Digital Commons Network^™

Mechanisms For The Spread Of Antibiotic Resistance In Tuberculosis, Julie Allison Spencer

Shared Knowledge Conference

Tuberculosis (TB) is currently the ninth leading cause of death for humans worldwide, causing 10.4 million new infections in 2016. According to the World Health Organization, of these infections, 600,000 were antibiotic resistant. However, the treatment success rate for resistant TB was only 54%. The potential for emergent epidemics of drug resistant TB highlights the need to understand the mechanisms for the spread of resistance. Mycobacterium tuberculosis, the bacterium that causes TB, evolves resistant strains within individuals who are being treated with antibiotics. It has been assumed previously that the resistant characteristics of these strains are spread primarily by the …

Improving The Palatability Of Colonoscopy Preparations, Phuong Anh Hoang Nguyen, Sarah Mounho, Darnell Cuylear, Heather Canavan

Shared Knowledge Conference

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States. The most reliable screening method of CRC is a colonoscopy which requires a 4-Liter polymer with electrolytes preparation. Two in five patients are non-compliant to their colonoscopy schedules, with many patients who abstain reporting refusal due to significant discomfort associated with this preparation. Furthermore, there are distinct gender differences in the tolerance of colonoscopy preparations in male and female populations. We hypothesize the differences in clinic are a result of toxic effects of the drug associated with poor mixing by individual patients. PEG, the drug, …

20181101_Journal Subscription Cancellations For 2019, Karen R. Mcelfresh

HSLIC Blog Post

No abstract provided.

Synthesis, Characterization And Application Of Structurally Diverse Poly(Chalcogenylene Vinylene)S, Zhen Zhang

Chemistry and Chemical Biology ETDs

Conjugated polymers have found widespread applications in flexible and printable electronic devices, among which poly(thienylene vinylene) (PTV) displays outstanding optoelectronic properties and promising applications. However, further studies of its structure-property-function relationship have been greatly impeded mainly due to the synthetic difficulty of generating new structures beyond its rudimentary form.

To further investigate this class of material, I have developed a facile methodology for the preparation of structurally diverse poly(chalcogenylene vinylene)s (PCVs) through a combination of acyclic diene metathesis (ADMET) polymerization and post-polymerization modification techniques. Specifically, a series of halogenated and cross-conjugated PCVs have been designed and synthesized, followed by complete …

20181029_Biomedical Informatics Seminar Series Presents Yan Guo, Phd - 11-01, Sally Bowler-Hill

HSLIC Blog Post

No abstract provided.

A Few Surprises About Non-Locality Interactions, Precognitive Interdiction, And The Spirit From Physics Viewpoint, Victor Christianto, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

There are various supernatural phenomena which hardly can be explained by the existing electromagnetic science, for instance non-locality interactions (may be associated with ESP etc), and also precognitive interdictions. And there are other problems such as how to include the Spirit in our consciousness. For example, it has been known for long time that intuition plays significant role in many professions and human life, including in entrepreneurship, government, and also in detective or law enforcement activities. Despite these examples, such a precognitive interdiction is hardly accepted in established science. In this paper, we discuss non-locality interactions and also advanced solutions …

The Tetraspanin Cd82 Regulates Hematopoietic Stem Cell Fitness And Bone Marrow Retention, Chelsea Alyssa Kimiko Saito-Reis

Biomedical Sciences ETDs

The maintenance of the hematopoietic stem and progenitor cell (HSPC) population is critical to sustaining the adult blood and immune system throughout an organism’s lifespan. The bone marrow microenvironment plays a key role in the regulation of HSPC maintenance and functions. Previous work from our lab has identified the tetraspanin CD82 as an important modulator of HSPC interactions with the bone marrow niche. However, the mechanisms as to how CD82 contributes to the maintenance, trafficking and retention of HSPCs with the niche remained unclear. First, we investigated how CD82 promotes HSPC quiescence, homing and engraftment using a global CD82 knock …

Eating The Ocean By Elspeth Probyn, Annie Brethour

Natural Resources Journal

No abstract provided.

