. Rethlefsen, Melinda Davies, Julie Glanville, Bethany Mcgowan, Kate Nyhan, Sarah Young Dec 2022

A Suggested Data Structure For Transparent And Repeatable Reporting Of Bibliographic Searching, Neal R. Haddaway, Melissa L. Rethlefsen, Melinda Davies, Julie Glanville, Bethany Mcgowan, Kate Nyhan, Sarah Young

Publications

Academic searching is integral to research activities: (1) searching to retrieve specific information, (2) to expand our knowledge iteratively, (3) and to collate a representative and unbiased selection of the literature. Rigorous searching methods are vital for reliable, repeatable and unbiased searches needed for these second and third forms of searches (exploratory and systematic searching, respectively) that form a core part of evidence syntheses. Despite the broad awareness of the importance of transparency in reporting search activities in evidence syntheses, the importance of searching has been highlighted only recently and has been the explicit focus of reporting guidance (PRISMA-S). Ensuring …