Three Alternatives For Managing Free-Roaming Horses And Burros: A Legal Reform, C.J. Michaels

Natural Resources Journal

The Wild Free-Roaming Horses and Burros Act is overdue for repeal or revision. The Wild Horse and Burro Program is expensive for taxpayers, detrimental to rangelands, and harmful to the thousands of free-roaming equines it is intended to benefit. For nearly half a century, the Bureau of Land Management and United States Forest Service have struggled to balance the mandates of the Wild Free-Roaming Horses and Burros Act amidst a political and social climate that makes compliance impossible. Forty-six years after the Act was passed, the agencies are further from arriving at a solution than they have ever been. The …

Quantitative Validation Of Simulated Sea Ice Displacements, Bryan R. Mccormick

Mathematics & Statistics ETDs

Accurate simulations of Arctic sea ice are important for forecasting as well as for understanding the global climate. However, quantitative measures for simulation displacements are underutilized. We present five such measures proposed as being useful in the validation of simulated sea ice displacements. Using drifting buoy and satellite measurements of sea ice motion as observation, we apply the metrics in a comparison of observed displacements and predicted displacements from the Arctic sea ice simulation MPM\_ice. We find the metric scores are useful for comparing simulations and observations. The metrics also brought to light problems in the simulation MPM_ice, demonstrating their …

How Wide Is Wide Enough?: Science, Values, And Law In Riparian Habitat Conservation, George Wilhere, Timothy Quinn

Natural Resources Journal

Difficult environmental policy issues often elicit fervent declarations to “follow the science.” Such declarations ignore the essential role of values in policy making. The main purpose of this article is to clarify the relationships among science, values, and law in environmental policy. An important policy issue in wildlife conservation, is determining “how much is enough?” That is, what is the smallest amount of habitat or minimum population size that is adequate for the long-term survival of wildlife populations? This paper presents three case studies in which policy makers decided how much was enough for protecting freshwater salmonid habitats. The case …

The Last Oil: Students Respond, Unm Department Of Art

Art and Art History Faculty Publications

In February 2018, the University of New Mexico (UNM) convened the last oil: a multispecies justice symposium on Arctic Alaska and beyond.Twenty-nine artists, activists, attorneys, scientists, conservationists, curators, scholars, and writers from across the United States and Canada, gave talks and/or did creative performances—and ten colleagues from UNM and beyond chaired various sessions. the last oil was the first national convening to apprehend the reckless U.S. federal Arctic policy, and also brought impacts of climate change and Indigenous rights concerns in Alaska into conversation with similar impacts and struggles in New Mexico and the west.

Published on Indigenous …

Nuclear Engineering 2018 Apr Self-Study & Documents, University Of New Mexico

UNM Academic Program Review

UNM Nuclear Engineering APR self-study and review team report for Fall 2018, fulfilling requirements of the Higher Learning Commission.

Southwest Talks: The Taos Commune Movement Fifty Years Later, Iris Keltz

New Mexico Historical Review

No abstract provided.

Anthropology 2018 Apr Self-Study & Documents, University Of New Mexico

UNM Academic Program Review

UNM Anthropology APR self-study and review team report for Fall 2018, fulfilling requirements of the Higher Learning Commission.

Book Reviews

New Mexico Historical Review

No abstract provided.

Comparison Of Methodologies Of Using Colorimetry To Detect Low Concentrations Of Bromide As A Hydrologic Tracer, Emily Wolf

Water Resources Professional Project Reports

The objective of this research was to compare colorimetric methods for measuring low concentrations of bromide in natural waters. The bromide ion has long been used as a tracer to study hydrodynamic processes and properties. Its conservative nature makes it ideal as a tracer. Bromide is almost entirely immune to loss from a solution via adsorption on rocks and sediments, or reaction with other solutes present in the water. Using three methodologies to use colorimetry in the detection of bromide, I analyzed samples taken from the Gila River, Jemez Creek, and the Rio Grande after injections of sodium bromide were …

Non-Locality, Precognition & Spirit From The Physics Point Of View, Florentin Smarandache, Victor Christianto

Branch Mathematics and Statistics Faculty and Staff Publications

There are various supernatural phenomena which can hardly be explained by the existing mainstream science, for instance non-local interactions (e.g. ESP) and also precognitive interdictions. And there are other problems such as how to include the Spirit in the framework of physics. For example, it has been known for long time that intuition plays significant role in many professions and human life, including entrepreneurship, government, and also in detective or law enforcement activities. Despite these examples, such a precognitive interdiction is hardly accepted in mainstream science. In this paper, we discuss non-local interactions and advanced solutions of Maxwell equations, and …

How Many Points Are There In A Line Segment? A New Answer From Discrete Cellular Space Viewpoint, Florentin Smarandache, Victor Christianto

Branch Mathematics and Statistics Faculty and Staff Publications

While it is known that Euclid’s five axioms include a proposition that a line consists at least of two points, modern geometry avoid consistently any discussion on the precise definition of point, line, etc. It is our aim to clarify one of notorious question in Euclidean geometry: how many points are there in a line segment? – from discrete-cellular space (DCS) viewpoint. In retrospect, it may offer an alternative of quantum gravity, i.e. by exploring discrete gravitational theories. To elucidate our propositions, in the last section we will discuss some implications of discrete cellular-space model in several areas of interest: …

Radiation Effects In Metal Oxides And Carbides, Benjamin Jackson Cowen

Nuclear Engineering ETDs

MD simulations of SiO₂, TiO₂, Cr₂O₃, Al₂O₃, MgO, and SiC, are performed to: (a) calculate TDE probability distributions and dependence on crystallographic direction, and (b) determine the number and types of defects formed with low- and high-energy PKAs and projectiles. In addition, a qualitative comparison of the MD simulation results of radiation damage in TiO₂, MgO, and crystalline and amorphous SiC thin films are compared with those of in situ TEM ion beam irradiation experiments at the Sandia National Laboratories’ I³TEM facility.

The TDE …

Role Of Caregiver-Reported Outcomes In Identification Of Children With Prenatal Alcohol Exposure During The First Year Of Life, Ludmila N Bakhireva, Jean Lowe, Laura M Garrison, Sandra Cano, Yuridia Leyva, Fares Qeadan, Julia M Stephen

Pediatrics Research and Scholarship

BACKGROUND: Earlier identification of children with prenatal alcohol exposure (PAE) remains a challenge. The objective of this study was to identify neurobehavioral (NB) outcomes associated with PAE in infants.

METHODS: This manuscript evaluates NB outcomes at 6.33±1.12 months of age in 93 infants (39 PAE and 54 No-PAE) recruited prospectively into the ENRICH cohort. PAE was assessed by prospective repeated TLFB interviews and a panel of ethanol biomarkers. NB outcomes were evaluated by the Bayley Scales of Infant Development (BSID-III), Parenting Stress Index (PSI), Infant Behavior Questionnaire (IBQ-R), and Infant Sensory Profile (ISP).

RESULTS: Mean maternal age at enrollment was …

20180831_Hslic Welcomes New Members To Its Team, Sally Bowler-Hill

HSLIC Blog Post

No abstract provided.

Intraspecific Floral Color Variation As Perceived By Pollinators And Non-Pollinators: Evidence For Pollinator-Imposed Constraints?, Kellen Cedar Paine

Biology ETDs

Pollinator-mediated selection is expected to constrain floral color variation within plant populations, yet populations with high color variability are common in nature. To explore this, we collected floral reflectance spectra for 34 populations of 14 plant species of New Mexico, USA, and translated them into three different visual spaces. We found evidence that the majority comparisons were indistinguishable to bees, the dominant pollinator group. We also found that floral color variation was significantly greater for two non-pollinating groups, birds and humans. Our results suggest that a portion of human-perceived floral color variation within populations persists because it is invisible to …

Sociocultural Diversity In The Prehispanic Southwest: Learning, Weaving, And Identity In The Chaco Regional System, A.D. 850-1140, Edward Alexander Jolie

Anthropology ETDs

Between about A.D. 850 and 1140, the archaeology of Chaco Canyon in northwestern New Mexico reveals the rapid construction of large communal structures where smaller settlements had existed previously and shows that the locality became the core of an extensive regional system in the Four Corners region of the northern Southwest integrated by formal trails, the circulation of nonlocal goods, and the sharing of ritual items. Researchers vigorously debate the role of increased sociopolitical complexity in this development, but less attention has been given to questions of sociocultural diversity and its impacts.

Guided by previous research suggesting the existence of …

Translating Global Nature: Territoriality, Environmental Discourses, And Ecocultural Identities, José R. Castro-Sotomayor

Communication ETDs

In this study, I explore environmental discourses circulating among Indigenous transboundary organizations working on environmental initiatives at the border between Ecuador and Colombia. I focus on three global environmental discourses –sustainability, development, and climate change– as they are at the core of the global environmental governance vernacular. La Gran Familia Awá Binacional (GFAB), one of the few transboundary Indigenous organizations working along the binational border, utilizes these global concepts to frame their environmental initiatives and projects. I use a critical and interpretive qualitative approach to investigate, deconstruct, and rearticulate global environmental discourses circulating among and translated by two of the …

2017 Annual Report, Christopher C. Witt

Annual Reports

No abstract provided.

Hemocyanin-Like 1 Protein, Unique To Planorbid Snails, Supports Reproductive Output Of Biomphalaria Glabrata, Vector Of Schistosomiasis, Janeth Julieta Peña

Biology ETDs

The Neotropical freshwater snail, Biomphalaria glabrata is a major intermediate host of the parasite Schistosoma mansoni, causative agent of human intestinal schistosomiasis. Disease control efforts consist mainly of mass drug treatment but it is recognized that targeting of the snail vector is essential to prevent parasite transmission that leads to rapid (re)infections. This dissertation combines the knowledge of basic snail biology with modern molecular techniques including protein analysis, next-generation sequencing, proteomics, qRT-PCR and RNA interference to: (1) characterize hemocyanin-like genes in B. glabrata, in particular with further description of the egg mass fluid (EMF) protein hemocyanin-like 1 (Hcl-1), (2) …

Surface-Water Groundwater Interactions In The Middle Rio Grande, Nm Implications For Bank Storage And Native Species, Tom Heller

Water Resources Professional Project Reports

Riparian zones are important for ecological purposes and ecosystem processes, and are valued for aesthetic, recreational, cultural, and historical reasons. The declining integrity of cottonwood-dominated riparian systems in the Middle Rio Grande (MRG) of central New Mexico has been evident for several decades, of which the largest cause has been the severe alterations riparian hydrology. While cottonwood germination responses to changing flood regimes have been well studied, the response to changing groundwater dynamics - and the suitability of groundwater regimes in the MRG - is less well understood. This study used pressure transducer groundwater datasets installed in the Rio Grande …

Opportunities To Enhance Environmental Flows On The Rio Chama, Anjali Bean

Water Resources Professional Project Reports

The construction of El Vado dam on the Rio Chama in 1935 dramatically changed the natural flow of the river, reducing spring runoff and summer scouring floods in favor of providing a constant water supply to downstream users. The San Juan-Chama Project, a trans-basin water diversion built as part of the Colorado River Compact, also significantly increased water flow in the river, a unique situation in the state of New Mexico. This increase in management of the river for human benefit has permanently altered the natural hydrograph of the river and the ecology and geomorphology of the system that depends …

The Fate Of Xylem-Transported Co2 In Plants, Samantha S. Stutz, David T. Hanson

Biology ETDs

The concentration of carbon dioxide in tree stems can be ~30-750 times higher than current atmospheric [CO2]. Dissolved inorganic carbon enters the xylem from root and stem respiration and travels with water through the plant. However, the fate of much of this xylem-transported CO2 is unknown. In these studies I examined the fate of xylem-transported CO2 traveling through the petiole and leaf. This was accomplished by placing cut leaves from a woody and herbaceous C3 species, and a Kranz-type C4 species, in a solution of dissolved NaH13CO3 at concentrations similar to those measured in nature. This allowed me to track …